Dan Dao Qu Hui Tang

Drive Roundworms from the Biliary Tract Decoction · 胆道驱蛔汤

Also known as: Biliary Ascariasis Decoction, Gallbladder Tract Roundworm-Expelling Decoction

A modern antiparasitic formula designed to expel roundworms from the bile ducts. It combines herbs that calm and paralyse roundworms with herbs that move Qi, relieve pain, and promote their expulsion through the intestines. It is primarily used for biliary ascariasis, a condition where roundworms migrate into the biliary tract causing severe colicky upper abdominal pain, nausea, and vomiting.

Origin Zhōng Xī Yī Jié Hé Zhì Liáo Jí Fù Zhèng (中西医结合治疗急腹症, Integrated Chinese-Western Medicine Treatment of Acute Abdominal Conditions) — Modern, 1970s CE
Composition 7 herbs
Wu Mei
King
Wu Mei
Bing Lang
Deputy
Bing Lang
Shi Jun Zi
Deputy
Shi Jun Zi
Ku Lian Pi
Assistant
Ku Lian Pi
Mu Xiang
Assistant
Mu Xiang
Zhi Ke
Assistant
Zhi Ke
Da Huang
Envoy
Da Huang
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Educational content Consult qualified TCM practitioners for diagnosis and treatment

Patterns Addressed

In TCM, symptoms don't appear randomly — they cluster into recognizable patterns of disharmony that reveal what's out of balance in the body. Dan Dao Qu Hui Tang is designed to correct these specific patterns.

Why Dan Dao Qu Hui Tang addresses this pattern

When roundworms migrate from the intestine into the biliary tract, they obstruct normal bile flow and cause intense spasmodic pain in the upper abdomen that often radiates to the back. This pattern presents with sudden onset of severe drilling pain below the right ribs or in the epigastrium, accompanied by nausea, vomiting (sometimes containing roundworms), and a sensation of something moving in the abdomen. The formula addresses this pattern by using Wu Mei's sour nature to calm the worms and relieve spasm, Bing Lang and Shi Jun Zi to kill the parasites, Ku Lian Pi to clear Heat from the infection, Mu Xiang and Zhi Ke to regulate Qi and stop pain, and Da Huang to purge the dead worms from the intestines.

A practitioner would look for one or more of these signs

Abdominal Pain

Sudden, severe boring or colicky pain in the upper right abdomen or epigastrium

Nausea

Nausea and vomiting, sometimes with worm fragments visible in vomitus

Epigastric Fullness And Pain Relieved By Vomiting

Vomiting of clear fluid or bile, may contain roundworms

Abdominal Distention

Abdominal bloating between episodes of colic

Cold Extremities

Cold hands and feet during acute colic episodes

Commonly Prescribed For

These conditions can arise from the patterns above. A practitioner would consider Dan Dao Qu Hui Tang when these conditions are specifically caused by those patterns — not for all cases of these conditions.

Arises from: Roundworms in the Bile Duct (Hui Jue)

TCM Interpretation

In TCM, biliary ascariasis is understood as a disruption caused by parasites (Hui Chong, 蛔虫) migrating upward into the Gallbladder and Liver channel system. The severe, boring pain reflects intense Qi stagnation caused by physical obstruction of the bile duct. The vomiting reflects rebellious Stomach Qi forced upward by the blockage. The cold extremities during acute attacks represent Qi and Yang being obstructed in the centre, unable to reach the limbs. Because roundworms are known to be 'averse to sour and fond of sweet' (Hui De Suan Ze Fu), the classical approach uses sour flavours to calm them and sweet flavours to lure them from hiding.

Why Dan Dao Qu Hui Tang Helps

Dan Dao Qu Hui Tang directly addresses each aspect of biliary ascariasis. Wu Mei's intensely sour nature exploits the roundworm's aversion to acidity, causing them to relax and retreat from the bile duct. Bing Lang and Shi Jun Zi then kill the dislodged worms while promoting their downward passage. Ku Lian Pi provides additional vermicidal action and clears the Heat that develops from the infection. Mu Xiang and Zhi Ke relieve the severe colicky pain by moving stagnant Qi in the Liver and Gallbladder channels. Finally, Da Huang purges the dead worms out through the stool, completing the treatment cycle from calming to killing to expelling.

Also commonly used for

Cholecystitis

When secondary to parasitic obstruction of the biliary tract

Cholangitis

When caused by or complicated by ascariasis

Abdominal Pain

Acute colicky abdominal pain from parasitic causes

What This Formula Does

Every TCM formula has a specific set of actions — here's what Dan Dao Qu Hui Tang does in the body, explained in both everyday and TCM terms

Therapeutic focus

In practical terms, Dan Dao Qu Hui Tang is primarily used to support these areas of health:

TCM Actions

In TCM terminology, these are the specific therapeutic actions that Dan Dao Qu Hui Tang performs to restore balance in the body:

How It Addresses the Root Cause

TCM doesn't just suppress symptoms — it aims to resolve the underlying imbalance. Here's how Dan Dao Qu Hui Tang works at the root level.

Biliary ascariasis (胆道蛔虫症) occurs when roundworms (Ascaris lumbricoides), normally residing in the intestines, migrate upward through the sphincter of Oddi and enter the bile duct. In TCM terms, this condition involves a disruption of the Liver and Gallbladder's smooth flow of Qi. The worms are a tangible pathogenic factor (虫积) that physically obstructs the biliary passages, causing the Liver and Gallbladder Qi to stagnate severely. This produces the hallmark symptom: sudden, excruciating pain below the right ribcage (right hypochondriac region), often described as drilling or boring in character, which comes and goes in waves as the worm moves.

The disease mechanism typically involves an underlying pattern of intestinal cold mixed with upper heat (上热下寒). When the intestinal environment becomes inhospitable to the worms — often due to cold in the intestines or heat in the upper digestive tract — the worms become restless and migrate upward, seeking a warmer environment. This "fleeing" behavior is what drives them into the bile duct. As the worms irritate the biliary tract, they cause spasm and inflammation, which can lead to secondary Damp-Heat accumulation in the Liver and Gallbladder, producing symptoms like fever, jaundice, nausea, and vomiting. The Stomach Qi rebels upward (causing vomiting, sometimes with visible worms), while the Liver and Gallbladder lose their ability to ensure smooth Qi flow.

Dan Dao Qu Hui Tang addresses this mechanism on multiple fronts: it uses sour-flavored herbs to calm the restless worms (since roundworms become still when exposed to sourness), antiparasitic herbs to kill and expel the worms from the biliary tract, and Qi-regulating herbs to restore smooth flow through the Liver and Gallbladder system, thereby relieving the intense colicky pain.

Formula Properties

Every formula has an inherent temperature, taste, and affinity for specific organs — these properties determine how it interacts with the body

Overall Temperature

Slightly Cool

Taste Profile

Predominantly sour and bitter with pungent notes — sour to calm the worms, bitter to kill and expel them downward, pungent to move stagnant Qi and relieve pain.

Ingredients

7 herbs

The herbs that make up Dan Dao Qu Hui Tang, organized by their role in the prescription

King — Main ingredient driving the formula
Deputy — Assists and enhances the King
Assistant — Supports or moderates other herbs
Envoy — Directs the formula to its target
King — Main ingredient driving the formula
Wu Mei

Wu Mei

Chinese plums

Dosage 15 - 30g
Temperature Neutral
Taste Sour
Organ Affinity Large Intestine, Liver, Lungs, Spleen

Role in Dan Dao Qu Hui Tang

The sour and astringent nature of Wu Mei calms and paralyses roundworms (an hui). Roundworms are averse to sour substances, so Wu Mei causes them to relax and retract from the bile duct back into the intestinal lumen, providing immediate relief from biliary colic. This is the critical first step in treatment.
Deputies — Assists and enhances the King
Bing Lang

Bing Lang

Areca nuts

Dosage 15 - 30g
Temperature Warm
Taste Bitter, Pungent
Organ Affinity Large Intestine, Stomach

Role in Dan Dao Qu Hui Tang

Bing Lang is the primary vermicidal herb in this formula. It kills and paralyses roundworms, and its descending action promotes their downward movement through the intestines for expulsion. It also moves Qi and reduces accumulation.
Shi Jun Zi

Shi Jun Zi

Quisqualis fruits

Dosage 12 - 20g
Temperature Warm
Taste Sweet
Organ Affinity Spleen, Stomach

Role in Dan Dao Qu Hui Tang

Shi Jun Zi is a classical antiparasitic herb with a sweet taste that roundworms are attracted to. It kills intestinal parasites, particularly roundworms, and also aids digestion. Its sweet and warm nature complements Wu Mei's sour quality, combining attraction and paralysis of the worms.
Assistants — Supports or moderates other herbs
Ku Lian Pi

Ku Lian Pi

Chinaberry root barks

Dosage 9 - 15g
Temperature Cold
Taste Bitter
Organ Affinity Spleen, Stomach, Liver

Role in Dan Dao Qu Hui Tang

Ku Lian Pi is a powerful vermicide that kills roundworms. Its bitter and cold nature clears Heat that may have accumulated from the parasitic infection and associated inflammation in the biliary tract. It reinforces the antiparasitic action of Bing Lang and Shi Jun Zi.
Mu Xiang

Mu Xiang

Costus roots

Dosage 6 - 10g
Temperature Warm
Taste Bitter, Pungent
Organ Affinity Gallbladder, Large Intestine, Liver, Lungs, Spleen, Stomach

Role in Dan Dao Qu Hui Tang

Mu Xiang moves Qi and relieves pain in the abdomen. Biliary ascariasis causes severe spasmodic pain from Qi stagnation in the Liver and Gallbladder. Mu Xiang's Qi-regulating action alleviates this pain and helps coordinate intestinal peristalsis to promote worm expulsion.
Zhi Ke

Zhi Ke

Bitter oranges

Dosage 9 - 12g
Temperature Warm
Taste Bitter, Pungent, Sour
Organ Affinity Spleen, Stomach

Role in Dan Dao Qu Hui Tang

Zhi Ke regulates Qi flow and relieves distension. It promotes the downward movement of Qi in the gastrointestinal tract, working synergistically with Mu Xiang to relieve abdominal bloating and pain, and with Bing Lang to drive the paralysed worms downward for expulsion.
Envoy — Directs the formula to its target
Da Huang

Da Huang

Rhubarb

Dosage 6 - 9g
Temperature Cold
Taste Bitter
Organ Affinity Spleen, Stomach, Large Intestine, Liver, Pericardium
Preparation May be added in the last 5 minutes of decoction (后下) to preserve its purgative effect when strong bowel-clearing action is desired.

Role in Dan Dao Qu Hui Tang

Da Huang purges the bowels and drains downward. It serves as the envoy by directing the entire formula's action downward through the intestines, ensuring the paralysed and killed roundworms are physically expelled from the body via the stool. It also clears Heat-toxin from the infection.

Why This Combination Works

How the herbs in Dan Dao Qu Hui Tang complement each other

Overall strategy

Biliary ascariasis occurs when roundworms migrate from the intestine into the bile duct, causing severe colicky pain, nausea, and vomiting. The formula's strategy is threefold: first calm the worms to relieve acute spasm and pain, then kill them, and finally drive them out of the body. This sequence (calm, kill, expel) is essential because active worms burrow deeper when agitated.

King herbs

Wu Mei (Smoked Plum) is the King herb. Its intensely sour flavour exploits a well-known property of roundworms: they recoil from acidity. When roundworms in the bile duct encounter the sour environment created by Wu Mei, they relax their grip and retreat back into the intestinal lumen. This immediately relieves the acute biliary spasm and makes the worms accessible for killing and expulsion by the other herbs.

Deputy herbs

Bing Lang and Shi Jun Zi are the Deputy herbs responsible for the vermicidal action. Bing Lang paralyses the worms' musculature and promotes their downward movement, while Shi Jun Zi provides additional antiparasitic killing power. Together, they ensure the worms that Wu Mei has dislodged are neutralised before expulsion.

Assistant herbs

Ku Lian Pi is a reinforcing Assistant that adds a third layer of antiparasitic action while clearing Heat from the infection. Mu Xiang and Zhi Ke are counteracting Assistants that address the secondary symptoms of Qi stagnation, abdominal distension and pain that accompany biliary ascariasis. By moving Qi and relieving spasm, they provide symptomatic relief while also promoting intestinal motility to assist worm expulsion.

Envoy herbs

Da Huang serves as the Envoy, directing the entire formula's action downward. Its purgative effect ensures that the paralysed or dead roundworms are physically flushed out through the bowels. It also clears any accumulated Heat-toxin resulting from the infection and inflammation.

Notable synergies

The Wu Mei and Bing Lang pairing is the core synergy: Wu Mei calms and paralyses the worms (making them release their grip), while Bing Lang kills and propels them downward. Neither herb alone achieves both effects. The Mu Xiang and Zhi Ke pairing provides complementary Qi-moving action, one aromatic and warming (Mu Xiang) and the other descending and clearing (Zhi Ke), together covering both the pain and distension of biliary obstruction.

How to Prepare

Traditional preparation instructions for Dan Dao Qu Hui Tang

Add herbs to approximately 600 ml of water. Bring to a boil and then simmer for 30 minutes. Strain and divide the decoction into 2 portions. Take warm, twice daily. During treatment, avoid greasy and oily foods, as these can stimulate roundworm activity. For acute biliary colic, the decoction may be taken in small, frequent sips to avoid triggering vomiting.

Common Modifications

How practitioners adapt Dan Dao Qu Hui Tang for specific situations

Added
Ban Xia

9-12g, to descend rebellious Stomach Qi and stop vomiting

Sheng Jiang

6-9g, to harmonise the Stomach and reduce nausea

Acute biliary ascariasis frequently causes severe vomiting that may prevent the patient from keeping the decoction down. Ban Xia and Sheng Jiang descend rebellious Stomach Qi and stop vomiting, allowing the formula to be retained and absorbed.

Educational content — always consult a qualified healthcare provider or TCM practitioner before using any herbal formula.

Contraindications

Situations where Dan Dao Qu Hui Tang should not be used or requires extra caution

Avoid

Pregnancy. Several herbs in this formula (Ku Lian Pi/苦楝皮, Bing Lang/槟榔, Da Huang if added) have known toxicity or uterine-stimulating properties and are contraindicated during pregnancy.

Caution

Severely debilitated or Qi-deficient patients. The formula's antiparasitic herbs are strongly draining and purgative in nature. In weak patients, the formula should be combined with tonifying herbs (such as Si Jun Zi Tang) or the patient should be stabilized first before aggressive parasite expulsion.

Avoid

Complete biliary or intestinal obstruction requiring surgical intervention. If there are signs of peritonitis, perforation, or complete mechanical obstruction (rigid abdomen, metallic bowel sounds, absent bowel sounds), herbal treatment alone is insufficient and surgical consultation is mandatory.

Caution

Patients with liver or kidney impairment. Ku Lian Pi (苦楝皮, Chinaberry root bark) contains hepatotoxic alkaloids and should not be used in patients with pre-existing liver disease. Dosages must be carefully controlled.

Caution

Use with caution in young children under 3 years. Antiparasitic herbs such as Ku Lian Pi and Bing Lang require strict dosage control in pediatric patients due to potential toxicity.

Special Populations

Important considerations for pregnancy, breastfeeding, and pediatric use

Pregnancy

Contraindicated during pregnancy. Ku Lian Pi (苦楝皮, Chinaberry root bark) is toxic and traditionally prohibited in pregnancy. Bing Lang (槟榔, Areca seed) promotes downward movement and can stimulate intestinal and uterine contractions. If Da Huang (大黄, Rhubarb) is added for constipation (a common modification), it further increases the risk of miscarriage. Pregnant women with biliary ascariasis should be managed with safer alternatives under close medical supervision.

Breastfeeding

Use with caution during breastfeeding. Ku Lian Pi (苦楝皮) contains toosendanin and other alkaloids with known toxicity, and it is unclear how much passes into breast milk. Bing Lang (槟榔) contains arecoline, a cholinergic alkaloid that could potentially transfer into breast milk and affect the nursing infant. If the formula is medically necessary for the breastfeeding mother, temporary cessation of breastfeeding during treatment (typically 2–3 days) should be considered, with pumping and discarding of milk during that period. A practitioner experienced in herbal safety should supervise any use during lactation.

Children

Biliary and intestinal ascariasis historically occurred most commonly in children, making pediatric use of antiparasitic formulas clinically important. However, strict dosage adjustments are essential: - Ku Lian Pi (苦楝皮) is the most toxic herb in the formula. The standard adult dried dosage is 10–15g; pediatric dosage must be carefully reduced and should not exceed recommended guidelines. Fresh Ku Lian Pi should not exceed 30g even in adults. This herb should not be given to children under 3 years old. - Shi Jun Zi (使君子) has a traditional pediatric dosing guideline: 1–2 seeds per year of age (e.g., a 5-year-old takes 5–10 seeds), not exceeding 20 seeds maximum. It should be taken on an empty stomach in the morning. If hiccupping occurs after ingestion, the herb should be stopped. Shi Jun Zi should not be taken with hot soup or hot food. - Bing Lang (槟榔) dosage should be proportionally reduced for children. - Overall formula dosage for children aged 3–6 is typically one-third to one-half the adult dose; for children aged 7–14, approximately half to two-thirds the adult dose. - Treatment duration should be kept short (2–3 days for acute management), and children should be monitored closely for signs of toxicity (nausea, vomiting, dizziness, abdominal pain worsening).

Drug Interactions

If you are taking pharmaceutical medications, be aware of these potential interactions with Dan Dao Qu Hui Tang

Arecoline interactions (from Bing Lang/槟榔): Bing Lang contains arecoline, a parasympathomimetic alkaloid. It may potentiate the effects of cholinergic drugs, acetylcholinesterase inhibitors (e.g., donepezil, rivastigmine), and other parasympathomimetic agents, potentially causing excessive salivation, bradycardia, or gastrointestinal distress. It may also antagonize anticholinergic medications (e.g., atropine, scopolamine). Note that atropine is sometimes used in the Western medical management of biliary colic from ascariasis, so concurrent use requires coordination.

Toosendanin interactions (from Ku Lian Pi/苦楝皮): Ku Lian Pi contains toosendanin and other alkaloids with hepatotoxic potential. It should not be combined with other hepatotoxic drugs (e.g., acetaminophen/paracetamol in high doses, statins, methotrexate, certain antifungals). Liver function should be monitored if concurrent use of any potentially hepatotoxic medication is unavoidable.

Anthelmintic drug interactions: If modern anthelmintic drugs (albendazole, mebendazole, praziquantel) are being used concurrently, the combined antiparasitic effect may be unpredictable. It is generally advisable to use herbal and pharmaceutical anthelmintics sequentially rather than simultaneously.

Usage Guidance

Practical advice for getting the most out of Dan Dao Qu Hui Tang

Best time to take

Traditionally taken on an empty stomach in the morning for maximum antiparasitic effect, with a second dose in the late afternoon if prescribed twice daily.

Typical duration

Acute use: 2–4 days for the acute biliary colic phase, followed by a separate course of 2–3 days of dedicated antiparasitic treatment once pain has subsided.

Dietary advice

Avoid greasy, oily, and fatty foods during treatment, as these can stimulate bile secretion and potentially aggravate biliary spasm and worm activity. Avoid raw, cold foods and cold beverages, which may worsen intestinal cold and further agitate the roundworms. Avoid sweet and sugary foods, as roundworms are traditionally believed to be attracted to sweetness. Light, easily digestible, warm foods such as rice porridge and steamed vegetables are recommended. Shi Jun Zi (使君子) specifically must not be taken with hot soup or hot food, as this combination can cause hiccupping and nausea. Resume a normal diet gradually after the acute episode has resolved and worms have been expelled.

Dan Dao Qu Hui Tang originates from Zhōng Xī Yī Jié Hé Zhì Liáo Jí Fù Zhèng (中西医结合治疗急腹症, Integrated Chinese-Western Medicine Treatment of Acute Abdominal Conditions) Modern, 1970s CE

Classical Texts

Key passages from the classical Chinese medical texts that first described Dan Dao Qu Hui Tang and its clinical use

This formula originates from the modern integrative medicine text Zhong Xi Yi Jie He Zhi Liao Ji Fu Zheng (《中西医结合治疗急腹症》, Integrated Chinese-Western Medicine Treatment of Acute Abdominal Conditions), rather than from a classical pre-modern source. As such, it does not have classical literary quotes in the traditional sense.

However, the principle of treating roundworm disease through a combination of sour, bitter, and pungent flavors draws directly from the classical understanding expressed in the Shang Han Lun (《伤寒论》) discussion of Wu Mei Wan (乌梅丸): 「蛔得酸则静,得辛则伏,得苦则下」"Roundworms become calm when they encounter sourness, retreat when they encounter pungency, and descend when they encounter bitterness." This classical principle underpins the flavor strategy of Dan Dao Qu Hui Tang, which uses sour Wu Mei to calm the worms, pungent and bitter antiparasitic herbs to kill and expel them.

The National TCM Master Deng Tietao (邓铁涛) recorded a closely related formula called Dan Hui Tang (胆蛔汤) among his 62 experience formulas, described with the actions: 「驱虫,安蛔,止痛」"Expel worms, calm roundworms, relieve pain."

Historical Context

How Dan Dao Qu Hui Tang evolved over the centuries — its origins, lineage, and place in the broader tradition of Chinese medicine

Dan Dao Qu Hui Tang is a modern formula developed during the integrative Chinese-Western medicine (中西医结合) movement in China, primarily documented in Zhong Xi Yi Jie He Zhi Liao Ji Fu Zheng (《中西医结合治疗急腹症》, Integrated Chinese-Western Medicine Treatment of Acute Abdominal Conditions). This influential text emerged from large-scale clinical collaborations in Chinese hospitals during the 1960s–1970s, where TCM and Western surgical teams worked together to manage acute surgical emergencies using combined approaches. Biliary ascariasis was extremely common in rural China at that time and represented an important area where TCM formulas could provide rapid, effective non-surgical treatment.

The formula draws upon centuries of accumulated knowledge about antiparasitic herbs. The classical foundation for treating roundworm disease comes from Zhang Zhongjing's Wu Mei Wan (乌梅丸) in the Shang Han Lun (circa 200 CE), which established the principle of using sour, bitter, and pungent flavors together to manage roundworms. Over subsequent dynasties, specialized antiparasitic formulas such as Hua Chong Wan (化虫丸), Bu Dai Wan (布袋丸), and various "Qu Hui" (驱蛔, expel roundworm) formulas were developed. National TCM Master Deng Tietao (邓铁涛) recorded a closely related formula called Dan Hui Tang (胆蛔汤) among his famous 62 experience formulas, with the composition of stir-fried Fei Zi (榧子), Shi Jun Zi (使君子), Bing Lang (槟榔), Wu Mei (乌梅), and Ku Lian Gen Bai Pi (苦楝根白皮).

With the advent of modern anthelmintic drugs (such as albendazole and mebendazole) and improved sanitation, biliary ascariasis has become far less common in developed regions. The formula's clinical use has correspondingly decreased, though it remains relevant in areas where parasitic infections persist and as a model of how TCM integrative approaches can effectively manage acute abdominal emergencies.