Formula

Xin Yi San

Magnolia Flower Formula | 辛夷散

Also known as:

Magnolia Flower Powder

Properties

Exterior-releasing formulas · Warm

Key Ingredients

Xin Yi Hua

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Select Product Type

Select Supplier

Select Size

Quantity

$44.00 ($0.44/g)
Made to order · Non-cancellable once ordered · Policy
For shipments to: United States Change
Standard Shipping (3-5 business days): $4.99
Express Shipping (1-2 business days): $9.99
Free shipping on orders over $75

About This Formula

Traditional Chinese Medicine background and properties

Formula Description

A classical formula for nasal congestion, runny nose, loss of smell, and sinus headaches caused by Wind-Cold blocking the nasal passages. It uses aromatic, upward-moving herbs to open the nose and restore normal breathing. Originally designed as a fine powder taken with green tea, it is one of the most widely used traditional formulas for chronic and acute nasal conditions.

Formula Category

Main Actions

  • Disperses Wind-Cold
  • Unblocks the Nasal Passages
  • Drains Dampness
  • Raises Clear Yang
  • Alleviates Pain

TCM Patterns

In TCM, symptoms don't appear randomly — they cluster into recognizable patterns of disharmony that reveal what's out of balance in the body. Xin Yi San is traditionally associated with these specific patterns.

The following describes this formula's classification within Traditional Chinese Medicine theory and is provided for educational purposes only.

Why Xin Yi San addresses this pattern

When Wind-Cold invades the Lung system, it can lodge in the nasal passages, which are the 'opening' of the Lungs. The pathogenic factor obstructs the free flow of Lung Qi through the nose, causing congestion, copious clear or white nasal discharge, loss of smell, and headache. The tongue coating is typically thin and white, and the pulse is floating. Xin Yi San directly targets this mechanism: Xin Yi Hua, Xi Xin, Bai Zhi, Fang Feng, and Qiang Huo disperse Wind-Cold from the exterior and head region, while Sheng Ma and Gao Ben raise clear Yang to restore Lung Qi's normal descending and dispersing function through the nasal passages. The formula is especially appropriate when the Wind-Cold has settled specifically in the nose rather than causing generalized body aches and fever.

A practitioner would look for one or more of these signs

Nasal Congestion

Persistent nasal stuffiness, often alternating sides or bilateral

Runny Nose

Copious clear or white watery nasal discharge

Loss Of Smell

Inability to smell or diminished sense of smell

Headaches

Frontal or vertex headache accompanying nasal congestion

Sneezing

Frequent sneezing triggered by Wind exposure or temperature changes

How It Addresses the Root Cause

In Chinese medicine, the nose is the sensory opening of the Lungs. When the Lungs are functioning well, the nasal passages remain clear, breathing is unobstructed, and the sense of smell is sharp. However, when the Lung's defensive Qi is weak or insufficient, external pathogenic factors (especially Wind-Cold and Dampness) can invade and lodge in the nasal passages.

When Wind-Cold blocks the nasal orifices, the Lung's ability to disperse and descend its Qi is impaired. Clear Yang, the light, ascending force that should nourish the head and sensory organs, fails to rise properly. Meanwhile, turbid Yin (heavy, cloudy substances) accumulates and cannot descend. This blockage produces the hallmark symptoms: stuffed nose, copious clear or white nasal discharge, inability to smell, and a heavy sensation in the head. In chronic or severe cases, the stagnation of Qi and fluids can congeal into nasal polyps, which classical commentators compared to "mushrooms growing on damp ground exposed to warmth."

Xin Yi San addresses this by powerfully dispersing the Wind-Cold lodged in the nasal passages while simultaneously restoring the proper ascending of clear Yang to the head. The formula also incorporates a descending component (Mu Tong and green tea as the vehicle) to drain turbidity downward through urination, creating a balanced dynamic of "ascending the clear and descending the turbid" that restores normal Lung function and reopens the nasal orifices.

Formula Properties

Temperature

Warm

Taste Profile

Predominantly acrid (pungent) with a sweet undertone. The acrid taste disperses Wind-Cold and opens the orifices; the mild sweetness from Gan Cao harmonizes and moderates the formula's strong dispersing action.

Target Organs
Lungs Stomach
Channels Entered
Lung Stomach Bladder

Formula Origin

Yan Shi Ji Sheng Fang (严氏济生方, Yan's Formulas to Aid the Living) by Yan Yonghe

This is just partial information on the formula's TCM properties. More detailed information is available on the formula's dedicated page

Ingredients in Xin Yi San

Detailed information about each herb in Xin Yi San and their roles

Kings
Deputies
Assistants
Envoys
Xin Yi Hua
Xin Yi Hua

Magnolia flower bud

Dosage: 3 - 9g

Temperature Warm
Taste Acrid / Pungent (辛 xīn)
Organ Affinity Lungs, Stomach
Parts Used Flower bud (花蕾 huā lěi)
Role in Xin Yi San

The chief herb and namesake of the formula. Warm and acrid, it enters the Lung and Stomach channels and is the premier herb in the Chinese materia medica for unblocking the nasal passages. It disperses Wind-Cold from the head and face, opens the nose, and relieves nasal congestion and headache.

Xi Xin
Xi Xin

Wild Ginger

Dosage: 1 - 3g

Temperature Warm
Taste Acrid / Pungent (辛 xīn)
Organ Affinity Heart, Lungs, Kidneys
Parts Used Root (根 gēn)
Role in Xin Yi San

Strongly acrid and warming, Xi Xin disperses Wind-Cold and penetrates all nine orifices. It powerfully opens the nasal passages and is classically described as able to 'break through congestion and move Qi through the orifices.' It enhances the King herb's ability to unblock the nose.

Bai Zhi
Bai Zhi

Dahurian angelica root

Dosage: 3 - 6g

Temperature Warm
Taste Acrid / Pungent (辛 xīn)
Organ Affinity Lungs, Stomach, Large Intestine
Parts Used Root (根 gēn)
Role in Xin Yi San

Acrid and warm, Bai Zhi enters the Lung and Stomach channels. It relieves the exterior, disperses Wind from the Yangming channel, opens the nasal passages, expels Dampness, and alleviates frontal headache and sinus pain. Together with Xin Yi Hua and Sheng Ma, it raises clear Qi upward to the head.

Sheng Ma
Sheng Ma

Cimicifuga rhizome

Dosage: 3 - 6g

Temperature Slightly Cool
Taste Acrid / Pungent (辛 xīn), Sweet (甘 gān)
Organ Affinity Lungs, Spleen, Stomach, Large Intestine
Parts Used Rhizome (根茎 gēn jīng)
Role in Xin Yi San

Ascending in nature, Sheng Ma lifts the clear Yang of the Stomach upward toward the head, directing the other herbs to the nasal region. It also clears Heat and releases toxins from the skin and muscle layer, helping to resolve congestion in the upper body.

Gao Ben
Gao Ben

Chinese Ligusticum rhizome

Dosage: 3 - 6g

Temperature Warm
Taste Acrid / Pungent (辛 xīn)
Organ Affinity Urinary Bladder
Parts Used Rhizome (根茎 gēn jīng)
Role in Xin Yi San

Acrid and warm, Gao Ben enters the Bladder channel and ascends to the vertex of the head. It disperses Wind-Cold-Dampness from the upper body, overcomes Dampness, and relieves vertex headache. It reinforces the overall ascending, opening strategy of the formula.

Fang Feng
Fang Feng

Siler root

Dosage: 3 - 6g

Temperature Slightly Warm
Taste Acrid / Pungent (辛 xīn), Sweet (甘 gān)
Organ Affinity Urinary Bladder, Liver, Spleen
Parts Used Root (根 gēn)
Role in Xin Yi San

A gentle Wind-dispersing herb that releases the exterior and overcomes Dampness. Fang Feng works broadly across multiple channels to expel Wind and is often called the 'master of Wind treatment.' It reinforces the exterior-releasing action of the formula while being milder than Xi Xin.

Qiang Huo
Qiang Huo

Notopterygium root and rhizome

Dosage: 3 - 6g

Temperature Warm
Taste Acrid / Pungent (辛 xīn), Bitter (苦 kǔ)
Organ Affinity Urinary Bladder, Kidneys
Parts Used Rhizome (根茎 gēn jīng)
Role in Xin Yi San

Acrid, bitter, and warm, Qiang Huo releases the exterior, disperses Cold and Dampness, and directs Qi along the Taiyang (Greater Yang) channel and the Governing Vessel toward the upper back and head. It reinforces the overall Wind-Cold dispersing and Dampness-overcoming action of the formula.

Chuan Xiong
Chuan Xiong

Sichuan lovage rhizome

Dosage: 3 - 6g

Temperature Warm
Taste Acrid / Pungent (辛 xīn)
Organ Affinity Liver, Gallbladder, Pericardium
Parts Used Rhizome (根茎 gēn jīng)
Role in Xin Yi San

Known as the 'herb that reaches the top of the head,' Chuan Xiong moves Blood, dispels Blood stasis, and relieves pain, especially headache. It invigorates circulation in the head, helping to break through congestion that Wind-Cold stasis causes. It is classically noted as a guiding herb (使药) for Xin Yi.

Mu Tong
Mu Tong

Akebia stem

Dosage: 3 - 6g

Temperature Cold
Taste Bitter (苦 kǔ)
Organ Affinity Heart, Small Intestine, Urinary Bladder
Parts Used Stem (茎 jīng)
Role in Xin Yi San

Bitter and cold, Mu Tong promotes urination and drains Dampness downward. In this predominantly ascending formula, it provides a crucial counterbalance by directing turbid Dampness and Heat downward through the urinary tract. This 'lowering' action prevents the many warm, upward-moving herbs from being too one-directional.

Gan Cao
Gan Cao

Licorice root

Dosage: 3 - 6g

Temperature Neutral
Taste Sweet (甘 gān)
Organ Affinity Heart, Lungs, Spleen, Stomach
Parts Used Root (根 gēn)
Role in Xin Yi San

Harmonizes all the other herbs in the formula and moderates their acrid, dispersing nature so they do not overly scatter the body's Qi. Its sweet, neutral quality also gently supports the Spleen and Stomach, protecting the middle from the many pungent, drying herbs.

Modern Research (3 studies)

  • Randomized double-blind clinical trial of Xin-yi-san for perennial allergic rhinitis (2010)
  • CYP1A2 inhibition by Xin-yi-san and interaction with theophylline: human and in vitro study (2024)
See all research on the formula page

Usage & Safety

How to use this formula and important safety information

Important Medical Disclaimer

The information provided here is for educational purposes only and is not intended as medical advice or to replace consultation with a qualified healthcare professional. This formula is a dietary supplement and has not been evaluated by the FDA. It is not intended to diagnose, treat, cure, or prevent any disease.

Always consult with a qualified healthcare provider, particularly if you are pregnant, nursing, have a medical condition, or are taking other medications. Discontinue use and consult your healthcare provider if you experience any adverse reactions.

Recommended Dosage

Instructions for safe storage and consumption

Loading storage and consumption information...

Best Time to Take

After meals (食后), traditionally mixed with clear green tea, taken 2-3 times daily.

Typical Duration

Acute use: 3-7 days for common cold with nasal congestion. For chronic rhinitis or sinusitis, may be used for 2-4 weeks with periodic reassessment, but should not be taken long-term without modification due to the drying nature of the acrid herbs.

Dietary Advice

While taking this formula, avoid cold and raw foods (such as iced drinks, raw salads, ice cream, and chilled fruit) as these can worsen the Cold obstruction in the nasal passages and counteract the warming, dispersing effect of the herbs. Avoid greasy, oily, or heavy foods that generate Dampness and Phlegm, which can worsen nasal congestion. Favor warm, lightly cooked foods and warm beverages. Ginger tea, congee with scallions, and light soups are supportive. Avoid excessive dairy products, which are considered Phlegm-producing in TCM and may worsen nasal discharge. The original formula is traditionally taken with clear green tea (茶清), so pairing with a light green tea is appropriate and historically consistent.

Modern Usage

This classical formula, made from nine herbal ingredients, is used to expel Wind and clear the nasal passages. It is mainly utilized to disperse Wind, dispel cold, eliminate Dampness, and relieve sinus obstruction.

This formula is often used to alleviate symptoms such as sinus congestion, sinus headaches, nasal discharge, and discomforts associated with seasonal allergies or the common cold.

Special Populations

Pregnancy

Contraindicated during pregnancy. Xin Yi (Magnolia flower bud) has been traditionally recognized as capable of stimulating uterine contractions. The formula also contains Xi Xin (Asarum) and multiple strongly acrid, dispersing herbs (Chuan Xiong, Qiang Huo, Fang Feng) that move Qi and Blood vigorously, which could pose risks to the developing fetus. Classical sources specify that Xin Yi's uterine-stimulating properties are only appropriate during active labor. Women who are pregnant or planning to become pregnant should not use this formula.

Breastfeeding

No specific classical prohibitions exist for breastfeeding mothers. However, the formula contains Xi Xin (Asarum), which has potent volatile compounds, and Mu Tong (Akebia), which may transfer bioactive substances through breast milk. The strongly acrid and dispersing nature of the formula could theoretically affect milk quality or quantity in some individuals. If breastfeeding mothers need to use this formula, it should be under professional guidance and for the shortest duration necessary. Monitor the infant for any signs of restlessness, loose stools, or feeding changes.

Pediatric Use

Classical sources include pediatric adaptations of Xin Yi San with reduced dosage. The Ming Dynasty text Qi Xiao Liang Fang specifies "one qian per serving" for children (half the adult dose). The classical principle states that children's organs are 'delicate and immature' and cannot tolerate heavy medication. Modern pediatric use should follow similar reductions: generally one-third to one-half the adult dose depending on the child's age and weight. Xin Yi (Magnolia flower) has fine hairs that can irritate the throat, so it must be wrapped in cloth when decocting (bao jian). Xi Xin (Asarum) should be used cautiously in children at minimal doses. Not recommended for infants under age 3 due to the potency of the volatile aromatic herbs. For children over 3, use under professional supervision with close monitoring. Stop use if the child develops dizziness, dry mouth, or irritability.

Drug Interactions

Theophylline and aminophylline: This is the most well-documented interaction. Bai Zhi (Angelica dahurica) in this formula contains furanocoumarins, particularly imperatorin, which are potent inhibitors of CYP1A2, the primary enzyme responsible for theophylline metabolism. Research has shown that concurrent use of Xin Yi San can decrease theophylline clearance by 27-33%, prolong its half-life, and increase adverse effects including headaches and tachycardia. Patients taking theophylline should avoid this formula or have their theophylline dose adjusted under medical supervision.

Other CYP1A2 substrates: Given the demonstrated CYP1A2 inhibitory activity, caution is warranted with other medications primarily metabolized by this enzyme, including caffeine, clozapine, olanzapine, duloxetine, melatonin, and fluvoxamine. Plasma levels of these drugs could potentially be elevated.

Gan Cao (Glycyrrhiza/Licorice): The formula contains processed licorice, which with prolonged use may cause pseudoaldosteronism (fluid retention, potassium loss, blood pressure elevation). This is relevant for patients on antihypertensives, diuretics, digoxin, or corticosteroids, where electrolyte imbalances could be clinically significant.

Contraindications

Avoid

Yin deficiency with Empty Fire (symptoms such as chronic dry mouth, night sweats, hot flashes). The formula's many warm, acrid, dispersing herbs will further deplete Yin fluids and worsen Heat signs.

Avoid

Nasal conditions due to Heat patterns presenting with thick yellow nasal discharge, red tongue with yellow coating, and rapid pulse. This formula is designed for Wind-Cold, not Wind-Heat or Damp-Heat.

Avoid

Pregnancy. Xin Yi (Magnolia flower) may stimulate uterine contractions, and the formula contains multiple acrid dispersing herbs that are not appropriate during pregnancy.

Caution

Patients with profuse sweating or significant Qi deficiency. The strong dispersing and ascending nature of the formula may further deplete Qi and body fluids.

Caution

Prolonged use beyond the acute symptomatic phase. Classical texts caution that extended use of Wind-dispersing formulas will deplete vital essence and Yin fluids. As a classical teaching states: 'all Wind-dispelling medicines inevitably dry out essential fluids.'

Caution

Concurrent use with theophylline or other narrow-therapeutic-index drugs metabolized by CYP1A2. Research has shown Xin Yi San contains potent CYP1A2 inhibitors (particularly imperatorin from Bai Zhi) that can increase adverse effects when combined with theophylline.

Cautions & Warnings

Although this formula is typically safe for most individuals, it may cause side effects in some people. Pregnant women, nursing mothers, postpartum women, and those with liver disease should use the formula with caution.

As with any Chinese herbal remedy, it is advisable to seek guidance from a qualified TCM practitioner before beginning treatment.

Product Details

Manufacturing, supplier, and product specifications

Product Type

Granules

Quantity Description

Loading quantity information...

Concentration Ratio

Loading concentration information...

Fabrication Method

Loading fabrication information...

Supplier Certifications

Loading certifications information...

Supplier Information

Treasure of the East

Loading supplier information...

Loading supplier attributes...

Miscellaneous Info

No additional information available