Bu Fei E Jiao Tang

Ass-Hide Gelatin Decoction to Tonify the Lungs · 补肺阿胶汤

Also known as: Bu Fei E Jiao San (补肺阿胶散, Ass-Hide Gelatin Powder to Tonify the Lungs), E Jiao San (阿胶散), Bu Fei San (补肺散)

A classical formula designed to nourish and moisten the Lungs while gently clearing Heat. It is used for chronic dry cough with little phlegm, dry throat, or traces of blood in the sputum, caused by Lung Yin deficiency with internal Heat. Originally created for children, it is also widely used in adults.

Origin Xiao Er Yao Zheng Zhi Jue (小儿药证直诀) by Qian Yi (钱乙), compiled by Yan Xiaozhong (阎孝忠) — Sòng dynasty, 1119 CE
Composition 6 herbs
E Jiao
King
E Jiao
Ma Dou Ling
Deputy
Ma Dou Ling
Niu Bang Zi
Deputy
Niu Bang Zi
Xing Ren
Assistant
Xing Ren
Nuo Mi
Assistant
Nuo Mi
Gan Cao
Envoy
Gan Cao
Explore composition

Educational content Consult qualified TCM practitioners for diagnosis and treatment

Patterns Addressed

In TCM, symptoms don't appear randomly — they cluster into recognizable patterns of disharmony that reveal what's out of balance in the body. Bu Fei E Jiao Tang is designed to correct these specific patterns.

Why Bu Fei E Jiao Tang addresses this pattern

Lung Yin deficiency means the Lungs lack the moist, cooling fluids needed to keep the respiratory tract lubricated and functioning smoothly. Without adequate Yin, the Lungs become dry, and internal 'deficiency Heat' arises, much like a pot that overheats when the water inside evaporates. This dryness and Heat irritate the Lungs, causing a persistent dry cough, throat dryness, and scanty sticky phlegm. If the Heat damages the delicate blood vessels in the Lungs, small amounts of blood may appear in the sputum.

Bu Fei E Jiao Tang directly replenishes Lung Yin through E Jiao's rich moistening action, while Ma Dou Ling and Niu Bang Zi gently clear the deficiency Heat that has developed. Xing Ren restores the Lung's natural downward Qi movement, relieving cough and wheezing. Nuo Mi and Zhi Gan Cao support digestion so the body can produce the fluids the Lungs need. The formula treats both the root (Yin deficiency) and the branch (Heat, cough, bleeding) simultaneously.

A practitioner would look for one or more of these signs

Chronic Coughing

Dry cough, often worse at night or in dry environments

Wheezing

Laboured breathing with a feeling of shortness of breath

Dry Throat

Persistent dryness and irritation in the throat

Bloody Sputum

Small streaks of blood in scanty phlegm

Scanty Phlegm

Little phlegm, or phlegm that is sticky and hard to expectorate

Red Tongue

Red tongue body with little or no coating

Rapid Pulse

Thin, rapid pulse (细数脉)

Commonly Prescribed For

These conditions can arise from the patterns above. A practitioner would consider Bu Fei E Jiao Tang when these conditions are specifically caused by those patterns — not for all cases of these conditions.

TCM Interpretation

In TCM, a lingering cough that persists long after the initial illness has resolved often points to depletion of Lung Yin. The original infection may have been caused by external Wind-Heat or Wind-Cold, but the illness consumed the Lung's Yin fluids. Without sufficient moisture, the Lungs cannot perform their 'descending and purifying' function smoothly. The resulting dryness constantly irritates the airways, producing a dry, hacking cough that is often worse at night when Yin naturally predominates. Over time, this deficiency Heat can damage the Lung's delicate blood vessels, producing traces of blood in the sputum.

Why Bu Fei E Jiao Tang Helps

Bu Fei E Jiao Tang addresses post-infectious chronic cough by rebuilding the Lung moisture that was depleted during illness. E Jiao provides deep Yin nourishment and directly moistens the dry Lung tissue. Ma Dou Ling and Niu Bang Zi clear any lingering Heat and open the airways, while Xing Ren restores the normal downward Qi flow that stops the cough reflex. Nuo Mi and Zhi Gan Cao strengthen digestion so the body can continue producing the fluids the Lungs need for long-term recovery.

Also commonly used for

Bronchiectasis

Especially when presenting with blood-streaked sputum

Pulmonary Tuberculosis

Adjunctive support for the Yin deficiency presentation

Asthma

Dry-type asthma with Yin deficiency

Whooping Cough

In the later, deficiency stage

Pharyngitis

Chronic dry pharyngitis with Yin deficiency

What This Formula Does

Every TCM formula has a specific set of actions — here's what Bu Fei E Jiao Tang does in the body, explained in both everyday and TCM terms

Therapeutic focus

In practical terms, Bu Fei E Jiao Tang is primarily used to support these areas of health:

TCM Actions

In TCM terminology, these are the specific therapeutic actions that Bu Fei E Jiao Tang performs to restore balance in the body:

How It Addresses the Root Cause

TCM doesn't just suppress symptoms — it aims to resolve the underlying imbalance. Here's how Bu Fei E Jiao Tang works at the root level.

This formula addresses a pattern where the Lungs have become depleted of their nourishing Yin fluids, and internal Heat has developed as a consequence. In TCM theory, the Lungs are a "delicate organ" (娇脏, jiāo zàng) that depends on adequate moisture to perform their functions of governing respiration and descending Qi. When Lung Yin becomes insufficient, whether from chronic illness, prolonged cough, or lingering pathogenic Heat that was never fully cleared, the Lungs lose their natural lubrication. Without this moisture, they become dry and irritated, and a kind of "deficiency Heat" (虚热) flares up.

This deficiency Heat scorches whatever remaining fluids are left, producing a dry cough with little or no sputum, a dry and sore throat, and a hoarse voice. The Lung Qi, which normally descends smoothly, rebels upward because the dryness prevents proper function, resulting in wheezing and labored breathing. If the condition persists, the Heat can damage the delicate blood vessels (Lung collaterals), causing blood to appear in the sputum. The tongue is red with scant coating (reflecting Yin depletion), and the pulse is thin and rapid (reflecting both insufficient fluids and the presence of Heat).

The treatment principle follows the logic of "nourishing what is deficient at the root while clearing what is excessive at the branch." The root problem is Lung Yin depletion, which must be replenished. The branch problem is the Heat and rebellious Qi, which must be cleared and redirected downward. Additionally, because in Five Phase theory Earth (Spleen) is the mother of Metal (Lungs), strengthening the Spleen indirectly supports the Lungs' recovery, a strategy known as "cultivating Earth to generate Metal" (培土生金).

Formula Properties

Every formula has an inherent temperature, taste, and affinity for specific organs — these properties determine how it interacts with the body

Overall Temperature

Slightly Cool

Taste Profile

Predominantly sweet and slightly bitter — sweet from E Jiao, Gan Cao, and glutinous rice to nourish and tonify; mildly bitter and pungent from the clearing and dispersing herbs to address Lung Heat.

Channels Entered

Ingredients

6 herbs

The herbs that make up Bu Fei E Jiao Tang, organized by their role in the prescription

King — Main ingredient driving the formula
Deputy — Assists and enhances the King
Assistant — Supports or moderates other herbs
Envoy — Directs the formula to its target
King — Main ingredient driving the formula
E Jiao

E Jiao

Donkey-hide gelatin

Dosage 9 - 15g
Temperature Neutral
Taste Sweet (甘 gān)
Organ Affinity Lungs, Liver, Kidneys
Preparation Stir-fried with bran (麸炒); dissolved separately in the strained decoction (烊化)

Role in Bu Fei E Jiao Tang

Sweet and neutral in nature, E Jiao is the principal herb, used at the heaviest dosage. It nourishes Yin and moistens the Lungs, supplements Blood, and stops bleeding. It directly addresses the core problem of Lung Yin depletion and is particularly important when there is blood-streaked sputum from damaged Lung vessels.
Deputies — Assists and enhances the King
Ma Dou Ling

Ma Dou Ling

Aristolochia Fruit

Dosage 3 - 6g
Temperature Cold
Taste Bitter (苦 kǔ), Acrid / Pungent (辛 xīn)
Organ Affinity Lungs, Large Intestine
Preparation Dry-roasted (焙)

Role in Bu Fei E Jiao Tang

Clears Heat from the Lungs, transforms Phlegm, and calms coughing. It assists the King herb by directly addressing the Lung Heat that is consuming Yin fluids and driving the cough. Note: Ma Dou Ling contains aristolochic acid and has been restricted or removed from clinical use in many regions due to kidney toxicity concerns. Modern practitioners often substitute Sang Bai Pi, Zhi Mu, or Qian Hu.
Niu Bang Zi

Niu Bang Zi

Burdock fruit

Dosage 3 - 6g
Temperature Cold
Taste Acrid / Pungent (辛 xīn), Bitter (苦 kǔ)
Organ Affinity Lungs, Stomach
Preparation Dry-fried until fragrant (炒香)

Role in Bu Fei E Jiao Tang

Disperses Lung Qi, clears Heat, resolves Phlegm, and benefits the throat. While E Jiao nourishes downward, Niu Bang Zi provides a lifting, dispersing action that opens congestion in the Lungs and throat, ensuring that Lung Qi flows smoothly despite the rich, sticky nature of the King herb.
Assistants — Supports or moderates other herbs
Xing Ren

Xing Ren

Bitter apricot kernel

Dosage 3 - 6g
Temperature Slightly Warm
Taste Bitter (苦 kǔ)
Organ Affinity Lungs, Large Intestine
Preparation Remove skin and tips, dry-fried (去皮尖, 炒)

Role in Bu Fei E Jiao Tang

Descends Lung Qi, stops coughing, and calms wheezing. It supports the formula's ability to restore the normal downward movement of Lung Qi that has become rebellious due to Yin deficiency and Heat. Its moistening quality also complements E Jiao in lubricating dryness.
Nuo Mi

Nuo Mi

Glutinous rice

Dosage 6 - 9g
Temperature Warm
Taste Sweet (甘 gān)
Organ Affinity Spleen, Stomach, Lungs
Preparation Dry-fried (炒)

Role in Bu Fei E Jiao Tang

Tonifies the Spleen and benefits the Lungs. Together with Gan Cao, it supports the Spleen (the 'mother' of the Lungs in Five Element theory), ensuring that the body can generate the Qi and fluids needed to restore the Lungs. It also protects the Stomach from the rich, cloying nature of E Jiao.
Envoy — Directs the formula to its target
Gan Cao

Gan Cao

Licorice root

Dosage 1.5 - 3g
Temperature Neutral
Taste Sweet (甘 gān)
Organ Affinity Heart, Lungs, Spleen, Stomach

Role in Bu Fei E Jiao Tang

Honey-prepared licorice tonifies the Spleen and benefits Lung Qi, while harmonising all the other herbs in the formula. Working with Nuo Mi, it strengthens the digestive system to support the Lungs and prevents the formula's enriching herbs from burdening the Stomach.

Why This Combination Works

How the herbs in Bu Fei E Jiao Tang complement each other

Overall strategy

This formula addresses Lung Yin deficiency with internal Heat by combining rich Yin-nourishing substances with gentle Heat-clearing and Qi-descending herbs. The strategy is primarily to supplement what is lacking (Lung Yin) while secondarily clearing the Heat that arises from this deficiency, restoring the Lung's normal descending function.

King herbs

E Jiao is the sole King herb, used at the highest dosage. Its sweet, neutral, and sticky (viscous) nature makes it ideal for deeply nourishing Lung Yin and replenishing Blood. It also has a direct hemostatic action that addresses any bleeding from damaged Lung vessels. As the formula is named after it, E Jiao defines the entire therapeutic direction.

Deputy herbs

Ma Dou Ling clears Heat from the Lungs and calms coughing by descending rebellious Qi. Niu Bang Zi disperses Lung Qi, clears Heat, and benefits the throat. Together, these two Deputies address the Heat component of the pattern and ensure that Lung Qi can circulate properly. Their descending and dispersing actions (降中寓升) prevent the rich, sticky King herb from causing stagnation.

Assistant herbs

Xing Ren (reinforcing assistant) descends Lung Qi and stops coughing, directly supporting the Deputies in restoring the normal downward movement of Lung Qi. Nuo Mi (reinforcing assistant) tonifies the Spleen and nourishes Stomach fluids, applying the Five Element principle of 'nourishing Earth to generate Metal' (培土生金), meaning that strengthening digestion helps rebuild Lung function.

Envoy herbs

Zhi Gan Cao (honey-prepared licorice) harmonises all the herbs in the formula while also contributing to the Spleen-tonifying strategy alongside Nuo Mi. It ensures the other herbs work together smoothly and protects the middle digestive system from the cloying nature of E Jiao.

Notable synergies

E Jiao paired with Xing Ren provides both nourishment and gentle descent: E Jiao enriches Yin while Xing Ren ensures that this enrichment does not stagnate Lung Qi. Ma Dou Ling paired with Niu Bang Zi creates a comprehensive Lung Heat-clearing duo, one descending and one dispersing, so that Heat is vented from the Lungs without trapping it. Nuo Mi paired with Zhi Gan Cao applies the 'cultivate Earth to generate Metal' principle, ensuring the Spleen can support the Lung's recovery.

How to Prepare

Traditional preparation instructions for Bu Fei E Jiao Tang

The original preparation is as a powder (散). Grind all ingredients into a fine powder. Take 3 to 6 grams per dose, decoct in one cup of water until reduced to about 60%, and take warm after meals.

When prepared as a decoction (汤), decoct all herbs except E Jiao in water. Strain, then dissolve the E Jiao separately (烊化, yáng huà) in the hot strained liquid before drinking. Note that E Jiao should not be boiled directly with the other herbs, as this causes it to become sticky and adhere to the pot, reducing its effectiveness.

Common Modifications

How practitioners adapt Bu Fei E Jiao Tang for specific situations

Added
Bai Ji

6-10g, to astringe the Lungs and stop bleeding

Xian He Cao

10-15g, to stop bleeding and tonify

When Lung Yin deficiency has progressed to the point of significant hemoptysis, adding hemostatic herbs directly reinforces E Jiao's blood-stopping action and helps seal the damaged Lung vessels.

Educational content — always consult a qualified healthcare provider or TCM practitioner before using any herbal formula.

Contraindications

Situations where Bu Fei E Jiao Tang should not be used or requires extra caution

Avoid

Ma Dou Ling (Aristolochia fruit) in the classical formula contains aristolochic acid, which has documented nephrotoxicity and carcinogenicity. This ingredient has been banned in many countries and should NOT be used. Modern versions of this formula must substitute or omit Ma Dou Ling entirely.

Avoid

Lung deficiency without Heat (cold-type cough). This formula targets Yin deficiency with Heat and is inappropriate when the pattern is Lung Qi or Yang deficiency without Heat signs.

Avoid

Exterior Wind-Cold invasion (common cold with chills and clear nasal discharge). Using Yin-nourishing herbs during an acute exterior pattern may trap the pathogen inside.

Avoid

Profuse bloody sputum or active hemorrhage. This formula addresses mild blood-streaked sputum from Yin deficiency; significant bleeding requires more aggressive hemostatic treatment.

Caution

Spleen and Stomach deficiency with copious Phlegm-Dampness. The enriching, sticky nature of E Jiao (donkey-hide gelatin) can worsen Dampness and impair digestion in patients with significant Spleen weakness and phlegm accumulation.

Avoid

Patients with pre-existing kidney disease should exercise extra caution, particularly if the classical formula containing Ma Dou Ling is used, given the confirmed nephrotoxic potential of aristolochic acid.

Special Populations

Important considerations for pregnancy, breastfeeding, and pediatric use

Pregnancy

Use with significant caution during pregnancy. E Jiao (donkey-hide gelatin) is traditionally considered safe and even beneficial in pregnancy for nourishing Blood. However, the classical formula contains Ma Dou Ling (Aristolochia fruit), which contains aristolochic acid with documented nephrotoxicity and carcinogenicity. Ma Dou Ling is banned in many jurisdictions and must NOT be used during pregnancy (or at any other time). Niu Bang Zi (burdock seed) has a slippery, descending nature and is traditionally used with caution in pregnancy. Xing Ren (apricot kernel) contains amygdalin, and excessive doses could theoretically pose risks. If a modified version of this formula (without Ma Dou Ling) is considered during pregnancy, it should only be taken under strict supervision by a qualified practitioner.

Breastfeeding

The classical formula contains Ma Dou Ling (Aristolochia fruit), which contains aristolochic acid and is absolutely contraindicated during breastfeeding due to potential transfer of toxic metabolites through breast milk. If a modified version (without Ma Dou Ling) is used, the remaining ingredients (E Jiao, Niu Bang Zi, Xing Ren, Gan Cao, glutinous rice) are generally considered low risk during breastfeeding. However, Gan Cao (licorice) in significant doses may affect electrolyte balance and should be monitored. Xing Ren (apricot kernel) contains small amounts of amygdalin and should be kept within standard dosage. Consult a qualified practitioner before using any herbal formula while breastfeeding.

Children

This formula was originally designed specifically for pediatric use by Qian Yi, one of China's most celebrated children's doctors. The classical powder form called for small doses of 3–6 grams per serving, suitable for children. In modern decoction form, pediatric dosages are typically reduced to one-third to one-half of the adult dose, adjusted by age and body weight. For infants and very young children (under 3 years), expert guidance is essential. Children's digestive systems are delicate, and the rich, sticky nature of E Jiao may be difficult to digest; the dose of E Jiao should be reduced if digestive symptoms (poor appetite, loose stools) appear. CRITICAL: The classical ingredient Ma Dou Ling must NOT be used in children under any circumstances, as aristolochic acid nephrotoxicity has been documented in pediatric patients with particularly severe outcomes.

Drug Interactions

If you are taking pharmaceutical medications, be aware of these potential interactions with Bu Fei E Jiao Tang

Gan Cao (Glycyrrhiza/Licorice): Glycyrrhizin in licorice can cause pseudoaldosteronism (sodium retention, potassium loss, elevated blood pressure). It may interact with antihypertensive medications (reducing their effectiveness), diuretics (especially thiazides and loop diuretics, worsening hypokalemia), cardiac glycosides such as digoxin (hypokalemia increases digoxin toxicity), and corticosteroids (compounding mineralocorticoid effects). Patients on warfarin or other anticoagulants should be monitored, as licorice may affect drug metabolism.

E Jiao (Donkey-hide gelatin): Its rich, sticky nature may slow gastric emptying and potentially affect the absorption rate of concurrently taken oral medications. Patients taking oral drugs with narrow therapeutic windows should separate dosing times.

Ma Dou Ling (Aristolochia fruit) — if the classical formula is used: Aristolochic acid is nephrotoxic and hepatotoxic. It may dangerously compound the toxicity of any other nephrotoxic drugs (such as aminoglycosides, NSAIDs, cyclosporine, or cisplatin). This ingredient should be omitted entirely in modern practice.

Xing Ren (Apricot kernel): Contains amygdalin, which is metabolized to hydrogen cyanide. While standard doses are safe, caution is advised when combined with other cyanogenic foods or supplements.

Usage Guidance

Practical advice for getting the most out of Bu Fei E Jiao Tang

Best time to take

After meals (食后温服), taken warm, 2–3 times daily. The classical text specifies taking the formula after eating to protect the Stomach from the medicinal ingredients.

Typical duration

Typically prescribed for 1–4 weeks, reassessed regularly; chronic Yin deficiency conditions may require longer courses with periodic evaluation by a practitioner.

Dietary advice

Favor moistening, Yin-nourishing foods such as pears, white fungus (tremella), lily bulb, honey, sesame, and congee. These support the formula's goal of replenishing Lung fluids. Avoid spicy, fried, and excessively hot or drying foods (chili, pepper, roasted meats, alcohol, strong coffee) that can further deplete Lung Yin and aggravate internal Heat. Also avoid cold, raw foods and iced drinks, which can impair the Spleen's digestive function and reduce the formula's effectiveness, particularly the Earth-supporting action of the Gan Cao and glutinous rice components. Smoke exposure (including secondhand smoke) should be strictly avoided, as it directly irritates the Lungs and worsens the condition this formula treats.

Bu Fei E Jiao Tang originates from Xiao Er Yao Zheng Zhi Jue (小儿药证直诀) by Qian Yi (钱乙), compiled by Yan Xiaozhong (阎孝忠) Sòng dynasty, 1119 CE

Classical Texts

Key passages from the classical Chinese medical texts that first described Bu Fei E Jiao Tang and its clinical use

《小儿药证直诀》(Xiǎo Ér Yào Zhèng Zhí Jué) by Qian Yi, compiled by Yan Xiaozhong (Song Dynasty, 1119 CE):
Original indication: "小儿肺虚气粗喘促。"
"For children with Lung deficiency, coarse breathing, and urgent wheezing."

《医方考》(Yī Fāng Kǎo) by Wu Kun (Ming Dynasty):
"肺虚有火,嗽无津液,咳而哽气者,此方主之。燥者润之,今肺虚自燥,故润以阿胶、杏仁。金郁则泄之,今肺中郁火,故泄以兜铃、粘子。土者,金之母,虚者补其母,故入甘草、糯米,以补脾益胃。"
"This formula is indicated for Lung deficiency with fire, cough without fluids, and choking Qi. What is dry should be moistened; since the Lungs are deficient and thus dry, moisten them with E Jiao and Xing Ren. When Metal is constrained, it should be vented; since there is pent-up fire in the Lungs, vent it with Ma Dou Ling and Niu Bang Zi. Earth is the mother of Metal; for deficiency, tonify the mother, hence Gan Cao and glutinous rice to supplement the Spleen and Stomach."

《医方集解》(Yī Fāng Jí Jiě) by Wang Ang (Qing Dynasty):
"此手太阴药也。马兜铃清热降火,牛蒡子利膈消痰,杏仁润燥散风,降气止咳。阿胶清肺滋肾,益血补阴。气顺则不哽,液补则津生,火退而嗽宁矣。土为金母,故加甘草、粳米以益脾胃。"
"This is a formula for the Hand Taiyin [Lung] channel. Ma Dou Ling clears Heat and descends fire; Niu Bang Zi opens the diaphragm and dissolves Phlegm; Xing Ren moistens dryness, disperses Wind, descends Qi, and stops cough. E Jiao clears the Lungs and nourishes the Kidneys, enriches Blood and supplements Yin. When Qi flows smoothly there is no choking; when fluids are replenished, moisture is generated; when fire retreats, the cough subsides. Earth is the mother of Metal, hence Gan Cao and rice are added to benefit the Spleen and Stomach."

Historical Context

How Bu Fei E Jiao Tang evolved over the centuries — its origins, lineage, and place in the broader tradition of Chinese medicine

Bu Fei E Jiao Tang originates from the Xiǎo Ér Yào Zhèng Zhí Jué (《小儿药证直诀》, Craft of Medicinal Treatment for Childhood Disease Patterns), China's earliest surviving pediatric monograph. The formula was created by the celebrated Song Dynasty physician Qian Yi (钱乙, courtesy name Zhongyang 仲阳, c. 1032–1113 CE), who is revered as the "Sage of Pediatrics" (儿科之圣). The text was compiled posthumously by his student Yan Xiaozhong (阎孝忠, also known as Yan Jizhong 阎季忠) and published in 1119 CE. The formula originally appeared as "E Jiao San" (阿胶散) or "Bu Fei San" (补肺散) in powder form; the decoction form came to be known as Bu Fei E Jiao Tang.

Qian Yi's genius lay in adapting adult medical theory to the unique physiology of children, recognizing that "children's organs are delicate and tender, easily becoming deficient or excessive, easily turning cold or hot" (小儿脏腑柔弱,易虚易实,易寒易热). His formulas are characteristically mild and balanced. The Siku Quanshu Zongmu Tiyao (《四库全书总目提要》) praised his work as "the ancestor of pediatrics, from whose ideas later generations often achieved the power to bring back the dying." Besides this formula, Qian Yi also created enduring prescriptions such as Liu Wei Di Huang Wan, Dao Chi San, and Xie Bai San.

Important modern note: The classical formula contains Ma Dou Ling (马兜铃, Aristolochia fruit), which has been found to contain aristolochic acid, a substance with severe nephrotoxicity and proven carcinogenicity. Aristolochic acid has been classified as a Group 1 carcinogen by the WHO's International Agency for Research on Cancer. Many countries have banned Ma Dou Ling, and in 2003 Taiwan formally withdrew formulations containing aristolochic acid (including Bu Fei E Jiao San) from the market. In modern clinical practice, Ma Dou Ling is typically omitted or substituted with safer alternatives such as Sang Bai Pi (mulberry root bark) or Zhi Ke (bitter orange).