Jiao Ai Tang

Ass-Hide Gelatin and Mugwort Decoction · 胶艾汤

Also known as: Xiong Gui Jiao Ai Tang (芎归胶艾汤, Cnidium and Angelica Gelatin and Mugwort Decoction), Jiao Ai Si Wu Tang (胶艾四物汤)

A classical formula from the Jin Gui Yao Lue used to nourish Blood, warm the uterus, and stop bleeding. It is primarily used for women experiencing prolonged or excessive menstrual bleeding, spotting between periods, bleeding during pregnancy (threatened miscarriage), or post-miscarriage bleeding, especially when these occur alongside signs of Blood deficiency and coldness in the lower abdomen.

Origin Jin Gui Yao Lue (金匮要略, Essentials from the Golden Cabinet) by Zhang Zhongjing — Eastern Han dynasty (东汉), circa 200 CE
Composition 7 herbs
E Jiao
King
E Jiao
Ai Ye
King
Ai Ye
Dang Gui
Deputy
Dang Gui
Di Huang
Deputy
Di Huang
Bai Shao
Assistant
Bai Shao
Chuan Xiong
Assistant
Chuan Xiong
Gan Cao
Envoy
Gan Cao
Explore composition

Educational content Consult qualified TCM practitioners for diagnosis and treatment

Patterns Addressed

In TCM, symptoms don't appear randomly — they cluster into recognizable patterns of disharmony that reveal what's out of balance in the body. Jiao Ai Tang is designed to correct these specific patterns.

Why Jiao Ai Tang addresses this pattern

This is the primary pattern for Jiao Ai Tang. When the Chong (Thoroughfare) and Ren (Conception) vessels are depleted and unable to regulate Blood, the uterus loses its ability to contain Blood properly. E Jiao and Ai Ye directly replenish and stabilize these vessels, with E Jiao nourishing the Blood and Yin substance of the Chong and Ren, and Ai Ye warming them to restore their holding function. The Si Wu Tang base (Dang Gui, Bai Shao, Gan Di Huang, Chuan Xiong) reinforces the Blood supply that the Chong and Ren depend on, while Gan Cao strengthens the Spleen to support its role in maintaining Blood within the vessels.

A practitioner would look for one or more of these signs

Uterine Bleeding

Prolonged, pale, watery uterine bleeding

Menstrual Irregularity

Excessive menstrual flow or prolonged periods

Threatened Miscarriage

Vaginal bleeding during pregnancy with lower abdominal pain

Abdominal Pain

Dull, cold pain in the lower abdomen relieved by warmth

Fatigue

Fatigue and pallor from chronic blood loss

Commonly Prescribed For

These conditions can arise from the patterns above. A practitioner would consider Jiao Ai Tang when these conditions are specifically caused by those patterns — not for all cases of these conditions.

Arises from: Chong and Ren Vessels Deficiency Blood Deficiency

TCM Interpretation

In TCM, threatened miscarriage ('fetal leakage', 胎漏, or 'fetal restlessness', 胎动不安) is understood as a failure of the Chong and Ren vessels to secure and nourish the developing fetus. The Chong vessel is called the 'Sea of Blood' and provides the rich blood supply that sustains pregnancy. When these vessels are weakened, whether from constitutional weakness, overwork, or prior pregnancies, they cannot maintain their grip on the fetus. Blood leaks downward, and the lower abdomen may ache or feel heavy. The Kidney, which stores the Essence that underlies reproductive capacity, is also typically involved, as Kidney Yang provides the warmth needed to incubate the fetus.

Why Jiao Ai Tang Helps

Jiao Ai Tang directly targets the Chong and Ren vessels. E Jiao nourishes the Blood and 'seals' the leaking vessels with its rich, sticky quality, while Ai Ye warms the uterus and stabilizes the pregnancy from a Yang perspective. Together, they calm the fetus and stop vaginal bleeding. The Si Wu Tang backbone (Dang Gui, Bai Shao, Gan Di Huang, Chuan Xiong) ensures a steady supply of nourishing Blood to support both the mother and the developing baby. Clinical research has confirmed this formula's effectiveness: a study at Osaka Medical College found that women receiving Jiao Ai Tang achieved uterine hemostasis significantly faster than those receiving hCG injections alone.

Also commonly used for

Menstrual Irregularity

Excessive or prolonged menstrual periods

Recurrent Miscarriage

Habitual miscarriage with bleeding

Postpartum Bleeding

Persistent lochia or postpartum hemorrhage

Endometriosis

When presenting with deficiency-type bleeding

Thrombocytopenia

Idiopathic thrombocytopenic purpura

Peptic Ulcer

Peptic ulcer with bleeding (deficiency-Cold type)

What This Formula Does

Every TCM formula has a specific set of actions — here's what Jiao Ai Tang does in the body, explained in both everyday and TCM terms

Therapeutic focus

In practical terms, Jiao Ai Tang is primarily used to support these areas of health:

TCM Actions

In TCM terminology, these are the specific therapeutic actions that Jiao Ai Tang performs to restore balance in the body:

How It Addresses the Root Cause

TCM doesn't just suppress symptoms — it aims to resolve the underlying imbalance. Here's how Jiao Ai Tang works at the root level.

This formula addresses a core pattern where the Chong Mai (Thoroughfare Vessel) and Ren Mai (Conception Vessel) become weakened and unable to regulate Blood properly. The Chong and Ren are the two extraordinary vessels that govern menstruation, fertility, and pregnancy in women. When they are damaged, whether by constitutional weakness, chronic illness, overwork, or physical trauma, Blood loses its normal containment and begins to leak downward from the uterus.

The underlying mechanism has two intertwined components. First, there is Blood deficiency: the body lacks sufficient Blood to nourish the vessels and keep them strong, creating a vicious cycle where bleeding leads to further Blood loss. Second, there is often Cold in the uterus (often described as 'deficiency Cold'): when Yang is insufficient to warm the lower body, the uterus becomes cold and unstable, failing to hold Blood in place or to secure a developing fetus. This is why this type of bleeding tends to be pale and watery rather than bright red, and is often accompanied by a cold sensation in the lower abdomen, a pale tongue, and a thin or weak pulse.

The formula works by simultaneously replenishing the depleted Blood, warming the uterine environment, and gently astringing the leaking vessels, addressing both the root deficiency and the immediate symptom of bleeding.

Formula Properties

Every formula has an inherent temperature, taste, and affinity for specific organs — these properties determine how it interacts with the body

Overall Temperature

Warm

Taste Profile

Predominantly sweet and slightly bitter — sweet to nourish Blood and tonify deficiency, with mild bitterness and acrid warmth from Ai Ye and Chuan Xiong to move Qi and warm the channels.

Channels Entered

Liver Spleen Kidney Chong Mai (冲脉) Penetrating Vessel Ren Mai (任脉) Conception Vessel

Ingredients

7 herbs

The herbs that make up Jiao Ai Tang, organized by their role in the prescription

King — Main ingredient driving the formula
Deputy — Assists and enhances the King
Assistant — Supports or moderates other herbs
Envoy — Directs the formula to its target
Kings — Main ingredient driving the formula
E Jiao

E Jiao

Donkey-hide gelatin

Dosage 9 - 15g
Temperature Neutral
Taste Sweet (甘 gān)
Organ Affinity Lungs, Liver, Kidneys
Preparation Dissolved into the strained decoction at the end (烊化, yang hua). Do not decoct with the other herbs.

Role in Jiao Ai Tang

Nourishes Blood, enriches Yin, and directly stops bleeding. As the formula's namesake, it replenishes the depleted Blood of the Chong and Ren vessels and has a sticky, consolidating quality that helps seal leaking blood vessels. It addresses both the root cause (Blood deficiency) and the branch symptom (bleeding).
Ai Ye

Ai Ye

Mugwort leaf

Dosage 6 - 10g
Temperature Warm
Taste Acrid / Pungent (辛 xīn), Bitter (苦 kǔ)
Organ Affinity Liver, Spleen, Kidneys

Role in Jiao Ai Tang

Warms the channels and uterus, stops bleeding, and calms the fetus. Its warm nature directly addresses the Cold that destabilizes the Chong and Ren vessels. Working together with E Jiao, it provides the warm, Yang aspect to stop bleeding and secure the womb while E Jiao provides the nourishing, Yin aspect.
Deputies — Assists and enhances the King
Dang Gui

Dang Gui

Chinese Angelica root

Dosage 9 - 12g
Temperature Warm
Taste Sweet (甘 gān), Acrid / Pungent (辛 xīn)
Organ Affinity Liver, Heart, Spleen

Role in Jiao Ai Tang

Tonifies Blood and promotes Blood circulation without causing excessive movement. It reinforces the Blood-nourishing action of E Jiao while ensuring that the newly formed Blood flows smoothly through the vessels rather than becoming stagnant, an important consideration in any bleeding condition.
Di Huang

Di Huang

Rehmannia root

Dosage 15 - 30g
Temperature Cold
Taste Sweet (甘 gān), Bitter (苦 kǔ)
Organ Affinity Heart, Liver, Kidneys

Role in Jiao Ai Tang

Nourishes Yin and Blood, and cools the Blood to help contain it within the vessels. In the original formula, raw or dried Rehmannia (干地黄) is used rather than the prepared form, providing a cooling counterbalance to the warming herbs Ai Ye and Chuan Xiong, preventing the formula from becoming overly warm.
Assistants — Supports or moderates other herbs
Bai Shao

Bai Shao

White peony root

Dosage 10 - 20g
Temperature Slightly Cool
Taste Bitter (苦 kǔ), Sour (酸 suān)
Organ Affinity Liver, Spleen

Role in Jiao Ai Tang

Nourishes Blood and astringes Yin to help contain the Blood. It also softens the Liver and alleviates pain, addressing the abdominal cramping that often accompanies these bleeding conditions. In the original formula it carries the largest dosage (4 liang), reflecting its importance in both nourishing and constraining the Blood.
Chuan Xiong

Chuan Xiong

Sichuan lovage rhizome

Dosage 6 - 10g
Temperature Warm
Taste Acrid / Pungent (辛 xīn)
Organ Affinity Liver, Gallbladder, Pericardium

Role in Jiao Ai Tang

Moves Blood and Qi to prevent stasis. In a formula that otherwise focuses on nourishing and consolidating, Chuan Xiong ensures that Blood circulation remains smooth and that the nourishing, heavy herbs do not cause stagnation. It is used in a relatively small dose to move gently without aggravating bleeding.
Envoy — Directs the formula to its target
Gan Cao

Gan Cao

Licorice root

Dosage 3 - 6g
Temperature Neutral
Taste Sweet (甘 gān)
Organ Affinity Heart, Lungs, Spleen, Stomach

Role in Jiao Ai Tang

Harmonizes the actions of all the other herbs and tonifies the Spleen Qi. Since the Spleen governs the Blood and keeps it within the vessels, strengthening Spleen function supports the formula's overall hemostatic strategy. It also pairs with Bai Shao to relax spasms and relieve abdominal pain.

Why This Combination Works

How the herbs in Jiao Ai Tang complement each other

Overall strategy

The formula combines Blood-nourishing and Blood-stopping herbs with gentle channel-warming action to address both the root (Chong and Ren deficiency with Cold) and the branch (uterine bleeding). It contains the four herbs that later became Si Wu Tang (Four Substances Decoction) as its blood-nourishing backbone, layered with the signature pairing of E Jiao and Ai Ye for hemostasis and uterine warming.

King herbs

E Jiao and Ai Ye together form the core of the formula's identity and give the formula its name. E Jiao is sweet, neutral, and rich in nourishing quality: it enters the Liver, Lung, and Kidney channels to replenish Blood and Yin and directly stop bleeding through its sticky, consolidating nature. Ai Ye is warm and aromatic, entering the Liver, Spleen, and Kidney channels to warm the meridians, stop bleeding, and calm the fetus. Together they represent a balanced Yin-Yang pairing: E Jiao nourishes and consolidates, Ai Ye warms and stabilizes.

Deputy herbs

Dang Gui and Gan Di Huang strengthen the Blood-nourishing foundation. Dang Gui tonifies Blood while gently promoting circulation, ensuring the new Blood moves smoothly rather than pooling. Gan Di Huang (dried Rehmannia, used raw) enriches Blood and Yin while its cool nature balances the warming action of Ai Ye and Chuan Xiong, preventing the formula from becoming excessively warm.

Assistant herbs

Bai Shao (reinforcing assistant) nourishes and astringes Blood, and softens the Liver to relieve the cramping pain common in these conditions. Chuan Xiong (restraining assistant) is a small amount of a Blood-moving herb that prevents the rich, sticky quality of E Jiao and the heavy nourishment of Sheng Di Huang from causing Blood stasis. This is a classic application of 'stopping bleeding without retaining stasis'.

Envoy herbs

Zhi Gan Cao harmonizes all the other herbs and tonifies Spleen Qi. Since the Spleen's function of 'governing Blood' (controlling it within the vessels) is crucial to preventing abnormal bleeding, this support for the Spleen adds another layer to the formula's hemostatic strategy. It also synergizes with Bai Shao to relieve spasms and abdominal pain.

Notable synergies

The E Jiao and Ai Ye pairing is the formula's signature: one nourishes Yin and Blood from a cooling, consolidating angle, while the other warms Yang and the channels, creating a comprehensive approach to hemostasis. The four herbs Dang Gui, Bai Shao, Chuan Xiong, and Gan Di Huang together form what later became Si Wu Tang, the foundational Blood-nourishing formula. The use of rice wine (Qing Jiu) as a co-solvent warms the channels and enhances the circulation of the medicinals to the lower body, boosting the formula's ability to reach the uterus.

How to Prepare

Traditional preparation instructions for Jiao Ai Tang

Decoct all herbs except E Jiao (Ass-Hide Gelatin) in 5 cups of water mixed with 3 cups of rice wine (or cooking wine as a substitute). Bring to a boil, then simmer until the liquid reduces to approximately 3 cups. Strain out the dregs. While the strained decoction is still hot, add the E Jiao and stir until it is completely dissolved (this is called 'melting in', or yang hua 烊化). Divide into 3 doses and take warm, once in the morning, once at midday, and once in the evening. If the condition does not improve, prepare another batch.

Common Modifications

How practitioners adapt Jiao Ai Tang for specific situations

Added
Huang Qi

15-30g, strongly tonifies Qi to lift and secure the fetus

Huang Qi boosts the Spleen's ability to hold Blood in the vessels and lifts sinking Qi that may contribute to the sensation of the fetus 'bearing down'. This modification appears in the San Yin Ji Yi Bing Zheng Fang Lun for fetal restlessness with Qi collapse.

Educational content — always consult a qualified healthcare provider or TCM practitioner before using any herbal formula.

Contraindications

Situations where Jiao Ai Tang should not be used or requires extra caution

Avoid

Bleeding due to Blood Heat (Yin deficiency with Heat) — this formula is warming in nature and designed for deficiency-Cold patterns. Using it when bleeding is caused by Heat driving Blood recklessly out of the vessels will worsen the condition.

Avoid

Bleeding caused by Blood stasis (Qi stagnation and Blood stasis pattern) — the formula's strategy is to tonify and warm, not to break stasis. If uterine masses (zheng jia) or strong Blood stasis are the root cause of bleeding, this formula is inappropriate and may retain the pathological stasis.

Avoid

Excess Heat patterns with signs such as red face, bitter taste, yellow tongue coating, rapid forceful pulse, and dark red bleeding with clots. The warm nature of Ai Ye (mugwort) and the rich tonifying quality of E Jiao can trap Heat and worsen bleeding.

Caution

Spleen and Stomach deficiency with significant dampness or poor digestion — E Jiao and Shu Di Huang (or Sheng Di Huang) are heavy, cloying, and difficult to digest. In patients with marked bloating, loose stools, or heavy tongue coating, the formula should be modified with digestive herbs or used with caution.

Caution

Active acute infections or febrile illness — the tonifying and warming properties of this formula are not suitable during active febrile conditions. Treat the acute infection first before using tonifying Blood formulas.

Special Populations

Important considerations for pregnancy, breastfeeding, and pediatric use

Pregnancy

Jiao Ai Tang is one of the few classical formulas specifically designed for use during pregnancy. Its primary classical indication includes threatened miscarriage (tai lou) and 'womb obstruction' (bao zu) with vaginal bleeding and abdominal pain during pregnancy. One published RCT (Ushiroyama et al., 2006) used it successfully in 36 women with threatened abortion, showing faster uterine hemostasis compared to hCG controls. However, it must only be used when the pattern matches: Blood deficiency with Cold, presenting with pale thin blood, cold lower abdomen, pale tongue, and weak pulse. It is contraindicated during pregnancy if bleeding is caused by Blood Heat or Blood stasis, as its warming nature could worsen those conditions. Chuan Xiong (Ligusticum) has mild Blood-moving properties and its dosage should be carefully controlled in pregnancy. Use should always be supervised by a qualified practitioner with experience in obstetric applications of herbal medicine.

Breastfeeding

No specific contraindication during breastfeeding has been documented in classical or modern sources. The formula's Blood-tonifying properties (from Dang Gui, Bai Shao, Di Huang, and E Jiao) may theoretically support recovery in postpartum women who are blood-deficient. Gan Cao (licorice) is present in a moderate dose and is generally considered safe during breastfeeding at standard formula dosages. However, E Jiao (donkey-hide gelatin) and the rich Blood-nourishing herbs can be heavy on digestion, so nursing mothers with weak Spleen and Stomach function should be monitored. As with any herbal formula during breastfeeding, use should be supervised by a qualified practitioner.

Children

Jiao Ai Tang is a gynecological formula designed primarily for adult women with menstrual or pregnancy-related bleeding disorders. It is not a standard pediatric formula. In rare cases where it might be considered for adolescent girls experiencing heavy menstrual bleeding due to a confirmed Blood deficiency with Cold pattern, dosages should be significantly reduced (typically one-third to one-half of adult doses depending on age and body weight). E Jiao can be difficult for children to digest. Use in children under 12 is not recommended without specific clinical justification and supervision by an experienced practitioner.

Drug Interactions

If you are taking pharmaceutical medications, be aware of these potential interactions with Jiao Ai Tang

Anticoagulant and antiplatelet medications (e.g. warfarin, heparin, aspirin, clopidogrel): Jiao Ai Tang has demonstrated hemostatic (pro-clotting) effects in pharmacological studies, including shortened clotting time and reduced fibrinolytic activity. This directly opposes the mechanism of anticoagulant drugs. Concurrent use could reduce the effectiveness of blood-thinning medications or create unpredictable effects on coagulation. Patients on anticoagulant therapy should avoid this formula or use it only under close medical supervision with coagulation monitoring.

Hormone replacement therapy and oral contraceptives: Animal studies have shown that Jiao Ai Tang can induce estrogen receptor (ERα and ERβ) expression in uterine tissue, suggesting estrogen-like activity. This could theoretically interact with hormonal medications. Women taking estrogen-based therapies should consult their physician before using this formula.

Gan Cao (Glycyrrhiza/licorice) interactions: The Gan Cao in this formula may interact with corticosteroids (potentiating their effects), antihypertensive medications (licorice can cause sodium retention and raise blood pressure), digoxin and cardiac glycosides (licorice-induced hypokalemia increases toxicity risk), and diuretics (compounding potassium loss). These interactions are dose-dependent and more relevant with prolonged use.

Usage Guidance

Practical advice for getting the most out of Jiao Ai Tang

Best time to take

Warm, taken three times daily after meals (the classical text specifies 温服一升, 日三服 — warm dose, three times daily). Taking it after meals helps protect the Stomach from the cloying nature of E Jiao and Di Huang.

Typical duration

Typically prescribed for 1-4 weeks depending on the condition; for threatened miscarriage, used until bleeding stops and the pregnancy stabilizes; reassessed regularly by the practitioner.

Dietary advice

While taking this formula, favor warm, easily digestible, Blood-nourishing foods such as bone broth, dark leafy greens, red dates (da zao), goji berries, eggs, and well-cooked grains. These support the formula's Blood-tonifying action. Avoid cold and raw foods (salads, iced drinks, raw fruits in excess, sashimi) as they can impair Spleen function and counteract the formula's warming strategy. Also avoid greasy, heavy, or overly rich foods that may overwhelm digestion, since E Jiao and Di Huang are already cloying in nature. Spicy and hot foods should be consumed in moderation to avoid generating internal Heat. The original preparation method calls for decocting with Qing Jiu (clear rice wine), which aids the formula's Blood-moving and channel-warming action.

Jiao Ai Tang originates from Jin Gui Yao Lue (金匮要略, Essentials from the Golden Cabinet) by Zhang Zhongjing Eastern Han dynasty (东汉), circa 200 CE

Classical Texts

Key passages from the classical Chinese medical texts that first described Jiao Ai Tang and its clinical use

Jin Gui Yao Lue (金匮要略) — Zhang Zhongjing

Original text: 「师曰:妇人有漏下者,有半产后因续下血都不绝者,有妊娠下血者,假令妊娠腹中痛,为胞阻,胶艾汤主之。」

Translation: "The Master said: For women who have persistent spotting (vaginal bleeding), those who continue to bleed without stopping after a miscarriage, or those who bleed during pregnancy — if during pregnancy there is abdominal pain, this is called 'womb obstruction' (bao zu), and Jiao Ai Tang governs it."

This passage from the chapter on pregnancy disorders (妇人妊娠病脉证并治) establishes the three core indications of the formula: chronic uterine bleeding (lou xia), post-miscarriage hemorrhage, and threatened miscarriage with abdominal pain.

Jin Gui Yao Lue Xin Dian (金匮要略心典) — You Yi (尤怡)

Original text: 「妇人经水淋漓,及胎产前后下血不止者,皆冲任脉虚,而阴气不能守也。是惟胶艾汤为能补而固之。中有芎、归,能于血中行气;艾叶利阴气,止痛安胎,故亦治妊娠胞阻。」

Translation: "When a woman's menstrual blood drips persistently, or when bleeding before or after childbirth will not stop, these are all due to deficiency of the Chong and Ren vessels, with the Yin Qi unable to hold firm. Only Jiao Ai Tang can tonify and secure it. Within it, Chuan Xiong and Dang Gui can move Qi within the Blood; Ai Ye benefits Yin Qi, stops pain and calms the fetus, and therefore also treats womb obstruction during pregnancy."

Historical Context

How Jiao Ai Tang evolved over the centuries — its origins, lineage, and place in the broader tradition of Chinese medicine

Jiao Ai Tang originates from Zhang Zhongjing's Jin Gui Yao Lue (金匮要略, Essentials from the Golden Cabinet), written during the late Eastern Han dynasty around 200 CE. It appears in the chapter on women's pregnancy disorders (妇人妊娠病脉证并治). The formula is also known by its full name Xiong Gui Jiao Ai Tang (芎归胶艾汤), reflecting the prominence of Chuan Xiong (芎) and Dang Gui (归) alongside the two title herbs E Jiao (胶) and Ai Ye (艾).

The formula's core structure is essentially Si Wu Tang (Four Substances Decoction) — Dang Gui, Bai Shao, Chuan Xiong, and Di Huang — plus E Jiao, Ai Ye, and Gan Cao. This is notable because Si Wu Tang itself only became independently famous centuries later (its earliest standalone appearance is usually attributed to the Song dynasty Tai Ping Hui Min He Ji Ju Fang). Jiao Ai Tang thus represents an earlier, more complete therapeutic concept from which the simpler Si Wu Tang was later distilled. Later medical texts expanded the formula's applications: the Qian Jin Yi Fang (千金翼方) version by Sun Simiao added Gan Jiang (dried ginger) and extended the indications to traumatic hemorrhage and male bleeding disorders. The Tai Ping Hui Min He Ji Ju Fang (Song dynasty) adopted the formula for broader gynecological use including postpartum wasting. Across these historical variations, some versions use raw Rehmannia (Sheng Di Huang, as in the original Jin Gui text specifying "干地黄") while later adaptations often substituted processed Rehmannia (Shu Di Huang) for stronger Blood-tonifying effect.

The formula has been influential in Japanese Kampo medicine under the name Kyuki-kyogai-to (芎帰膠艾湯), where it continues to be used for uterine bleeding and threatened miscarriage, and has been the subject of modern clinical trials in Japan.

Modern Research

A published study investigating the pharmacological effects or clinical outcomes of Jiao Ai Tang

1

RCT: Efficacy of Xiong-gui-jiao-ai-tang in Threatened Abortion in Early Pregnancy (2006)

Ushiroyama T, Ikeda A, Sakai M, Hosotani T, Suzuki Y, Tsubokura S, Ueki M. The American Journal of Chinese Medicine, 2006, 34(5), 731-740.

A randomized controlled trial at Osaka Medical College enrolled 72 women with threatened abortion. The treatment group (36 women) received Xiong-gui-jiao-ai-tang at 7.5 g/day, while the control group received hCG injections. The herbal formula group achieved uterine hemostasis significantly faster (2.9 vs. 10.8 days, p < 0.0001) and showed faster disappearance of retroplacental hematoma (9.9 vs. 23.2 days, p < 0.0001). The study concluded the formula had beneficial effects in stabilizing early pregnancy.

DOI

Research on TCM formulas is growing but still limited by Western clinical trial standards. These studies provide emerging evidence and should be considered alongside practitioner expertise.