Formula Pill (Wan)

Da An Wan

Great Tranquility Pill · 大安丸

Also known as: Da An Wan (Danxi Xinfa)

A classical digestive formula used to relieve food accumulation (bloating, belching, poor appetite, nausea) while also strengthening a weak digestive system. It is essentially the well-known Bao He Wan with the addition of Bai Zhu to support the Spleen. This makes it especially appropriate for people, including children and the elderly, whose recurrent digestive troubles stem from an underlying weakness in their digestive capacity rather than just occasional overeating.

Origin Dan Xi Xin Fa (丹溪心法), Volume 5 — Yuán dynasty, ~1347 CE
Composition 8 herbs
Shan Zha
King
Shan Zha
Bai Zhu
King
Bai Zhu
Shen Qu
Deputy
Shen Qu
Ban Xia
Deputy
Ban Xia
Fu Ling
Deputy
Fu Ling
Chen Pi
Assistant
Chen Pi
Lai Fu Zi
Assistant
Lai Fu Zi
Lian Qiao
Assistant
Lian Qiao
Explore composition

Educational content Consult qualified TCM practitioners for diagnosis and treatment

Patterns Addressed

In TCM, symptoms don't appear randomly — they cluster into recognizable patterns of disharmony that reveal what's out of balance in the body. Da An Wan is designed to correct these specific patterns.

Why Da An Wan addresses this pattern

This is the primary pattern Da An Wan addresses. When overeating or consuming hard-to-digest foods overwhelms the Stomach's capacity, undigested food accumulates in the middle burner. Da An Wan resolves this by deploying three specialized digestive herbs (Shan Zha for meat and grease, Shen Qu for alcohol and fermented foods, Lai Fu Zi for grain and starch) to directly break down the accumulated food. Chen Pi and Ban Xia restore Qi movement and descend rebellious Stomach Qi. Unlike Bao He Wan, which purely dissolves stagnation, Da An Wan simultaneously strengthens the Spleen with Bai Zhu and Fu Ling to prevent recurrence, making it particularly appropriate when the food stagnation occurs against a backdrop of digestive weakness.

A practitioner would look for one or more of these signs

Abdominal Pain

Fullness and distension in the upper abdomen, worse after eating

Belching

Foul-smelling belching with a rotten or sour odor (嗳腐)

Loss Of Appetite

Aversion to food, especially after overeating

Nausea

Nausea or vomiting of undigested food

Loose Stools

Loose stools, sometimes with undigested food particles

Acid Reflux

Sour regurgitation (吞酸)

Commonly Prescribed For

These conditions can arise from the patterns above. A practitioner would consider Da An Wan when these conditions are specifically caused by those patterns — not for all cases of these conditions.

TCM Interpretation

In TCM, chronic indigestion is understood as a failure of the Spleen and Stomach to properly transform and transport food. The Spleen is responsible for extracting nourishment from food and moving it through the body. When the Spleen is weak, its transforming power is insufficient, and food sits in the Stomach without being properly broken down. This creates a vicious cycle: accumulated food further obstructs Qi flow in the middle burner, generating Dampness and sometimes Heat, which in turn further impairs the Spleen's function. The condition is worsened by irregular eating habits, consumption of greasy or cold foods, or emotional stress that disrupts digestion.

Why Da An Wan Helps

Da An Wan directly addresses both sides of chronic indigestion. Its food-dissolving herbs (Shan Zha, Shen Qu, Lai Fu Zi) actively break down whatever has accumulated, while Bai Zhu and Fu Ling rebuild the Spleen's digestive strength to prevent recurrence. Ban Xia and Chen Pi restore the normal downward movement of Stomach Qi and resolve the Dampness that stagnant food generates. Lian Qiao clears any Heat that has developed from prolonged fermentation. This dual approach of dissolving stagnation while tonifying the Spleen makes Da An Wan especially well suited for people who experience indigestion repeatedly rather than as a one-time event.

Also commonly used for

Loss Of Appetite

Reduced appetite in children or adults with weak digestion

Nausea

Nausea or vomiting related to food stagnation

Acid Reflux

Acid reflux or sour regurgitation from food accumulation

Loose Stools

Loose stools or diarrhea from impaired digestion

What This Formula Does

Every TCM formula has a specific set of actions — here's what Da An Wan does in the body, explained in both everyday and TCM terms

Therapeutic focus

In practical terms, Da An Wan is primarily used to support these areas of health:

TCM Actions

In TCM terminology, these are the specific therapeutic actions that Da An Wan performs to restore balance in the body:

How It Addresses the Root Cause

TCM doesn't just suppress symptoms — it aims to resolve the underlying imbalance. Here's how Da An Wan works at the root level.

Da An Wan addresses a pattern where food accumulation (食积, shi ji) sits in the Stomach and Spleen system, combined with an underlying weakness of the Spleen's transforming and transporting function. When someone overeats or consumes too much greasy, rich, or raw food, the Spleen and Stomach can become overwhelmed. The Stomach's job is to "ripen and rot" food, while the Spleen transforms it into usable nourishment and moves it onward. If too much food arrives at once, or the Spleen is already somewhat weak, the digestive process stalls.

When food sits and stagnates, several secondary problems develop. Stagnant food blocks the normal flow of Qi in the middle of the body, causing feelings of fullness, bloating, and pain. The accumulation can generate Dampness (since undigested food is essentially damp matter), and over time it may produce Heat, much like food that sits too long begins to ferment and spoil. This explains the sour, foul-smelling belching (嗳腐吞酸) and the thick, greasy tongue coating that practitioners look for. The blocked Qi can also cause the Stomach's natural downward movement to reverse, leading to nausea or vomiting.

What makes Da An Wan's situation distinct from simple food stagnation is the element of Spleen weakness. The Spleen is not strong enough to finish the job on its own, so merely breaking up the food stagnation (as Bao He Wan does) is not sufficient. The digestive system also needs support and strengthening to prevent the same problem from recurring. This is the core logic: resolve what has accumulated while simultaneously rebuilding the Spleen's capacity to handle future meals.

Formula Properties

Every formula has an inherent temperature, taste, and affinity for specific organs — these properties determine how it interacts with the body

Overall Temperature

Neutral

Taste Profile

Predominantly sour and pungent with mild bitter and sweet notes. The sour dissolves accumulation, the pungent moves stagnant Qi, the bitter clears Heat, and the sweet strengthens the Spleen.

Target Organs

Channels Entered

Ingredients

8 herbs

The herbs that make up Da An Wan, organized by their role in the prescription

King — Main ingredient driving the formula
Deputy — Assists and enhances the King
Assistant — Supports or moderates other herbs
Kings — Main ingredient driving the formula
Shan Zha

Shan Zha

Hawthorn berries

Dosage 12 - 18g
Temperature Warm
Taste Sour, Sweet
Organ Affinity Heart, Liver, Spleen, Stomach

Role in Da An Wan

The primary digestive herb in the formula. Its sour and warm nature excels at dissolving food stagnation, particularly from meat and greasy foods. Used at the heaviest dosage alongside Bai Zhu to directly address the core problem of accumulated food in the Stomach.
Bai Zhu

Bai Zhu

Atractylodes rhizomes

Dosage 12 - 18g
Temperature Warm
Taste Bitter, Sweet
Organ Affinity Spleen, Stomach
Preparation Dry-fried (炒白术) to enhance its Spleen-strengthening effect

Role in Da An Wan

The key addition that distinguishes Da An Wan from Bao He Wan. Its bitter, sweet, and warm nature tonifies Spleen Qi and strengthens the Spleen's ability to transform and transport food. Used at the same heavy dosage as Shan Zha, it addresses the underlying Spleen weakness that allows food to accumulate in the first place.
Deputies — Assists and enhances the King
Shen Qu

Shen Qu

Medicated leaven

Dosage 6 - 9g
Temperature Warm
Taste Pungent, Sweet
Organ Affinity Spleen, Stomach
Preparation Dry-fried (炒神曲)

Role in Da An Wan

A fermented preparation that supports digestion and helps break down stale, fermented food and alcohol-related stagnation. Works alongside Shan Zha and Lai Fu Zi to cover all types of food accumulation.
Ban Xia

Ban Xia

Crow-dipper rhizomes

Dosage 6 - 9g
Temperature Warm
Taste Pungent
Organ Affinity Lungs, Spleen, Stomach
Preparation Use processed form (制半夏)

Role in Da An Wan

Dries Dampness and transforms Phlegm that arises from impaired Spleen function. Also descends rebellious Stomach Qi to stop nausea and vomiting, a common symptom of food stagnation.
Fu Ling

Fu Ling

Poria-cocos mushrooms

Dosage 6 - 9g
Temperature Neutral
Taste Sweet
Organ Affinity Heart, Kidneys, Lungs, Spleen

Role in Da An Wan

Strengthens the Spleen and drains Dampness through its bland, sweet nature. Works synergistically with Bai Zhu to support Spleen function, while removing the Dampness that food stagnation generates.
Assistants — Supports or moderates other herbs
Chen Pi

Chen Pi

Tangerine peel

Dosage 3 - 6g
Temperature Warm
Taste Bitter, Pungent
Organ Affinity Lungs, Spleen

Role in Da An Wan

Regulates Qi and harmonizes the Stomach. Its aromatic nature cuts through turbidity and foul accumulation in the digestive tract, helping to relieve bloating and distension by promoting the smooth flow of Qi through the middle burner.
Lai Fu Zi

Lai Fu Zi

Radish seeds

Dosage 3 - 6g
Temperature Neutral
Taste Pungent, Sweet
Organ Affinity Lungs, Spleen, Stomach

Role in Da An Wan

Descends Qi and reduces food stagnation, particularly from grain and starchy foods. Also helps dissolve Phlegm and relieve distension in the chest and abdomen.
Lian Qiao

Lian Qiao

Forsythia fruits

Dosage 3 - 6g
Temperature Cool
Taste Bitter
Organ Affinity Heart, Lungs, Small Intestine

Role in Da An Wan

Clears Heat and disperses clumping. When food stagnates for a prolonged period, it tends to generate Heat. Lian Qiao addresses this secondary Heat while also helping to break up areas of accumulation.

Why This Combination Works

How the herbs in Da An Wan complement each other

Overall strategy

Da An Wan addresses the combined problem of food stagnation with underlying Spleen weakness. Where Bao He Wan is a pure food-dissolving formula, Da An Wan adds the crucial dimension of Spleen tonification, making it appropriate for patients whose weak digestion is the root cause of their recurrent food accumulation.

King herbs

Shan Zha and Bai Zhu share the highest dosage and together form the strategic core of the formula. Shan Zha's sour, warm nature powerfully dissolves food accumulation, especially from rich, greasy, or meaty foods. Bai Zhu's bitter, sweet, warm nature tonifies the Spleen and restores its transforming and transporting function. Together they represent the formula's dual approach: dissolve what has already accumulated, and strengthen the organ that failed to process it.

Deputy herbs

Shen Qu complements Shan Zha by dissolving stale, fermented food and alcohol-related accumulation. Ban Xia dries the Dampness that food stagnation generates and descends rebellious Stomach Qi to relieve nausea. Fu Ling reinforces Bai Zhu's Spleen-strengthening action while draining Dampness through urination. Together with Ban Xia and Chen Pi, Fu Ling echoes the structure of Er Chen Tang within the formula, addressing the Phlegm-Dampness dimension.

Assistant herbs

Chen Pi (reinforcing) regulates Qi flow in the middle burner, relieving bloating and helping the digestive herbs reach their target. Its aromatic nature also cuts through foul turbidity from fermented food. Lai Fu Zi (reinforcing) descends Qi and specifically dissolves grain and starchy food accumulation, covering a type of stagnation that Shan Zha and Shen Qu do not address as well. Lian Qiao (restraining) clears the Heat that inevitably develops when food sits and ferments in the digestive tract, preventing the stagnation from transforming into a more serious Heat condition.

Notable synergies

The Shan Zha, Shen Qu, and Lai Fu Zi trio is a classic combination that covers meat, alcohol, and grain stagnation respectively, ensuring no type of food accumulation is left unaddressed. The Bai Zhu and Fu Ling pairing is a foundational Spleen-tonifying combination that both strengthens the Spleen and resolves Dampness. The inclusion of Ban Xia with Chen Pi creates a Qi-regulating, Dampness-drying pair that prevents the tonifying herbs from creating further stagnation.

How to Prepare

Traditional preparation instructions for Da An Wan

Grind all ingredients into a fine powder. Form into pills using a rice porridge paste as the binding agent. The standard adult dose is 6 to 9 grams per serving, taken with warm water, between meals (on a relatively empty stomach). In modern practice, the formula may also be prepared as a decoction using proportionally reduced dosages.

Common Modifications

How practitioners adapt Da An Wan for specific situations

Added
Huang Lian

3 - 6g, clears Heat from the Stomach generated by prolonged food stagnation

Huang Qin

6 - 9g, clears Heat from the middle and upper burner

When food stagnation persists, it tends to generate Heat. Adding these bitter, cold herbs directly clears the accumulated Heat while the base formula dissolves the underlying stagnation.

Educational content — always consult a qualified healthcare provider or TCM practitioner before using any herbal formula.

Contraindications

Situations where Da An Wan should not be used or requires extra caution

Caution

Not suitable for people with Spleen and Stomach deficiency cold (without food stagnation). The formula's digestive herbs can further weaken an already depleted digestive system when there is no actual food accumulation to resolve.

Caution

Use with caution in cases of Yin deficiency with Heat. The drying nature of Ban Xia and Chen Pi can further deplete fluids in Yin-deficient patients.

Avoid

Not appropriate for severe, acute abdominal conditions (such as appendicitis or intestinal obstruction) that require emergency medical attention. Food stagnation formulas should not be used to mask symptoms of surgical emergencies.

Caution

Avoid in cases of acid reflux or gastric ulcers caused by excess Stomach acid rather than food accumulation. Shan Zha (hawthorn) is acidic and may worsen these conditions.

Special Populations

Important considerations for pregnancy, breastfeeding, and pediatric use

Pregnancy

Use with caution during pregnancy. Ban Xia (Pinellia) is traditionally classified among herbs that should be used cautiously in pregnancy due to its acrid, drying properties and historical classification as a pregnancy-caution herb. Lai Fu Zi (radish seed) has a downward-directing action on Qi that warrants care. While Da An Wan is a relatively mild digestive formula, pregnant women should consult a qualified practitioner before use. The formula is not considered absolutely contraindicated, but should only be taken under professional guidance and for short durations if needed.

Breastfeeding

Generally considered compatible with breastfeeding when used at standard doses for short periods. The herbs in this formula are primarily digestive in nature and are not known to have significant transfer through breast milk or adverse effects on lactation. Ban Xia (Pinellia) is processed (制半夏) in this formula, which reduces its toxicity substantially. However, as with any herbal medicine during breastfeeding, it is advisable to consult a practitioner and use for the shortest duration necessary.

Children

Da An Wan has a long history of use in pediatric practice and is considered particularly well-suited for children because it combines food-resolving action with Spleen-strengthening support. Children's digestive systems are naturally immature, making them prone to food stagnation combined with Spleen weakness. Dosage should be reduced according to age and body weight: for children under 3 years, approximately one-quarter to one-third of the adult dose; for children aged 3 to 7, approximately half the adult dose; and for children 7 to 14, approximately two-thirds of the adult dose. The pills can be crushed and dissolved in warm water for young children who cannot swallow them whole. This formula is preferable to Bao He Wan for pediatric food stagnation because the added Bai Zhu protects the child's delicate Spleen Qi while the other herbs clear the accumulated food.

Drug Interactions

If you are taking pharmaceutical medications, be aware of these potential interactions with Da An Wan

No major drug interactions have been extensively documented for Da An Wan in pharmacological literature. However, the following theoretical considerations apply:

  • Antacids and acid-suppressing medications (PPIs, H2 blockers): Shan Zha (hawthorn) is acidic in nature and could theoretically influence gastric pH. Taking Da An Wan alongside acid-reducing medications may produce conflicting effects on stomach acid levels.
  • Hawthorn and cardiovascular drugs: Shan Zha has documented mild cardiovascular effects (vasodilation, mild blood pressure lowering). Patients taking antihypertensives, digoxin, or other cardiac medications should exercise caution and inform their prescriber.
  • Absorption of other medications: As a formula that affects gastrointestinal motility and digestive function, Da An Wan may theoretically alter the absorption rate of concurrently administered oral medications. It is advisable to separate dosing by at least one to two hours.

Usage Guidance

Practical advice for getting the most out of Da An Wan

Best time to take

30 minutes to 1 hour after meals, taken with warm water. For acute indigestion, can also be taken when symptoms arise.

Typical duration

Short-term use: typically 3 to 7 days for acute food stagnation, reassessed if symptoms persist beyond one week.

Dietary advice

While taking Da An Wan, avoid the very foods that caused the problem: greasy, fried, and rich fatty foods; raw and cold foods (including cold drinks, ice cream, and excessive raw salads); and excessively sweet or sticky foods that are hard to digest. Alcohol should also be avoided as it generates Dampness and Heat. Instead, favor simple, easily digestible meals such as plain rice congee, steamed vegetables, and light soups. Eat smaller portions at regular intervals rather than large meals. Chew food thoroughly and avoid eating late at night. Once the food stagnation has cleared, gradually reintroduce a normal diet while maintaining moderate portion sizes.

Da An Wan originates from Dan Xi Xin Fa (丹溪心法), Volume 5 Yuán dynasty, ~1347 CE

Classical Texts

Key passages from the classical Chinese medical texts that first described Da An Wan and its clinical use

《朱丹溪医学全书》(Complete Medical Works of Zhu Danxi):

「大安丸,健脾胃,消饮食。山楂、白术各二两,茯苓、神曲、炒半夏各一两,陈皮、莱菔子(炒)、连翘各五钱。上末之,炊饼丸。一方无白术,名保和丸。」

Translation: "Da An Wan strengthens the Spleen and Stomach, and resolves food accumulation. Shan Zha and Bai Zhu, two liang each; Fu Ling, Shen Qu, and fried Ban Xia, one liang each; Chen Pi, Lai Fu Zi (fried), and Lian Qiao, five qian each. Grind into powder and form pills with steamed-bread paste. A version without Bai Zhu is called Bao He Wan."


《医方考》(Systematic Investigation of Formulas) by Wu Kun, Ming Dynasty:

「饮食伤脾,成鼓胀者,此方主之。鼓胀者,腹皮虚大,鼓之坚急而有声也。」

Translation: "When food intake injures the Spleen and leads to drum-like distention, this formula governs it. Drum-like distention means the abdominal wall becomes distended and large, and when tapped it feels firm and taut with a resonant sound."

Historical Context

How Da An Wan evolved over the centuries — its origins, lineage, and place in the broader tradition of Chinese medicine

Da An Wan was created by Zhu Danxi (朱丹溪, 1281–1358), one of the four great masters of the Jin-Yuan medical era, and recorded in his influential work Dan Xi Xin Fa (《丹溪心法》, Teachings of Danxi), Volume 5. The formula is fundamentally a modification of his other famous creation, Bao He Wan (保和丸, Harmony-Preserving Pill), with the addition of a generous dose of Bai Zhu (white atractylodes). As classical texts note, removing Bai Zhu from Da An Wan gives you Bao He Wan. This simple but important addition shifts the formula's strategy from pure food-dissolving to one that simultaneously supports the Spleen, making it "消中兼补" (resolving stagnation while supplementing).

The Ming Dynasty physician Wu Kun (吴昆) provided an elegant analysis of Da An Wan in his Yi Fang Kao (《医方考》, Systematic Investigation of Formulas, 1584), explaining how each herb in the formula counters a specific type of harmful food accumulation through the principle of opposite tastes overcoming pathological flavors. Later physicians continued to modify the formula. For instance, the Qing Dynasty text Za Bing Yuan Liu Xi Zhu (《杂病源流犀烛》) records a variant that removes Lai Fu Zi and adds Su Zi (perilla seed), Mai Ya (barley sprout), and Huang Lian (coptis) for cough with food stagnation. The formula became particularly valued in pediatric practice, as children's immature digestive systems are especially prone to food accumulation with underlying Spleen weakness.