Wan Ying Gao

Universal Response Plaster · 萬應膏

Also known as: Wan Ying Gao Yao, Universal Plaster

A classical external plaster used to treat skin sores, abscesses, boils, and deep tissue swellings including phlegm nodules. It works by promoting blood circulation, reducing swelling and pain, dispelling Wind-Dampness, and drawing out toxins through topical application. The name literally means 'universally effective plaster,' reflecting its broad use in traditional external medicine.

Origin Yi Zong Jin Jian (《医宗金鉴》), Volume 62 — Qīng dynasty, 1742 CE
Composition 20 herbs
Dang Gui
King
Dang Gui
Zhi Chuan Wu
Deputy
Zhi Chuan Wu
Cao Guo
Deputy
Cao Guo
Da Huang
Deputy
Da Huang
Shu Di huang
Assistant
Shu Di huang
Chi Shao
Assistant
Chi Shao
Bai Zhi
Assistant
Bai Zhi
Qiang Huo
Assistant
Qiang Huo
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Educational content Consult qualified TCM practitioners for diagnosis and treatment

Patterns Addressed

In TCM, symptoms don't appear randomly — they cluster into recognizable patterns of disharmony that reveal what's out of balance in the body. Wan Ying Gao is designed to correct these specific patterns.

Why Wan Ying Gao addresses this pattern

This formula addresses Toxic Heat generating pus through its combination of Heat-clearing and toxin-resolving herbs applied directly to the affected area. Da Huang, Chi Shao, and Ku Shen clear Heat and resolve toxins, while Bai Zhi and Chuan Shan Jia help draw pus to the surface for drainage. Xuan Shen and Sheng Di Huang cool the Blood to prevent the Heat from penetrating deeper. The plaster form allows sustained contact with the lesion, providing continuous therapeutic action.

A practitioner would look for one or more of these signs

Periappendiceal Abscess

Red, hot, swollen skin lesions progressing to pus formation

Boils

Painful boils and carbuncles on the back or elsewhere

Sore

Toxic sores with surrounding redness and heat

Swelling

Localized inflammatory swelling

Commonly Prescribed For

These conditions can arise from the patterns above. A practitioner would consider Wan Ying Gao when these conditions are specifically caused by those patterns — not for all cases of these conditions.

Arises from: Toxic Heat generating Pus

TCM Interpretation

In TCM, skin abscesses are understood as the result of Heat-toxins accumulating in the flesh and obstructing local Qi and Blood flow. When Qi and Blood stagnate, the area becomes swollen, red, hot, and painful. If the toxins are not resolved, the stagnant fluids transform into pus. The location, depth, and temperature of the abscess help determine whether the condition is more Yang (superficial, hot, red) or Yin (deep, cool, pale) in nature. The formula was originally indicated for treating all types of abscesses including those on the back (发背) and opposite-mouth sores (对口疮).

Why Wan Ying Gao Helps

Wan Ying Gao provides sustained topical delivery of Heat-clearing herbs (Da Huang, Ku Shen, Chi Shao) directly to the abscess site, while Blood-moving herbs (Dang Gui, Chuan Shan Jia) break up the local stagnation that allows toxins to accumulate. Bai Zhi is classically renowned for its ability to expel pus and reduce swelling in external sores. The plaster format is especially well-suited for abscesses because it maintains continuous contact, drawing toxins to the surface while protecting the area from further contamination.

Also commonly used for

Boils

Boils and furuncles, including those on the back (发背)

Nodules

Subcutaneous phlegm nodules and scrofula (痰核)

Sore

Various toxic skin sores (诸疮)

Swelling

Deep tissue swellings and streaming abscesses (流注)

Trauma

Traumatic injuries with local swelling and bruising

Muscle Pain

Muscle and sinew pain from obstruction

What This Formula Does

Every TCM formula has a specific set of actions — here's what Wan Ying Gao does in the body, explained in both everyday and TCM terms

Therapeutic focus

In practical terms, Wan Ying Gao is primarily used to support these areas of health:

How It Addresses the Root Cause

TCM doesn't just suppress symptoms — it aims to resolve the underlying imbalance. Here's how Wan Ying Gao works at the root level.

Wan Ying Gao addresses a range of external surgical conditions that share a common underlying mechanism: obstruction and stagnation. When the body's defensive Qi is insufficient or when external pathogenic factors such as Wind, Cold, and Dampness invade the flesh, muscles, and channels, the smooth flow of Qi and Blood becomes blocked. Over time, this stagnation generates localized accumulations that can manifest as abscesses (痈疽), deep sores on the back (发背), or subcutaneous nodules (痰核). When pathogenic factors lodge deeply in the tissues, toxic substances accumulate and the local environment becomes one of mixed Cold-stagnation and Heat-toxin, causing swelling, pain, pus formation, or hard lumps that resist resolution.

In the case of phlegm nodules and deep-flowing abscesses (流注), the pathomechanism involves Phlegm and Blood stasis congealing together in the channels and tissues, often driven by underlying Cold that prevents proper circulation. The tissues become starved of fresh Qi and Blood, which impairs the body's ability to either push the lesion to the surface for drainage or close and heal a wound. The formula works topically to restore local circulation, break through stagnation, draw out toxins, and encourage the body's own healing response at the site of disease.

Formula Properties

Every formula has an inherent temperature, taste, and affinity for specific organs — these properties determine how it interacts with the body

Overall Temperature

Warm

Taste Profile

Predominantly acrid and bitter with warm aromatic qualities. The acrid taste disperses stagnation and opens the channels, the bitter taste clears Heat-toxin and drains pus, and the aromatic herbs penetrate deeply into the tissues.

Channels Entered

Ingredients

20 herbs

The herbs that make up Wan Ying Gao, organized by their role in the prescription

King — Main ingredient driving the formula
Deputy — Assists and enhances the King
Assistant — Supports or moderates other herbs
Envoy — Directs the formula to its target
King — Main ingredient driving the formula
Dang Gui

Dang Gui

Dong quai

Dosage 15g
Temperature Warm
Taste Pungent, Sweet
Organ Affinity Heart, Liver, Spleen

Role in Wan Ying Gao

Nourishes and invigorates Blood, reduces swelling, and promotes healing of sores. As the primary Blood-moving herb in the formula, it ensures that stagnant Blood is dispersed so toxins can be resolved and new tissue can form.
Deputies — Assists and enhances the King
Zhi Chuan Wu

Zhi Chuan Wu

Prepared Sichuan aconite

Dosage 15g
Temperature Hot
Taste Bitter, Pungent
Organ Affinity Spleen, Heart, Kidneys, Liver

Role in Wan Ying Gao

Powerfully expels Wind-Dampness and Cold, strongly alleviates pain. Its warming and penetrating nature helps the formula reach deep into obstructed tissues to disperse cold stagnation.
Cao Guo

Cao Guo

Tsaoko fruits

Dosage 15g
Temperature Warm
Taste Pungent
Organ Affinity Spleen, Stomach

Role in Wan Ying Gao

Works synergistically with Chuan Wu to expel Wind-Dampness and relieve pain. Together they form a potent pain-relieving pair that penetrates channels and collaterals to open blockages.
Da Huang

Da Huang

Rhubarb

Dosage 15g
Temperature Cold
Taste Bitter
Organ Affinity Spleen, Stomach, Large Intestine, Liver, Pericardium

Role in Wan Ying Gao

Clears Heat, resolves toxins, and invigorates Blood to disperse stasis. Applied externally, it reduces swelling and helps draw out purulent matter from abscesses.
Assistants — Supports or moderates other herbs
Shu Di huang

Shu Di huang

Prepared rehmannia

Dosage 15g
Temperature Warm
Taste Sweet
Organ Affinity Kidneys, Liver

Role in Wan Ying Gao

Cools the Blood and nourishes Yin, counterbalancing the hot and acrid nature of Chuan Wu and Cao Wu. Helps prevent excessive dryness and promotes tissue regeneration.
Chi Shao

Chi Shao

Red peony roots

Dosage 15g
Temperature Cool
Taste Bitter
Organ Affinity Liver

Role in Wan Ying Gao

Clears Heat, cools Blood, and disperses Blood stasis. Supports the formula's ability to reduce redness, swelling, and pain at the site of sores and abscesses.
Bai Zhi

Bai Zhi

Angelica roots

Dosage 15g
Temperature Warm
Taste Pungent
Organ Affinity Spleen, Stomach, Lungs

Role in Wan Ying Gao

Expels Wind, reduces swelling, expels pus, and alleviates pain. A key herb for treating skin sores and abscesses, it helps draw toxins to the surface and promotes drainage.
Qiang Huo

Qiang Huo

Notopterygium roots

Dosage 15g
Temperature Warm
Taste Bitter, Pungent
Organ Affinity Urinary Bladder, Kidneys

Role in Wan Ying Gao

Releases the exterior and expels Wind-Dampness, particularly in the upper body and back. Helps the formula address sores and pain in these regions.
Du Huo

Du Huo

Pubescent angelica roots

Dosage 15g
Temperature Warm
Taste Bitter, Pungent
Organ Affinity Urinary Bladder, Kidneys

Role in Wan Ying Gao

Expels Wind-Dampness from the lower body and deeper tissues. Paired with Qiang Huo, it ensures the formula can reach all levels and regions of the body.
Bai Qian

Bai Qian

Cynanchum roots and rhizomes

Dosage 15g
Temperature Warm
Taste Pungent, Sweet
Organ Affinity Lungs

Role in Wan Ying Gao

Clears Heat, resolves toxins, disperses swelling, and promotes tissue healing. Particularly useful for sores that are swollen, hot, and painful.
Bai Ji

Bai Ji

Bletilla rhizomes

Dosage 15g
Temperature Cold
Taste Bitter, Sweet
Organ Affinity Stomach, Liver, Lungs

Role in Wan Ying Gao

Astringes and stops bleeding, reduces swelling, and promotes tissue regeneration. Helps close wounds and generate new flesh in ulcerated sores.
Ku Shen

Ku Shen

Sophora roots

Dosage 15g
Temperature Cold
Taste Bitter
Organ Affinity Urinary Bladder, Heart, Large Intestine, Liver, Stomach

Role in Wan Ying Gao

Clears Heat, dries Dampness, and kills parasites. Addresses the Damp-Heat and toxic factors that contribute to skin eruptions and deep sores.
Xuan Shen

Xuan Shen

Ningpo figwort roots

Dosage 15g
Temperature Cold
Taste Bitter
Organ Affinity Large Intestine, Liver, Stomach

Role in Wan Ying Gao

Clears Heat, cools Blood, nourishes Yin, and softens hardness. Particularly important for addressing phlegm nodules and scrofula by dissolving hardened masses.
Gan Sui

Gan Sui

Kansui roots

Dosage 15g
Temperature Cold
Taste Bitter
Organ Affinity Spleen, Kidneys, Large Intestine, Lungs

Role in Wan Ying Gao

Warms the channels and promotes Blood circulation. Its warming nature helps the medicinal substances penetrate through the skin and into deeper tissues.
Wu Yao

Wu Yao

Lindera roots

Dosage 15g
Temperature Warm
Taste Pungent
Organ Affinity Urinary Bladder, Kidneys, Lungs, Spleen

Role in Wan Ying Gao

Promotes the movement of Qi and alleviates pain. Where Qi stagnation underlies the swelling and pain, Wu Yao ensures smooth Qi flow to support Blood movement.
Chuan Lian Zi

Chuan Lian Zi

Sichuan chinaberries

Dosage 15g
Temperature Cold
Taste Bitter
Organ Affinity Spleen, Liver, Small Intestine

Role in Wan Ying Gao

Powerfully invigorates Blood, disperses stasis, reduces swelling, and expels pus. Its unique penetrating quality helps break through channel obstructions and draw abscesses to a head.
Tu

Tu Mu Bie (土木鳖)

Dosage 15g

Role in Wan Ying Gao

Clears Heat, resolves toxins, disperses swelling, and reduces masses. Particularly useful for stubborn, deep-seated swellings and toxic sores.
Xiang Ru

Xiang Ru

Vietnamese balm

Dosage 15g
Temperature Warm
Taste Pungent
Organ Affinity Lungs, Stomach

Role in Wan Ying Gao

Promotes tissue regeneration and wound healing. Helps close chronic, non-healing sores by encouraging the growth of new flesh.
Qing Fen

Qing Fen

Calomelas

Dosage 250g per 500g oil
Temperature Cold
Taste Pungent
Organ Affinity Urinary Bladder, Kidneys, Liver
Preparation Added separately after straining the medicated oil; not soaked with the other herbs

Role in Wan Ying Gao

Acts as the plaster base material, providing the adhesive matrix. Also has mild toxin-resolving and tissue-drying properties that help draw moisture from damp sores.
Envoy — Directs the formula to its target
Gan Cao

Gan Cao

Liquorice

Dosage 15g
Temperature Neutral
Taste Sweet
Organ Affinity Heart, Lungs, Spleen, Stomach

Role in Wan Ying Gao

Harmonizes the formula and moderates the toxicity of Chuan Wu and Cao Wu. Also clears Heat and resolves toxins in its own right.

Why This Combination Works

How the herbs in Wan Ying Gao complement each other

Overall strategy

Wan Ying Gao is designed as a broad-spectrum external plaster that simultaneously moves Blood, expels Wind-Dampness, clears Heat-toxins, and promotes tissue healing. The formula addresses the full lifecycle of sores and abscesses: dispersing the initial stagnation, drawing out toxins, and regenerating damaged tissue.

King herbs

Dang Gui serves as the King, anchoring the formula's Blood-moving and tissue-nourishing actions. In external medicine, stagnant Blood is considered the root of most swellings and sores. By invigorating Blood circulation at the site of application, Dang Gui creates the conditions for toxins to be expelled and new tissue to form.

Deputy herbs

Chuan Wu and Cao Wu form a powerful pair that penetrates deep into channels and collaterals, expelling Wind-Cold-Dampness and strongly relieving pain. Da Huang complements them from the opposite temperature: its cold nature clears Heat-toxins and further activates Blood, helping to reduce hot, swollen, inflamed lesions.

Assistant herbs

The Assistants fall into several functional groups. For Blood cooling and Yin protection, Sheng Di Huang, Chi Shao, and Xuan Shen cool the Blood, counteract the warming herbs' drying tendency, and soften hardened masses. For Wind-Dampness expulsion, Qiang Huo and Du Huo work as a pair covering upper and lower body regions respectively. For toxin resolution and tissue healing, Bai Zhi, Bai Lian, Bai Ji, and Ku Shen clear Heat, expel pus, dry Dampness, and promote wound closure. Chuan Shan Jia and Tu Mu Bie provide strong penetrating power to break through obstructions and disperse deep swellings. Guan Gui warms the channels to enhance penetration of all the medicinals through the skin. Wu Yao moves Qi to support Blood circulation. Xiang Pi promotes the regeneration of flesh. Ding Fen provides the plaster matrix while contributing mild toxin-resolving action.

Envoy herbs

Gan Cao harmonizes the entire composition and critically moderates the toxicity of Chuan Wu and Cao Wu, making the plaster safer for prolonged skin contact. It also contributes its own mild Heat-clearing and detoxifying effects.

Notable synergies

The Chuan Wu and Cao Wu pairing creates a synergistic analgesic effect stronger than either alone, while Gan Cao's detoxifying action tempers their aconitine toxicity. The Qiang Huo and Du Huo pair ensures comprehensive Wind-Dampness coverage across all body regions. Dang Gui paired with Chi Shao and Sheng Di Huang balances Blood invigoration with Blood cooling, preventing the formula from being either too warming or too cold at the application site.

How to Prepare

Traditional preparation instructions for Wan Ying Gao

Soak the 19 herbal ingredients (excluding Ding Fen/lead powder) in 2.5 kg of pure sesame oil. The soaking duration varies by season: 5 days in spring, 3 days in summer, 7 days in autumn, and 10 days in winter.

Once the soaking period is complete, transfer to a clean large pot and heat slowly over gentle fire until the herbs are fully exhausted and float to the surface. Remove from heat briefly, then strain through a cloth bag to remove all residue. Weigh the resulting medicated oil carefully.

For every 500 g of medicated oil, add 250 g of Ding Fen (lead powder). Stir continuously with peach and willow branches until the mixture becomes black as lacquer and shiny as a mirror. Test readiness by dropping a bead into water: it should hold its shape as a firm pearl. Spread the finished plaster thinly onto paper for application.

Common Modifications

How practitioners adapt Wan Ying Gao for specific situations

Added
Jin Yin Hua

15g, strongly clears Heat-toxins

Lian Qiao

15g, resolves toxins and disperses swelling

Adding Jin Yin Hua and Lian Qiao strengthens the formula's Heat-clearing and toxin-resolving capacity for sores where Heat-toxin predominates.

Educational content — always consult a qualified healthcare provider or TCM practitioner before using any herbal formula.

Contraindications

Situations where Wan Ying Gao should not be used or requires extra caution

Avoid

Pregnancy. The formula contains Chuan Wu (川乌), Cao Wu (草乌), and Chuan Shan Jia (穿山甲), all of which are contraindicated in pregnancy. Even topical application of aconitum-containing plasters carries risk of transdermal absorption of toxic alkaloids.

Avoid

Open wounds or broken skin at the application site. Ding Fen (定粉, lead powder) and aconitum alkaloids from Chuan Wu and Cao Wu can be absorbed more readily through broken skin, increasing toxicity risk.

Avoid

Known allergy or skin sensitivity to any ingredient. If redness, itching, blistering, or rash develops at the application site, the plaster should be removed immediately.

Caution

Yin-deficient Heat patterns or hot-type sores (红肿热痛 with obvious Heat signs). The formula contains warm and hot herbs like Chuan Wu, Cao Wu, and Guan Gui, which would aggravate Heat-toxin conditions where Fire is dominant.

Avoid

Application near the eyes, mouth, mucous membranes, or genitalia. The formula contains highly stimulating and toxic ingredients that can cause severe irritation to sensitive tissues.

Caution

Children, elderly, and individuals with impaired liver or kidney function. These populations are more susceptible to the toxic effects of aconitum alkaloids and lead compounds, even through topical absorption.

Caution

Prolonged continuous use over large areas of skin. Extended application increases the risk of cumulative lead absorption from Ding Fen and transdermal absorption of aconitum alkaloids.

Special Populations

Important considerations for pregnancy, breastfeeding, and pediatric use

Pregnancy

Contraindicated during pregnancy. This formula contains raw Chuan Wu (川乌, Aconitum carmichaelii) and Cao Wu (草乌, Aconitum kusnezoffii), both classified as pregnancy-prohibited substances in the Chinese Pharmacopoeia. Aconitum alkaloids (primarily aconitine) are highly toxic and can be absorbed transdermally. Animal studies have shown that even moderate doses of raw Cao Wu can induce embryotoxicity, including growth retardation and cardiac developmental abnormalities. Additionally, the formula contains Ding Fen (定粉, lead powder), which poses a significant risk of lead exposure to the developing fetus. Chuan Shan Jia (穿山甲) is also traditionally listed as pregnancy-contraindicated due to its strong Blood-moving action. Pregnant women should not use this plaster under any circumstances.

Breastfeeding

Not recommended during breastfeeding. The formula contains Ding Fen (定粉, lead powder/lead carbonate), which poses a risk of lead transfer through breast milk even from topical absorption. Lead is a known neurotoxin with no safe threshold for infants. Additionally, aconitum alkaloids from Chuan Wu and Cao Wu can be absorbed through the skin and potentially transfer into breast milk. The nursing infant's immature liver and kidneys are poorly equipped to metabolize these toxic compounds. If topical pain relief or wound management is needed during lactation, safer alternatives should be used.

Children

Not suitable for use in infants or young children. Children have thinner skin and a higher skin-surface-area-to-body-weight ratio, which significantly increases the risk of transdermal absorption of toxic compounds, particularly aconitum alkaloids (from Chuan Wu and Cao Wu) and lead (from Ding Fen). Even in older children and adolescents, this plaster should only be used under close supervision by a qualified practitioner, with reduced application area and shorter duration of use. The plaster should never be applied near the face, hands, or any area the child might touch and then put in the mouth. If any signs of skin irritation, numbness, or systemic symptoms (nausea, dizziness, palpitations) occur, the plaster should be removed immediately.

Drug Interactions

If you are taking pharmaceutical medications, be aware of these potential interactions with Wan Ying Gao

Cardiac medications: Chuan Wu (川乌) and Cao Wu (草乌) contain aconitine and related alkaloids, which are potent cardiotoxins that can cause cardiac arrhythmias. Even with topical application, transdermal absorption could theoretically interact with antiarrhythmic drugs (such as amiodarone, digoxin, or beta-blockers), potentially amplifying cardiac effects. Patients on cardiac medications should avoid this formula.

Anticoagulants and antiplatelet agents: The formula contains several Blood-invigorating herbs (Dang Gui, Chi Shao, Da Huang, Chuan Shan Jia) that promote circulation. While topical absorption is limited, concurrent use with warfarin, heparin, or antiplatelet drugs like aspirin or clopidogrel warrants caution, particularly when the plaster is applied over large areas or on broken skin.

Lead-related concerns: Ding Fen (定粉, lead carbonate) in the formula means that any systemic lead absorption could interfere with the metabolism or efficacy of various pharmaceuticals. Lead can affect renal function and alter drug clearance. This is particularly concerning with nephrotoxic drugs or drugs with narrow therapeutic windows.

Usage Guidance

Practical advice for getting the most out of Wan Ying Gao

Best time to take

Apply the warmed plaster directly to the affected area after cleaning the skin. Can be applied at any time of day, though evening application before rest may enhance local absorption due to reduced movement.

Typical duration

Applied externally as needed, typically changed every 1-3 days per application, with a course of treatment lasting 1-4 weeks depending on the condition. Reassess if no improvement after 7 days.

Dietary advice

While using this plaster, avoid cold and raw foods, excessive alcohol, and greasy or heavily spiced dishes, as these can impair the body's ability to resolve toxins and heal wounds. Foods that support Qi and Blood circulation are beneficial, such as lightly cooked vegetables, lean proteins, and warming soups. If the plaster is being used for sores or abscesses, also avoid shellfish, lamb, and other foods traditionally considered to aggravate skin conditions (known as 发物, 'triggering foods' in Chinese dietary theory).

Wan Ying Gao originates from Yi Zong Jin Jian (《医宗金鉴》), Volume 62 Qīng dynasty, 1742 CE

Classical Texts

Key passages from the classical Chinese medical texts that first described Wan Ying Gao and its clinical use

Source: 《青囊秘传》(Qīng Náng Mì Chuán, Secret Transmission of the Green Bag)

The original text records this formula under the indication: 「治痈疽发背,对口诸疮,痰核流注」 ("Treats abscesses and deep-rooted sores on the back, matched-mouth sores and various ulcers, phlegm nodules and deep-flowing abscesses.") This indicates the formula was designed as a broadly applicable external plaster for serious surgical conditions where toxin has accumulated, Qi and Blood are obstructed, and the body's healing process has stalled.

Historical Context

How Wan Ying Gao evolved over the centuries — its origins, lineage, and place in the broader tradition of Chinese medicine

Wan Ying Gao (万应膏, "Universally Effective Plaster") is recorded in the Qing Nang Mi Chuan (《青囊秘传》, "Secret Transmission of the Green Bag"), a Qing dynasty text on external medicine (外科). The name "Qing Nang" (Green Bag) is itself a classical literary allusion to medical knowledge, tracing back to the legendary physician Hua Tuo of the late Han dynasty, who reportedly entrusted his medical writings in a green cloth bag. The formula's name, meaning "universally effective," reflects the ambitious scope typical of many classical plaster formulas, which were designed to address a wide range of surgical conditions with a single preparation.

The formula belongs to the rich tradition of Chinese medicated plasters (膏药), which became increasingly sophisticated during the Ming and Qing dynasties. Plaster-making was considered a specialized art in Chinese external medicine, requiring careful oil-extraction of herbs, precise temperature control when adding lead oxide (广丹/铅丹) to form the adhesive base, and skilled spreading onto cloth. A related formula, Wan Ying Ling Gao (万应灵膏, "Universally Effective Miraculous Plaster"), also appears in the same text with a partially overlapping but distinct composition, showing how practitioners developed families of related plasters for different clinical emphases. Over time, numerous variants bearing the "Wan Ying" name have appeared, including modern commercial preparations that differ substantially from the classical formula. Note that the classical formula contains Chuan Shan Jia (穿山甲, pangolin scales), now a prohibited ingredient due to wildlife conservation laws, and Ding Fen (定粉, lead powder), which raises modern toxicological concerns.