Zhu Ling Tang

Polyporus Decoction · 豬苓湯

Also known as: Polyporus Combination, Chorei-to (Japanese Kampo name)

A classical formula from the Shang Han Lun used to promote healthy urination, clear internal Heat, and protect the body's fluids. It is especially suited for urinary problems such as difficult, painful, or bloody urination accompanied by thirst, low-grade fever, and restlessness, particularly when the body's moisture reserves are already running low. Unlike many water-draining formulas, it is designed not to dry out the body further.

Origin Shang Han Lun (傷寒論, Treatise on Cold Damage) by Zhang Zhongjing — Eastern Hàn dynasty, circa 200 CE
Composition 5 herbs
Zhu Ling
King
Zhu Ling
Fu Ling
Deputy
Fu Ling
Ze Xie
Deputy
Ze Xie
Hua Shi
Assistant
Hua Shi
E Jiao
Assistant
E Jiao
Explore composition
Available in our store
View in Store
From $24.00

Educational content Consult qualified TCM practitioners for diagnosis and treatment

Patterns Addressed

In TCM, symptoms don't appear randomly — they cluster into recognizable patterns of disharmony that reveal what's out of balance in the body. Zhu Ling Tang is designed to correct these specific patterns.

Why Zhu Ling Tang addresses this pattern

Zhu Ling Tang is the representative formula for the pattern where water and Heat bind together (水热互结 shuǐ rè hù jié) in the lower body, particularly in the Bladder, while Yin fluids are simultaneously being depleted. In this pattern, pathological water accumulates because the Bladder's Qi transformation function is impaired by Heat. The trapped water cannot flow out normally, and the Heat scorches the body's Yin fluids, creating a vicious cycle.

The formula addresses this pattern on three fronts. Zhu Ling, Fu Ling, and Ze Xie break up the water accumulation through bland percolation. Hua Shi clears the Heat component and opens the urinary passages. E Jiao replenishes the Yin that has been damaged by the Heat. This three-pronged approach resolves the water-Heat binding while preventing the diuretic action from worsening the Yin depletion.

A practitioner would look for one or more of these signs

Difficulty Urinating

Scanty, difficult, or painful urination is the cardinal symptom

Fever

Low-grade fever from internal Heat

Thirst

Thirst with desire to drink, but drinking does not fully relieve it

Insomnia

Restlessness and inability to sleep due to Heat disturbing the Heart

Nausea

Nausea or vomiting when water counterflows upward

Diarrhea

Loose stools when water pours into the intestines instead of being urinated out

Hypochondrial Pain That Is Worse On Coughing And Breathing

Cough when water Qi rises to invade the Lungs

Commonly Prescribed For

These conditions can arise from the patterns above. A practitioner would consider Zhu Ling Tang when these conditions are specifically caused by those patterns — not for all cases of these conditions.

Arises from: Water and Heat Accumulation Yin Deficiency

TCM Interpretation

TCM understands urinary tract infections as a form of "lin" (淋, strangury), most commonly "Heat strangury" (热淋). The condition arises when Damp-Heat invades the lower body, particularly the Bladder, disrupting its Qi transformation and causing painful, frequent, or difficult urination. In recurrent cases, the classical text Zhu Bing Yuan Hou Lun noted that "strangury arises from Kidney deficiency with Bladder Heat," recognizing that an underlying Kidney Yin weakness makes the body vulnerable to repeated episodes.

When the Kidney Yin is depleted, the body cannot properly cool and moisten the urinary system, creating conditions that favor Heat accumulation. Each episode of infection further damages the Yin, setting up a self-perpetuating cycle. This is why purely antibacterial or Heat-clearing approaches often fail for recurrent UTIs from a TCM perspective: they address the surface infection but not the underlying Yin deficiency that allows it to keep returning.

Why Zhu Ling Tang Helps

Zhu Ling Tang breaks the cycle of recurrent UTI by simultaneously addressing both the acute infection (Damp-Heat) and the underlying vulnerability (Yin deficiency). Zhu Ling, Fu Ling, and Ze Xie drain the pathological Dampness from the urinary tract, while Hua Shi clears Bladder Heat and soothes the irritated urinary passages. Crucially, E Jiao nourishes the Kidney Yin that has been depleted by repeated infections, strengthening the body's own defenses against future episodes.

Clinical studies have shown that modified Zhu Ling Tang achieved a 98% total effective rate in treating urinary tract infections, significantly outperforming conventional therapy alone. The formula's ability to drain water without harming Yin makes it especially well suited for patients with recurrent infections who show signs of fluid depletion such as dry mouth, a red tongue with little coating, and a thin, rapid pulse.

Also commonly used for

Cystitis

Bladder inflammation with painful, difficult urination

Kidney Stones

Urinary stones with Heat signs and difficult urination

Blood In Urine

Hematuria from Damp-Heat damaging the urinary tract lining

Urinary Retention

Postpartum or post-surgical urinary retention with Heat signs

Edema

Edema with Yin deficiency, especially in chronic kidney disease

Nephrotic Syndrome

Proteinuria and edema with underlying Yin deficiency

Prostatitis

Chronic prostatitis with Damp-Heat and Yin deficiency features

Ascites

Hepatic ascites when accompanied by Yin deficiency and Heat signs

What This Formula Does

Every TCM formula has a specific set of actions — here's what Zhu Ling Tang does in the body, explained in both everyday and TCM terms

Therapeutic focus

In practical terms, Zhu Ling Tang is primarily used to support these areas of health:

TCM Actions

In TCM terminology, these are the specific therapeutic actions that Zhu Ling Tang performs to restore balance in the body:

How It Addresses the Root Cause

TCM doesn't just suppress symptoms — it aims to resolve the underlying imbalance. Here's how Zhu Ling Tang works at the root level.

Zhu Ling Tang addresses a condition in which Heat and water become mutually bound in the lower body, particularly affecting the Kidneys and Urinary Bladder, while Yin fluids are simultaneously being damaged. The disease logic unfolds in stages: pathogenic Heat enters the interior (often through the Yangming or Shaoyin level during a febrile illness, or from chronic lower-burner Damp-Heat), where it encounters the body's water metabolism. Instead of flowing freely, the water stagnates, and the Heat binds with it. This water-Heat binding obstructs the Bladder's ability to transform and excrete fluids, producing the hallmark symptom of urinary difficulty.

At the same time, the Heat scorches the Yin fluids, causing thirst with a desire to drink, a red tongue, and a thin rapid pulse. Because the Kidneys and Heart are connected through the Shaoyin channel, when Kidney Yin can no longer ascend to cool the Heart, Heart Fire flares upward, causing irritability and insomnia. Meanwhile, the bound water may overflow into other pathways: rising to the Lungs it produces coughing, disturbing the Stomach it causes nausea and vomiting, and descending into the intestines it produces diarrhea. The key insight is that this is not simple Dampness or simple Heat, but a tangled interplay of both, complicated by Yin damage. Ordinary diuretic formulas would drain the water but further injure the Yin. Ordinary Yin-nourishing formulas would retain the Dampness. This formula uniquely resolves both problems simultaneously.

Formula Properties

Every formula has an inherent temperature, taste, and affinity for specific organs — these properties determine how it interacts with the body

Overall Temperature

Cool

Taste Profile

Predominantly bland and sweet with a cool undertone. The bland taste from Zhu Ling, Fu Ling, Ze Xie, and Hua Shi drives the diuretic, Dampness-draining action, while the sweet quality from E Jiao and Fu Ling gently nourishes Yin and protects fluids.

Channels Entered

Kidney Bladder Lung Heart Stomach

Ingredients

5 herbs

The herbs that make up Zhu Ling Tang, organized by their role in the prescription

King — Main ingredient driving the formula
Deputy — Assists and enhances the King
Assistant — Supports or moderates other herbs
King — Main ingredient driving the formula
Zhu Ling

Zhu Ling

Polyporus

Dosage 9 - 12g
Temperature Neutral
Taste Sweet
Organ Affinity Urinary Bladder, Kidneys
Preparation Remove skin before use (去皮)

Role in Zhu Ling Tang

The chief water-draining herb, Zhu Ling enters the Kidney and Bladder channels and specializes in bland percolation to promote urination. It directly addresses the core problem of water accumulation in the lower body by opening the water pathways and restoring normal fluid metabolism.
Deputies — Assists and enhances the King
Fu Ling

Fu Ling

Poria-cocos mushrooms

Dosage 9 - 12g
Temperature Neutral
Taste Sweet
Organ Affinity Heart, Kidneys, Lungs, Spleen

Role in Zhu Ling Tang

Reinforces the King herb's water-draining action through its bland, sweet, and neutral nature. Fu Ling strengthens the Spleen's ability to transport fluids and calms the Heart spirit, helping address the restlessness and insomnia that accompany this pattern.
Ze Xie

Ze Xie

Water plantain

Dosage 9 - 12g
Temperature Cold
Taste Sweet
Organ Affinity Urinary Bladder, Kidneys

Role in Zhu Ling Tang

Directly enters the Kidney and Bladder to drain accumulated water downward and clear Heat from the lower body. Ze Xie powerfully promotes urination and works alongside the two Ling herbs to ensure water is expelled through the urinary tract rather than pooling internally.
Assistants — Supports or moderates other herbs
Hua Shi

Hua Shi

Talc

Dosage 9 - 12g
Temperature Cold
Taste Sweet
Organ Affinity Urinary Bladder, Stomach
Preparation Crush before decocting (碎)

Role in Zhu Ling Tang

Sweet, bland, and cold in nature, Hua Shi clears Heat from the Bladder and smooths the urinary passages. It is especially valuable for painful or difficult urination caused by Heat, and its slippery quality helps open blocked water channels. It also gently protects the Stomach's fluids.
E Jiao

E Jiao

Donkey-hide gelatin

Dosage 9 - 12g
Temperature Neutral
Taste Sweet
Organ Affinity Kidneys, Liver, Lungs
Preparation Dissolve separately in the strained decoction (烊化, added after the other herbs are decocted and strained)

Role in Zhu Ling Tang

The key ingredient that distinguishes this formula from other water-draining prescriptions. E Jiao nourishes Yin and Blood, preventing the diuretic herbs from depleting the body's precious fluids. It ensures the formula drains pathological water while preserving healthy Yin, making this a safe choice for patients who are already somewhat fluid-depleted.

Why This Combination Works

How the herbs in Zhu Ling Tang complement each other

Overall strategy

The pathomechanism involves water and Heat binding together in the lower body while Yin fluids are being consumed. The prescription must therefore accomplish three things simultaneously: drain the pathological water, clear the Heat, and protect the Yin from further damage. This is a delicate balancing act, since most water-draining herbs tend to dry out the body further.

King herbs

Zhu Ling (Polyporus) serves as the King because it enters the Kidney and Bladder channels and is the strongest bland-percolating diuretic in the formula. It directly opens the water pathways to resolve the primary symptom of difficult urination. Its bland, neutral character makes it effective at draining water without adding Heat or Cold to the picture.

Deputy herbs

Fu Ling (Poria) and Ze Xie (Alisma) both reinforce the King's water-draining action from different angles. Fu Ling supports the Spleen's fluid-transporting role and calms the spirit, addressing the restlessness component. Ze Xie directly enters the Kidney and Bladder to powerfully drain water downward and clear Heat from the lower body. Together with Zhu Ling, these three herbs form a potent water-resolving team.

Assistant herbs

Hua Shi (Talcum) is a reinforcing assistant that adds Heat-clearing power to the formula while its smooth, slippery quality helps unblock painful urinary passages. It specifically targets Bladder Heat and urinary tract discomfort. E Jiao (Donkey-hide Gelatin) is a restraining assistant that prevents the four water-draining herbs from depleting the body's Yin fluids. It nourishes the Blood and Yin, ensuring the formula does not cause further fluid loss in a patient who is already Yin-deficient. This is what the classical commentator Zhao Yuhuang meant when he wrote that the formula's true purpose is "entirely in nourishing Yin, not merely promoting urination."

Notable synergies

The pairing of E Jiao with the three diuretic herbs (Zhu Ling, Fu Ling, Ze Xie) creates the formula's signature effect: draining water without harming Yin. The combination of Hua Shi and E Jiao is also noteworthy: Hua Shi clears Heat and opens passages while E Jiao nourishes and protects, together achieving what classical physicians described as "nourishing the formless (Yin) to move the formed (water)." This contrasts sharply with Wu Ling San, which uses Gui Zhi (Cinnamon Twig) to warm and move water, making the two formulas fundamentally different despite treating similar symptoms.

How to Prepare

Traditional preparation instructions for Zhu Ling Tang

In the original Shang Han Lun method, take the five ingredients with approximately 800 mL of water. First decoct the four herbs (Zhu Ling, Fu Ling, Ze Xie, Hua Shi) until the liquid is reduced to approximately 400 mL. Strain out the dregs, then dissolve the E Jiao (donkey-hide gelatin) into the hot liquid while stirring until fully melted.

Take approximately 140 mL of the warm decoction per dose, three times daily. In modern practice, the formula is typically prepared as a standard water decoction with E Jiao dissolved separately and stirred into the strained liquid in two divided doses.

Common Modifications

How practitioners adapt Zhu Ling Tang for specific situations

Added
Zhi Zi

9g, clears Heat and directs it downward through urination

Che Qian Zi

9 - 15g, promotes urination and clears Heat from the Bladder

When Heat signs are prominent with strong burning on urination, adding Zhi Zi and Che Qian Zi strengthens the Heat-clearing and water-draining capacity of the formula.

Educational content — always consult a qualified healthcare provider or TCM practitioner before using any herbal formula.

Contraindications

Situations where Zhu Ling Tang should not be used or requires extra caution

Avoid

Profuse sweating with thirst and Stomach dryness. The Shang Han Lun (Clause 224) explicitly states: 'When there is Yangming disease with profuse sweating and thirst, Zhu Ling Tang must not be given, because the heavy sweating has already dried the Stomach, and the formula would further deplete fluids by promoting urination.'

Avoid

Severe Yin deficiency with abundant Heat and greatly damaged fluids. When Yin is already severely depleted, the diuretic herbs in this formula risk further exhausting vital fluids despite the presence of E Jiao.

Avoid

Cold-type urinary difficulty without Heat signs. This formula is designed for water-Heat binding patterns. If there is no Heat (no red tongue, no rapid pulse, no thirst), a warming formula such as Wu Ling San is more appropriate.

Caution

Pronounced Dampness without Yin deficiency. In cases of overwhelming Dampness with a greasy tongue coat and no signs of Yin damage, stronger Dampness-draining formulas without the Yin-nourishing component may be more suitable.

Caution

Spleen Yang deficiency with loose stools and poor appetite. The cool and bland percolating nature of most herbs in this formula may further weaken an already deficient Spleen Yang.

Special Populations

Important considerations for pregnancy, breastfeeding, and pediatric use

Pregnancy

Use with caution during pregnancy. Hua Shi (Talcum) has a slippery, downward-directing nature that some classical sources consider inadvisable during pregnancy due to its potential to promote downward movement. E Jiao (Donkey-hide Gelatin) is generally considered safe and is used in the classical pregnancy formula Jiao Ai Tang. Zhu Ling and Ze Xie are strong diuretics that could potentially deplete fluids needed for fetal development if used improperly. The formula's overall diuretic action warrants caution, as excessive fluid loss during pregnancy may affect amniotic fluid levels. Should only be used during pregnancy under the guidance of an experienced practitioner when the specific water-Heat pattern is clearly present, and should be discontinued once symptoms resolve.

Breastfeeding

No specific contraindications for breastfeeding have been documented for this formula. The ingredients are generally considered mild in terms of systemic toxicity. However, the strong diuretic action of the formula could theoretically reduce breast milk production by promoting fluid loss. E Jiao (Donkey-hide Gelatin) is a nourishing substance unlikely to cause concern. Hua Shi (Talcum) is a mineral that is poorly absorbed systemically, so transfer into breast milk is unlikely to be significant. If a breastfeeding mother requires this formula, adequate fluid intake should be maintained and the formula used only for the minimum duration needed. Consult a qualified practitioner.

Children

Zhu Ling Tang can be used in children when the water-Heat binding pattern is clearly present, but dosages must be adjusted according to age and weight. A general guideline is one-third to one-half the adult dose for children aged 6-12, and one-quarter for children under 6. E Jiao (Donkey-hide Gelatin) is generally well tolerated but can be difficult for young children to digest. Hua Shi (Talcum) should be wrapped in cloth for decoction to prevent sediment. The formula's diuretic effect requires monitoring of fluid intake in children to prevent dehydration. For pediatric urinary tract infections, this formula is typically used for short courses (3-7 days) with close follow-up. Not recommended for infants without specialist guidance.

Drug Interactions

If you are taking pharmaceutical medications, be aware of these potential interactions with Zhu Ling Tang

Diuretic medications (furosemide, hydrochlorothiazide, spironolactone): Zhu Ling Tang has significant diuretic effects. Combining it with pharmaceutical diuretics may lead to excessive fluid and electrolyte loss, particularly potassium depletion. Monitoring of electrolytes and hydration status is recommended if concurrent use is necessary.

Lithium: The diuretic action of the formula may alter lithium clearance. Increased diuresis could initially increase lithium excretion, but if dehydration occurs, lithium levels could rise to toxic concentrations. Lithium levels should be monitored closely.

Antihypertensive medications: The fluid-draining effect may potentiate the blood-pressure-lowering action of antihypertensives, potentially causing hypotension.

Anticoagulants and antiplatelet drugs (warfarin, aspirin): E Jiao (Donkey-hide Gelatin) has mild hemostatic properties and may theoretically interact with anticoagulant therapy, though clinically significant interactions have not been well documented. Caution is warranted.

Usage Guidance

Practical advice for getting the most out of Zhu Ling Tang

Best time to take

Two to three times daily between meals (approximately 30-60 minutes before or after eating). E Jiao should be dissolved into the warm, strained decoction just before drinking.

Typical duration

Acute conditions (UTI, acute nephritis flare): 5-14 days. Chronic conditions may require 2-4 weeks with periodic reassessment.

Dietary advice

While taking this formula, avoid greasy, rich, and deep-fried foods that generate Dampness and obstruct the waterways the formula is trying to clear. Cold and raw foods should also be limited, as they can impair the Spleen's fluid-transforming function. Spicy, hot, and alcohol-rich foods should be minimized as they can worsen internal Heat. Favor bland, lightly cooked foods such as congee, barley soup (yi yi ren porridge), winter melon, and lotus seed. Drink adequate warm water to support the formula's diuretic action and prevent excessive fluid depletion, but avoid forcing excess fluid intake.

Zhu Ling Tang originates from Shang Han Lun (傷寒論, Treatise on Cold Damage) by Zhang Zhongjing Eastern Hàn dynasty, circa 200 CE

Classical Texts

Key passages from the classical Chinese medical texts that first described Zhu Ling Tang and its clinical use

Shang Han Lun (Clause 223)

Original: 若脉浮,发热,渴欲饮水,小便不利者,猪苓汤主之。

Translation: If there is a floating pulse, fever, thirst with desire to drink water, and urinary difficulty, Zhu Ling Tang governs.

Shang Han Lun (Clause 224)

Original: 阳明病,汗出多而渴者,不可与猪苓汤。以汗多胃中燥,猪苓汤复利其小便故也。

Translation: In Yangming disease, when there is profuse sweating and thirst, Zhu Ling Tang must not be given. This is because profuse sweating has already dried the Stomach, and Zhu Ling Tang would further promote urination [worsening the fluid loss].

Shang Han Lun (Clause 319)

Original: 少阴病,下利六七日,咳而呕渴,心烦不得眠者,猪苓汤主之。

Translation: In Shaoyin disease with diarrhea for six or seven days, coughing with vomiting and thirst, irritability and inability to sleep, Zhu Ling Tang governs.

Jin Gui Yao Lue (Chapter 1, Zang Fu Jing Luo Xian Hou Bing)

Original: 夫诸病在脏,欲攻之,当随其所得而攻之。如渴者,与猪苓汤。余皆仿此。

Translation: When diseases reside in the Zang organs and one wishes to attack them, one should follow their root cause and attack accordingly. For example, for thirst, give Zhu Ling Tang. All others may be treated by analogy.

Zhao Yuhuang, quoted in Yi Zong Jin Jian

Original: 仲景制猪苓一汤,以行阳明、少阴二经水热,然其旨全在益阴,不专利水。

Translation: Zhongjing formulated Zhu Ling Tang to move the water-Heat of both the Yangming and Shaoyin channels. Yet its true purpose lies entirely in nourishing Yin, not solely in promoting urination.

Historical Context

How Zhu Ling Tang evolved over the centuries — its origins, lineage, and place in the broader tradition of Chinese medicine

Zhu Ling Tang originates from Zhang Zhongjing's Shang Han Lun (Treatise on Cold Damage, c. 200 CE) and also appears in his Jin Gui Yao Lue (Synopsis of the Golden Cabinet). Notably, in the Jin Gui Yao Lue, Zhu Ling Tang is the only formula mentioned in the programmatic first chapter on Zang-Fu diagnosis, presented as a model for how to treat organ diseases by addressing their root cause. Some scholars, such as Wang Sanhu, have argued that this placement reveals its status as a paradigmatic formula for Zang-Fu-based pattern differentiation, giving it a significance far beyond its modest five-ingredient composition.

The formula has an important structural relationship to Wu Ling San (Five-Ingredient Powder with Poria): it can be understood as Wu Ling San with Gui Zhi and Bai Zhu removed and E Jiao and Hua Shi added. This swap transforms the formula from a warming Yang-supporting diuretic into a cooling Yin-protecting one. Classical commentators like Xu Hong (Jin Jing Nei Tai Fang Yi) and Zhao Yuhuang (quoted in Yi Zong Jin Jian) emphasized this contrast: Wu Ling San warms the Kidneys to move water (for Taiyang Cold-water patterns), while Zhu Ling Tang nourishes Yin to move water (for Yangming and Shaoyin Heat patterns). Ke Yunbo (Shang Han Lai Su Ji) offered a particularly elegant reading, noting that the dark-colored Zhu Ling and E Jiao enter the Kidneys to treat the root, while the white Fu Ling and Hua Shi enter the Lungs to nourish the source of Yin, creating a harmonious water-fire interplay.

Modern Research

A published study investigating the pharmacological effects or clinical outcomes of Zhu Ling Tang

1

Adjuvant Therapy Efficacy of Herbal Medicine Zhu Ling Tang for Primary Glomerulonephritis: Systematic Review and Meta-Analysis (2020)

Journal of Internal Korean Medicine, 2020, Vol. 41, No. 4, pp. 644-660

This systematic review and meta-analysis evaluated the clinical evidence for Zhu Ling Tang as an adjuvant therapy in primary glomerulonephritis. The pooled analysis of multiple controlled trials found that adding Zhu Ling Tang to conventional treatment improved overall therapeutic efficacy, reduced proteinuria, and improved kidney function markers compared to conventional treatment alone.

Link

Research on TCM formulas is growing but still limited by Western clinical trial standards. These studies provide emerging evidence and should be considered alongside practitioner expertise.