Ren Shen Lu Rong Tang

Ginseng and Deer Antler Velvet Decoction · 人參鹿茸湯

Also known as: Ren Shen Lu Rong Wan (人参鹿茸丸), Shen Rong Tang

A powerful warming and tonifying formula designed to replenish Kidney essence, boost Qi, and nourish Blood. It is used for people experiencing deep exhaustion, weak lower back and knees, feeling cold easily, poor hearing and vision, and general decline in vitality due to long-term Kidney deficiency with Qi and Blood weakness.

Origin Derived from the Cān Róng Wèi Shēng Wán (参茸卫生丸) tradition; standardized by Tóng Rén Táng (同仁堂) as a classical patent medicine formula — Qīng dynasty, traditional patent medicine formulation
Composition 15 herbs
Ren Shen
King
Ren Shen
Lu Rong
King
Lu Rong
Huang Qi
Deputy
Huang Qi
Dang Gui
Deputy
Dang Gui
Ba Ji Tian
Assistant
Ba Ji Tian
Bu Gu Zhi
Assistant
Bu Gu Zhi
Tu Si Zi
Assistant
Tu Si Zi
Du Zhong
Assistant
Du Zhong
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Educational content Consult qualified TCM practitioners for diagnosis and treatment

Patterns Addressed

In TCM, symptoms don't appear randomly — they cluster into recognizable patterns of disharmony that reveal what's out of balance in the body. Ren Shen Lu Rong Tang is designed to correct these specific patterns.

Why Ren Shen Lu Rong Tang addresses this pattern

Kidney Yang deficiency is the primary pattern addressed by this formula. When Kidney Yang declines, the body's foundational warming capacity fails, leading to cold extremities, weak lower back and knees, frequent urination, and reduced sexual vitality. Lu Rong, Ba Ji Tian, Bu Gu Zhi, and Du Zhong directly warm Kidney Yang and replenish the Ming Men fire. Dong Chong Xia Cao further supports Kidney Yang while protecting Yin. Ren Shen and Huang Qi ensure the Spleen generates enough Qi to support the Kidney restoration, while Wu Wei Zi prevents essence leakage.

A practitioner would look for one or more of these signs

Cold Extremities

Persistent cold hands and feet from deficient Yang failing to warm the limbs

Lower Back Pain

Dull, chronic aching in the lower back that improves with warmth and rest

Cold Knees

Cold and weak knees, difficulty standing for long periods

Frequent Urination

Frequent, clear, copious urination, especially at night

Erectile Dysfunction

Impotence or reduced sexual function from declining Ming Men fire

Tinnitus

Tinnitus or declining hearing from Kidney essence failing to nourish the ears

Commonly Prescribed For

These conditions can arise from the patterns above. A practitioner would consider Ren Shen Lu Rong Tang when these conditions are specifically caused by those patterns — not for all cases of these conditions.

TCM Interpretation

In TCM, chronic fatigue that does not resolve with rest reflects a deep depletion of the body's foundational resources. The Kidneys store the body's constitutional essence and provide the warming fire (Ming Men) that drives all organ functions. When Kidney Yang declines, the Spleen loses its source of warming support and cannot efficiently produce Qi and Blood from food. This creates a vicious cycle: weak Kidneys weaken the Spleen, and a weak Spleen cannot generate enough Qi and Blood to replenish the Kidneys. The result is profound tiredness, cold body, weak limbs, poor appetite, and mental fog.

Why Ren Shen Lu Rong Tang Helps

Ren Shen Lu Rong Tang breaks this vicious cycle by working on both ends simultaneously. Lu Rong and its supporting herbs (Ba Ji Tian, Bu Gu Zhi, Du Zhong) rekindle the Kidney's warming fire, restoring the foundational drive. Ren Shen and Huang Qi directly replenish Qi and strengthen the Spleen's ability to produce more. Dang Gui and Long Yan Rou nourish Blood so that restored Qi has a vehicle for circulation. Dong Chong Xia Cao uniquely bridges both the Kidney and Lung, supporting both the deep reserves and the daily Qi production. Fu Ling ensures digestion stays functional despite the heavy tonics.

Also commonly used for

Tinnitus

Ringing in the ears from Kidney essence insufficiency

Hearing Loss

Progressive hearing decline in aging

Blurry Vision

Dim vision associated with Kidney-Liver deficiency

Frequent Urination

Nocturia and frequent clear urination

Infertility

Male or female infertility from essence deficiency

Poor Memory

Declining memory and concentration in aging

Osteoporosis

Bone weakness and fragility from Kidney essence decline

Anemia

Anemia with concurrent Kidney Yang deficiency signs

What This Formula Does

Every TCM formula has a specific set of actions — here's what Ren Shen Lu Rong Tang does in the body, explained in both everyday and TCM terms

Therapeutic focus

In practical terms, Ren Shen Lu Rong Tang is primarily used to support these areas of health:

TCM Actions

In TCM terminology, these are the specific therapeutic actions that Ren Shen Lu Rong Tang performs to restore balance in the body:

How It Addresses the Root Cause

TCM doesn't just suppress symptoms — it aims to resolve the underlying imbalance. Here's how Ren Shen Lu Rong Tang works at the root level.

This formula addresses a pattern of deep, dual deficiency involving both Kidney Yang depletion and Qi-Blood insufficiency. In TCM theory, the Kidneys store Essence (Jing), which is the constitutional root of all the body's vitality. When Kidney Essence and Kidney Yang become depleted through chronic illness, aging, overwork, or excessive sexual activity, the body loses its foundational warming and animating force. Without adequate Kidney Yang (sometimes called Ming Men Fire, the "Gate of Vitality"), the body cannot warm the limbs, support the lower back and knees, maintain reproductive function, or generate sufficient Qi and Blood.

Because the Kidneys are the root of both Yin and Yang for the entire body, when Kidney Yang is weak, it fails to warm the Spleen, which in turn cannot properly transform food into Qi and Blood. This creates a downward spiral: weak Kidneys undermine the Spleen, inadequate Qi and Blood production further starves the Kidneys of nourishment, and the whole system becomes progressively depleted. The result is a constellation of signs like fatigue, cold limbs, sore lower back and knees, poor hearing and vision, frequent urination, weak digestion, pale complexion, and diminished libido or fertility.

Ren Shen Lu Rong Tang intervenes at both ends of this cycle. It directly replenishes Kidney Essence and restores Kidney Yang (the root problem), while simultaneously boosting Qi and Blood production (the secondary consequences). This dual approach addresses the underlying mechanism rather than just the symptoms, making it suited for chronic, deep-seated deficiency rather than acute conditions.

Formula Properties

Every formula has an inherent temperature, taste, and affinity for specific organs — these properties determine how it interacts with the body

Overall Temperature

Warm

Taste Profile

Predominantly sweet and slightly salty, with mild bitterness. Sweet to tonify Qi and Blood, salty to enter the Kidneys and supplement Essence, with the warmth of Yang-tonifying herbs underlying the whole formula.

Channels Entered

Ingredients

15 herbs

The herbs that make up Ren Shen Lu Rong Tang, organized by their role in the prescription

King — Main ingredient driving the formula
Deputy — Assists and enhances the King
Assistant — Supports or moderates other herbs
Envoy — Directs the formula to its target
Kings — Main ingredient driving the formula
Ren Shen

Ren Shen

Ginseng

Dosage 6 - 10g
Temperature Warm
Taste Bitter, Sweet
Organ Affinity Heart, Lungs, Spleen

Role in Ren Shen Lu Rong Tang

Powerfully tonifies the original Qi, strengthens the Spleen and Lungs, generates fluids, and calms the spirit. As one of the two principal herbs, it addresses the core Qi deficiency that underlies the pattern.
Lu Rong

Lu Rong

Pilose antlers

Dosage 1 - 3g
Temperature Warm
Taste Salty, Sweet
Organ Affinity Kidneys, Liver
Preparation Ground to fine powder and dissolved into the strained decoction (冲服)

Role in Ren Shen Lu Rong Tang

Warms and tonifies Kidney Yang, replenishes essence (Jing), strengthens sinews and bones, and nourishes Blood. As the other principal herb, it directly addresses Kidney Yang and essence deficiency.
Deputies — Assists and enhances the King
Huang Qi

Huang Qi

Milkvetch roots

Dosage 9 - 15g
Temperature Warm
Taste Sweet
Organ Affinity Lungs, Spleen

Role in Ren Shen Lu Rong Tang

Reinforces Ren Shen in tonifying Qi, raises Yang, consolidates the exterior, and promotes the generation of Blood. Honey-processed to enhance its Spleen-tonifying function.
Dang Gui

Dang Gui

Dong quai

Dosage 6 - 10g
Temperature Warm
Taste Pungent, Sweet
Organ Affinity Heart, Liver, Spleen

Role in Ren Shen Lu Rong Tang

Tonifies and invigorates Blood, ensuring that the Qi-tonifying herbs have adequate Blood to support. Works synergistically with Ren Shen and Huang Qi to address the concurrent Blood deficiency.
Assistants — Supports or moderates other herbs
Ba Ji Tian

Ba Ji Tian

Morinda roots

Dosage 6 - 10g
Temperature Warm
Taste Pungent, Sweet
Organ Affinity Kidneys, Liver

Role in Ren Shen Lu Rong Tang

Strengthens Kidney Yang, fortifies sinews and bones, and expels Wind-Dampness. Reinforces Lu Rong in warming the Kidneys and strengthening the lower back and knees.
Bu Gu Zhi

Bu Gu Zhi

Psoralea fruits

Dosage 6 - 10g
Temperature Warm
Taste Bitter, Pungent
Organ Affinity Spleen, Kidneys

Role in Ren Shen Lu Rong Tang

Warms Kidney Yang, secures essence, and warms the Spleen to help hold Qi. Supports the formula's core strategy of restoring Kidney Fire and Ming Men warmth.
Tu Si Zi

Tu Si Zi

Cuscuta seeds

Dosage 6 - 10g
Temperature Warm
Taste Sweet
Organ Affinity Kidneys, Liver, Spleen

Role in Ren Shen Lu Rong Tang

Tonifies both Kidney Yin and Yang in a balanced manner, secures essence, and benefits the eyes. Its gentle, balanced nature helps prevent the warming herbs from becoming too drying.
Du Zhong

Du Zhong

Eucommia bark

Dosage 6 - 10g
Temperature Warm
Taste Sweet
Organ Affinity Kidneys, Liver

Role in Ren Shen Lu Rong Tang

Tonifies the Liver and Kidneys, strengthens sinews and bones, specifically targeting lower back and knee weakness.
Niu Xi

Niu Xi

Achyranthes roots

Dosage 6 - 10g
Temperature Neutral
Taste Bitter, Sour
Organ Affinity Kidneys, Liver

Role in Ren Shen Lu Rong Tang

Strengthens the Liver and Kidneys, fortifies the sinews and bones, and guides the formula's actions downward to the lower back and lower extremities.
Dong Chong Xia Cao

Dong Chong Xia Cao

Cordyceps

Dosage 3 - 6g
Temperature Warm
Taste Sweet
Organ Affinity Kidneys, Lungs

Role in Ren Shen Lu Rong Tang

Tonifies Kidney Yang and Lung Yin simultaneously, replenishes essence, and augments Qi. Uniquely addresses both Yang deficiency and potential Yin damage from warming herbs.
Long Yan Rou

Long Yan Rou

Longans

Dosage 6 - 10g
Temperature Warm
Taste Sweet
Organ Affinity Heart, Spleen

Role in Ren Shen Lu Rong Tang

Nourishes Blood, calms the spirit, and supplements the Heart and Spleen. Addresses the insomnia, poor memory, and palpitations that accompany severe Qi and Blood deficiency.
Wu Wei Zi

Wu Wei Zi

Schisandra berries

Dosage 3 - 6g
Temperature Warm
Taste Sour, Sweet
Organ Affinity Heart, Kidneys, Lungs

Role in Ren Shen Lu Rong Tang

Astringes Kidney essence and Lung Qi, generates fluids, and calms the spirit. Prevents the supplemented Qi and essence from leaking or dispersing, anchoring the formula's tonic effects.
Fu Ling

Fu Ling

Poria-cocos mushrooms

Dosage 6 - 10g
Temperature Neutral
Taste Sweet
Organ Affinity Heart, Kidneys, Lungs, Spleen

Role in Ren Shen Lu Rong Tang

Strengthens the Spleen, promotes water metabolism, and calms the spirit. Ensures the heavy, rich tonic herbs are properly absorbed without generating Dampness.
Huang Qi

Huang Qi

Milkvetch roots

Dosage 3 - 6g
Temperature Warm
Taste Sweet
Organ Affinity Lungs, Spleen

Role in Ren Shen Lu Rong Tang

Clears Deficiency-Heat from the Kidneys and drains Damp-Heat from the lower burner. Included as a restraining assistant to prevent the formula's many warming herbs from generating pathological Heat, and to protect Kidney Yin.
Envoy — Directs the formula to its target
Xiang Fu

Xiang Fu

Coco-grass rhizomes

Dosage 6 - 9g
Temperature Neutral
Taste Bitter, Pungent, Sweet
Organ Affinity Liver, Spleen, San Jiao (Triple Burner)

Role in Ren Shen Lu Rong Tang

Moves Qi and regulates the Liver. Prevents the many heavy, cloying tonic herbs from causing Qi stagnation, ensuring smooth flow and proper absorption of all the supplementing ingredients.

Why This Combination Works

How the herbs in Ren Shen Lu Rong Tang complement each other

Overall strategy

This formula addresses a complex pattern of Kidney essence (Jing) depletion combined with Qi and Blood deficiency. The strategy is to simultaneously warm and restore Kidney Yang and essence from below while reinforcing the Spleen's Qi and Blood-generating capacity from the middle, creating a comprehensive restoration of the body's foundational resources.

King herbs

Ren Shen (Ginseng) and Lu Rong (Deer Antler Velvet) form a powerful pair that addresses the two core deficiencies at once. Ren Shen powerfully replenishes the original Qi and strengthens the Spleen and Lungs, the organs responsible for generating and distributing Qi and Blood throughout the body. Lu Rong is among the strongest substances for warming Kidney Yang, replenishing essence, and strengthening bones and sinews. Together they represent the formula's dual action on both the Kidney foundation and the Spleen-Lung Qi mechanism.

Deputy herbs

Huang Qi reinforces Ren Shen's Qi-tonifying power, especially in raising Yang Qi and consolidating the exterior to prevent further leakage of vital substances. Dang Gui is the primary Blood-nourishing herb, ensuring that as Qi is restored, Blood production keeps pace, since Qi and Blood are mutually dependent.

Assistant herbs

Several assistants reinforce the King herbs from different angles. Ba Ji Tian, Bu Gu Zhi, Tu Si Zi, and Du Zhong all support Lu Rong in warming and stabilizing Kidney Yang, with each bringing slightly different strengths: Ba Ji Tian strengthens sinews, Bu Gu Zhi warms the Ming Men fire, Tu Si Zi gently nourishes both Yin and Yang, and Du Zhong specifically targets the lower back. Niu Xi directs the formula's actions to the lower body. Dong Chong Xia Cao is a unique addition that tonifies both Yang and Yin. Long Yan Rou and Wu Wei Zi address the Heart and spirit, calming palpitations and securing essence. Fu Ling supports the Spleen to ensure the heavy tonic herbs are properly absorbed. Huang Bai serves as a restraining assistant, its cold and bitter nature preventing the many warm herbs from generating pathological Heat and protecting residual Kidney Yin.

Envoy herbs

Xiang Fu serves as the formula's traffic controller, moving Liver Qi to prevent the many heavy, rich tonifying herbs from causing stagnation. Without this Qi-regulating action, the cloying nature of the tonics could obstruct digestion and Qi flow.

Notable synergies

The Ren Shen and Lu Rong pairing is the formula's signature combination, simultaneously building Qi and warming essence. The inclusion of Huang Bai among so many warming herbs is a sophisticated balancing strategy, preventing the formula from overshooting into excessive Heat while protecting Yin. The combination of Wu Wei Zi with the tonics creates an "astringent net" that holds in the supplemented Qi and essence.

How to Prepare

Traditional preparation instructions for Ren Shen Lu Rong Tang

When prepared as a decoction, add the herbs to approximately 800 ml of water. Bring to a boil, then reduce to a gentle simmer for 40–50 minutes. Strain and divide the liquid into two portions for morning and evening consumption. Lu Rong (Deer Antler Velvet) should ideally be ground into fine powder and dissolved into the strained decoction (or taken separately with the warm liquid), as it dissolves better this way than through prolonged boiling. This formula is more commonly encountered in honey pill (Wan) form as a patent medicine.

Common Modifications

How practitioners adapt Ren Shen Lu Rong Tang for specific situations

Added
Rou Gui

3-6g, to powerfully warm the Ming Men fire and promote circulation

Lai Fu Zi

3-6g (processed), to rescue depleted Yang and warm all channels

When Yang deficiency is severe with marked cold signs, adding Rou Gui and processed Fu Zi intensifies the formula's Yang-warming capacity to address more extreme cold patterns.

Educational content — always consult a qualified healthcare provider or TCM practitioner before using any herbal formula.

Contraindications

Situations where Ren Shen Lu Rong Tang should not be used or requires extra caution

Avoid

Yin deficiency with Heat signs (five-centre heat, night sweats, dry mouth, red tongue with little coating). The strongly warming nature of this formula would further deplete Yin and aggravate internal Heat.

Avoid

Active external pathogen invasion (common cold, flu, fever). Tonifying formulas can trap the pathogen inside the body and worsen the infection.

Avoid

Stomach Fire or Lung Heat with thick yellow phlegm. The warming tonics in this formula, especially Lu Rong, can intensify internal Heat and make phlegm thicker.

Caution

Hypertension or a tendency toward high blood pressure. Lu Rong and Ren Shen can raise blood pressure, and this formula should only be used under close medical supervision in such cases.

Caution

Liver Yang rising with symptoms like headache, dizziness, irritability, and flushed face. The ascending and warming nature of this formula can aggravate these symptoms.

Caution

Hormone-sensitive conditions such as breast cancer, uterine fibroids, or prostate disorders. Lu Rong contains small amounts of hormonal compounds that may stimulate hormone-sensitive tissues.

Special Populations

Important considerations for pregnancy, breastfeeding, and pediatric use

Pregnancy

Use with caution during pregnancy. Lu Rong (Deer Antler Velvet) contains trace amounts of hormonal compounds including estrogen-like substances and growth factors, which raise theoretical concerns for fetal development. Ren Shen (Ginseng) has also been flagged in some animal studies for potential effects on fetal development when used at high doses. The strongly warming and Yang-tonifying nature of this formula may also be unsuitable during pregnancy, when the body's Yin-Blood resources are already being directed toward the fetus. Pregnant women should consult a qualified practitioner before use, and this formula should generally be avoided unless specifically prescribed for a diagnosed condition of severe Yang deficiency threatening the pregnancy.

Breastfeeding

Caution is advised during breastfeeding. Lu Rong contains trace hormonal compounds (including estrogen-like substances) that could theoretically transfer through breast milk, though no definitive studies have confirmed harm. Ren Shen is generally considered safe in moderate doses, but the NCCIH notes that some experts recommend against ginseng use during breastfeeding due to insufficient safety data. The warming and tonifying nature of the formula could also potentially affect the quality or composition of breast milk. If used postpartum for severe deficiency and exhaustion, it should be under the guidance of a qualified practitioner, starting with lower doses and monitoring the infant for any signs of irritability, digestive upset, or flushing.

Children

This formula is generally not appropriate for children. Its strongly warming and Yang-tonifying properties are unsuitable for the immature constitutions of young children, who tend toward excess Yang and Heat. Lu Rong in particular contains trace hormonal compounds that could interfere with normal development. The formula should not be given to children under 12. For adolescents aged 12 and above with confirmed Kidney Yang or Essence deficiency (such as delayed development), a practitioner may consider significantly reduced doses (typically one-third to one-half of the adult dose), but only under professional supervision. Alternative, gentler tonifying approaches are generally preferred for pediatric patients.

Drug Interactions

If you are taking pharmaceutical medications, be aware of these potential interactions with Ren Shen Lu Rong Tang

Anticoagulants (e.g. warfarin): Ren Shen (Ginseng) has been reported in studies to potentially decrease the effectiveness of warfarin by reducing INR values. Lu Rong (Deer Antler Velvet) may conversely have mild anticoagulant properties. The combination creates unpredictable effects on coagulation, and concurrent use with blood thinners should be closely monitored or avoided.

Diabetes medications (insulin, oral hypoglycemics): Ren Shen may lower blood sugar levels and could enhance the effects of diabetes medications, increasing the risk of hypoglycemia. Blood glucose should be monitored more frequently if this formula is used alongside diabetes treatment.

Immunosuppressants (e.g. cyclosporine, tacrolimus): Ren Shen has immune-stimulating properties that could theoretically counteract immunosuppressive therapy. Patients on these medications should avoid this formula unless cleared by their physician.

Hormone therapies and oral contraceptives: Lu Rong contains trace amounts of sex hormones that could theoretically interact with hormone replacement therapy, oral contraceptives, or anti-estrogen medications used in breast cancer treatment.

Classical herbal contraindications: This formula should not be taken concurrently with Li Lu (Veratrum), Wu Ling Zhi (Pteropus droppings), or Zao Jia (Gleditsia), as these are traditional incompatibilities ("shi jiu" and "shi ba fan") of Ren Shen. Radish (Lai Fu Zi) and strong tea should also be avoided as they are traditionally said to diminish the efficacy of ginseng.

Usage Guidance

Practical advice for getting the most out of Ren Shen Lu Rong Tang

Best time to take

On an empty stomach, typically 30 minutes before meals in the morning and evening, or as directed by a practitioner.

Typical duration

Often taken as a course of 4 to 8 weeks, then reassessed by a practitioner. May be used cyclically (e.g. during winter months) for constitutional tonification.

Dietary advice

Avoid cold and raw foods (salads, iced drinks, raw fruit in excess) while taking this formula, as cold foods can impair the Spleen's digestive function and counteract the warming effects of the herbs. Avoid excessive tea consumption (especially green tea), as tea is traditionally held to reduce the potency of Ren Shen. Avoid radishes and turnips (Lai Fu Zi family), which are traditionally said to counteract ginseng's tonifying effect. Favor warm, easily digestible, nourishing foods such as congee, slow-cooked stews, lamb, bone broth, black beans, walnuts, and lightly cooked vegetables to support the formula's tonifying action. Avoid greasy, overly rich, or heavily fried foods, which can burden the Spleen and impair absorption of the formula.

Ren Shen Lu Rong Tang originates from Derived from the Cān Róng Wèi Shēng Wán (参茸卫生丸) tradition; standardized by Tóng Rén Táng (同仁堂) as a classical patent medicine formula Qīng dynasty, traditional patent medicine formulation

Classical Texts

Key passages from the classical Chinese medical texts that first described Ren Shen Lu Rong Tang and its clinical use

There are no specific classical quotes attributed to a single source text for Ren Shen Lu Rong Tang as a named formula. However, the therapeutic logic of combining Ren Shen and Lu Rong is grounded in well-established classical principles:

The Ben Cao Gang Mu (本草纲目) states regarding Lu Rong: 「生精补髓,养血益阳,强健筋骨。治一切虚损、耳聋、目暗、眩晕、虚痢。」 ("It generates Essence and supplements marrow, nourishes Blood and boosts Yang, strengthens sinews and bones. It treats all forms of vacuity detriment, deafness, dim vision, dizziness, and vacuity dysentery.")

Regarding Ren Shen, classical texts consistently describe its ability to 「大补元气」 ("greatly supplement the original Qi"). The pairing of Ren Shen with Lu Rong, known colloquially as "Shen Rong" (参茸), has long been regarded in the Chinese medical tradition as the premier combination for restoring depleted Qi, Blood, and Kidney Essence in severe or chronic deficiency conditions.

Historical Context

How Ren Shen Lu Rong Tang evolved over the centuries — its origins, lineage, and place in the broader tradition of Chinese medicine

Ren Shen Lu Rong Tang (or its pill form, Ren Shen Lu Rong Wan) is not attributed to a single classical text in the way that many canonical formulas are. Rather, it represents a longstanding tradition of combining Ren Shen (Ginseng) and Lu Rong (Deer Antler Velvet), the two most prized tonic substances in Chinese medicine, collectively known as "Shen Rong" (参茸). This pairing has been a cornerstone of tonifying practice for centuries, appearing across numerous medical texts and folk traditions.

The formula became widely available as a patent medicine (zhong cheng yao) during the modern era, produced by manufacturers such as Beijing Tong Ren Tang. Various manufacturers have created slightly different compositions, but all share the core of Ren Shen and Lu Rong supported by Kidney-tonifying and Blood-nourishing auxiliaries like Du Zhong, Dang Gui, Huang Qi, Ba Ji Tian, Bu Gu Zhi, Tu Si Zi, and Dong Chong Xia Cao. The formula reflects the broader tradition of comprehensive tonifying prescriptions that emerged during the Ming and Qing dynasties, when elaborate tonic formulas combining precious animal and plant ingredients became popular among the literati and imperial court.

The related formula Gui Ling Ji (龟龄集), recorded in 1541 and originally made for Ming Dynasty Emperor Jia Jing, similarly combines Lu Rong and Ren Shen as its core and represents the same therapeutic philosophy of simultaneously replenishing Qi, Blood, Essence, and Yang.