Yu Nu Jian

Jade Woman Decoction · 玉女煎

A classical formula designed to cool excessive Stomach Heat while nourishing Kidney Yin. It is commonly used for toothache, bleeding gums, dry mouth, and intense thirst caused by a combination of internal heat and fluid depletion. It is also frequently applied to conditions like diabetes and oral inflammation when the same underlying pattern is present.

Origin Jǐng Yuè Quán Shū (景岳全书, Collected Treatises of Jing Yue), Volume 51 — Míng dynasty, circa 1624 CE
Composition 5 herbs
Shi Gao
King
Shi Gao
Shu Di Huang
Deputy
Shu Di Huang
Zhi Mu
Assistant
Zhi Mu
Mai Dong
Assistant
Mai Dong
Niu Xi
Envoy
Niu Xi
Explore composition

Educational content Consult qualified TCM practitioners for diagnosis and treatment

Patterns Addressed

In TCM, symptoms don't appear randomly — they cluster into recognizable patterns of disharmony that reveal what's out of balance in the body. Yu Nu Jian is designed to correct these specific patterns.

Why Yu Nu Jian addresses this pattern

When Stomach Fire blazes excessively, Heat travels upward along the Yangming channel into the face, head, and gums. This causes toothache, headache, bleeding gums, bad breath, intense thirst, and a preference for cold drinks. However, what distinguishes the Yu Nu Jian pattern from simple Stomach Fire (as treated by Qing Wei San) is that there is a simultaneous deficiency of Kidney Yin. The Kidneys govern the bones, and teeth are considered extensions of the bones. When Kidney Yin fails to nourish the teeth from below while Stomach Fire scorches them from above, the teeth become loose and the gums bleed readily. Shi Gao and Zhi Mu directly drain the Stomach Fire while Shu Di Huang and Mai Dong replenish the depleted Yin, and Niu Xi pulls the Heat downward and away from the head.

A practitioner would look for one or more of these signs

Toothache

Severe, often in the upper teeth along the Yangming channel

Bleeding Gums

Gum bleeding with red, swollen gingiva

Headaches

Heat-type headache, especially frontal

Thirst

Intense thirst with desire for cold drinks

Bad Breath

Foul mouth odor from Stomach Heat

Commonly Prescribed For

These conditions can arise from the patterns above. A practitioner would consider Yu Nu Jian when these conditions are specifically caused by those patterns — not for all cases of these conditions.

TCM Interpretation

In TCM, the health of the gums and teeth depends on the balance between the Stomach and the Kidneys. The Stomach channel runs through the upper and lower gums, so Stomach Fire directly inflames the gingival tissue, causing redness, swelling, and bleeding. Meanwhile, the Kidneys govern the bones, and teeth are considered extensions of the skeletal system. When Kidney Yin is depleted, the bones and teeth lose their nourishment, leading to loosening, recession, and deterioration. Chronic periodontitis thus reflects both an excess (Stomach Fire attacking the gums) and a deficiency (Kidney Yin failing to sustain the teeth and bone).

Why Yu Nu Jian Helps

Yu Nu Jian directly addresses both sides of this problem. Shi Gao powerfully clears the Stomach Fire that inflames the gums, while Zhi Mu assists this action and adds a moistening quality. Shu Di Huang nourishes Kidney Yin to support the bone and tooth structure from within. Mai Dong generates fluids that soothe dry, inflamed oral tissues. Niu Xi directs Blood and Heat downward, reducing the upward flooding of Heat into the gums, which helps control bleeding. Clinical studies have shown that Yu Nu Jian combined with conventional periodontal treatment improves gum bleeding indices, plaque levels, and pocket depth more effectively than conventional treatment alone.

Also commonly used for

Gingivitis

Especially with red, swollen, bleeding gums from Stomach Heat

Glossitis

Tongue inflammation with redness and pain

Corneal Ulcers

Mouth sores from Stomach Heat and Yin deficiency

Lichen Planus

Erosive type with Heat and Yin deficiency pattern

Trigeminal Neuralgia

Facial pain along the Yangming distribution

Epistaxis

Nosebleeds from upward-flaring Stomach Heat

Acne

When driven by Stomach Heat and Yin deficiency

Gastroesophageal Reflux Disease

With prominent Heat signs

Hyperthyroidism

When presenting with Heat signs, thirst, and weight loss

What This Formula Does

Every TCM formula has a specific set of actions — here's what Yu Nu Jian does in the body, explained in both everyday and TCM terms

Therapeutic focus

In practical terms, Yu Nu Jian is primarily used to support these areas of health:

TCM Actions

In TCM terminology, these are the specific therapeutic actions that Yu Nu Jian performs to restore balance in the body:

How It Addresses the Root Cause

TCM doesn't just suppress symptoms — it aims to resolve the underlying imbalance. Here's how Yu Nu Jian works at the root level.

Yu Nu Tang addresses a dual imbalance where two organ systems have gone wrong simultaneously: the Stomach has too much Heat, and the Kidneys lack sufficient Yin (nourishing fluids). In TCM theory, this is described as "Shaoyin insufficiency with Yangming excess" (少阴不足,阳明有余), meaning the Kidney system is depleted while the Stomach system is overactive.

Here is how the disease develops: Kidney Yin acts as the body's deep reservoir of cooling, moistening fluids. When this reservoir runs low, it can no longer keep the Stomach's natural warmth in check. The Stomach, part of the Yangming system, tends to run hot by nature because of its vigorous digestive function. Without adequate Kidney Yin to counterbalance it, Stomach Heat flares upward. The Yangming Stomach channel travels up through the face and into the gums, so when its Heat rises unchecked, it attacks the head and mouth, causing headaches, toothache, bleeding and swollen gums, and dry thirst. The teeth themselves are considered the "surplus of the bones" in TCM, and bones are governed by the Kidneys. So when Kidney Yin is depleted, the teeth lose their nourishment and become loose. The Heat also scorches the Blood vessels, leading to gum bleeding or nosebleeds.

The key diagnostic clue is a pulse that feels large and surging on the surface but weak when pressed firmly. This reflects the combination: the floating, forceful quality shows the Stomach Heat flaring outward, while the weak deep quality reveals the underlying Yin depletion beneath. The formula works because it simultaneously quenches the Stomach Fire above and replenishes the Kidney Water below, addressing both the branch symptom (excess Heat) and the root cause (Yin deficiency).

Formula Properties

Every formula has an inherent temperature, taste, and affinity for specific organs — these properties determine how it interacts with the body

Overall Temperature

Cold

Taste Profile

Predominantly sweet and bitter with a pungent note from Shi Gao. Sweet to nourish Yin and generate fluids, bitter to clear Heat and direct Fire downward, pungent to disperse stagnant Heat from the Stomach.

Channels Entered

Stomach Kidney Lung

Ingredients

5 herbs

The herbs that make up Yu Nu Jian, organized by their role in the prescription

King — Main ingredient driving the formula
Deputy — Assists and enhances the King
Assistant — Supports or moderates other herbs
Envoy — Directs the formula to its target
King — Main ingredient driving the formula
Shi Gao

Shi Gao

Gypsum

Dosage 15 - 30g
Temperature Cold
Taste Acrid / Pungent (辛 xīn), Sweet (甘 gān)
Organ Affinity Lungs, Stomach
Preparation Crush and decoct first (先煎) for 15-20 minutes

Role in Yu Nu Jian

Clears intense Heat from the Stomach (Yangming channel). Its acrid, sweet, and very cold nature directly drains excess Stomach Fire, the root cause of the toothache, headache, and feverish agitation in this pattern.
Deputy — Assists and enhances the King
Shu Di Huang

Shu Di Huang

Prepared Rehmannia root

Dosage 9 - 30g
Temperature Slightly Warm
Taste Sweet (甘 gān)
Organ Affinity Liver, Kidneys

Role in Yu Nu Jian

Nourishes Kidney Yin and replenishes essence and Blood. It addresses the underlying Yin deficiency (the 'insufficiency of the lesser Yin') that allows Stomach Fire to blaze unchecked. Paired with Shi Gao, it ensures that both excess and deficiency are treated simultaneously.
Assistants — Supports or moderates other herbs
Zhi Mu

Zhi Mu

Anemarrhena rhizome

Dosage 4.5 - 5g
Temperature Cold
Taste Bitter (苦 kǔ), Sweet (甘 gān)
Organ Affinity Lungs, Stomach, Kidneys

Role in Yu Nu Jian

Assists Shi Gao in clearing Stomach Heat while also nourishing Yin with its moistening quality. Its bitter and cold nature clears Heat from both the Qi level and the lower Burner, bridging the actions of the King and Deputy herbs.
Mai Dong

Mai Dong

Ophiopogon root

Dosage 6g
Temperature Slightly Cool
Taste Sweet (甘 gān), Bitter (苦 kǔ)
Organ Affinity Heart, Lungs, Stomach

Role in Yu Nu Jian

Nourishes Yin in the Stomach and Lungs, generates fluids, and clears Heat from the Heart to relieve irritability. It complements Shu Di Huang's Kidney-nourishing action by moistening the upper and middle Burners.
Envoy — Directs the formula to its target
Niu Xi

Niu Xi

Ox Knee Root

Dosage 4.5 - 5g
Temperature Neutral
Taste Bitter (苦 kǔ), Sour (酸 suān), Sweet (甘 gān)
Organ Affinity Liver, Kidneys

Role in Yu Nu Jian

Directs Heat and Blood downward, pulling the flaring Stomach Fire away from the head and gums. This downward-directing action helps stop gum bleeding and relieve toothache. It also nourishes the Liver and Kidneys, supporting the formula's Yin-tonifying strategy.

Why This Combination Works

How the herbs in Yu Nu Jian complement each other

Overall strategy

Yu Nu Jian addresses a condition where Stomach Heat is blazing upward while Kidney Yin is depleted below. The prescription simultaneously clears the excess Fire from the Yangming (Stomach) channel and replenishes the deficient Water of the Shaoyin (Kidney), tackling both the root and the branch of the disease.

King herbs

Shi Gao (Gypsum) is the King herb. Its acrid, sweet, and intensely cold nature enters the Yangming channel directly, making it the most powerful herb in the formula for draining Stomach Fire. It is responsible for relieving the acute symptoms of toothache, headache, feverish agitation, and thirst that arise when Stomach Heat flares upward along the channel into the face and head.

Deputy herbs

Shu Di Huang (Prepared Rehmannia) serves as the Deputy. While the King herb attacks the excess above, the Deputy nourishes the deficiency below. Shu Di Huang's sweet, slightly warm nature enriches Kidney Yin and replenishes Blood and essence. This pairing of a strongly cold, Heat-clearing herb with a rich Yin-nourishing herb is the strategic heart of the formula: it clears Fire and strengthens Water at the same time, addressing both the excess and the deficiency.

Assistant herbs

Zhi Mu (Anemarrhena) is a reinforcing assistant that bridges both therapeutic arms. Its bitter, cold, and moistening qualities help Shi Gao clear Stomach Heat while also nourishing Yin from below, supporting Shu Di Huang. Mai Dong (Ophiopogon) is another reinforcing assistant that generates fluids, moistens the Stomach, and clears Heart Heat to relieve irritability. It focuses its Yin-nourishing action on the upper and middle Burners, complementing Shu Di Huang's action on the Kidneys.

Envoy herbs

Niu Xi (Achyranthes) acts as the Envoy. Its key role is to direct Blood and Heat downward, pulling the raging upward-flaring Fire back down away from the head, gums, and teeth. This downward guidance is essential for stopping gum bleeding and relieving the head and tooth pain. As a secondary benefit, Niu Xi also tonifies the Liver and Kidneys, adding to the formula's Yin-supporting foundation.

Notable synergies

The Shi Gao and Shu Di Huang pairing is the defining synergy of this formula. Shi Gao clears excess Heat from the Stomach while Shu Di Huang nourishes deficient Yin in the Kidneys. Together they restore the balance between the Yangming (Stomach) and Shaoyin (Kidney) systems. The Zhi Mu and Mai Dong pairing echoes this strategy at a smaller scale: Zhi Mu leans toward Heat-clearing while Mai Dong leans toward fluid generation, and together they reinforce both therapeutic directions.

How to Prepare

Traditional preparation instructions for Yu Nu Jian

Combine all herbs with approximately 300 ml of water (one and a half cups in classical measure). Shi Gao (Gypsum) should be crushed and decocted first for 15 to 20 minutes before adding the remaining herbs. Then bring to a boil and simmer until approximately 70% of the liquid remains. Strain and take warm or slightly cool. Typically taken as one dose per day, divided into two servings.

Common Modifications

How practitioners adapt Yu Nu Jian for specific situations

Added
Zhi Zi

Shan Zhi Zi (Gardenia), 6-9g, to clear Heat from all three Burners and drain Fire downward through urination

Di Gu Pi

Di Gu Pi (Lycium Root Bark), 9-12g, to clear deficiency Heat and cool the Blood

When Fire is particularly intense, adding Zhi Zi and Di Gu Pi strengthens the Heat-clearing action from multiple angles. Zhi Zi drains Fire via the urine while Di Gu Pi cools deficiency Heat, together preventing the Fire from overwhelming the formula's baseline clearing capacity.

Educational content — always consult a qualified healthcare provider or TCM practitioner before using any herbal formula.

Contraindications

Situations where Yu Nu Jian should not be used or requires extra caution

Avoid

Spleen deficiency with loose stools or diarrhea. The formula's cold nature and Yin-nourishing herbs (especially Shu Di Huang, Zhi Mu, and Mai Dong) can further impair a weak Spleen's ability to transform fluids, worsening diarrhea.

Avoid

True Yang deficiency Cold patterns without any signs of Heat. This formula clears Heat and nourishes Yin, so it would further deplete already insufficient Yang Qi.

Caution

Toothache or gum bleeding caused purely by excess Stomach Fire without underlying Yin deficiency. A purely clearing formula such as Qing Wei San would be more appropriate.

Caution

Patients with poor appetite, bloating, or heavy sensation in the limbs from Dampness or Phlegm accumulation. The rich, cloying nature of Shu Di Huang can worsen these symptoms.

Avoid

Pregnancy. Niu Xi (Achyranthes root) has blood-moving and downward-directing properties and is traditionally classified as contraindicated during pregnancy.

Special Populations

Important considerations for pregnancy, breastfeeding, and pediatric use

Pregnancy

Contraindicated during pregnancy. Niu Xi (Achyranthes, 牛膝) is the primary concern. It has traditionally been classified as a pregnancy-prohibited herb due to its blood-moving and strongly downward-directing properties. Classical texts including the Shen Nong Ben Cao Jing note its ability to 'cause miscarriage' (堕胎). Modern pharmacological research confirms that Niu Xi can stimulate uterine smooth muscle contractions and has anti-early-pregnancy effects. Additionally, the overall cold nature of this formula (driven by Shi Gao and Zhi Mu) is generally considered unfavorable during pregnancy. Pregnant women experiencing similar symptoms of Stomach Heat with Yin deficiency should seek alternative formulas under professional guidance.

Breastfeeding

Use with caution during breastfeeding. Niu Xi (Achyranthes) has blood-moving properties, and its effects on breast milk transfer are not well studied. Shi Gao and Zhi Mu are cold in nature, and prolonged use could theoretically affect the nursing mother's digestive function and milk quality if taken in excessive doses. While no specific adverse effects on breastfed infants have been documented, the formula's overall cold and Yin-nourishing nature may not be ideal for postpartum women, who often present with Qi and Blood deficiency. Short-term use under professional supervision is advisable if the clinical presentation clearly matches the formula's indications.

Children

Yu Nu Tang can be used in children when the clinical pattern clearly matches (Stomach Heat with Yin deficiency), but dosages must be significantly reduced according to age and body weight. A common approach is to use one-third to one-half of the adult dose for children aged 6 to 12, and one-quarter for those under 6, though precise dosing should be determined by a qualified practitioner. Because the formula is cold in nature and contains rich Yin-nourishing herbs, it should be used for shorter durations in children to protect their inherently delicate Spleen and Stomach function. If digestive symptoms such as loose stools or reduced appetite appear, the formula should be discontinued. Not recommended for infants without direct professional supervision.

Drug Interactions

If you are taking pharmaceutical medications, be aware of these potential interactions with Yu Nu Jian

Niu Xi (Achyranthes) and anticoagulant/antiplatelet medications: Niu Xi has documented blood-moving and anticoagulant properties. It may increase the risk of bleeding when used alongside warfarin, heparin, aspirin, or clopidogrel. Patients on blood-thinning medications should be monitored closely.

Shi Gao (Gypsum) and calcium-containing medications: Shi Gao is primarily calcium sulfate. Taking it alongside calcium supplements or medications that affect calcium metabolism could potentially alter calcium levels, though clinically significant interactions are uncommon at standard decoction doses.

Zhi Mu (Anemarrhena) and hypoglycemic drugs: Zhi Mu has demonstrated blood-sugar-lowering effects in pharmacological studies. When Yu Nu Tang is used for diabetic patients (a common modern application), concurrent use with insulin or oral hypoglycemics such as metformin may require closer blood glucose monitoring to avoid hypoglycemia.

General note on mineral absorption: The calcium content from Shi Gao may theoretically reduce absorption of certain antibiotics (tetracyclines, fluoroquinolones) and thyroid medications (levothyroxine) if taken simultaneously. Spacing doses by at least two hours is prudent.

Usage Guidance

Practical advice for getting the most out of Yu Nu Jian

Best time to take

Between meals (about 1 hour after eating), twice daily. The original text notes it may be taken warm or cool, depending on the severity of Heat symptoms. Those with prominent Heat and thirst may benefit from taking it slightly cooled.

Typical duration

Short-term use: typically 5 to 14 days for acute presentations such as severe toothache or gum inflammation, then reassessed. May be extended to 2 to 4 weeks for chronic conditions like diabetes-related thirst with appropriate monitoring.

Dietary advice

Avoid spicy, fried, and greasy foods (such as chili peppers, fried meats, and rich curries) while taking this formula, as these can generate further Stomach Heat and undermine the formula's cooling action. Also avoid alcohol and strong coffee, which tend to produce Heat and dry fluids. Cold and raw foods should be consumed in moderation. While the formula itself is cold in nature, excessively cold or icy foods can impair digestion and reduce the Spleen's ability to absorb the formula's benefits. Favor cooling, moistening foods such as pears, watermelon (in moderate amounts), mung beans, tofu, cucumber, lotus root, and congee. These support the formula's Yin-nourishing and Heat-clearing effects.

Yu Nu Jian originates from Jǐng Yuè Quán Shū (景岳全书, Collected Treatises of Jing Yue), Volume 51 Míng dynasty, circa 1624 CE

Classical Texts

Key passages from the classical Chinese medical texts that first described Yu Nu Jian and its clinical use

Zhang Jingyue, Jing Yue Quan Shu (《景岳全书》), Volume 51, Xin Fang Ba Zhen (New Formulas, Eight Arrays):

「治水亏火盛,六脉浮洪滑大,少阴不足,阳明有余,烦热干渴,头痛牙疼,失血等证。若大便溏泄者,乃非所宜。」

Translation: Treats water depletion with Fire excess, where all six pulse positions are floating, surging, slippery, and large. The Shaoyin (Kidneys) are insufficient and the Yangming (Stomach) is in excess, with irritable Heat, dry thirst, headache, toothache, and bleeding disorders. If there is loose stools and diarrhea, this formula is not appropriate.


Zhang Bingcheng, Cheng Fang Bian Du (《成方便读》):

「人之真阴充足,水火均平,决不致有火盛之病。若肺肾真阴不足,不能濡润于胃,胃汁干枯,一受火邪,则燎原之势而为似白虎之证矣。」

Translation: When a person's true Yin is sufficient and water and fire are balanced, there will never be illness from Fire excess. But if the true Yin of the Lungs and Kidneys is insufficient and unable to moisten the Stomach, the Stomach fluids dry up, and once affected by Fire pathogen, it spreads like wildfire, presenting as a pattern resembling Bai Hu (White Tiger) syndrome.

Historical Context

How Yu Nu Jian evolved over the centuries — its origins, lineage, and place in the broader tradition of Chinese medicine

Yu Nu Tang was created by Zhang Jingyue (张景岳, 1563–1640), one of the most influential physicians of the Ming Dynasty. Zhang was a towering figure who founded the "Warm Supplementation" (温补) school of thought and authored the monumental Jing Yue Quan Shu (Complete Works of Jingyue). Despite being known primarily as a warm-supplementation advocate, Zhang understood that certain conditions require clearing Heat, and Yu Nu Tang is a masterful example of this flexibility. The formula appears in Volume 51 under his innovative "Xin Fang Ba Zhen" (New Formulas, Eight Arrays) section, where he organized prescriptions using military metaphors inspired by the art of war.

The name "Yu Nu" (Jade Maiden) has poetic origins tied to Daoist culture, which deeply influenced Zhang Jingyue. In Daoist tradition, the Kidneys are sometimes referred to as the "Jade Maiden," so the formula's name alludes to its Yin-nourishing action. An alternative explanation points to Shi Gao (Gypsum), the chief herb, whose pure white, jade-like mineral appearance evokes the image of a maiden. Later physicians significantly modified the formula. Wu Jutong (吴鞠通), in his Wen Bing Tiao Bian (Systematic Differentiation of Warm Diseases), adapted it by replacing Shu Di Huang with Sheng Di Huang and substituting Niu Xi with Xuan Shen, redirecting the formula toward treating warm-febrile diseases where Heat has entered both the Qi and Blood levels simultaneously. Tang Zonghai (唐宗海), in his Xue Zheng Lun (Treatise on Blood Patterns), praised Yu Nu Tang for treating coughing blood related to Yangming channel Heat.

Modern Research

2 published studies investigating the pharmacological effects or clinical outcomes of Yu Nu Jian

1

Meta-analysis: Efficacy and Safety of Modified Yunu-Jian in Patients with Periodontitis (2021)

Pan Y, Li Q, et al. Evidence-Based Complementary and Alternative Medicine, 2021, Volume 2021, Article ID 5540214.

This meta-analysis reviewed 13 randomized controlled trials involving 1,179 participants with periodontitis. The results showed that modified Yu Nu Jian combined with conventional Western treatment significantly improved the overall clinical effective rate compared to Western treatment alone. Key periodontal indexes (gingival index, sulcus bleeding index, plaque index, and probing depth) all showed statistically significant improvement. No serious adverse reactions were reported in the treatment groups. The authors noted, however, that the methodological quality of the included trials was generally low and called for further well-designed studies.

PubMed
2

RCT: Adjunctive Use of Modified Yunu-Jian in Non-Surgical Treatment of Male Smokers with Chronic Periodontitis (2016)

Zee KY, Chan PS, Ho JCS, Lai SML, Corbet EF. Chinese Medicine, 2016, 11:40.

This randomized, double-blind, placebo-controlled clinical trial evaluated modified Yu Nu Jian as an adjunct to non-surgical periodontal treatment in 25 male smokers with chronic periodontitis who displayed the TCM pattern of Stomach Heat and Kidney Yin deficiency. After 12 months, the treatment group showed significantly preserved radiographic alveolar bone density at study sites compared to controls. The treatment group also showed marked improvement in their TCM syndrome assessment, with far fewer participants displaying persistent Stomach Heat and Kidney Yin deficiency at follow-up. All participants tolerated the formula well.

PubMed

Research on TCM formulas is growing but still limited by Western clinical trial standards. These studies provide emerging evidence and should be considered alongside practitioner expertise.