Sang Xing Tang

Mulberry Leaf and Apricot Kernel Decoction · 桑杏汤

A gentle, cooling formula used for dry cough, sore throat, and thirst that develop when warm, dry autumn weather affects the lungs. It works by lightly dispersing the dryness-heat from the body's surface while moistening and soothing the lungs to restore lost fluids.

Origin Wen Bing Tiao Bian (温病条辨, Systematic Differentiation of Warm Diseases) by Wu Tang (Wu Jutong) — Qīng dynasty, 1798 CE
Composition 7 herbs
Sang Ye
King
Sang Ye
Xing Ren
King
Xing Ren
Dan Dou Chi
Deputy
Dan Dou Chi
Sha Ren
Deputy
Sha Ren
Li Pi
Deputy
Li Pi
Zhi Zi
Assistant
Zhi Zi
Zh
Assistant
Zhe Bei Mu
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Educational content Consult qualified TCM practitioners for diagnosis and treatment

Patterns Addressed

In TCM, symptoms don't appear randomly — they cluster into recognizable patterns of disharmony that reveal what's out of balance in the body. Sang Xing Tang is designed to correct these specific patterns.

Why Sang Xing Tang addresses this pattern

Warm-dryness (温燥) is a seasonal pathogenic factor most common in early autumn, when heat from summer lingers and the air becomes dry. When it invades the body, it targets the Lung first because the Lung is the most delicate organ and has a direct connection to the nose and throat. The warm component causes mild fever and a floating, rapid pulse. The dry component scorches Lung fluids, producing a dry cough with no sputum (or only small amounts of sticky sputum), a dry and sore throat, thirst, and dry nasal passages.

Sang Xing Tang addresses this pattern through its combination of light dispersal and gentle moistening. The King herbs (Sang Ye and Xing Ren) clear the warm-dryness from the Lung's exterior while restoring its descending function. The Deputies (Sha Shen, Li Pi, Dan Dou Chi) replenish lost fluids and help release the remaining surface pathogen. The Assistants (Zhi Zi Pi, Zhe Bei Mu) clear residual heat and resolve sticky phlegm. This formula is specifically designed for the early, mild stage of warm-dryness before it penetrates deeper into the body.

A practitioner would look for one or more of these signs

Dry Cough

Cough with no sputum, or only scanty sticky sputum

Dry Throat

Throat dryness and soreness

Thirst

Thirst with desire to drink

Dry Nose

Nasal dryness

Low Grade Fever

Mild fever, body not very hot

Headaches

Headache from exterior pathogen

Red Tongue

Red tongue with thin, white, dry coating

Commonly Prescribed For

These conditions can arise from the patterns above. A practitioner would consider Sang Xing Tang when these conditions are specifically caused by those patterns — not for all cases of these conditions.

Arises from: Warm-Dryness attacking the Lung

TCM Interpretation

In TCM, upper respiratory tract infections are understood as invasions by external pathogenic factors that first affect the Lung and the body's defensive (Wei) Qi. The specific pathogen varies by season and individual constitution. In autumn, when the climate shifts from hot and humid to warm and dry, the Lung is especially vulnerable because it is a "tender" organ that prefers moisture. Warm-dryness consumes the Lung's protective fluids, impairs its ability to disperse and descend Qi, and irritates the throat and airways. This produces the characteristic dry cough, sore throat, slight fever, and thirst.

Why Sang Xing Tang Helps

Sang Xing Tang is well suited for autumn-onset upper respiratory infections because its composition directly targets the Warm-Dryness mechanism. Sang Ye and Dan Dou Chi gently release the exterior pathogen without causing heavy sweating that would further deplete fluids. Xing Ren restores the Lung's descending function to stop cough. Sha Shen and Li Pi replenish the fluids that the dryness-heat has consumed, addressing thirst and throat dryness at their root. Zhi Zi Pi clears lingering heat from the upper body, while Zhe Bei Mu helps resolve any sticky phlegm. The formula's deliberately light dosages match the mild, early-stage nature of most uncomplicated upper respiratory infections.

Also commonly used for

Chronic Bronchitis

Acute exacerbation with warm-dryness features

Bronchiectasis

When accompanied by hemoptysis from dryness-heat scorching Lung vessels

Whooping Cough

Pertussis with dry cough pattern

Pharyngitis

Dry, sore throat from warm-dryness

Dry Cough

Persistent dry cough during autumn season

Asthma

When dry cough is the dominant symptom with warm-dryness signs

What This Formula Does

Every TCM formula has a specific set of actions — here's what Sang Xing Tang does in the body, explained in both everyday and TCM terms

Therapeutic focus

In practical terms, Sang Xing Tang is primarily used to support these areas of health:

TCM Actions

In TCM terminology, these are the specific therapeutic actions that Sang Xing Tang performs to restore balance in the body:

How It Addresses the Root Cause

TCM doesn't just suppress symptoms — it aims to resolve the underlying imbalance. Here's how Sang Xing Tang works at the root level.

Sang Xing Tang addresses a specific situation that arises in autumn: the Lungs are attacked by warm, dry climatic Qi (温燥). In TCM, the Lungs are considered a "delicate organ" (娇脏) that prefers moisture and is easily damaged by dryness. When warm Dryness invades from the outside, it first strikes the Lung's protective (Wei) level and the Qi aspect of the Lung channel.

The warm Dryness dries up the Lung's fluids. This is why the person develops a dry, irritating cough with no phlegm or only scant, sticky phlegm that is difficult to expectorate. The throat and nose become parched because the Lung governs the nose and connects to the throat, and its moistening function has been impaired. Mild fever and slight headache occur because the body's defensive Qi is struggling against the invading pathogen at the surface. The tongue appears red with a thin, dry, white coating, and the pulse is floating and rapid (especially large on the right side, which reflects the Lung), all confirming that Heat and Dryness are consuming Lung fluids at a superficial level.

Crucially, this is a mild, early-stage condition. The dryness has not yet penetrated deeply or severely depleted the body's Yin. The treatment strategy must therefore be light and gentle: gently disperse the exterior Dryness-Heat while simultaneously moistening and protecting the Lung fluids. Overly strong or heavy medicines would "overshoot the disease location," as Wu Jutong cautioned.

Formula Properties

Every formula has an inherent temperature, taste, and affinity for specific organs — these properties determine how it interacts with the body

Overall Temperature

Slightly Cool

Taste Profile

Predominantly acrid (pungent) and sweet with a mild bitter note. The acrid quality gently disperses the exterior pathogen, the sweet taste moistens and nourishes Lung fluids, and the slight bitterness clears Heat.

Target Organs

Channels Entered

Ingredients

7 herbs

The herbs that make up Sang Xing Tang, organized by their role in the prescription

King — Main ingredient driving the formula
Deputy — Assists and enhances the King
Assistant — Supports or moderates other herbs
Kings — Main ingredient driving the formula
Sang Ye

Sang Ye

Mulberry leaf

Dosage 3g
Temperature Cold
Taste Sweet (甘 gān), Bitter (苦 kǔ)
Organ Affinity Lungs, Liver

Role in Sang Xing Tang

Light, cool, and aromatic, Sang Ye gently disperses warm-dryness from the Lung and Wei (defensive) level. Its acrid-cool nature releases the exterior pathogen without being overly cold or harsh, making it ideal for a mild warm-dryness presentation.
Xing Ren

Xing Ren

Bitter apricot kernel

Dosage 4.5g
Temperature Slightly Warm
Taste Bitter (苦 kǔ)
Organ Affinity Lungs, Large Intestine

Role in Sang Xing Tang

Descends and regulates Lung Qi to stop cough while gently moistening dryness. Partners with Sang Ye to address both the exterior pathogen (through dispersal) and the interior symptom (cough from impaired Lung descending function).
Deputies — Assists and enhances the King
Dan Dou Chi

Dan Dou Chi

Fermented soybean

Dosage 3g
Temperature Cool
Taste Bitter (苦 kǔ), Acrid / Pungent (辛 xīn)
Organ Affinity Lungs, Stomach

Role in Sang Xing Tang

Assists Sang Ye in gently releasing the exterior by dispersing mild heat from the surface and upper body. Its light, dispersing nature helps vent pathogens outward without damaging fluids.
Sha Ren

Sha Ren

Amomum fruit

Dosage 6g
Temperature Warm
Taste Acrid / Pungent (辛 xīn), Aromatic (芳香 fāng xiāng)
Organ Affinity Spleen, Stomach, Kidneys

Role in Sang Xing Tang

Nourishes Lung Yin and generates fluids. As the herb with the largest dosage in the formula, it counterbalances the drying tendency of the pathogen by replenishing the fluids that warm-dryness has begun to consume.
Li Pi

Li Pi

Pear skin

Dosage 3g
Temperature Cool
Taste Sweet (甘 gān), Astringent (涩 sè)
Organ Affinity Lungs, Heart, Kidneys, Large Intestine

Role in Sang Xing Tang

Cool and sweet, it clears heat and moistens dryness in the Lung. Works alongside Sha Shen to generate fluids and soothe the dry, irritated respiratory tract.
Assistants — Supports or moderates other herbs
Zhi Zi

Zhi Zi

Gardenia fruit

Dosage 3g
Temperature Cold
Taste Bitter (苦 kǔ)
Organ Affinity Heart, Lungs, San Jiao (Triple Burner)

Role in Sang Xing Tang

The peel of Gardenia fruit is light and directed upward, specifically clearing heat from the Upper Jiao (upper body) and the Lung. Using only the peel rather than the whole fruit keeps the action light and focused on the superficial level of the disease.
Zh

Zhe Bei Mu

Zhejiang Fritillary bulb

Dosage 3g
Temperature Cold
Taste Bitter (苦 kǔ)
Organ Affinity Heart, Lungs

Role in Sang Xing Tang

Clears heat and transforms phlegm to help resolve any sticky, scanty sputum caused by the drying and heating of Lung fluids. Assists Xing Ren in stopping cough by addressing the phlegm component.

Why This Combination Works

How the herbs in Sang Xing Tang complement each other

Overall strategy

Warm-dryness has invaded the Lung and defensive Qi level, scorching Lung fluids and impairing the Lung's descending function. The formula uses a strategy the original text describes as "acrid-cool, sweet, and moistening" (辛凉甘润) to gently clear warm-dryness from the exterior while simultaneously moistening the Lung and restoring fluids internally.

King herbs

Sang Ye (Mulberry Leaf) and Xing Ren (Apricot Kernel) together form the core of the formula. Sang Ye is light, acrid, and cool, and it excels at dispersing warm-dryness from the Lung and surface level without being overly harsh. Xing Ren descends Lung Qi and moistens dryness, directly addressing the dry cough that is the hallmark symptom. Together, one disperses outward and upward while the other directs downward, restoring the Lung's natural rhythm of dispersing and descending.

Deputy herbs

Dan Dou Chi (Prepared Soybean) is acrid and mildly cool, reinforcing Sang Ye's ability to release the exterior and vent mild heat from the chest and surface. Sha Shen (Adenophora Root) and Li Pi (Pear Skin) are sweet and cool, nourishing Yin and generating fluids to replenish what warm-dryness has consumed. Sha Shen carries the highest dosage in the formula (6g versus 3g for most others), reflecting the importance of protecting Lung fluids in this pattern.

Assistant herbs

Zhi Zi Pi (Gardenia Peel) is a restraining assistant that specifically clears residual heat from the Upper Jiao and the Lung. Only the peel is used because it is lighter and more superficially directed than the whole fruit, matching the mild, surface-level nature of the disease. Zhe Bei Mu (Thunberg Fritillaria) is a reinforcing assistant that clears heat-phlegm and stops cough, addressing the scanty, sticky sputum that arises when Lung fluids are partially dried and thickened by warmth.

Notable synergies

Sang Ye paired with Dan Dou Chi creates a synergy for gentle exterior-releasing: one disperses from the Lung level while the other vents from the surface, together clearing the pathogen without strong diaphoresis that would further damage fluids. Sha Shen paired with Li Pi provides dual moistening and fluid-generating action, ensuring the Lung is nourished from within even as the formula clears the pathogen from without. The entire formula demonstrates a key principle: all dosages are kept deliberately light because the pathogen is mild and superficial, and heavy doses would "overshoot the site of disease."

How to Prepare

Traditional preparation instructions for Sang Xing Tang

Using the original classical method: add two cups of water (approximately 400 mL), bring to a boil and simmer until reduced to one cup (approximately 200 mL). Strain and drink the entire dose in one sitting. In more severe cases, prepare and take a second dose the same day. This formula represents a single serving dose, and may be taken 1 to 2 times per day.

The original text specifically notes: "Light medicinals must not be used in heavy doses; heavy doses will overshoot the site of disease" (轻药不得重用,重用必过病所). All herb dosages in this formula are deliberately light, and the decoction should not be boiled for too long, as prolonged cooking would diminish the light, dispersing quality of the herbs.

Modern usage: Dosages are often increased 2 to 3 times from the original amounts. Prepare as a standard water decoction (水煎服).

Common Modifications

How practitioners adapt Sang Xing Tang for specific situations

Added
Shi Gao

15 - 30g, clears intense heat from the Lung and Stomach

Zhi Mu

6 - 9g, clears heat and nourishes Yin

When warm-dryness generates more intense heat than the base formula can manage, Shi Gao and Zhi Mu powerfully clear Lung heat while Zhi Mu simultaneously protects fluids, preventing the stronger heat-clearing from further damaging Yin.

Educational content — always consult a qualified healthcare provider or TCM practitioner before using any herbal formula.

Contraindications

Situations where Sang Xing Tang should not be used or requires extra caution

Avoid

Cool Dryness (凉燥) patterns: This formula is designed for warm Dryness only. Cool Dryness presents with chills, thin white tongue coating, and watery phlegm, and requires warming, dispersing formulas such as Xing Su San instead.

Avoid

Wind-Cold exterior patterns with pronounced chills, body aches, and absence of thirst or dryness symptoms. The cooling and moistening nature of this formula would worsen a Cold pattern.

Caution

Cold-Dampness or Spleen-Stomach deficiency with Cold: The formula's cool, moistening herbs may aggravate Dampness or weaken digestive function in patients with loose stools, poor appetite, or a thick greasy tongue coating.

Caution

Severe Yin Deficiency with empty Heat: This formula treats a mild, early-stage exterior Dryness condition. Deep-seated Yin Deficiency with significant internal Heat requires heavier nourishing formulas like Qing Zao Jiu Fei Tang or Sha Shen Mai Dong Tang.

Caution

Productive cough with copious, thin, white phlegm, indicating Phlegm-Dampness rather than Dryness. The moistening herbs would further increase Phlegm production.

Special Populations

Important considerations for pregnancy, breastfeeding, and pediatric use

Pregnancy

Generally considered safe for short-term use during pregnancy, but caution is warranted. Xing Ren (Apricot Kernel) contains amygdalin, which can be toxic in large doses; however, the dosages in this formula are very light (3-4.5g). Dan Dou Chi (Fermented Soybean) has mild dispersing properties that are unlikely to cause concern at these small doses. Pregnant women should consult a qualified practitioner before use, and the formula should not be taken for extended periods.

Breastfeeding

No specific contraindications for breastfeeding have been documented for Sang Xing Tang. The herbs are mild in nature and used at very light dosages. Sang Ye (Mulberry Leaf), Sha Shen (Adenophora Root), and Li Pi (Pear Peel) are food-grade or commonly consumed substances. Xing Ren (Apricot Kernel) contains trace amygdalin, but at the formula's low doses, transfer through breast milk is unlikely to be clinically significant. As with any herbal formula during breastfeeding, use should be supervised by a qualified practitioner and limited to the shortest effective course.

Children

Sang Xing Tang can be used in children with appropriate dosage reduction. General pediatric dosing guidelines apply: - Infants under 1 year: not typically recommended without specialist supervision. - Children 1-5 years: approximately one-third of the adult dose. - Children 6-12 years: approximately one-half to two-thirds of the adult dose. - Adolescents over 12: near-adult doses may be appropriate. The formula's gentle nature and light dosages make it well-suited for pediatric respiratory conditions presenting with dry cough and mild fever in autumn. Xing Ren (Apricot Kernel) should be carefully dosed in young children due to amygdalin content. The decoction can be sweetened slightly with honey (for children over 1 year) to improve palatability.

Drug Interactions

If you are taking pharmaceutical medications, be aware of these potential interactions with Sang Xing Tang

No major drug interactions have been specifically documented for Sang Xing Tang in clinical literature. However, the following theoretical considerations apply based on the pharmacological properties of individual herbs:

  • Xing Ren (Apricot Kernel): Contains amygdalin, which is metabolized to trace amounts of hydrogen cyanide. Caution is advised with concurrent use of other cyanogenic compounds or in patients taking high-dose vitamin C supplements (which may theoretically increase cyanide conversion).
  • Zhi Zi Pi (Gardenia Peel): Gardenia fruit has been shown to have mild effects on bilirubin metabolism and liver enzymes. Patients taking hepatically-metabolized medications should be monitored.
  • Anticoagulant or antiplatelet drugs: Sang Ye (Mulberry Leaf) has mild blood-sugar and blood-lipid modulating properties. While clinically unlikely to be significant at these low doses, patients on antidiabetic medications or blood thinners should inform their practitioner.

Overall, given the very light dosages used in this formula and its intended short-term use, clinically significant drug interactions are unlikely but not impossible.

Usage Guidance

Practical advice for getting the most out of Sang Xing Tang

Best time to take

Taken warm, 30 minutes after meals, 1-2 times daily. The original text specifies taking the full decoction in one dose (顿服), with a repeat dose for more severe cases.

Typical duration

Acute use: 3-7 days. As a formula for mild, early-stage exterior Dryness, it is intended for short courses and should be reassessed promptly if symptoms do not improve or worsen.

Dietary advice

While taking this formula, favor foods that moisten the Lungs and generate fluids: pears, white fungus (Bai Mu Er), lily bulb (Bai He), honey, sesame, and congee. Drink adequate warm fluids throughout the day. Avoid foods that intensify Dryness or generate Heat: deep-fried and greasy foods, spicy or heavily seasoned dishes (chili, pepper, ginger), roasted nuts, alcohol, and strong coffee. Also avoid cold or raw foods that may impair the Spleen's fluid distribution, as well as dairy products which may thicken phlegm.

Sang Xing Tang originates from Wen Bing Tiao Bian (温病条辨, Systematic Differentiation of Warm Diseases) by Wu Tang (Wu Jutong) Qīng dynasty, 1798 CE

Classical Texts

Key passages from the classical Chinese medical texts that first described Sang Xing Tang and its clinical use

Wu Jutong (吴鞠通), Wen Bing Tiao Bian (《温病条辨》), Volume 1, Upper Burner Chapter, Article 54:

「秋感燥气,右脉数大,伤手太阴气分者,桑杏汤主之。」

"When autumn Dryness is contracted, with a rapid and large pulse on the right wrist, injuring the Qi aspect of the hand Tai Yin [Lung] channel, Sang Xing Tang governs."

Commentary following the article:

「其由于本气自病之燥证,初起必在肺卫,故以桑杏汤清气分之燥也。」

"Dryness conditions arising from the seasonal Qi itself always begin in the Lung and the defensive level, therefore Sang Xing Tang is used to clear Dryness from the Qi aspect."

Formula method note (方后注):

「轻药不得重用,重用必过病所。」

"Light medicines must not be used in heavy doses; heavy doses will overshoot the disease location."

Historical Context

How Sang Xing Tang evolved over the centuries — its origins, lineage, and place in the broader tradition of Chinese medicine

Sang Xing Tang was created by Wu Jutong (吴鞠通, 1758-1836), one of the four great masters of the Warm Disease (Wen Bing) school during the Qing Dynasty. It appears in his landmark work Wen Bing Tiao Bian (《温病条辨》, Systematic Differentiation of Warm Diseases), published in 1798, within the Upper Burner chapter under the section on Autumn Dryness (秋燥).

Wu Jutong's creation of this formula was historically significant because it addressed a gap in classical medicine. He noted that earlier physicians had claimed "of the six climatic factors, only Dryness does not cause disease" (六气之中,惟燥不为病). Wu argued this was mistaken, pointing out that the Huang Di Nei Jing simply lacked a dedicated discussion of autumnal Dryness, leading to this erroneous conclusion. By establishing Sang Xing Tang as the representative formula for warm Dryness, Wu gave clinicians a clear treatment framework for this previously underrecognized pattern. The formula exemplifies Wu's therapeutic philosophy of using the lightest possible intervention for superficial conditions, captured in his famous instruction: "light medicines must not be used heavily; heavy doses will overshoot the disease location."

The formula also helped clarify the distinction between warm Dryness (温燥) and cool Dryness (凉燥), with Sang Xing Tang treating the former and Xing Su San treating the latter. This differentiation became a cornerstone of Dryness pattern diagnosis in later TCM education.

Modern Research

A published study investigating the pharmacological effects or clinical outcomes of Sang Xing Tang

1

Combined exploration of the mechanism of Sang Xing Decoction in the treatment of smoke-induced acute bronchitis from protein and metabolic levels (Animal study, 2022)

Wang J, et al. Biomedicine & Pharmacotherapy. 2022; 152: 113236.

This preclinical study used network pharmacology, metabolomics, and a rat model of smoke-induced acute bronchitis to investigate how Sang Xing Tang works at a molecular level. The researchers identified 50 active compounds and 45 key protein targets. They found that the formula may reduce lung inflammation by regulating the PI3K/Akt/NF-kB signaling pathway, improving glutamine and glutamate metabolism to reduce oxidative stress, and inhibiting programmed cell death in lung tissue.

PubMed

Research on TCM formulas is growing but still limited by Western clinical trial standards. These studies provide emerging evidence and should be considered alongside practitioner expertise.