Bi Xie Shen Shi Tang

Dioscorea Decoction to Leach Out Dampness · 萆薢渗湿汤

Also known as: Bei Xie Shen Shi Tang, Dioscorea Hypoglauca Decoction to Overcome Dampness

A classical formula designed to clear damp-heat from the lower body, cool the blood, and promote urination. It is commonly used for skin conditions such as eczema, leg ulcers, and lower limb redness and swelling caused by dampness and heat accumulating in the lower part of the body.

Origin Yang Ke Xin De Ji · Bu Yi (疡科心得集·补遗) by Gao Bingjun (高秉钧) — Qīng dynasty, 1805 CE
Composition 8 herbs
Bi Xie
King
Bi Xie
Yi Yi Ren
Deputy
Yi Yi Ren
Chi Fu Ling
Deputy
Chi Fu Ling
Hua Shi
Deputy
Hua Shi
Huang Qi
Assistant
Huang Qi
Mu Dan Pi
Assistant
Mu Dan Pi
Ze Xie
Assistant
Ze Xie
Tong Cao
Envoy
Tong Cao
Explore composition

Educational content Consult qualified TCM practitioners for diagnosis and treatment

Patterns Addressed

In TCM, symptoms don't appear randomly — they cluster into recognizable patterns of disharmony that reveal what's out of balance in the body. Bi Xie Shen Shi Tang is designed to correct these specific patterns.

Why Bi Xie Shen Shi Tang addresses this pattern

This is the primary pattern the formula was designed to address. When damp-heat accumulates in the lower body, it can obstruct the channels and waterways, leading to skin lesions, sores, and swelling in the lower limbs. The dampness causes weeping, oozing discharge from skin lesions, while the heat produces redness, burning sensations, and inflammation. Bi Xie, the King herb, directly drains this downward-pouring dampness, while Huang Bai targets the heat component specifically in the lower body. The Deputy herbs (Yi Yi Ren, Chi Fu Ling, Hua Shi) reinforce the drainage of damp-heat through urination, and Mu Dan Pi cools the blood-level heat that manifests as red, inflamed skin. The entire formula works as a coordinated system to give damp-heat an exit route through the Bladder.

A practitioner would look for one or more of these signs

Eczema

Acute weeping eczema with red, oozing lesions, especially on the lower body

Ulcer

Chronic leg ulcers (臁疮) with discharge and surrounding redness

Cellulitis

Lower limb redness, swelling, heat, and pain (erysipelas/丹毒)

Cloudy Urine

Turbid or dark yellow urine

Thin Vaginal Discharge

Yellow, foul-smelling vaginal discharge from damp-heat

Commonly Prescribed For

These conditions can arise from the patterns above. A practitioner would consider Bi Xie Shen Shi Tang when these conditions are specifically caused by those patterns — not for all cases of these conditions.

Arises from: Damp-Heat

TCM Interpretation

In TCM, acute eczema with weeping, red, and itchy skin is understood as damp-heat lodging in the skin. The dampness causes the oozing and weeping of fluid from the lesions, while the heat produces the redness, burning sensation, and intense itching. When the Spleen's ability to transform fluids is weakened, dampness accumulates internally. If this dampness combines with heat (from diet, climate, or emotional factors), it spills outward to the skin surface, particularly affecting the lower body due to the downward-flowing nature of dampness. The yellow, greasy tongue coating and slippery, rapid pulse are hallmark signs of this damp-heat pattern.

Why Bi Xie Shen Shi Tang Helps

Bi Xie Shen Shi Tang addresses eczema by tackling the root cause of damp-heat from the inside. Bi Xie, the King herb, drains the accumulated dampness that causes the weeping and oozing of the skin lesions. Yi Yi Ren strengthens the Spleen to prevent further dampness from forming while also helping to clear pus and discharge. Huang Bai provides strong heat-clearing and detoxifying action that reduces the inflammatory redness. Mu Dan Pi cools blood-level heat and improves circulation, helping to resolve the redness and promote healing of damaged skin. The diuretic herbs (Hua Shi, Ze Xie, Chi Fu Ling, Tong Cao) collectively channel the damp-heat out through urination, providing an internal drainage route that relieves pressure on the skin. Clinical studies have shown this formula to be effective for acute damp-heat type eczema, with reported efficacy rates around 89%.

Also commonly used for

Ulcer

Chronic leg ulcers (臁疮) with oozing discharge

Vaginitis

Fungal or bacterial vaginitis with damp-heat presentation

Erythema Nodosum

Nodular redness and swelling on the lower legs

Prostatitis

Chronic prostatitis with damp-heat in the lower Jiao

Urinary Tract Infection

Cystitis or urethritis with burning and turbid urine

Contact Dermatitis

Skin inflammation with weeping and itching from damp-heat

Deep Vein Thrombosis

Iliofemoral venous thrombosis with damp-heat obstruction

What This Formula Does

Every TCM formula has a specific set of actions — here's what Bi Xie Shen Shi Tang does in the body, explained in both everyday and TCM terms

Therapeutic focus

In practical terms, Bi Xie Shen Shi Tang is primarily used to support these areas of health:

TCM Actions

In TCM terminology, these are the specific therapeutic actions that Bi Xie Shen Shi Tang performs to restore balance in the body:

How It Addresses the Root Cause

TCM doesn't just suppress symptoms — it aims to resolve the underlying imbalance. Here's how Bi Xie Shen Shi Tang works at the root level.

This formula addresses conditions caused by Damp-Heat accumulating in the lower part of the body. In TCM theory, Dampness is a heavy, turbid, sticky pathological substance that tends to sink downward, much like water flows to the lowest point. When Dampness combines with Heat, it becomes particularly stubborn and difficult to resolve. This Damp-Heat lodges in the lower body, affecting the skin of the legs, the urogenital area, and the lower limbs.

The Spleen plays a central role in this pathomechanism. When the Spleen's ability to transport and transform fluids is impaired (from diet, climate, or constitutional weakness), Dampness accumulates internally. Over time, or combined with external exposure to damp and hot environments, this stagnant Dampness generates Heat. The resulting Damp-Heat pours downward, obstructing the channels and collaterals of the lower limbs, where it produces weeping skin lesions (such as leg ulcers known as lian chuang 臁疮), eczema with oozing and redness, lower leg erysipelas (丹毒), swelling, and inflammatory skin conditions. The tongue is typically red with a yellow, greasy coating, and the pulse is slippery and rapid, all confirming the presence of Damp-Heat.

Because Damp-Heat also enters the Blood level in this pattern, the skin lesions are not merely swollen but actively red, hot, and inflamed, sometimes with purplish discoloration. The Blood becomes heated and may stagnate locally, contributing to the persistent, hard-to-heal nature of these conditions. The formula therefore needs to address not only Dampness and Heat but also the Blood-level component of the pathology, which is why it includes herbs that cool and move Blood alongside the primary Dampness-draining strategy.

Formula Properties

Every formula has an inherent temperature, taste, and affinity for specific organs — these properties determine how it interacts with the body

Overall Temperature

Cool

Taste Profile

Predominantly bland and bitter — bland to drain Dampness through urination, bitter to dry Dampness and clear Heat.

Channels Entered

Ingredients

8 herbs

The herbs that make up Bi Xie Shen Shi Tang, organized by their role in the prescription

King — Main ingredient driving the formula
Deputy — Assists and enhances the King
Assistant — Supports or moderates other herbs
Envoy — Directs the formula to its target
King — Main ingredient driving the formula
Bi Xie

Bi Xie

Fish-poison yam

Dosage 12 - 15g
Temperature Neutral
Taste Bitter
Organ Affinity Urinary Bladder, Stomach, Liver

Role in Bi Xie Shen Shi Tang

The chief herb of the formula. Bi Xie drains dampness, separates the clear from the turbid, and resolves damp turbidity. It directly addresses the core pathomechanism of damp-heat pouring downward by promoting the excretion of dampness through urination, serving as the primary force to resolve the underlying dampness that fuels the condition.
Deputies — Assists and enhances the King
Yi Yi Ren

Yi Yi Ren

Job's tears

Dosage 15 - 30g
Temperature Cool
Taste Sweet
Organ Affinity Lungs, Spleen, Stomach

Role in Bi Xie Shen Shi Tang

Strengthens the Spleen and drains dampness through bland percolation. By supporting the Spleen's ability to transport and transform fluids, it helps address the root cause of dampness accumulation while reinforcing Bi Xie's dampness-draining action. It also clears heat and expels pus, which aids in resolving skin lesions with discharge.
Chi Fu Ling

Chi Fu Ling

Red poria

Dosage 9 - 15g
Temperature Neutral
Taste Sweet
Organ Affinity Kidneys

Role in Bi Xie Shen Shi Tang

Promotes urination and drains damp-heat specifically. Unlike white Poria (which primarily tonifies the Spleen), Chi Fu Ling (red Poria) is more directed toward clearing heat from the waterways and separating damp-heat, making it well-suited for conditions where dampness and heat are intertwined in the lower body.
Hua Shi

Hua Shi

Talc

Dosage 15 - 20g
Temperature Cold
Taste Sweet
Organ Affinity Urinary Bladder, Stomach
Preparation Wrap in cloth before decocting (包煎)

Role in Bi Xie Shen Shi Tang

Clears heat and promotes urination through its sweet, bland, and cold nature. It helps drain damp-heat downward and out through the urine, powerfully supporting the formula's strategy of giving dampness and heat an exit route via the Bladder.
Assistants — Supports or moderates other herbs
Huang Qi

Huang Qi

Milkvetch roots

Dosage 6 - 10g
Temperature Warm
Taste Sweet
Organ Affinity Lungs, Spleen

Role in Bi Xie Shen Shi Tang

Clears heat and dries dampness, particularly in the lower body. Huang Bai has a strong affinity for the Kidney and Bladder, making it especially effective at clearing damp-heat from the lower part of the body. It also has detoxifying properties that help resolve sores, ulcers, and skin lesions associated with toxic damp-heat.
Mu Dan Pi

Mu Dan Pi

Mudan peony bark

Dosage 6 - 10g
Temperature Cool
Taste Bitter, Pungent
Organ Affinity Heart, Kidneys, Liver

Role in Bi Xie Shen Shi Tang

Cools the blood, invigorates blood circulation, and clears heat. When damp-heat lingers, it can enter the blood level, causing redness, swelling, and skin lesions. Mu Dan Pi addresses this blood-level heat, reduces inflammation, and helps resolve blood stagnation that often accompanies chronic skin sores. It also clears residual heat from the Bladder and drains deficiency fire from the Kidney.
Ze Xie

Ze Xie

Water plantain

Dosage 6 - 10g
Temperature Cold
Taste Sweet
Organ Affinity Urinary Bladder, Kidneys

Role in Bi Xie Shen Shi Tang

Promotes urination and drains dampness from the lower body. It works alongside the Deputy herbs to ensure thorough elimination of accumulated fluids and heat through the urinary pathway, reinforcing the formula's overall drainage strategy.
Envoy — Directs the formula to its target
Tong Cao

Tong Cao

Tetrapanax piths

Dosage 3 - 6g
Temperature Cool
Taste Sweet
Organ Affinity Stomach, Lungs

Role in Bi Xie Shen Shi Tang

Opens the waterways and guides heat downward through the urinary tract. As the Envoy, Tong Cao directs the combined actions of the other herbs toward the Bladder, ensuring that damp-heat is channeled out through urination. Its light, bland nature makes it effective at opening passages and leading the formula's therapeutic action to the intended destination.

Why This Combination Works

How the herbs in Bi Xie Shen Shi Tang complement each other

Overall strategy

The formula addresses damp-heat that has poured downward and lodged in the lower body, manifesting as skin lesions, sores, redness, and swelling in the lower limbs. The treatment strategy follows the classical principle that "to treat dampness, one must promote urination" (治湿不利小便非其治也). The formula opens the urinary pathway to drain damp-heat downward and out, while simultaneously cooling the blood to address the inflammatory skin manifestations.

King herbs

Bi Xie serves as the sole King herb. Its primary action is to drain dampness and separate the clear from the turbid, directly targeting the core pathogenic factor of damp turbidity in the lower body. It promotes urination without being overly cold or harsh, making it a steady and effective lead herb for resolving dampness that has settled in the lower part of the body.

Deputy herbs

Yi Yi Ren, Chi Fu Ling, and Hua Shi form a trio that reinforces Bi Xie's dampness-draining action from multiple angles. Yi Yi Ren strengthens the Spleen to address the root of dampness production while also clearing heat and expelling pus from skin lesions. Chi Fu Ling specifically drains damp-heat through the urinary tract. Hua Shi powerfully clears heat and promotes urination, giving dampness and heat a clear exit route downward.

Assistant herbs

Huang Bai (restraining assistant) clears heat and dries dampness with a specific tropism for the lower body, adding a strong heat-clearing and detoxifying action that targets sores and ulcers. Mu Dan Pi (reinforcing assistant) cools the blood and invigorates blood circulation, addressing the blood-level heat and stagnation that produce the redness, swelling, and chronic skin damage seen in these conditions. Ze Xie (reinforcing assistant) further promotes urination and drains damp-heat, adding depth to the formula's drainage capacity.

Envoy herbs

Tong Cao serves as the Envoy, guiding heat downward through the waterways and opening the urinary passages. Its light, bland nature helps direct the combined force of all the other herbs toward the Bladder, ensuring efficient elimination of damp-heat through the urine.

Notable synergies

Bi Xie and Yi Yi Ren together create a powerful dampness-draining pair: Bi Xie separates the clear from the turbid while Yi Yi Ren strengthens the Spleen's fluid-processing ability, addressing both the symptom and the root of dampness. Huang Bai paired with Mu Dan Pi combines heat-drying with blood-cooling, effectively treating damp-heat that has penetrated to the blood level and manifested as inflamed, red skin lesions. Hua Shi, Ze Xie, and Tong Cao together form a drainage team that opens the urinary pathway at multiple levels to ensure thorough elimination of damp-heat.

How to Prepare

Traditional preparation instructions for Bi Xie Shen Shi Tang

Decoct all eight herbs together in water. As the original text did not specify exact quantities or preparation details, modern practice typically uses approximately 600-800 mL of water, brought to a boil and then simmered on low heat for 20-30 minutes. Strain and divide the resulting liquid into two portions, taken warm in the morning and evening, away from meals.

A standard course of treatment is 5 to 7 days, with one batch of herbs prepared and taken per day. Hua Shi (Talcum) should ideally be wrapped in a cloth pouch (包煎) before decocting to prevent the fine powder from making the decoction gritty.

Common Modifications

How practitioners adapt Bi Xie Shen Shi Tang for specific situations

Added
Bai Xian Pi

10-15g, clears damp-heat and stops itching

Di Fu Zi

10-15g, clears heat from the skin and relieves itching

Bai Xian Pi and Di Fu Zi are a classic pair for damp-heat skin itching. They strengthen the formula's ability to clear damp-heat from the skin surface and relieve the intense pruritus that often accompanies eczema and dermatitis.

Educational content — always consult a qualified healthcare provider or TCM practitioner before using any herbal formula.

Contraindications

Situations where Bi Xie Shen Shi Tang should not be used or requires extra caution

Avoid

Yin Deficiency with Heat signs (dry mouth, night sweats, scanty dark urine without Dampness). This formula is strongly draining and cooling, and will further deplete Yin fluids in someone who lacks them.

Avoid

Spleen-Yang Deficiency with cold signs (cold limbs, loose stools, pale tongue). The cold and draining nature of this formula will further injure Spleen Yang and worsen Dampness from deficiency.

Caution

Prolonged use beyond the resolution of acute symptoms. The formula's strongly clearing and draining herbs (Huang Bai, Hua Shi, Ze Xie) may damage Spleen Qi and Yin if taken long-term.

Caution

Dry-type eczema or skin conditions without weeping, oozing, or signs of Dampness. This formula is designed for the wet, exudative presentation of Damp-Heat and is inappropriate for dry, scaly conditions.

Caution

Patients with significant Qi and Blood Deficiency. The formula contains no tonifying herbs and its draining action may further weaken a constitutionally depleted patient.

Special Populations

Important considerations for pregnancy, breastfeeding, and pediatric use

Pregnancy

Use with caution during pregnancy. Mu Dan Pi (Moutan Cortex) has Blood-moving properties that can theoretically stimulate uterine activity. Ze Xie (Alisma) and Hua Shi (Talcum) are strongly draining diuretics that may deplete fluids. Tong Cao (Tetrapanax pith) also promotes fluid drainage. The overall strongly draining, cooling nature of this formula is generally contraindicated or used only with careful modification during pregnancy. A qualified practitioner should assess the risk-benefit ratio if use is considered necessary.

Breastfeeding

No specific contraindication for breastfeeding has been documented for this formula. However, the strongly cooling and draining nature of the herbs may theoretically reduce milk production by depleting fluids and cooling the system. Huang Bai (Phellodendron) is very bitter and cold, and some of its alkaloid constituents (particularly berberine) may pass into breast milk in small amounts. If breastfeeding, use under practitioner supervision and monitor for any changes in milk supply or infant digestive comfort. Short-term use at standard doses is generally considered lower risk than prolonged courses.

Children

This formula may be used in children with appropriate dose reduction, but generally only for acute Damp-Heat presentations and under practitioner supervision. Children's Spleen systems are considered inherently delicate in TCM, so the strongly draining and cooling herbs in this formula can easily damage digestive function. Typical dose adjustments: children aged 6-12 may use approximately one-half to two-thirds of the adult dose; children under 6 should use one-quarter to one-third. Duration should be kept short (typically no more than 5-7 days in children). One commercial source suggests this type of formula is reserved for children over 12 years of age. Not suitable for infants or toddlers.

Drug Interactions

If you are taking pharmaceutical medications, be aware of these potential interactions with Bi Xie Shen Shi Tang

Diuretic medications: This formula contains multiple herbs with diuretic action (Ze Xie, Hua Shi, Tong Cao, Yi Yi Ren, Chi Fu Ling). Concurrent use with pharmaceutical diuretics (furosemide, hydrochlorothiazide, spironolactone) may produce additive fluid and electrolyte loss, increasing the risk of dehydration and electrolyte imbalances, particularly potassium depletion.

Antihypertensive drugs: The diuretic effects may enhance blood pressure-lowering effects, potentially causing hypotension. Blood pressure should be monitored if combining.

Lithium: Diuretic herbs may alter lithium clearance, potentially increasing lithium levels and toxicity risk. Concurrent use warrants caution and monitoring.

Hypoglycemic agents and insulin: Yi Yi Ren (Coix seed) has been reported to have mild blood sugar-lowering effects. In combination with diabetes medications, blood glucose should be monitored for potential additive hypoglycemic effects.

Anticoagulant and antiplatelet drugs: Mu Dan Pi (Moutan Cortex) has Blood-moving and mild anticoagulant properties. Patients on warfarin, heparin, or antiplatelet agents should be monitored for increased bleeding tendency.

Usage Guidance

Practical advice for getting the most out of Bi Xie Shen Shi Tang

Best time to take

30 minutes to 1 hour before or after meals, twice daily (morning and evening).

Typical duration

Acute use: 5–14 days per course, reassessed by practitioner. Chronic conditions may require 2–4 weeks with periodic reassessment.

Dietary advice

Avoid greasy, fried, and rich foods, which generate Dampness and Heat internally and directly counteract the formula's action. Reduce or eliminate alcohol, spicy foods (chili, black pepper), and heavily sweetened foods, as these all contribute to Damp-Heat accumulation. Dairy products, cold raw foods, and shellfish should also be minimized, as they tend to produce Dampness. Favor light, easily digestible foods such as plain rice congee, mung beans (which also clear Heat), winter melon, barley (Job's tears/Yi Yi Ren can also be eaten as food), cucumber, celery, and lightly steamed vegetables. Adequate plain water intake supports the formula's diuretic action.

Bi Xie Shen Shi Tang originates from Yang Ke Xin De Ji · Bu Yi (疡科心得集·补遗) by Gao Bingjun (高秉钧) Qīng dynasty, 1805 CE

Classical Texts

Key passages from the classical Chinese medical texts that first described Bi Xie Shen Shi Tang and its clinical use

Source text principle (《疡科心得集》general treatment philosophy):

「外科必从内治,熟读《内经》然后可以临证。」
"External conditions must be treated from the inside; one must thoroughly study the Nei Jing before approaching clinical practice."

This foundational principle from Gao Bingju's work explains why Bi Xie Shen Shi Tang, though designed for external skin conditions like leg ulcers and eczema, works entirely through internal medicine logic: clearing Damp-Heat from within and draining it via the urinary tract.

Treatment principle underlying the formula:

「在下部者俱属湿火、湿热,水性下趋故也。」
"Conditions in the lower body all belong to Damp-Fire and Damp-Heat, because water by nature flows downward."

This passage from the Yang Ke Xin De Ji explains the pathological reasoning: Dampness and Heat naturally settle in the lower body, producing the skin lesions, ulcers, and inflammatory conditions this formula targets.

Classical therapeutic principle (治湿经典理论):

「治湿不利小便,非其治也。」
"To treat Dampness without promoting urination is not truly treating it."

This well-known classical principle, referenced by commentators in relation to this formula's mechanism, explains why the formula relies heavily on herbs that promote urination (Ze Xie, Hua Shi, Tong Cao, Chi Fu Ling) to drain Damp-Heat downward and out through the bladder.

Historical Context

How Bi Xie Shen Shi Tang evolved over the centuries — its origins, lineage, and place in the broader tradition of Chinese medicine

Bi Xie Shen Shi Tang originates from the supplementary section (Bu Yi 补遗) of the Yang Ke Xin De Ji (《疡科心得集》, Collected Insights on External Medicine), written by the Qing dynasty physician Gao Bingju (高秉钧, courtesy name Jinting 锦庭, 1755–1827) from Xishan (modern-day Wuxi, Jiangsu province). The book was completed in 1805 (the 10th year of the Jiaqing reign) and first printed in 1806. Gao was a master of both internal and external medicine, renowned throughout the Jiangsu-Zhejiang region. He studied under the physicians Fan Shengxue and Du Yunmen, and devoted himself to deep study of the Huang Di Nei Jing.

Gao Bingju is recognized as the founder of the "Xin De" (Heart's Insight) School of Chinese external medicine, one of the three major schools of TCM surgery/dermatology during the Qing dynasty. His central teaching was that "external conditions must be treated from the inside" (zhi wai bi ben yu nei 治外必本于内). He was a pioneer in integrating Warm Disease (温病 Wen Bing) theory into external medicine, applying concepts like Heat entering the Pericardium to treat serious skin infections. The Yang Ke Xin De Ji contains 104 medical essays and over 260 formulas. Bi Xie Shen Shi Tang exemplifies his approach of treating skin diseases through internal clearing of Damp-Heat rather than relying solely on external applications.

In modern clinical practice, this formula has been widely adapted beyond its original indication for leg ulcers. It is now commonly used for acute eczema, erysipelas of the lower limbs, gout with Damp-Heat pattern, fungal vaginitis, prostatitis, and various other conditions involving Damp-Heat settling in the lower body.