Formula

Qing Fei Pai Du Tang

清肺排毒汤

Also known as:

Clear the Lungs and Relieve Toxicity Formula

Properties

Exterior-releasing formulas · Slightly Warm

Key Ingredients

Ma Huang, Chai Hu

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

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About This Formula*

Traditional Chinese Medicine background and properties

Formula Description*

A modern composite formula developed during the COVID-19 pandemic to address respiratory infections caused by cold, dampness, and toxic pathogenic factors. It combines four classical formulas from the 2,000-year-old Shang Han Lun to open the Lungs, resolve dampness, clear heat, and expel toxins. Designed for use in acute febrile respiratory illness with cough, fatigue, and chest tightness.

Formula Category*

Main Actions*

  • Diffuses the Lungs and Expels Pathogenic Factors
  • Clears Heat and Resolves Toxicity
  • Transforms Dampness and Resolves Turbidity
  • Promotes Urination and Drains Dampness
  • Harmonizes the Shaoyang
  • Descends Lung Qi and Stops Cough
  • Strengthens the Spleen and transforms Phlegm-fluids

TCM Patterns*

In TCM, symptoms don't appear randomly — they cluster into recognizable patterns of disharmony that reveal what's out of balance in the body. Qing Fei Pai Du Tang is traditionally associated with these specific patterns.

The following describes this formula's classification within Traditional Chinese Medicine theory and is provided for educational purposes only.

Why Qing Fei Pai Du Tang addresses this pattern

This is the primary pattern targeted by the formula. In Cold-Damp Pestilence, an epidemic Cold-Damp pathogenic factor invades the Lung, obstructing its dispersing and descending functions. Dampness, being heavy and turbid, clogs the airways and generates phlegm, while Cold constricts the Lung Qi. The result is cough with thin white or frothy sputum, chest tightness, and labored breathing. Ma Huang and Gui Zhi release the exterior and warm the Lung to disperse Cold. Xi Xin penetrates deeply to transform Cold-Thin-Mucus. The Wu Ling San component (Fu Ling, Ze Xie, Zhu Ling, Bai Zhu, Gui Zhi) drains dampness from below while Huo Xiang aromatically transforms it from the Middle Burner. Zi Wan, Kuan Dong Hua, and She Gan dissolve phlegm and restore Lung Qi descent. This multi-layered approach clears dampness from the Lung, Spleen, and Bladder simultaneously.

A practitioner would look for one or more of these signs

Hypochondrial Pain That Is Worse On Coughing And Breathing

Persistent cough with thin white or frothy sputum

Chest Stiffness

Feeling of heaviness and oppression in the chest

Shortness Of Breath

Labored breathing, difficulty taking a full breath

Eye Fatigue

Pronounced fatigue and heavy limbs from dampness obstructing Qi flow

Fever

Low-grade or moderate fever that may be intermittent

Loss Of Appetite

Poor appetite from Spleen impairment by dampness

Nasal Congestion

Blocked nose from Cold obstructing Lung Qi

How It Addresses the Root Cause*

Qing Fei Pai Du Tang was designed to address the core disease mechanism of epidemic respiratory illness caused by what TCM classifies as a "cold-damp pestilential toxin" (寒湿疫毒). In this pattern, a virulent external pathogen invades the body through the nose and mouth, first lodging in the Lung system and the body's exterior defense layer. Because the pathogen carries both cold and damp qualities, it behaves differently from a simple Wind-Cold or Wind-Heat invasion: it is heavy, sticky, and difficult to expel, tending to linger and obstruct the normal flow of Qi and fluids.

The Lungs, which govern respiration and the downward movement of fluids, become congested and fail to properly diffuse Qi outward or direct water downward. This produces cough, wheezing, chest tightness, and a sense of heaviness. Simultaneously, the damp component impairs the Spleen's ability to transform and transport fluids, leading to internal accumulation of pathological moisture. This manifests as nausea, poor appetite, loose stools, a thick greasy tongue coating, and generalized fatigue. As the illness progresses, retained dampness can generate Heat through stagnation, creating a complex picture where cold, damp, and heat-toxin coexist at different levels of the body.

The pathogen does not stay at a single level. It may affect the Tai Yang (surface), Shao Yang (half-interior, half-exterior), and Tai Yin (interior Spleen-Lung) simultaneously, which is why the formula draws on prescriptions that address multiple stages of disease progression. The toxin also disrupts the San Jiao's (Triple Burner's) waterways, causing abnormal fluid metabolism throughout the body. This multi-system, multi-level disruption explains why a single classical formula would be insufficient, and why the formula's designer combined several classical prescriptions to address the entire pathological landscape at once.

Formula Properties*

Temperature

Slightly Warm

Taste Profile

Predominantly pungent and bitter with sweet undertones. The pungent quality opens and disperses (expelling pathogens from the surface and Lungs), the bitter quality clears Heat and dries Dampness, and the sweet quality tonifies the Spleen and harmonizes the other herbs.

Target Organs
Lungs Spleen Stomach Urinary Bladder San Jiao (Triple Burner)
Channels Entered
Lung Spleen Stomach Bladder San Jiao Gallbladder

Formula Origin

New formula created in January 2020 by Ge Youwen (葛又文), a special researcher at the China Academy of Chinese Medical Sciences, combining and modifying classical formulas from Zhang Zhongjing's Shang Han Za Bing Lun (伤寒杂病论). Officially recommended by the National Health Commission and National Administration of Traditional Chinese Medicine on February 6, 2020.

This is just partial information on the formula's TCM properties. More detailed information is available on the formula's dedicated page

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Product Details

Manufacturing, supplier, and product specifications

Product Type

Granules

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Supplier Information

Treasure of the East

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Ingredients in Qing Fei Pai Du Tang

Detailed information about each herb in Qing Fei Pai Du Tang and their roles

Kings
Deputies
Assistants
Envoys
Ma Huang
Ma Huang

Ephedra stem

Dosage: 9g

Temperature Warm
Taste Acrid / Pungent (辛 xīn), Bitter (苦 kǔ)
Organ Affinity Lungs, Urinary Bladder
Parts Used Stem (茎 jīng)
Role in Qing Fei Pai Du Tang

Opens the Lung Qi and releases the exterior, dispersing Cold and enabling the expulsion of pathogens through the skin. Restores the Lung's descending and dispersing functions, alleviating cough and wheezing. Serves as the shared core herb of two component formulas (Ma Xing Shi Gan Tang and She Gan Ma Huang Tang).

Chai Hu
Chai Hu

Bupleurum root

Dosage: 16g

Temperature Slightly Cool
Taste Acrid / Pungent (辛 xīn), Bitter (苦 kǔ)
Organ Affinity Liver, Gallbladder, Lungs
Parts Used Root (根 gēn)
Role in Qing Fei Pai Du Tang

Harmonizes the Shaoyang level and vents pathogenic factors that have penetrated beyond the exterior. Relieves alternating fever and chills, chest and hypochondriac fullness. At 16g, it is the highest-dosed herb in the formula, reflecting its critical role in preventing inward transmission of the pathogen.

Shi Gao
Shi Gao

Gypsum

Dosage: 15 - 30g

Temperature Cold
Taste Acrid / Pungent (辛 xīn), Sweet (甘 gān)
Organ Affinity Lungs, Stomach
Parts Used Mineral (矿物 kuàng wù)
Role in Qing Fei Pai Du Tang

Clears Lung heat and drains interior fire, counterbalancing the warming nature of Ma Huang and Gui Zhi. The flexible dosage (15-30g) allows adjustment based on the degree of fever: lower dose when no fever, higher dose for high fever.

Xing Ren
Xing Ren

Bitter apricot kernel

Dosage: 9g

Temperature Slightly Warm
Taste Bitter (苦 kǔ)
Organ Affinity Lungs, Large Intestine
Parts Used Seed (种子 zhǒng zǐ / 子 zǐ / 仁 rén)
Role in Qing Fei Pai Du Tang

Directs Lung Qi downward and stops cough. Together with Ma Huang, it forms a classical pair that both disperses and descends Lung Qi, restoring normal respiratory function.

Gui Zhi
Gui Zhi

Cinnamon twig

Dosage: 9g

Temperature Warm
Taste Acrid / Pungent (辛 xīn), Sweet (甘 gān)
Organ Affinity Heart, Lungs, Urinary Bladder
Parts Used Twig (枝 zhī)
Role in Qing Fei Pai Du Tang

Warms the channels, assists Ma Huang in releasing the exterior, and promotes the movement of Yang Qi. Also transforms Qi in the Bladder to assist water metabolism, linking the exterior-releasing strategy to the fluid-regulating Wu Ling San component.

Huang Qin
Huang Qin

Baical skullcap root

Dosage: 6g

Temperature Cold
Taste Bitter (苦 kǔ)
Organ Affinity Lungs, Gallbladder, Spleen, Large Intestine, Small Intestine, Heart, Stomach
Parts Used Root (根 gēn)
Role in Qing Fei Pai Du Tang

Clears heat from the Shaoyang and Lung levels. Pairs with Chai Hu in the Xiao Chai Hu Tang component to both vent and clear, preventing the pathogen from sinking deeper while addressing heat that has already formed.

Fu Ling
Fu Ling

Poria

Dosage: 15g

Temperature Neutral
Taste Sweet (甘 gān), Bland (淡 dàn)
Organ Affinity Heart, Lungs, Spleen, Kidneys
Parts Used Fungus / Mushroom (菌类 jūn lèi)
Role in Qing Fei Pai Du Tang

Strengthens the Spleen and promotes water metabolism through bland percolation. Part of the Wu Ling San component that resolves internal dampness accumulation and supports the Spleen's transport function.

Ze Xie
Ze Xie

Water plantain rhizome

Dosage: 9g

Temperature Cold
Taste Sweet (甘 gān), Bland (淡 dàn)
Organ Affinity Kidneys, Urinary Bladder
Parts Used Tuber (块茎 kuài jīng / 块根 kuài gēn)
Role in Qing Fei Pai Du Tang

Drains dampness and promotes urination, directing turbid fluids downward and out through the Bladder. A key herb in the Wu Ling San component for clearing accumulated fluid from the body.

Zhu Ling
Zhu Ling

Polyporus mushroom

Dosage: 9g

Temperature Neutral
Taste Sweet (甘 gān), Bland (淡 dàn)
Organ Affinity Kidneys, Urinary Bladder
Parts Used Fungus / Mushroom (菌类 jūn lèi)
Role in Qing Fei Pai Du Tang

Promotes urination and drains dampness, reinforcing the diuretic action of Ze Xie and Fu Ling in the Wu Ling San component. Helps clear pathological fluid accumulation that contributes to chest oppression and breathing difficulty.

Bai Zhu
Bai Zhu

White Atractylodes rhizome

Dosage: 9g

Temperature Warm
Taste Bitter (苦 kǔ), Sweet (甘 gān)
Organ Affinity Spleen, Stomach
Parts Used Rhizome (根茎 gēn jīng)
Role in Qing Fei Pai Du Tang

Tonifies the Spleen and dries dampness, strengthening the body's capacity to transform and transport fluids. Supports the Spleen as the source of Qi production, counteracting the fatigue and poor appetite that accompany the illness.

Ban Xia
Ban Xia

Pinellia rhizome

Dosage: 9g

Temperature Warm
Taste Acrid / Pungent (辛 xīn)
Organ Affinity Spleen, Stomach, Lungs
Parts Used Tuber (块茎 kuài jīng / 块根 kuài gēn)
Role in Qing Fei Pai Du Tang

Dries dampness and transforms phlegm, descends rebellious Stomach Qi to stop nausea. Part of the Xiao Chai Hu Tang component. The ginger-processed form reduces toxicity while enhancing its phlegm-resolving and anti-nausea effect.

Sheng Jiang
Sheng Jiang

Fresh ginger rhizome

Dosage: 9g

Temperature Slightly Warm
Taste Acrid / Pungent (辛 xīn)
Organ Affinity Lungs, Spleen, Stomach
Parts Used Rhizome (根茎 gēn jīng)
Role in Qing Fei Pai Du Tang

Warms the Middle Burner, disperses Cold, and harmonizes the Stomach. Assists Ma Huang and Gui Zhi in releasing the exterior while supporting digestion. Also helps moderate the cold nature of Shi Gao.

She Gan
She Gan

Blackberry lily rhizome

Dosage: 9g

Temperature Cold
Taste Bitter (苦 kǔ)
Organ Affinity Lungs
Parts Used Rhizome (根茎 gēn jīng)
Role in Qing Fei Pai Du Tang

Clears heat and resolves toxins in the throat, disperses phlegm accumulation. The key herb from the She Gan Ma Huang Tang component, specifically targeting throat congestion, swelling, and the sensation of phlegm blocking the airway.

Zi Wan
Zi Wan

Tatarian aster root

Dosage: 9g

Temperature Warm
Taste Acrid / Pungent (辛 xīn), Bitter (苦 kǔ)
Organ Affinity Lungs
Parts Used Root (根 gēn)
Role in Qing Fei Pai Du Tang

Moistens the Lungs and directs Qi downward to stop cough and dissolve phlegm. Part of the She Gan Ma Huang Tang component. Effective for both acute and chronic cough with difficult-to-expectorate phlegm.

Kuan Dong Hua
Kuan Dong Hua

Coltsfoot Flower

Dosage: 9g

Temperature Warm
Taste Acrid / Pungent (辛 xīn), Bitter (苦 kǔ)
Organ Affinity Lungs
Parts Used Flower bud (花蕾 huā lěi)
Role in Qing Fei Pai Du Tang

Moistens the Lungs, descends Qi, and stops cough. Works in concert with Zi Wan as a classical pair for cough relief, addressing both the acute spasmodic cough and the underlying phlegm congestion in the airways.

Xi Xin
Xi Xin

Wild Ginger

Dosage: 6g

Temperature Warm
Taste Acrid / Pungent (辛 xīn)
Organ Affinity Heart, Lungs, Kidneys
Parts Used Root (根 gēn)
Role in Qing Fei Pai Du Tang

Warms the Lungs and transforms Cold-Thin-Mucus (寒饮), opens the nasal passages, and disperses deeply lodged Cold. Critical for breaking through Cold-Damp obstruction in the Lungs. Part of the She Gan Ma Huang Tang component. Dosed at 6g to ensure adequate strength against the epidemic pathogen.

Shan Yao
Shan Yao

Chinese yam

Dosage: 12g

Temperature Neutral
Taste Sweet (甘 gān)
Organ Affinity Spleen, Lungs, Kidneys
Parts Used Rhizome (根茎 gēn jīng)
Role in Qing Fei Pai Du Tang

Tonifies Spleen and Lung Qi and nourishes Yin, providing gentle supplementation to protect the body's righteous Qi during an acute illness. Prevents the strongly dispersing and draining herbs from depleting the Spleen and Lung.

Zhi Shi
Zhi Shi

Immature Bitter Orange Fruit

Dosage: 6g

Temperature Slightly Cool
Taste Bitter (苦 kǔ), Acrid / Pungent (辛 xīn), Sour (酸 suān)
Organ Affinity Spleen, Stomach, Large Intestine
Parts Used Fruit (果 guǒ / 果实 guǒ shí)
Role in Qing Fei Pai Du Tang

Breaks Qi stagnation and reduces distension, directing Qi downward. Helps relieve chest and abdominal fullness caused by the accumulation of dampness and phlegm. Ensures smooth Qi flow so that the other herbs can circulate effectively.

Chen Pi
Chen Pi

Tangerine peel

Dosage: 6g

Temperature Warm
Taste Acrid / Pungent (辛 xīn), Bitter (苦 kǔ)
Organ Affinity Lungs, Spleen
Parts Used Peel / Rind (皮 pí / 果皮 guǒ pí)
Role in Qing Fei Pai Du Tang

Regulates Qi and dries dampness, harmonizes the Middle Burner. Assists the Spleen in transforming dampness and prevents the rich, cloying herbs from causing Qi stagnation in the digestive system.

Huo Xiang
Huo Xiang

Patchouli herb

Dosage: 9g

Temperature Slightly Warm
Taste Acrid / Pungent (辛 xīn), Aromatic (芳香 fāng xiāng)
Organ Affinity Spleen, Stomach, Lungs
Parts Used Whole plant / Aerial parts (全草 quán cǎo)
Role in Qing Fei Pai Du Tang

Aromatically transforms dampness and turbidity, harmonizes the Middle Burner, and stops nausea. Addresses the core damp-turbid quality of the epidemic pathogen. Its aromatic nature penetrates through turbid dampness that bland diuretics alone cannot resolve.

Gan Cao
Gan Cao

Licorice root

Dosage: 6g

Temperature Neutral
Taste Sweet (甘 gān)
Organ Affinity Heart, Lungs, Spleen, Stomach
Parts Used Root (根 gēn)
Role in Qing Fei Pai Du Tang

Harmonizes all the herbs in the formula and tonifies Spleen Qi. Moderates the harsh or strongly moving properties of Ma Huang, Shi Gao, and the diuretic herbs, protecting the Stomach. Serves as the envoy that unifies four classical formulas into one cohesive prescription.

Modern Research (5 studies)

  • Association between Use of Qingfei Paidu Tang and Mortality in Hospitalized Patients with COVID-19: A National Retrospective Registry Study (2021)
  • Effectiveness and Safety Research of Qingfei Paidu (QFPD) in Treatment of COVID-19: An Up-to-Date Systematic Review and Meta-Analysis (2022)
See all research on the formula page

Usage & Safety

How to use this formula and important safety information

Important Medical Disclaimer

The information provided here is for educational purposes only and is not intended as medical advice or to replace consultation with a qualified healthcare professional. This formula is a dietary supplement and has not been evaluated by the FDA. It is not intended to diagnose, treat, cure, or prevent any disease.

Always consult with a qualified healthcare provider, particularly if you are pregnant, nursing, have a medical condition, or are taking other medications. Discontinue use and consult your healthcare provider if you experience any adverse reactions.

Recommended Dosage

Instructions for safe storage and consumption

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Best Time to Take

Twice daily (morning and evening), 40 minutes after meals, served warm. Optionally follow each dose with a small bowl of warm rice porridge.

Typical Duration

Acute use: 3 days per course (one dose daily). A second course may follow with possible modifications based on the patient's response. Not intended for long-term use.

Dietary Advice

While taking Qing Fei Pai Du Tang, avoid cold and raw foods (salads, ice cream, cold drinks, raw fruit), greasy and fried foods, dairy products, and overly sweet or rich foods. These can generate more Dampness and Phlegm internally, counteracting the formula's drying and transforming actions. Avoid alcohol, strong tea, and coffee, which can interfere with the herbs' actions. Favor warm, easily digestible foods: plain rice porridge (congee), steamed vegetables, light soups. The official dosing instructions specifically recommend drinking a small bowl of warm rice porridge (大米汤) after taking each dose to support the Stomach Qi and help the formula's ingredients distribute throughout the body. Avoid sour and astringent foods (vinegar, citrus, pickled foods) during treatment, as these can counteract the dispersing actions of the exterior-releasing herbs.

Modern Usage*

Qing Fei Pai Du Tang is designed with a unique blend of traditional Chinese medicinal formulas, drawing inspiration from classics like Ma Xing Shi Gan Decoction, She Gan Ma Huang Decoction, Xiao Chai Hu Tang, and Wu Ling San.

Original Composition: Qing Fei Pai Du Tang traditionally includes Ma Huang (9 g), Zhi Gan Cao (6 g), Xing Ren (9 g), Sheng Shi Gao (15–30 g), Gui Zhi (9 g), Ze Xie (9 g), Zhu Ling (9 g), Bai Zhu (9 g), Fu Ling (15 g), Chai Hu (16 g), Huang Qin (6 g), Jiang Ban Xia (9 g), Sheng Jiang (9 g), Zi Wan (9 g), Kuan Dong Hua (9 g), Shegan (9 g), Xi Xin (6 g), Shan Yao (12 g), Zhi Shi (6 g), Chen Pi (6 g), and Huo Xiang (9 g).

Due to the ban on Ma Huang and Xi Xin by the US FDA, Dr. Boli Zhang, Honorary President of the China Academy of Chinese Medical Sciences, recommends substituting Ma Huang with Xiang Ru and Xi Xin with Xin Yi.

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Special Populations

Pregnancy

Contraindicated. Chinese health authorities explicitly state that pregnant women are not within the recommended user population for Qing Fei Pai Du Tang. The formula contains several herbs with known pregnancy risks: - Ma Huang (Ephedra): contains sympathomimetic alkaloids that can raise blood pressure and heart rate, and may stimulate uterine contractions. - Xi Xin (Asarum): classified as a restricted or banned substance in some jurisdictions due to aristolochic acid content, and traditionally considered incompatible with pregnancy. - Jiang Ban Xia (prepared Pinellia): despite ginger processing to reduce toxicity, Pinellia is classically listed among pregnancy-cautioned herbs. - Zhi Shi (Immature Bitter Orange): has Qi-moving and downward-directing properties that may theoretically affect the uterus. Pregnant women who develop respiratory illness should consult their healthcare provider for individually tailored treatment.

Breastfeeding

Caution advised. Chinese health guidelines recommend that breastfeeding women use this formula only under the guidance of a qualified physician. While specific data on transfer of the formula's active compounds through breast milk are limited, several ingredients raise concerns: - Ma Huang (Ephedra): ephedrine alkaloids are known to pass into breast milk and may cause irritability, sleep disturbance, or tachycardia in the nursing infant. - Xi Xin (Asarum): contains potentially toxic aristolochic acid derivatives, and its safety profile during lactation is unknown. - Jiang Ban Xia (Pinellia): while processed to reduce toxicity, its effects on breastfed infants have not been studied. If treatment is necessary, a practitioner may consider modifications or substitutions. Short-term use (one course of 3 days) under medical supervision is more acceptable than prolonged use.

Pediatric Use

Official Chinese guidelines exclude children under 6 years of age from the recommended population for Qing Fei Pai Du Tang. For children aged 6 and above, the formula should only be used under the direct supervision of a qualified TCM practitioner, with dosages adjusted proportionally based on age and body weight. A common guideline is: - Ages 6-9: approximately 1/3 to 1/2 of the adult dose - Ages 10-14: approximately 1/2 to 2/3 of the adult dose - Ages 15+: may approach adult dosing depending on body size Special attention should be paid to Ma Huang (Ephedra), which can cause restlessness, insomnia, and elevated heart rate in children, and Xi Xin (Asarum), which is restricted in several jurisdictions due to safety concerns. If the child shows any adverse reactions such as vomiting, diarrhea, palpitations, or skin rash, the formula must be discontinued immediately. For very young children with respiratory illness, practitioners typically prefer gentler pediatric-specific formulas.

Cautions & Warnings

Although this formula is typically safe for most individuals, it may cause side effects in some people. Pregnant women, nursing mothers, postpartum women, and those with liver disease should use the formula with caution.

As with any Chinese herbal remedy, it is advisable to seek guidance from a qualified TCM practitioner before beginning treatment.