Shi Pi Yin

Bolster the Spleen Decoction · 實脾飲

Also known as: Shi Pi San (實脾散), Bolster the Spleen Powder

A classical warming formula used to treat chronic swelling and fluid retention (edema), especially in the lower body, caused by weakness and coldness of the digestive and kidney systems. It warms the body's core, strengthens digestion, and helps the body eliminate excess fluid. Typical signs include puffy legs and ankles, cold hands and feet, bloating, fatigue, and loose stools.

Origin Ji Sheng Fang (嚴氏濟生方, Yan's Formulas for Saving Lives) by Yan Yonghe (嚴用和) — Southern Sòng dynasty, 1253 CE
Composition 12 herbs
Zhi Fu Zi
King
Zhi Fu Zi
Gan Jiang
King
Gan Jiang
Fu Ling
Deputy
Fu Ling
Bai Zhu
Deputy
Bai Zhu
Mu Gua
Assistant
Mu Gua
Hou Pu
Assistant
Hou Pu
Mu Xiang
Assistant
Mu Xiang
Da Fu Pi
Assistant
Da Fu Pi
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Educational content Consult qualified TCM practitioners for diagnosis and treatment

Patterns Addressed

In TCM, symptoms don't appear randomly — they cluster into recognizable patterns of disharmony that reveal what's out of balance in the body. Shi Pi Yin is designed to correct these specific patterns.

Why Shi Pi Yin addresses this pattern

This is the primary pattern Shi Pi Yin addresses. When both the Spleen and Kidney Yang are deficient, the body loses its ability to transform and move fluids. The Kidney's fire (the Gate of Vitality) fails to warm and vaporize water, while the Spleen can no longer transport fluids upward and outward. Water accumulates internally, spilling into the tissues as edema. Because water is a Yin pathogen that naturally sinks downward, the swelling is worst in the lower body. The formula uses Fu Zi and Gan Jiang to restore the warming fire of Kidney and Spleen, while Fu Ling, Bai Zhu, and the Qi-moving herbs re-establish the pathways for fluid circulation and elimination.

A practitioner would look for one or more of these signs

Edema

Especially from the waist down

Cold Extremities

Hands and feet not warm

Abdominal Distention

Chest and abdominal fullness and bloating

Loose Stools

Soft or watery stools

Decreased Urination

Scanty urination

Poor Appetite

Reduced food intake, body feels heavy

Eye Fatigue

Body heaviness and tiredness

Absence Of Thirst

No desire to drink, or preference for warm drinks

Commonly Prescribed For

These conditions can arise from the patterns above. A practitioner would consider Shi Pi Yin when these conditions are specifically caused by those patterns — not for all cases of these conditions.

TCM Interpretation

In TCM, edema arises when the body's water metabolism breaks down. Three organ systems govern water: the Lungs spread and descend fluids, the Spleen transforms and transports them, and the Kidneys provide the warming fire (Yang) to vaporize and excrete them. When Spleen and Kidney Yang are both weak, fluids cannot be properly transformed or moved. They accumulate and overflow into the tissues, causing swelling. Because water is heavy and sinks, Yin-type edema characteristically affects the lower half of the body, the legs, ankles, and abdomen. Unlike acute edema from external causes (which often starts at the face and upper body), this chronic form reflects deep internal weakness.

Why Shi Pi Yin Helps

Shi Pi Yin directly targets the two root causes of Yin edema: deficient Kidney Yang (addressed by Fu Zi) and deficient Spleen Yang (addressed by Gan Jiang). By restoring warmth to these two organ systems, the formula re-activates the body's fluid transformation pathways. Fu Ling and Bai Zhu then strengthen the Spleen and provide direct drainage of excess dampness through urination. The Qi-moving herbs (Hou Po, Mu Xiang, Da Fu Pi, Cao Guo) ensure that stagnant fluids in the abdomen are mobilized and expelled. This multi-layered approach, warming the root while draining the branch, makes it the classical representative formula for chronic Yang-deficient edema.

Also commonly used for

Chronic Glomerulonephritis

Chronic kidney inflammation with edema and Yang deficiency pattern

Nephrotic Syndrome

With significant edema and Yang deficiency presentation

Chronic Bronchitis

With edema and fluid retention in the elderly

Hypothyroidism

Myxedema with cold signs and fluid retention

What This Formula Does

Every TCM formula has a specific set of actions — here's what Shi Pi Yin does in the body, explained in both everyday and TCM terms

Therapeutic focus

In practical terms, Shi Pi Yin is primarily used to support these areas of health:

TCM Actions

In TCM terminology, these are the specific therapeutic actions that Shi Pi Yin performs to restore balance in the body:

How It Addresses the Root Cause

TCM doesn't just suppress symptoms — it aims to resolve the underlying imbalance. Here's how Shi Pi Yin works at the root level.

Shi Pi Yin addresses a condition known in TCM as yin-type edema (阴水, yīn shuǐ), which arises from a fundamental weakness of warming power in both the Spleen and Kidneys.

In TCM theory, the Spleen is responsible for transforming and transporting fluids throughout the body. When Spleen Yang is weak, this fluid-processing function breaks down, and water begins to accumulate rather than being properly distributed or excreted. At the same time, the Kidneys serve as the body's "gate of water" (水之关门), governing the opening and closing of the waterways in the lower body. When Kidney Yang (sometimes called "Ming Men fire" or the fire of the Gate of Vitality) is also insufficient, it can no longer warm the Spleen from below or drive urination, so fluid pools in the lower half of the body. This is why yin-type edema characteristically appears as swelling that is worst from the waist down. The limbs become cold because Yang cannot warm the extremities. Stools become loose because the Spleen cannot absorb fluids properly. The person is not thirsty because there is no Heat consuming fluids. The tongue coating turns white and greasy because Cold Dampness is accumulating internally, and the pulse sinks deep and slow, reflecting the Yang deficiency and fluid obstruction within.

Adding to this, when Qi fails to move properly due to Yang deficiency, Dampness congeals and Qi stagnates, producing a feeling of fullness and distension in the chest and abdomen. The condition is thus a vicious cycle: weak Yang leads to fluid retention, and accumulated fluid further obstructs Qi circulation, which in turn worsens the Yang deficiency. The formula's strategy of simultaneously warming Yang, strengthening the Spleen, moving Qi, and draining water addresses all facets of this interlocking pathology.

Formula Properties

Every formula has an inherent temperature, taste, and affinity for specific organs — these properties determine how it interacts with the body

Overall Temperature

Warm

Taste Profile

Predominantly acrid (pungent) and bitter with a sweet undertone. The acrid flavor disperses and warms to move Qi and transform Dampness, the bitter flavor dries Dampness and directs downward, and the sweet flavor tonifies the Spleen.

Channels Entered

Ingredients

12 herbs

The herbs that make up Shi Pi Yin, organized by their role in the prescription

King — Main ingredient driving the formula
Deputy — Assists and enhances the King
Assistant — Supports or moderates other herbs
Envoy — Directs the formula to its target
Kings — Main ingredient driving the formula
Zhi Fu Zi

Zhi Fu Zi

Prepared aconite

Dosage 3 - 9g
Temperature Hot
Taste Pungent, Sweet
Organ Affinity Heart, Kidneys, Spleen
Preparation Use prepared (炮) form; decoct first for 30-60 minutes to reduce toxicity

Role in Shi Pi Yin

Warms Kidney Yang and restores the fire of the Gate of Vitality, powerfully assisting Qi transformation to move water. As the primary warming agent for the Kidneys, it addresses the root Yang deficiency that allows water to accumulate.
Gan Jiang

Gan Jiang

Dried ginger

Dosage 3 - 6g
Temperature Hot
Taste Pungent
Organ Affinity Heart, Kidneys, Lungs, Stomach

Role in Shi Pi Yin

Warms the Spleen Yang and restores its transforming and transporting functions. Works alongside Fu Zi to warm both Spleen and Kidney, suppressing Yin excess and driving out cold-dampness from the Middle Burner.
Deputies — Assists and enhances the King
Fu Ling

Fu Ling

Poria-cocos mushrooms

Dosage 9 - 15g
Temperature Neutral
Taste Sweet
Organ Affinity Heart, Kidneys, Lungs, Spleen

Role in Shi Pi Yin

Strengthens the Spleen and leaches out dampness through urination. By promoting the downward passage of water through the Bladder, it directly reduces edema while supporting the Spleen's ability to manage fluids.
Bai Zhu

Bai Zhu

Atractylodes rhizomes

Dosage 6 - 12g
Temperature Warm
Taste Bitter, Sweet
Organ Affinity Spleen, Stomach

Role in Shi Pi Yin

Tonifies Spleen Qi and dries dampness, reinforcing the Spleen's capacity to transform and transport fluids. Pairs with Fu Ling to strengthen the Spleen from both the tonifying and draining sides.
Assistants — Supports or moderates other herbs
Mu Gua

Mu Gua

Flowering quince

Dosage 6 - 9g
Temperature Warm
Taste Sour
Organ Affinity Liver, Spleen

Role in Shi Pi Yin

Resolves dampness, relaxes the sinews, and harmonizes the Stomach. Its sour-warm nature gently restrains Liver Wood from overacting on weakened Spleen Earth, while also helping transform dampness in the Middle Burner.
Hou Pu

Hou Pu

Houpu Magnolia bark

Dosage 3 - 6g
Temperature Warm
Taste Bitter, Pungent
Organ Affinity Lungs, Spleen, Stomach

Role in Shi Pi Yin

Moves Qi, transforms dampness, and relieves abdominal distention and fullness. Its bitter-warm drying nature helps break through the stagnant dampness that blocks the Middle Burner's Qi flow.
Mu Xiang

Mu Xiang

Costus roots

Dosage 3 - 6g
Temperature Warm
Taste Bitter, Pungent
Organ Affinity Gallbladder, Large Intestine, Liver, Lungs, Spleen, Stomach

Role in Shi Pi Yin

Promotes the smooth flow of Qi in the Spleen and Stomach, counteracting the bloating and fullness caused by water stagnation. Ensures that the warming and draining actions of the formula are carried through by healthy Qi movement.
Da Fu Pi

Da Fu Pi

Areca peel

Dosage 6 - 9g
Temperature Warm
Taste Pungent
Organ Affinity Spleen, Stomach, Large Intestine, Small Intestine

Role in Shi Pi Yin

Moves Qi downward, breaks through stagnation, and promotes urination to drain water. Its descending action helps relieve the abdominal distension and edema of the lower body.
Cao Guo

Cao Guo

Tsaoko fruits

Dosage 3 - 6g
Temperature Warm
Taste Pungent
Organ Affinity Spleen, Stomach

Role in Shi Pi Yin

Dries dampness and warms the Middle Burner, dissolving turbid dampness that obstructs the Spleen's function. Its aromatic, drying nature cuts through the heavy, cold-damp accumulation characteristic of Yin edema.
Envoys — Directs the formula to its target
Gan Cao

Gan Cao

Liquorice

Dosage 3 - 6g
Temperature Neutral
Taste Sweet
Organ Affinity Heart, Lungs, Spleen, Stomach

Role in Shi Pi Yin

Tonifies the Spleen and harmonizes all the other herbs in the formula. Its sweet, warming nature supports the Middle Burner and moderates the strong actions of the other ingredients.
Sheng Jiang

Sheng Jiang

Fresh ginger

Dosage 3 - 5 slices
Temperature Warm
Taste Pungent
Organ Affinity Lungs, Spleen, Stomach

Role in Shi Pi Yin

Warms the Stomach, assists the Middle Burner, and helps scatter water-dampness. Serves as an adjunct to Gan Jiang's warming action while also harmonizing the Stomach to prevent nausea from the heavy herbs in the formula.
Da Zao

Da Zao

Jujube dates

Dosage 3 - 5 pieces
Temperature Warm
Taste Sweet
Organ Affinity Spleen, Stomach

Role in Shi Pi Yin

Tonifies the Spleen and Stomach and harmonizes the formula. Together with Sheng Jiang and Zhi Gan Cao, it protects the middle and buffers the strong warming and moving herbs.

Why This Combination Works

How the herbs in Shi Pi Yin complement each other

Overall strategy

Shi Pi Yin addresses Yin-type edema caused by Spleen and Kidney Yang deficiency with internal water-dampness accumulation. The formula warms the Yang of both Spleen and Kidney to restore their ability to transform fluids, while simultaneously moving Qi and draining water to clear the accumulated dampness.

King herbs

Fu Zi (prepared Aconite) and Gan Jiang (dried Ginger) serve as the dual King herbs, targeting the root cause: Yang deficiency of both Kidney and Spleen. Fu Zi excels at warming Kidney Yang to restore the Qi transformation needed for water metabolism, while Gan Jiang focuses on warming Spleen Yang to restore its transporting function. Together they suppress Yin excess and restore the fire that keeps fluids moving.

Deputy herbs

Fu Ling (Poria) and Bai Zhu (White Atractylodes) reinforce the King herbs by directly strengthening the Spleen and draining dampness. Bai Zhu tonifies and dries from the inside, while Fu Ling leaches dampness downward through urination. This pairing ensures the Spleen has the functional capacity to handle fluids once Yang is restored.

Assistant herbs

Four herbs move Qi and transform dampness: Hou Po, Mu Xiang, Da Fu Zi (Areca), and Cao Guo work together to break through Qi stagnation and clear turbid dampness from the abdomen. This is a key design feature, because when Qi flows freely, dampness transforms naturally and distension resolves. Mu Gua serves a restraining role, using its sour-warm nature to calm the Liver and prevent Wood from overacting on the already-weakened Spleen. As the classical commentator Wang Ang noted, Mu Gua and Mu Xiang together pacify the Liver so that it does not attack the Spleen.

Envoy herbs

Zhi Gan Cao, Sheng Jiang, and Da Zao form the harmonizing trio. Gan Cao tonifies the Middle Burner and moderates the formula's strong warming and moving herbs. Sheng Jiang assists in scattering water-dampness and warming the Stomach, while Da Zao nourishes the Spleen. Together they protect the digestive system and ensure smooth interaction among the other ingredients.

Notable synergies

The Fu Zi and Gan Jiang pairing is a classical combination that warms both above and below, restoring Yang throughout the Spleen-Kidney axis. The four Qi-moving assistants (Hou Po, Mu Xiang, Da Fu Zi, Cao Guo) work as a coordinated group rather than individually, ensuring that dampness is attacked from multiple angles: aromatic transformation, downward drainage, and Qi circulation. The inclusion of Mu Gua alongside Mu Xiang represents the formula's attention to the Wood-Earth relationship, preventing the Liver from compounding the Spleen's weakness.

How to Prepare

Traditional preparation instructions for Shi Pi Yin

Originally prepared as a powder (散剂): the herbs were coarsely ground, and approximately 12g was taken per dose, decocted in one and a half cups of water with 5 slices of fresh ginger and 1 jujube date, simmered until about 70% of the liquid remained, then strained and taken warm at any time of day.

Modern usage: decoct all ingredients together in water as a standard decoction (汤剂). Use dosages in proportion to the original formula. The prepared Aconite (Zhi Fu Zi) should be decocted first for 30 to 60 minutes before adding the remaining herbs to reduce its toxicity. Decoct the full formula for approximately 30 minutes. Take warm, typically twice daily.

Common Modifications

How practitioners adapt Shi Pi Yin for specific situations

Added
Huang Qi

15-30g, to strongly tonify Qi and assist water metabolism

Dang Shen

9-15g, to supplement Spleen Qi

When Qi deficiency is prominent, Huang Qi and Dang Shen boost the Spleen's vital force. Huang Qi also has a direct effect on promoting urination and reducing edema by lifting Qi.

Educational content — always consult a qualified healthcare provider or TCM practitioner before using any herbal formula.

Contraindications

Situations where Shi Pi Yin should not be used or requires extra caution

Avoid

Yang-type edema (yang shui) with signs of Heat such as red face, thirst with desire for cold drinks, dark scanty urine, rapid pulse, or yellow tongue coating. This formula is specifically designed for Cold-type (yin) edema and will worsen Heat conditions.

Avoid

Edema due to Yin deficiency with Empty Heat. The warm and drying nature of this formula (Fu Zi, Gan Jiang, Cao Guo) will further damage Yin fluids.

Avoid

Pregnancy. The formula contains Fu Zi (prepared Aconite), which is toxic and can stimulate uterine contractions, and several strongly Qi-moving herbs (Da Fu Pi, Mu Xiang, Hou Po) that may disturb fetal Qi.

Caution

Patients with true Heat and false Cold presentations. Careful differentiation is needed to avoid mistaking this pattern for Spleen-Kidney Yang deficiency.

Caution

Patients with significant Qi or Blood deficiency without pronounced Yang deficiency. The formula's strong warming and draining action may deplete already weakened resources. Consider adding tonifying herbs if needed.

Caution

Patients taking cardiac glycosides (e.g. digoxin) or anti-arrhythmic medications, due to the aconitine alkaloids in Fu Zi which can affect cardiac rhythm.

Special Populations

Important considerations for pregnancy, breastfeeding, and pediatric use

Pregnancy

Contraindicated during pregnancy. The formula contains Fu Zi (prepared Aconite root), which contains aconitine alkaloids and is classified as a toxic substance that may adversely affect fetal development and can stimulate uterine contractions. Additionally, several ingredients in the formula are strongly Qi-moving (Da Fu Pi, Mu Xiang, Hou Po, Cao Guo), which carry a risk of disturbing fetal Qi and potentially promoting miscarriage. Pregnant women with edema should be treated with safer alternatives under professional guidance.

Breastfeeding

Use with caution during breastfeeding. Fu Zi (prepared Aconite) contains aconitine alkaloids that could potentially transfer into breast milk. While the formula uses the processed (pao) form of Fu Zi, which has significantly reduced toxicity, the potential risk to the nursing infant has not been formally studied. If the formula is clinically necessary for the breastfeeding mother, it should be prescribed under close professional supervision, using the minimum effective dose, and the infant should be monitored for any signs of irritability, feeding changes, or unusual symptoms. Gan Jiang (dried Ginger) and other warming herbs are generally considered low risk during lactation.

Children

Shi Pi Yin may be used in children under close professional supervision, but significant dosage adjustments are necessary. Pediatric dosing should typically be reduced to one-third to one-half of the adult dose depending on age and body weight. The presence of Fu Zi (prepared Aconite) demands particular caution in children, as they are more sensitive to aconitine alkaloids. Fu Zi must always be thoroughly pre-decocted (at least 30-60 minutes) before adding other herbs, and the dose should be kept at the lower end. Children under 3 years of age should generally not be given this formula. For children ages 3-12, start at approximately one-third the adult dose. Monitor closely for any signs of numbness of the tongue or lips, nausea, or palpitations, which may indicate aconite sensitivity.

Drug Interactions

If you are taking pharmaceutical medications, be aware of these potential interactions with Shi Pi Yin

Fu Zi (prepared Aconite root) contains aconitine alkaloids that have significant cardiac effects. It should be used with extreme caution alongside:

  • Cardiac glycosides (e.g. digoxin): Both Fu Zi and digoxin affect cardiac rhythm, and concurrent use may increase the risk of dangerous arrhythmias.
  • Anti-arrhythmic medications: Aconitine has its own effects on cardiac sodium and potassium channels, potentially creating unpredictable interactions with drugs like amiodarone, flecainide, or beta-blockers.

Gan Cao (Licorice root) contains glycyrrhizin, which can cause potassium depletion and sodium retention with prolonged use. It may interact with:

  • Diuretics (e.g. furosemide, hydrochlorothiazide): May compound potassium loss, increasing the risk of hypokalemia.
  • Corticosteroids: Glycyrrhizin can potentiate the effects of corticosteroids by inhibiting their metabolism.
  • Antihypertensive medications: Licorice-induced sodium retention can counteract blood pressure-lowering effects.
  • Digoxin: Hypokalemia from Gan Cao can increase sensitivity to digoxin toxicity.

Da Fu Pi (Areca peel) has cholinergic-like properties and should be used cautiously alongside cholinesterase inhibitors or anticholinergic medications.

Patients taking any cardiovascular, diuretic, or corticosteroid medications should inform their prescribing physician before using this formula.

Usage Guidance

Practical advice for getting the most out of Shi Pi Yin

Best time to take

Warm, 30 minutes before meals, twice daily (morning and afternoon). The classical text specifies taking it warm without time restriction (温服,不拘时服).

Typical duration

Typically prescribed for 1-4 weeks for acute edema episodes, with reassessment by the practitioner. Chronic conditions may require longer courses of 4-8 weeks with regular monitoring and formula adjustments.

Dietary advice

Avoid cold and raw foods (salads, iced drinks, raw fruits in excess, ice cream) while taking this formula, as these directly counteract its warming action and further burden the Spleen Yang. Also avoid greasy, oily, and heavy foods that generate Dampness and obstruct Qi movement. Limit salt intake, as excess salt promotes water retention and worsens edema. Favor warm, easily digestible, cooked foods such as congee (rice porridge), soups with ginger, cooked root vegetables, and small amounts of warming spices like ginger and cinnamon in cooking. Moderate protein intake is helpful, but avoid excessive dairy products which tend to generate Dampness.

Shi Pi Yin originates from Ji Sheng Fang (嚴氏濟生方, Yan's Formulas for Saving Lives) by Yan Yonghe (嚴用和) Southern Sòng dynasty, 1253 CE

Classical Texts

Key passages from the classical Chinese medical texts that first described Shi Pi Yin and its clinical use

From the Chóng Dìng Yán Shì Jì Shēng Fāng (重订严氏济生方), Water Edema Chapter (水肿门):

「阴水为病,脉来沉迟,色多青白,不烦不渴,小便涩少而清,大腑多泄,此阴水也,则宜用温暖之剂,如实脾散、复元丹是也。」

Translation: "When yin-type edema is the disease, the pulse arrives deep and slow, the complexion tends toward pale or bluish-white, there is no irritability or thirst, urination is scanty yet clear, and the bowels tend toward loose stools. This is yin-type edema, and warming formulas should be used, such as Shi Pi San and Fu Yuan Dan."

This passage establishes the core diagnostic framework for the formula: it treats the Cold, deficiency type of edema (yin shui) as opposed to the Hot, excess type (yang shui). The key signs are all indicators of Yang deficiency and internal Cold with water accumulation.

Classical treatment principle from the same text:

「治阴水,先实脾土。」

Translation: "To treat yin-type edema, first bolster the Spleen Earth." This concise principle gives the formula its name and encapsulates its therapeutic strategy: strengthening and warming the Spleen is the foundation for resolving Cold-type water retention.

Historical Context

How Shi Pi Yin evolved over the centuries — its origins, lineage, and place in the broader tradition of Chinese medicine

Shi Pi Yin (实脾饮, also known as Shi Pi San 实脾散) was created by the Southern Song Dynasty physician Yan Yonghe (严用和, c. 1199–1267), courtesy name Zili (子礼). It was recorded in his major work, the Jì Shēng Fāng (济生方, Formulas to Aid the Living), completed in 1253 CE. Yan Yonghe was a native of Lushan in Jiangxi province who began studying medicine at age 12 under the renowned physician Liu Kai, and started practicing at 17. He accumulated over 50 years of clinical experience.

The formula's name literally means "Bolster the Spleen Decoction," directly reflecting Yan's treatment principle: "To treat yin-type edema, first bolster the Spleen Earth" (治阴水,先实脾土). This was a significant contribution to the theory of edema management, clearly distinguishing between yang-type edema (requiring cooling and draining) and yin-type edema (requiring warming and tonifying). Yan Yonghe's approach exemplified the Song Dynasty trend of refining clinical differentiation and creating targeted formulas rather than relying on generic ancient prescriptions.

The Ji Sheng Fang was widely praised. The Yuan Dynasty scholar Wu Cheng (吴澄) commended its prescriptions as "neither excessive nor superfluous, and effective when used" (不泛不繁,用之辄有功). Unfortunately, the original text was lost over time. It was later reconstructed from the Yongle Dadian encyclopedia and other sources, eventually published as the Chongding Yan Shi Ji Sheng Fang (重订严氏济生方). Yan Yonghe is also credited with other famous formulas including Gui Pi Tang (Restore the Spleen Decoction), Xiao Ji Yin Zi (Small Thistle Drink), and Ji Sheng Shen Qi Wan (his modified Kidney Qi Pill with added Niu Xi and Che Qian Zi).