Jie Geng Tang

Platycodon Decoction · 桔梗湯

Also known as: Gan Jie Tang (甘桔汤), Ru Sheng Tang (如圣汤), Jie Geng Gan Cao Tang (桔梗甘草汤)

A simple, classical two-herb formula used to soothe sore throats and help the lungs expel phlegm and pus. It combines Platycodon root to open the airways and benefit the throat with raw Licorice root to clear heat, relieve pain, and reduce inflammation. It is the foundational prescription for throat pain in Chinese medicine and is often used as a base to which other herbs are added.

Origin Shang Han Lun (伤寒论) by Zhang Zhongjing, also recorded in Jin Gui Yao Lue (金匮要略) — Hàn dynasty, ~200 CE
Composition 2 herbs
Jie Geng
King
Jie Geng
Gan Cao
Deputy
Gan Cao
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Educational content Consult qualified TCM practitioners for diagnosis and treatment

Patterns Addressed

In TCM, symptoms don't appear randomly — they cluster into recognizable patterns of disharmony that reveal what's out of balance in the body. Jie Geng Tang is designed to correct these specific patterns.

Why Jie Geng Tang addresses this pattern

When pathogenic Heat or Fire rises along the Shaoyin channel (which passes through the throat), it causes swelling, pain, and obstruction in the pharynx. This is the primary pattern described in the Shang Han Lun clause 311: a Shaoyin-stage sore throat where Heat has accumulated but the condition is not yet deeply cold or deficient. Jie Geng opens the Lung Qi to relieve the obstruction and disperse the accumulated Heat from the throat, while raw Gan Cao directly clears Heat-toxin and soothes the inflamed tissue. The formula is indicated when simple Gan Cao alone (Gan Cao Tang) has failed, suggesting the Heat has become more entrenched, possibly with phlegm or early pus formation complicating the picture.

A practitioner would look for one or more of these signs

Throat Pain

Sore throat with swelling and difficulty swallowing

Tonsil Swelling

Red, swollen tonsils or pharynx

Hoarseness

Hoarse or lost voice

Commonly Prescribed For

These conditions can arise from the patterns above. A practitioner would consider Jie Geng Tang when these conditions are specifically caused by those patterns — not for all cases of these conditions.

Arises from: Heat Toxin Attacking the Throat

TCM Interpretation

In TCM, a sore throat (咽痛) can arise from many different root causes. The type of sore throat that Jie Geng Tang addresses involves Heat or Fire rising upward along channels that pass through the throat (particularly the Shaoyin Kidney and Heart channels). This Heat may come from an external pathogenic invasion (like a cold or flu) that has progressed inward, or from internal Heat that flares up toward the throat. The key signs are a red, swollen, painful throat, possibly with sticky phlegm or early signs of pus, where the condition is too stubborn for simple Heat-clearing alone. The Lung governs the throat and voice, so when Lung Qi is obstructed by Heat and phlegm, the throat becomes painful and the voice may be affected.

Why Jie Geng Tang Helps

Jie Geng Tang addresses sore throat from two angles simultaneously. Jie Geng opens and ventilates the Lung Qi, relieving the obstruction at the throat. It has a natural affinity for the Upper Burner and is specifically indicated for throat and Lung conditions. Raw Gan Cao clears Heat-toxin and directly soothes inflamed, painful tissue. The pairing is considered the foundational prescription for Heat-type sore throat in Chinese medicine. It is often used as a base to which other herbs are added depending on the specific presentation.

Also commonly used for

Tonsil Swelling

Tonsillitis with swelling and pain

Hypochondrial Pain That Is Worse On Coughing And Breathing

Laryngeal cough (throat-origin cough) and post-cold cough

Hoarseness

Voice loss or hoarseness due to throat inflammation

Bronchiectasis

Bronchiectasis with purulent sputum

Acute Bronchitis

Acute bronchitis with productive cough and sore throat

What This Formula Does

Every TCM formula has a specific set of actions — here's what Jie Geng Tang does in the body, explained in both everyday and TCM terms

Therapeutic focus

In practical terms, Jie Geng Tang is primarily used to support these areas of health:

TCM Actions

In TCM terminology, these are the specific therapeutic actions that Jie Geng Tang performs to restore balance in the body:

How It Addresses the Root Cause

TCM doesn't just suppress symptoms — it aims to resolve the underlying imbalance. Here's how Jie Geng Tang works at the root level.

Jie Geng Tang addresses two closely related pathological situations rooted in the Lung system. In both scenarios, the core problem is Heat-toxin lodging in the upper body, particularly the throat and Lungs, obstructing the normal descending and dispersing functions of Lung Qi.

In the Shaoyin sore throat pattern described in the Shang Han Lun, a febrile illness has progressed to affect the Shaoyin level. Heat-toxin flares upward along the Kidney channel to the throat (the Kidney channel runs through the throat in TCM anatomy). The throat becomes inflamed and painful. This is not a simple exterior Wind-Heat invasion but a deeper-level Heat that has settled in the Shaoyin, which is why Zhang Zhongjing first tries Gan Cao Tang alone, and escalates to Jie Geng Tang only if the simpler approach fails. The addition of Jie Geng opens the Lung Qi and directs therapeutic action upward to the throat, while Gan Cao clears Heat-toxin and soothes the inflamed tissue.

In the Lung Abscess (肺痈) pattern described in the Jin Gui Yao Lue, Heat-toxin has festered within the Lungs over time, causing tissue breakdown with accumulation of pus. The signs are characteristic: coughing with chest fullness (obstructed Lung Qi), a rapid pulse with chills (Heat struggling with the body's defenses), a dry throat without thirst (Heat damaging local fluids but not yet consuming systemic Yin), and the hallmark expulsion of foul-smelling, purulent sputum resembling rice porridge. Here the formula works by opening the Lung Qi to expel the pus outward and downward, while the sweet, cooling Gan Cao detoxifies and supports the body's ability to resolve the abscess.

Formula Properties

Every formula has an inherent temperature, taste, and affinity for specific organs — these properties determine how it interacts with the body

Overall Temperature

Neutral

Taste Profile

Predominantly sweet and slightly bitter: sweet from Gan Cao to harmonize and detoxify, bitter and slightly acrid from Jie Geng to open and disperse the Lung Qi.

Target Organs

Channels Entered

Ingredients

2 herbs

The herbs that make up Jie Geng Tang, organized by their role in the prescription

King — Main ingredient driving the formula
Deputy — Assists and enhances the King
King — Main ingredient driving the formula
Jie Geng

Jie Geng

Platycodon roots

Dosage 3 - 6g
Temperature Neutral
Taste Bitter, Pungent
Organ Affinity Lungs

Role in Jie Geng Tang

Opens and diffuses Lung Qi, benefits the throat, expels phlegm, and promotes the discharge of pus. As the classical commentator Xu Hong noted, Jie Geng serves as the sovereign because it floats upward to treat the Upper Burner, acting as a 'boat' to carry the formula's action to the throat and Lungs.
Deputy — Assists and enhances the King
Gan Cao

Gan Cao

Liquorice

Dosage 6 - 12g
Temperature Neutral
Taste Sweet
Organ Affinity Heart, Lungs, Spleen, Stomach
Preparation Use raw (Sheng Gan Cao 生甘草), not honey-processed

Role in Jie Geng Tang

Raw Gan Cao (Sheng Gan Cao) clears Heat, resolves toxins, soothes the throat, and relieves pain. Used at double the dose of Jie Geng, it is the primary Heat-clearing and detoxifying agent in this formula. It also harmonizes the formula and protects the Stomach from Jie Geng's potential to cause nausea.

Why This Combination Works

How the herbs in Jie Geng Tang complement each other

Overall strategy

Jie Geng Tang uses a simple two-herb pairing to open the Lung Qi pathway upward toward the throat while simultaneously clearing Heat and toxins from the area. The formula addresses throat pain caused by Heat accumulating in the upper body, and also treats Lung abscess by promoting the expulsion of pus and phlegm.

King herb

Jie Geng (Platycodon root) is the King herb. Its pungent and bitter flavour opens and lifts Lung Qi, directs the formula's action to the throat and Upper Burner, expels phlegm, and promotes pus drainage. Classical commentators describe it as acting like a boat (舟楫) that carries therapeutic action upward to the throat and chest. In the Shang Han Lun context, when Gan Cao alone fails to resolve throat pain, Jie Geng is added precisely because the condition has progressed to involve phlegm obstruction or early pus formation that requires active opening and dispersing.

Deputy herb

Raw Gan Cao (Glycyrrhiza root, unprocessed) is the Deputy. Despite being present at twice the dose of Jie Geng, its role is supportive: it clears Heat, resolves toxins, soothes inflammation, and relieves the acute pain of the sore throat. The sweet flavour of Gan Cao also moderates and harmonizes Jie Geng's dispersing action, preventing excessive upward scattering of Qi. Importantly, raw Gan Cao (not honey-processed) is specified because the raw form has stronger Heat-clearing and detoxifying properties.

Notable synergies

The Jie Geng and Gan Cao pairing is one of the most celebrated herb combinations in Chinese medicine. Jie Geng opens, lifts, and disperses, while Gan Cao clears, soothes, and anchors. Together they create a balanced action: one herb pushes outward and upward to expel pathogenic factors, while the other pulls inward to calm inflammation and protect healthy tissue. This complementary dynamic of dispersing and consolidating (一宣一清) is why the pair became the foundational building block for countless later throat and Lung formulas.

How to Prepare

Traditional preparation instructions for Jie Geng Tang

Place both herbs in a pot with approximately 600 ml of water. Bring to a boil, then reduce to a gentle simmer and cook until roughly 200-300 ml of liquid remains. Strain and discard the dregs. Divide the decoction into two portions and drink warm.

The original text states: "Take the two herbs, add three sheng of water, boil down to one sheng, remove the dregs, and drink warm in two divided doses" (上二味,以水三升,煮取一升,去滓,温分再服). For sore throat conditions, sipping the decoction slowly allows prolonged contact with the affected area and can improve efficacy.

Common Modifications

How practitioners adapt Jie Geng Tang for specific situations

Added
Xuan Shen

9-15g, clears Heat and benefits the throat

She Gan

6-9g, clears Heat-toxin from the throat and reduces swelling

Niu Bang Zi

6-9g, disperses Wind-Heat and soothes the throat

For more severe throat swelling and pain, adding strongly throat-targeted Heat-clearing herbs reinforces the formula's ability to resolve toxin and reduce local inflammation.

Educational content — always consult a qualified healthcare provider or TCM practitioner before using any herbal formula.

Contraindications

Situations where Jie Geng Tang should not be used or requires extra caution

Avoid

Yin deficiency with chronic dry cough and coughing of blood. Jie Geng's ascending and dispersing nature can further deplete Yin fluids and worsen bleeding.

Caution

Liver Yang rising with dizziness and headache. The upward-directing nature of Jie Geng may aggravate ascending Yang symptoms.

Caution

Stomach Qi rebellion with nausea and vomiting. Both herbs act upward and may worsen nausea; excessive dosage of Jie Geng is known to cause vomiting.

Caution

Wind-Cold patterns without Heat signs. This formula's strength lies in clearing Heat-toxin from the throat and Lungs; a purely Cold presentation requires warming, dispersing formulas instead.

Caution

Patients with hypertension or edema, or those on potassium-depleting medications. Gan Cao (Licorice) in significant doses can cause pseudoaldosteronism with sodium and water retention.

Special Populations

Important considerations for pregnancy, breastfeeding, and pediatric use

Pregnancy

Use with caution during pregnancy. Classical sources note that Jie Geng (Platycodon root) is contraindicated for pregnant women due to its ascending, dispersing nature, which may theoretically disturb fetal Qi. Gan Cao (Licorice) in the large doses used in this formula (double that of Jie Geng) may contribute to fluid retention and elevated blood pressure, both of which are concerns during pregnancy. While neither herb is considered strongly abortifacient, this formula should only be used during pregnancy under the guidance of a qualified practitioner and only when clearly needed.

Breastfeeding

Generally considered compatible with breastfeeding when used at standard doses for short durations. Neither Jie Geng nor Gan Cao is known to produce harmful effects through breast milk at therapeutic doses. However, large or prolonged doses of Gan Cao may theoretically affect maternal fluid balance and electrolytes (due to its pseudoaldosterone effect), which could indirectly influence lactation. Interestingly, Jie Geng has a traditional reputation for promoting lactation in some classical sources. Consult a qualified practitioner before use during breastfeeding.

Children

Jie Geng Tang is suitable for pediatric use and has a long tradition of treating childhood sore throat and cough. For children, dosages should be reduced proportionally based on age and body weight. A general guideline: children aged 3-6 years may use approximately one-third of the adult dose; children aged 7-12 may use one-half. The formula's mild, two-herb composition makes it well-tolerated by children. However, excessive dosage of Jie Geng can cause nausea or vomiting, so careful dose titration is important in young patients. The decoction can be sweetened slightly for palatability given that Gan Cao already provides a sweet taste. Consult a pediatric TCM practitioner for specific dosing.

Drug Interactions

If you are taking pharmaceutical medications, be aware of these potential interactions with Jie Geng Tang

Gan Cao (Licorice root) interactions: Gan Cao is the dominant herb by weight in this formula (used at double the dose of Jie Geng), making its drug interactions clinically relevant.

  • Antihypertensives: Glycyrrhizin in Gan Cao can cause pseudoaldosteronism (sodium retention, potassium loss, fluid retention), potentially counteracting the effects of blood pressure-lowering medications.
  • Diuretics (especially potassium-wasting types such as furosemide or hydrochlorothiazide): Concurrent use may worsen potassium depletion, increasing the risk of hypokalemia, muscle weakness, and cardiac arrhythmias.
  • Cardiac glycosides (digoxin): Gan Cao-induced hypokalemia can increase sensitivity to digoxin, raising the risk of toxicity and dangerous arrhythmias.
  • Corticosteroids: Glycyrrhizin inhibits the enzyme 11-beta-hydroxysteroid dehydrogenase, potentially enhancing and prolonging the effects of corticosteroids and increasing the risk of side effects.
  • Warfarin and anticoagulants: Some licorice constituents may have mild effects on platelet aggregation; monitor INR if co-administered.

Jie Geng (Platycodon root): No major pharmaceutical drug interactions are well documented for Jie Geng at standard therapeutic doses. Its saponin content may theoretically affect the absorption of other orally administered medications, so it is prudent to separate dosing times.

Usage Guidance

Practical advice for getting the most out of Jie Geng Tang

Best time to take

Between meals, warm, in two divided doses per day (morning and evening). Taking on an empty or near-empty stomach enhances absorption and directs the formula's action upward to the throat and Lungs.

Typical duration

Acute use: 3-7 days for sore throat or early-stage cough; reassess if symptoms persist beyond one week.

Dietary advice

While taking this formula, avoid greasy, fried, and heavily spiced foods, which can generate Phlegm-Heat and worsen throat and Lung inflammation. Cold, raw foods and iced drinks should also be limited, as they can impair the Spleen's ability to transform fluids and may create more Phlegm. Alcohol and tobacco should be strictly avoided, as both directly irritate the throat and Lungs. Favor light, easy-to-digest foods such as congee, steamed vegetables, and pear soup, which moisten the Lungs and support recovery. Warm liquids like honey water or pear and lily bulb soup are particularly helpful.

Jie Geng Tang originates from Shang Han Lun (伤寒论) by Zhang Zhongjing, also recorded in Jin Gui Yao Lue (金匮要略) Hàn dynasty, ~200 CE

Classical Texts

Key passages from the classical Chinese medical texts that first described Jie Geng Tang and its clinical use

From the Shang Han Lun (Treatise on Cold Damage), chapter on Shaoyin disease:

「少阴病,二三日,咽痛者,可与甘草汤;不差,与桔梗汤。」

"In Shaoyin disease, after two or three days, if there is sore throat, one may give Gan Cao Tang (Licorice Decoction). If it does not improve, give Jie Geng Tang (Platycodon Decoction)."


From the Jin Gui Yao Lue (Essential Prescriptions of the Golden Cabinet), chapter on Lung Abscess:

「咳而胸满,振寒脉数,咽干不渴,时出浊唾腥臭,久久吐脓如米粥者,为肺痈,桔梗汤主之。」

"Coughing with chest fullness, shivering chills with a rapid pulse, dry throat without thirst, occasionally expectorating turbid, foul-smelling sputum, and over time spitting pus resembling rice porridge: this is Lung Abscess. Jie Geng Tang governs it."


Original preparation method:

「桔梗一两,甘草二两。上二味,以水三升,煮取一升,去滓,温分再服。」

"Jie Geng one liang, Gan Cao two liang. The above two ingredients: decoct in three sheng of water, reduce to one sheng, remove the dregs, and take warm in two divided doses."

Historical Context

How Jie Geng Tang evolved over the centuries — its origins, lineage, and place in the broader tradition of Chinese medicine

Jie Geng Tang is one of the simplest and most ancient formulas in Chinese medicine, containing only two herbs: Jie Geng (Platycodon root) and Gan Cao (Licorice root). It was recorded by Zhang Zhongjing in both the Shang Han Lun and the Jin Gui Yao Lue during the Eastern Han Dynasty (circa 200 CE), making it one of the earliest documented prescriptions. In the Shang Han Lun, it appears as a stepwise escalation from the even simpler Gan Cao Tang for Shaoyin-level sore throat. In the Jin Gui Yao Lue, it is prescribed for Lung Abscess (肺痈), with Gan Cao used at double the dose of Jie Geng.

Later generations came to refer to this formula interchangeably as Gan Jie Tang (甘桔汤, Licorice and Platycodon Decoction), and it was also known as Ru Sheng Tang (如圣汤, "Saintly Decoction") in the Tai Ping Hui Min He Ji Ju Fang (Song Dynasty imperial pharmacy formulary), reflecting the high esteem in which it was held for treating throat conditions. Its remarkable simplicity made it a foundational building block: many famous later formulas incorporated Jie Geng and Gan Cao as a core pairing for directing therapeutic action to the Lungs and throat. Notable examples include Yin Qiao San, Sang Ju Yin, and numerous pediatric cough syrups that still use these two herbs as their base.

Modern Research

4 published studies investigating the pharmacological effects or clinical outcomes of Jie Geng Tang

1

Protective effect of Jie-Geng-Tang against Staphylococcus aureus induced acute lung injury in mice (Preclinical study, 2019)

Liu Y, Hong Z, Qian J, Wang Y, Wang S. J Ethnopharmacol. 2019; 243: 112076.

This animal study found that pretreatment with Jie Geng Tang significantly improved lung tissue damage in mice with S. aureus-induced acute lung injury. The formula reduced bacterial load in the lungs and suppressed inflammatory markers (TNF-alpha, IL-1beta). Five active compounds from the formula showed direct antibacterial activity against S. aureus, including licochalcone A and isoliquiritigenin from the Licorice component.

2

Chemomics-Integrated Proteomics Analysis of Jie-Geng-Tang to Ameliorate Lipopolysaccharide-Induced Acute Lung Injury in Mice (Preclinical study, 2016)

Qian J, et al. Evid Based Complement Alternat Med. 2016; 2016: 7379235.

Using an integrated chemomics-proteomics approach, researchers identified 11 potential anti-inflammatory compounds in Jie Geng Tang, including derivatives of glycyrrhizic acid, licorice-saponin, liquiritin, and platycodigenin. The formula demonstrated protective effects against LPS-induced acute lung injury in mice, with mechanisms involving multiple protein targets and signaling pathways.

PubMed
3

Characterization of the chemical constituents of Jie-Geng-Tang and the metabolites in the serums and lungs of mice after oral administration by LC-Q-TOF-MS (Pharmacokinetic study, 2021)

Liu YN, Hu MT, Qian J, Wang Y, Wang SF. Chin J Nat Med. 2021; 19(4): 284-294.

This study characterized 96 chemical constituents in Jie Geng Tang, including flavonoids, triterpene saponins, and organic acids. After oral administration in mice, researchers tracked which compounds were absorbed into the bloodstream and which reached the lung tissue specifically, providing evidence for the formula's lung-targeting properties.

4

Phytochemical investigation of Jie-Geng-Tang and regulatory role in the TNF-alpha pathway in mitigating pulmonary fibrosis (Preclinical study, 2024)

Li B, Zhao R, Jiang X, Liu C, Ma Y, Zhang H. Naunyn Schmiedebergs Arch Pharmacol. 2024.

Researchers found that the ethanol extract of Jie Geng Tang significantly reduced fibrosis markers (alpha-SMA and collagen-I) and alleviated lung tissue damage in a bleomycin-induced pulmonary fibrosis mouse model. Key active flavonoids including apigenin, kaempferol, and quercetin were identified, acting through the TNF-alpha signaling pathway.

Research on TCM formulas is growing but still limited by Western clinical trial standards. These studies provide emerging evidence and should be considered alongside practitioner expertise.