Gu Ben Ke Chuan Pian

Root-Strengthening Cough and Wheezing Tablet · 固本咳喘片

Also known as: Gu Ben Ke Chuan Jiao Nang (固本咳喘胶囊, capsule form), Gu Ben Ke Chuan Ke Li (固本咳喘颗粒, granule form)

A modern Chinese herbal formula designed to strengthen the body's foundation and manage chronic cough and wheezing. It works by boosting Qi, reinforcing the Spleen, and supporting the Kidneys, making it suited for people with long-standing respiratory weakness who experience coughing with copious phlegm and shortness of breath that worsens with exertion. This formula is used during remission periods of chronic bronchitis, not during acute flare-ups.

Origin Modern Chinese patent medicine (中成药), included in the Chinese Pharmacopoeia (中国药典). Not derived from a single classical source text but based on classical principles of tonifying the Spleen and supplementing the Kidneys to treat chronic cough and wheezing. — Modern (contemporary Chinese patent medicine)
Composition 7 herbs
Dang Shen
King
Dang Shen
Bu Gu Zhi
King
Bu Gu Zhi
Bai Zhu
Deputy
Bai Zhu
Mai Dong
Deputy
Mai Dong
Fu Ling
Assistant
Fu Ling
Wu Wei Zi
Assistant
Wu Wei Zi
Gan Cao
Envoy
Gan Cao
Explore composition

Educational content Consult qualified TCM practitioners for diagnosis and treatment

Patterns Addressed

In TCM, symptoms don't appear randomly — they cluster into recognizable patterns of disharmony that reveal what's out of balance in the body. Gu Ben Ke Chuan Pian is designed to correct these specific patterns.

Why Gu Ben Ke Chuan Pian addresses this pattern

When Spleen Qi is weak, the Spleen fails in its role of transforming and transporting fluids. Fluids accumulate and congeal into phlegm, which lodges in the Lungs and obstructs breathing. This formula directly addresses Spleen Qi deficiency through its Si Jun Zi Tang core: Dang Shen, Bai Zhu, Fu Ling, and Zhi Gan Cao work together to restore the Spleen's transformative capacity. As Spleen function recovers, phlegm production decreases at its source, and the Lungs gradually clear. The formula's emphasis on strengthening the Spleen reflects the classical teaching that 'the Spleen is the source of phlegm production, and the Lungs are the vessel that stores it.'

A practitioner would look for one or more of these signs

Cough With Copious Clear Sputum

Copious thin white phlegm, especially in the morning

Shortness Of Breath

Worsens with physical activity

Eye Fatigue

General tiredness and lack of stamina

Poor Appetite

Reduced appetite with loose stools

Commonly Prescribed For

These conditions can arise from the patterns above. A practitioner would consider Gu Ben Ke Chuan Pian when these conditions are specifically caused by those patterns — not for all cases of these conditions.

TCM Interpretation

In TCM, chronic bronchitis is understood primarily through the lens of the Lung, Spleen, and Kidney organ systems. In the early stages, repeated external pathogen invasions damage the Lungs. Over time, this weakens Lung Qi, which in turn affects the Spleen (because the Lungs and Spleen share a close mother-child relationship in Five Phase theory). A weakened Spleen fails to properly transform fluids, leading to internal Dampness that congeals into phlegm. This phlegm lodges in the Lungs, perpetuating the cough. In advanced or long-standing cases, the Kidneys also become involved, losing their ability to 'receive' Qi from above. The result is a vicious cycle: Spleen weakness generates phlegm, Lung weakness allows it to accumulate, and Kidney weakness adds breathlessness and wheezing on top.

Why Gu Ben Ke Chuan Pian Helps

Gu Ben Ke Chuan Pian breaks the cycle of chronic bronchitis at multiple points. Its Si Jun Zi Tang core (Dang Shen, Bai Zhu, Fu Ling, Zhi Gan Cao) restores Spleen function to cut off phlegm production at its source. Bu Gu Zhi warms the Kidneys and helps them anchor Qi, addressing the component of breathlessness that comes from Kidney weakness. Mai Dong moistens the Lungs to protect the airway tissue from further damage, while Wu Wei Zi astringes Lung Qi to reduce the cough reflex itself. Because this formula focuses entirely on strengthening the body's own resources rather than attacking pathogens, it is specifically designed for use between acute episodes, helping to extend remission periods and reduce the frequency of flare-ups.

Also commonly used for

Bronchial Asthma

Remission phase in patients with underlying Qi deficiency

Emphysema

With chronic cough, wheezing, and fatigue due to deficiency

Chronic Coughing

Persistent cough due to Spleen-Kidney weakness rather than pathogen invasion

Wheezing

Chronic wheezing worsening with exertion

What This Formula Does

Every TCM formula has a specific set of actions — here's what Gu Ben Ke Chuan Pian does in the body, explained in both everyday and TCM terms

Therapeutic focus

In practical terms, Gu Ben Ke Chuan Pian is primarily used to support these areas of health:

TCM Actions

In TCM terminology, these are the specific therapeutic actions that Gu Ben Ke Chuan Pian performs to restore balance in the body:

How It Addresses the Root Cause

TCM doesn't just suppress symptoms — it aims to resolve the underlying imbalance. Here's how Gu Ben Ke Chuan Pian works at the root level.

Gu Ben Ke Chuan Pian addresses a pattern of chronic cough and wheezing rooted in combined Spleen and Kidney deficiency. In TCM theory, the Spleen is responsible for transforming and transporting fluids. When the Spleen is weak, fluids accumulate and congeal into Phlegm, which rises to obstruct the Lungs. This is why the condition presents with copious sputum and a persistent cough. Meanwhile, the Lungs depend on the Kidneys to "grasp" or anchor the Qi that is inhaled. When Kidney Qi is insecure (肾气不固), the Kidneys fail in this anchoring role, leading to shallow breathing, wheezing, and shortness of breath that gets noticeably worse with physical exertion.

Over time, this deficiency creates a vicious cycle: a weak Spleen generates more Phlegm, which further burdens the Lungs; weakened Kidney Qi means the body cannot maintain deep, stable breathing. The body's defensive Qi (Wei Qi) at the surface also becomes compromised because it depends on the Spleen and Lungs for its production and distribution. This is why patients are often susceptible to repeated respiratory infections, which in turn further deplete the Spleen and Kidneys. The formula intervenes by tonifying Qi and strengthening both the Spleen and Kidneys simultaneously, addressing the root cause rather than merely suppressing symptoms. It is specifically designed for the remission phase of chronic bronchitis, aiming to build up the body's foundational strength so that acute flare-ups become less frequent and less severe.

Formula Properties

Every formula has an inherent temperature, taste, and affinity for specific organs — these properties determine how it interacts with the body

Overall Temperature

Slightly Warm

Taste Profile

Predominantly sweet with mild sour and slightly bitter notes. The sweetness tonifies Qi and the Spleen, the sourness astringes Lung Qi and prevents leakage, and the mild bitterness helps dry Dampness.

Channels Entered

Lung Spleen Kidney

Ingredients

7 herbs

The herbs that make up Gu Ben Ke Chuan Pian, organized by their role in the prescription

King — Main ingredient driving the formula
Deputy — Assists and enhances the King
Assistant — Supports or moderates other herbs
Envoy — Directs the formula to its target
Kings — Main ingredient driving the formula
Dang Shen

Dang Shen

Codonopsis roots

Dosage 151g (per 1000-tablet batch)
Temperature Neutral
Taste Sweet
Organ Affinity Lungs, Spleen

Role in Gu Ben Ke Chuan Pian

The primary Qi-tonifying herb in this formula. Dang Shen strengthens the Spleen and augments Qi, addressing the root deficiency that allows phlegm to accumulate and the Lungs to lose their ability to regulate breathing. Its gentle, nourishing nature makes it ideal for long-term use in chronic conditions.
Bu Gu Zhi

Bu Gu Zhi

Psoralea fruits

Dosage 151g (per 1000-tablet batch)
Temperature Warm
Taste Bitter, Pungent
Organ Affinity Spleen, Kidneys
Preparation Salt-processed (盐炒)

Role in Gu Ben Ke Chuan Pian

Warms the Kidneys and helps them 'grasp' Qi, a function called 'na qi' that prevents inhaled Qi from floating upward and causing wheezing. Salt processing directs its action toward the Kidneys. Bu Gu Zhi is the key herb that addresses the Kidney deficiency component of this pattern, helping the Kidneys anchor breathing and stop chronic wheezing that worsens with physical activity.
Deputies — Assists and enhances the King
Bai Zhu

Bai Zhu

Atractylodes rhizomes

Dosage 151g (per 1000-tablet batch)
Temperature Warm
Taste Bitter, Sweet
Organ Affinity Spleen, Stomach
Preparation Bran-fried (麸炒)

Role in Gu Ben Ke Chuan Pian

Strengthens the Spleen and dries Dampness, supporting Dang Shen's Qi-tonifying action while also helping to resolve the underlying cause of phlegm production. Bran-frying moderates its drying nature and enhances its Spleen-strengthening properties.
Mai Dong

Mai Dong

Dwarf lilyturf roots

Dosage 151g (per 1000-tablet batch)
Temperature Cool
Taste Bitter, Sweet
Organ Affinity Heart, Lungs, Stomach

Role in Gu Ben Ke Chuan Pian

Nourishes Lung Yin and generates fluids, moistening the respiratory tract to ease coughing. Mai Dong also prevents the warm, drying herbs in the formula (Bu Gu Zhi, Bai Zhu) from consuming Yin fluids, maintaining a balance between tonification and moistening.
Assistants — Supports or moderates other herbs
Fu Ling

Fu Ling

Poria-cocos mushrooms

Dosage 100g (per 1000-tablet batch)
Temperature Neutral
Taste Sweet
Organ Affinity Heart, Kidneys, Lungs, Spleen

Role in Gu Ben Ke Chuan Pian

Strengthens the Spleen and promotes water metabolism, helping to transform and eliminate the pathological Dampness that becomes phlegm. Works alongside Bai Zhu to address the Spleen's role in phlegm production, following the classical principle that 'the Spleen is the source of phlegm production.'
Wu Wei Zi

Wu Wei Zi

Schisandra berries

Dosage 75g (per 1000-tablet batch)
Temperature Warm
Taste Sour, Sweet
Organ Affinity Heart, Kidneys, Lungs
Preparation Vinegar-processed (醋制)

Role in Gu Ben Ke Chuan Pian

Astringes the Lungs and stops coughing, while also tonifying the Kidneys to help them receive Qi. Its sour, astringent nature helps contain the leaking of Lung Qi that manifests as chronic cough and shortness of breath. Vinegar processing enhances its astringent and Liver-entering properties.
Envoy — Directs the formula to its target
Gan Cao

Gan Cao

Liquorice

Dosage 75g (per 1000-tablet batch)
Temperature Neutral
Taste Sweet
Organ Affinity Heart, Lungs, Spleen, Stomach

Role in Gu Ben Ke Chuan Pian

Honey-prepared Gan Cao tonifies the Middle Burner, augments Qi, and harmonizes all the other herbs in the formula. It supports the Spleen-strengthening function while moderating the formula's overall action.

Why This Combination Works

How the herbs in Gu Ben Ke Chuan Pian complement each other

Overall strategy

Gu Ben Ke Chuan Pian addresses chronic cough and wheezing caused by deficiency of both the Spleen and Kidneys. The strategy is to 'strengthen the root' (gu ben) by simultaneously tonifying Spleen Qi (to cut off phlegm at its source), warming the Kidneys (to restore their Qi-grasping function), and gently astringing the Lungs (to stop chronic leakage of Lung Qi). Because this is a formula for the remission phase, the emphasis is entirely on strengthening the body rather than expelling pathogens.

King herbs

Dang Shen and Bu Gu Zhi jointly serve as the Kings, each addressing one half of the core pathomechanism. Dang Shen powerfully tonifies Spleen Qi, the foundation of the body's ability to transform fluids and prevent phlegm accumulation. Bu Gu Zhi (salt-processed) warms Kidney Yang and helps the Kidneys 'grasp' inhaled Qi, directly addressing the Kidney deficiency that allows Qi to float upward as wheezing. Together they treat the Spleen-Kidney axis that underlies chronic respiratory weakness.

Deputy herbs

Bai Zhu (bran-fried) reinforces Dang Shen's Spleen-tonifying action while adding a crucial Dampness-drying effect, helping to resolve the fluid stagnation that generates phlegm. Mai Dong provides an essential counterbalance by nourishing Lung Yin and moistening the airways, preventing the warming and drying herbs from damaging the delicate Lung tissue over long-term use.

Assistant herbs

Fu Ling (reinforcing assistant) supports the Spleen-strengthening strategy by promoting healthy water metabolism and draining pathological Dampness, working with Bai Zhu to address phlegm at its root. Wu Wei Zi (restraining assistant) astringes the Lungs to contain chronic Qi leakage, while its Kidney-tonifying sour nature supports Bu Gu Zhi's effort to anchor Qi in the lower body.

Envoy herbs

Zhi Gan Cao harmonizes the formula, moderating any potential conflicts between the warming herbs and the moistening Mai Dong. Its sweet, warm nature also supports the Middle Burner, reinforcing the central Qi-generating axis.

Notable synergies

The Dang Shen-Bai Zhu-Fu Ling combination forms a Si Jun Zi Tang base (minus only raw Gan Cao, replaced here by Zhi Gan Cao), providing a well-established Qi-tonifying foundation. The Bu Gu Zhi and Wu Wei Zi pairing creates a powerful Kidney-anchoring and Lung-astringing synergy, one warming to help the Kidneys grasp Qi and the other sour to contain Lung Qi leakage. Mai Dong's moistening action balances the drying tendency of Bai Zhu and Fu Ling, ensuring the formula can be used long-term without injuring Yin.

How to Prepare

Traditional preparation instructions for Gu Ben Ke Chuan Pian

Gu Ben Ke Chuan Pian is manufactured as a patent medicine tablet. According to the Chinese Pharmacopoeia, the seven herbs are combined in their specified proportions. A portion of Fu Ling (34.5g from 100g total) is ground into a fine powder and set aside. The remaining Fu Ling and the other six herbs are decocted in water three times: the first decoction for 3 hours, the second for 2 hours, and the third for 1 hour. The decoction liquids are filtered, combined, and left to settle for 24 hours. The clear supernatant is filtered again, then concentrated under reduced pressure. Once cooled, the Fu Ling fine powder and appropriate amounts of dextrin are mixed in, dried at low temperature, ground into powder, combined with starch and malt sugar to form granules, and compressed into 1000 film-coated tablets.

The standard dosage is 3 tablets taken orally, 3 times daily. This formula is intended for use during the remission phase of chronic bronchitis and should not be taken during acute flare-ups or when fever exceeds 38.5°C.

Common Modifications

How practitioners adapt Gu Ben Ke Chuan Pian for specific situations

Added
Huang Qi

15-30g, to reinforce defensive Qi and secure the exterior

Fang Feng

6-9g, to expel residual Wind from the surface

Adding Huang Qi and Fang Feng creates a Yu Ping Feng San-like combination within the formula, strengthening the body's surface defense against recurrent respiratory infections triggered by cold and wind exposure.

Educational content — always consult a qualified healthcare provider or TCM practitioner before using any herbal formula.

Contraindications

Situations where Gu Ben Ke Chuan Pian should not be used or requires extra caution

Avoid

Active cold or flu with fever. This formula is a tonic meant for the remission phase of chronic bronchitis and should not be used during acute infections or when external pathogens are present.

Avoid

Known allergy to any of the formula's ingredients. Those with allergic constitutions should use with extra caution.

Avoid

Acute exacerbation of chronic bronchitis, bronchiectasis, lung abscess, cor pulmonale, or pulmonary tuberculosis. These conditions require medical evaluation rather than OTC tonification.

Avoid

Fever above 38.5°C, sudden worsening of wheezing or breathlessness, or significant increase in sputum volume during treatment. The formula should be stopped and medical attention sought.

Caution

Patients with severe hypertension, heart disease, liver disease, diabetes, or kidney disease should only use this formula under medical supervision.

Caution

Cough or wheezing caused by Excess Heat, Phlegm-Heat, or Yin deficiency with Empty Fire. This formula is warming and tonifying, designed for deficiency-cold patterns, and may worsen Heat-type presentations.

Caution

If symptoms do not improve after 4 weeks of use, the formula should be discontinued and medical evaluation sought.

Special Populations

Important considerations for pregnancy, breastfeeding, and pediatric use

Pregnancy

The official product labeling states that pregnant women should only use this formula under medical supervision. Bu Gu Zhi (Psoralea fruit), present in the full formulation, has warming and Kidney-tonifying properties, and while it is not classified as a pregnancy-prohibited herb, its effects on pregnancy have not been formally studied. Dang Shen, Bai Zhu, Fu Ling, and Zhi Gan Cao are generally considered safe in pregnancy, but the formula as a whole has not undergone specific pregnancy safety testing. Pregnant women should consult a qualified practitioner before use.

Breastfeeding

The official product labeling advises that breastfeeding women should use this formula only under medical guidance. The herbs in this formula are generally mild tonics, and no specific toxicity concerns through breast milk have been documented. However, Zhi Gan Cao (honey-processed Licorice) in sustained doses could theoretically affect electrolyte balance, and Bu Gu Zhi contains psoralen compounds whose transfer into breast milk has not been studied. Breastfeeding mothers should consult a practitioner before use.

Children

The official product labeling states that children must use this formula under adult supervision. No specific pediatric dosage is provided in the standard product information, so dosage should be determined by a qualified practitioner based on the child's age and weight. Generally, children under 3 years should not use this product without explicit medical guidance. For older children, half the adult dose is a common starting point, but individual assessment is essential. The formula is tonifying in nature and relatively gentle, but children's constitutions tend to run warmer, so signs of Heat should be monitored during use.

Drug Interactions

If you are taking pharmaceutical medications, be aware of these potential interactions with Gu Ben Ke Chuan Pian

Gan Cao (Licorice root): Zhi Gan Cao in this formula contains glycyrrhizin, which can cause potassium depletion and sodium retention with prolonged use. This may interact with diuretics (increasing risk of hypokalemia), cardiac glycosides like digoxin (hypokalemia increases digoxin toxicity), corticosteroids (additive potassium-lowering effect), and antihypertensive medications (sodium retention may counteract blood pressure control).

Bu Gu Zhi (Psoralea fruit): Contains psoralen and isopsoralen, which are photosensitizing compounds. Concurrent use with other photosensitizing drugs (e.g., tetracyclines, fluoroquinolones, certain diuretics) may increase the risk of photosensitivity reactions. Bu Gu Zhi has also been associated with rare cases of hepatotoxicity, so caution is warranted when combining with other hepatotoxic medications or in patients with pre-existing liver conditions.

The official labeling notes that if other medications are being used concurrently, a physician or pharmacist should be consulted before taking this formula.

Usage Guidance

Practical advice for getting the most out of Gu Ben Ke Chuan Pian

Best time to take

Three times daily after meals, to reduce any potential gastrointestinal discomfort from the tonifying herbs.

Typical duration

Typically taken for 2-4 weeks during the remission phase of chronic bronchitis, reassessed if no improvement after 4 weeks.

Dietary advice

Avoid foods that are difficult to digest, including greasy, fatty, or heavily processed foods, as these burden the already-weakened Spleen and promote further Phlegm production. Avoid cold and raw foods (ice cream, cold salads, chilled drinks) which can impair Spleen Yang and worsen Phlegm accumulation. Reduce intake of excessively sweet or sugary foods, which generate Dampness. Favor warm, easily digestible meals such as congee, cooked vegetables, soups with ginger, and lightly seasoned lean proteins. Include modest amounts of foods that support Lung and Spleen health, such as white radish, pear (cooked), lotus seed, and Chinese yam (Shan Yao).

Gu Ben Ke Chuan Pian originates from Modern Chinese patent medicine (中成药), included in the Chinese Pharmacopoeia (中国药典). Not derived from a single classical source text but based on classical principles of tonifying the Spleen and supplementing the Kidneys to treat chronic cough and wheezing. Modern (contemporary Chinese patent medicine)

Classical Texts

Key passages from the classical Chinese medical texts that first described Gu Ben Ke Chuan Pian and its clinical use

Gu Ben Ke Chuan Pian is a modern Chinese patent medicine (中成药) rather than a formula from a classical text, so there are no direct classical quotations attributing this specific formula to an ancient source. However, the formula draws heavily on classical principles:

The concept of treating chronic cough and wheezing by strengthening the Spleen and Kidneys reflects the classical teaching that "the Spleen is the source of Phlegm production, and the Lungs are the vessel that stores it" (脾为生痰之源,肺为贮痰之器). This well-known aphorism, found across multiple traditional sources, underpins the formula's strategy of addressing Phlegm at its root by tonifying the Spleen.

The principle of tonifying the Kidneys to grasp Qi (纳气归肾) for chronic wheezing conditions also reflects long-standing TCM theory. The formula's inclusion of Bu Gu Zhi specifically addresses the classical understanding that the Kidneys are responsible for "receiving" or "grasping" the Qi breathed in by the Lungs, so that when Kidney Qi is insecure, breath becomes shallow and wheezing worsens with physical activity.

Historical Context

How Gu Ben Ke Chuan Pian evolved over the centuries — its origins, lineage, and place in the broader tradition of Chinese medicine

Gu Ben Ke Chuan Pian is a modern Chinese patent medicine developed in the People's Republic of China for the management of chronic bronchitis during its remission phase. It is not derived from a single classical formula but rather synthesizes several well-established TCM treatment principles into a convenient tablet form. Its core strategy of tonifying the Spleen to address Phlegm production draws on the classical Si Jun Zi Tang (Four Gentlemen Decoction) framework, which has been the foundational Qi-tonifying formula since the Song Dynasty. The addition of Mai Dong and Wu Wei Zi echoes the Sheng Mai San (Generate the Pulse Powder) concept of supplementing Qi while preserving Yin and astringing the Lungs.

The inclusion of Bu Gu Zhi (Psoralea fruit) to warm the Kidneys and help them "grasp" Qi reflects a treatment approach that became increasingly refined during the Ming and Qing Dynasties, when physicians like Zhang Jingyue (张景岳) emphasized the Kidney's role in chronic respiratory disease. Pharmacological research conducted by the manufacturer Jinghua Pharmaceutical has shown that the formula can enhance immune function and exert anti-inflammatory effects, supporting its traditional use in reducing the frequency and severity of chronic bronchitis exacerbations.