Xiao Liu Tang

Tumor-Dissolving Decoction · 消瘤湯

Also known as: Xiao Liu Fang, Dissolve Tumor Decoction

A formula designed to address lumps, nodules, and masses by softening hardness, breaking up stagnation, and promoting the movement of Qi and Blood. It is commonly used in modern clinical practice for conditions such as thyroid nodules, lipomas, and other benign growths where Qi stagnation and Phlegm-Blood stasis have accumulated over time.

Origin Gǔ Jīn Fāng Yào Jí Jǐn (古今方药集锦, Collection of Ancient and Modern Formulas and Medicines) — Modern clinical formula (contemporary compilation)
Composition 11 herbs
Hai Zao
King
Hai Zao
Kun Bu
King
Kun Bu
Xia Ku Cao
Deputy
Xia Ku Cao
Mu Li ke
Deputy
Mu Li ke
Hai Fu Shi
Deputy
Hai Fu Shi
Huang Jie Zi
Deputy
Huang Jie Zi
San Leng
Assistant
San Leng
E zhu
Assistant
E zhu
+3
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Educational content Consult qualified TCM practitioners for diagnosis and treatment

Patterns Addressed

In TCM, symptoms don't appear randomly — they cluster into recognizable patterns of disharmony that reveal what's out of balance in the body. Xiao Liu Tang is designed to correct these specific patterns.

Why Xiao Liu Tang addresses this pattern

When Phlegm congeals and binds over time, it can form visible and palpable lumps, nodules, or masses beneath the skin or within the body's organs. Xiao Liu Tang directly targets this pattern through its core team of salty, Phlegm-softening herbs (Hai Zao, Kun Bu, Mu Li, Hai Fu Shi) that dissolve the material substance of congealed Phlegm. Xia Ku Cao and Huang Yao Zi add the ability to clear any Heat or toxins that have accumulated within the Phlegm nodule, while Mu Xiang keeps the Qi moving so that Phlegm cannot re-form.

A practitioner would look for one or more of these signs

Goiter

Thyroid enlargement or visible neck swelling

Lumps

Palpable lumps or nodules under the skin

Slippery Pulse
Greasy Tongue Coating

White or yellow greasy tongue coating

Commonly Prescribed For

These conditions can arise from the patterns above. A practitioner would consider Xiao Liu Tang when these conditions are specifically caused by those patterns — not for all cases of these conditions.

TCM Interpretation

In TCM, thyroid nodules and goiter are classified as 'ying liu' (瘿瘤), meaning neck lumps or tumors. They are understood as arising primarily from emotional frustration or long-term stress that causes the Liver Qi to stagnate. When Qi stagnation persists, it impairs the Spleen's ability to transform fluids, leading to Phlegm production. This Phlegm then rises and accumulates in the throat region along the Liver channel's pathway, gradually congealing into a visible or palpable mass. Over time, Blood stasis may also develop within the nodule, making it firmer and more difficult to resolve.

Why Xiao Liu Tang Helps

Xiao Liu Tang is particularly well-suited for thyroid conditions because its King herbs, Hai Zao and Kun Bu, have been used since the Tang dynasty specifically for neck masses and goiter. These iodine-rich seaweeds have a direct affinity for the throat area. Huang Yao Zi adds specific toxin-clearing action for thyroid tumors. Xia Ku Cao clears Liver Heat that often accompanies thyroid nodules (many patients experience irritability, eye dryness, or insomnia alongside the nodule). The stasis-breaking pair of San Leng and E Zhu prevents the nodule from becoming fixed and calcified, while Mu Xiang ensures that the Qi-moving dimension of treatment is covered.

Also commonly used for

Lumps

Lipomas and subcutaneous nodules

Breast Lumps

Breast fibroadenomas and fibrocystic changes

Ovarian Cysts

Ovarian cysts

Reactive Lymphadenopathy

Chronic lymph node enlargement (scrofula / 瘰疬)

What This Formula Does

Every TCM formula has a specific set of actions — here's what Xiao Liu Tang does in the body, explained in both everyday and TCM terms

Therapeutic focus

In practical terms, Xiao Liu Tang is primarily used to support these areas of health:

How It Addresses the Root Cause

TCM doesn't just suppress symptoms — it aims to resolve the underlying imbalance. Here's how Xiao Liu Tang works at the root level.

Xiao Liu Tang addresses the formation of benign masses, tumors, and nodules, which in TCM are understood as the result of intertwined Phlegm and Blood stasis (痰瘀互结, tan yu hu jie). The disease logic unfolds as follows:

Emotional stress, constitutional weakness, or longstanding illness can cause the Liver's Qi-moving function to become constrained. When Qi stagnates, two things happen simultaneously: Blood circulation slows and begins to congeal, and the Spleen's ability to transform and transport fluids weakens, allowing Dampness to accumulate and thicken into Phlegm. Over time, this stagnant Blood and congealed Phlegm bind together and lodge in specific locations, forming palpable masses. In women, these often settle in the Uterus (as fibroids) or the breast (as lumps); in either sex they may appear in the thyroid or as subcutaneous nodules. The Liver channel's pathway, which passes through the reproductive organs, the flanks, and the throat, explains why masses tend to develop along this trajectory.

Because the root cause involves both Phlegm and Blood stasis bound together by Qi stagnation, effective treatment must simultaneously soften and dissolve the hardened Phlegm, move Blood to break up stasis, and restore the free flow of Qi. Simply attacking one aspect while ignoring the others will not fully resolve the condition. This is the therapeutic logic behind Xiao Liu Tang's multi-pronged approach.

Formula Properties

Every formula has an inherent temperature, taste, and affinity for specific organs — these properties determine how it interacts with the body

Overall Temperature

Slightly Cool

Taste Profile

Predominantly salty, bitter, and acrid. Salty to soften hardness and dissolve masses, bitter to clear Heat and dry Dampness, acrid to move Qi and activate Blood circulation.

Channels Entered

Ingredients

11 herbs

The herbs that make up Xiao Liu Tang, organized by their role in the prescription

King — Main ingredient driving the formula
Deputy — Assists and enhances the King
Assistant — Supports or moderates other herbs
Envoy — Directs the formula to its target
Kings — Main ingredient driving the formula
Hai Zao

Hai Zao

Sargassum

Dosage 15 - 20g
Temperature Cold
Taste Bitter, Salty
Organ Affinity Kidneys, Liver, Stomach

Role in Xiao Liu Tang

Softens hardness and dissipates nodules. As a salty, cold seaweed, it directly targets Phlegm-nodule accumulations and is the primary herb for dissolving masses.
Kun Bu

Kun Bu

Kombu

Dosage 15 - 20g
Temperature Cold
Taste Salty
Organ Affinity Kidneys, Liver, Stomach

Role in Xiao Liu Tang

Works alongside Hai Zao to soften hardness and dissipate Phlegm-nodules. Together they form the core pair for dissolving masses and goiters.
Deputies — Assists and enhances the King
Xia Ku Cao

Xia Ku Cao

Heal-all spikes

Dosage 12 - 15g
Temperature Cold
Taste Bitter, Pungent
Organ Affinity Gallbladder, Liver

Role in Xiao Liu Tang

Clears Liver Fire and dissipates nodules. It particularly targets swollen lymph nodes and thyroid enlargement by clearing Heat-Phlegm that congeals into masses.
Mu Li ke

Mu Li ke

Oyster shells

Dosage 15 - 20g
Temperature Cold
Taste Salty
Organ Affinity Urinary Bladder, Gallbladder, Kidneys, Liver
Preparation Decoct first (先煎) for 20-30 minutes before adding other herbs

Role in Xiao Liu Tang

Softens hardness and dissipates nodules with its salty, astringent nature. Reinforces the King herbs in breaking down firm masses.
Hai Fu Shi

Hai Fu Shi

Pumice

Dosage 12 - 15g
Temperature Cold
Taste Salty
Organ Affinity Lungs, Stomach
Preparation Decoct first (先煎) for 20-30 minutes

Role in Xiao Liu Tang

Softens hardness and transforms Phlegm. Assists the King herbs in dissolving stubborn Phlegm accumulations that form the material basis of masses.
Huang Jie Zi

Huang Jie Zi

Brown mustard seeds

Dosage 12 - 15g
Temperature Warm
Taste Pungent
Organ Affinity Lungs

Role in Xiao Liu Tang

Resolves toxins and dissipates nodules. Has a specific affinity for thyroid masses and goiters and clears toxic Heat that contributes to mass formation.
Assistants — Supports or moderates other herbs
San Leng

San Leng

Common burreed tubers

Dosage 6 - 10g
Temperature Neutral
Taste Bitter, Pungent
Organ Affinity Spleen, Liver

Role in Xiao Liu Tang

Breaks Blood stasis and promotes movement of Qi. Paired with E Zhu to address the Blood stasis component of masses and accumulations.
E zhu

E zhu

Zedoary rhizomes

Dosage 6 - 10g
Temperature Warm
Taste Bitter, Pungent
Organ Affinity Spleen, Liver

Role in Xiao Liu Tang

Moves Qi and breaks Blood stasis. Works with San Leng to dissolve fixed masses by addressing both Qi stagnation and Blood stasis simultaneously.
Dang Gui

Dang Gui

Dong quai

Dosage 9 - 10g
Temperature Warm
Taste Pungent, Sweet
Organ Affinity Heart, Liver, Spleen

Role in Xiao Liu Tang

Nourishes and moves Blood. Prevents the strongly stasis-breaking herbs from damaging healthy Blood, and supports circulation to help disperse masses.
Chuan Lian Zi

Chuan Lian Zi

Sichuan chinaberries

Dosage 6 - 10g
Temperature Cold
Taste Bitter
Organ Affinity Spleen, Liver, Small Intestine
Preparation Dry-fried (炒) before use

Role in Xiao Liu Tang

Powerfully unblocks the channels and collaterals, disperses stagnation and reduces swelling. Its penetrating nature helps the other herbs reach deep-seated masses.
Envoy — Directs the formula to its target
Mu Xiang

Mu Xiang

Costus roots

Dosage 3 - 6g
Temperature Warm
Taste Bitter, Pungent
Organ Affinity Gallbladder, Large Intestine, Liver, Lungs, Spleen, Stomach

Role in Xiao Liu Tang

Moves Qi and prevents stagnation. Ensures that Qi circulates smoothly to support the dissolution of masses, and harmonizes the formula by preventing the heavy, sinking herbs from blocking the Middle Burner.

Why This Combination Works

How the herbs in Xiao Liu Tang complement each other

Overall strategy

Xiao Liu Tang addresses masses and nodules that arise from the intertwined pathology of Phlegm congelation, Blood stasis, and Qi stagnation. The formula simultaneously softens and dissolves the Phlegm-based structure of the mass, breaks up the Blood stasis that anchors it in place, and moves the Qi to prevent re-accumulation.

King herbs

Hai Zao (sargassum) and Kun Bu (kelp) are the King herbs. Both are salty and cold, and in TCM theory, the salty flavor has the ability to soften hardness. These two seaweeds have been paired since ancient times specifically to dissolve goiters, scrofula, and other Phlegm-nodule formations. Their combined action directly addresses the core pathology of congealed Phlegm forming a tangible mass.

Deputy herbs

Xia Ku Cao clears Liver Fire and dissipates nodules, addressing the Heat component that often accompanies prolonged stagnation. Sheng Mu Li and Hai Fu Shi reinforce the softening-hardness strategy from different angles: Mu Li is heavy and descending, anchoring the formula's action, while Hai Fu Shi transforms Phlegm from within. Huang Yao Zi adds the critical function of resolving toxins and has a particular affinity for thyroid and neck masses.

Assistant herbs

San Leng and E Zhu are a classic pair for breaking Blood stasis and moving Qi. They are reinforcing assistants that tackle the Blood stasis dimension of the mass, which the Phlegm-dissolving King and Deputy herbs cannot address alone. Dang Gui serves as a restraining assistant: it nourishes Blood to prevent the harsh stasis-breaking herbs from injuring healthy Blood. Chuan Shan Jia is a penetrating assistant that opens channels and collaterals, helping all other herbs reach deep-seated or encapsulated masses.

Envoy herbs

Mu Xiang moves Qi throughout the Middle Burner, preventing the many heavy, descending, and cloying herbs in this formula from causing digestive stagnation. It also directs the formula's action by ensuring smooth Qi flow, which is the prerequisite for both Phlegm transformation and Blood circulation.

Notable synergies

The Hai Zao and Kun Bu pair is the foundation of the formula's Phlegm-nodule dissolving power, with a synergy recognized in TCM for over a thousand years. The San Leng and E Zhu pair breaks both Qi and Blood stagnation simultaneously, with San Leng being stronger on Blood and E Zhu stronger on Qi. Dang Gui paired with the stasis-breakers creates a "break stasis without injuring Blood" dynamic that is essential for safe long-term use.

How to Prepare

Traditional preparation instructions for Xiao Liu Tang

Add the herbs to approximately 800ml of cold water. Soak for 30 minutes before cooking. Bring to a boil over high heat, then reduce to a gentle simmer and cook for 30 to 40 minutes. Strain and collect the liquid. Perform a second decoction with approximately 600ml of water for 20 to 30 minutes. Combine both decoctions and divide into two equal portions, taken warm in the morning and evening, ideally on an empty stomach or 30 minutes before meals.

Sheng Mu Li (raw oyster shell) should be decocted first (先煎) for 20 to 30 minutes before adding the remaining herbs, as it is a mineral/shell substance that requires prolonged cooking to extract its active constituents.

Common Modifications

How practitioners adapt Xiao Liu Tang for specific situations

Added
Chai Hu

6 - 9g, to spread Liver Qi and relieve stagnation in the throat area

Qing Pi

6 - 9g, to break Qi stagnation and direct the formula to the Liver channel

When Liver Qi stagnation is the dominant root cause, adding Chai Hu and Qing Pi addresses the underlying emotional constraint that drives Phlegm formation in the throat, making the mass-dissolving herbs more effective.

Educational content — always consult a qualified healthcare provider or TCM practitioner before using any herbal formula.

Contraindications

Situations where Xiao Liu Tang should not be used or requires extra caution

Avoid

Pregnancy. This formula contains Blood-moving and mass-dissolving herbs (such as San Leng, E Zhu, Tao Ren) that may stimulate uterine contractions and cause miscarriage.

Avoid

Active heavy menstrual bleeding or hemorrhage. The Blood-activating herbs in this formula can worsen bleeding. Treatment should wait until bleeding is controlled.

Caution

Severe Qi and Blood deficiency without concurrent tonification. The formula's attacking nature can further deplete a weakened constitution. If used in deficient patients, Qi and Blood tonics should be added.

Caution

Patients on anticoagulant or antiplatelet medications. The Blood-activating herbs may enhance anticoagulant effects and increase bleeding risk.

Caution

Thyroid conditions being treated with levothyroxine or anti-thyroid drugs. Hai Zao (Sargassum) and Kun Bu (Kelp) contain significant iodine, which can interfere with thyroid medication dosing.

Special Populations

Important considerations for pregnancy, breastfeeding, and pediatric use

Pregnancy

Contraindicated during pregnancy. This formula contains multiple herbs with strong Blood-activating and mass-dissolving properties. San Leng (Sparganium) and E Zhu (Curcuma zedoaria) are potent Blood-movers that can stimulate uterine contractions. Tao Ren (Peach kernel) is a well-known Blood stasis-breaking herb traditionally listed among pregnancy-prohibited substances. Hai Zao (Sargassum) and Kun Bu (Kelp) contain high levels of iodine that may affect fetal thyroid development. This formula should be strictly avoided throughout pregnancy.

Breastfeeding

Use with caution during breastfeeding. Several herbs in the formula have strong Blood-moving properties and their metabolites may pass into breast milk, potentially affecting the nursing infant. Hai Zao (Sargassum) and Kun Bu (Kelp) contain high iodine levels, which can transfer into breast milk and affect the infant's thyroid function. San Leng and E Zhu are potent herbs whose safety during lactation has not been established. If treatment of a mass is clinically necessary during breastfeeding, a practitioner should carefully weigh the benefits against potential risks to the infant and consider milder alternative formulas.

Children

This formula is generally not appropriate for children. Its strong Blood-activating and mass-dissolving herbs (San Leng, E Zhu, Tao Ren) are intended for established Phlegm-stasis masses that are uncommon in pediatric patients. Children's constitutions are considered delicate and not suited to such aggressive attacking strategies. If a child presents with a mass or nodule requiring treatment, a pediatric TCM specialist should be consulted to design an age-appropriate formula with gentler herbs and significantly reduced dosages.

Drug Interactions

If you are taking pharmaceutical medications, be aware of these potential interactions with Xiao Liu Tang

Anticoagulants and antiplatelet drugs (warfarin, heparin, aspirin, clopidogrel): The Blood-activating herbs in this formula, particularly San Leng, E Zhu, Tao Ren, and Dan Shen, may potentiate anticoagulant effects, increasing the risk of bleeding. Concurrent use requires close monitoring of coagulation parameters.

Thyroid medications (levothyroxine, methimazole, propylthiouracil): Hai Zao (Sargassum) and Kun Bu (Kelp) are rich in iodine, which can significantly alter thyroid hormone levels and interfere with the dosing of thyroid medications. Patients with thyroid conditions should have their thyroid function monitored closely.

Gan Cao (Licorice), if included in the formulation, may interact with antihypertensives (causing sodium retention and elevated blood pressure), corticosteroids (enhancing mineralocorticoid effects), and digoxin (through potassium depletion). Note: classical texts traditionally caution against combining Gan Cao with Hai Zao, as they are listed among the "eighteen incompatible combinations" (十八反), though many modern practitioners use them together deliberately.

Usage Guidance

Practical advice for getting the most out of Xiao Liu Tang

Best time to take

30 minutes after meals, twice daily (morning and evening), to reduce potential gastrointestinal irritation from the Blood-moving and mass-dissolving herbs.

Typical duration

Typically prescribed for 2-3 months as an initial course, then reassessed. Benign masses resolve slowly, so longer courses of 3-6 months are common, with formula adjustments every 2-4 weeks based on imaging and symptoms.

Dietary advice

Avoid cold, raw foods and iced drinks, as these can further congeal Blood and slow the dissolution of masses. Limit greasy, rich, and dairy-heavy foods, which tend to generate Phlegm and worsen the underlying Phlegm-stasis condition. Reduce alcohol consumption, as it produces Dampness and Heat. Favor lightly cooked vegetables, seaweed in small amounts, foods that gently move Qi such as hawthorn and tangerine peel tea, and Blood-nourishing foods like dark leafy greens and small amounts of red dates. Emotional regulation is also important: stress and frustration directly worsen Liver Qi stagnation, which is the root driver of mass formation.

Xiao Liu Tang originates from Gǔ Jīn Fāng Yào Jí Jǐn (古今方药集锦, Collection of Ancient and Modern Formulas and Medicines) Modern clinical formula (contemporary compilation)

Classical Texts

Key passages from the classical Chinese medical texts that first described Xiao Liu Tang and its clinical use

While Xiao Liu Tang itself is a modern clinical experience formula rather than a classical prescription, it draws on foundational principles from the classical tradition:

Huang Di Nei Jing, Su Wen:
「坚者削之」「结者散之」
"That which is hard should be pared away; that which is knotted should be dispersed."
These treatment principles from the Nei Jing form the theoretical foundation for the formula's approach to dissolving masses and nodules.

Jin Gui Yao Lue (Synopsis of the Golden Chamber):
「血不利则为水」
"When Blood does not flow smoothly, it transforms into water (fluid accumulation)."
This principle explains the interrelationship between Blood stasis and Phlegm-fluid accumulation that underlies the formation of masses, which this formula aims to address.

Chao Yuanfang, Zhu Bing Yuan Hou Lun (Treatise on the Origins of Disease):
The classical understanding of zheng jia (masses and accumulations) as arising from stagnant Qi and Blood congealing with Phlegm-Dampness provides the disease framework that informs this formula's design.

Historical Context

How Xiao Liu Tang evolved over the centuries — its origins, lineage, and place in the broader tradition of Chinese medicine

Xiao Liu Tang is not a classical formula from any single canonical text. Rather, it is a modern clinical experience formula (经验方, jing yan fang) that has been developed and refined by contemporary TCM practitioners, particularly those specializing in gynecology and oncology. Multiple versions exist under this name or closely related names.

The formula's theoretical roots, however, reach deep into the classical tradition. The treatment strategy of softening hardness and dissolving masses draws on principles articulated in the Huang Di Nei Jing. The use of seaweed-based herbs like Hai Zao and Kun Bu for treating goiters and nodules traces back to formulas like Hai Zao Yu Hu Tang (Sargassum Jade Flask Decoction) from the Wai Ke Zheng Zong (Orthodox Manual of External Diseases, 1617) by Chen Shigong. The Blood-moving approach echoes the work of Wang Qingren's Xue Fu Zhu Yu Tang and the Jin Gui Yao Lue's Gui Zhi Fu Ling Wan (Cinnamon Twig and Poria Pill), which Zhang Zhongjing designed specifically for uterine masses.

In modern practice, various noted gynecology specialists have contributed their own versions. The formula represents a synthesis of classical mass-dissolving strategies adapted to contemporary clinical needs, reflecting the TCM tradition of building on established principles while creating new prescriptions for specific clinical situations.