Formula

Sang Ju Yin

Mulberry Leaf & Chrysanthemum Combination | 桑菊饮

Also known as:

Morus and Chrysanthemum Combination , Morus and Chrysanthemum Tea , Morus and Chrysanthemum Drink

Properties

Exterior-releasing formulas · Cool

Key Ingredients

Sang Ye, Ju Hua

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

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About This Formula

Traditional Chinese Medicine background and properties

Formula Description

A gentle, cooling formula used for early-stage colds and respiratory infections marked by cough as the main symptom, with mild fever, slight thirst, and a floating rapid pulse. It gently clears Wind-Heat from the Lungs and restores their natural ability to regulate breathing and stop coughing.

Formula Category

Main Actions

  • Disperses Wind-Heat
  • Clears Lung Heat
  • Restores Lung Diffusing and Descending Functions
  • Stops Cough
  • Generates Fluids

TCM Patterns

In TCM, symptoms don't appear randomly — they cluster into recognizable patterns of disharmony that reveal what's out of balance in the body. Sang Ju Yin is traditionally associated with these specific patterns.

The following describes this formula's classification within Traditional Chinese Medicine theory and is provided for educational purposes only.

Why Sang Ju Yin addresses this pattern

This is the primary pattern addressed by Sang Ju Yin. Wind-Heat enters the body through the nose and mouth, lodging in the Lung's network vessels and disrupting its descending and disseminating functions. The Lung's failure to properly direct Qi downward produces cough as the main symptom. Because the invasion is still at an early, superficial stage, the Heat is mild: the fever is slight, the thirst is only mild, and the tongue coat remains thin and white. Sang Ye and Ju Hua directly scatter Wind-Heat from the Lung network vessels, while Bo He assists the release of the pathogen outward through the exterior. Xing Ren and Jie Geng restore the Lung's up-and-down Qi movement to stop the cough. Lian Qiao clears residual Heat and toxins, and Lu Gen replenishes the fluids that early-stage Heat has begun to consume. The formula's intentionally light dosage makes it perfectly calibrated for this mild stage of Wind-Heat, avoiding the risk of over-chilling and damaging the body's Qi.

A practitioner would look for one or more of these signs

Hypochondrial Pain That Is Worse On Coughing And Breathing

Dominant symptom; may be dry or with scant thin white or slightly yellow phlegm

Fever

Mild or low-grade; the patient may not feel significantly hot

Thirst

Slight thirst (微渴), indicating early fluid consumption by Heat

Sore Throat

Mild scratchy or slightly sore throat

Headaches

Mild headache from Wind-Heat rising to the head

Red Eyes

Possible redness or discomfort of the eyes from Wind-Heat affecting the upper body

How It Addresses the Root Cause

Sang Ju Yin addresses the earliest and mildest stage of a warm-pathogen invasion of the Lungs. In TCM, warm (Heat-type) pathogens enter the body through the nose and mouth and, as the classical teaching states, "first attack the Lungs." When Wind-Heat settles in the upper body, it disrupts the Lung's two essential functions: dispersing Qi outward and downward (called the Lung's "dispersing and descending"). When dispersing fails, Qi stagnates in the chest, producing cough. Because the invasion is still superficial, the body mounts only a mild defensive response, so fever is low-grade or even absent, and only slight thirst appears (indicating that Heat has just barely begun to damage fluids).

The key diagnostic picture is cough as the dominant symptom, with mild or no fever, slight thirst, a thin white tongue coating, and a floating, rapid pulse. Wu Jutong described the mechanism precisely: "Cough means Heat is injuring the Lung network vessels; the body is not very hot because the illness is not severe; thirst is slight because the Heat is not intense." The pathology sits between the exterior (the body's surface defense layer) and the Lung organ itself, in what Wu Jutong termed the "Lung network" (肺络). This is lighter than a full Defensive-level (Wei) pattern (which Yin Qiao San addresses) but already involves functional impairment of the Lung.

If this mild condition is wrongly treated with warming, acrid herbs (as was common with Xing Su San in Wu Jutong's era), the Heat is not cleared and the Lung's precious fluids are "scorched," potentially leading to chronic cough or even consumptive wasting. The formula's design reflects the Wen Bing principle of "treating the Upper Burner like a feather — only light [medicines] can lift it" (治上焦如羽,非轻不举), using gentle, cool, and light ingredients rather than heavy or harsh ones.

Formula Properties

Temperature

Cool

Taste Profile

Predominantly acrid (pungent) and slightly sweet with a mild bitter note — acrid to disperse Wind-Heat, sweet to gently moisten and protect fluids, bitter to descend and settle Lung Qi.

Target Organs
Lungs Liver
Channels Entered
Lung Liver

Formula Origin

Wēn Bìng Tiáo Biàn (温病条辨, Systematic Differentiation of Warm Diseases) by Wú Jūtōng (吴鞠通)

This is just partial information on the formula's TCM properties. More detailed information is available on the formula's dedicated page

Ingredients in Sang Ju Yin

Detailed information about each herb in Sang Ju Yin and their roles

Kings
Deputies
Assistants
Envoys
Sang Ye
Sang Ye

Mulberry leaf

Dosage: 7.5g

Temperature Cold
Taste Sweet (甘 gān), Bitter (苦 kǔ)
Organ Affinity Lungs, Liver
Parts Used Leaf (叶 yè)
Role in Sang Ju Yin

Sweet, bitter, and cool in nature, Sang Ye is the primary herb in this formula. It excels at dispersing Wind-Heat from the upper body, particularly from the Lung network vessels (肺络). It clears Lung Heat and stops coughing, directly addressing the core symptom of this pattern.

Ju Hua
Ju Hua

Chrysanthemum flower

Dosage: 3g

Temperature Slightly Cool
Taste Sweet (甘 gān), Bitter (苦 kǔ)
Organ Affinity Lungs, Liver
Parts Used Flower (花 huā)
Role in Sang Ju Yin

Pungent, sweet, and slightly cold, Ju Hua disperses Wind-Heat from the upper burner, clears the head and eyes, and assists the Lungs in their descending function. Working together with Sang Ye, the two herbs are light, aromatic, and upward-moving, forming a synergistic pair that excels at scattering Wind-Heat from the Lungs. The yellow variety (huang ju hua) is traditionally preferred for this formula due to its stronger exterior-releasing action.

Bo He
Bo He

Peppermint herb

Dosage: 2.5g

Temperature Cool
Taste Acrid / Pungent (辛 xīn), Aromatic (芳香 fāng xiāng)
Organ Affinity Lungs, Liver
Parts Used Whole plant / Aerial parts (全草 quán cǎo)
Role in Sang Ju Yin

Pungent and cool, Bo He reinforces the ability of the King herbs to disperse Wind-Heat from the exterior and the upper body. It also benefits the head, eyes, and throat, helping to release the pathogen outward through the skin.

Xing Ren
Xing Ren

Bitter apricot kernel

Dosage: 6g

Temperature Slightly Warm
Taste Bitter (苦 kǔ)
Organ Affinity Lungs, Large Intestine
Parts Used Seed (种子 zhǒng zǐ / 子 zǐ / 仁 rén)
Role in Sang Ju Yin

Bitter and slightly warm, Xing Ren descends Lung Qi. When paired with Jie Geng, the two form a classic combination: one opens the Lungs upward while the other directs Qi downward. This restores the Lung's natural rising-and-descending rhythm, which is the key mechanism for stopping cough.

Jie Geng
Jie Geng

Balloon flower root

Dosage: 6g

Temperature Neutral
Taste Bitter (苦 kǔ), Acrid / Pungent (辛 xīn)
Organ Affinity Lungs
Parts Used Root (根 gēn)
Role in Sang Ju Yin

Bitter and pungent, Jie Geng opens and lifts Lung Qi, promoting the Lung's disseminating function. Paired with Xing Ren, the one-up-one-down combination restores the Lung's normal Qi movement and relieves cough. It also guides the other herbs upward to the upper body where the pathogen resides.

Lian Qiao
Lian Qiao

Forsythia fruit

Dosage: 5g

Temperature Slightly Cool
Taste Bitter (苦 kǔ)
Organ Affinity Lungs, Heart, Small Intestine
Parts Used Fruit (果 guǒ / 果实 guǒ shí)
Role in Sang Ju Yin

Bitter and slightly cold, Lian Qiao clears Heat and resolves toxins from the upper burner. It also has a mild exterior-releasing quality that helps vent the pathogen outward, reinforcing the formula's overall Wind-Heat dispersing action.

Lu Gen
Lu Gen

Reed rhizome

Dosage: 6g

Temperature Cold
Taste Sweet (甘 gān)
Organ Affinity Lungs, Stomach
Parts Used Rhizome (根茎 gēn jīng)
Role in Sang Ju Yin

Sweet and cold, Lu Gen clears Heat and generates body fluids. It addresses the mild thirst that accompanies this pattern, where early-stage Heat has begun to slightly damage the Lung's fluids. Its gentle moistening quality prevents the formula from being too drying.

Gan Cao
Gan Cao

Licorice root

Dosage: 2.5g

Temperature Neutral
Taste Sweet (甘 gān)
Organ Affinity Heart, Lungs, Spleen, Stomach
Parts Used Root (根 gēn)
Role in Sang Ju Yin

Sweet and neutral (raw form used here), Gan Cao harmonizes all the herbs in the formula. Combined with Jie Geng, it also benefits the throat and helps relieve cough. Its mild Heat-clearing action supports the overall treatment strategy.

Modern Research (2 studies)

  • Anti-inflammatory active component screening in Sang Ju Yin using UPLC/Q-TOF and NF-κB reporter gene assay (Laboratory study, 2016)
  • Network pharmacology analysis of the targets and mechanisms of Sang Ju Yin for COVID-19 treatment (Computational study, 2022)
See all research on the formula page

Usage & Safety

How to use this formula and important safety information

Important Medical Disclaimer

The information provided here is for educational purposes only and is not intended as medical advice or to replace consultation with a qualified healthcare professional. This formula is a dietary supplement and has not been evaluated by the FDA. It is not intended to diagnose, treat, cure, or prevent any disease.

Always consult with a qualified healthcare provider, particularly if you are pregnant, nursing, have a medical condition, or are taking other medications. Discontinue use and consult your healthcare provider if you experience any adverse reactions.

Recommended Dosage

Instructions for safe storage and consumption

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Best Time to Take

Twice daily, warm, 30–60 minutes after meals. Do not over-boil the decoction — a brief simmering preserves the volatile aromatic compounds.

Typical Duration

Acute use: 3–7 days. As an acrid-cool light formula for early-stage conditions, it should resolve symptoms quickly; reassess if no improvement within 3 days.

Dietary Advice

While taking this formula, favor light, easily digestible foods such as congee (rice porridge), clear soups, steamed vegetables, and pears (which moisten the Lungs). Drink plenty of warm water to support the formula's fluid-generating action. Avoid greasy, fried, or heavy foods that can generate Dampness and Phlegm, obstructing the Lung's function. Avoid spicy, heating foods (chili, lamb, ginger in large amounts, fried snacks) that could add Heat and counteract the formula's cooling action. Also avoid cold, raw, and iced foods and drinks, which can impair the Stomach's digestive function during illness. Alcohol should be avoided as it generates Heat and Dampness.

Modern Usage

Sang Ju Yin has the effects of releasing the Exterior with pungent and cool herbs, dispersing Wind and clearing Heat, disseminating Lung Qi, and stopping cough. It is primarily used to treat early-stage Wind-warmth with symptoms such as cough, mild body heat, slight thirst, thin white tongue coating, and a floating, rapid pulse. Clinically, it is used to treat colds, acute bronchitis, upper respiratory tract infections, pneumonia, acute conjunctivitis, and keratitis due to Wind-Heat attacking the Lungs or Liver channel.

Special Populations

Pregnancy

Generally considered safe for short-term use in pregnancy under professional guidance. All eight herbs in the formula are mild and light in nature, and none are classically listed as prohibited during pregnancy. Clinical reports exist of Sang Ju Yin being used for pregnant women with Wind-Heat coughs. However, Xing Ren (apricot kernel) contains trace amygdalin, which in excessive doses could theoretically pose concerns. At the standard low dose in this formula (6g), this is not typically considered a risk. Pregnant individuals should always consult a qualified practitioner rather than self-prescribing.

Breastfeeding

Generally considered compatible with breastfeeding. The herbs in this formula are light and mild, and there are no classically documented concerns about transfer through breast milk affecting the nursing infant. Gan Cao (licorice) in very high doses could theoretically affect fluid balance, but the dose in this formula (2.5g) is minimal. The formula's cooling nature is appropriate for acute short-term use. Breastfeeding mothers should still consult a practitioner, especially if the infant shows any signs of digestive disturbance (such as loose stools) while the mother is taking the formula.

Pediatric Use

Sang Ju Yin is widely used in pediatric practice in China and is considered appropriate for children with Wind-Heat coughs. Dosage should be reduced according to age and body weight: - Infants under 1 year: typically 1/4 to 1/3 of the adult dose - Children 1–5 years: approximately 1/3 to 1/2 of the adult dose - Children 6–12 years: approximately 1/2 to 2/3 of the adult dose The formula's light, gentle nature makes it particularly suited for children, whose constitutions are delicate. Classical case literature includes pediatric applications, such as Pu Fuzhou's treatment of a child with adenovirus pneumonia using modified Sang Ju Yin. The decoction should not be boiled for long, as the volatile aromatic components are easily lost. For young children who resist the taste, the decoction may be given in smaller, more frequent doses.

Drug Interactions

Gan Cao (Licorice root): Although present in a very small dose (2.5g), Gan Cao contains glycyrrhizin, which at higher or prolonged doses can cause potassium depletion and sodium retention. In this formula's typical short-term, low-dose use, clinically significant interactions are unlikely. However, if a patient is concurrently taking potassium-depleting diuretics, digoxin, corticosteroids, or antihypertensive medications, practitioners should be aware of this theoretical interaction and monitor accordingly.

Xing Ren (Apricot kernel): Contains small amounts of amygdalin, which can release hydrogen cyanide during metabolism. At standard formula doses (6g) the amount is well below toxic thresholds. However, caution is warranted if the patient is taking other cyanogenic compounds or medications metabolized through similar pathways.

Lian Qiao (Forsythia fruit): Has demonstrated mild anticoagulant properties in some pharmacological studies. Patients taking warfarin or other anticoagulant/antiplatelet drugs should inform their practitioner, though the low dose in this formula makes significant interaction unlikely.

General note: Because this formula is typically used for only 3–7 days for acute conditions, the risk of clinically meaningful drug interactions is low. Patients on any regular medications should always disclose this to their prescribing practitioner.

Contraindications

Avoid

Wind-Cold patterns: This formula is cooling in nature and designed exclusively for Wind-Heat or warm-pathogen conditions. Using it for cough due to Wind-Cold invasion (with chills, clear nasal discharge, thin white tongue coating, and tight pulse) will worsen the condition.

Avoid

Severe high fever with strong interior Heat: As an 'acrid-cool light formula,' Sang Ju Yin is intended for mild, early-stage Wind-Heat. When Heat has already entered deeper levels (the Qi, Ying, or Blood levels) with high fever, severe thirst, or red/crimson tongue, the formula is too light and must be replaced or substantially modified with stronger Heat-clearing agents.

Caution

Yin-deficient or chronic dry cough without external pathogen: The formula is designed for acute external invasion. Chronic cough from internal Yin deficiency or Lung dryness without an external Wind-Heat component requires nourishing, not dispersing, treatment.

Caution

Qi-deficient or Yang-deficient constitutions: People with underlying Qi or Yang weakness (who tire easily, feel cold, or have pale complexion) should use this formula with caution and for short durations only, as its cool, dispersing nature may further weaken the body's Qi.

Caution

Spleen and Stomach deficiency with loose stools: The cool nature of most ingredients may aggravate digestive weakness. Use with caution or add Spleen-supporting herbs if needed.

Cautions & Warnings

Although this formula is typically safe for most individuals, it may cause side effects in some people. Pregnant women, nursing mothers, postpartum women, and those with bad cold due to Wind-Cold should use the formula with caution.

As with any Chinese herbal remedy, it is advisable to seek guidance from a qualified TCM practitioner before beginning treatment.

Product Details

Manufacturing, supplier, and product specifications

Product Type

Granules

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Treasure of the East

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