Formula Pill (Wan)

Xiang Sha Yang Wei Wan

Aucklandia and Amomum Stomach-Nourishing Pill · 香砂养胃丸

Also known as: Xiang Sha Yang Wei Wan (香砂养胃丸, Cyperus and Cardamom Stomach-Nourishing Pill)

A widely used traditional formula for digestive discomfort caused by a cold, weak stomach with internal dampness. It warms the digestive system, relieves bloating, stops acid regurgitation, and restores appetite. Particularly suited for people whose stomach pain improves with warmth and who feel tired and heavy after eating.

Origin Za Bing Yuan Liu Xi Zhu (杂病源流犀烛) by Shen Jinao (沈金鳌) — Qīng dynasty, 1773 CE
Composition 12 herbs
Bai Zhu
King
Bai Zhu
Mu Xiang
King
Mu Xiang
Sha Ren
King
Sha Ren
Bai Dou Kou
Deputy
Bai Dou Kou
Huo Xiang
Deputy
Huo Xiang
Chen Pi
Deputy
Chen Pi
Hou Po
Deputy
Hou Po
Xiang Fu
Deputy
Xiang Fu
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Educational content Consult qualified TCM practitioners for diagnosis and treatment

Patterns Addressed

In TCM, symptoms don't appear randomly — they cluster into recognizable patterns of disharmony that reveal what's out of balance in the body. Xiang Sha Yang Wei Wan is designed to correct these specific patterns.

Why Xiang Sha Yang Wei Wan addresses this pattern

When the Stomach's Yang (warming function) is insufficient, it cannot properly 'ripen and rot' food, leading to cold accumulation in the digestive tract. This results in dull stomach pain that improves with warmth and pressure, poor appetite, and a preference for warm drinks. Xiang Sha Yang Wei Wan addresses this through its multiple warming herbs: Sha Ren, Mu Xiang, Dou Kou, and Hou Po all have warm natures that directly restore warmth to the Middle Burner. Bai Zhu tonifies the Spleen Qi that supports Stomach Yang, while Ban Xia descends rebellious Stomach Qi that causes the characteristic acid regurgitation seen when cold disrupts the Stomach's descending function.

A practitioner would look for one or more of these signs

Stomach Pain

Dull, cold stomach pain that improves with warmth or pressure

Acid Reflux

Vomiting of sour or clear watery fluid

Poor Appetite

No desire to eat, especially aversion to cold food

Eye Fatigue

Tiredness and heaviness in the limbs

Post-Surgical Constipation And Bloating

Epigastric fullness and discomfort after eating

Commonly Prescribed For

These conditions can arise from the patterns above. A practitioner would consider Xiang Sha Yang Wei Wan when these conditions are specifically caused by those patterns — not for all cases of these conditions.

Arises from: Stomach Yin Deficiency Cold-Dampness Encumbering the Spleen

TCM Interpretation

In TCM, chronic gastritis is understood as a condition where the Stomach's warming and digestive capacity has been damaged over time, often by irregular eating habits, excessive consumption of cold or raw foods, overwork, or prolonged stress. The Stomach and Spleen become too weak to properly transform food, and dampness accumulates internally. This damp-cold environment further impairs Qi circulation, leading to the characteristic dull pain, fullness, and acid regurgitation. The disease location is in the Stomach, but the Spleen and Liver are closely involved. The Spleen's weakness generates dampness, and Liver Qi stagnation (often from emotional stress) can invade and further disrupt the weakened Stomach.

Why Xiang Sha Yang Wei Wan Helps

Xiang Sha Yang Wei Wan is particularly well suited for chronic gastritis because it simultaneously addresses the root deficiency and the secondary complications. Bai Zhu and Fu Ling rebuild the Spleen's strength, while the cluster of aromatic warming herbs (Sha Ren, Dou Kou, Huo Xiang) restore warmth to the Stomach and transform the accumulated dampness. Mu Xiang and Xiang Fu relieve the pain and distention that characterize gastritis. Ban Xia specifically targets the acid regurgitation and nausea by redirecting rebellious Stomach Qi downward. Modern pharmacological research has shown that this formula can regulate gastrointestinal motility, protect gastric mucosa, and reduce inflammatory markers such as TNF-alpha, IL-6, and IL-8, providing a scientific basis for its traditional use.

Also commonly used for

Peptic Ulcer

Gastric and duodenal ulcers with dull cold pain

Irritable Bowel Syndrome

IBS with predominant bloating, loose stools, and cold intolerance

Nausea

Chronic nausea from Spleen-Stomach weakness

Poor Appetite

Loss of appetite due to digestive weakness

Post-Surgical Constipation And Bloating

Chronic abdominal distention and flatulence

What This Formula Does

Every TCM formula has a specific set of actions — here's what Xiang Sha Yang Wei Wan does in the body, explained in both everyday and TCM terms

Therapeutic focus

In practical terms, Xiang Sha Yang Wei Wan is primarily used to support these areas of health:

TCM Actions

In TCM terminology, these are the specific therapeutic actions that Xiang Sha Yang Wei Wan performs to restore balance in the body:

How It Addresses the Root Cause

TCM doesn't just suppress symptoms — it aims to resolve the underlying imbalance. Here's how Xiang Sha Yang Wei Wan works at the root level.

The core problem this formula addresses is a digestive system weakened by cold and obstructed by dampness. In TCM terms, the Spleen and Stomach together form the central engine of digestion. The Stomach receives food and begins breaking it down ("rotting and ripening"), while the Spleen transforms nutrients and transports them throughout the body. Both organs depend on adequate Yang (warmth) to function properly.

When Stomach Yang becomes insufficient, often from chronic exposure to cold foods, irregular eating habits, overwork, or constitutional weakness, the digestive fire weakens. Food is no longer properly transformed, leading to stagnation and a sensation of fullness or dull pain in the upper abdomen. At the same time, because the Spleen's warming and transforming capacity is impaired, fluids accumulate and congeal into Dampness. This internal Dampness further clogs the Middle Burner, blocking the smooth flow of Qi. The result is a vicious cycle: weak Yang produces Dampness, and Dampness further impedes Yang function. Patients typically experience dull stomach pain relieved by warmth, a heavy or stuffed feeling in the upper abdomen, acid regurgitation, poor appetite, loose stools, and general fatigue in the limbs.

Because Qi movement is obstructed by both cold and dampness, Stomach Qi may rebel upward instead of descending normally, producing nausea, belching, or vomiting of sour fluid. The formula intervenes by simultaneously warming the Middle Burner to restore Yang, drying and resolving the accumulated Dampness, and regulating the flow of Qi to relieve stagnation and pain.

Formula Properties

Every formula has an inherent temperature, taste, and affinity for specific organs — these properties determine how it interacts with the body

Overall Temperature

Warm

Taste Profile

Predominantly acrid (pungent) and bitter with a mild sweet undertone. The acrid taste from the aromatic herbs moves Qi and resolves Dampness, the bitter taste dries Dampness and descends Qi, and the mild sweetness from Bai Zhu, Fu Ling, and Gan Cao gently tonifies the Spleen.

Ingredients

12 herbs

The herbs that make up Xiang Sha Yang Wei Wan, organized by their role in the prescription

King — Main ingredient driving the formula
Deputy — Assists and enhances the King
Assistant — Supports or moderates other herbs
Envoy — Directs the formula to its target
Kings — Main ingredient driving the formula
Bai Zhu

Bai Zhu

White Atractylodes rhizome

Dosage 9 - 12g
Temperature Warm
Taste Bitter (苦 kǔ), Sweet (甘 gān)
Organ Affinity Spleen, Stomach

Role in Xiang Sha Yang Wei Wan

Tonifies the Spleen Qi and dries Dampness. As the core tonifying herb, it addresses the root deficiency of the Spleen and Stomach that underlies the entire pattern. The Spleen prefers dryness and dislikes Dampness, and Bai Zhu fulfills both needs by strengthening digestive function and resolving accumulated moisture.
Mu Xiang

Mu Xiang

Costus root

Dosage 6 - 9g
Temperature Warm
Taste Acrid / Pungent (辛 xīn), Bitter (苦 kǔ)
Organ Affinity Spleen, Stomach, Large Intestine, San Jiao (Triple Burner), Gallbladder

Role in Xiang Sha Yang Wei Wan

Moves Qi in the Middle Burner, harmonizes the Stomach, and stops pain. It addresses the Qi stagnation that causes epigastric fullness and pain, and its warm, acrid nature helps dispel cold from the digestive tract.
Sha Ren

Sha Ren

Amomum fruit

Dosage 6 - 9g
Temperature Warm
Taste Acrid / Pungent (辛 xīn), Aromatic (芳香 fāng xiāng)
Organ Affinity Spleen, Stomach, Kidneys
Preparation Added in the last 5 minutes of decocting (后下)

Role in Xiang Sha Yang Wei Wan

Aromatically awakens the Spleen, warms the Middle Burner, and transforms Dampness. It revives sluggish digestive function and stops vomiting and diarrhea caused by cold-damp accumulation in the Stomach and Spleen.
Deputies — Assists and enhances the King
Bai Dou Kou

Bai Dou Kou

White Cardamom

Dosage 3 - 6g
Temperature Warm
Taste Acrid / Pungent (辛 xīn), Aromatic (芳香 fāng xiāng)
Organ Affinity Lungs, Spleen, Stomach
Preparation Added in the last 5 minutes of decocting (后下); remove outer shell before use

Role in Xiang Sha Yang Wei Wan

Aromatically transforms Dampness, moves Qi, and warms the Middle Burner. It reinforces Sha Ren's ability to awaken the Spleen and stop vomiting, and its aromatic nature helps resolve the turbid dampness blocking the Stomach.
Huo Xiang

Huo Xiang

Patchouli herb

Dosage 6 - 9g
Temperature Slightly Warm
Taste Acrid / Pungent (辛 xīn), Aromatic (芳香 fāng xiāng)
Organ Affinity Spleen, Stomach, Lungs

Role in Xiang Sha Yang Wei Wan

Aromatically transforms Dampness that is obstructing the Spleen and Stomach. It harmonizes the Middle Burner and stops vomiting, supporting the King herbs' strategy of resolving dampness and restoring normal digestive Qi flow.
Chen Pi

Chen Pi

Tangerine peel

Dosage 6 - 9g
Temperature Warm
Taste Acrid / Pungent (辛 xīn), Bitter (苦 kǔ)
Organ Affinity Lungs, Spleen

Role in Xiang Sha Yang Wei Wan

Regulates Qi, harmonizes the Middle Burner, and dries Dampness. It works with Hou Po to relieve distention and fullness while also helping to resolve phlegm-dampness that accumulates when the Spleen is weak.
Hou Po

Hou Po

Magnolia bark

Dosage 6 - 9g
Temperature Warm
Taste Bitter (苦 kǔ), Acrid / Pungent (辛 xīn)
Organ Affinity Spleen, Stomach, Lungs, Large Intestine
Preparation Ginger-processed form (姜厚朴) is used

Role in Xiang Sha Yang Wei Wan

Moves Qi, transforms Dampness, and relieves abdominal fullness and distention. Its warm, bitter, and acrid nature strongly disperses stagnant Qi and dampness in the digestive tract, complementing the Qi-moving action of Mu Xiang.
Xiang Fu

Xiang Fu

Nutgrass Galingale Rhizome

Dosage 6 - 9g
Temperature Neutral
Taste Acrid / Pungent (辛 xīn), Bitter (苦 kǔ), Sweet (甘 gān)
Organ Affinity Liver, Spleen, San Jiao (Triple Burner)
Preparation Vinegar-processed form (醋香附) is used

Role in Xiang Sha Yang Wei Wan

Spreads and regulates Liver Qi, relieves constraint, and stops pain. It addresses the Liver-Stomach disharmony component of the pattern, preventing Liver Qi from invading and further impairing the already weakened Stomach.
Assistants — Supports or moderates other herbs
Fu Ling

Fu Ling

Poria

Dosage 9 - 12g
Temperature Neutral
Taste Sweet (甘 gān), Bland (淡 dàn)
Organ Affinity Heart, Lungs, Spleen, Kidneys

Role in Xiang Sha Yang Wei Wan

Strengthens the Spleen and drains Dampness through the urinary route. It supports Bai Zhu in tonifying the Spleen while providing a downward drainage pathway for the dampness that the aromatic herbs are transforming.
Zhi Shi

Zhi Shi

Immature Bitter Orange Fruit

Dosage 6 - 9g
Temperature Slightly Cool
Taste Bitter (苦 kǔ), Acrid / Pungent (辛 xīn), Sour (酸 suān)
Organ Affinity Spleen, Stomach, Large Intestine
Preparation Dry-fried form (炒枳实) is used

Role in Xiang Sha Yang Wei Wan

Breaks up Qi stagnation, reduces food accumulation, and relieves focal distention. It directs Qi downward more forcefully than the other Qi-moving herbs, helping to clear stubborn food stagnation and epigastric fullness.
Ban Xia

Ban Xia

Pinellia rhizome

Dosage 6 - 9g
Temperature Warm
Taste Acrid / Pungent (辛 xīn)
Organ Affinity Spleen, Stomach, Lungs
Preparation Processed form (制半夏) is used

Role in Xiang Sha Yang Wei Wan

Dries Dampness, transforms Phlegm, and descends rebellious Stomach Qi to stop vomiting and nausea. It supports the overall strategy of resolving dampness while specifically addressing the upward counterflow of Qi that causes acid regurgitation.
Envoy — Directs the formula to its target
Gan Cao

Gan Cao

Licorice root

Dosage 3 - 6g
Temperature Neutral
Taste Sweet (甘 gān)
Organ Affinity Heart, Lungs, Spleen, Stomach

Role in Xiang Sha Yang Wei Wan

Harmonizes all the ingredients in the formula and tonifies the Spleen Qi. Its sweet, neutral nature moderates the drying and Qi-moving properties of the other herbs and supports the Middle Burner.

Why This Combination Works

How the herbs in Xiang Sha Yang Wei Wan complement each other

Overall strategy

This formula addresses a pattern where the Stomach's warming and transforming capacity has declined, allowing cold and dampness to accumulate and obstruct the normal flow of Qi through the digestive system. The prescription strategy combines three approaches: tonifying the underlying Spleen deficiency, aromatically transforming the accumulated dampness, and moving stagnant Qi to relieve pain and distention.

King herbs

Bai Zhu is the primary tonifying King, directly strengthening the Spleen's ability to transform and transport food and fluids. Mu Xiang serves as the primary Qi-moving King, circulating Qi through the Middle Burner to relieve pain and fullness. Sha Ren bridges both strategies as an aromatic King that warms the Spleen and transforms dampness while also moving Qi. Together, these three herbs establish the formula's core action of warming, strengthening, and unblocking the digestive system.

Deputy herbs

Bai Dou Kou and Guang Huo Xiang reinforce Sha Ren's aromatic dampness-transforming action, particularly effective for nausea and vomiting. Chen Pi and Hou Po support Mu Xiang's Qi-regulating action, relieving abdominal distention and drying dampness from a different angle. Xiang Fu adds a unique dimension by soothing the Liver, preventing Liver Qi stagnation from invading and further weakening the Stomach.

Assistant herbs

Fu Ling (reinforcing assistant) supports Bai Zhu in strengthening the Spleen while providing a downward drainage route for dampness through urination. Ban Xia (reinforcing assistant) dries dampness and descends rebellious Stomach Qi, directly targeting nausea, vomiting, and acid regurgitation. Zhi Shi (reinforcing assistant) more forcefully breaks up Qi stagnation and reduces food accumulation, addressing cases where stagnation is more severe.

Envoy herbs

Gan Cao harmonizes the actions of all the other herbs and gently tonifies the Middle Burner. Its sweet nature also moderates the strong drying and Qi-moving properties of the formula, preventing them from being overly harsh on an already weakened digestive system.

Notable synergies

Bai Zhu paired with Fu Ling forms the classic Spleen-tonifying and dampness-draining combination, simultaneously strengthening digestion and removing pathological moisture. Mu Xiang paired with Sha Ren is a renowned combination for moving Qi and warming the Stomach, used across many digestive formulas. Chen Pi paired with Ban Xia echoes the Er Chen Tang (Two-Cured Decoction) structure for transforming phlegm-dampness. The overall formula builds upon the Xiang Sha Liu Jun Zi Tang framework but substitutes Ren Shen with additional aromatic Qi-moving herbs, making it more focused on resolving dampness and stagnation than on pure Qi tonification.

How to Prepare

Traditional preparation instructions for Xiang Sha Yang Wei Wan

As a prepared patent medicine (中成药), Xiang Sha Yang Wei Wan is manufactured as small black water pills (水丸). The standard dosage is 9 grams taken orally, twice daily, swallowed with warm water. Using warm ginger water to take the pills can enhance the formula's anti-nausea effect.

If prepared as a decoction from raw herbs, combine the herbs in the proportions listed and decoct in water. Sha Ren (Amomum) and Dou Kou (Cardamom) should be added during the last 5 minutes of decocting (后下) to preserve their volatile aromatic oils. Decoct the remaining herbs for approximately 20-30 minutes, then strain and drink warm.

Common Modifications

How practitioners adapt Xiang Sha Yang Wei Wan for specific situations

Added
Gan Jiang

6-9g, strongly warms the Middle Burner and dispels internal cold

Gao Liang jiang

6-9g, warms the Stomach and stops pain

When cold is the dominant pathogenic factor causing severe stomach pain that dramatically improves with applied warmth, adding stronger warming herbs intensifies the formula's cold-dispelling action.

Educational content — always consult a qualified healthcare provider or TCM practitioner before using any herbal formula.

Contraindications

Situations where Xiang Sha Yang Wei Wan should not be used or requires extra caution

Avoid

Pregnancy. The formula contains Ban Xia (Pinellia), which is traditionally contraindicated in pregnancy, and Zhi Shi (Immature Bitter Orange), which has Qi-descending and breaking properties. Multiple Chinese pharmacopoeia product labels list pregnancy as a prohibited use.

Avoid

Stomach Yin Deficiency patterns, presenting as dry mouth with desire to drink, dry stools, and reduced urination. The formula is warm and drying in nature, which would further damage Yin fluids.

Avoid

Stomach Fire or Heat patterns with symptoms such as burning epigastric pain, bad breath, excessive hunger, or a red tongue with yellow coating. The warming, aromatic herbs would aggravate internal Heat.

Caution

Diabetes. Some commercial preparations list diabetes as a contraindication due to the sugar excipients used and the warming nature of the formula.

Avoid

Known allergy to any component of the formula. Allergic reactions including skin rash and itching have been reported in sensitive individuals.

Caution

Long-term unsupervised use. The formula's warm and aromatic-drying nature may, over extended periods, lead to dryness symptoms such as dry mouth, constipation, and dark urine.

Caution

Patients with severe hypertension, heart disease, liver disease, or kidney disease should use only under close medical supervision due to the Gan Cao (Licorice) content and the complexity of the multi-herb formulation.

Special Populations

Important considerations for pregnancy, breastfeeding, and pediatric use

Pregnancy

Contraindicated during pregnancy. The formula contains Ban Xia (Pinellia, processed), which is classically listed as a pregnancy-contraindicated herb. It also contains Zhi Shi (Immature Bitter Orange), which has strong Qi-descending and stagnation-breaking properties that could theoretically affect the uterus. Additionally, Xiang Fu (Cyperus) is a potent Qi-regulating herb that affects the Liver channel and menstrual regulation. Multiple Chinese pharmaceutical product labels explicitly prohibit use by pregnant women (孕妇禁用). Women who are pregnant or planning to become pregnant should not take this formula.

Breastfeeding

Use with caution during breastfeeding. While the formula's herbs are generally considered to have relatively low toxicity and are widely used in clinical practice, several aromatic and warm-drying herbs (Ban Xia, Hou Po, Mu Xiang) may transfer constituents through breast milk. There is no established safety data specific to breastfeeding. The official product labeling advises that breastfeeding women should use this formula only under medical guidance. If breastfeeding mothers experience signs of excessive dryness or the infant shows digestive disturbance, the formula should be discontinued.

Children

Children may use this formula but only under the supervision of a qualified practitioner. The official product labeling states that children must use it under adult supervision and that pediatric or elderly patients should be guided by a physician. Dosage should be reduced proportionally based on the child's age and weight, typically to one-third to one-half of the adult dose for school-age children. This formula is generally not recommended for very young children (under 3 years) without specific medical guidance, as its warm and aromatic-drying nature may be too strong for immature digestive systems.

Drug Interactions

If you are taking pharmaceutical medications, be aware of these potential interactions with Xiang Sha Yang Wei Wan

Gan Cao (Licorice Root): This formula contains Gan Cao, which contains glycyrrhizin. Licorice can cause pseudoaldosteronism (sodium retention, potassium loss, elevated blood pressure) with prolonged use. It may interact with antihypertensive medications, reducing their effectiveness. It can potentiate the effects of cardiac glycosides (e.g. digoxin) by promoting hypokalemia. It may enhance potassium depletion caused by thiazide diuretics and stimulant laxatives. It may also interact with corticosteroids by augmenting their mineralocorticoid effects.

Ban Xia (Processed Pinellia): Ban Xia is classically listed as incompatible with Wu Tou (Aconite root) according to the "Eighteen Incompatibles" (十八反) principle in TCM. If a patient is concurrently taking any Aconite-containing preparation (Fu Zi Li Zhong Wan, etc.), this combination should be avoided.

General caution: The formula's multiple aromatic and Qi-moving herbs may theoretically alter gastrointestinal motility and absorption rates, potentially affecting the bioavailability of concurrently administered oral medications. Patients taking prescription drugs for chronic conditions such as hypertension, heart disease, liver disease, diabetes, or kidney disease should consult their physician before concurrent use.

Usage Guidance

Practical advice for getting the most out of Xiang Sha Yang Wei Wan

Best time to take

30 minutes before meals, taken with warm water, twice daily.

Typical duration

Short to medium-term use: typically 1-4 weeks for acute symptoms, reassessed after 3 days if no improvement. Not recommended for long-term continuous use without practitioner supervision due to its warm and drying nature.

Dietary advice

Avoid cold and raw foods (salads, ice cream, cold beverages, sushi) as these directly oppose the warming action of the formula and worsen cold-dampness in the Stomach. Avoid greasy, fried, and heavy foods, which burden the already weakened Spleen and generate more Dampness. Avoid spicy, strongly pungent foods, alcohol, coffee, and strong tea, which can irritate the stomach lining. Favor warm, easily digestible foods such as congee (rice porridge), well-cooked soups, steamed vegetables, and modest portions of warm ginger tea. Eat regular meals at consistent times and avoid overeating or skipping meals. Taking the formula with warm water or ginger decoction may enhance its anti-nausea effect.

Xiang Sha Yang Wei Wan originates from Za Bing Yuan Liu Xi Zhu (杂病源流犀烛) by Shen Jinao (沈金鳌) Qīng dynasty, 1773 CE

Classical Texts

Key passages from the classical Chinese medical texts that first described Xiang Sha Yang Wei Wan and its clinical use

There are no widely cited classical quotes directly attributed to the Xiang Sha Yang Wei Wan formula entry itself. The formula originates from Shen Jinao's (沈金鳌) Qing dynasty work Za Bing Yuan Liu Xi Zhu (《杂病源流犀烛》, "Incisive Light on the Source and Course of Miscellaneous Diseases"), completed in 1773. The official pharmacopoeia indication reads:

「温中和胃。用于胃阳不足、湿阻气滞所致的胃痛、痞满,症见胃痛隐隐、脘闷不舒、呕吐酸水、嘈杂不适、不思饮食、四肢倦怠。」

"Warms the Middle Burner and harmonizes the Stomach. Used for stomach pain and focal distention caused by insufficiency of Stomach Yang with Dampness obstructing Qi movement, presenting as dull stomach pain, epigastric stuffiness, acid regurgitation, gnawing discomfort, loss of appetite, and fatigue of the four limbs."

This text is recorded in the Pharmacopoeia of the People's Republic of China (《中华人民共和国药典》) as the official functional indication for the formula.

Historical Context

How Xiang Sha Yang Wei Wan evolved over the centuries — its origins, lineage, and place in the broader tradition of Chinese medicine

Xiang Sha Yang Wei Wan is attributed to the Qing dynasty physician Shen Jinao (沈金鳌, 1717-1776), who recorded it in his major clinical work Za Bing Yuan Liu Xi Zhu (《杂病源流犀烛》, "Incisive Light on the Source and Course of Miscellaneous Diseases"), completed around 1773. Shen Jinao was a scholar-physician from Wuxi in Jiangsu province. His complete medical writings were collected under the title Shen Shi Zun Sheng Shu (《沈氏尊生书》, "Mr. Shen's Book for Honoring Life"), which encompasses works on miscellaneous diseases, gynecology, pediatrics, materia medica classification, and Shang Han Lun commentary.

The formula's design draws upon the earlier Xiang Sha Liu Jun Zi Tang ("Aucklandia and Amomum Six Gentlemen Decoction"), a well-known Qi-tonifying and Dampness-resolving formula. Shen Jinao's modification removed Ren Shen (Ginseng) and added herbs such as Xiang Fu, Zhi Shi, Bai Dou Kou, Huo Xiang, and Hou Po, shifting the emphasis from pure Qi tonification toward stronger aromatic transformation of Dampness, Qi regulation, and pain relief. This made the formula more practically suited for the common clinical presentation of cold-dampness stomach complaints.

In modern China, Xiang Sha Yang Wei Wan has become one of the most widely used over-the-counter patent medicines for digestive complaints. It is included in the Pharmacopoeia of the People's Republic of China (中国药典) and is classified as a non-prescription warming and dampness-resolving agent covered by medical insurance. It remains a household staple for managing chronic gastritis, functional dyspepsia, and acid reflux symptoms associated with cold-dampness patterns.

Modern Research

A published study investigating the pharmacological effects or clinical outcomes of Xiang Sha Yang Wei Wan

1

RCT: Xiangsha Yangwei Pills combined with Teprenone Capsules in treatment of chronic atrophic gastritis (2017)

Yang Y, Wang BX, Ren QH, Fu AG, Ding HR. Clinical study on Xiangsha Yangwei Pills combined with Teprenone Capsules in treatment of chronic atrophic gastritis. Modern Drugs & Clinical (现代药物与临床). 2017;32(1):93-97.

This randomized controlled trial enrolled 110 patients with chronic atrophic gastritis, randomly assigned to Teprenone alone or Teprenone plus Xiang Sha Yang Wei Wan for 8 weeks. The combination group showed a significantly higher total effective rate (92.7% vs. 74.5%), with greater improvements in gastric mucosal scores, quality of life measures, and reductions in inflammatory markers (TNF-alpha, IL-6, IL-8) compared to the control group.

Research on TCM formulas is growing but still limited by Western clinical trial standards. These studies provide emerging evidence and should be considered alongside practitioner expertise.