Formula

Ming Mu Di Huang Wan

Rehmannia Vision Formula | 明目地黄丸

Also known as:

Improve Vision Pill with Rehmannia pill , Nourish Vision with Rehmannia

Properties

Yin-tonifying formulas · Slightly Cool

Key Ingredients

Shu Di Huang

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

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About This Formula

Traditional Chinese Medicine background and properties

Formula Description

A classical formula designed to nourish the Liver and Kidneys in order to support eye health. It is used for symptoms such as dry or gritty eyes, sensitivity to light, blurred vision, and watery eyes caused by Wind, all stemming from an underlying deficiency of Liver and Kidney Yin. It builds on the well-known Liu Wei Di Huang Wan (Six-Ingredient Pill with Rehmannia) by adding herbs that specifically benefit the eyes, nourish the Blood, and calm overactive Liver Yang.

Formula Category

Main Actions

  • Nourishes Kidney Yin
  • Nourishes Liver Blood
  • Brightens the Eyes
  • Calms the Liver and Subdues Yang
  • Clears Deficiency Heat from the Liver

TCM Patterns

In TCM, symptoms don't appear randomly — they cluster into recognizable patterns of disharmony that reveal what's out of balance in the body. Ming Mu Di Huang Wan is traditionally associated with these specific patterns.

The following describes this formula's classification within Traditional Chinese Medicine theory and is provided for educational purposes only.

Why Ming Mu Di Huang Wan addresses this pattern

When the Yin of both the Liver and Kidneys becomes depleted, the eyes lose their source of nourishment. In TCM, the Kidneys store Essence that generates marrow and nourishes the brain, while the Liver stores Blood and opens to the eyes. When Kidney Yin is insufficient, it fails to nourish Liver Yin, leading to a combined deficiency. The eyes, being the sensory opening of the Liver, are among the first organs to show signs of this depletion: dryness, grittiness, blurred vision, and light sensitivity.

Ming Mu Di Huang Wan addresses this through its Liu Wei Di Huang Wan base, which deeply replenishes Kidney Yin with Shu Di Huang, Shan Zhu Yu, and Shan Yao. The added herbs (Gou Qi Zi, Dang Gui, Bai Shao) specifically direct nourishment to the Liver and its Blood, while Ju Hua, Ji Li, and Shi Jue Ming clear and calm the Liver to benefit the eyes directly. The formula thus treats both the root (Kidney and Liver Yin deficiency) and the branch (eye symptoms).

A practitioner would look for one or more of these signs

Blurry Vision

Gradual onset, worse with prolonged use of the eyes

Dry Eyes

Gritty or sandy sensation, reduced tear production

Photophobia

Sensitivity to light, discomfort in bright environments

Excessive Sweating

Watering of the eyes when exposed to wind (迎风流泪)

Dizziness

Light-headedness from Yin deficiency failing to anchor Yang

Tinnitus

Ringing in the ears from Kidney Yin deficiency

Lower Back Pain

Soreness and weakness of the lower back and knees

Night Sweats

Reflecting deficiency Heat from depleted Yin

How It Addresses the Root Cause

In TCM, the eyes depend on nourishment from the Liver and Kidneys more than any other organ pair. The Liver stores Blood and "opens to the eyes" (肝开窍于目), meaning the Liver supplies Blood and Yin fluids that keep the eyes moist, comfortable, and able to see clearly. The Kidneys store Essence (Jing), which is the deepest source of Yin in the body and provides the foundation for all the body's fluids and nourishing substances. When Kidney Essence is abundant, it generates sufficient Yin to support the Liver and ultimately the eyes.

When the Kidneys weaken over time (from aging, overwork, chronic illness, or constitutional factors), Kidney Yin becomes depleted. Because the Liver and Kidneys share a common Yin foundation (a relationship described as "Liver and Kidney share the same source," 肝肾同源), Kidney Yin depletion inevitably leads to Liver Yin and Liver Blood insufficiency. Without enough Liver Blood to nourish them, the eyes become dry, gritty, and light-sensitive. Vision grows blurry. Furthermore, when Yin is insufficient, it can no longer properly restrain Yang. Deficiency Heat or mildly rising Liver Yang develops, causing the eyes to tear when exposed to wind. In essence, the root of the problem is below (in the Kidneys), but the symptoms manifest above (in the eyes).

Ming Mu Di Huang Wan addresses this by replenishing the depleted Kidney Yin and Liver Blood at their source, while simultaneously calming Liver Yang and clearing mild Deficiency Heat that disturbs the eyes, thereby restoring proper nourishment to the visual system from the ground up.

Formula Properties

Temperature

Slightly Cool

Taste Profile

Predominantly sweet and slightly bitter, with sour and astringent undertones. Sweet to nourish and tonify, bitter to gently clear Heat, sour to astringently preserve Essence.

Target Organs
Liver Kidneys Spleen
Channels Entered
Liver Kidney Spleen

Formula Origin

Shěn Shì Yáo Hán (审视瑶函, Discerning Patterns and Guiding Remedies for the Eyes) by Fù Rényǔ (傅仁宇)

This is just partial information on the formula's TCM properties. More detailed information is available on the formula's dedicated page

Ingredients in Ming Mu Di Huang Wan

Detailed information about each herb in Ming Mu Di Huang Wan and their roles

Kings
Deputies
Assistants
Envoys
Shu Di Huang
Shu Di Huang

Prepared Rehmannia root

Dosage: 12 - 24g

Temperature Slightly Warm
Taste Sweet (甘 gān)
Organ Affinity Liver, Kidneys
Parts Used Tuber (块茎 kuài jīng / 块根 kuài gēn)
Role in Ming Mu Di Huang Wan

Strongly enriches Kidney Yin and nourishes Liver Blood, providing the root-level replenishment of Yin and Essence that the eyes depend on for moisture and clear vision.

Shan Zhu Yu
Shan Zhu Yu

Cornelian Cherry Fruit

Dosage: 6 - 12g

Temperature Slightly Warm
Taste Sour (酸 suān), Astringent (涩 sè)
Organ Affinity Liver, Kidneys
Parts Used Fruit (果 guǒ / 果实 guǒ shí)
Role in Ming Mu Di Huang Wan

Nourishes Liver and Kidney Yin and restrains the leakage of Essence, reinforcing the tonifying action of Shu Di Huang while stabilizing the Liver.

Shan Yao
Shan Yao

Chinese yam

Dosage: 6 - 12g

Temperature Neutral
Taste Sweet (甘 gān)
Organ Affinity Spleen, Lungs, Kidneys
Parts Used Rhizome (根茎 gēn jīng)
Role in Ming Mu Di Huang Wan

Tonifies the Spleen and Kidneys, stabilizing postnatal Essence production and ensuring the body can generate and transport the nourishment the eyes need.

Gou Qi Zi
Gou Qi Zi

Chinese Wolfberry Fruit

Dosage: 6 - 12g

Temperature Neutral
Taste Sweet (甘 gān)
Organ Affinity Liver, Kidneys, Lungs
Parts Used Fruit (果 guǒ / 果实 guǒ shí)
Role in Ming Mu Di Huang Wan

Nourishes Liver and Kidney Yin, enriches the Essence and Blood, and directly benefits the eyes. A premier eye-nourishing herb that bridges the Kidney-tonifying base with the eye-focused therapeutic strategy.

Ju Hua
Ju Hua

Chrysanthemum flower

Dosage: 6 - 9g

Temperature Slightly Cool
Taste Sweet (甘 gān), Bitter (苦 kǔ)
Organ Affinity Lungs, Liver
Parts Used Flower (花 huā)
Role in Ming Mu Di Huang Wan

Clears Liver Heat, disperses Wind from the head and eyes, and brightens the vision. Paired with Gou Qi Zi, it directs the formula's action upward to the eyes.

Dang Gui
Dang Gui

Chinese Angelica root

Dosage: 6 - 9g

Temperature Warm
Taste Sweet (甘 gān), Acrid / Pungent (辛 xīn)
Organ Affinity Liver, Heart, Spleen
Parts Used Root (根 gēn)
Role in Ming Mu Di Huang Wan

Nourishes and moves the Blood, ensuring adequate Blood supply to the eyes. Addresses Liver Blood deficiency, which is a key component of eye symptoms in this pattern.

Bai Shao
Bai Shao

White peony root

Dosage: 6 - 9g

Temperature Slightly Cool
Taste Bitter (苦 kǔ), Sour (酸 suān)
Organ Affinity Liver, Spleen
Parts Used Root (根 gēn)
Role in Ming Mu Di Huang Wan

Nourishes Liver Blood, softens and restrains Liver Yang from rising, and works with Dang Gui to comprehensively address Blood deficiency affecting the eyes.

Ji Li
Ji Li

Tribulus fruit

Dosage: 6 - 9g

Temperature Slightly Warm
Taste Acrid / Pungent (辛 xīn), Bitter (苦 kǔ)
Organ Affinity Liver
Parts Used Fruit (果 guǒ / 果实 guǒ shí)
Role in Ming Mu Di Huang Wan

Calms the Liver, disperses Wind, and brightens the eyes. Helps relieve eye symptoms like itching, redness, and tearing caused by Liver Wind or rising Liver Yang.

Shi Jue Ming
Shi Jue Ming

Abalone shell

Dosage: 9 - 15g

Temperature Cold
Taste Salty (咸 xián)
Organ Affinity Liver
Parts Used Shell (壳 ké / 甲 jiǎ)
Role in Ming Mu Di Huang Wan

A heavy mineral substance that anchors and subdues rising Liver Yang, clears Liver Heat obstructing the vision, and directly benefits the eyes. Its weight helps pull down excess Yang that floats upward to disturb the eyes.

Mu Dan Pi
Mu Dan Pi

Tree peony root bark

Dosage: 6 - 9g

Temperature Slightly Cool
Taste Bitter (苦 kǔ), Acrid / Pungent (辛 xīn)
Organ Affinity Heart, Liver, Kidneys
Parts Used Bark (皮 pí / 树皮 shù pí)
Role in Ming Mu Di Huang Wan

Clears deficiency Heat from the Liver and Kidney, cools the Blood, and prevents the formula's rich tonifying herbs from generating stagnant Heat.

Fu Ling
Fu Ling

Poria

Dosage: 6 - 9g

Temperature Neutral
Taste Sweet (甘 gān), Bland (淡 dàn)
Organ Affinity Heart, Lungs, Spleen, Kidneys
Parts Used Fungus / Mushroom (菌类 jūn lèi)
Role in Ming Mu Di Huang Wan

Drains Dampness and supports the Spleen's transport function, preventing the rich, cloying tonifying herbs from overwhelming digestion. Helps Shan Yao strengthen the Spleen.

Ze Xie
Ze Xie

Water plantain rhizome

Dosage: 6 - 9g

Temperature Cold
Taste Sweet (甘 gān), Bland (淡 dàn)
Organ Affinity Kidneys, Urinary Bladder
Parts Used Tuber (块茎 kuài jīng / 块根 kuài gēn)
Role in Ming Mu Di Huang Wan

Drains Dampness and clears turbidity from the Kidneys, preventing the heavy tonifying properties of Shu Di Huang from creating congestion. Directs excess downward and out via urination.

Modern Research (2 studies)

  • Ming-Mu-Di-Huang-Pill Activates SQSTM1 via AMPK-Mediated Autophagic KEAP1 Degradation and Protects RPE Cells from Oxidative Damage (In vitro/in vivo study, 2022)
  • Evidence-based Practice Guideline of Chinese Herbal Medicine for Primary Open-Angle Glaucoma (Guideline, 2018)
See all research on the formula page

Usage & Safety

How to use this formula and important safety information

Important Medical Disclaimer

The information provided here is for educational purposes only and is not intended as medical advice or to replace consultation with a qualified healthcare professional. This formula is a dietary supplement and has not been evaluated by the FDA. It is not intended to diagnose, treat, cure, or prevent any disease.

Always consult with a qualified healthcare provider, particularly if you are pregnant, nursing, have a medical condition, or are taking other medications. Discontinue use and consult your healthcare provider if you experience any adverse reactions.

Recommended Dosage

Instructions for safe storage and consumption

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Best Time to Take

Best taken on an empty stomach, typically 30 minutes before meals, twice or three times daily.

Typical Duration

Often taken for 4 weeks per course, with reassessment by a practitioner. May be continued for 2-3 months for chronic conditions, with periodic breaks.

Dietary Advice

Avoid cold and raw foods, greasy or fried foods, and excessive spicy or pungent foods that can generate Heat or burden the Spleen. The classical source text specifically advises against eating turnips (luobo) while taking this formula, as they are thought to counteract the tonifying action of the herbs. Favor dark leafy greens, berries, goji berries, black sesame seeds, and other foods that nourish Liver Blood and Kidney Yin. Adequate hydration supports the Yin-nourishing actions of the formula.

Modern Usage

Ming Mu Di Huang Wan nourishes the Kidneys, supports the Liver, and improves vision. It is used for Liver and Kidney Yin Deficiency, with symptoms such as dry eyes, sensitivity to light, blurred vision, and tearing in the wind.

Special Populations

Pregnancy

Use with caution during pregnancy. Dang Gui (Angelica sinensis) has mild Blood-moving properties that could theoretically stimulate uterine activity at high doses. Mu Dan Pi (Moutan bark) also mildly invigorates Blood. While the formula as a whole is gentle and primarily nourishing, it is prudent for pregnant individuals to consult a qualified practitioner before use. Not absolutely contraindicated, but not recommended for unsupervised use during pregnancy.

Breastfeeding

Generally considered safe during breastfeeding. The formula is composed of nourishing, supplementing herbs without known toxic components that would transfer in clinically significant amounts through breast milk. The mild Blood-nourishing herbs (Dang Gui, Bai Shao) may even support postpartum Blood recovery. However, the rich, cloying nature of the formula could theoretically affect digestion in those with a sensitive constitution. Consult a practitioner if any concerns arise.

Pediatric Use

Children should have a proper eye examination before taking this formula to rule out other conditions. Dosage should be reduced proportionally by age and body weight, typically to one-third to one-half the adult dose for children over 6. Not typically used in very young children (under 3) without specific practitioner guidance, as the rich Yin-nourishing herbs may be difficult for immature digestive systems. If symptoms such as rapid vision decline occur, discontinue and seek immediate ophthalmological evaluation. A 4-week course is standard, with reassessment needed if no improvement is seen within one week.

Drug Interactions

Anticoagulants and antiplatelet drugs: Dang Gui (Angelica sinensis) has demonstrated mild anticoagulant activity and may potentiate the effects of warfarin, heparin, aspirin, or other blood-thinning medications, increasing bleeding risk. Monitor INR if taken concurrently with warfarin.

Antihypertensive medications: Several ingredients (Mu Dan Pi, Ze Xie, Ju Hua, Shi Jue Ming) have mild blood pressure-lowering effects. Combined use with antihypertensive drugs may cause additive hypotension. Blood pressure should be monitored.

Hypoglycemic agents: Shu Di Huang and Shan Yao have been reported to have mild blood sugar-lowering properties. Diabetic patients on insulin or oral hypoglycemics should monitor blood glucose more closely when starting this formula.

Diuretics: Ze Xie and Fu Ling promote urination. Concurrent use with pharmaceutical diuretics could lead to excessive fluid loss or electrolyte imbalance.

Contraindications

Avoid

Acute conjunctivitis (暴发火眼) with red, congested eyes, excessive discharge, and acute inflammation. This formula nourishes Yin deficiency and is not appropriate for acute excess-Heat eye conditions.

Avoid

Eye conditions caused by external Wind-Heat invasion or Damp-Heat accumulation. This formula addresses internal deficiency, not external excess pathogens.

Caution

Spleen deficiency with pronounced digestive weakness, loose stools, or poor appetite. The rich, Yin-nourishing herbs (especially Shu Di Huang) are heavy and cloying, and may further burden a weak Spleen. The formula should be modified or combined with Spleen-supporting herbs if needed.

Caution

Cold-Dampness patterns or Kidney Yang deficiency with cold extremities and clear, copious urination. This cooling, Yin-nourishing formula would worsen Yang deficiency.

Caution

Active cold or flu (common cold) with exterior symptoms. Tonifying formulas should generally be withheld until the exterior pathogen is resolved.

Cautions & Warnings

Although this formula is typically safe for most individuals, it may cause side effects in some people. Pregnant women, nursing mothers, postpartum women, and those with liver disease should use the formula with caution.

As with any Chinese herbal remedy, it is advisable to seek guidance from a qualified TCM practitioner before beginning treatment.

Product Details

Manufacturing, supplier, and product specifications

Product Type

Granules

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Treasure of the East

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