Formula

Pu Ji Xiao Du Yin

Pu Ji Detox Formula | 普济消毒饮

Also known as:

Universal Benefit Drink to Eliminate Toxin Drink , Universal Clearing Decoction

Properties

Heat-clearing formulas · Cold

Key Ingredients

Huang Qin, Huang Lian

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

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$47.00 ($0.47/g)
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About This Formula*

Traditional Chinese Medicine background and properties

Formula Description*

A classical formula designed to clear intense heat and toxins from the head and face, and to relieve sore throat and swelling. It was originally created during an epidemic to treat severe facial swelling, fever, and throat obstruction caused by Wind-Heat toxins attacking the upper body. Today it is widely used for conditions such as mumps, tonsillitis, facial erysipelas, and other acute infections with prominent redness, swelling, and pain of the head and face.

Formula Category*

Main Actions*

  • Clears Heat and Resolves Toxicity
  • Disperses Wind-Heat
  • Disperses Swelling and Dissipates Nodules
  • Benefits the Throat
  • Vents pathogenic factors from the Upper Burner

TCM Patterns*

In TCM, symptoms don't appear randomly — they cluster into recognizable patterns of disharmony that reveal what's out of balance in the body. Pu Ji Xiao Du Yin is traditionally associated with these specific patterns.

The following describes this formula's classification within Traditional Chinese Medicine theory and is provided for educational purposes only.

Why Pu Ji Xiao Du Yin addresses this pattern

This is the primary pattern this formula was designed to treat, originally termed "Da Tou Wen" (大头瘟, Big Head Plague). Wind-Heat epidemic toxins invade the body and become trapped in the Upper Burner between the Heart and Lungs. Because the Shaoyang and Yangming channels both originate in the face, these toxins surge upward along these pathways, causing intense congestion of Qi and Blood in the head and face. This produces the characteristic dramatic redness, swelling, and burning pain of the head and face, along with throat obstruction and inability to open the eyes.

Pu Ji Xiao Du Yin addresses this pattern on multiple levels: the heavy dose of Huang Qin and Huang Lian directly drains the toxic Heat from the Heart-Lung area; Niu Bang Zi, Lian Qiao, Bo He, and Jiang Can disperse the Wind-Heat outward from the surface; Ban Lan Gen, Xuan Shen, and Ma Bo augment the toxin-resolving power and specifically relieve the throat; and Sheng Ma with Chai Hu guide everything upward to the disease site while venting pent-up Fire.

A practitioner would look for one or more of these signs

Facial Swelling

Red, hot, swollen face and head with burning pain

Sore Throat

Throat obstruction with difficulty swallowing

Fever

Fever with initial chills

Ear Swelling

Eyes swollen shut, unable to open

Thirst

Dry mouth and tongue, thirst

Red Tongue

Red tongue with yellow coating

How It Addresses the Root Cause*

Pu Ji Xiao Du Yin targets a condition the classical texts call "Da Tou Wen" (大头瘟, "Big Head Plague"), a pattern where epidemic Wind-Heat toxin invades and becomes trapped in the Upper Burner, specifically lodging between the Heart and Lungs. In TCM terms, this toxic Heat congests in the upper body and rushes upward to the head, face, and throat, causing intense redness, burning swelling, and pain.

The key pathological dynamic is a blockage of Qi and Blood circulation in the head and face caused by the accumulation of Heat-toxin. Because the pathogenic factor has both a Wind component (which tends to attack the upper body and exterior) and a toxic Heat component (which causes inflammation, swelling, and tissue damage), the result is dramatic: the face and head swell with hot, painful redness, the eyes may swell shut, and the throat becomes obstructed and painful. The tongue becomes dry, reflecting how intense Heat scorches body fluids. The pulse is floating (indicating the pathogen is still partly in the exterior) and rapid and forceful (reflecting strong interior Heat).

Crucially, Li Dongyuan emphasized that this Heat sits in the Upper Burner, not the Stomach or intestines. He specifically criticized the use of purgative formulas like Cheng Qi Tang, which drain Heat downward through the bowels. Since the disease is above, purging below fails to reach the pathogen. Instead, the correct strategy is to directly clear the Heat-toxin where it lodges (the Upper Burner), while simultaneously venting the Wind-Heat outward and upward through the body's surface, giving the pathogen a route of escape.

Formula Properties*

Temperature

Cold

Taste Profile

Predominantly bitter and acrid, with a secondary sweet component. Bitter to drain Fire and resolve toxicity, acrid to disperse Wind-Heat and vent the pathogen outward, and sweet to moderate the harshness of the bitter-cold herbs and protect the Stomach.

Target Organs
Lungs Stomach Heart
Channels Entered
Lung Stomach Large Intestine Gallbladder Liver

Formula Origin

Dōng Yuán Shì Xiào Fāng (東垣試效方, Dong-Yuan's Tried and Tested Formulas) by Li Dongyuan (Li Gao)

This is just partial information on the formula's TCM properties. More detailed information is available on the formula's dedicated page

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Product Details

Manufacturing, supplier, and product specifications

Product Type

Granules

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Supplier Information

Treasure of the East

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Ingredients in Pu Ji Xiao Du Yin

Detailed information about each herb in Pu Ji Xiao Du Yin and their roles

Kings
Deputies
Assistants
Envoys
Huang Qin
Huang Qin

Baical skullcap root

Dosage: 10 - 15g

Temperature Cold
Taste Bitter (苦 kǔ)
Organ Affinity Lungs, Gallbladder, Spleen, Large Intestine, Small Intestine, Heart, Stomach
Parts Used Root (根 gēn)
Role in Pu Ji Xiao Du Yin

Wine-processed Huang Qin is bitter and cold, entering the Lung and Heart channels. It powerfully clears Heat and drains Fire from the Upper Burner, directly targeting the toxic Heat congested in the head and face. Its wine processing helps direct its action upward.

Huang Lian
Huang Lian

Coptis rhizome

Dosage: 10 - 15g

Temperature Cold
Taste Bitter (苦 kǔ)
Organ Affinity Heart, Liver, Stomach, Large Intestine, Gallbladder, Spleen
Parts Used Rhizome (根茎 gēn jīng)
Role in Pu Ji Xiao Du Yin

Wine-processed Huang Lian is bitter and cold, with strong Heat-clearing and toxin-resolving capacity. Together with Huang Qin, it forms the core pair that drains intense Fire toxin from the Heart and Lung, addressing the root cause of the head and facial swelling.

Niu Bang Zi
Niu Bang Zi

Burdock fruit

Dosage: 3 - 10g

Temperature Cold
Taste Acrid / Pungent (辛 xīn), Bitter (苦 kǔ)
Organ Affinity Lungs, Stomach
Parts Used Seed (种子 zhǒng zǐ / 子 zǐ / 仁 rén)
Role in Pu Ji Xiao Du Yin

Acrid and cool, Niu Bang Zi disperses Wind-Heat from the head and face, benefits the throat, and helps vent Heat toxins outward through the exterior. It supports the King herbs by clearing both Wind and Heat.

Lian Qiao
Lian Qiao

Forsythia fruit

Dosage: 3 - 10g

Temperature Slightly Cool
Taste Bitter (苦 kǔ)
Organ Affinity Lungs, Heart, Small Intestine
Parts Used Fruit (果 guǒ / 果实 guǒ shí)
Role in Pu Ji Xiao Du Yin

Lian Qiao clears Heat, resolves toxins, and disperses swellings and nodules. It reinforces the Wind-Heat dispersing action and helps reduce the inflammatory swelling of the head and face.

Bo He
Bo He

Peppermint herb

Dosage: 3 - 6g

Temperature Cool
Taste Acrid / Pungent (辛 xīn), Aromatic (芳香 fāng xiāng)
Organ Affinity Lungs, Liver
Parts Used Whole plant / Aerial parts (全草 quán cǎo)
Role in Pu Ji Xiao Du Yin

Acrid and cool, Bo He disperses Wind-Heat, clears the head and eyes, and benefits the throat. Its light, ascending nature helps lift the formula's actions to the head and face where the pathogen is concentrated.

Jiang Can
Jiang Can

Silkworm

Dosage: 2 - 6g

Temperature Neutral
Taste Acrid / Pungent (辛 xīn), Salty (咸 xián)
Organ Affinity Liver, Lungs, Stomach
Parts Used Animal — whole (全虫 quán chóng)
Role in Pu Ji Xiao Du Yin

Jiang Can disperses Wind, resolves phlegm, and dissipates nodules and swelling. It adds a unique capacity to disperse knotted toxic swelling in the head and face that neither pure Heat-clearing nor Wind-dispersing herbs can fully address.

Xuan Shen
Xuan Shen

Figwort root

Dosage: 6 - 10g

Temperature Cold
Taste Sweet (甘 gān), Bitter (苦 kǔ), Salty (咸 xián)
Organ Affinity Lungs, Stomach, Kidneys
Parts Used Root (根 gēn)
Role in Pu Ji Xiao Du Yin

Xuan Shen clears Heat, cools the Blood, nourishes Yin, and resolves toxins. It reinforces the Heat-clearing action while protecting Yin fluids that are easily damaged by intense Fire toxin, and helps relieve throat swelling.

Ban Lan Gen
Ban Lan Gen

Isatis root

Dosage: 3 - 10g

Temperature Cold
Taste Bitter (苦 kǔ)
Organ Affinity Heart, Stomach
Parts Used Root (根 gēn)
Role in Pu Ji Xiao Du Yin

Ban Lan Gen clears Heat, resolves toxins, and cools the Blood. It powerfully augments the formula's anti-toxic action, particularly targeting epidemic toxins and benefiting the throat.

Ma Bo
Ma Bo

Puffball

Dosage: 3 - 6g

Temperature Neutral
Taste Acrid / Pungent (辛 xīn)
Organ Affinity Lungs
Parts Used Fungus / Mushroom (菌类 jūn lèi)
Role in Pu Ji Xiao Du Yin

Ma Bo clears the Lungs, resolves Fire toxin, and specifically benefits the throat by reducing swelling and relieving sore throat. It works alongside Jie Geng and Gan Cao to address throat obstruction.

Jie Geng
Jie Geng

Balloon flower root

Dosage: 3 - 6g

Temperature Neutral
Taste Bitter (苦 kǔ), Acrid / Pungent (辛 xīn)
Organ Affinity Lungs
Parts Used Root (根 gēn)
Role in Pu Ji Xiao Du Yin

Jie Geng opens and diffuses Lung Qi, benefits the throat, and acts as a 'boat' (舟楫) that carries the other herbs upward to the Upper Burner. It prevents the bitter, cold herbs from sinking downward, ensuring they reach the disease site in the head and throat.

Gan Cao
Gan Cao

Licorice root

Dosage: 3 - 6g

Temperature Neutral
Taste Sweet (甘 gān)
Organ Affinity Heart, Lungs, Spleen, Stomach
Parts Used Root (根 gēn)
Role in Pu Ji Xiao Du Yin

Raw Gan Cao clears Heat, resolves toxins, benefits the throat, and harmonizes the actions of all the other herbs. It also mildly tonifies Qi to support the body's resistance against the pathogen.

Chen Pi
Chen Pi

Tangerine peel

Dosage: 3 - 6g

Temperature Warm
Taste Acrid / Pungent (辛 xīn), Bitter (苦 kǔ)
Organ Affinity Lungs, Spleen
Parts Used Peel / Rind (皮 pí / 果皮 guǒ pí)
Role in Pu Ji Xiao Du Yin

Chen Pi regulates Qi and resolves congestion, preventing the large dose of bitter, cold herbs from causing Qi stagnation and protecting the Stomach. It helps disperse the local Qi congestion that accompanies the toxic swelling.

Chai Hu
Chai Hu

Bupleurum root

Dosage: 3 - 6g

Temperature Slightly Cool
Taste Acrid / Pungent (辛 xīn), Bitter (苦 kǔ)
Organ Affinity Liver, Gallbladder, Lungs
Parts Used Root (根 gēn)
Role in Pu Ji Xiao Du Yin

Chai Hu disperses Wind-Heat along the Shaoyang channel (which traverses the sides of the head and ear region) and guides the formula's actions upward to the head and face. It also embodies the principle of 'venting pent-up Fire' (火郁发之), helping release constrained Heat rather than simply suppressing it.

Sheng Ma
Sheng Ma

Cimicifuga rhizome

Dosage: 2 - 6g

Temperature Slightly Cool
Taste Acrid / Pungent (辛 xīn), Sweet (甘 gān)
Organ Affinity Lungs, Spleen, Stomach, Large Intestine
Parts Used Rhizome (根茎 gēn jīng)
Role in Pu Ji Xiao Du Yin

Sheng Ma clears Heat, resolves toxins, and lifts the actions of other herbs upward along the Yangming channel to the face and head. Together with Chai Hu, it ensures the formula reaches the disease site in the upper body and helps vent constrained Fire outward.

Usage & Safety

How to use this formula and important safety information

Important Medical Disclaimer

The information provided here is for educational purposes only and is not intended as medical advice or to replace consultation with a qualified healthcare professional. This formula is a dietary supplement and has not been evaluated by the FDA. It is not intended to diagnose, treat, cure, or prevent any disease.

Always consult with a qualified healthcare provider, particularly if you are pregnant, nursing, have a medical condition, or are taking other medications. Discontinue use and consult your healthcare provider if you experience any adverse reactions.

Recommended Dosage

Instructions for safe storage and consumption

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Best Time to Take

Sip small amounts frequently throughout the day (the classical method), or take 2-3 times daily after meals to reduce potential stomach upset from the bitter, cold herbs.

Typical Duration

Acute use: 3-7 days, reassessed daily as this is a strong clearing formula not intended for extended use.

Dietary Advice

While taking this formula, avoid greasy, fried, and rich foods, as these generate internal Heat and Dampness that can worsen the condition and impede recovery. Spicy, warming foods (such as chili, ginger, lamb, and alcohol) should be strictly avoided, as they add Heat to an already Hot condition. Cold and raw foods should also be limited despite the Heat pattern, because the formula is already very cold in nature and excessive cold foods may further burden the Spleen and Stomach. Favor light, easily digestible foods such as congee (rice porridge), steamed vegetables, mung bean soup (which also clears Heat), pear, watermelon (in moderation), and chrysanthemum tea. Adequate fluid intake is important to prevent further drying of body fluids by the Heat-toxin. The classical administration method called for frequent small doses sipped throughout the day, which suggests eating small, light meals rather than large ones.

Modern Usage*

Pu Ji Xiao Du Yin is classified as a Heat-clearing formula and has the effects of clearing Heat, detoxifying, dispersing Wind, and expelling pathogens. It is primarily used to treat "Da Tou Wen" (a severe febrile disease with swelling of the head). Symptoms include chills and fever, redness, swelling, and burning pain of the head and face, difficulty opening the eyes, sore throat, dry tongue with thirst, a red tongue with a white and yellow coating, and a floating, rapid, and forceful pulse.
Clinically, it is often used to treat conditions such as erysipelas, mumps, acute tonsillitis, and lymphadenitis that are caused by Wind-Heat Toxins.

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Special Populations

Pregnancy

Use with caution during pregnancy. The formula contains Niu Bang Zi (Burdock Seed), which has a slippery, intestine-lubricating quality, and Bai Jiang Can (Silkworm), which has dispersing properties. Several herbs are strongly bitter and cold (Huang Qin at heavy dosage, Huang Lian, Ban Lan Gen), and prolonged or high-dose use of intensely cold formulas can potentially affect the fetus. While Huang Qin is classically used to calm the fetus, the overall formula is designed for short-term acute use in excess Heat conditions and is not appropriate for routine use during pregnancy. A qualified practitioner should evaluate whether the severity of the acute condition warrants use and may need to adjust dosages.

Breastfeeding

No specific classical prohibitions exist for breastfeeding. However, the formula is strongly bitter and cold, and its properties could theoretically transfer through breast milk and affect the infant's digestion, potentially causing loose stools. Huang Lian (Coptis) in particular is very bitter and cold and may be transmitted in small amounts through breast milk. If needed during breastfeeding for an acute condition, use should be kept to the shortest effective duration, at the lowest effective dose, and under practitioner supervision. Monitor the nursing infant for any signs of digestive disturbance such as loose stools or decreased appetite.

Pediatric Use

Pu Ji Xiao Du Yin has a long history of pediatric use, particularly for childhood mumps (epidemic parotitis), tonsillitis, and swollen lymph glands. Dosage should be reduced according to the child's age and weight: approximately one-third of the adult dose for children aged 3-6, and one-half for children aged 7-12. Children above 12 can take close to adult dosages. Because the formula is strongly bitter and cold, treatment duration should be kept short (typically 3-5 days). Closely monitor for digestive side effects such as reduced appetite, nausea, or loose stools, which are common in children due to their naturally delicate Spleen and Stomach Qi. The formula may be prepared as a concentrated granule dissolved in warm water with a small amount of honey to improve palatability (if the child is over one year old). Not recommended for infants under 1 year without direct specialist supervision.

Cautions & Warnings

Although this formula is typically safe for most individuals, it may cause side effects in some people. Pregnant women, nursing mothers, postpartum women, and those with liver disease should use the formula with caution.

As with any Chinese herbal remedy, it is advisable to seek guidance from a qualified TCM practitioner before beginning treatment.