Dang Gui Yin Zi

Tangkuei Drink · 当归饮子

Also known as: Dang Gui Yin Zi Wan (当归饮子丸, Tangkuei Drink Pill)

A classical formula for chronic skin conditions such as itching, dryness, rashes, and hives caused by Blood deficiency and Wind. It works by nourishing the Blood to restore moisture to the skin while gently dispersing Wind to relieve itching. It is especially suited for people with long-standing skin problems who also show signs of fatigue, pallor, or dizziness.

Origin Chóng Dìng Yán Shì Jì Shēng Fāng (重订严氏济生方) by Yán Yònghé (严用和) — Southern Sòng dynasty, 1253 CE
Composition 10 herbs
Dang Gui
King
Dang Gui
Shu Di Huang
Deputy
Shu Di Huang
Bai Shao
Deputy
Bai Shao
Chuan Xiong
Deputy
Chuan Xiong
He Shou Wu
Deputy
He Shou Wu
Bai Jie Zi
Assistant
Bai Jie Zi
Fang Feng
Assistant
Fang Feng
Jing Jie
Assistant
Jing Jie
+2
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Educational content Consult qualified TCM practitioners for diagnosis and treatment

Patterns Addressed

In TCM, symptoms don't appear randomly — they cluster into recognizable patterns of disharmony that reveal what's out of balance in the body. Dang Gui Yin Zi is designed to correct these specific patterns.

Why Dang Gui Yin Zi addresses this pattern

When Blood is insufficient, the skin and tissues lose their nourishment. In TCM theory, Blood has the function of moistening and anchoring. When Blood is deficient, it fails to moisten the skin (leading to dryness, flaking, and roughness) and fails to anchor Wind (leading to itching that moves around or comes and goes). This creates 'internal Wind due to Blood deficiency,' where the itching is the Wind and the dryness is the Blood deficiency.

Dang Gui Yin Zi addresses this by heavily nourishing Blood through its Si Wu Tang core (Dang Gui, Sheng Di Huang, Bai Shao, Chuan Xiong) augmented by He Shou Wu, while simultaneously using Fang Feng, Jing Jie, and Bai Ji Li to calm and dispel the Wind that has already arisen. Huang Qi and Zhi Gan Cao tonify Qi to support Blood production and consolidate the body's defences. The nourishing action predominates over the dispersing action, which is why this formula is best suited for chronic rather than acute presentations.

A practitioner would look for one or more of these signs

Itchy Skin

Chronic, recurrent itching that worsens at night or with fatigue

Dark Skin

Rough, dry, flaky skin without obvious redness or weeping

Dull Pale Complexion

Pale or sallow complexion indicating Blood deficiency

Dizziness

Dizziness and lightheadedness from Blood failing to nourish the head

Insomnia

Difficulty sleeping, restless dreams from Blood failing to anchor the spirit

Pale Tongue

Pale tongue body with thin white coating

Commonly Prescribed For

These conditions can arise from the patterns above. A practitioner would consider Dang Gui Yin Zi when these conditions are specifically caused by those patterns — not for all cases of these conditions.

Arises from: Blood Deficiency

TCM Interpretation

TCM classifies eczema under the category of 'damp sores' (湿疮). In the acute phase, Dampness and Heat predominate, producing weeping, oozing lesions. However, when eczema becomes chronic and lingering, the picture shifts. Prolonged illness consumes Blood and Yin, leaving the skin dry, thickened, and rough. The Liver stores Blood and governs the sinews; the Spleen generates Blood and governs the flesh. When both are weakened over time, Blood becomes insufficient to nourish and moisten the skin. This dryness generates internal Wind, which manifests as persistent itching. The pattern then becomes one of Blood deficiency with Wind-dryness rather than Damp-Heat.

Why Dang Gui Yin Zi Helps

Dang Gui Yin Zi specifically targets the Blood-deficiency Wind-dryness pattern that characterizes chronic eczema. Its Si Wu Tang core (Dang Gui, Sheng Di Huang, Bai Shao, Chuan Xiong) replenishes and invigorates Blood to restore skin nourishment. He Shou Wu deepens the Blood-nourishing effect from the Liver-Kidney level. Bai Ji Li, Fang Feng, and Jing Jie dispel Wind and relieve itching. Huang Qi fortifies defensive Qi to reduce the skin's vulnerability to environmental triggers. Modern research has shown the formula can regulate immune markers including CD4+/CD8+ ratios and reduce inflammatory mediators like IL-31 in chronic eczema patients.

Also commonly used for

Atopic Dermatitis

Chronic atopic dermatitis with dry, itchy skin

Psoriasis

Psoriasis vulgaris with Blood-dryness pattern

Neurodermatitis

Neurodermatitis (lichen simplex chronicus)

Alopecia Areata

Blood deficiency type alopecia

Purpura

Elderly purpura from Blood deficiency and vessel fragility

Allergic Sinusitis

Allergic rhinitis with underlying Blood and Qi deficiency

What This Formula Does

Every TCM formula has a specific set of actions — here's what Dang Gui Yin Zi does in the body, explained in both everyday and TCM terms

Therapeutic focus

In practical terms, Dang Gui Yin Zi is primarily used to support these areas of health:

TCM Actions

In TCM terminology, these are the specific therapeutic actions that Dang Gui Yin Zi performs to restore balance in the body:

How It Addresses the Root Cause

TCM doesn't just suppress symptoms — it aims to resolve the underlying imbalance. Here's how Dang Gui Yin Zi works at the root level.

The disease pattern addressed by Dang Gui Yin Zi involves two interconnected problems: an underlying deficiency of Blood and an external invasion of Wind. In TCM theory, the skin depends on adequate Blood and Body Fluids for nourishment and moisture. When Blood becomes deficient, the skin loses its supply of moisture and nutrition, becoming dry, rough, and flaky. At the same time, Blood Deficiency leaves the body's defensive layer (Wei Qi) poorly supported and the interstices (the spaces between skin and muscle) loosely guarded, making a person vulnerable to external Wind pathogen invasion.

Wind is the pathogen most closely associated with itching in TCM. When Wind lodges in the skin of a Blood-deficient person, it cannot be expelled because there is not enough Blood to push it out. The classical teaching "to treat Wind, first treat the Blood; when the Blood flows, Wind naturally subsides" (治风先治血,血行风自灭) captures this logic. The Wind causes the itching and restlessness of the skin condition, while the Blood Deficiency causes the dryness, paleness of skin lesions, chronicity, and tendency for the condition to worsen at night (when Yin and Blood naturally recede). The original text attributes the condition to "Heart Blood stagnation with internally harbored Wind-Heat" (心血凝滞,内蕴风热), reflecting the classical view that the Heart governs the Blood and connects to the skin surface.

This creates a self-reinforcing cycle: Blood Deficiency allows Wind to persist, and the chronic presence of Wind further consumes and damages the Blood. The condition tends to be chronic and relapsing rather than acute, with dry rather than weepy skin lesions, and itching that is diffuse and migratory rather than fixed. The tongue is typically pale with a thin white coating, and the pulse is thin (fine) or rough, both signs pointing to Blood insufficiency.

Formula Properties

Every formula has an inherent temperature, taste, and affinity for specific organs — these properties determine how it interacts with the body

Overall Temperature

Slightly Warm

Taste Profile

Predominantly sweet and acrid (pungent), with a mild bitter note. Sweet to nourish Blood and tonify Qi, acrid to move Blood, dispel Wind, and open the skin surface.

Channels Entered

Ingredients

10 herbs

The herbs that make up Dang Gui Yin Zi, organized by their role in the prescription

King — Main ingredient driving the formula
Deputy — Assists and enhances the King
Assistant — Supports or moderates other herbs
Envoy — Directs the formula to its target
King — Main ingredient driving the formula
Dang Gui

Dang Gui

Chinese Angelica root

Dosage 9 - 12g
Temperature Warm
Taste Sweet (甘 gān), Acrid / Pungent (辛 xīn)
Organ Affinity Liver, Heart, Spleen

Role in Dang Gui Yin Zi

The chief Blood-nourishing herb. Dang Gui supplements and invigorates Blood, moistens dryness, and addresses the root cause of Blood deficiency that leaves the skin malnourished and vulnerable to Wind invasion.
Deputies — Assists and enhances the King
Shu Di Huang

Shu Di Huang

Prepared Rehmannia root

Dosage 9 - 15g
Temperature Slightly Warm
Taste Sweet (甘 gān)
Organ Affinity Liver, Kidneys

Role in Dang Gui Yin Zi

Nourishes Yin, cools Blood, and generates fluids. By using raw Rehmannia rather than prepared, the formula gains the ability to gently cool any residual Heat in the Blood layer while deeply moistening dry skin.
Bai Shao

Bai Shao

White peony root

Dosage 9 - 12g
Temperature Slightly Cool
Taste Bitter (苦 kǔ), Sour (酸 suān)
Organ Affinity Liver, Spleen

Role in Dang Gui Yin Zi

Nourishes Blood and preserves Yin, softens the Liver, and works with Dang Gui to strengthen the Blood-nourishing core of the formula (as part of the Si Wu Tang base).
Chuan Xiong

Chuan Xiong

Sichuan lovage rhizome

Dosage 6 - 9g
Temperature Warm
Taste Acrid / Pungent (辛 xīn)
Organ Affinity Liver, Gallbladder, Pericardium

Role in Dang Gui Yin Zi

Invigorates Blood circulation and moves Qi within the Blood. Prevents the rich Blood-nourishing herbs from causing stagnation, ensuring that fresh Blood reaches the skin surface.
He Shou Wu

He Shou Wu

Fleeceflower Root

Dosage 6 - 12g
Temperature Slightly Warm
Taste Bitter (苦 kǔ), Sweet (甘 gān), Astringent (涩 sè)
Organ Affinity Liver, Kidneys

Role in Dang Gui Yin Zi

Supplements Liver and Kidney essence-Blood, nourishes the Blood and moistens dryness. Reinforces the Blood-nourishing strategy from the Liver-Kidney axis, providing a deeper level of replenishment beyond the Si Wu Tang base.
Assistants — Supports or moderates other herbs
Bai Jie Zi

Bai Jie Zi

White mustard seed

Dosage 9 - 12g
Temperature Warm
Taste Acrid / Pungent (辛 xīn)
Organ Affinity Lungs, Stomach

Role in Dang Gui Yin Zi

Calms the Liver, disperses Wind, and stops itching. A key anti-itch herb that addresses Wind from both external and internal (Liver Wind) origins, bridging the formula's Blood-nourishing and Wind-dispelling actions.
Fang Feng

Fang Feng

Siler root

Dosage 6 - 9g
Temperature Slightly Warm
Taste Acrid / Pungent (辛 xīn), Sweet (甘 gān)
Organ Affinity Urinary Bladder, Liver, Spleen

Role in Dang Gui Yin Zi

Releases exterior Wind and stops itching. A gentle Wind-dispersing herb that expels pathogenic Wind from the skin surface without being overly drying or damaging to the Blood.
Jing Jie

Jing Jie

Schizonepeta

Dosage 6 - 9g
Temperature Slightly Warm
Taste Acrid / Pungent (辛 xīn), Aromatic (芳香 fāng xiāng)
Organ Affinity Lungs, Liver

Role in Dang Gui Yin Zi

Disperses Wind from the exterior and vents skin rashes. Works synergistically with Fang Feng to relieve itching and guide pathogenic Wind out through the skin surface.
Huang Qi

Huang Qi

Astragalus root

Dosage 6 - 15g
Temperature Slightly Warm
Taste Sweet (甘 gān)
Organ Affinity Spleen, Lungs

Role in Dang Gui Yin Zi

Tonifies Qi, strengthens the Wei (defensive) Qi, and consolidates the body surface. Prevents recurrent Wind invasion by reinforcing the body's outer defences. Also supports Dang Gui in generating Blood (Qi generates Blood) and has a classical action of 'supporting the righteous to expel toxins' (托毒).
Envoy — Directs the formula to its target
Gan Cao

Gan Cao

Licorice root

Dosage 3 - 6g
Temperature Neutral
Taste Sweet (甘 gān)
Organ Affinity Heart, Lungs, Spleen, Stomach

Role in Dang Gui Yin Zi

Tonifies Qi, harmonizes all the herbs in the formula, and moderates the dispersing nature of the Wind-releasing herbs. Serves as the coordinating envoy that balances the nourishing and dispersing actions.

Why This Combination Works

How the herbs in Dang Gui Yin Zi complement each other

Overall strategy

This formula addresses chronic skin conditions rooted in Blood deficiency with secondary Wind invasion. The core strategy follows the classical principle 'to treat Wind, first treat the Blood; when Blood flows freely, Wind will naturally subside' (治风先治血,血行风自灭). The prescription places greater emphasis on nourishing Blood (the root) than on dispersing Wind (the branch), making it ideal for lingering skin diseases in constitutionally deficient patients.

King herb

Dang Gui serves as the King herb, directly addressing the central problem of Blood deficiency. It supplements Blood, invigorates circulation, and moistens dryness. When Blood is abundant and flowing smoothly, the skin regains its nourishment, and internal Wind generated by Blood deficiency naturally subsides.

Deputy herbs

Sheng Di Huang, Bai Shao, and Chuan Xiong join Dang Gui to form Si Wu Tang (Four Substances Decoction), the foundational Blood-nourishing formula. Sheng Di Huang (raw Rehmannia) is used instead of Shu Di Huang (prepared Rehmannia) to add a cooling, Yin-nourishing dimension that addresses any residual Heat lodged in the Blood. He Shou Wu reinforces Blood nourishment from the Liver-Kidney level, adding depth and sustainability to the replenishment.

Assistant herbs

Bai Ji Li (reinforcing assistant) calms Liver Wind and relieves itching, bridging the internal Blood-nourishing and external Wind-dispersing strategies. Fang Feng and Jing Jie Sui (reinforcing assistants) gently release Wind from the skin surface and vent rashes outward without being overly harsh or drying. Huang Qi (reinforcing assistant) strengthens defensive Qi to consolidate the body surface, preventing Wind from re-entering, while also supporting Blood production through the mechanism of Qi generating Blood.

Envoy herb

Zhi Gan Cao harmonizes the entire formula, moderating the dispersing tendency of the Wind-releasing herbs and supporting the Qi-tonifying action of Huang Qi. Fresh ginger (added during decoction per the original instructions) further assists in warming and dispersing, helping guide the formula's action outward to the skin.

Notable synergies

Dang Gui paired with Huang Qi echoes the classic Dang Gui Bu Xue Tang combination, where Qi tonification powerfully drives Blood production. Fang Feng paired with Jing Jie is a well-known duo for dispelling Wind and relieving itching, their combined effect being stronger than either alone. The overall design balances tonification without trapping pathogens (益气固表不留邪) and disperses Wind without damaging the body's righteous Qi (疏风止痒不伤正).

How to Prepare

Traditional preparation instructions for Dang Gui Yin Zi

In the original text, the herbs are coarsely cut (㕮咀). Take 12g of the blended formula per dose, add approximately 220ml of water and 5 slices of fresh ginger (生姜). Decoct until reduced to about 180ml (roughly eight-tenths of the original volume). Strain and take warm, at any time of day without restriction.

In modern clinical practice, the formula is typically prepared as a standard decoction (水煎服). Combine all herbs in their full single-dose quantities, add approximately 600-800ml of water, bring to a boil, then simmer for 20-30 minutes. Strain and divide into 2 doses, taken warm morning and evening. Fresh ginger (3-5 slices) is commonly added as in the original method.

Common Modifications

How practitioners adapt Dang Gui Yin Zi for specific situations

Added
Suan Zao Ren

9-15g, nourishes Heart Blood and calms the spirit

Ye Jiao Teng

15-30g, nourishes Blood, calms the spirit, and has secondary anti-itch effects

Fu Shen

9-12g, calms the Heart and settles anxiety

The source text states this pattern involves the Heart (心血凝滞), and the classical teaching 'all itching and sores belong to the Heart' supports adding spirit-calming herbs. Suan Zao Ren and Ye Jiao Teng nourish Heart Blood to settle the spirit, directly improving sleep and reducing the nocturnal itch-scratch cycle.

Educational content — always consult a qualified healthcare provider or TCM practitioner before using any herbal formula.

Contraindications

Situations where Dang Gui Yin Zi should not be used or requires extra caution

Avoid

Pregnancy: the formula contains Blood-moving herbs (Dang Gui, Chuan Xiong) that may stimulate uterine activity. Should not be used during pregnancy.

Avoid

Skin conditions due to excess Dampness-Heat (heavy oozing, thick yellow exudate, swollen hot lesions). This formula is designed for Blood Deficiency with Wind-Dryness, not for Damp-Heat predominant conditions. Xiao Feng San or Long Dan Xie Gan Tang are more appropriate for those presentations.

Avoid

Known allergy or hypersensitivity to any ingredient in the formula.

Caution

Acute Wind-Heat skin eruptions with strong Heat signs (high fever, deep red rashes, thick yellow tongue coating). The warming and tonifying nature of this formula may aggravate Heat excess.

Caution

Spleen deficiency with significant Dampness (loose stools, heavy limbs, thick greasy tongue coating). The enriching, cloying Blood-nourishing herbs may worsen Dampness. Modify with Dampness-transforming herbs or address the Spleen first.

Caution

Patients taking anticoagulant or antiplatelet medications should use with caution due to the Blood-activating properties of Dang Gui and Chuan Xiong.

Special Populations

Important considerations for pregnancy, breastfeeding, and pediatric use

Pregnancy

Contraindicated during pregnancy. The formula contains Dang Gui (Angelica sinensis) and Chuan Xiong (Ligusticum chuanxiong), both of which activate Blood circulation and may stimulate uterine contractions. He Shou Wu (Polygonum multiflorum) also carries concerns during pregnancy due to potential hepatotoxicity. These herbs collectively pose a risk of adverse effects on the pregnancy. Women who are pregnant or planning to become pregnant should not use this formula without explicit guidance from a qualified practitioner.

Breastfeeding

Use with caution during breastfeeding. He Shou Wu (Polygonum multiflorum) is the primary concern, as it has known potential for hepatotoxicity, and its metabolites may transfer through breast milk. Dang Gui and Chuan Xiong are generally considered compatible with breastfeeding in moderate doses, but their Blood-activating properties warrant monitoring. The formula does not contain strongly toxic or purgative herbs, so brief supervised use may be acceptable if clinically indicated. Consult a qualified practitioner before use while nursing.

Children

Dang Gui Yin Zi can be used in children with appropriate dose reduction, as it has been studied in pediatric acute urticaria patients. General guidelines: children aged 6-12 should receive approximately half the adult dose; children under 6 require further reduction to roughly one-quarter to one-third of the adult dose. The formula is relatively gentle and well-tolerated, but He Shou Wu should be used cautiously in children due to its potential hepatotoxic effects. Monitor for any digestive upset, as the Blood-nourishing herbs can be cloying to immature digestive systems. Not recommended for infants under 1 year. A qualified pediatric TCM practitioner should supervise all use in children.

Drug Interactions

If you are taking pharmaceutical medications, be aware of these potential interactions with Dang Gui Yin Zi

Anticoagulants and antiplatelet agents (warfarin, heparin, aspirin, clopidogrel): Dang Gui and Chuan Xiong both have documented blood-activating properties and may enhance anticoagulant effects. Ligustilide and ferulic acid (active compounds in both herbs) have been shown to inhibit platelet aggregation. Concurrent use may increase bleeding risk.

Antihypertensives: Gan Cao (Glycyrrhiza/licorice) contains glycyrrhizin, which can cause sodium retention and potassium loss (pseudoaldosteronism), potentially counteracting antihypertensive medications. Although the dose of Gan Cao in this formula is small, patients on blood pressure medications should be monitored.

Digoxin and cardiac glycosides: The potassium-depleting effect of Gan Cao may increase sensitivity to digoxin toxicity.

Diuretics (especially potassium-wasting types): Combined potassium loss from Gan Cao and thiazide/loop diuretics may lead to hypokalemia.

Hepatotoxic medications: He Shou Wu (Polygonum multiflorum) has documented potential for hepatotoxicity, particularly in its raw (unprocessed) form. Avoid combining with other hepatotoxic drugs (acetaminophen in high doses, statins, methotrexate) or monitor liver function closely.

Immunosuppressants: Modern pharmacological research indicates that ingredients in this formula have immunomodulatory effects. Concurrent use with immunosuppressive drugs should be supervised to avoid unpredictable interactions.

Usage Guidance

Practical advice for getting the most out of Dang Gui Yin Zi

Best time to take

Warm, between meals (30-60 minutes after eating), twice daily. The original text specifies "not restricted by time" (不拘时候), indicating flexible dosing.

Typical duration

Typically prescribed for 4-8 weeks for chronic skin conditions, reassessed by practitioner. May be extended for several months in stubborn or recurrent cases with periodic evaluation.

Dietary advice

Avoid excessive consumption of spicy, greasy, fried, and heavily seasoned foods while taking this formula, as these can generate internal Heat and Wind that counteract the formula's Blood-nourishing effects. Alcohol should also be avoided, as it generates Damp-Heat and can aggravate skin conditions. Cold and raw foods should be limited to protect the Spleen's digestive function, which is essential for generating new Blood. Foods that nourish Blood are beneficial while taking this formula: dark leafy greens, beets, black sesame seeds, goji berries, red dates (jujubes), bone broth, and dark-colored fruits like mulberries and blackberries. Adequate hydration supports the formula's moistening action on the skin.

Dang Gui Yin Zi originates from Chóng Dìng Yán Shì Jì Shēng Fāng (重订严氏济生方) by Yán Yònghé (严用和) Southern Sòng dynasty, 1253 CE

Classical Texts

Key passages from the classical Chinese medical texts that first described Dang Gui Yin Zi and its clinical use

Original source text from the Yan Shi Ji Sheng Fang (严氏济生方, Yan's Formulas to Aid the Living):

「治心血凝滞,内蕴风热,发见皮肤,遍身疮疥,或肿或痒,或脓水浸淫,或发赤疹㾦㿔。」

Translation: "Treats stagnation of Heart Blood with internally harbored Wind-Heat manifesting on the skin as widespread sores and scabies, with either swelling or itching, oozing of pus and fluid, or the eruption of red rashes and papules."


Classical teaching on the treatment principle:

「治风先治血,血行风自灭。」

Translation: "To treat Wind, first treat the Blood. When the Blood circulates freely, Wind will naturally be extinguished." This principle underpins the entire design of Dang Gui Yin Zi and explains why a Blood-nourishing formula is used for a condition that presents with Wind symptoms like itching.


Formula mnemonic verse (方歌):

「当归饮子治血燥,病因皆是血虚耗,四物荆防与芪草,首乌蒺藜最重要。」

Translation: "Dang Gui Yin Zi treats Blood-Dryness; the cause in every case is Blood Deficiency and depletion. Si Wu Tang with Jing Jie, Fang Feng, Huang Qi, and Gan Cao, plus He Shou Wu and Bai Ji Li are the most important."

Historical Context

How Dang Gui Yin Zi evolved over the centuries — its origins, lineage, and place in the broader tradition of Chinese medicine

Dang Gui Yin Zi was created by the Song dynasty physician Yan Yonghe (严用和) and published in his influential text Ji Sheng Fang (济生方, Formulas to Aid the Living) in 1253 CE. Yan Yonghe was a prolific clinician who studied medicine for over fifty years, and his book compiled both classical formulas and his own clinical innovations, containing approximately 400 prescriptions across internal, external, and gynecological medicine. The Ji Sheng Fang is the same text that produced the famous Gui Pi Tang (Restore the Spleen Decoction), demonstrating Yan's particular interest in Blood and Qi supplementation.

The formula's clinical application was notably popularized by Zhu Danxi (朱丹溪) in the following century during the Jin-Yuan medical reform era. In modern times, the formula has become especially prominent in dermatology and is listed as Formula #37 in China's official "Catalogue of Classical Famous Formulas" (古代经典名方目录), a government-recognized list of traditional prescriptions prioritized for modern research and development. The original text was partially lost and later reconstructed: the current standard edition, the Chong Ding Yan Shi Ji Sheng Fang (重订严氏济生方), was published in 1980 based on content recovered from the Yongle Dadian encyclopedia and cross-referenced with Japanese editions and other historical compilations.

The formula has become one of the most commonly used prescriptions in TCM dermatology, particularly in Japan, Taiwan, and mainland China, where it is widely available as a patent medicine. Its design represents a paradigm of the TCM dermatological principle of treating skin diseases through Blood nourishment rather than purely attacking Wind.

Modern Research

A published study investigating the pharmacological effects or clinical outcomes of Dang Gui Yin Zi

1

Efficacy and safety of Dang Gui Yinzi combined with topical medications for psoriasis: A systematic review and meta-analysis (2025)

Efficacy and safety of Dang Gui Yinzi combined with topical medications for psoriasis: A systematic review and meta-analysis. Integrative Medicine Research, 2025. PROSPERO: CRD42025637050.

This systematic review and meta-analysis included 13 randomized controlled trials with 918 participants examining Dang Gui Yin Zi combined with topical medications for psoriasis. The combination therapy group showed significantly greater improvement in PASI (Psoriasis Area and Severity Index) scores compared to topical medications alone (MD = -3.26, 95% CI [-4.13 to -2.39]), and higher clinical efficacy rates (RR = 1.27, 95% CI [1.19 to 1.36]).

Link

Research on TCM formulas is growing but still limited by Western clinical trial standards. These studies provide emerging evidence and should be considered alongside practitioner expertise.