Wen Jing Tang

Warm the Menses Decoction · 温经汤

Also known as: Da Wen Jing Tang (大温经汤, Major Warm the Menses Decoction)

A classical gynecological formula that gently warms the channels and uterus while nourishing blood and clearing old stagnation. It is used for irregular periods, painful menstruation, prolonged spotting, and difficulty conceiving when caused by internal coldness and poor blood circulation in the lower abdomen, often accompanied by warm palms, dry lips, and evening feverishness.

Origin Jin Gui Yao Lue (金匱要略, Essentials from the Golden Cabinet) by Zhang Zhongjing — Eastern Hàn dynasty, c. 220 CE
Composition 12 herbs
Wu Zhu Yu
King
Wu Zhu Yu
Gui Zhi
King
Gui Zhi
Dang Gui
Deputy
Dang Gui
Chuan Xiong
Deputy
Chuan Xiong
Mu Dan Pi
Deputy
Mu Dan Pi
Bai Shao
Assistant
Bai Shao
E Jiao
Assistant
E Jiao
Tian Men Dong
Assistant
Tian Men Dong
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Educational content Consult qualified TCM practitioners for diagnosis and treatment

Patterns Addressed

In TCM, symptoms don't appear randomly — they cluster into recognizable patterns of disharmony that reveal what's out of balance in the body. Wen Jing Tang is designed to correct these specific patterns.

Why Wen Jing Tang addresses this pattern

This is the primary pattern addressed by Wen Jing Tang. The Chong vessel (the 'Sea of Blood') and Ren vessel (governing the uterus and reproductive function) become weakened and invaded by cold. This cold causes blood to congeal and stagnate, disrupting menstruation, causing pain, and potentially preventing conception. The formula warms the Chong and Ren with Wu Zhu Yu and Gui Zhi, moves the stagnant blood with Dang Gui, Chuan Xiong, and Mu Dan Pi, and replenishes blood with E Jiao, Bai Shao, and Dang Gui. Meanwhile, Ren Shen and Gan Cao support the Spleen to generate new blood, and Mai Men Dong with E Jiao address the secondary Yin depletion that develops from chronic blood loss and stasis.

A practitioner would look for one or more of these signs

Irregular Menstruation

Periods early, late, prolonged, or absent

Menstrual Cramps

Lower abdominal cold pain improved by warmth

Bleeding

Dark blood with clots, or prolonged spotting (lou xia)

Infertility

Due to cold uterus (gong han)

Dry Lips

Lips and mouth dry, a key diagnostic indicator

Hot Palms And Soles

Warm or irritable palms, especially in the evening

Fever

Low-grade fever worsening toward dusk

Abdominal Distention

Lower abdominal fullness and urgency (li ji)

Commonly Prescribed For

These conditions can arise from the patterns above. A practitioner would consider Wen Jing Tang when these conditions are specifically caused by those patterns — not for all cases of these conditions.

Arises from: Chong and Ren Deficiency Cold with Blood Stasis Blood Deficiency

TCM Interpretation

In TCM, conception depends on a warm, well-nourished uterus with free-flowing blood in the Chong and Ren vessels. When these vessels are weakened by constitutional deficiency or past events like miscarriage, cold can settle in the lower abdomen and cause blood to stagnate. This creates a 'cold womb' (gong han) where the uterine environment is too cold and stagnant for a fertilized egg to implant and thrive. The Kidney and Liver systems, which govern reproduction and blood storage respectively, are both impaired. The Spleen, which generates the Qi and blood needed to nourish the uterine lining, may also be insufficient.

Why Wen Jing Tang Helps

Wen Jing Tang directly warms the uterus through Wu Zhu Yu and Gui Zhi, restoring the warmth needed for healthy reproductive function. Dang Gui and Chuan Xiong invigorate blood circulation to the pelvic organs, helping clear old stasis that blocks implantation. E Jiao and Bai Shao nourish blood to build a healthier uterine lining, while Ren Shen supports the Spleen to ensure ongoing production of Qi and blood. Modern research suggests this formula may promote ovulation and improve uterine blood flow, and has been shown to enhance the effectiveness of fertility treatments. The formula's balanced approach of simultaneously warming, moving, and nourishing makes it particularly well-suited for the complex, mixed-deficiency pattern commonly seen in infertility.

Also commonly used for

Irregular Menstruation

Due to Chong-Ren deficiency cold and blood stasis

Bleeding

Dysfunctional uterine bleeding, metrorrhagia

Endometriosis

When pattern matches Chong-Ren cold with stasis

Chronic Pelvic Inflammatory Disease

Chronic pelvic inflammation with cold signs

Polycystic Ovary Syndrome

When accompanied by cold uterus and menstrual irregularity

Miscarriage

Recurrent pregnancy loss related to cold uterine environment

What This Formula Does

Every TCM formula has a specific set of actions — here's what Wen Jing Tang does in the body, explained in both everyday and TCM terms

Therapeutic focus

In practical terms, Wen Jing Tang is primarily used to support these areas of health:

TCM Actions

In TCM terminology, these are the specific therapeutic actions that Wen Jing Tang performs to restore balance in the body:

How It Addresses the Root Cause

TCM doesn't just suppress symptoms — it aims to resolve the underlying imbalance. Here's how Wen Jing Tang works at the root level.

Wen Jing Tang addresses a complex condition where deficiency, Cold, Blood stasis, and mild Heat all coexist in the body, with the Chong Mai (Penetrating Vessel) and Ren Mai (Conception Vessel) as the primary sites of dysfunction. These two extraordinary vessels govern menstruation, fertility, and reproductive function in women.

The root of the problem is deficiency of both Qi and Blood in the Chong and Ren vessels. This may develop from constitutional weakness, aging (particularly around menopause when the body's reproductive vitality naturally declines), repeated pregnancies or miscarriages, prolonged illness, or chronic blood loss. When Qi and Blood become insufficient, the body loses its capacity to keep the vessels and uterus warm. Cold then accumulates internally, either from this Yang deficiency or from external Cold invading the uterus. Cold causes Blood to congeal and stagnate, just as water freezes in winter. This stagnant Blood obstructs the uterus and lower abdomen, preventing menstrual Blood from flowing smoothly and blocking the normal nourishment needed for conception.

The stagnation creates a vicious cycle: old Blood cannot leave, new Blood cannot be generated, and the uterus remains cold and poorly nourished. Meanwhile, the Blood stasis and Yin-Blood deficiency produce a secondary "false Heat" that floats upward and outward. This explains the characteristic pattern of Cold signs below (cold lower abdomen, congealed menstrual blood) coexisting with apparent Heat signs above (evening fever, hot palms, dry lips). The lip and mouth dryness is not from true Heat consuming fluids but rather from Blood stasis preventing fluids and nourishment from reaching the upper body. The formula works because it simultaneously warms the channels to disperse Cold, moves Blood to resolve stasis, nourishes Blood and Yin to address the underlying deficiency, and gently clears the secondary deficiency Heat, thereby restoring the Chong and Ren vessels to their normal function of governing menstruation and fertility.

Formula Properties

Every formula has an inherent temperature, taste, and affinity for specific organs — these properties determine how it interacts with the body

Overall Temperature

Warm

Taste Profile

Predominantly pungent and sweet with some bitterness. Pungent to warm the channels and move Blood, sweet to tonify Qi and nourish Blood, and mildly bitter to clear deficiency Heat.

Channels Entered

Liver Spleen Kidney Stomach Chong Mai (冲脉) Penetrating Vessel Ren Mai (任脉) Conception Vessel

Ingredients

12 herbs

The herbs that make up Wen Jing Tang, organized by their role in the prescription

King — Main ingredient driving the formula
Deputy — Assists and enhances the King
Assistant — Supports or moderates other herbs
Envoy — Directs the formula to its target
Kings — Main ingredient driving the formula
Wu Zhu Yu

Wu Zhu Yu

Evodia fruit

Dosage 6 - 9g
Temperature Hot
Taste Acrid / Pungent (辛 xīn), Bitter (苦 kǔ)
Organ Affinity Liver, Spleen, Stomach, Kidneys

Role in Wen Jing Tang

The chief warming herb of the formula. Wu Zhu Yu is acrid and hot, entering the Liver and Stomach channels. It excels at dispersing cold from the lower abdomen and Chong-Ren vessels, relieving pain, and warming the uterus. Its relatively high dose in the original formula underscores its primary role in addressing the root cause of cold obstruction.
Gui Zhi

Gui Zhi

Cinnamon twig

Dosage 6 - 9g
Temperature Warm
Taste Acrid / Pungent (辛 xīn), Sweet (甘 gān)
Organ Affinity Heart, Lungs, Urinary Bladder

Role in Wen Jing Tang

Warms the channels and promotes the flow of blood through the vessels. Gui Zhi works alongside Wu Zhu Yu to break through cold obstruction in the blood vessels, particularly those serving the uterus and lower abdomen. It is warm rather than hot, contributing a gentle, penetrating warmth.
Deputies — Assists and enhances the King
Dang Gui

Dang Gui

Chinese Angelica root

Dosage 6 - 9g
Temperature Warm
Taste Sweet (甘 gān), Acrid / Pungent (辛 xīn)
Organ Affinity Liver, Heart, Spleen

Role in Wen Jing Tang

Nourishes blood and invigorates blood circulation to regulate menstruation. It works with Chuan Xiong to move stagnant blood while simultaneously replenishing blood that has been lost through irregular bleeding.
Chuan Xiong

Chuan Xiong

Sichuan lovage rhizome

Dosage 6 - 9g
Temperature Warm
Taste Acrid / Pungent (辛 xīn)
Organ Affinity Liver, Gallbladder, Pericardium

Role in Wen Jing Tang

Known as the 'Qi herb within the blood,' Chuan Xiong moves blood vigorously and dispels stasis. It activates circulation in the Chong and Ren vessels and reinforces the blood-moving actions of Dang Gui.
Mu Dan Pi

Mu Dan Pi

Tree peony root bark

Dosage 6 - 9g
Temperature Slightly Cool
Taste Bitter (苦 kǔ), Acrid / Pungent (辛 xīn)
Organ Affinity Heart, Liver, Kidneys

Role in Wen Jing Tang

Serves a dual function: it assists the blood-moving herbs in dispersing stasis, while also cooling heat in the blood layer. This addresses the secondary virtual heat symptoms (evening fever, warm palms) that arise from depleted Yin blood.
Assistants — Supports or moderates other herbs
Bai Shao

Bai Shao

White peony root

Dosage 6 - 9g
Temperature Slightly Cool
Taste Bitter (苦 kǔ), Sour (酸 suān)
Organ Affinity Liver, Spleen

Role in Wen Jing Tang

Nourishes blood and restrains Yin, softens the Liver, and relieves cramping pain. Its cool, astringent nature helps balance the warming herbs and supports the blood-nourishing strategy.
E Jiao

E Jiao

Donkey-hide gelatin

Dosage 6 - 9g
Temperature Neutral
Taste Sweet (甘 gān)
Organ Affinity Lungs, Liver, Kidneys
Preparation Dissolve separately into the strained decoction (烊化, yang hua). Do not boil with the other herbs.

Role in Wen Jing Tang

Nourishes blood, stops bleeding, and moistens dryness. Particularly important for addressing the lip dryness and blood deficiency seen in this pattern, and for controlling excessive uterine bleeding. It also provides Yin-nourishing moisture to counterbalance the warm, drying King herbs.
Tian Men Dong

Tian Men Dong

Asparagus tuber

Dosage 9 - 15g
Temperature Cold
Taste Sweet (甘 gān), Bitter (苦 kǔ)
Organ Affinity Lungs, Kidneys

Role in Wen Jing Tang

Nourishes Yin and clears deficiency heat, generating fluids to address dry lips and mouth. Together with E Jiao and Bai Shao, it restrains the warm-drying tendency of Wu Zhu Yu and Gui Zhi, creating the formula's characteristic balance between warming and nourishing.
Ren Shen

Ren Shen

Ginseng root

Dosage 6 - 9g
Temperature Slightly Warm
Taste Sweet (甘 gān), Bitter (苦 kǔ)
Organ Affinity Spleen, Lungs, Heart, Kidneys

Role in Wen Jing Tang

Strengthens the Spleen and tonifies Qi to support blood production. Since blood is generated from Qi, supplementing the Spleen ensures a sustainable source of new blood to replace what has been lost.
Ban Xia

Ban Xia

Pinellia rhizome

Dosage 6 - 9g
Temperature Warm
Taste Acrid / Pungent (辛 xīn)
Organ Affinity Spleen, Stomach, Lungs

Role in Wen Jing Tang

Descends counterflow Qi, harmonizes the Stomach, and disperses accumulations. It helps the Stomach Qi descend smoothly, which supports the overall movement of Qi and blood. It also assists in opening up channels blocked by stagnation.
Sheng Jiang

Sheng Jiang

Fresh ginger rhizome

Dosage 6 - 9g
Temperature Slightly Warm
Taste Acrid / Pungent (辛 xīn)
Organ Affinity Lungs, Spleen, Stomach

Role in Wen Jing Tang

Warms the Stomach and supports digestion, assists Wu Zhu Yu and Gui Zhi in dispersing cold, and harmonizes the digestive system to optimize absorption of the other herbs.
Envoy — Directs the formula to its target
Gan Cao

Gan Cao

Licorice root

Dosage 6 - 9g
Temperature Neutral
Taste Sweet (甘 gān)
Organ Affinity Heart, Lungs, Spleen, Stomach

Role in Wen Jing Tang

Tonifies the Spleen and harmonizes all the herbs in the formula. Moderates the harsh properties of the other medicinals and ensures they work together smoothly.

Why This Combination Works

How the herbs in Wen Jing Tang complement each other

Overall strategy

Wen Jing Tang addresses a complex condition where cold, blood stasis, blood deficiency, and secondary deficiency heat coexist in the Chong and Ren vessels. The formula's genius lies in simultaneously warming the channels to dispel cold, moving blood to clear stasis, nourishing blood and Yin to address deficiency, and gently clearing the virtual heat that arises from depleted Yin blood.

King herbs

Wu Zhu Yu (Evodia) and Gui Zhi (Cinnamon Twig) form the warming core of the formula. Wu Zhu Yu, the highest-dosed herb in the original text, enters the Liver channel and powerfully disperses cold from the lower abdomen and uterus while relieving pain. Gui Zhi warms and unblocks the blood vessels throughout the channels. Together, they restore warmth and circulation to the Chong and Ren vessels, directly addressing the root pathology of cold obstruction.

Deputy herbs

Dang Gui (Chinese Angelica), Chuan Xiong (Sichuan Lovage Root), and Mu Dan Pi (Moutan Bark) reinforce the Kings by targeting the blood stasis component. Dang Gui and Chuan Xiong are the classical pair for nourishing and moving blood to regulate menstruation. Mu Dan Pi adds a unique dual action: it helps dispel blood stasis while simultaneously cooling heat in the blood layer, which addresses the evening fever and warm palms that signal deficiency heat.

Assistant herbs

Nourishing group (restraining assistants): E Jiao (Ass-Hide Gelatin), Bai Shao (White Peony), and Mai Men Dong (Ophiopogon) form a crucial counterbalance to the warm King herbs. E Jiao nourishes blood, stops bleeding, and moistens dryness. Bai Shao nourishes and astringes blood while softening the Liver and easing cramping. Mai Men Dong generates fluids and clears deficiency heat. These three prevent the warming herbs from consuming Yin and blood, and directly address symptoms like dry lips and warm palms.

Qi-supporting group (reinforcing assistants): Ren Shen (Ginseng) strengthens the Spleen and tonifies Qi, ensuring that the body can generate new blood from its digestive function. This is essential because blood deficiency cannot be resolved without adequate Qi.

Harmonizing group (reinforcing assistants): Ban Xia (Pinellia) and Sheng Jiang (Fresh Ginger) descend counterflow Qi, warm the Stomach, and support digestion. They ensure that the rich, blood-nourishing herbs are properly absorbed and that Stomach Qi flows downward smoothly. Sheng Jiang also adds gentle warmth to assist the King herbs.

Envoy herb

Gan Cao (Licorice Root) harmonizes the entire formula, moderating the interactions between the warming, blood-moving, and Yin-nourishing ingredients. It also supports the Spleen alongside Ren Shen.

Notable synergies

The pairing of Wu Zhu Yu with Gui Zhi creates a targeted channel-warming effect greater than either alone: Wu Zhu Yu focuses warmth on the Liver channel and lower abdomen, while Gui Zhi spreads warmth through the blood vessels more broadly. The combination of Dang Gui and Chuan Xiong is the classical blood-regulating pair, moving stasis while generating new blood. The trio of E Jiao, Bai Shao, and Mai Men Dong restrains the entire warming strategy, making the formula "warm like spring" rather than "hot like summer," as the classical commentator Liu Duzou noted. Scholars have observed that the formula embeds elements of several other well-known formulas (Wu Zhu Yu Tang, Jiao Ai Tang, Mai Men Dong Tang, and Gui Zhi Tang), creating a multi-layered therapeutic effect that addresses the complex interplay of cold, stasis, deficiency, and heat simultaneously.

How to Prepare

Traditional preparation instructions for Wen Jing Tang

Combine all twelve herbs (except E Jiao) with approximately 2 litres of water. Bring to a boil, then reduce heat and simmer until the liquid is reduced to approximately 600 ml. Strain the decoction. Dissolve the E Jiao (Ass-Hide Gelatin) separately into the hot, strained liquid by stirring until fully melted (a method called yang hua, 烊化). Divide into three equal portions and take warm, one portion three times daily.

Common Modifications

How practitioners adapt Wen Jing Tang for specific situations

Added
Ai Ye

6-9g, warms the uterus and stops bleeding

Xiao Hui Xiang

3-6g, warms the lower abdomen and disperses cold

Removed
Mu Dan Pi

Its cooling nature counteracts the intensified warming strategy

Tian Men Dong

Removed to avoid dampening the cold-dispersing action

Ai Ye and Xiao Hui Xiang strengthen the cold-dispersing power when severe cold pain dominates. Removing the cooling Mu Dan Pi and moistening Mai Men Dong allows the warming action to be more direct and powerful.

Educational content — always consult a qualified healthcare provider or TCM practitioner before using any herbal formula.

Contraindications

Situations where Wen Jing Tang should not be used or requires extra caution

Avoid

Pregnancy. The formula contains Blood-moving herbs (Chuan Xiong, Dan Pi, Gui Zhi) and Wu Zhu Yu that may stimulate uterine activity. Use is contraindicated during confirmed pregnancy.

Avoid

Menstrual bleeding that is heavy with bright red or deep crimson, thick, sticky blood, indicating excess Heat or Heat in the Blood. The warming herbs in this formula may worsen such conditions.

Caution

Yin deficiency with strong internal Heat (marked by severe night sweats, strong hot flushes, red tongue with no coating). The warming components may aggravate Yin-deficient Heat if it predominates over Cold.

Caution

Robust, full-bodied constitution with a flushed complexion. This formula is designed for deficient, thin, pale individuals and is not suitable for those with a constitutionally warm or excess presentation.

Caution

Active bleeding disorders or patients on anticoagulant therapy. The Blood-moving herbs in this formula may increase bleeding tendency.

Caution

Uterine fibroids or breast lumps with signs of Heat. Use with caution, as the warming and Blood-moving properties may be inappropriate for these conditions when Heat signs predominate.

Special Populations

Important considerations for pregnancy, breastfeeding, and pediatric use

Pregnancy

Contraindicated in pregnancy. The formula contains several herbs that actively move Blood and may stimulate uterine contractions. Wu Zhu Yu (Evodia) is warming and descending, Chuan Xiong (Ligusticum) and Mu Dan Pi (Moutan Bark) are Blood-invigorating herbs with known effects on uterine smooth muscle, and Gui Zhi (Cinnamon Twig) promotes Blood circulation. Ban Xia (Pinellia) is also traditionally classified as contraindicated or cautioned in pregnancy. While Wen Jing Tang is used historically to promote fertility and help women conceive, once pregnancy is confirmed the formula should be discontinued unless a qualified practitioner makes a specific judgment otherwise.

Breastfeeding

Use with caution during breastfeeding. While the formula does not contain strongly toxic herbs, several of its ingredients are warming and Blood-moving, and their components may transfer into breast milk. Wu Zhu Yu (Evodia) has a strong pungent, bitter taste and warming nature that could theoretically affect the infant. Ban Xia (Pinellia) in its raw form is toxic, though it is always used in processed form (Zhi Ban Xia) in this formula, reducing risk. There is no strong evidence of harm during breastfeeding, but given the lack of formal safety data, use should be supervised by a qualified practitioner and is best reserved for clear clinical need.

Children

Wen Jing Tang is a gynecological formula specifically designed for menstrual and reproductive disorders. It is not typically prescribed for children. In adolescent girls who have reached menarche and present with the appropriate pattern of Cold-type menstrual irregularity (scanty periods, dark blood with clots, cold lower abdomen), a practitioner may consider a significantly reduced dose under close supervision. The formula's warming and Blood-moving properties require careful assessment in younger patients whose reproductive systems are still maturing. Dosages would generally be reduced to 1/3 to 1/2 of the adult dose for teenagers, with treatment duration kept as short as clinically necessary.

Drug Interactions

If you are taking pharmaceutical medications, be aware of these potential interactions with Wen Jing Tang

Anticoagulants and antiplatelet drugs (warfarin, heparin, aspirin, clopidogrel): The Blood-moving herbs in this formula, particularly Dang Gui (Angelica sinensis), Chuan Xiong (Ligusticum), and Mu Dan Pi (Moutan bark), have known effects on platelet aggregation and blood viscosity. Concurrent use may increase bleeding risk. INR monitoring is advisable if the formula is used alongside warfarin.

Hormonal medications (oral contraceptives, hormone replacement therapy, clomiphene): Research shows that Wen Jing Tang affects the hypothalamic-pituitary-ovarian axis, modulating estradiol, FSH, and LH levels. Concurrent use with hormonal therapies may produce unpredictable interactions. While some studies have combined it with clomiphene with positive results, this should only be done under professional supervision.

Gan Cao (Glycyrrhiza/Licorice) in this formula may interact with corticosteroids (potentiating their effects), digoxin and other cardiac glycosides (via potassium depletion), diuretics (compounding potassium loss), and antihypertensive medications (licorice can cause sodium retention and raise blood pressure). These interactions are dose-dependent and are more relevant with long-term use.

Ban Xia (Pinellia) may theoretically interact with sedative or anti-nausea medications due to overlapping effects on the central nervous system and gastrointestinal motility.

Usage Guidance

Practical advice for getting the most out of Wen Jing Tang

Best time to take

Warm, divided into 2-3 doses per day, taken 30-60 minutes after meals to reduce potential stomach irritation from Wu Zhu Yu and Ban Xia.

Typical duration

Usually taken for 2-3 menstrual cycles (roughly 2-3 months), then reassessed. May be extended to 3-6 months for infertility or chronic conditions, with periodic review.

Dietary advice

While taking this formula, favor warm, cooked, easily digestible foods. Nourishing foods rich in protein and collagen are beneficial, such as slow-cooked bone broth, stewed chicken, lamb, eggs, red dates, and goji berries. Foods that warm the middle and support Blood production are ideal. Avoid cold and raw foods (salads, sushi, iced drinks, ice cream), as these counteract the formula's warming action. Also avoid greasy, heavily fried foods that may impair digestion and obstruct the Spleen's ability to generate Blood. Limit spicy, hot foods and alcohol, which could aggravate the deficiency Heat component of the pattern. Smoking should be avoided as it constricts blood vessels and impairs circulation.

Wen Jing Tang originates from Jin Gui Yao Lue (金匱要略, Essentials from the Golden Cabinet) by Zhang Zhongjing Eastern Hàn dynasty, c. 220 CE

Classical Texts

Key passages from the classical Chinese medical texts that first described Wen Jing Tang and its clinical use

Jin Gui Yao Lue (《金匮要略》), Chapter 22: Miscellaneous Gynecological Diseases

「问曰:妇人年五十所,病下利数十日不止,暮即发热,少腹里急,腹满,手掌烦热,唇口干燥,何也?师曰:此病属带下。何以故?曾经半产,瘀血在少腹不去。何以知之?其证唇口干燥,故知之。当以温经汤主之。」

Question: A woman of about fifty has had persistent vaginal discharge [or bleeding] for several tens of days. In the evenings she develops fever. She has urgency and tightness in the lower abdomen, abdominal fullness, hot and irritable palms, and dry lips and mouth. What is this? The Master says: This illness belongs to the category of gynecological disease. Why? She has previously had a miscarriage, and stagnant Blood remains in the lower abdomen. How can this be known? From the sign of dry lips and mouth. Wen Jing Tang governs this.

「亦主妇人少腹寒,久不受胎;兼取崩中去血,或月水来过多,及至期不来。」

It also governs women with Cold in the lower abdomen and prolonged inability to conceive; and additionally treats uterine flooding with excessive bleeding, or menstrual flow that is too heavy, or periods that fail to arrive.


Yi Zong Jin Jian (《医宗金鉴》) commentary:

「此皆曾经半产崩中,新血难生,瘀血未尽,风寒客于胞中,为带下,为崩中,为经水愆期,为胞寒不孕。均用温经汤主之者,以此方生新去瘀,暖子宫补冲任也。」

All of these arise from previous miscarriage or flooding, where new Blood is difficult to generate and old stagnant Blood has not been fully cleared, and Cold has lodged in the uterus. This gives rise to vaginal discharge, flooding, irregular periods, and uterine Cold infertility. Wen Jing Tang is used to govern all of these because this formula generates new Blood while removing stasis, warms the uterus, and supplements the Chong and Ren vessels.

Historical Context

How Wen Jing Tang evolved over the centuries — its origins, lineage, and place in the broader tradition of Chinese medicine

Wen Jing Tang originates from the Jin Gui Yao Lue (Synopsis of Prescriptions of the Golden Chamber), compiled by Zhang Zhongjing during the late Eastern Han dynasty (around 200 CE). It is one of the most celebrated gynecological formulas in the Chinese medical tradition, often called the "ancestor formula for regulating menstruation" (调经之祖方). The original case presented in the text describes a woman of about fifty suffering from prolonged bleeding, evening fevers, abdominal discomfort, hot palms, and dry lips following a prior miscarriage, representing a complex interweaving of deficiency, Cold, and Blood stasis.

A separate formula also called Wen Jing Tang appears in Chen Ziming's Fu Ren Da Quan Liang Fang (Complete Collection of Good Formulas for Women, Song dynasty). That version uses different herbs including Mozhao (Curcuma/Ezhu) and Niu Xi (Achyranthes) and is stronger in its Blood-moving action, while the Jin Gui version emphasizes nourishing and warming. The two formulas share a name and general therapeutic direction but are distinct prescriptions for somewhat different clinical presentations.

The Qing dynasty physician Chen Xiuyuan famously praised the Jin Gui version, writing that "regardless of Yin or Yang, deficiency or excess, amenorrhea or flooding, old or young, when skillfully applied it brings results without fail," elevating it almost to the status of a secret formula. The eminent modern scholar Liu Duzhou emphasized that the word "Wen" (温) in the formula name should be understood not as "hot" but as "harmoniously warm" (和), comparing its gentle balancing effect to the mild warmth of springtime rather than the fierce heat of summer. In Japan, the formula is known as Unkei-to and has been extensively studied in the Kampo tradition, particularly for ovulatory disorders and PCOS, with researchers discovering its effects on the hypothalamic-pituitary-ovarian axis.

Modern Research

4 published studies investigating the pharmacological effects or clinical outcomes of Wen Jing Tang

1

Systematic Review and Meta-Analysis: Clinical Efficacy of Wenjing Decoction in the Treatment of Ovulatory Disorder Infertility (2022)

Zuo QQ, Yu ZF, Liu MR, Du HL. Medicine. 2022;101(28):e29640.

This systematic review analyzed 11 randomized controlled trials involving 915 women with ovulatory disorder infertility. The meta-analysis found that Wen Jing Tang was superior to clomiphene alone in terms of clinical effectiveness, pregnancy rate, ovulation rate, endometrial thickness, and dominant follicle diameter. Estradiol levels were significantly higher in the herbal medicine group, while FSH and LH levels were lower compared to the clomiphene group.

PubMed
2

RCT: Effects of Switching to Wen-Jing-Tang (Unkei-to) on Endocrinological Status and Ovulatory Induction in Women with PCOS (2006)

Ushiroyama T, Hosotani T, Mori K, Yamashita Y, Ikeda A, Ueki M. The American Journal of Chinese Medicine. 2006;34(2):177-187.

This randomized trial enrolled 64 anovulatory women with PCOS. Patients who failed initial Kampo therapy were switched to Wen Jing Tang for 8 weeks. Plasma LH levels decreased by 49-58%, and the ovulation rate in the switching group was significantly higher (59.3%) than in the continuation group. The study concluded that Wen Jing Tang effectively improves endocrine conditions in PCOS across various constitutional types.

3

Clinical Study: Combined Therapy with Wen-Jing-Tang and Clomiphene Citrate in Anovulatory Women (1989)

Yoshimoto Y, Miyake A, Tasaka K, Aono T, Tanizawa O. The American Journal of Chinese Medicine. 1989;17(3-4):243-244.

This early study tested the combination of Wen Jing Tang and clomiphene citrate in 16 infertile patients who had failed to respond to clomiphene alone. Ovulation occurred in 43.8% of patients and 48.6% of treatment cycles, with no cases of ovarian hyperstimulation syndrome. The authors suggested this combination should be tried before escalating to gonadotropin therapy.

4

Network Pharmacology Study: Mechanism of Wen Jing Tang in the Treatment of Endometriosis (2024)

Hu X, Guo X, Wei D, Yue J, Zhang J, Wang B. Heliyon. 2024;10(20):e39292.

This study used network pharmacology, molecular docking, and experimental validation to investigate how Wen Jing Tang exerts therapeutic effects against endometriosis. The research identified key active components, molecular targets, and signaling pathways, providing a molecular basis for the formula's traditional use in treating endometriosis-related dysmenorrhea and infertility.

Research on TCM formulas is growing but still limited by Western clinical trial standards. These studies provide emerging evidence and should be considered alongside practitioner expertise.