Shi Wei San

Pyrrosia Leaf Powder · 石韦散

Also known as: Shi Wei Yin (石韦饮, Pyrrosia Leaf Drink)

A classical formula used to clear heat from the urinary tract, promote smooth urination, and help dissolve urinary stones. It addresses painful, difficult, or frequent urination caused by heat accumulating in the Bladder, and is particularly suited for conditions involving urinary gravel or stones, cloudy urine, or lower abdominal pain during urination.

Origin Tai Ping Hui Min He Ji Ju Fang (太平惠民和剂局方) — Sòng dynasty, ~1078-1151 CE
Composition 11 herbs
Shi Wei
King
Shi Wei
Hua Shi
Deputy
Hua Shi
Qu Mai
Deputy
Qu Mai
Dong Kui Zi
Deputy
Dong Kui Zi
Mu Tong
Assistant
Mu Tong
Che Qian Zi
Assistant
Che Qian Zi
Bai Shao
Assistant
Bai Shao
Bai Zhu
Assistant
Bai Zhu
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Educational content Consult qualified TCM practitioners for diagnosis and treatment

Patterns Addressed

In TCM, symptoms don't appear randomly — they cluster into recognizable patterns of disharmony that reveal what's out of balance in the body. Shi Wei San is designed to correct these specific patterns.

Why Shi Wei San addresses this pattern

This is the primary pattern Shi Wei San addresses. When Damp-Heat accumulates in the Bladder, it disrupts the Bladder's Qi transformation function, leading to difficult, painful, and frequent urination. The Heat concentrates fluids, which may form gravel or stones, while the Dampness creates heaviness and fullness in the lower abdomen. Shi Wei San directly clears this Damp-Heat through multiple diuretic and Heat-clearing herbs (Shi Wei, Hua Shi, Qu Mai, Che Qian Zi, Mu Tong), while Dong Kui Zi and Wang Bu Liu Xing help unblock obstructions. The formula drains the pathogen downward and out through increased urination.

A practitioner would look for one or more of these signs

Painful Urination

Burning or stinging pain during urination, the hallmark symptom

Frequent Urination

Urgent need to urinate frequently with small volumes passed each time

Urinary Difficulty

Dribbling, incomplete voiding, or blocked urinary flow

Lower Abdominal Pain

Cramping or distending pain below the navel, worsening with a full bladder

Dark Urine

Urine that is dark yellow, turbid, or reddish

Blood In Urine

May appear in severe cases when Heat damages Blood vessels

Commonly Prescribed For

These conditions can arise from the patterns above. A practitioner would consider Shi Wei San when these conditions are specifically caused by those patterns — not for all cases of these conditions.

Arises from: Damp-Heat

TCM Interpretation

In TCM, kidney stones fall under the category of 'stone stranguria' (shi lin, 石淋). The formation of stones is understood as the result of prolonged Damp-Heat accumulating in the lower Burner. Heat 'steams' and concentrates the body's fluids, while Dampness provides the stagnant environment in which minerals coalesce into solid masses. Over time, Kidney Qi deficiency may also contribute: when the Kidneys cannot properly transform and move fluids, stagnation worsens. The stones themselves then cause further obstruction and pain, creating a vicious cycle of Heat, stagnation, and damage to the urinary passages.

Why Shi Wei San Helps

Shi Wei San targets the root mechanism of stone formation by clearing the Damp-Heat that concentrates minerals and creating an environment favorable for stone passage. Shi Wei and Hua Shi together are a classical pair for dissolving urinary gravel. Dong Kui Zi and Wang Bu Liu Xing smooth and open the urinary passages, facilitating the physical movement of stones downward. Che Qian Zi and Mu Tong increase urine volume, helping to flush smaller stones and debris. The Blood-moving herbs (Wang Bu Liu Xing, Dang Gui) address the secondary Blood stasis caused by stones irritating the urinary tract lining. Clinical research has shown that Shi Wei San with modifications achieved a total effective rate of over 93% in treating kidney stones over an 8-week course.

Also commonly used for

Bladder Worms

Stones in the lower urinary tract

Painful Urination

Dysuria from various causes with Heat signs

Blood In Urine

Hematuria associated with urinary Heat

Urinary Difficulty

Stranguria or difficult urination with Damp-Heat

Nephritis

When presenting with Damp-Heat pattern signs

Chronic Nephritis

As supportive treatment when Damp-Heat signs are present

What This Formula Does

Every TCM formula has a specific set of actions — here's what Shi Wei San does in the body, explained in both everyday and TCM terms

Therapeutic focus

In practical terms, Shi Wei San is primarily used to support these areas of health:

TCM Actions

In TCM terminology, these are the specific therapeutic actions that Shi Wei San performs to restore balance in the body:

How It Addresses the Root Cause

TCM doesn't just suppress symptoms — it aims to resolve the underlying imbalance. Here's how Shi Wei San works at the root level.

Shi Wei San addresses a pattern where Damp-Heat accumulates in the Urinary Bladder, disrupting its function of storing and excreting urine. In TCM theory, the Urinary Bladder works through a process called Qi transformation (气化, qi hua), which depends on clear, unobstructed flow. When Dampness and Heat lodge together in the Lower Burner, they "steam" and condense the body's fluids, much like sediment forming in stagnant, overheated water.

This Damp-Heat can produce several forms of painful urination (lin zheng, 淋证). In heat stranguria (热淋), the Heat scorches the urinary tract, causing burning, scanty, dark urine. In stone stranguria (石淋), the prolonged brewing of Damp-Heat causes minerals in the urine to crystallize and form sandy deposits or stones. In blood stranguria (血淋), the Heat damages the small blood vessels of the urinary tract, causing blood to appear in the urine. In all these cases, the root cause is the same: Damp-Heat obstructing the Bladder's Qi transformation, blocking the free flow of urine, and potentially injuring the local tissue.

The formula works by clearing Heat to remove the thermal component, promoting urination to flush out the Dampness and any accumulated sediment, and restoring the Bladder's normal Qi transformation so that urine flows freely and painlessly again.

Formula Properties

Every formula has an inherent temperature, taste, and affinity for specific organs — these properties determine how it interacts with the body

Overall Temperature

Cool

Taste Profile

Predominantly bitter and bland with a mild sweet note. Bitter to clear Heat and drain Dampness, bland to promote urination and leach out turbidity from the Lower Burner.

Channels Entered

Bladder Lung Small Intestine Kidney

Ingredients

11 herbs

The herbs that make up Shi Wei San, organized by their role in the prescription

King — Main ingredient driving the formula
Deputy — Assists and enhances the King
Assistant — Supports or moderates other herbs
Envoy — Directs the formula to its target
King — Main ingredient driving the formula
Shi Wei

Shi Wei

Pyrrosia leaf

Dosage 6 - 10g
Temperature Slightly Cool
Taste Sweet (甘 gān), Bitter (苦 kǔ)
Organ Affinity Lungs, Urinary Bladder
Preparation Remove the back hairs (去毛) before use

Role in Shi Wei San

The chief herb that clears Damp-Heat from the Bladder, promotes urination, unblocks painful urinary dysfunction, and helps dissolve urinary stones. Its cool nature directly targets the Heat in the Bladder that drives the pattern.
Deputies — Assists and enhances the King
Hua Shi

Hua Shi

Talc

Dosage 6 - 10g
Temperature Cold
Taste Sweet (甘 gān), Bland (淡 dàn)
Organ Affinity Stomach, Urinary Bladder

Role in Shi Wei San

Strongly clears Heat and promotes urination through its slippery nature, helping to flush sand and stones from the urinary tract. Works synergistically with Shi Wei to form the primary stone-dissolving pair.
Qu Mai

Qu Mai

Fringed pink herb

Dosage 9 - 12g
Temperature Cold
Taste Bitter (苦 kǔ)
Organ Affinity Heart, Small Intestine, Urinary Bladder

Role in Shi Wei San

Clears Heat from the Heart and Small Intestine, promotes urination, and unblocks painful urinary dysfunction. Reinforces the formula's ability to clear Heat from the lower urinary tract.
Dong Kui Zi

Dong Kui Zi

Mallow seed

Dosage 9 - 12g
Temperature Cold
Taste Sweet (甘 gān)
Organ Affinity Large Intestine, Small Intestine, Urinary Bladder

Role in Shi Wei San

Moistens and smooths the urinary passages, promotes urination, and helps unblock obstructions in the Bladder. Its slippery quality facilitates the passage of gravel and stones.
Assistants — Supports or moderates other herbs
Mu Tong

Mu Tong

Akebia stem

Dosage 3 - 6g
Temperature Cold
Taste Bitter (苦 kǔ)
Organ Affinity Heart, Small Intestine, Urinary Bladder

Role in Shi Wei San

Drains Heat from the Heart via the Small Intestine into the Bladder, promotes urination, and unblocks the water passages. Connects the upper and lower Burners to ensure complete drainage of Heat.
Che Qian Zi

Che Qian Zi

Plantain Seed

Dosage 9 - 12g
Temperature Cold
Taste Sweet (甘 gān)
Organ Affinity Liver, Kidneys, Lungs, Small Intestine
Preparation Wrap in cloth bag (包煎) when used in decoction

Role in Shi Wei San

Clears Heat and promotes urination, helping to flush Damp-Heat from the Bladder. Also clears the Liver and brightens the eyes as a secondary benefit.
Bai Shao

Bai Shao

White peony root

Dosage 9 - 12g
Temperature Slightly Cool
Taste Bitter (苦 kǔ), Sour (酸 suān)
Organ Affinity Liver, Spleen

Role in Shi Wei San

Nourishes Blood and softens the Liver, alleviates the cramping abdominal pain that accompanies urinary obstruction. Its sour-astringent quality prevents excessive drainage of Yin fluids from the many diuretic herbs.
Bai Zhu

Bai Zhu

White Atractylodes rhizome

Dosage 9 - 12g
Temperature Warm
Taste Bitter (苦 kǔ), Sweet (甘 gān)
Organ Affinity Spleen, Stomach

Role in Shi Wei San

Strengthens the Spleen and promotes water metabolism, ensuring the body's fluid processing remains efficient. Protects the Spleen from damage by the formula's many cold, draining herbs.
Dang Gui

Dang Gui

Chinese Angelica root

Dosage 6 - 10g
Temperature Warm
Taste Sweet (甘 gān), Acrid / Pungent (辛 xīn)
Organ Affinity Liver, Heart, Spleen

Role in Shi Wei San

Nourishes and invigorates Blood, alleviating pain from Blood stasis that may accompany prolonged urinary obstruction. Prevents the cold, draining herbs from consuming Blood.
Wang Bu Liu Xing

Wang Bu Liu Xing

Cowherb seed

Dosage 6 - 10g
Temperature Neutral
Taste Bitter (苦 kǔ)
Organ Affinity Liver, Stomach

Role in Shi Wei San

Invigorates Blood circulation and promotes urination. Its ability to 'go everywhere without staying' helps push stagnant material through the urinary passages and assists in expelling stones.
Envoy — Directs the formula to its target
Gan Cao

Gan Cao

Licorice root

Dosage 3 - 6g
Temperature Neutral
Taste Sweet (甘 gān)
Organ Affinity Heart, Lungs, Spleen, Stomach
Preparation Honey-prepared (炙)

Role in Shi Wei San

Harmonizes all the herbs in the formula, moderates the cold and draining properties of the other ingredients, and alleviates urinary pain. Used in its honey-prepared form (炙甘草) to protect the Stomach.

Why This Combination Works

How the herbs in Shi Wei San complement each other

Overall strategy

This formula addresses Bladder Heat with urinary obstruction, a condition where Heat accumulates in the lower urinary tract, causing painful, difficult, and frequent urination that may also involve the passage of stones or gravel. The prescription strategy combines strong Heat-clearing and urination-promoting herbs with Blood-nourishing and Spleen-strengthening agents to ensure the pathogenic Heat is drained without damaging the body's vital substances.

King herbs

Shi Wei (Pyrrosia leaf) serves as the King herb. It enters the Bladder channel, directly clears Damp-Heat from the urinary tract, promotes urination, and is especially effective at helping dissolve and expel urinary stones. Its cool nature and diuretic power make it the ideal lead herb for any form of painful urinary dysfunction (lin zheng).

Deputy herbs

Hua Shi (Talcum) powerfully clears Heat and promotes urination with its slippery nature, physically helping to flush sand and gravel from the urinary passages. Qu Mai (Dianthus) clears Heat from the Heart and Small Intestine and drives it downward through the Bladder. Dong Kui Zi (Mallow seed) moistens and smooths the urinary passages, reducing friction and blockage. Together, these three Deputies amplify the King herb's ability to clear Heat, promote urination, and expel stones.

Assistant herbs

Several Assistants serve different purposes. Mu Tong and Che Qian Zi are reinforcing Assistants that further promote urination and clear Heat. Bai Shao and Dang Gui are restraining Assistants: they nourish Blood and Yin, preventing the many cold and draining herbs from consuming the body's fluids and Blood. Bai Shao additionally relieves the cramping lower abdominal pain that accompanies stranguria. Bai Zhu strengthens the Spleen to support water metabolism and protect against the damage that cold, draining herbs can inflict on digestive function. Wang Bu Liu Xing invigorates Blood and promotes the passage of material through the urinary tract, acting as a reinforcing Assistant that targets Blood stasis from chronic obstruction.

Envoy herbs

Gan Cao (Licorice, honey-prepared) harmonizes all the herbs, moderates the cold properties of the formula, and helps relieve urinary tract pain. It guides the formula's actions to work together smoothly.

Notable synergies

The pairing of Shi Wei with Hua Shi creates a powerful stone-dissolving combination: Shi Wei clears the Heat that concentrates minerals, while Hua Shi's slippery nature helps physically flush debris. The pairing of Bai Shao with Dang Gui protects Blood and Yin, ensuring the formula can be used over a treatment course without depleting the patient. Mu Tong and Qu Mai together create a top-to-bottom drainage pathway, clearing Heat from the Heart channel down through the Small Intestine and into the Bladder for excretion.

How to Prepare

Traditional preparation instructions for Shi Wei San

Grind all ten ingredients into a fine powder. Take 6g (approximately two qian) per dose, mixed with a decoction of wheat (小麦汤) or plain warm water. Take before meals, two to three times daily.

Alternatively, the formula may be prepared as a decoction using proportionally reduced dosages of each herb. Decoct in water for approximately 30 minutes, strain, and take warm before meals.

Common Modifications

How practitioners adapt Shi Wei San for specific situations

Added
Jin Qian Cao

30g, strongly dissolves stones and promotes their expulsion

Hai Jin Sha

15g, clears Heat from the urinary tract and helps dissolve stones

Ji nei jin

10g, dissolves calcifications and hardened accumulations

These three stone-dissolving herbs (collectively known as 'three golds') powerfully reinforce the formula's ability to break down and expel urinary calculi.

Educational content — always consult a qualified healthcare provider or TCM practitioner before using any herbal formula.

Contraindications

Situations where Shi Wei San should not be used or requires extra caution

Caution

Yin deficiency with depleted fluids. This formula is cooling and draining in nature, so it should not be used when the underlying problem is fluid depletion rather than Damp-Heat accumulation.

Avoid

Cold-type urinary difficulty due to Kidney Yang deficiency. The formula is designed for Heat-pattern stranguria and would worsen cold conditions with clear, copious urine and cold limbs.

Caution

Spleen and Stomach deficiency with chronic loose stools. The cold and draining nature of the herbs can further weaken digestive function.

Avoid

Pregnancy. Several herbs in this formula (notably Qu Mai/Dianthus and Hua Shi/Talcum) have traditionally been cautioned against during pregnancy due to their strong downward-draining and slippery nature.

Special Populations

Important considerations for pregnancy, breastfeeding, and pediatric use

Pregnancy

Contraindicated during pregnancy. Qu Mai (Dianthus, 瞿麦) has traditionally been classified as a pregnancy-prohibited herb because it can stimulate uterine contractions and promote menstrual flow. Hua Shi (Talcum, 滑石) has a strongly slippery, downward-draining quality that classical texts caution against in pregnancy. Wang Bu Liu Xing (Vaccaria seed), if included in the expanded version, is also explicitly contraindicated in pregnancy due to its Blood-moving properties. This formula should be avoided entirely during pregnancy.

Breastfeeding

No specific contraindications for breastfeeding have been documented for this formula. The herbs are primarily cooling and draining, and their effects are focused on the urinary system. However, because the formula is designed for acute Damp-Heat conditions and has a cold, draining nature, prolonged use during breastfeeding should be avoided as it could theoretically affect the mother's fluid balance and milk production. Short-term use under practitioner guidance is generally considered acceptable.

Children

This formula can be used in children for acute urinary tract infections or urinary stones presenting with Damp-Heat signs, but dosages must be significantly reduced. A general guideline is one-third to one-half of the adult dose for children aged 6 to 12, and one-quarter for children under 6. The cold, draining nature of the formula means it should be used for the shortest effective duration in children, whose Spleen and Stomach Qi is inherently delicate. Practitioners should monitor for any digestive upset. Not suitable for infants without specialist supervision.

Drug Interactions

If you are taking pharmaceutical medications, be aware of these potential interactions with Shi Wei San

Diuretic medications: This formula has significant diuretic effects. Concurrent use with pharmaceutical diuretics (such as furosemide or hydrochlorothiazide) may potentiate fluid and electrolyte loss, increasing the risk of dehydration and electrolyte imbalances.

Lithium: Because the formula strongly promotes urination, it could theoretically alter lithium excretion and affect serum lithium levels. Patients on lithium therapy should be monitored closely.

Anticoagulant and antiplatelet drugs: The Qian Jin Fang version of Shi Wei San includes Dang Gui and Pu Huang, both of which have mild blood-moving properties. If this version is used alongside anticoagulants (warfarin, heparin) or antiplatelet agents (aspirin, clopidogrel), there may be an increased risk of bleeding.

Usage Guidance

Practical advice for getting the most out of Shi Wei San

Best time to take

Between meals, 2-3 times daily. Can also be taken on an empty stomach with warm water for stronger diuretic effect.

Typical duration

Acute use: 3-10 days for urinary tract infections or acute stone episodes. Reassess if symptoms persist beyond 10 days.

Dietary advice

While taking this formula, drink plenty of warm water to support its diuretic action and help flush out urinary sediment and Heat. Avoid greasy, fried, and heavily spiced foods, which can generate more Dampness and Heat. Reduce intake of alcohol, strong tea, and coffee, which irritate the urinary tract. Foods that gently support urinary health are beneficial, such as barley water (yi mi shui), watermelon, winter melon, and corn silk tea. Avoid cold and raw foods if the digestion is weak, as the formula is already cooling in nature.

Shi Wei San originates from Tai Ping Hui Min He Ji Ju Fang (太平惠民和剂局方) Sòng dynasty, ~1078-1151 CE

Classical Texts

Key passages from the classical Chinese medical texts that first described Shi Wei San and its clinical use

From the Qian Jin Yao Fang (千金要方, Prescriptions Worth a Thousand Gold):

The earliest recorded Shi Wei San appears in Sun Simiao's Qian Jin Yao Fang, with the composition: Shi Wei (石韦), Dang Gui (当归), Pu Huang (蒲黄), and Shao Yao (芍药) in equal parts, ground to powder and taken with wine. This version was specifically indicated for blood stranguria (血淋, xue lin).


From the Ben Cao Chong Yuan (本草崇原):

"石韦,主治劳热邪气者,劳热在骨,邪气在皮,肺肾之所主也。"

"Shi Wei treats taxation Heat and pathogenic Qi. Taxation Heat resides in the bones, pathogenic Qi in the skin, both governed by the Lungs and Kidneys."


From the Shen Nong Ben Cao Jing (神农本草经):

"主劳热邪气,五癃闭不通,利小便水道。"

"It governs taxation Heat and pathogenic Qi, the five types of urinary obstruction and blockage, and frees the urinary water passages."

Historical Context

How Shi Wei San evolved over the centuries — its origins, lineage, and place in the broader tradition of Chinese medicine

The name "Shi Wei San" (石韦散, Pyrrosia Powder) has been applied to several distinct formulas across Chinese medical history, all sharing the chief herb Shi Wei (Pyrrosia leaf) but differing in composition and indication.

The earliest version appears in Sun Simiao's Qian Jin Yao Fang (Prescriptions Worth a Thousand Gold, 7th century Tang Dynasty). This four-herb formula of Shi Wei, Dang Gui, Pu Huang, and Shao Yao was designed specifically for blood stranguria, combining urinary-clearing herbs with Blood-nourishing and hemostatic agents. A simpler two-herb version (Shi Wei with Hua Shi) was recorded in the Gu Jin Lu Yan Fang (Ancient and Modern Effective Prescriptions) for stone stranguria. The more elaborate five-herb version adding Dong Kui Zi, Qu Mai, and Che Qian Zi became the standard formula in Song Dynasty compilations such as the Taiping Sheng Hui Fang, broadening its scope to treat both heat and stone stranguria.

Shi Wei itself has a long pedigree, first appearing in the Shen Nong Ben Cao Jing (Divine Farmer's Classic, late Western Han Dynasty), where it was praised for its ability to "open the water passages" and treat "five types of urinary obstruction." Later materia medica texts noted an interesting folk criterion for quality: the Ming Yi Bie Lu stated that Shi Wei growing on rocks "where it cannot hear the sound of water or human voices" (不闻水声及人声者良) was considered the best quality, reflecting an ancient belief that herbs absorb qualities from their environment.