Practitioner-reviewed Updated Jun 2026 1 clinical study

Diabetic Retinopathy

消渴内障 · xiāo kě nèi zhàng

Diabetic retinopathy in TCM is understood as a progression through distinct patterns - Yin deficiency, Qi and Yin depletion, and blood stasis - and treatment shifts with each stage. Early, consistent care can help stabilize the retinal vessels and reduce the frequency of invasive procedures.

4 Patterns
11 Herbs
5 Formulas
12 Acupoints
About this page · what it is and isn't

What this is. A plain-English synthesis of how classical TCM and modern clinical research describe diabetic retinopathy. Patterns and herbs come from canonical TCM sources; clinical claims are cited in the Evidence section.

What it isn't. A diagnosis. Me&Qi is an editorial team, not a licensed clinic. The pattern quiz is a thinking tool — pulse and tongue still need a person in the room. Anything in the Safety section should send you to a doctor, not a herb.

Last reviewed Jun 2026.

Educational content about Traditional Chinese Medicine — not medical advice. See a qualified practitioner for diagnosis and treatment.

Diabetic retinopathy is one of the conditions where Traditional Chinese Medicine offers a fundamentally different lens. Rather than seeing it as a single disease driven only by high blood sugar, TCM identifies several distinct patterns - from Yin deficiency with Empty-Heat to deep Blood Stagnation - that each demand a different treatment strategy. The same retinal bleeding can be caused by heat scorching fragile vessels in one person and by Qi failing to hold blood in another. This page walks you through those patterns so you can understand what may be happening beneath the surface and how TCM approaches it.

How TCM understands diabetic retinopathy

TCM views diabetic retinopathy not as an isolated eye problem but as a late-stage consequence of Xiao Ke, the broader wasting-and-thirsting disorder that corresponds to diabetes. The root lies in years of high blood sugar consuming the body's Yin - the cooling, moistening, nourishing foundation - especially in the Kidneys and Liver. When Yin is too weak to anchor the body's Yang, empty heat rises along the channels to the eyes, where it scorches the delicate retinal vessels, making them brittle and prone to leakage.

This is why early signs often include dry eyes, mild redness, and tiny dot hemorrhages.

As the condition deepens, the Spleen's ability to produce Qi from food also falters, leading to a dual depletion of Qi and Yin. The energy that should hold blood within the vessels grows too weak, while the nourishing fluids that keep vessels supple run dry - a combination that produces cotton-wool spots, more widespread bleeding, and fatigue.

At any stage, sluggish blood flow can congeal into Blood Stagnation, a pattern of sticky, congealed circulation that blocks nourishment to the retina and fuels the growth of fragile new vessels. This is why hard exudates, large hemorrhages, and abnormal vessel growth are seen as blood stasis complicating the underlying deficiency.

In advanced disease, the body's reserves are so drained that even the warming Yang of the Kidneys becomes depleted. The retina then suffers from a lack of both nourishment and warmth, leading to severe ischemia and a pale, puffy tongue with cracks - a sign of deep exhaustion.

TCM's strength is that it sees this progression not as one monolithic disease but as a sequence of shifting patterns, each needing a different treatment focus: nourishing Yin early, then supplementing Qi and moving blood, and later warming and restoring both Yin and Yang.

From the classical texts

「其病变多发痈疽,或为目疾,至甚则盲。」

"When the disease lingers, it often produces abscesses and deep-rooted sores, or becomes an eye disorder, and in severe cases leads to blindness."

Zhu Bing Yuan Hou Lun (诸病源候论) , Volume 5, Treatise on Xiao Ke (Wasting-Thirst) · More references

How a TCM practitioner diagnoses diabetic retinopathy

Inside the consultation

A practitioner starts by looking for the root pattern of Empty-Heat or Fire caused by Yin Deficiency, which typically appears in the early background stage. You might notice dry, slightly red eyes, occasional blurring, or tiny floaters. The tongue is red with a thin or absent coat, and the pulse feels thin and rapid, confirming that Yin is too weak to anchor the body’s warming function.

As the condition moves toward the preproliferative stage, Qi and Yin Deficiency becomes more prominent. You may feel unusually tired and short of breath, and your vision might decline more noticeably, sometimes with dark spots. The tongue appears pale and puffy with tooth marks, and the pulse is thin and forceless, showing that both vital energy and nourishing fluids are depleted.

Blood Stagnation is a key complication that can develop at any stage, but becomes more obvious when there are visible retinal hemorrhages, hard yellowish exudates, or abnormal new vessel growth. The tongue often turns dark purple or shows stasis spots, and the pulse may feel choppy and uneven. This pattern rarely stands alone - it usually overlays one of the underlying deficiency states.

In the advanced proliferative stage, long-standing Yin damage eventually weakens Yang, leading to a combined Kidney Yin and Yang Deficiency. This pattern is associated with severe ischemia, neovascular glaucoma, and a high risk of vitreous hemorrhage. You may feel cold, experience frequent night-time urination, and notice swelling. The tongue is pale and puffy, and the pulse is deep, slow, and weak.

TCM Patterns for Diabetic Retinopathy

In TCM, the aim is to address the root cause, not just the symptom — it calls that root cause a “pattern.” The same diabetic retinopathy can come from several different patterns, each treated differently. The quickest way to find yours is the quiz below.

Find your pattern

Tap any sign that fits how yours feels.

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  1. 1Your signs
  2. 2What makes it worse
  3. 3What helps

Which signs match your experience?

0 selected this step
Dry, gritty eyes and blurred vision Night sweats and warm palms and soles Thirst with a desire for small sips of water Tiny dot hemorrhages or microaneurysms on eye exam Red tongue with little or no coating
Worse with Late nights and overwork, Spicy, greasy, or fried foods, Emotional stress and anger, Hot, dry weather
Better with Cool, humid environments, Regular, gentle eye rest, Yin-nourishing foods
Gradual blurring of vision, worse when tired Persistent fatigue and lack of strength Dry mouth with little desire to drink Spontaneous daytime sweating or night sweats Shortness of breath on exertion
Worse with Overexertion and long working hours, Mental stress and worry, Spicy, drying, or fried foods, Irregular eating and skipping meals, Prolonged screen time without breaks
Better with Adequate rest and sleep, Warm, easily digested meals, Gentle daily movement, Stress reduction
Retinal hemorrhages (dot, blot, or flame-shaped) Hard exudates in the retina Fixed, dull ache or pressure behind the eye Vision loss or visual field defects Dark purple tongue with stasis spots
Worse with Cold exposure, Prolonged sitting or inactivity, Stress and frustration, High blood sugar
Better with Warmth (promotes circulation), Gentle daily movement, Blood-nourishing foods (dark greens, lean meats)
Severe vision loss with risk of vitreous hemorrhage Lower back cold and aching, weak knees Alternating chills and hot flushes Deep fatigue and lack of vitality Frequent nighttime urination
Worse with Overwork and exhaustion, Cold raw foods and iced drinks, Exposure to cold weather, Excessive sexual activity, Stress and anxiety
Better with Warmth and rest, Gentle exercise like tai chi, Warm nourishing foods (bone broth, lamb), Keeping the lower back warm

Treatment

Four ways to address diabetic retinopathy in TCM — explore each, or take the quiz to see what fits you first.

Formulas traditionally used for diabetic retinopathy

5 formulas across the patterns above. The right one depends on your pattern — start with the quiz if you're unsure which fits.

Zhi Bai Di Huang Wan Anemarrhena, Phellodendron, and Rehmannia Pill · Míng dynasty, 1584 CE
Cool
Nourishes Yin Clears Deficiency Heat Nourishes Kidney Yin

A classical formula that nourishes the body's cooling Yin fluids while clearing excess internal heat. It is commonly used for symptoms such as hot flashes, night sweats, tinnitus, sore throat, dry mouth, and low back aching that arise when the Kidneys become depleted and the body overheats from within. It builds on the famous Liu Wei Di Huang Wan (Six Ingredient Rehmannia Pill) with two additional cooling herbs.

Patterns
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Sheng Mai San Generate the Pulse Powder · Jīn dynasty, ~1186 CE
Slightly Warm
Tonifies Qi Generates Fluids Nourishes Yin

A classical three-herb formula used to restore vitality when both Qi and body fluids have been depleted. It addresses fatigue, shortness of breath, excessive sweating, dry throat, and weak pulse caused by heat exhaustion, chronic illness, or prolonged coughing that has weakened the Lungs. In modern practice, it is also widely used as supportive treatment for heart conditions including heart failure and irregular heartbeat.

Patterns
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Ming Mu Di Huang Wan Rehmannia Pill to Brighten the Eyes · Míng dynasty, 1644 CE
Slightly Cool
Nourishes Kidney Yin Nourishes Liver Blood Brightens the Eyes

A classical formula designed to nourish the Liver and Kidneys in order to support eye health. It is used for symptoms such as dry or gritty eyes, sensitivity to light, blurred vision, and watery eyes caused by Wind, all stemming from an underlying deficiency of Liver and Kidney Yin. It builds on the well-known Liu Wei Di Huang Wan (Six-Ingredient Pill with Rehmannia) by adding herbs that specifically benefit the eyes, nourish the Blood, and calm overactive Liver Yang.

Patterns
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Tao Hong Si Wu Tang Peach Pit and Carthamus Four-Substance Decoction · Yuán dynasty, ~1291 CE
Warm
Invigorates Blood and Dispels Stasis Nourishes Blood Regulates menstruation

A classical formula that both nourishes and invigorates the Blood, used to address menstrual irregularities, period pain, and other conditions caused by Blood stagnation combined with Blood deficiency. It builds on the famous Si Wu Tang (Four-Substance Decoction) by adding Peach Kernel and Safflower to strengthen its ability to move stagnant Blood and promote healthy circulation.

Patterns
Shop · from $23
Jin Gui Shen Qi Wan Golden Cabinet Kidney Qi Pill · Eastern Hàn dynasty, circa 200 CE
Warm
Tonifies Kidney Yang Warms Yang and Transforms Qi Warms the Ming Men Fire

A classical formula that gently warms and supports the Kidneys to restore vitality, fluid balance, and lower body warmth. It is used for people with Kidney weakness who experience lower back soreness, cold legs, frequent urination or difficulty urinating, and general fatigue. Unlike strong warming formulas, it uses a small amount of warming herbs alongside a larger base of nourishing ingredients, working gradually to restore the body's natural balance.

Patterns
Typical timeline for diabetic retinopathy

In early non-proliferative stages, many patients notice less eye dryness and clearer vision within 4-8 weeks of consistent herbs and acupuncture. Retinal changes visible on exam take longer - typically 3-6 months for stabilization of hemorrhages and exudates when the pattern is primarily Yin deficiency or Qi and Yin deficiency. Advanced proliferative disease with Blood Stagnation and mixed deficiency patterns requires a longer commitment, often 6-12 months, to support the eye while working alongside conventional care.

Treatment principles

Across all patterns, the treatment of diabetic retinopathy rests on two pillars: nourishing what has been depleted and clearing what has accumulated. The underlying depletion is almost always Yin, often spreading to Qi and eventually Yang, so formulas center on herbs that moisten, cool, and rebuild the body's reserves - like Shu Di Huang, Gou Qi Zi, and Mai Dong.

At the same time, the heat and blood stasis that complicate the picture must be gently cleared using herbs like Dan Shen, San Qi, and Zhi Mu, so the retina's tiny vessels can heal.

What changes from pattern to pattern is the emphasis. In early Yin deficiency with Empty-Heat, the priority is cooling and moistening. When Qi and Yin are both low, treatment adds Spleen-strengthening herbs like Huang Qi and Shan Yao to lift the energy that holds blood in place.

When Blood Stagnation dominates, blood-moving herbs take center stage, always supported by enough nourishment to avoid further damage. This layered, adaptable approach is what makes TCM uniquely suited to a condition that evolves over many years.

What to expect from treatment

Most patients begin with weekly acupuncture and daily herbal formulas, taken as teas, powders, or easy-to-swallow granules. You may notice subtle shifts first - less eye dryness, better sleep, more stable energy - often within 2-4 weeks. The retinal changes that matter most take longer to stabilize, typically 3-6 months, and your ophthalmologist will track these through regular eye exams.

Progress is rarely linear. You might have a period of clear improvement followed by a plateau, which is normal as the body integrates deeper healing. The key is consistency, because TCM is gradually rebuilding the internal terrain that allowed the retinopathy to develop, not just suppressing a symptom.

General dietary guidance

The best diet for diabetic retinopathy from a TCM perspective is one that cools and moistens the body while supporting stable blood sugar. Favor Yin-nourishing foods: steamed leafy greens, goji berries, black sesame, cucumber, pear, and moderate amounts of fish or duck. These help replenish the fluids that long-standing diabetes has consumed.

At the same time, avoid foods that add heat or dampness - spicy peppers, deep-fried dishes, excessive alcohol, and greasy meats. Eat at regular times, chew thoroughly, and don't overload the stomach, because the Spleen's ability to transform food into usable Qi is already compromised. Small, warm, cooked meals are more supportive than large, cold, raw ones.

Combining TCM with conventional treatment

TCM treatment for diabetic retinopathy is designed to complement, not replace, your conventional medical care. Continue all prescribed medications, eye injections, and regular ophthalmology appointments. Herbal formulas that contain blood-moving herbs like Dan Shen or San Qi may have a mild blood-thinning effect, so if you are taking anticoagulants or antiplatelet drugs, both your TCM practitioner and your prescribing doctor must be aware.

Because some herbs can gently lower blood sugar, monitor your levels when starting treatment and share your full herbal list with your endocrinologist. With open communication, TCM and Western medicine can work hand in hand - one stabilizing the eye from within, the other intervening with precision when sight is acutely threatened.

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Safety & special considerations

Seek urgent medical care — not a TCM practitioner — if you have:
  • Sudden loss of vision in one eye — may indicate a major hemorrhage or retinal artery occlusion; requires immediate ophthalmological evaluation
  • A sudden shower of new floaters or flashes of light — often signals a retinal tear or detachment, which can lead to permanent vision loss if not treated urgently
  • A dark curtain or shadow moving across your field of vision — classic sign of retinal detachment; go to an emergency room or eye casualty immediately
  • Severe eye pain with redness and headache — could be acute glaucoma, especially if accompanied by nausea; requires urgent pressure-lowering treatment
  • Any vision change that occurs suddenly or worsens over hours rather than weeks — acute changes need prompt assessment to rule out sight-threatening events

Audience-specific guidance — open what applies to you

Evidence & references

Acupuncture and Chinese herbal medicine show promise for diabetic retinopathy, but the overall evidence quality is moderate. A 2018 meta-analysis of Qi Ming granule, a widely used TCM formula, found significant improvements in visual acuity and a reduction in retinal microaneurysms when added to conventional treatment.

Several small randomized controlled trials suggest that acupuncture can improve retinal blood flow and visual function. However, many studies are limited by small sample sizes, lack of blinding, and short follow-up periods.

Preclinical research provides mechanistic support. For example, the formula Bie-Jia-Ruan-Mai-Tang has been shown to inhibit retinal neovascularization and induce apoptosis of retinal vascular endothelial cells in diabetic mice. While these findings are encouraging, well-designed, large-scale clinical trials are still needed to confirm efficacy and safety. Patients should use TCM as a complementary therapy alongside standard ophthalmologic and diabetic care.

Key clinical studies

Bottom line for you

This preclinical study demonstrated that Bie-Jia-Ruan-Mai-Tang significantly reduced retinal neovascularization in a mouse model of diabetic retinopathy by promoting apoptosis of pathological endothelial cells, providing a mechanistic basis for its traditional use.

Bie-Jia-Ruan-Mai-Tang, a Chinese Medicine Formula, Inhibits Retinal Neovascularization in Diabetic Mice Through Inducing the Apoptosis of Retinal Vascular Endothelial Cells

Chen L, et al. Evidence-Based Complementary and Alternative Medicine. 2022.

https://pmc.ncbi.nlm.nih.gov/articles/PMC9314569

Classical text references

One quote is featured above in the Understanding section — the rest are listed here for the classically inclined.

「男子消渴,小便反多,以饮一斗,小便一斗,肾气丸主之。」

"In men with wasting-thirst, there is copious urine; they drink one dou of water and pass one dou of urine. Kidney Qi Pill governs this."

Jin Gui Yao Lue (金匮要略)
Chapter 13, Xiao Ke Xiao Bian Bu Li (Wasting-Thirst and Urinary Difficulty)

Frequently asked questions

Common questions about using Traditional Chinese Medicine for diabetic retinopathy.

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