E Jiao Ji Zi Huang Tang

Ass-Hide Gelatin and Egg Yolk Decoction · 阿膠雞子黃湯

Also known as: Donkey-Hide Gelatin and Egg Yolk Decoction

A classical formula for calming internal tremors, spasms, and dizziness caused by a deep depletion of the body's nourishing fluids and Blood. It works by replenishing Yin and Blood to soothe the Liver and quiet involuntary muscle movements, and is often used after prolonged febrile illness that has dried out the body's resources.

Origin Tōng Sú Shāng Hán Lùn (通俗傷寒論, Revised Popular Guide to Cold Damage Disorders) by Yú Gēnchū (俞根初) — Qīng dynasty, 1776 CE
Composition 10 herbs
E Jiao
King
E Jiao
Ji Zi Huang
King
Ji Zi Huang
Shu Di Huang
Deputy
Shu Di Huang
Bai Shao
Deputy
Bai Shao
Shi Jue Ming
Assistant
Shi Jue Ming
Gou Teng
Assistant
Gou Teng
Mu Li
Assistant
Mu Li
Luo Shi Teng
Assistant
Luo Shi Teng
+2
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Explore composition

Educational content Consult qualified TCM practitioners for diagnosis and treatment

Patterns Addressed

In TCM, symptoms don't appear randomly — they cluster into recognizable patterns of disharmony that reveal what's out of balance in the body. E Jiao Ji Zi Huang Tang is designed to correct these specific patterns.

Why E Jiao Ji Zi Huang Tang addresses this pattern

When Yin and Blood become severely depleted, the Liver loses its nourishment. In TCM, the Liver governs the sinews and stores Blood. When Liver Blood is insufficient, the sinews are malnourished, and 'Wind' stirs internally, producing involuntary movements like tremors, twitching, and spasms. This formula addresses this pattern by using E Jiao and Ji Zi Huang to deeply replenish Yin and Blood, Sheng Di Huang and Bai Shao to nourish and soften the Liver, and Gou Teng, Shi Jue Ming, and Mu Li to directly calm the stirring Wind and anchor the floating Yang. The result is that the Liver is re-nourished, the sinews are relaxed, and the internal Wind settles.

A practitioner would look for one or more of these signs

Muscle Spasm

Twitching and spasms of the hands and feet (瘛疭)

Tremors

Involuntary trembling of the limbs

Dizziness

Dizziness and vertigo

Dry Mouth

Dry mouth and parched lips

Insomnia

Restlessness and difficulty sleeping

Commonly Prescribed For

These conditions can arise from the patterns above. A practitioner would consider E Jiao Ji Zi Huang Tang when these conditions are specifically caused by those patterns — not for all cases of these conditions.

TCM Interpretation

In TCM, tremor is understood as a manifestation of internal Wind, most often arising from the Liver system. The Liver governs the sinews (muscles and tendons), and when Liver Blood and Yin are depleted, the sinews lose their nourishment and begin to move involuntarily. This is distinct from external Wind (like catching a cold) and is called 'deficiency Wind' because it arises from internal emptiness rather than excess. The trembling worsens with fatigue and stress, both of which further deplete the already-deficient Yin and Blood.

Why E Jiao Ji Zi Huang Tang Helps

E Jiao Ji Zi Huang Tang addresses tremor by rebuilding the Yin and Blood foundation that the Liver needs to properly govern the sinews. E Jiao and Ji Zi Huang provide deep, substantive nourishment as animal-derived products with special affinity for replenishing depleted Yin. Sheng Di Huang and Bai Shao further enrich Liver Blood and soften Liver tension. Meanwhile, Gou Teng directly calms Liver Wind and relieves spasms, while the heavy shells (Shi Jue Ming, Mu Li) anchor the floating Yang that drives the involuntary movements. Luo Shi Teng guides the formula's effects into the channels and sinews where the tremor manifests.

Also commonly used for

Muscle Spasm

Post-febrile muscle spasms and involuntary movements

Encephalitis

Late-stage sequelae of viral encephalitis (e.g. Japanese encephalitis)

Meningitis

Post-meningitis neurological symptoms

Hypertension

Hypertension with dizziness from Yin deficiency pattern

Insomnia

Insomnia with restlessness from Yin-Blood deficiency

What This Formula Does

Every TCM formula has a specific set of actions — here's what E Jiao Ji Zi Huang Tang does in the body, explained in both everyday and TCM terms

Therapeutic focus

In practical terms, E Jiao Ji Zi Huang Tang is primarily used to support these areas of health:

TCM Actions

In TCM terminology, these are the specific therapeutic actions that E Jiao Ji Zi Huang Tang performs to restore balance in the body:

How It Addresses the Root Cause

TCM doesn't just suppress symptoms — it aims to resolve the underlying imbalance. Here's how E Jiao Ji Zi Huang Tang works at the root level.

This formula addresses a pattern where prolonged pathogenic Heat (often from a febrile disease) has gradually consumed the body's Yin and Blood. In TCM theory, the Liver depends on adequate Blood and Yin to remain soft and supple. When Yin and Blood become severely depleted, the Liver loses its nourishment: Liver Yang, no longer held in check by sufficient Yin, rises unchecked and transforms into internal Wind.

This internal Wind is fundamentally different from external Wind (like catching a cold). It is generated from within, driven by emptiness rather than by an invading pathogen. The depleted Yin cannot anchor the Yang, so it floats upward and outward, producing symptoms such as tremors, muscle twitching, and spasms in the limbs, as well as dizziness and vertigo. The tongue appears deep red because the Yin fluids that normally moisten it are exhausted, and the thin, rapid pulse reflects both the Blood deficiency (thin) and the residual Heat consuming Yin (rapid).

The disease logic can be summarized as a vicious cycle: Heat damages Yin, Yin deficiency fails to restrain Liver Yang, unrestrained Yang generates Wind, and Wind movement further scatters the remaining Yin. Breaking this cycle requires simultaneously nourishing the depleted Yin and Blood to rebuild the foundation, calming the rising Liver Yang, and extinguishing the internal Wind. This is the therapeutic strategy the formula embodies.

Formula Properties

Every formula has an inherent temperature, taste, and affinity for specific organs — these properties determine how it interacts with the body

Overall Temperature

Slightly Cool

Taste Profile

Predominantly sweet and salty with mild bitterness and sourness. Sweet to nourish Yin and Blood, salty to soften hardness and anchor rising Yang, sour to astringe and preserve Yin, bitter to gently cool residual Heat.

Channels Entered

Ingredients

10 herbs

The herbs that make up E Jiao Ji Zi Huang Tang, organized by their role in the prescription

King — Main ingredient driving the formula
Deputy — Assists and enhances the King
Assistant — Supports or moderates other herbs
Envoy — Directs the formula to its target
Kings — Main ingredient driving the formula
E Jiao

E Jiao

Donkey-hide gelatin

Dosage 6g
Temperature Neutral
Taste Sweet (甘 gān)
Organ Affinity Lungs, Liver, Kidneys
Preparation Dissolve separately (烊冲, yáng chōng) into the strained decoction

Role in E Jiao Ji Zi Huang Tang

As a Blood-and-Yin nourishing substance (a 'blood-flesh sentient product'), E Jiao directly replenishes the depleted Yin and Blood that underlie the internal Wind. By enriching Liver and Kidney Yin, it addresses the root cause of the formula's target pattern.
Ji Zi Huang

Ji Zi Huang

Egg yolk

Dosage 2 yolks
Temperature Neutral
Taste Sweet (甘 gān)
Organ Affinity Heart, Kidneys, Spleen
Preparation Blend raw into the warm (not hot) strained decoction (先煎代水)

Role in E Jiao Ji Zi Huang Tang

Another blood-flesh sentient product that powerfully nourishes Yin and Blood. Ji Zi Huang enriches the Liver and Kidney, calms the spirit, and works in tandem with E Jiao to extinguish Wind through deep Yin nourishment. It also harmonizes the formula and moderates the mineral heaviness of other ingredients.
Deputies — Assists and enhances the King
Shu Di Huang

Shu Di Huang

Prepared Rehmannia root

Dosage 12g
Temperature Slightly Warm
Taste Sweet (甘 gān)
Organ Affinity Liver, Kidneys

Role in E Jiao Ji Zi Huang Tang

Cool in nature, Sheng Di Huang nourishes Yin and cools the Blood. It reinforces the King herbs' Yin-replenishing action and clears residual Heat from the Blood level, which is important in post-febrile Yin depletion.
Bai Shao

Bai Shao

White peony root

Dosage 9g
Temperature Slightly Cool
Taste Bitter (苦 kǔ), Sour (酸 suān)
Organ Affinity Liver, Spleen

Role in E Jiao Ji Zi Huang Tang

Nourishes Liver Blood and softens the Liver to relieve spasms. Its sour and astringent quality helps preserve Yin fluids and relaxes tense sinews, directly addressing the spasms and twitching of the Wind pattern.
Assistants — Supports or moderates other herbs
Shi Jue Ming

Shi Jue Ming

Abalone shell

Dosage 15g
Temperature Cold
Taste Salty (咸 xián)
Organ Affinity Liver
Preparation Pre-crush and decoct first for 20–30 minutes (先煎)

Role in E Jiao Ji Zi Huang Tang

A heavy mineral/shell substance that anchors rising Liver Yang and calms Liver Wind. It clears Liver Heat and subdues the upward-stirring Yang that contributes to dizziness and vertigo.
Gou Teng

Gou Teng

Uncaria hook vine

Dosage 6g
Temperature Cool
Taste Sweet (甘 gān)
Organ Affinity Liver, Pericardium
Preparation Add in the last 5 minutes of decocting (后下)

Role in E Jiao Ji Zi Huang Tang

Clears Liver Heat and extinguishes Wind, directly calming spasms and tremors. Its cool nature helps settle hyperactive Liver Yang without being overly cold.
Mu Li

Mu Li

Oyster shell

Dosage 12g
Temperature Slightly Cool
Taste Salty (咸 xián), Astringent (涩 sè)
Organ Affinity Liver, Gallbladder, Kidneys
Preparation Pre-crush and decoct first for 20–30 minutes (先煎)

Role in E Jiao Ji Zi Huang Tang

Heavy and salty, Mu Li subdues floating Yang, anchors the spirit, and nourishes Yin. Together with Shi Jue Ming, it forms a strong mineral anchor to suppress the upward and outward movement of deficiency Wind.
Luo Shi Teng

Luo Shi Teng

Star jasmine vine

Dosage 9g
Temperature Slightly Cool
Taste Bitter (苦 kǔ)
Organ Affinity Heart, Liver, Kidneys

Role in E Jiao Ji Zi Huang Tang

Clears Heat from the channels and collaterals, soothes the sinews, and unblocks the network vessels. It directs the formula's action to the limbs and sinews where the spasms and rigidity manifest.
Fu Shen

Fu Shen

Spirit Poria

Dosage 12g
Temperature Neutral
Taste Sweet (甘 gān), Bland (淡 dàn)
Organ Affinity Heart, Spleen

Role in E Jiao Ji Zi Huang Tang

Calms the spirit and settles the mind. In this formula, it addresses the restlessness and anxiety that often accompany Yin deficiency and internal Wind, while gently supporting the Spleen to prevent the rich Yin-nourishing herbs from burdening digestion.
Envoy — Directs the formula to its target
Gan Cao

Gan Cao

Licorice root

Dosage 2g
Temperature Neutral
Taste Sweet (甘 gān)
Organ Affinity Heart, Lungs, Spleen, Stomach

Role in E Jiao Ji Zi Huang Tang

Harmonizes all the other herbs in the formula. Combined with Bai Shao, it forms the classic pairing (Shao Yao Gan Cao Tang) that relaxes spasms and relieves cramping in the sinews, adding an additional anti-spasmodic action.

Why This Combination Works

How the herbs in E Jiao Ji Zi Huang Tang complement each other

Overall strategy

This formula treats internal Wind arising from severe Yin and Blood deficiency, typically after prolonged febrile illness has consumed the body's nourishing fluids. The strategy is to extinguish Wind by addressing its root: replenishing the depleted Yin and Blood that can no longer anchor and nourish the Liver, while simultaneously using heavy mineral substances to suppress the upward stirring of deficiency Wind.

King herbs

E Jiao and Ji Zi Huang are both 'blood-flesh sentient products' (血肉有情之品), meaning they are animal-derived substances with a special affinity for replenishing the body's deepest Yin and Blood reserves. E Jiao nourishes Liver and Kidney Yin and enriches the Blood. Ji Zi Huang supplements Yin from below (Kidney) and settles the spirit above (Heart), providing a rich, substantive form of nourishment that plant-based herbs alone cannot match. Together, they address the core deficiency that allows Wind to stir internally.

Deputy herbs

Sheng Di Huang reinforces the Yin-nourishing action of the King herbs while also cooling residual Heat in the Blood, which is critical given that this pattern typically follows prolonged Heat illness. Bai Shao nourishes Liver Blood directly and softens the Liver through its sour, astringent nature, helping to relax the tense sinews and ease the spasms that characterize this pattern.

Assistant herbs

Shi Jue Ming and Mu Li are heavy shell substances that anchor floating Yang and subdue Liver Wind from above (restraining assistants). Where the King and Deputy herbs work from below by replenishing the Yin foundation, these minerals work from above by weighing down the hyperactive Yang. Gou Teng clears Liver Heat and directly extinguishes Wind, providing a more immediate anti-spasmodic effect (reinforcing assistant). Luo Shi Teng directs the formula's action into the channels and collaterals where Wind causes the physical symptoms of spasm and rigidity (reinforcing assistant). Fu Shen calms the spirit and prevents the restlessness that accompanies Yin-deficient Wind (reinforcing assistant).

Envoy herbs

Zhi Gan Cao harmonizes the entire formula and moderates the heavy mineral substances. Paired with Bai Shao, it creates the classical Shao Yao Gan Cao Tang combination, which relaxes sinew tension and relieves cramping, adding a gentle anti-spasmodic layer to the formula's overall effect.

Notable synergies

E Jiao paired with Ji Zi Huang creates a powerfully rich Yin-nourishing combination that no single herb could achieve alone, as both are animal-derived substances that target the deepest level of Yin replenishment. Shi Jue Ming paired with Mu Li provides a dual mineral anchor that suppresses floating Yang from multiple angles. Bai Shao paired with Zhi Gan Cao (the Shao Yao Gan Cao Tang combination) is a time-tested pairing for relaxing muscle spasms, perfectly complementing the Wind-extinguishing strategy of the other ingredients.

How to Prepare

Traditional preparation instructions for E Jiao Ji Zi Huang Tang

Decoct Shi Jue Ming (pre-crushed) and Mu Li (pre-crushed) first for 20–30 minutes in approximately 800–1000 mL of water. Then add Sheng Di Huang, Bai Shao, Gou Teng, Luo Shi Teng, Fu Shen, and Zhi Gan Cao. Boil together until approximately 300 mL of liquid remains. Remove from heat, strain out the dregs, and dissolve E Jiao (pre-melted separately or added directly to the hot strained liquid) by stirring until fully incorporated.

Allow the decoction to cool slightly until warm (not hot), then blend in two raw egg yolks (Ji Zi Huang), stirring thoroughly until evenly mixed. Divide into two portions and take warm, once in the morning and once in the evening. Note: Gou Teng should ideally be added in the last 5 minutes of decocting to preserve its active properties.

Common Modifications

How practitioners adapt E Jiao Ji Zi Huang Tang for specific situations

Added
Tian Ma

9–12g, to calm Liver Wind and stop dizziness

Ju Hua

9g, to clear Liver Heat and brighten the eyes

Tian Ma is a premier herb for Liver Wind dizziness and synergizes with Gou Teng to form the classic Tian Ma Gou Teng pairing for calming ascending Liver Yang.

Educational content — always consult a qualified healthcare provider or TCM practitioner before using any herbal formula.

Contraindications

Situations where E Jiao Ji Zi Huang Tang should not be used or requires extra caution

Avoid

Excess or replete Wind patterns (e.g. acute Wind-Cold or Wind-Heat invasion with strong exterior signs). This formula treats internal Wind from deficiency, not external Wind.

Avoid

Spleen-Yang deficiency with Dampness or Phlegm accumulation. The heavily nourishing, cloying nature of E Jiao, Sheng Di Huang, and Ji Zi Huang can further obstruct the middle burner and worsen Dampness.

Caution

Excess Heat or Fire patterns without underlying Yin or Blood deficiency. This formula is designed for deficiency-type internal Wind, not for robust excess Heat stirring Wind.

Caution

Loose stools or poor appetite due to Spleen Qi deficiency. The rich, moist herbs in the formula may impair digestion further. If used, add herbs that support the Spleen such as Fu Ling or Chen Pi.

Caution

Patients currently on anticoagulant or antiplatelet medications should exercise caution, as E Jiao (donkey-hide gelatin) may have mild effects on coagulation.

Special Populations

Important considerations for pregnancy, breastfeeding, and pediatric use

Pregnancy

Generally considered relatively safe compared to formulas containing strongly moving or hot herbs, but should still be used with caution during pregnancy and only under professional guidance. Gou Teng (Uncaria) and Mu Li (Oyster shell) are generally regarded as safe, and E Jiao is traditionally used to calm the fetus. However, Sheng Di Huang (raw Rehmannia) is cold in nature and can be difficult on the digestion of pregnant women, and the overall strongly Yin-nourishing, cloying character of the formula may cause digestive issues. The formula was designed for a specific pathological state (internal Wind from Yin/Blood deficiency after febrile illness), not as a tonic for pregnancy. Use only if the pattern clearly fits and under the supervision of a qualified practitioner.

Breastfeeding

No specific contraindication during breastfeeding has been established for this formula. The primary ingredients (E Jiao, Sheng Di Huang, Bai Shao, Gou Teng, Shi Jue Ming, Mu Li, Fu Shen, Luo Shi Teng, Zhi Gan Cao, Ji Zi Huang) are not known to produce toxic metabolites that transfer through breast milk. However, the formula's strongly nourishing, cloying nature could theoretically affect the mother's digestion and thereby milk quality. If the breastfeeding mother clearly presents with the target pattern (Yin/Blood deficiency with internal Wind), the formula may be used under professional supervision. Monitor the infant for any changes in feeding behavior or stool consistency.

Children

This formula can be adapted for pediatric use, particularly in cases of post-febrile convulsions or tremors in children due to Yin/Blood depletion. Dosage should be reduced to approximately one-third to one-half of the adult dose for children aged 6-12, and one-quarter for children under 6, adjusted by body weight and the child's constitution. The egg yolk (Ji Zi Huang) component should be confirmed safe (no egg allergy). Children's Spleen and Stomach functions are inherently immature, so the rich, cloying herbs (E Jiao, Sheng Di Huang) should be used cautiously; consider reducing their proportion or adding Spleen-supporting herbs. The mineral/shell ingredients (Shi Jue Ming, Mu Li) should be decocted first (pre-boiled for 20-30 minutes) to extract properly and reduce any potential digestive burden. Not suitable for infants under 1 year without specialist guidance.

Drug Interactions

If you are taking pharmaceutical medications, be aware of these potential interactions with E Jiao Ji Zi Huang Tang

Anticoagulant and antiplatelet drugs (e.g. warfarin, aspirin, clopidogrel): E Jiao (donkey-hide gelatin) may have mild effects on coagulation. While there is no definitive clinical evidence of a significant interaction, concurrent use may theoretically alter INR values or increase bleeding risk. Patients on these medications should have their coagulation markers monitored if this formula is prescribed.

Antihypertensive medications: Gou Teng (Uncaria) and Shi Jue Ming (Haliotis shell) have demonstrated mild blood-pressure-lowering effects in pharmacological studies. Combined use with antihypertensives could theoretically result in additive hypotensive effects. Blood pressure monitoring is advisable.

Gan Cao (Glycyrrhiza, licorice): Though present in small amounts (2g), Gan Cao may interact with corticosteroids, digoxin, loop diuretics, and thiazide diuretics. It can promote potassium loss and sodium/water retention. At this low dose the risk is small, but should be noted for patients on these medications, especially with prolonged use.

General advice: Separate the administration of this formula from any Western pharmaceutical medication by at least 1-2 hours to minimize direct interactions in the digestive tract.

Usage Guidance

Practical advice for getting the most out of E Jiao Ji Zi Huang Tang

Best time to take

Twice daily, 30-60 minutes after meals (to reduce the cloying effect on the stomach). Egg yolks should be blended into the warm (not hot) strained decoction just before drinking.

Typical duration

Acute use for post-febrile tremors or convulsions: 7-14 days. Chronic conditions (e.g. dizziness from Yin deficiency, Parkinson's-like tremor): 4-8 weeks with periodic reassessment.

Dietary advice

Favor foods that nourish Yin and Blood: black sesame, goji berries, mulberries, walnuts, dark leafy greens, eggs, and bone broth. Light, easy-to-digest meals are preferred to avoid taxing the Spleen. Avoid foods and substances that generate internal Heat or aggravate Liver Yang: alcohol, coffee, strong spices (chili, black pepper, cinnamon), deep-fried foods, and rich fatty meats. Avoid raw and cold foods that could impair the Spleen's ability to absorb the formula's nourishing ingredients. Reduce stress and avoid emotional agitation during treatment, as anger and frustration directly affect the Liver and can counteract the formula's calming effect on Liver Yang.

E Jiao Ji Zi Huang Tang originates from Tōng Sú Shāng Hán Lùn (通俗傷寒論, Revised Popular Guide to Cold Damage Disorders) by Yú Gēnchū (俞根初) Qīng dynasty, 1776 CE

Classical Texts

Key passages from the classical Chinese medical texts that first described E Jiao Ji Zi Huang Tang and its clinical use

Source text (Tong Su Shang Han Lun, 通俗伤寒论, by Yu Genchu):

The formula is indicated for: 「邪热久羁,损伤阴血。虚风内动,手足瘛疭,或头目眩晕,舌绛苔少,脉细数。」

"Pathogenic Heat lingering for a long time, damaging Yin and Blood. Deficiency-type internal Wind stirring, with spasms and twitching of the hands and feet, or dizziness and vertigo, a deep-red tongue with scant coating, and a thin, rapid pulse."

Formula mnemonic (方歌):

「阿胶鸡子黄汤好,地芍钩藤牡栃草,决明茯神络石藤,阴虚动风此方保。」

"E Jiao Ji Zi Huang Tang is fine; Di [Huang], Shao [Yao], Gou Teng, Mu [Li], Zhi [Gan] Cao; [Shi] Jue Ming, Fu Shen, Luo Shi Teng; for Yin-deficiency stirring Wind, this formula protects."

Historical Context

How E Jiao Ji Zi Huang Tang evolved over the centuries — its origins, lineage, and place in the broader tradition of Chinese medicine

E Jiao Ji Zi Huang Tang originates from the Tong Su Shang Han Lun (通俗伤寒论, "Revised Popular Guide to the Discussion of Cold-Induced Disorders"), written by the Qing dynasty physician Yu Genchu (俞根初). Yu Genchu was a key figure of the "Shaoxing school of Shang Han" (绍派伤寒), a regional medical tradition from the Shaoxing area of Zhejiang province that was known for integrating classical Shang Han Lun methods with the Warm Disease (Wen Bing) approach. His original manuscript was later edited by He Xiushan, further revised by He Lianchen (He Xiushan's grandson), and finally supplemented by Cao Bingzhang, expanding the work into twelve volumes.

The formula represents a sophisticated development in the treatment of internal Wind. While earlier formulas like Zhang Zhongjing's Huang Lian E Jiao Tang (from the Shang Han Lun) used E Jiao and Ji Zi Huang to nourish Yin and clear Heart Fire for insomnia patterns, Yu Genchu redirected these same nourishing substances toward the Liver system, combining them with Wind-calming and Yang-subduing medicinals like Gou Teng, Shi Jue Ming, and Mu Li. This reflects the Qing dynasty's maturation of Liver Wind theory, where clinicians increasingly recognized that late-stage febrile diseases could damage Yin enough to trigger internal Wind, a dangerous development requiring both nourishment and Wind suppression simultaneously.

In modern clinical practice, the formula has been applied beyond its original febrile disease context to conditions such as cerebral arteriosclerosis with dizziness, facial muscle spasm, Parkinson's-like tremor, and post-encephalitis sequelae, all sharing the underlying pattern of Yin/Blood deficiency generating internal Wind.