Formula

Ding Xian Wan

定痫丸

Properties

Phlegm-resolving formulas · Slightly Cool

Key Ingredients

Tian Ma, Dan Nan Xing

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

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$117.00 ($1.17/g)
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About This Formula*

Traditional Chinese Medicine background and properties

Formula Description*

A classical formula used to clear stubborn phlegm, calm internal wind, open the mind's orifices, and settle the spirit. It is the primary TCM formula for seizure disorders caused by wind and phlegm combined with heat, presenting as sudden collapse, convulsions, upward-rolling eyes, foaming at the mouth, and phlegm-rattling in the throat.

Formula Category*

Main Actions*

  • Transforms Wind-Phlegm and Stops Spasms
  • Opens the Orifices and Revives Consciousness
  • Calms the Spirit and Settles Fright
  • Clears Heat and Transforms Phlegm
  • Calms the Liver and Stops Convulsions

TCM Patterns*

In TCM, symptoms don't appear randomly — they cluster into recognizable patterns of disharmony that reveal what's out of balance in the body. Ding Xian Wan is traditionally associated with these specific patterns.

The following describes this formula's classification within Traditional Chinese Medicine theory and is provided for educational purposes only.

Why Ding Xian Wan addresses this pattern

This is the primary pattern Ding Xian Wan was designed to treat. In this pattern, internal Liver wind stirs up accumulated phlegm, and the two pathogenic factors combine to block the brain's orifices, causing sudden loss of consciousness and convulsions. The formula's large contingent of phlegm-transforming herbs (Dan Nan Xing, Chuan Bei Mu, Ban Xia, Chen Pi, Fu Ling, Zhu Li) work alongside powerful wind-extinguishing substances (Tian Ma, Quan Xie, Jiang Can) to address both halves of this wind-phlegm complex simultaneously. Shi Chang Pu and Yuan Zhi then open the blocked orifices, while Hu Po, Zhu Sha, and Fu Shen settle the disturbed spirit once the obstructing phlegm is cleared.

A practitioner would look for one or more of these signs

Seizures

Sudden onset, falling to the ground

Convulsions

Tonic-clonic limb convulsions

Loss Of Consciousness

Sudden collapse with loss of awareness

Excessive Phlegm

Foaming at mouth, phlegm rattling in throat

Limb Twitching

Eyes rolling upward

Involuntary Vocalization

Sudden shrieking or animal-like cries

How It Addresses the Root Cause*

Ding Xian Wan addresses a pattern known as Wind-Phlegm with brewing Heat obstructing the brain's clear orifices (风痰蕴热,上蒙脑窍). In this pattern, Phlegm has accumulated internally over time, often rooted in Spleen weakness failing to properly transform fluids, or in emotional disturbance (fright, anger, or chronic stress) disrupting the Liver's smooth flow of Qi. When a trigger event occurs, such as emotional upset, fright, or overexertion, the Qi mechanism becomes chaotic: Liver Yang flares upward and transforms into internal Wind, which stirs up the accumulated Phlegm. This Phlegm, now carried by Wind, surges upward and blocks the brain's sensory orifices, causing the sudden loss of consciousness and collapse that characterize seizure episodes.

The internal Wind also accounts for the convulsions, muscle spasms, and upward-rolling eyes, as Wind by nature causes movement and trembling. The Phlegm congesting the throat produces the characteristic gurgling sound and foaming at the mouth. Over time, repeated flare-ups of Wind-Phlegm generate Heat, creating a self-reinforcing cycle: Heat condenses fluids into thicker Phlegm, and Phlegm obstruction further impedes Qi flow and breeds more Heat. The tongue coating (white-greasy tending slightly yellow) and pulse (wiry and slippery, slightly rapid) reflect exactly this combination of Wind, Phlegm, and simmering Heat.

Because the root pathology involves both the tangible substance of Phlegm and the dynamic force of internal Wind, with Heat as a complicating factor and the spirit (Shen) being disturbed by the obstruction of the brain orifices, the treatment must address all four aspects simultaneously: scour the Phlegm, extinguish the Wind, clear the Heat, and calm the spirit. This is precisely the therapeutic logic of Ding Xian Wan.

Formula Properties*

Temperature

Slightly Cool

Taste Profile

Predominantly bitter and sweet with acrid and salty notes. Bitter to clear Heat and drain Phlegm downward, sweet to tonify and harmonize, acrid to open orifices and disperse, salty (from mineral/animal substances) to soften, settle, and anchor the spirit.

Target Organs
Heart Liver Spleen Lungs Brain
Channels Entered
Heart Liver Spleen Lung Stomach

Formula Origin

Yi Xue Xin Wu (医学心悟, Medical Revelations) by Cheng Guo-peng (程国彭)

This is just partial information on the formula's TCM properties. More detailed information is available on the formula's dedicated page

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Product Details

Manufacturing, supplier, and product specifications

Product Type

Granules

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Supplier Information

Treasure of the East

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Ingredients in Ding Xian Wan

Detailed information about each herb in Ding Xian Wan and their roles

Kings
Deputies
Assistants
Envoys
Tian Ma
Tian Ma

Gastrodia root

Dosage: 30g

Temperature Neutral
Taste Sweet (甘 gān)
Organ Affinity Liver
Parts Used Tuber (块茎 kuài jīng / 块根 kuài gēn)
Role in Ding Xian Wan

Calms Liver wind and stops spasms. As a key wind-extinguishing herb, it directly addresses the internal Liver wind that drives the convulsions and sudden collapse characteristic of seizure episodes.

Dan Nan Xing
Dan Nan Xing

Bile Arisaema

Dosage: 15g

Temperature Cool
Taste Bitter (苦 kǔ), Acrid / Pungent (辛 xīn)
Organ Affinity Lungs, Liver, Spleen
Parts Used Processed / Derived product (加工品 jiā gōng pǐn)
Role in Ding Xian Wan

Clears heat, transforms phlegm, calms wind, and resolves spasms. The bile processing makes it cold in nature and specifically suited to clearing phlegm-heat that clouds the brain's orifices, while simultaneously helping to extinguish wind.

Chuan Bei Mu
Chuan Bei Mu

Sichuan fritillary bulb

Dosage: 30g

Temperature Slightly Cool
Taste Bitter (苦 kǔ), Sweet (甘 gān)
Organ Affinity Lungs, Heart
Parts Used Bulb (鳞茎 lín jīng)
Role in Ding Xian Wan

Clears heat and transforms phlegm-heat, opens constraint, and disperses nodules. Its cool, moistening nature also helps protect Yin from being damaged by the acrid wind-extinguishing and drying herbs in the formula.

Quan Xie
Quan Xie

Scorpion

Dosage: 15g

Temperature Neutral
Taste Acrid / Pungent (辛 xīn), Salty (咸 xián)
Organ Affinity Liver
Parts Used Animal — whole (全虫 quán chóng)
Role in Ding Xian Wan

A powerful wind-extinguishing and spasm-stopping insect substance that penetrates deep into the channels to unblock collaterals and arrest convulsions.

Jiang Can
Jiang Can

Silkworm

Dosage: 15g

Temperature Neutral
Taste Acrid / Pungent (辛 xīn), Salty (咸 xián)
Organ Affinity Liver, Lungs, Stomach
Parts Used Animal — whole (全虫 quán chóng)
Role in Ding Xian Wan

Extinguishes wind and stops spasms while also transforming phlegm and softening hardness. Complements Tian Ma and Quan Xie in addressing the wind-phlegm complex.

Ban Xia
Ban Xia

Pinellia rhizome

Dosage: 30g

Temperature Warm
Taste Acrid / Pungent (辛 xīn)
Organ Affinity Spleen, Stomach, Lungs
Parts Used Tuber (块茎 kuài jīng / 块根 kuài gēn)
Role in Ding Xian Wan

Dries dampness and transforms phlegm, directs rebellious Qi downward. Works alongside Chen Pi and Fu Ling in the manner of Er Chen Tang to address the underlying damp-phlegm accumulation.

Chen Pi
Chen Pi

Tangerine peel

Dosage: 21g

Temperature Warm
Taste Acrid / Pungent (辛 xīn), Bitter (苦 kǔ)
Organ Affinity Lungs, Spleen
Parts Used Peel / Rind (皮 pí / 果皮 guǒ pí)
Role in Ding Xian Wan

Regulates Qi and dries dampness to transform phlegm. When Qi flows smoothly, phlegm disperses more easily.

Fu Ling
Fu Ling

Poria

Dosage: 30g

Temperature Neutral
Taste Sweet (甘 gān), Bland (淡 dàn)
Organ Affinity Heart, Lungs, Spleen, Kidneys
Parts Used Fungus / Mushroom (菌类 jūn lèi)
Role in Ding Xian Wan

Strengthens the Spleen, leaches dampness, and eliminates the source of phlegm production. Addresses the root cause of phlegm generation by supporting healthy Spleen function.

Fu Shen
Fu Shen

Poria with Hostwood

Dosage: 30g

Temperature Neutral
Taste Sweet (甘 gān), Bland (淡 dàn)
Organ Affinity Heart, Spleen
Parts Used Fungus / Mushroom (菌类 jūn lèi)
Role in Ding Xian Wan

Calms the spirit and quiets the Heart while also helping to transform phlegm. Bridges the phlegm-clearing and spirit-settling aspects of the formula.

Shi Chang Pu
Shi Chang Pu

Acorus rhizome

Dosage: 15g

Temperature Warm
Taste Acrid / Pungent (辛 xīn), Bitter (苦 kǔ), Aromatic (芳香 fāng xiāng)
Organ Affinity Heart, Stomach
Parts Used Rhizome (根茎 gēn jīng)
Role in Ding Xian Wan

Opens the orifices, transforms phlegm, and awakens the spirit. Directly targets the clouding of consciousness that occurs when phlegm obstructs the brain's sensory orifices.

Yuan Zhi
Yuan Zhi

Polygala root

Dosage: 21g

Temperature Warm
Taste Bitter (苦 kǔ), Acrid / Pungent (辛 xīn)
Organ Affinity Heart, Kidneys, Lungs
Parts Used Root (根 gēn)
Role in Ding Xian Wan

Calms the spirit, opens the orifices, and expels phlegm. Pairs with Shi Chang Pu to powerfully clear phlegm from the Heart and restore mental clarity.

Dan Shen
Dan Shen

Red sage root

Dosage: 60g

Temperature Slightly Cool
Taste Bitter (苦 kǔ)
Organ Affinity Heart, Liver, Pericardium
Parts Used Root (根 gēn)
Role in Ding Xian Wan

Cools the Heart and calms the spirit, while activating Blood circulation. Its cool nature helps clear Heart heat that contributes to restlessness and disturbed consciousness.

Mai Dong
Mai Dong

Ophiopogon root

Dosage: 60g

Temperature Slightly Cool
Taste Sweet (甘 gān), Bitter (苦 kǔ)
Organ Affinity Heart, Lungs, Stomach
Parts Used Tuber (块茎 kuài jīng / 块根 kuài gēn)
Role in Ding Xian Wan

Nourishes Yin, moistens dryness, and clears Heart heat. Its sweet, moistening nature prevents the many acrid, drying, and wind-extinguishing herbs from damaging Yin fluids.

Hu Po
Hu Po

Amber

Dosage: 15g

Temperature Neutral
Taste Sweet (甘 gān), Bland (淡 dàn)
Organ Affinity Heart, Liver, Urinary Bladder
Parts Used Resin / Sap (树脂 shù zhī / 汁 zhī)
Role in Ding Xian Wan

Settles the Heart and calms the spirit with its heavy, anchoring nature. Provides mineral-based sedation to stabilize the disturbed spirit during and between seizure episodes.

Zhu Sha
Zhu Sha

Cinnabar

Dosage: 9g

Temperature Cool
Taste Sweet (甘 gān)
Organ Affinity Heart
Parts Used Mineral (矿物 kuàng wù)
Role in Ding Xian Wan

Heavily sedates the Heart, calms the spirit, and clears Heart heat. Used as a coating for the pills, providing powerful mineral-based calming of disturbed consciousness.

Gan Cao
Gan Cao

Licorice root

Dosage: 120g (as paste for pill binding)

Temperature Neutral
Taste Sweet (甘 gān)
Organ Affinity Heart, Lungs, Spleen, Stomach
Parts Used Root (根 gēn)
Role in Ding Xian Wan

Harmonizes all the other herbs in the formula, moderates the toxicity of substances like Quan Xie and Ban Xia, and protects the Stomach. Cooked into a paste to bind the pills.

Modern Research (2 studies)

  • Review: New advances in Traditional Chinese Medicine interventions for epilepsy (2025)
  • Meta-analysis: Efficacy and safety of traditional Chinese medicine for the treatment of epilepsy (2023)
See all research on the formula page

Usage & Safety

How to use this formula and important safety information

Important Medical Disclaimer

The information provided here is for educational purposes only and is not intended as medical advice or to replace consultation with a qualified healthcare professional. This formula is a dietary supplement and has not been evaluated by the FDA. It is not intended to diagnose, treat, cure, or prevent any disease.

Always consult with a qualified healthcare provider, particularly if you are pregnant, nursing, have a medical condition, or are taking other medications. Discontinue use and consult your healthcare provider if you experience any adverse reactions.

Recommended Dosage

Instructions for safe storage and consumption

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Best Time to Take

Twice daily, morning and evening, taken with warm water on a relatively empty stomach (30-60 minutes before meals or 1-2 hours after meals).

Typical Duration

Typically prescribed in courses of 4-12 weeks as pill form, with periodic reassessment. Duration depends on seizure frequency and response. Long-term use requires monitoring due to Cinnabar content.

Dietary Advice

While taking this formula, avoid greasy, deep-fried, and rich foods, as these promote Phlegm production and directly counteract the formula's Phlegm-clearing action. Spicy, hot foods (chili peppers, strong alcohol, excessive garlic) should also be limited, as they may aggravate internal Heat and Liver Wind. Avoid stimulants such as strong coffee and excessive tea, which can lower the seizure threshold and disturb the spirit. Favor light, easily digestible foods: congee, steamed vegetables, mung bean soup, and foods that support the Spleen's digestive function. Celery, chrysanthemum tea, and lotus seed are traditionally considered helpful for calming the Liver and settling the spirit. Adequate hydration supports the body's fluid metabolism and helps prevent Phlegm from re-accumulating. Regular mealtimes and moderate portions are important, as overeating or irregular eating can impair Spleen function and generate more Phlegm.

Special Populations

Pregnancy

Contraindicated in pregnancy. This formula contains several substances of concern: 1. Zhu Sha (Cinnabar, mercuric sulfide): Listed as prohibited during pregnancy in the Chinese Pharmacopoeia. Animal studies show reproductive toxicity at doses close to or within the clinical range, including increased pre-implantation embryo loss and decreased live fetus count. 2. Quan Xie (Scorpion): A toxic animal-derived substance traditionally classified as contraindicated in pregnancy. 3. Ban Xia (Pinellia): Traditionally listed among pregnancy-caution herbs due to its acrid, descending nature. 4. Jiang Can (Bombyx Batryticatus): An insect-derived substance with wind-extinguishing properties, traditionally used with caution in pregnancy. Pregnant women with seizure disorders should work with both a qualified TCM practitioner and their obstetrician to find safe alternatives.

Breastfeeding

Use with caution during breastfeeding. The primary concern is Zhu Sha (Cinnabar), which contains mercuric sulfide. Mercury can accumulate in the body and has the potential to transfer into breast milk. Even small amounts of mercury exposure are concerning for nursing infants, whose developing nervous systems are particularly vulnerable to heavy metal toxicity. Quan Xie (Scorpion) is a toxic substance whose components could theoretically pass into breast milk, though specific data on this are limited. If a breastfeeding mother requires treatment for seizure disorders, a practitioner should consider modifying the formula to remove or substitute Zhu Sha and Quan Xie, or explore alternative formulas. The risks and benefits should be carefully evaluated on a case-by-case basis.

Pediatric Use

The original text explicitly states that this formula treats seizure disorders in men, women, and children (男、妇、小儿痫症并皆治之). However, important considerations apply: 1. Dosage: Pediatric doses should be significantly reduced according to age and body weight. A general guideline is one-third to one-half of the adult dose for children aged 6-12, and one-quarter for children under 6, but this must be individualized by a qualified practitioner. 2. Zhu Sha (Cinnabar) caution: The Chinese Pharmacopoeia advises caution with Cinnabar in children due to mercury content. Many modern practitioners reduce or omit the Cinnabar when prescribing for children, or limit the duration of use strictly. 3. Quan Xie (Scorpion): Dosage of this toxic substance must be carefully controlled in children. 4. Duration: Courses should be kept as short as clinically effective, with regular monitoring, especially for any signs of mercury-related side effects (irritability, digestive disturbance, skin rash). 5. Modern pediatric epilepsy management typically involves this formula as an adjunct to conventional anti-seizure medications, not as sole therapy, particularly in children with frequent or severe seizures.

Cautions & Warnings

Ding Xian Wan is typically safe for most individuals, but it can lead to side effects in some cases. Pregnant, nursing, or postpartum women, as well as those with liver conditions, should use this formula cautiously and preferably under professional supervision.

As with any Chinese herbal remedy, it is advisable to seek guidance from a qualified Traditional Chinese Medicine (TCM) practitioner before beginning treatment with this formula.