Formula Pill (Wan)

Bi Yan Wan

Nose Inflammation Pills · 鼻炎丸

Also known as: Bi Yan Pian (鼻炎片), Nose Inflammation Tablets, Cool Sinus Teapills,

A widely used Chinese herbal formula for relieving nasal congestion, sinus pressure, runny nose, and headaches caused by colds, allergies, or sinusitis. It works by dispersing Wind from the head, clearing Heat and inflammation in the nasal passages, and opening the sinuses to restore comfortable breathing.

Origin Modern formula derived from Cāng Ěr Zǐ Sǎn (苍耳子散) of Jì Shēng Fāng (济生方) by Yán Yòng-Hé (严用和) — Modern formulation (based on Sòng dynasty source, 1253 CE)
Composition 12 herbs
Cang Er Zi
King
Cang Er Zi
Xin Yi Hua
King
Xin Yi Hua
Lian Qiao
Deputy
Lian Qiao
Huang Qi
Deputy
Huang Qi
Bai Zhi
Assistant
Bai Zhi
Jing Jie
Assistant
Jing Jie
Fang Feng
Assistant
Fang Feng
Ye Ju Hua
Assistant
Ye Ju Hua
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Educational content Consult qualified TCM practitioners for diagnosis and treatment

Patterns Addressed

In TCM, symptoms don't appear randomly — they cluster into recognizable patterns of disharmony that reveal what's out of balance in the body. Bi Yan Wan is designed to correct these specific patterns.

Why Bi Yan Wan addresses this pattern

When Wind-Heat invades the Lung system, it rises to the head and obstructs the nasal passages, causing congestion, thick yellow discharge, headache, and sometimes fever. The Lung's normal function of dispersing and descending Qi to the nose is impaired. Bi Yan Wan directly addresses this by using Cang Er Zi and Xin Yi Hua to open the blocked orifices, Lian Qiao and Ye Ju Hua to clear the Wind-Heat and resolve toxins, and Huang Bai to drain any Damp-Heat that has settled in. Jing Jie and Fang Feng release the pathogenic Wind from the Exterior, while Zhi Mu clears residual Heat and prevents drying. This makes the formula particularly well suited for nasal congestion with signs of Heat such as yellow or green discharge, red and swollen nasal membranes, and sore throat.

A practitioner would look for one or more of these signs

Nasal Congestion

Stuffy nose with thick yellow or green discharge

Headaches

Frontal or sinus headache with pressure

Sore Throat

Mild sore or dry throat

Red Eyes

Red, itchy, or watery eyes

Sneezing

Frequent sneezing

Fever

Low-grade fever or sensation of heat

Commonly Prescribed For

These conditions can arise from the patterns above. A practitioner would consider Bi Yan Wan when these conditions are specifically caused by those patterns — not for all cases of these conditions.

TCM Interpretation

In TCM, allergic rhinitis (called bi qiu 鼻鼽) is understood as a condition where the Lung's defensive Qi (Wei Qi) is insufficient to protect the nose from external Wind. When Wind carries pathogenic factors (Cold, Heat, or Dampness) into the nasal passages, it disrupts the Lung's control over the nose, an orifice directly connected to the Lung organ system. The nose becomes congested, secretions overflow, and sneezing results from the body's attempt to expel the invader. The recurrent nature of allergic rhinitis often points to underlying Lung Qi or Spleen Qi deficiency, which leaves the person vulnerable to repeated invasions. The immediate episode, however, presents as an acute Wind pattern with nasal obstruction.

Why Bi Yan Wan Helps

Bi Yan Wan directly targets the acute presentation of allergic rhinitis. Cang Er Zi and Xin Yi Hua open the congested nasal passages and have demonstrated antihistamine-like properties in modern research. Jing Jie and Fang Feng dispel the Wind pathogen and reduce allergic itching. Wu Wei Zi astringes Lung Qi to curb the runny nose and excessive sneezing. Ye Ju Hua clears Heat and soothes itchy, red eyes. This formula is primarily aimed at symptomatic relief during acute flare-ups. For patients with chronic, recurrent allergic rhinitis, practitioners often combine or alternate Bi Yan Wan with a Qi-tonifying formula like Yu Ping Feng San to strengthen the body's defenses against future attacks.

Also commonly used for

Nasal Congestion

Stuffy nose from colds, allergies, or chronic rhinitis

Headaches

Sinus headache or frontal headache associated with nasal congestion

Hay Fever

Seasonal hay fever with sneezing, runny nose, and itchy eyes

What This Formula Does

Every TCM formula has a specific set of actions — here's what Bi Yan Wan does in the body, explained in both everyday and TCM terms

Therapeutic focus

In practical terms, Bi Yan Wan is primarily used to support these areas of health:

TCM Actions

In TCM terminology, these are the specific therapeutic actions that Bi Yan Wan performs to restore balance in the body:

How It Addresses the Root Cause

TCM doesn't just suppress symptoms — it aims to resolve the underlying imbalance. Here's how Bi Yan Wan works at the root level.

The nose is the opening of the Lungs. When the Lungs are functioning well, their Qi disperses and descends smoothly, keeping the nasal passages clear and moist. Bi Yan Wan addresses what happens when this system breaks down due to external invasion combined with internal Heat.

The typical scenario begins when Wind, often carrying Heat, invades through the nose and skin. This external Wind disrupts the Lung Qi's normal dispersing and descending function, causing it to stagnate in the nasal passages. The blocked Qi leads to nasal congestion. Meanwhile, the Heat component thickens nasal fluids into sticky, discolored mucus. In TCM terms, the turbid Yin that should descend and be cleared instead accumulates and rises upward into the head, causing headache and a heavy, foggy feeling. The retained pathogenic factors can also congeal fluids into Phlegm, which further obstructs the nasal orifices and sinuses.

In chronic or recurring cases, lingering Heat may also involve Dampness. Damp-Heat is sticky and hard to resolve, which is why sinus conditions can drag on for weeks or months. The Stomach channel (which passes through the face and nose) and the Gallbladder channel are also implicated, as classical teaching notes that "when the Gallbladder transfers Heat to the Brain, the result is nasal discharge" (胆移热于脑则辛頞鼻渊). Thus the condition involves the Lungs losing their dispersing role on the surface, while accumulated Heat and Dampness congest the head region from within.

Formula Properties

Every formula has an inherent temperature, taste, and affinity for specific organs — these properties determine how it interacts with the body

Overall Temperature

Slightly Cool

Taste Profile

Predominantly acrid (pungent) and bitter, with the acrid taste to disperse Wind and open orifices, and the bitter taste to clear Heat, drain Dampness, and direct turbidity downward.

Channels Entered

Ingredients

12 herbs

The herbs that make up Bi Yan Wan, organized by their role in the prescription

King — Main ingredient driving the formula
Deputy — Assists and enhances the King
Assistant — Supports or moderates other herbs
Envoy — Directs the formula to its target
Kings — Main ingredient driving the formula
Cang Er Zi

Cang Er Zi

Cocklebur fruits

Dosage 6 - 9g
Temperature Warm
Taste Bitter, Sweet
Organ Affinity Lungs

Role in Bi Yan Wan

The primary herb for opening the nasal passages, dispersing Wind, eliminating Dampness, and relieving sinus pain. It ascends to the head and directly targets nasal obstruction.
Xin Yi Hua

Xin Yi Hua

Biond’s magnolia flowers

Dosage 6 - 9g
Temperature Warm
Taste Pungent
Organ Affinity Stomach, Lungs
Preparation Wrap in cloth (包煎) when decocting to prevent fine hairs from irritating the throat

Role in Bi Yan Wan

The quintessential herb for nasal congestion. Its warm, aromatic nature disperses Wind-Cold from the head and unblocks the nasal orifices. Together with Cang Er Zi, it forms the core pair for treating nasal disease.
Deputies — Assists and enhances the King
Lian Qiao

Lian Qiao

Forsythia fruits

Dosage 6 - 9g
Temperature Cool
Taste Bitter
Organ Affinity Heart, Lungs, Small Intestine

Role in Bi Yan Wan

Clears Heat and resolves toxins, reduces swelling and inflammation in the nasal passages and sinuses. Addresses the Wind-Heat component and prevents infection.
Huang Qi

Huang Qi

Milkvetch roots

Dosage 3 - 6g
Temperature Warm
Taste Sweet
Organ Affinity Lungs, Spleen

Role in Bi Yan Wan

Drains Damp-Heat, clears toxic Heat, and dries Dampness. Particularly effective for yellow, thick, purulent nasal discharge indicating Heat and infection in the sinuses.
Assistants — Supports or moderates other herbs
Bai Zhi

Bai Zhi

Angelica roots

Dosage 3 - 6g
Temperature Warm
Taste Pungent
Organ Affinity Spleen, Stomach, Lungs

Role in Bi Yan Wan

Releases the Exterior, expels Wind, opens the nasal passages, dries Dampness, and alleviates frontal headache and supraorbital pain. It enters the Yangming channel and strongly targets the face and nose.
Jing Jie

Jing Jie

Japanese catnip

Dosage 3 - 6g
Temperature Neutral
Taste Pungent
Organ Affinity Liver, Lungs

Role in Bi Yan Wan

Disperses Wind from the Exterior, opens the nasal sinuses, and relieves itching. Versatile for both Wind-Cold and Wind-Heat patterns when combined with appropriate herbs.
Fang Feng

Fang Feng

Saposhnikovia roots

Dosage 3 - 6g
Temperature Warm
Taste Pungent, Sweet
Organ Affinity Urinary Bladder, Liver, Spleen

Role in Bi Yan Wan

Expels Wind and relieves head and facial pain. Works gently to support the surface-releasing herbs and alleviates congestion without being overly drying.
Ye Ju Hua

Ye Ju Hua

Wild chrysanthemum flower

Dosage 3 - 6g
Temperature Cool
Taste Bitter, Pungent
Organ Affinity Lungs, Liver

Role in Bi Yan Wan

Clears Wind-Heat, clears Heat toxins, and benefits the eyes. Addresses red, itchy, watery eyes that often accompany nasal allergies and sinusitis.
Zhi Mu

Zhi Mu

Anemarrhena rhizomes

Dosage 3 - 6g
Temperature Cold
Taste Bitter, Sweet
Organ Affinity Kidneys, Lungs, Stomach

Role in Bi Yan Wan

Clears Heat and nourishes Yin, soothes hot and irritated nasal membranes, and prevents the warm, drying herbs in the formula from depleting fluids. Balances the formula's overall drying tendency.
Wu Wei Zi

Wu Wei Zi

Schisandra berries

Dosage 3 - 6g
Temperature Warm
Taste Sour, Sweet
Organ Affinity Heart, Kidneys, Lungs

Role in Bi Yan Wan

An astringent herb that consolidates Lung Qi and restrains excessive nasal secretions. Prevents the dispersing herbs from over-releasing, helping to stop runny nose and excessive sneezing.
Envoys — Directs the formula to its target
Jie Geng

Jie Geng

Platycodon roots

Dosage 3 - 6g
Temperature Neutral
Taste Bitter, Pungent
Organ Affinity Lungs

Role in Bi Yan Wan

Opens and disseminates Lung Qi, transforms Phlegm, benefits the throat, and serves as a guide herb that directs the formula's actions upward to the head and nasal passages.
Gan Cao

Gan Cao

Liquorice

Dosage 3 - 6g
Temperature Neutral
Taste Sweet
Organ Affinity Heart, Lungs, Spleen, Stomach

Role in Bi Yan Wan

Harmonizes all the herbs in the formula, clears Heat in the Middle Burner, supplements Qi, and moderates the harsh or toxic properties of some ingredients such as Cang Er Zi.

Why This Combination Works

How the herbs in Bi Yan Wan complement each other

Overall strategy

Bi Yan Wan addresses nasal congestion and sinus inflammation caused by external Wind invading the Lung system and blocking the nasal orifices. The formula employs a multi-layered approach: aromatic herbs open the nose, Wind-dispersing herbs release the pathogen from the surface, Heat-clearing herbs address inflammation and infection, and astringent and Yin-nourishing herbs prevent the drying dispersal from going too far.

King herbs

Cang Er Zi and Xin Yi Hua are the core pair (known in classical tradition as the premier combination for nasal disease). Cang Er Zi ascends to the head, disperses Wind-Dampness, and unblocks the nasal passages with particular strength against thick, turbid discharge. Xin Yi Hua is the single most important herb in TCM for nasal congestion, using its warm, aromatic nature to open the orifices and dispel Wind-Cold from the sinuses. Together they directly target the primary complaint.

Deputy herbs

Lian Qiao clears externally contracted Wind-Heat, resolves toxins, and reduces swelling in the nasal and sinus tissues. Huang Bai drains Damp-Heat and clears residual toxic Heat, particularly addressing yellow-green purulent discharge that signals deeper infection. These two ensure the formula can handle the Heat component, whether from an initial Wind-Heat invasion or from prolonged congestion transforming into Heat.

Assistant herbs

Bai Zhi (reinforcing) targets the Yangming channels of the face, strongly opening the nose and relieving frontal and supraorbital headache. Jing Jie and Fang Feng (reinforcing) form a classic Wind-expelling trio that broadens the formula's effectiveness against both Wind-Cold and Wind-Heat presentations. Ye Ju Hua (reinforcing) clears Wind-Heat and Heat-toxins, particularly benefiting red or itchy eyes. Zhi Mu (restraining) clears internal Heat, nourishes Yin, and moistens the membranes, preventing the many warm, drying, aromatic herbs from damaging nasal fluids and causing excessive dryness. Wu Wei Zi (restraining) astringes Lung Qi to stop excessive nasal discharge and sneezing, counterbalancing the strongly dispersing nature of the King and other surface-releasing herbs.

Envoy herbs

Jie Geng opens and lifts Lung Qi, guiding all the other herbs upward to the head and nasal region where they are needed. Gan Cao harmonizes the formula, moderates the toxicity of Cang Er Zi, and supports the middle, ensuring the many pungent and bitter herbs do not damage the Stomach.

Notable synergies

The Cang Er Zi and Xin Yi Hua pairing is one of the most celebrated herb combinations in TCM rhinology, each reinforcing the other's ability to open the nose. Jing Jie paired with Fang Feng creates a gentle but effective Wind-expelling combination that works across Cold and Heat patterns. The balance between dispersing herbs (Cang Er Zi, Xin Yi Hua, Bai Zhi, Jing Jie, Fang Feng) and restraining/moistening herbs (Wu Wei Zi, Zhi Mu) is what makes this formula safe for extended use without excessive drying.

How to Prepare

Traditional preparation instructions for Bi Yan Wan

Bi Yan Wan is typically prepared as a patent medicine in pill or tablet form. The crude herbs are dried and ground into fine powder. An extract of Jie Geng (Platycodon root) and Jing Jie (Schizonepeta) is prepared separately and added to the powder mixture. The combined material is then formed into small pills (teapills) or compressed tablets, often with a thin sugar or film coating.

Standard dosage: 4 pills or tablets, taken 3 times daily with warm water. For decoction use, the herbs may be simmered in 3 cups of water for 20-30 minutes, strained, and taken in two divided doses daily. Xin Yi Hua (Magnolia flower) should be wrapped in cloth (包煎, bāo jiān) when making a decoction to prevent its fine hairs from irritating the throat.

Common Modifications

How practitioners adapt Bi Yan Wan for specific situations

Added
Xi Xin

1-3g, strongly opens nasal orifices and disperses deep Cold

E Bu Shi Cao

6-9g, a key herb for restoring the sense of smell and clearing nasal obstruction

Xi Xin and E Bu Shi Cao are two of the strongest nasal-opening herbs in the materia medica, added when the standard formula is insufficient to break through severe nasal blockage.

Educational content — always consult a qualified healthcare provider or TCM practitioner before using any herbal formula.

Contraindications

Situations where Bi Yan Wan should not be used or requires extra caution

Caution

Nasal conditions due to pure Qi deficiency or Yang deficiency without external pathogenic factors. The formula's dispersing and cooling nature may further weaken a constitutionally depleted patient. In such cases, formulas that tonify Qi and warm Yang (such as Yu Ping Feng San or Bu Zhong Yi Qi Tang) are more appropriate.

Avoid

Pregnancy, due to the presence of Cang Er Zi (Xanthium fruit), which has mild toxicity and is traditionally cautioned against in pregnancy, and the overall dispersing, downward-draining nature of the formula.

Avoid

Known allergy or hypersensitivity to any of the formula's ingredients. Cang Er Zi in particular requires proper processing (炒) to reduce its inherent toxicity and should never be used raw.

Caution

Pre-existing Yin deficiency with dryness signs (dry nose, dry throat, scant nasal discharge). The formula's warm, acrid, and drying herbs may further deplete fluids and worsen mucosal dryness.

Caution

Severe liver disease. Cang Er Zi contains hepatotoxic glycosides, and although proper processing significantly reduces toxicity, patients with compromised liver function should use this formula with caution and under professional supervision.

Caution

Prolonged continuous use beyond recommended courses. Cang Er Zi should not be taken continuously for extended periods due to cumulative toxicity concerns. The formula is best suited for course-based treatment with periodic reassessment.

Special Populations

Important considerations for pregnancy, breastfeeding, and pediatric use

Pregnancy

Contraindicated during pregnancy. Cang Er Zi (Xanthium fruit), the formula's primary herb, has documented mild toxicity and is traditionally cautioned against in pregnant women. Additionally, several herbs in the formula have strong dispersing and moving properties that could theoretically affect the fetus. Huang Bai (Phellodendron bark), present in some versions, is cold and bitter and drains downward, which is generally avoided in pregnancy. Women who are pregnant or planning to become pregnant should not use this formula without explicit guidance from a qualified practitioner.

Breastfeeding

Use with caution during breastfeeding. While there is no specific classical prohibition, Cang Er Zi (Xanthium fruit) contains toxic glycosides that could theoretically transfer into breast milk, and its safety profile during lactation has not been formally studied. The formula also contains strongly aromatic and dispersing herbs whose effects on the nursing infant are unknown. If a breastfeeding mother requires treatment for nasal congestion or sinusitis, she should consult a qualified practitioner who can assess whether the benefits outweigh the risks or recommend a safer alternative.

Children

Not generally recommended for young children under age 6 without professional supervision. Cang Er Zi (Xanthium fruit) has mild hepatotoxicity concerns, and children's livers are more susceptible to toxic effects. For children aged 6 and above, some practitioners may prescribe reduced doses (typically one-half to one-third of the adult dose depending on age and body weight), but this should always be guided by a qualified TCM practitioner. The course of treatment in children should be kept short. For pediatric nasal congestion and allergies, gentler formulas or acupuncture may be preferable as first-line approaches.

Drug Interactions

If you are taking pharmaceutical medications, be aware of these potential interactions with Bi Yan Wan

Anticoagulant and antiplatelet medications: Some versions of Bi Yan Wan contain Chuan Xiong (Chuanxiong rhizome) or other Blood-moving herbs. These could theoretically potentiate the effects of warfarin, aspirin, or other anticoagulants, increasing bleeding risk.

Hepatotoxic medications: Because Cang Er Zi (Xanthium fruit) has documented hepatotoxic potential (its toxic glycosides primarily target the liver), concurrent use with other hepatotoxic drugs such as acetaminophen (paracetamol) at high doses, statins, or certain antibiotics may increase the risk of liver injury. Patients taking medications metabolized by the liver should inform their practitioner.

Sedative medications: Wu Wei Zi (Schisandra fruit), present in some formulations, has mild sedative properties and may theoretically enhance the effects of benzodiazepines, barbiturates, or other CNS depressants.

Antihypertensive medications: Gan Cao (Licorice root), if present in the formulation, can cause sodium retention and potassium loss with prolonged use, potentially counteracting antihypertensive drugs and interacting with diuretics or digoxin. However, the amount in patent pill form is generally small.

Usage Guidance

Practical advice for getting the most out of Bi Yan Wan

Best time to take

After meals, 2-3 times daily, with warm water.

Typical duration

Acute use: 1-2 weeks per course. Chronic or recurrent conditions may require 2-4 weeks, with reassessment between courses. Not intended for continuous long-term use.

Dietary advice

Avoid greasy, fried, and rich foods while taking this formula, as these generate Dampness and Phlegm that worsen nasal congestion. Dairy products and cold or raw foods (ice cream, cold drinks, raw salads) should be minimized, as they can increase mucus production from a TCM perspective. Spicy-hot foods like chili peppers should also be moderated if there are pronounced Heat signs (yellow nasal discharge, red eyes). Light, warm, easily digestible meals are best. Drinking adequate warm water supports the formula's dispersing action. Pungent, aromatic foods like ginger tea, scallions, and cilantro can gently complement the formula's ability to open the nasal passages.

Bi Yan Wan originates from Modern formula derived from Cāng Ěr Zǐ Sǎn (苍耳子散) of Jì Shēng Fāng (济生方) by Yán Yòng-Hé (严用和) Modern formulation (based on Sòng dynasty source, 1253 CE)

Classical Texts

Key passages from the classical Chinese medical texts that first described Bi Yan Wan and its clinical use

Bi Yan Wan (鼻炎丸/鼻炎片) is a modern patent medicine formulation rather than a classical decoction from a single ancient text. However, its core design draws heavily from Cang Er Zi San (苍耳子散), which originates from the Song dynasty text Ji Sheng Fang (《济生方》, Formulas to Aid the Living) by Yan Yong-He (严用和), written in 1253 CE. The classical quotes below relate to this foundational source formula and the herbs central to Bi Yan Wan's mechanism.

The Ji Sheng Fang records the original Cang Er Zi San indication as: 「治鼻流浊涕不止:辛夷半两,苍耳子二钱半,香白芷一两,薄荷叶半钱。上并晒干,为细末。每服二钱,用葱、茶清食后调服。」 ("For continuous flow of turbid nasal discharge: Xin Yi [Magnolia flower] half liang, Cang Er Zi [Xanthium fruit] two and a half qian, fragrant Bai Zhi one liang, Bo He [Mint] leaf half qian. Dry all together and grind to fine powder. Take two qian per dose, adjusted with scallion and tea infusion after meals.")

The Yi Fang Ji Jie (《医方集解》) commentary explains: 「凡头面之疾,皆由清阳不升,浊阴逆上所致」 ("All diseases of the head and face arise from the failure of clear Yang to ascend, and the perverse upward movement of turbid Yin.") This captures the core pathological principle that Bi Yan Wan addresses.

Regarding the chief herb Cang Er Zi, the Ben Cao Zheng Yi (《本草正义》) states that it 「独能上达巅顶,疏通脑户之风寒」 ("uniquely reaches the crown of the head and disperses Wind-Cold from the passages of the brain"), explaining its special affinity for nasal and sinus conditions.

Historical Context

How Bi Yan Wan evolved over the centuries — its origins, lineage, and place in the broader tradition of Chinese medicine

Bi Yan Wan (鼻炎丸) and its tablet form Bi Yan Pian (鼻炎片) are modern Chinese patent medicines rather than classical formulas from a single ancient text. They were developed in the 20th century as standardized over-the-counter remedies for rhinitis and sinusitis, drawing on classical formula principles. The formula's design represents a synthesis of two key classical strategies: Cang Er Zi San (苍耳子散) from Yan Yong-He's Ji Sheng Fang (1253 CE) for opening the nasal passages, and additional Heat-clearing and Wind-dispersing herbs to broaden its scope to Wind-Heat patterns.

The ancestral formula Cang Er Zi San is elegantly simple, containing just four herbs (Cang Er Zi, Xin Yi, Bai Zhi, and Bo He). It became the foundational prescription for nasal conditions throughout Chinese medical history and has appeared under various names including "Zhi Yi San" and "Zhi Xin San." Modern Bi Yan Wan significantly expanded this base by adding Heat-clearing herbs like Lian Qiao (Forsythia), Huang Bai (Phellodendron), and Ye Ju Hua (Wild Chrysanthemum), along with Wind-expelling herbs like Jing Jie (Schizonepeta) and Fang Feng (Saposhnikovia), and the Lung Qi-consolidating Wu Wei Zi (Schisandra). This expansion transformed a simple Wind-Cold-focused nasal remedy into a broader-spectrum formula capable of addressing both Wind-Heat and Wind-Cold with Heat transformation patterns.

Bi Yan Pian became one of the most widely exported Chinese patent medicines globally from the 1980s onward, particularly popular in Western countries for seasonal allergies and sinus infections. It is one of the few TCM patent medicines that many Western acupuncturists and herbalists commonly recommend to patients.