Xiang Su San

Cyperus and Perilla Leaf Powder · 香蘇散

Also known as: Xiang Su Powder, Cyperus and Perilla Formula

A gentle formula for common colds accompanied by digestive discomfort. It is designed for people who catch a chill and develop symptoms like chills, mild fever, headache, and a stuffy feeling in the chest and stomach with poor appetite. Because of its mild nature and safety during pregnancy, it is one of the most widely used classical cold remedies in Chinese medicine.

Origin Tai Ping Hui Min He Ji Ju Fang (太平惠民和剂局方) — Sòng dynasty, first published ~1078 CE, revised through 1151 CE
Composition 4 herbs
Zi Su Ye
King
Zi Su Ye
Xiang Fu
Deputy
Xiang Fu
Chen Pi
Assistant
Chen Pi
Gan Cao
Envoy
Gan Cao
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Educational content Consult qualified TCM practitioners for diagnosis and treatment

Patterns Addressed

In TCM, symptoms don't appear randomly — they cluster into recognizable patterns of disharmony that reveal what's out of balance in the body. Xiang Su San is designed to correct these specific patterns.

Why Xiang Su San addresses this pattern

When Wind-Cold invades the body's surface but the pathogenic factor is relatively mild, it blocks the pores and obstructs the normal flow of defensive Qi. This produces the classic exterior Cold symptoms of chills, mild fever, headache, and absence of sweating. Zi Su Ye, as the King herb, uses its warm acrid nature to open the pores and gently release the pathogen through mild sweating. Unlike stronger Wind-Cold formulas such as Ma Huang Tang, Xiang Su San uses a gentle approach suited to mild exterior presentations. The formula is especially appropriate when Wind-Cold occurs in someone who also has underlying Qi stagnation, a very common real-world scenario.

A practitioner would look for one or more of these signs

Chills

Aversion to cold, feeling chilly

Fever

Mild fever accompanying chills

Headaches

Headache from exterior Wind-Cold

Anhidrosis

Absence of sweating

Nasal Congestion

Stuffy nose

Commonly Prescribed For

These conditions can arise from the patterns above. A practitioner would consider Xiang Su San when these conditions are specifically caused by those patterns — not for all cases of these conditions.

TCM Interpretation

TCM views the common cold as an invasion of Wind-Cold or Wind-Heat through the body's surface defenses. This formula targets a specific subtype: Wind-Cold invasion in someone whose internal Qi is not flowing smoothly, often manifesting as a 'stomach flu' type cold. The exterior pathogen blocks the pores, causing chills and headache, while Qi stagnation in the Lung, Spleen, and Liver systems creates chest fullness, bloating, and poor appetite. TCM sees these as an interrelated problem: the external pathogen worsens the internal stagnation, and the internal stagnation makes it harder for the body to push out the pathogen.

Why Xiang Su San Helps

Xiang Su San addresses both the external and internal dimensions of this type of cold simultaneously. Zi Su Ye gently opens the pores to release the exterior Cold pathogen through mild sweating, while also helping move Qi in the chest and stomach. Xiang Fu powerfully unblocks Qi stagnation from the inside, restoring normal digestive movement. Chen Pi dries dampness and moves Qi in the Spleen and Stomach specifically, helping resolve bloating. Because the formula is mild and does not contain harsh sweating agents like Ma Huang, it is suitable for mild colds, elderly patients, children, pregnant women, and those with sensitive digestion.

Also commonly used for

Influenza

Mild influenza with chills, body aches, and digestive discomfort

Gastroesophageal Reflux Disease

Bile reflux gastritis with Qi stagnation pattern

Irritable Bowel Syndrome

IBS with prominent bloating and Qi stagnation features

Morning Sickness

Pregnancy-related nausea with concurrent Wind-Cold

Upper Respiratory Tract Infections

Mild upper respiratory infection with digestive involvement

What This Formula Does

Every TCM formula has a specific set of actions — here's what Xiang Su San does in the body, explained in both everyday and TCM terms

Therapeutic focus

In practical terms, Xiang Su San is primarily used to support these areas of health:

TCM Actions

In TCM terminology, these are the specific therapeutic actions that Xiang Su San performs to restore balance in the body:

How It Addresses the Root Cause

TCM doesn't just suppress symptoms — it aims to resolve the underlying imbalance. Here's how Xiang Su San works at the root level.

Xiang Su San addresses a very common clinical scenario: a person catches a cold (Wind-Cold invasion) while already having some degree of internal Qi stagnation. In TCM terms, Wind-Cold lodges on the body's surface, blocking the Lung's ability to open and close the pores properly. This produces chills, mild fever, headache, and an absence of sweating because the body's protective layer (Wei Qi) is constrained and cannot push the pathogen out.

At the same time, the patient has pre-existing or concurrent Qi stagnation in the chest and digestive system. This might come from emotional stress, irregular eating, or simply from the Cold pathogen itself impeding the smooth flow of Qi through the Lung and Stomach. When Qi cannot move freely in the Middle Burner (the digestive region), it produces a feeling of stuffiness and fullness in the chest and upper abdomen, poor appetite, and sometimes belching or nausea. The tongue coating is thin and white (reflecting Cold rather than Heat), and the pulse floats (reflecting an exterior pathogen).

The core disease logic is a dual problem: the exterior is blocked by Cold, and the interior is congested by stagnant Qi. Because neither problem is severe, a gentle approach works best. A harsh diaphoretic (sweat-inducing) formula would be excessive, while a purely Qi-moving formula would not address the surface Cold. The formula's genius lies in treating both problems simultaneously with mild, aromatic herbs that gently open the exterior and smoothly move interior Qi, allowing the body to recover its normal circulation without overexertion.

Formula Properties

Every formula has an inherent temperature, taste, and affinity for specific organs — these properties determine how it interacts with the body

Overall Temperature

Warm

Taste Profile

Predominantly acrid and aromatic with mild sweetness. The acrid taste disperses the exterior and moves Qi, the aromatic quality opens congestion, and the sweetness from Licorice harmonizes and protects the Stomach.

Channels Entered

Ingredients

4 herbs

The herbs that make up Xiang Su San, organized by their role in the prescription

King — Main ingredient driving the formula
Deputy — Assists and enhances the King
Assistant — Supports or moderates other herbs
Envoy — Directs the formula to its target
King — Main ingredient driving the formula
Zi Su Ye

Zi Su Ye

Perilla leaves

Dosage 6 - 12g
Temperature Warm
Taste Pungent
Organ Affinity Lungs, Spleen

Role in Xiang Su San

Releases the exterior and disperses Wind-Cold while simultaneously moving Qi in the chest and middle burner. This dual action of resolving the exterior pathogen and addressing internal Qi stagnation makes it the ideal lead herb for this formula's combined pathomechanism.
Deputy — Assists and enhances the King
Xiang Fu

Xiang Fu

Coco-grass rhizomes

Dosage 6 - 12g
Temperature Neutral
Taste Bitter, Pungent, Sweet
Organ Affinity Liver, Spleen, San Jiao (Triple Burner)
Preparation Dry-fried until fragrant with hairs removed (炒香去毛)

Role in Xiang Su San

A premier herb for moving stagnant Qi and relieving constraint, particularly in the Liver channel. It enhances the Qi-regulating action of the King herb and, when paired with Zi Su Ye, gains the ability to reach the exterior and upper body to help expel pathogenic factors.
Assistant — Supports or moderates other herbs
Chen Pi

Chen Pi

Tangerine peel

Dosage 3 - 6g
Temperature Warm
Taste Bitter, Pungent
Organ Affinity Lungs, Spleen

Role in Xiang Su San

Regulates Qi and dries Dampness in the middle burner, assisting the King and Deputy herbs in resolving Qi stagnation while also transforming turbid Dampness that contributes to the chest fullness and poor appetite.
Envoy — Directs the formula to its target
Gan Cao

Gan Cao

Liquorice

Dosage 1.5 - 3g
Temperature Neutral
Taste Sweet
Organ Affinity Heart, Lungs, Spleen, Stomach

Role in Xiang Su San

Tonifies the Spleen and harmonizes the middle burner, preventing the Qi-moving herbs from depleting Qi. Also harmonizes the actions of all the other herbs in the formula.

Why This Combination Works

How the herbs in Xiang Su San complement each other

Overall strategy

The formula simultaneously releases the exterior to expel Wind-Cold and regulates interior Qi to resolve stagnation, a dual approach that addresses the combined pathomechanism of external invasion with internal Qi constraint. By pairing exterior-releasing herbs with Qi-moving herbs, it ensures that neither the surface chill nor the digestive discomfort is neglected.

King herbs

Zi Su Ye (Perilla Leaf) serves as the King because it uniquely bridges both halves of the treatment strategy. Its warm, acrid nature opens the pores to release Wind-Cold from the exterior, while its aromatic quality moves Qi in the chest and Stomach to relieve the sense of fullness and poor appetite. No other single herb in this formula addresses both the external and internal aspects so directly.

Deputy herbs

Xiang Fu (Cyperus Rhizome) is the foremost Qi-regulating herb in the Chinese pharmacopoeia, capable of coursing through all twelve channels. It powerfully opens Qi constraint, especially in the Liver and middle burner. When combined with Zi Su Ye, its Qi-moving action is carried outward and upward to reach the skin and exterior, an effect described by Li Shizhen: when Xiang Fu is combined with Zi Su Ye, it can disperse pathogenic factors from the surface.

Assistant herbs

Chen Pi (Tangerine Peel) serves as a reinforcing assistant, strengthening the Qi-regulating action of the King and Deputy from a different angle. It specifically targets the Spleen and Stomach, drying dampness and promoting the smooth flow of Qi through the digestive system. This addresses the turbid dampness that contributes to chest fullness and loss of appetite.

Envoy herbs

Zhi Gan Cao (Honey-prepared Licorice) harmonizes the formula in two ways: it gently supports Spleen Qi to prevent the vigorous Qi-moving herbs from consuming the body's Qi, and it moderates the properties of the other herbs to ensure the formula acts gently. This is essential because the formula is intended for mild presentations and even pregnancy.

Notable synergies

The Zi Su Ye and Xiang Fu pairing is the heart of this formula. Each herb amplifies the other: Zi Su Ye gives Xiang Fu the ability to reach the exterior and upper body, while Xiang Fu deepens Zi Su Ye's Qi-regulating effect within the organs. Together they achieve a comprehensive regulation of Qi flow from the interior to the surface that neither could accomplish alone. The addition of Chen Pi creates a three-herb Qi-moving axis spanning the Lung, Liver, and Spleen, ensuring that stagnation is resolved across all three organ systems involved in this pattern.

How to Prepare

Traditional preparation instructions for Xiang Su San

The original method calls for grinding the herbs into a coarse powder. Take 9g per dose, add approximately 150ml of water, and decoct until reduced to about 100ml. Strain and drink hot, three times daily without regard to mealtimes. If ground into a fine powder instead, take 6g per dose with a pinch of salt dissolved in warm water.

In modern clinical practice, the formula is commonly prepared as a standard decoction (Tang): combine the herbs with approximately 400ml of water, bring to a boil, then simmer for 15-20 minutes. Strain and divide into two doses, taken warm after meals. Dosages should be proportionally reduced from the original bulk amounts.

Common Modifications

How practitioners adapt Xiang Su San for specific situations

Added
Cong Bai

2-3 stalks, to enhance sweating and release the exterior

Sheng Jiang

3-6g, to warm the exterior and assist sweating

Jing Jie

6-9g, to dispel Wind-Cold from the surface

When Wind-Cold symptoms dominate with strong chills, headache, and body aches, the base formula's exterior-releasing power needs reinforcement. Cong Bai, Sheng Jiang, and Jing Jie all enhance sweating and Wind-Cold dispersion.

Educational content — always consult a qualified healthcare provider or TCM practitioner before using any herbal formula.

Contraindications

Situations where Xiang Su San should not be used or requires extra caution

Avoid

Exterior patterns due to Wind-Heat (fever predominating over chills, sore throat, yellow nasal discharge). This formula is warm and dispersing, designed for Wind-Cold, and would worsen Wind-Heat conditions.

Avoid

Yin deficiency with Heat signs (night sweats, dry mouth, hot palms and soles, red tongue with little coating). The warm, acrid, and drying nature of the formula can further injure Yin fluids.

Caution

Qi deficiency with profuse sweating. The formula's diaphoretic and Qi-moving herbs can further deplete Qi and cause excessive sweating in already weakened patients.

Caution

Patients with Blood deficiency or general debility. The acrid and dispersing nature of the herbs may scatter what little Qi and Blood remain, worsening the weakness.

Caution

Exterior conditions with underlying Damp-Heat. While the formula addresses Qi stagnation, it does not clear Heat or drain Dampness and could aggravate Damp-Heat accumulation.

Special Populations

Important considerations for pregnancy, breastfeeding, and pediatric use

Pregnancy

Generally considered safe during pregnancy when used at standard dosages for appropriate indications. Zi Su Ye (Perilla Leaf) is traditionally regarded as a pregnancy-safe herb and is even used classically to calm a restless fetus and treat morning sickness (pregnancy nausea). Xiang Fu (Cyperus) is a Qi-regulating herb that moves Qi without strongly moving Blood. Gan Cao (Licorice) and Chen Pi (Tangerine Peel) are also considered safe. However, as with any herbal formula during pregnancy, it should only be taken under professional guidance and for the shortest necessary duration. The formula's mild diaphoretic action warrants caution in pregnant women who are already sweating or have Qi deficiency.

Breastfeeding

No specific safety concerns have been identified for breastfeeding mothers. The four herbs in this formula (Perilla Leaf, Cyperus, Tangerine Peel, Licorice) are all mild, commonly used substances without known toxic components that would raise concerns about transfer through breast milk. Zi Su Ye is widely consumed as a culinary herb and food ingredient throughout East Asia. However, as the formula is mildly warm and dispersing, prolonged use should be avoided to prevent any drying effect on fluids, which could theoretically affect milk production. Short-term use for an acute cold is not expected to pose problems. Professional guidance is always advisable.

Children

Xiang Su San is considered a gentle formula suitable for pediatric use. Its mild, aromatic nature and lack of harsh or toxic ingredients make it appropriate for children with Wind-Cold accompanied by digestive upset. Dosage should be reduced proportionally based on age: roughly one-third of the adult dose for children aged 3-6, one-half for children aged 7-12, and two-thirds for adolescents. The classical text "You Ke Jin Zhen" (幼科金针) records a modified version of Xiang Su San specifically for childhood vomiting, adding herbs like Chai Hu, Gui Zhi, and Fang Feng. For very young children (under 3), professional guidance is essential and the formula should only be administered in small, dilute doses. The taste is relatively pleasant due to the aromatic herbs, which aids compliance.

Drug Interactions

If you are taking pharmaceutical medications, be aware of these potential interactions with Xiang Su San

No major drug interactions are well-documented for this specific formula. However, the following considerations are worth noting based on the known pharmacology of the individual herbs:

  • Gan Cao (Glycyrrhiza/Licorice): Licorice root has the most interaction potential of any herb in this formula. It may interact with antihypertensive medications (by promoting sodium retention and potassium loss), corticosteroids (potentiating their effects), digoxin (hypokalemia increasing digoxin toxicity risk), and diuretics (compounding electrolyte imbalances). At the relatively low dose used in this formula (one-quarter of the total), these interactions are unlikely in short-term use but should be considered in patients on these medications.
  • Zi Su Ye (Perilla Leaf): Perilla leaf contains rosmarinic acid, which has mild anti-inflammatory and antiplatelet properties. Patients on anticoagulant or antiplatelet therapy (warfarin, aspirin, clopidogrel) should be monitored, though the clinical significance at standard doses is likely low.
  • General: As a diaphoretic formula, it may theoretically affect the absorption rate of concurrently administered oral medications by altering gastrointestinal motility. Separating doses by at least one hour is prudent.

Usage Guidance

Practical advice for getting the most out of Xiang Su San

Best time to take

Warm, 30 minutes after meals, three times daily. Take while the decoction is still hot to enhance the diaphoretic effect.

Typical duration

Acute use: 2-5 days, until exterior symptoms resolve. Not intended for long-term use in its original form.

Dietary advice

While taking this formula, avoid cold and raw foods (salads, iced drinks, raw fruit), greasy or heavy foods, and dairy products, as these can generate Dampness and impede the formula's ability to move Qi and disperse Cold. Light, warm, and easily digestible foods such as congee (rice porridge), clear soups, and lightly cooked vegetables are ideal. A small amount of fresh ginger or scallion in food can complement the formula's warming, exterior-releasing action. Avoid alcohol and spicy, excessively hot foods which could generate internal Heat and counteract the formula's gentle, balanced approach.

Xiang Su San originates from Tai Ping Hui Min He Ji Ju Fang (太平惠民和剂局方) Sòng dynasty, first published ~1078 CE, revised through 1151 CE

Classical Texts

Key passages from the classical Chinese medical texts that first described Xiang Su San and its clinical use

《太平惠民和剂局方》 (Tài Píng Huì Mín Hé Jì Jú Fāng), Volume 2:

「治四时瘟疫、伤寒。」
"Treats seasonal epidemic diseases and Cold Damage (Shang Han)."

This is the original source text indication, establishing Xiang Su San as a formula for externally contracted illness across all four seasons. The text further records a legendary anecdote: a white-haired elder passed this formula to a wealthy family, who prepared and distributed it during a great epidemic, curing all who fell ill in the city.

汪昂 (Wāng Áng),《医方集解》(Yī Fāng Jí Jiě), "Formulas for Exterior and Interior":

「此手太阴药也。紫苏疏表气而散外寒,香附行里气而消内壅,橘红能兼行表里以佐之……甘草和中,亦能解表为使也。」
"This is a formula for the Hand Tai Yin (Lung) channel. Perilla Leaf disperses exterior Qi and scatters external Cold; Cyperus moves interior Qi and resolves internal congestion; Tangerine Peel assists by acting on both the exterior and interior... Licorice harmonizes the Middle and also assists in resolving the exterior as the envoy."

Historical Context

How Xiang Su San evolved over the centuries — its origins, lineage, and place in the broader tradition of Chinese medicine

Xiang Su San originates from the Tai Ping Hui Min He Ji Ju Fang (太平惠民和剂局方), compiled by the Imperial Pharmacy of the Song Dynasty and published around 1107 CE, with revisions through the 12th century. This text was essentially a government-issued formulary, making standardized prescriptions available to the public. The original text records it simply for "seasonal epidemic diseases and Cold Damage" (si shi wen yi, shang han), positioning it as an all-season formula for common colds and mild febrile diseases.

A notable anecdote preserved in the classical text describes a white-haired elder who gave this formula to a wealthy family during a great epidemic. The family prepared and distributed it freely, curing all who fell ill in the city. When the epidemic demons confronted the family, the elder's reputation preceded him: the demons reportedly said, "This old man has already taught three others," and retreated. This story reflects the formula's reputation as a broadly effective, safe remedy for common epidemic illness.

Later physicians expanded the formula significantly. The Shi Yi De Xiao Fang (世医得效方) version added Cang Zhu (Atractylodes), fresh ginger, and scallion white to strengthen its ability to dispel Dampness. The Yi Xue Xin Wu (医学心悟) created Jia Wei Xiang Su San by adding Jing Jie, Qin Jiao, Fang Feng, Man Jing Zi, and Chuan Xiong to strengthen the exterior-releasing effect, making it suitable for more pronounced Wind-Cold with body aches. In modern times, the renowned physician Tian Delu (田德禄) of Beijing University of Chinese Medicine adapted the formula by replacing Su Ye (leaf) with Su Geng (stem) and adding Qi-regulating and phlegm-transforming herbs, shifting its focus from exterior-releasing to treating chronic stomach distension and functional dyspepsia.