Formula

Dang Gui Yin Zi

Dang Gui Decoction | 当归饮子

Also known as:

Dong Quai Drink , Tangkuei Drink , Dang Gui Yin , Dang Gui Yin Zi Tang , Dong Guai & Tribulus

Properties

External Wind-dispersing formulas · Slightly Warm

Key Ingredients

Dang Gui

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

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About This Formula

Traditional Chinese Medicine background and properties

Formula Description

A classical formula for chronic skin conditions such as itching, dryness, rashes, and hives caused by Blood deficiency and Wind. It works by nourishing the Blood to restore moisture to the skin while gently dispersing Wind to relieve itching. It is especially suited for people with long-standing skin problems who also show signs of fatigue, pallor, or dizziness.

Formula Category

Main Actions

  • Nourishes Blood and moistens Dryness
  • Dispels Wind and Stops Itching
  • Tonifies Qi and consolidates the Exterior
  • Invigorates Blood and Dispels Stasis
  • Supplements the Liver and Kidneys

TCM Patterns

In TCM, symptoms don't appear randomly — they cluster into recognizable patterns of disharmony that reveal what's out of balance in the body. Dang Gui Yin Zi is traditionally associated with these specific patterns.

The following describes this formula's classification within Traditional Chinese Medicine theory and is provided for educational purposes only.

Why Dang Gui Yin Zi addresses this pattern

When Blood is insufficient, the skin and tissues lose their nourishment. In TCM theory, Blood has the function of moistening and anchoring. When Blood is deficient, it fails to moisten the skin (leading to dryness, flaking, and roughness) and fails to anchor Wind (leading to itching that moves around or comes and goes). This creates 'internal Wind due to Blood deficiency,' where the itching is the Wind and the dryness is the Blood deficiency.

Dang Gui Yin Zi addresses this by heavily nourishing Blood through its Si Wu Tang core (Dang Gui, Sheng Di Huang, Bai Shao, Chuan Xiong) augmented by He Shou Wu, while simultaneously using Fang Feng, Jing Jie, and Bai Ji Li to calm and dispel the Wind that has already arisen. Huang Qi and Zhi Gan Cao tonify Qi to support Blood production and consolidate the body's defences. The nourishing action predominates over the dispersing action, which is why this formula is best suited for chronic rather than acute presentations.

A practitioner would look for one or more of these signs

Itchy Skin

Chronic, recurrent itching that worsens at night or with fatigue

Dark Skin

Rough, dry, flaky skin without obvious redness or weeping

Dull Pale Complexion

Pale or sallow complexion indicating Blood deficiency

Dizziness

Dizziness and lightheadedness from Blood failing to nourish the head

Insomnia

Difficulty sleeping, restless dreams from Blood failing to anchor the spirit

Pale Tongue

Pale tongue body with thin white coating

How It Addresses the Root Cause

The disease pattern addressed by Dang Gui Yin Zi involves two interconnected problems: an underlying deficiency of Blood and an external invasion of Wind. In TCM theory, the skin depends on adequate Blood and Body Fluids for nourishment and moisture. When Blood becomes deficient, the skin loses its supply of moisture and nutrition, becoming dry, rough, and flaky. At the same time, Blood Deficiency leaves the body's defensive layer (Wei Qi) poorly supported and the interstices (the spaces between skin and muscle) loosely guarded, making a person vulnerable to external Wind pathogen invasion.

Wind is the pathogen most closely associated with itching in TCM. When Wind lodges in the skin of a Blood-deficient person, it cannot be expelled because there is not enough Blood to push it out. The classical teaching "to treat Wind, first treat the Blood; when the Blood flows, Wind naturally subsides" (治风先治血,血行风自灭) captures this logic. The Wind causes the itching and restlessness of the skin condition, while the Blood Deficiency causes the dryness, paleness of skin lesions, chronicity, and tendency for the condition to worsen at night (when Yin and Blood naturally recede). The original text attributes the condition to "Heart Blood stagnation with internally harbored Wind-Heat" (心血凝滞,内蕴风热), reflecting the classical view that the Heart governs the Blood and connects to the skin surface.

This creates a self-reinforcing cycle: Blood Deficiency allows Wind to persist, and the chronic presence of Wind further consumes and damages the Blood. The condition tends to be chronic and relapsing rather than acute, with dry rather than weepy skin lesions, and itching that is diffuse and migratory rather than fixed. The tongue is typically pale with a thin white coating, and the pulse is thin (fine) or rough, both signs pointing to Blood insufficiency.

Formula Properties

Temperature

Slightly Warm

Taste Profile

Predominantly sweet and acrid (pungent), with a mild bitter note. Sweet to nourish Blood and tonify Qi, acrid to move Blood, dispel Wind, and open the skin surface.

Target Organs
Heart Liver Spleen Kidneys
Channels Entered
Heart Liver Spleen Kidney

Formula Origin

Chóng Dìng Yán Shì Jì Shēng Fāng (重订严氏济生方) by Yán Yònghé (严用和)

This is just partial information on the formula's TCM properties. More detailed information is available on the formula's dedicated page

Ingredients in Dang Gui Yin Zi

Detailed information about each herb in Dang Gui Yin Zi and their roles

Kings
Deputies
Assistants
Envoys
Dang Gui
Dang Gui

Chinese Angelica root

Dosage: 9 - 12g

Temperature Warm
Taste Sweet (甘 gān), Acrid / Pungent (辛 xīn)
Organ Affinity Liver, Heart, Spleen
Parts Used Root (根 gēn)
Role in Dang Gui Yin Zi

The chief Blood-nourishing herb. Dang Gui supplements and invigorates Blood, moistens dryness, and addresses the root cause of Blood deficiency that leaves the skin malnourished and vulnerable to Wind invasion.

Shu Di Huang
Shu Di Huang

Prepared Rehmannia root

Dosage: 9 - 15g

Temperature Slightly Warm
Taste Sweet (甘 gān)
Organ Affinity Liver, Kidneys
Parts Used Tuber (块茎 kuài jīng / 块根 kuài gēn)
Role in Dang Gui Yin Zi

Nourishes Yin, cools Blood, and generates fluids. By using raw Rehmannia rather than prepared, the formula gains the ability to gently cool any residual Heat in the Blood layer while deeply moistening dry skin.

Bai Shao
Bai Shao

White peony root

Dosage: 9 - 12g

Temperature Slightly Cool
Taste Bitter (苦 kǔ), Sour (酸 suān)
Organ Affinity Liver, Spleen
Parts Used Root (根 gēn)
Role in Dang Gui Yin Zi

Nourishes Blood and preserves Yin, softens the Liver, and works with Dang Gui to strengthen the Blood-nourishing core of the formula (as part of the Si Wu Tang base).

Chuan Xiong
Chuan Xiong

Sichuan lovage rhizome

Dosage: 6 - 9g

Temperature Warm
Taste Acrid / Pungent (辛 xīn)
Organ Affinity Liver, Gallbladder, Pericardium
Parts Used Rhizome (根茎 gēn jīng)
Role in Dang Gui Yin Zi

Invigorates Blood circulation and moves Qi within the Blood. Prevents the rich Blood-nourishing herbs from causing stagnation, ensuring that fresh Blood reaches the skin surface.

He Shou Wu
He Shou Wu

Fleeceflower Root

Dosage: 6 - 12g

Temperature Slightly Warm
Taste Bitter (苦 kǔ), Sweet (甘 gān), Astringent (涩 sè)
Organ Affinity Liver, Kidneys
Parts Used Tuber (块茎 kuài jīng / 块根 kuài gēn)
Role in Dang Gui Yin Zi

Supplements Liver and Kidney essence-Blood, nourishes the Blood and moistens dryness. Reinforces the Blood-nourishing strategy from the Liver-Kidney axis, providing a deeper level of replenishment beyond the Si Wu Tang base.

Bai Jie Zi
Bai Jie Zi

White mustard seed

Dosage: 9 - 12g

Temperature Warm
Taste Acrid / Pungent (辛 xīn)
Organ Affinity Lungs, Stomach
Parts Used Seed (种子 zhǒng zǐ / 子 zǐ / 仁 rén)
Role in Dang Gui Yin Zi

Calms the Liver, disperses Wind, and stops itching. A key anti-itch herb that addresses Wind from both external and internal (Liver Wind) origins, bridging the formula's Blood-nourishing and Wind-dispelling actions.

Fang Feng
Fang Feng

Siler root

Dosage: 6 - 9g

Temperature Slightly Warm
Taste Acrid / Pungent (辛 xīn), Sweet (甘 gān)
Organ Affinity Urinary Bladder, Liver, Spleen
Parts Used Root (根 gēn)
Role in Dang Gui Yin Zi

Releases exterior Wind and stops itching. A gentle Wind-dispersing herb that expels pathogenic Wind from the skin surface without being overly drying or damaging to the Blood.

Jing Jie
Jing Jie

Schizonepeta

Dosage: 6 - 9g

Temperature Slightly Warm
Taste Acrid / Pungent (辛 xīn), Aromatic (芳香 fāng xiāng)
Organ Affinity Lungs, Liver
Parts Used Whole plant / Aerial parts (全草 quán cǎo)
Role in Dang Gui Yin Zi

Disperses Wind from the exterior and vents skin rashes. Works synergistically with Fang Feng to relieve itching and guide pathogenic Wind out through the skin surface.

Huang Qi
Huang Qi

Astragalus root

Dosage: 6 - 15g

Temperature Slightly Warm
Taste Sweet (甘 gān)
Organ Affinity Spleen, Lungs
Parts Used Root (根 gēn)
Role in Dang Gui Yin Zi

Tonifies Qi, strengthens the Wei (defensive) Qi, and consolidates the body surface. Prevents recurrent Wind invasion by reinforcing the body's outer defences. Also supports Dang Gui in generating Blood (Qi generates Blood) and has a classical action of 'supporting the righteous to expel toxins' (托毒).

Gan Cao
Gan Cao

Licorice root

Dosage: 3 - 6g

Temperature Neutral
Taste Sweet (甘 gān)
Organ Affinity Heart, Lungs, Spleen, Stomach
Parts Used Root (根 gēn)
Role in Dang Gui Yin Zi

Tonifies Qi, harmonizes all the herbs in the formula, and moderates the dispersing nature of the Wind-releasing herbs. Serves as the coordinating envoy that balances the nourishing and dispersing actions.

Modern Research (1 study)

  • Efficacy and safety of Dang Gui Yinzi combined with topical medications for psoriasis: A systematic review and meta-analysis (2025)
See all research on the formula page

Usage & Safety

How to use this formula and important safety information

Important Medical Disclaimer

The information provided here is for educational purposes only and is not intended as medical advice or to replace consultation with a qualified healthcare professional. This formula is a dietary supplement and has not been evaluated by the FDA. It is not intended to diagnose, treat, cure, or prevent any disease.

Always consult with a qualified healthcare provider, particularly if you are pregnant, nursing, have a medical condition, or are taking other medications. Discontinue use and consult your healthcare provider if you experience any adverse reactions.

Recommended Dosage

Instructions for safe storage and consumption

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Best Time to Take

Warm, between meals (30-60 minutes after eating), twice daily. The original text specifies "not restricted by time" (不拘时候), indicating flexible dosing.

Typical Duration

Typically prescribed for 4-8 weeks for chronic skin conditions, reassessed by practitioner. May be extended for several months in stubborn or recurrent cases with periodic evaluation.

Dietary Advice

Avoid excessive consumption of spicy, greasy, fried, and heavily seasoned foods while taking this formula, as these can generate internal Heat and Wind that counteract the formula's Blood-nourishing effects. Alcohol should also be avoided, as it generates Damp-Heat and can aggravate skin conditions. Cold and raw foods should be limited to protect the Spleen's digestive function, which is essential for generating new Blood. Foods that nourish Blood are beneficial while taking this formula: dark leafy greens, beets, black sesame seeds, goji berries, red dates (jujubes), bone broth, and dark-colored fruits like mulberries and blackberries. Adequate hydration supports the formula's moistening action on the skin.

Modern Usage

Dang Gui Yin Zi is a traditional Chinese medicine formula known for its ability to nourish the Blood, moisturize Dryness, clear Heat, and expel Wind. This formula can be particularly beneficial for individuals suffering from chronic skin conditions such as eczema, psoriasis, and urticaria, especially when itching intensifies at night.

Special Populations

Pregnancy

Contraindicated during pregnancy. The formula contains Dang Gui (Angelica sinensis) and Chuan Xiong (Ligusticum chuanxiong), both of which activate Blood circulation and may stimulate uterine contractions. He Shou Wu (Polygonum multiflorum) also carries concerns during pregnancy due to potential hepatotoxicity. These herbs collectively pose a risk of adverse effects on the pregnancy. Women who are pregnant or planning to become pregnant should not use this formula without explicit guidance from a qualified practitioner.

Breastfeeding

Use with caution during breastfeeding. He Shou Wu (Polygonum multiflorum) is the primary concern, as it has known potential for hepatotoxicity, and its metabolites may transfer through breast milk. Dang Gui and Chuan Xiong are generally considered compatible with breastfeeding in moderate doses, but their Blood-activating properties warrant monitoring. The formula does not contain strongly toxic or purgative herbs, so brief supervised use may be acceptable if clinically indicated. Consult a qualified practitioner before use while nursing.

Pediatric Use

Dang Gui Yin Zi can be used in children with appropriate dose reduction, as it has been studied in pediatric acute urticaria patients. General guidelines: children aged 6-12 should receive approximately half the adult dose; children under 6 require further reduction to roughly one-quarter to one-third of the adult dose. The formula is relatively gentle and well-tolerated, but He Shou Wu should be used cautiously in children due to its potential hepatotoxic effects. Monitor for any digestive upset, as the Blood-nourishing herbs can be cloying to immature digestive systems. Not recommended for infants under 1 year. A qualified pediatric TCM practitioner should supervise all use in children.

Drug Interactions

Anticoagulants and antiplatelet agents (warfarin, heparin, aspirin, clopidogrel): Dang Gui and Chuan Xiong both have documented blood-activating properties and may enhance anticoagulant effects. Ligustilide and ferulic acid (active compounds in both herbs) have been shown to inhibit platelet aggregation. Concurrent use may increase bleeding risk.

Antihypertensives: Gan Cao (Glycyrrhiza/licorice) contains glycyrrhizin, which can cause sodium retention and potassium loss (pseudoaldosteronism), potentially counteracting antihypertensive medications. Although the dose of Gan Cao in this formula is small, patients on blood pressure medications should be monitored.

Digoxin and cardiac glycosides: The potassium-depleting effect of Gan Cao may increase sensitivity to digoxin toxicity.

Diuretics (especially potassium-wasting types): Combined potassium loss from Gan Cao and thiazide/loop diuretics may lead to hypokalemia.

Hepatotoxic medications: He Shou Wu (Polygonum multiflorum) has documented potential for hepatotoxicity, particularly in its raw (unprocessed) form. Avoid combining with other hepatotoxic drugs (acetaminophen in high doses, statins, methotrexate) or monitor liver function closely.

Immunosuppressants: Modern pharmacological research indicates that ingredients in this formula have immunomodulatory effects. Concurrent use with immunosuppressive drugs should be supervised to avoid unpredictable interactions.

Contraindications

Avoid

Pregnancy: the formula contains Blood-moving herbs (Dang Gui, Chuan Xiong) that may stimulate uterine activity. Should not be used during pregnancy.

Avoid

Skin conditions due to excess Dampness-Heat (heavy oozing, thick yellow exudate, swollen hot lesions). This formula is designed for Blood Deficiency with Wind-Dryness, not for Damp-Heat predominant conditions. Xiao Feng San or Long Dan Xie Gan Tang are more appropriate for those presentations.

Avoid

Known allergy or hypersensitivity to any ingredient in the formula.

Caution

Acute Wind-Heat skin eruptions with strong Heat signs (high fever, deep red rashes, thick yellow tongue coating). The warming and tonifying nature of this formula may aggravate Heat excess.

Caution

Spleen deficiency with significant Dampness (loose stools, heavy limbs, thick greasy tongue coating). The enriching, cloying Blood-nourishing herbs may worsen Dampness. Modify with Dampness-transforming herbs or address the Spleen first.

Caution

Patients taking anticoagulant or antiplatelet medications should use with caution due to the Blood-activating properties of Dang Gui and Chuan Xiong.

Cautions & Warnings

Although this formula is typically safe for most individuals, it may cause side effects in some people. Pregnant women, nursing mothers, postpartum women, and those with liver disease should use the formula with caution.

As with any Chinese herbal remedy, it is advisable to seek guidance from a qualified TCM practitioner before beginning treatment.

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Manufacturing, supplier, and product specifications

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Treasure of the East

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