Hao Qin Qing Dan Tang

Artemisia and Scutellaria Decoction to Clear the Gallbladder · 蒿芩清胆汤

Also known as: Sweet Wormwood and Scutellaria Decoction to Clear the Gallbladder

A classical formula used to clear excess heat from the Gallbladder, drain dampness, and settle the Stomach when someone experiences alternating fever and chills (with fever predominating), a bitter taste in the mouth, nausea or vomiting of bitter or sour fluids, and chest or side discomfort. It is often applied in conditions like influenza, acute gastritis, and acute cholecystitis where damp-heat is a significant factor.

Origin 重订通俗伤寒论 (Chóng Dìng Tōng Sú Shāng Hán Lùn) by Yú Gēnchū (俞根初) — Qīng dynasty, 1776 CE
Composition 10 herbs
Qing Hao
King
Qing Hao
Huang Qin
King
Huang Qin
Zhu Ru
Deputy
Zhu Ru
Ban Xia
Deputy
Ban Xia
Zhi Ke
Deputy
Zhi Ke
Chen Pi
Deputy
Chen Pi
Chi Fu Ling
Assistant
Chi Fu Ling
Hua Shi
Envoy
Hua Shi
+2
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Explore composition

Educational content Consult qualified TCM practitioners for diagnosis and treatment

Patterns Addressed

In TCM, symptoms don't appear randomly — they cluster into recognizable patterns of disharmony that reveal what's out of balance in the body. Hao Qin Qing Dan Tang is designed to correct these specific patterns.

Why Hao Qin Qing Dan Tang addresses this pattern

This is the primary pattern this formula was designed for. When damp-heat becomes lodged in the Shaoyang (encompassing both the Gallbladder and the Triple Burner), it disrupts the Shaoyang's pivoting function. The Gallbladder's ministerial fire flares upward, the Triple Burner's waterways become obstructed, and body fluids congeal into phlegm. Qing Hao and Huang Qin directly target the damp-heat in the Shaoyang, venting it outward and clearing it internally. The Deputy herbs (Zhu Ru, Ban Xia, Zhi Ke, Chen Pi) resolve the resulting phlegm and descend rebellious Stomach Qi. Chi Fu Ling and Bi Yu San drain the dampness downward through urination. The entire formula works to restore the Shaoyang's pivoting function and clear the Triple Burner's waterways.

A practitioner would look for one or more of these signs

Alternating Fever And Chills

Fever predominates over chills (寒轻热重), distinct from Xiao Chai Hu Tang where chills and fever are more equal

Bitter Taste In The Mouth

Pronounced bitter taste in the mouth, often worse in the morning

Nausea

Vomiting of bitter, sour, or sticky yellow fluids

Feeling Of Chest Oppression

Stifling sensation in the chest and diaphragm area (膈闷)

Hypochondriac Pain

Distention and pain in the chest and sides

Dark Urine

Scanty, dark yellow urine indicating damp-heat in the lower burner

Commonly Prescribed For

These conditions can arise from the patterns above. A practitioner would consider Hao Qin Qing Dan Tang when these conditions are specifically caused by those patterns — not for all cases of these conditions.

Arises from: Damp-Heat

TCM Interpretation

In TCM, influenza is often understood as an invasion by external pathogenic factors. When the illness occurs during humid, warm seasons (late summer, early autumn), the external pathogen frequently combines with dampness. If the pathogen lodges in the Shaoyang level rather than being quickly expelled, it creates a pattern of damp-heat obstructing the Gallbladder and Triple Burner. The alternating fever and chills reflect the Shaoyang's half-exterior, half-interior nature. The nausea, bitter taste, and chest fullness indicate that Gallbladder heat is invading the Stomach and phlegm is forming. This is distinct from a purely Wind-Cold or Wind-Heat influenza, which would present with more pronounced exterior symptoms and less internal damp-heat.

Why Hao Qin Qing Dan Tang Helps

Hao Qin Qing Dan Tang addresses influenza with damp-heat by working on multiple levels simultaneously. Qing Hao vents the pathogenic heat outward through the Shaoyang exterior, helping to resolve the fever. Huang Qin clears the internal Gallbladder heat. The Deputy group (Zhu Ru, Ban Xia, Zhi Ke, Chen Pi) resolves the phlegm and nausea that accompany the infection. Chi Fu Ling and Bi Yu San drain the accumulated dampness downward through urination. Modern research has shown that this formula demonstrates significant anti-inflammatory effects, reducing inflammatory cytokines such as IL-6, IL-1β, and TNF-α, and has been used as part of the treatment strategy for damp-heat type respiratory infections.

Also commonly used for

Acute Gastritis

With bitter taste, nausea, and vomiting

Acute Nephritis

Acute icteric hepatitis with damp-heat predominance

Malaria

Malarial-type fevers with damp-heat features

Pneumonia

Acute pneumonia with damp-heat pattern

Dyspepsia

With Gallbladder-Stomach disharmony and damp-heat

Herpes Zoster Infection

Treated via the latent summerheat (伏暑) framework

Insomnia

When caused by Gallbladder heat and phlegm disturbing the Heart spirit

What This Formula Does

Every TCM formula has a specific set of actions — here's what Hao Qin Qing Dan Tang does in the body, explained in both everyday and TCM terms

Therapeutic focus

In practical terms, Hao Qin Qing Dan Tang is primarily used to support these areas of health:

TCM Actions

In TCM terminology, these are the specific therapeutic actions that Hao Qin Qing Dan Tang performs to restore balance in the body:

How It Addresses the Root Cause

TCM doesn't just suppress symptoms — it aims to resolve the underlying imbalance. Here's how Hao Qin Qing Dan Tang works at the root level.

This formula addresses a pattern where Damp-Heat becomes lodged in the Shaoyang (Lesser Yang) level, specifically affecting the Gallbladder and Triple Burner system, while also generating Phlegm turbidity that disrupts the Stomach. It is a more Heat-predominant and Dampness-complicated variant of the classic Shaoyang disorder described in the Shang Han Lun.

In TCM theory, the foot Shaoyang Gallbladder and hand Shaoyang Triple Burner function as a connected system. The Gallbladder stores and secretes bile to aid digestion, while the Triple Burner governs the waterways and the passage of Qi through all three body cavities. When an external pathogen (often summerheat-dampness or a lingering warm pathogen) enters this level, the Dampness obstructs the normal flow of Qi through the Triple Burner, and the trapped Heat causes the Gallbladder's ministerial fire to flare upward. This produces the characteristic symptom of alternating fever and chills that resembles malaria, but with fever clearly more pronounced than chills.

The blazing Gallbladder fire then invades the Stomach across the Wood-Earth relationship. The Stomach's normal descending function is disrupted, and body fluids subjected to Heat congeal into sticky Phlegm. This leads to nausea, vomiting of bitter or sour fluids, sticky yellow phlegm, chest fullness, and a stifling sensation in the diaphragm area. The bitter taste in the mouth is a hallmark of Gallbladder Heat rising. The tongue is red (Heat) with a thick greasy white or mixed-color coating (Dampness and Phlegm), and the pulse is typically wiry on the left (reflecting Gallbladder tension) and slippery on the right (reflecting Phlegm-Dampness in the Stomach). Because the pathology involves three aspects simultaneously — Heat in the Gallbladder, Phlegm turbidity in the middle burner, and Damp stagnation throughout the Triple Burner — treatment must address all three through a strategy known as 'separating and dispersing through multiple pathways' (分消走泄法, fēn xiāo zǒu xiè fǎ).

Formula Properties

Every formula has an inherent temperature, taste, and affinity for specific organs — these properties determine how it interacts with the body

Overall Temperature

Cool

Taste Profile

Predominantly bitter and slightly sweet, with aromatic and bland qualities — bitter to clear Heat and dry Dampness, aromatic to penetrate turbidity, bland to drain Dampness downward through urination.

Target Organs

Gallbladder Stomach San Jiao (Triple Burner) Spleen

Channels Entered

Ingredients

10 herbs

The herbs that make up Hao Qin Qing Dan Tang, organized by their role in the prescription

King — Main ingredient driving the formula
Deputy — Assists and enhances the King
Assistant — Supports or moderates other herbs
Envoy — Directs the formula to its target
Kings — Main ingredient driving the formula
Qing Hao

Qing Hao

Sweet wormwood

Dosage 4.5 - 6g
Temperature Cold
Taste Bitter (苦 kǔ), Acrid / Pungent (辛 xīn)
Organ Affinity Liver, Gallbladder, Kidneys

Role in Hao Qin Qing Dan Tang

Clears and vents heat from the Shaoyang level with its bitter, cold, and aromatic nature. It transparently releases pathogenic heat outward from the Gallbladder channel, acting as the lead herb for clearing summerheat and damp-heat lodged in the Shaoyang.
Huang Qin

Huang Qin

Chinese skullcap root

Dosage 4.5 - 9g
Temperature Cold
Taste Bitter (苦 kǔ)
Organ Affinity Lungs, Gallbladder, Spleen, Large Intestine, Small Intestine, Heart, Stomach

Role in Hao Qin Qing Dan Tang

Clears heat and dries dampness from the Gallbladder and Liver. Paired with Qing Hao, it both clears damp-heat internally and assists in venting pathogenic factors outward. The original text specifies using the young tender roots (青子芩) for their stronger heat-clearing action on the upper and middle burners.
Deputies — Assists and enhances the King
Zhu Ru

Zhu Ru

Bamboo shavings

Dosage 9g
Temperature Slightly Cool
Taste Sweet (甘 gān)
Organ Affinity Lungs, Stomach, Heart, Gallbladder

Role in Hao Qin Qing Dan Tang

Clears heat from the Gallbladder and Stomach, transforms phlegm, and stops vomiting. It directly addresses the nausea and vomiting of bitter or sticky fluids caused by Gallbladder heat invading the Stomach.
Ban Xia

Ban Xia

Pinellia tuber

Dosage 4.5g
Temperature Warm
Taste Acrid / Pungent (辛 xīn)
Organ Affinity Spleen, Stomach, Lungs

Role in Hao Qin Qing Dan Tang

Dries dampness, transforms phlegm, harmonizes the Stomach, and directs rebellious Qi downward. It addresses the phlegm-turbidity produced when Gallbladder heat causes body fluids to congeal. The original text specifies 'Xian Ban Xia' (仙半夏, processed form).
Zhi Ke

Zhi Ke

Bitter orange fruit

Dosage 4.5g
Temperature Slightly Cool
Taste Bitter (苦 kǔ), Acrid / Pungent (辛 xīn), Sour (酸 suān)
Organ Affinity Spleen, Stomach, Large Intestine, Lungs

Role in Hao Qin Qing Dan Tang

Moves Qi downward, opens the chest, and disperses phlegm-induced fullness. It works with Ban Xia and Chen Pi to relieve the stifling chest sensation and epigastric distention.
Chen Pi

Chen Pi

Tangerine peel

Dosage 4.5g
Temperature Warm
Taste Acrid / Pungent (辛 xīn), Bitter (苦 kǔ)
Organ Affinity Lungs, Spleen

Role in Hao Qin Qing Dan Tang

Regulates Qi, dries dampness, and transforms phlegm. It broadens the chest and smooths the flow of Qi in the middle burner, reinforcing the phlegm-resolving and Stomach-harmonizing effects of the other Deputy herbs.
Assistant — Supports or moderates other herbs
Chi Fu Ling

Chi Fu Ling

Red poria

Dosage 9g
Temperature Neutral
Taste Sweet (甘 gān), Bland (淡 dàn)
Organ Affinity Heart, Spleen, Urinary Bladder

Role in Hao Qin Qing Dan Tang

Promotes urination and drains damp-heat downward through the Bladder. Red Poria (Chi Fu Ling) is chosen over regular white Poria because of its added ability to clear heat from the Heart and conduct dampness downward, ensuring the pathogenic dampness has an exit route via the lower burner.
Envoys — Directs the formula to its target
Hua Shi

Hua Shi

Talcum

Dosage 6g (within 9g Bi Yu San)
Temperature Cold
Taste Sweet (甘 gān), Bland (淡 dàn)
Organ Affinity Stomach, Urinary Bladder
Preparation Wrapped in cheesecloth (包煎) as part of Bi Yu San

Role in Hao Qin Qing Dan Tang

The main component of Bi Yu San (碧玉散, Jasper Powder). It clears heat, promotes urination, and drains damp-heat downward through the Bladder, guiding Gallbladder fire to exit via the lower burner.
Gan Cao

Gan Cao

Licorice root

Dosage 1g (within 9g Bi Yu San)
Temperature Neutral
Taste Sweet (甘 gān)
Organ Affinity Heart, Lungs, Spleen, Stomach
Preparation Wrapped in cheesecloth (包煎) as part of Bi Yu San

Role in Hao Qin Qing Dan Tang

Within Bi Yu San, it harmonizes the other ingredients and protects the Stomach from the cold, bitter nature of the formula's heat-clearing herbs.
Qing Dai

Qing Dai

Natural indigo

Dosage 2g (within 9g Bi Yu San)
Temperature Cold
Taste Salty (咸 xián)
Organ Affinity Liver, Lungs
Preparation Wrapped in cheesecloth (包煎) as part of Bi Yu San

Role in Hao Qin Qing Dan Tang

Within Bi Yu San, it clears heat from the Liver channel and cools the Blood, adding an extra dimension of heat-clearing focused on the Liver-Gallbladder axis.

Why This Combination Works

How the herbs in Hao Qin Qing Dan Tang complement each other

Overall strategy

This formula targets a situation where damp-heat has become lodged in the Shaoyang (Gallbladder and Triple Burner), causing the Gallbladder's ministerial fire to flare, phlegm to accumulate as body fluids congeal, and the Stomach to rebel upward. The prescription simultaneously clears Gallbladder heat from above, resolves phlegm and harmonizes the Stomach in the middle, and drains damp-heat downward through urination.

King herbs

Qing Hao (Artemisia) and Huang Qin (Scutellaria) form the King pair that gives the formula its name. Qing Hao is bitter, cold, and aromatic, allowing it to transparently vent Shaoyang heat outward through the exterior. Huang Qin is bitter and cold, excelling at clearing Gallbladder heat and drying dampness internally. Together they address the core pathomechanism from two angles: Qing Hao leads heat out while Huang Qin clears it from within.

Deputy herbs

Zhu Ru, Ban Xia, Zhi Ke, and Chen Pi form a group drawn largely from Wen Dan Tang (Gallbladder-Warming Decoction). Zhu Ru clears phlegm-heat from the Gallbladder and Stomach and stops vomiting. Ban Xia dries dampness, transforms phlegm, and directs rebellious Stomach Qi downward. Zhi Ke and Chen Pi regulate Qi flow, open the chest, and resolve the stifling fullness and bloating. Together these four herbs dismantle the phlegm-turbidity that has formed when Gallbladder heat caused fluids to congeal.

Assistant herbs

Chi Fu Ling (red Poria) is a reinforcing assistant that promotes urination to drain damp-heat downward. Red Poria is chosen over white Poria specifically for its added ability to clear heat, making it better suited to a damp-heat pattern. It also supports the Spleen to prevent further dampness accumulation.

Envoy herbs

Bi Yu San (Jasper Powder, composed of Hua Shi, Gan Cao, and Qing Dai) serves as the envoy, directing the formula's action downward. Hua Shi clears heat and promotes urination, providing a downward exit route for the pathogenic damp-heat through the Bladder. Qing Dai adds Liver-Gallbladder heat-clearing. Gan Cao harmonizes the formula. Together with Chi Fu Ling, these ingredients ensure that damp-heat is guided out through the lower burner.

Notable synergies

The Qing Hao and Huang Qin pairing is the formula's signature: Qing Hao vents heat outward from the Shaoyang while Huang Qin clears it internally, creating a two-pronged attack on Gallbladder damp-heat that neither achieves alone. The Ban Xia, Zhu Ru, Chen Pi, and Zhi Ke grouping echoes Wen Dan Tang's phlegm-resolving and Stomach-harmonizing strategy, but with Zhi Ke (milder) substituted for Zhi Shi (stronger) and Chi Fu Ling replacing regular Fu Ling, making the group better suited to a heat-predominant pattern. The Chi Fu Ling and Bi Yu San pairing creates a strong downward-draining pathway that channels damp-heat out via the urine.

How to Prepare

Traditional preparation instructions for Hao Qin Qing Dan Tang

Decoct all herbs in water. The Bi Yu San (Jasper Powder, consisting of Hua Shi, Gan Cao, and Qing Dai) should be wrapped in cheesecloth before being added to the decoction pot with the rest of the ingredients. The original text does not specify a particular preparation method beyond water decoction (水煎服).

Common Modifications

How practitioners adapt Hao Qin Qing Dan Tang for specific situations

Added
Ru Xiang

6-9g, to move Qi and Blood and relieve pain

Yu Jin

9-15g, to move Liver Qi and resolve stasis in the Gallbladder

When Gallbladder damp-heat produces significant pain, adding Qi-and-Blood-moving herbs helps relieve pain by addressing the local stagnation that heat and dampness create in the Gallbladder area.

Educational content — always consult a qualified healthcare provider or TCM practitioner before using any herbal formula.

Contraindications

Situations where Hao Qin Qing Dan Tang should not be used or requires extra caution

Avoid

Shaoyang disorders from pure Cold pathogen without Damp-Heat (e.g. classic Xiao Chai Hu Tang presentation with equal chills and fever, no Dampness signs). This formula is specifically designed for Heat-predominant Shaoyang with Damp-Phlegm, not for Cold-type or balanced Shaoyang patterns.

Avoid

Yin deficiency with deficiency Heat. The bitter, cold, draining nature of this formula can further deplete Yin and body fluids in patients who already have pronounced Yin deficiency signs such as night sweats, a peeled tongue, or a thin rapid pulse.

Avoid

Spleen and Stomach Yang deficiency with cold signs such as loose stools from cold, poor appetite with aversion to cold food, and a pale puffy tongue. The cold and draining herbs in this formula would further injure already weakened digestive Yang.

Caution

Prolonged use beyond the acute phase. Once the Damp-Heat and Phlegm turbidity have cleared (fever subsides, nausea resolves, tongue coating normalizes), the formula should be discontinued or modified to avoid overcooling the middle burner.

Caution

Patients with significant Qi or Blood deficiency. The formula contains no tonifying herbs and its draining, clearing strategy may weaken an already depleted constitution. If some Damp-Heat is still present alongside deficiency, modifications with supportive herbs are needed.

Special Populations

Important considerations for pregnancy, breastfeeding, and pediatric use

Pregnancy

Use with caution during pregnancy. Ban Xia (Pinellia) is traditionally classified as a pregnancy-cautioned herb due to its potential to cause adverse effects on the fetus, though the processed form (Fa Ban Xia or Xian Ban Xia) used in this formula is considered less problematic than raw Ban Xia. Hua Shi (Talcum) in the Bi Yu San component is slippery and draining in nature, and its strong downward-directing action raises theoretical concern about promoting unwanted descent. This formula's overall cold, draining, and Dampness-clearing nature could also potentially compromise the Spleen Qi support needed during pregnancy. Should only be used during pregnancy if the Damp-Heat condition is severe and under close practitioner supervision, with dosage adjustments as needed.

Breastfeeding

Generally considered acceptable for short-term use during breastfeeding under practitioner guidance, but caution is warranted. Ban Xia (Pinellia) contains alkaloids that could theoretically transfer into breast milk in small amounts. Huang Qin (Scutellaria) is bitter and cold, and excessive use could affect the nursing mother's Spleen Qi and potentially reduce milk production. Hua Shi (Talcum) has a strong draining action that may contribute to fluid loss. If the mother has an active Damp-Heat condition requiring treatment, short-term use at standard doses is generally tolerated, but the infant should be monitored for any digestive disturbance such as loose stools. Discontinue promptly once the acute condition resolves.

Children

This formula can be used in children, particularly for pediatric febrile illnesses with Damp-Heat signs such as alternating fever, nausea, and a greasy tongue coating. Dosage must be reduced proportionally based on the child's age and weight: roughly one-quarter to one-third of the adult dose for children aged 3-6, and one-half for children aged 7-12. Ban Xia (Pinellia) should always be used in its properly processed form for pediatric patients. Because children's digestive systems are considered more delicate in TCM (the Spleen and Stomach are 'not yet fully developed'), extended use of this cold, draining formula can easily injure digestive function. It is best limited to the acute febrile phase and should be discontinued or modified as soon as the main symptoms resolve. Not recommended for infants under 1 year without specialist guidance.

Drug Interactions

If you are taking pharmaceutical medications, be aware of these potential interactions with Hao Qin Qing Dan Tang

Anticoagulants and antiplatelet drugs: Huang Qin (Scutellaria baicalensis) contains baicalin and baicalein, which have demonstrated antiplatelet and mild anticoagulant effects in pharmacological studies. Concurrent use with warfarin, heparin, or antiplatelet agents (aspirin, clopidogrel) may theoretically increase bleeding risk.

Antihypertensive medications: Hua Shi (Talcum) and Chi Fu Ling (Red Poria) promote urination and fluid drainage, which could potentiate the effects of diuretic antihypertensives or lead to electrolyte imbalances when combined with thiazide or loop diuretics.

Sedatives and CNS depressants: Huang Qin has shown mild sedative properties in animal studies. Combined use with benzodiazepines, barbiturates, or other CNS depressants may produce additive sedation.

Diabetes medications: Some research suggests Huang Qin may have mild hypoglycemic effects. Patients on insulin or oral hypoglycemics should monitor blood sugar more closely when using this formula.

Drug absorption effects: Hua Shi (Talcum) is an inorganic mineral that could theoretically adsorb concurrently administered oral medications in the GI tract, reducing their absorption. It is advisable to separate the timing of this formula from pharmaceutical drugs by at least 1-2 hours.

Usage Guidance

Practical advice for getting the most out of Hao Qin Qing Dan Tang

Best time to take

30 minutes to 1 hour after meals, twice daily (morning and evening), to minimize potential stomach irritation from the bitter, cold herbs.

Typical duration

Acute use: typically 3-7 days, reassessed as symptoms improve. Not intended for long-term use.

Dietary advice

Avoid greasy, fried, and rich foods, as these generate further Dampness and Phlegm, directly opposing the formula's Damp-clearing strategy. Avoid alcohol, which is hot and damp in nature and aggravates Gallbladder Heat. Avoid raw, cold foods such as ice cream, cold salads, and iced beverages, which can obstruct the Stomach Qi and impede the formula's ability to harmonize the middle burner. Sour foods (pickles, vinegar, citrus in excess) should be minimized, as sourness has a constricting nature that can trap pathogens. Favor light, easily digestible foods such as plain congee (rice porridge), steamed vegetables, and mung bean soup (which itself has mild Heat-clearing properties). Bland foods like winter melon, coix seed (Job's tears), and lotus seed are supportive as they gently drain Dampness. Bitter melon in small amounts is suitable as it echoes the formula's Heat-clearing action.

Hao Qin Qing Dan Tang originates from 重订通俗伤寒论 (Chóng Dìng Tōng Sú Shāng Hán Lùn) by Yú Gēnchū (俞根初) Qīng dynasty, 1776 CE

Classical Texts

Key passages from the classical Chinese medical texts that first described Hao Qin Qing Dan Tang and its clinical use

He Xiushan's (何秀山) commentary in the Chong Ding Tong Su Shang Han Lun (重订通俗伤寒论):

「足少阳胆,与手少阳三焦,合为一经。其气化一寄于胆中以化水谷,一发于三焦以行腠理。若受湿遏热郁,则三焦之气机不畅,胆中之相火乃炽。故以蒿、芩、竹茹为君,以清泄胆火。胆火炽,必犯胃而液郁为痰。故臣以枳壳、二陈,和胃化痰。然必下焦之气机通畅,斯胆中之相火清和。故又佐以碧玉,引相火下泄。使以赤苓,俾湿热下出,均从膀胱而去。此为和解胆经之良方。凡胸痞作呕,寒热如疟者,投无不效。」

Translation: "The foot Shaoyang Gallbladder and the hand Shaoyang Triple Burner combine as one channel system. Their Qi transformation is partly lodged in the Gallbladder to assist the digestion of food and water, and partly expressed through the Triple Burner to govern the interstices. If Dampness obstructs and Heat becomes pent up, the Qi mechanism of the Triple Burner becomes impeded and the ministerial fire in the Gallbladder flares. Therefore Artemisia (Qing Hao), Scutellaria (Huang Qin), and Bamboo Shavings (Zhu Ru) serve as the chief herbs to clear and drain Gallbladder fire. When Gallbladder fire blazes, it inevitably invades the Stomach and body fluids congeal into Phlegm. Therefore Bitter Orange (Zhi Ke) and the Two Aged [herbs, i.e. Chen Pi and Ban Xia] serve as deputies to harmonize the Stomach and transform Phlegm. Yet only when the Qi mechanism of the lower burner flows freely can the ministerial fire of the Gallbladder become clear and harmonious. Therefore Jasper Powder (Bi Yu San) assists by guiding ministerial fire to drain downward, while Red Poria (Chi Fu Ling) as envoy lets the Damp-Heat exit below, all leaving through the Bladder. This is an excellent formula for harmonizing the Gallbladder channel. Whenever there is chest stuffiness with vomiting, and alternating fever and chills resembling malaria, it is invariably effective."


Source text header in the Chong Ding Tong Su Shang Han Lun:

「蒿芩清胆汤 和解胆经法 俞氏经验方」

Translation: "Hao Qin Qing Dan Tang — Method for Harmonizing and Resolving the Gallbladder Channel — Yu's [Yu Genchu's] Experiential Formula."


Also from the Chong Ding Tong Su Shang Han Lun, regarding clinical application:

「暑湿疟……当辨其暑重于湿者为暑疟……暑疟,先与蒿芩清胆汤清其暑。」

Translation: "For summerheat-damp malaria… one must distinguish cases where summerheat predominates over dampness as summerheat malaria… For summerheat malaria, first give Hao Qin Qing Dan Tang to clear the summerheat."

Historical Context

How Hao Qin Qing Dan Tang evolved over the centuries — its origins, lineage, and place in the broader tradition of Chinese medicine

Hao Qin Qing Dan Tang was created by the Qing dynasty physician Yu Genchu (俞根初, also written 俞根), a renowned doctor from Shaoxing, Zhejiang province. He was the leading figure of what became known as the Shaoxing school of Shanghan (绍派伤寒), a regional tradition famous for its practical, clinically grounded approach to febrile disease. Yu Genchu's original work, Tong Su Shang Han Lun (通俗伤寒论, "Popular Guide to Cold Damage"), recorded his extensive clinical experience treating febrile and epidemic diseases in the humid, warm climate of southeastern China.

Yu Genchu's manuscript was not published during his lifetime. It was his friend and fellow physician He Xiushan (何秀山) who recognized the value of the work, annotated it with detailed commentaries (marked 「秀按」in the text), and arranged for its preservation. The version that came to be widely studied is the Chong Ding Tong Su Shang Han Lun (重订通俗伤寒论, "Revised Popular Guide to Cold Damage"), later re-edited by the modern scholar Xu Rongzhai (徐荣斋) in the 20th century. He Xiushan's commentary on this formula is particularly celebrated for its clear explanation of how the foot and hand Shaoyang channels interact, and why the formula's multi-directional strategy of 'separating and dispersing through multiple pathways' (分消走泄) is necessary.

Structurally, the formula is an ingenious reworking of Wen Dan Tang (温胆汤), the classical Phlegm-clearing formula, adapted for the specific situation where Shaoyang-level Heat and Dampness complicate the picture. By replacing the warming Sheng Jiang (fresh ginger) and tonifying Da Zao (jujube) of Wen Dan Tang with the cool, aromatic Qing Hao and bitter-cold Huang Qin, and adding the Damp-draining Bi Yu San (Jasper Powder) and Chi Fu Ling (Red Poria), Yu Genchu transformed a Phlegm-regulating formula into a targeted tool for Damp-Heat in the Shaoyang. This formula has been included in the Chinese government's official Ancient Classical Formula Directory (古代经典名方目录), recognizing its enduring clinical importance.