Formula

Bu Zhong Yi Qi Tang

Tonify the Middle and Increase Qi decoction | 补中益气汤

Also known as:

Energy Booster decoction , Tonify the Middle to Augment the Qi Decoction , Ginseng and Astragalus , Central Qi Tonic

Properties

Qi-tonifying formulas · Slightly Warm

Key Ingredients

Huang Qi

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

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About This Formula

Traditional Chinese Medicine background and properties

Formula Description

A foundational formula for strengthening the digestive system and lifting the body's Qi when it has sunk or become depleted. It is commonly used for persistent fatigue, poor appetite, loose stools, and conditions involving organ prolapse (such as rectal or uterine prolapse) caused by weakness of the Spleen and Stomach. It is one of the most widely used formulas in all of Chinese medicine.

Formula Category

Main Actions

  • Tonifies the Middle and Augments Qi
  • Raises sunken Yang
  • Lifts Sunken Qi
  • Strengthens the Spleen
  • Clears Heat from deficiency (sweet-warm method)

TCM Patterns

In TCM, symptoms don't appear randomly — they cluster into recognizable patterns of disharmony that reveal what's out of balance in the body. Bu Zhong Yi Qi Tang is traditionally associated with these specific patterns.

The following describes this formula's classification within Traditional Chinese Medicine theory and is provided for educational purposes only.

Why Bu Zhong Yi Qi Tang addresses this pattern

Spleen Qi deficiency is the foundational pattern this formula addresses. When the Spleen is too weak to properly transport and transform food and fluids, the result is poor appetite, fatigue, loose stools, and a sallow complexion. The Spleen is the source of Qi and Blood for the entire body. Bu Zhong Yi Qi Tang directly targets this deficiency through its core group of Huang Qi, Ren Shen, Bai Zhu, and Zhi Gan Cao, which together powerfully restore the Spleen's function. Dang Gui supports Blood production that has faltered due to the weak Spleen, while Chen Pi ensures that the tonifying herbs do not overwhelm the already sluggish digestive system.

A practitioner would look for one or more of these signs

Eye Fatigue

Persistent tiredness worsened by exertion

Poor Appetite

Reduced desire to eat, especially for heavy foods

Loose Stools

Unformed or soft stools, not necessarily frequent

Shortness Of Breath

Shortness of breath and reluctance to speak

Spontaneous Sweat

Sweating without exertion or heat exposure

How It Addresses the Root Cause

Bu Zhong Yi Qi Tang addresses a condition where the Spleen and Stomach have been weakened by overwork, irregular eating, emotional strain, or prolonged illness. The Spleen and Stomach are the body's central "digestive engine" and the source of Qi and Blood production. When they become depleted, the body cannot extract and distribute nourishment from food properly. This leads to reduced appetite, loose stools, fatigue, a pale complexion, and a general sense of heaviness and weakness.

The Spleen also has a crucial "lifting" function in TCM: it holds organs in place and sends refined nutrients upward to the Lungs and Heart. When Spleen Qi becomes too weak to perform this upward support, a condition called "sinking of middle Qi" (中气下陷) develops. This manifests as organ prolapse (rectal prolapse, uterine prolapse, stomach prolapse), chronic diarrhea, and abnormal uterine bleeding. Additionally, when clear Yang sinks to the lower body and becomes trapped, it generates a distinctive low-grade fever. This fever is not caused by an external infection or by true excess Heat; rather, it arises from the failure of Qi to circulate properly. Because the skin's protective barrier (the Wei Qi) is also weakened, spontaneous sweating is common.

Li Dongyuan recognized that treating this fever with cold, bitter herbs (the standard approach for clearing Heat) would only further damage the already fragile Spleen and Stomach. Instead, his breakthrough insight was to use sweet, warm herbs to restore the middle, lift the sunken Yang, and thereby resolve the fever at its root: a strategy known as "clearing Heat with sweet warmth" (甘温除热).

Formula Properties

Temperature

Slightly Warm

Taste Profile

Predominantly sweet with mild bitter and pungent notes — sweet to tonify the Spleen and generate Qi, mildly pungent to move and raise Qi, and slightly bitter to promote drainage and prevent stagnation.

Target Organs
Spleen Stomach Lungs
Channels Entered
Spleen Stomach Lung Liver

Formula Origin

Nei Wai Shang Bian Huo Lun (内外伤辨惑论) by Li Dongyuan (李东垣)

This is just partial information on the formula's TCM properties. More detailed information is available on the formula's dedicated page

Ingredients in Bu Zhong Yi Qi Tang

Detailed information about each herb in Bu Zhong Yi Qi Tang and their roles

Kings
Deputies
Assistants
Envoys
Huang Qi
Huang Qi

Astragalus root

Dosage: 15 - 30g

Temperature Slightly Warm
Taste Sweet (甘 gān)
Organ Affinity Spleen, Lungs
Parts Used Root (根 gēn)
Role in Bu Zhong Yi Qi Tang

The chief herb of the formula. Sweet and slightly warm, it enters the Spleen and Lung channels to powerfully tonify the middle Qi, raise sunken Yang, and stabilize the exterior to stop spontaneous sweating. It addresses the core pathomechanism of Spleen Qi deficiency and sinking.

Ren Shen
Ren Shen

Ginseng root

Dosage: 6 - 15g

Temperature Slightly Warm
Taste Sweet (甘 gān), Bitter (苦 kǔ)
Organ Affinity Spleen, Lungs, Heart, Kidneys
Parts Used Root (根 gēn)
Role in Bu Zhong Yi Qi Tang

Strongly supplements the source Qi and supports the Spleen and Lung. Works synergistically with Huang Qi: while Huang Qi tonifies the exterior and surface Qi, Ren Shen replenishes the deep internal Qi of the five Zang organs. In modern practice, Dang Shen is often substituted for milder cases.

Bai Zhu
Bai Zhu

White Atractylodes rhizome

Dosage: 9 - 15g

Temperature Warm
Taste Bitter (苦 kǔ), Sweet (甘 gān)
Organ Affinity Spleen, Stomach
Parts Used Rhizome (根茎 gēn jīng)
Role in Bu Zhong Yi Qi Tang

Strengthens the Spleen and dries Dampness, supporting the Spleen's transport and transformation function. Together with Ren Shen and Zhi Gan Cao, it forms a strong Qi-tonifying core that ensures the source of Qi and Blood production remains robust.

Gan Cao
Gan Cao

Licorice root

Dosage: 6 - 9g

Temperature Neutral
Taste Sweet (甘 gān)
Organ Affinity Heart, Lungs, Spleen, Stomach
Parts Used Root (根 gēn)
Role in Bu Zhong Yi Qi Tang

Honey-prepared Licorice root that tonifies Spleen Qi, supplements the middle, and harmonizes the entire formula. Li Dongyuan considered the combination of Huang Qi, Ren Shen, and Zhi Gan Cao together to be the core group for clearing deficiency-type Heat.

Dang Gui
Dang Gui

Chinese Angelica root

Dosage: 3 - 10g

Temperature Warm
Taste Sweet (甘 gān), Acrid / Pungent (辛 xīn)
Organ Affinity Liver, Heart, Spleen
Parts Used Root (根 gēn)
Role in Bu Zhong Yi Qi Tang

Nourishes Blood and harmonizes the nutritive layer. Since Qi deficiency easily leads to Blood deficiency, Dang Gui ensures the newly generated Qi has Blood to anchor in. As the classical saying goes, 'Blood is the mother of Qi,' so supplementing Blood supports the overall Qi-tonifying strategy.

Chen Pi
Chen Pi

Tangerine peel

Dosage: 6 - 9g

Temperature Warm
Taste Acrid / Pungent (辛 xīn), Bitter (苦 kǔ)
Organ Affinity Lungs, Spleen
Parts Used Peel / Rind (皮 pí / 果皮 guǒ pí)
Role in Bu Zhong Yi Qi Tang

Regulates Qi and harmonizes the Stomach, preventing the rich tonifying herbs from causing stagnation or bloating. Its mild drying and Qi-moving properties ensure that the supplementation is properly absorbed rather than creating congestion in the middle.

Sheng Ma
Sheng Ma

Bugbane rhizome

Dosage: 3 - 6g

Temperature Slightly Cool
Taste Acrid / Pungent (辛 xīn), Sweet (甘 gān)
Organ Affinity Lungs, Spleen, Stomach, Large Intestine
Parts Used Rhizome (根茎 gēn jīng)
Role in Bu Zhong Yi Qi Tang

Used in a small dose to raise the clear Yang of the Yangming (Stomach) channel. It guides the Qi-tonifying herbs upward to lift sunken middle Qi back to its proper position. It also helps vent deficiency Heat outward. As Li Shizhen noted, it 'leads the Yangming clear Qi upward.'

Chai Hu
Chai Hu

Bupleurum root

Dosage: 3 - 6g

Temperature Slightly Cool
Taste Acrid / Pungent (辛 xīn), Bitter (苦 kǔ)
Organ Affinity Liver, Gallbladder, Lungs
Parts Used Root (根 gēn)
Role in Bu Zhong Yi Qi Tang

Used in a small dose to raise the clear Yang of the Shaoyang (Gallbladder) channel. Paired with Sheng Ma, it creates a bilateral ascending action that lifts the sunken Qi of both the Yangming and Shaoyang pathways, restoring the upward movement of the Spleen's clear Qi.

Modern Research (3 studies)

  • Systematic Review and Meta-Analysis of Buzhong Yiqi Tang for Stable COPD (2016)
  • Meta-Analysis of Modified Buzhong-Yiqi-Tang for Functional Constipation in Adults (2018)
See all research on the formula page

Usage & Safety

How to use this formula and important safety information

Important Medical Disclaimer

The information provided here is for educational purposes only and is not intended as medical advice or to replace consultation with a qualified healthcare professional. This formula is a dietary supplement and has not been evaluated by the FDA. It is not intended to diagnose, treat, cure, or prevent any disease.

Always consult with a qualified healthcare provider, particularly if you are pregnant, nursing, have a medical condition, or are taking other medications. Discontinue use and consult your healthcare provider if you experience any adverse reactions.

Recommended Dosage

Instructions for safe storage and consumption

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Best Time to Take

On an empty stomach, 30-60 minutes before meals, served slightly warm — traditionally taken in the morning or divided into morning and afternoon doses.

Typical Duration

Often taken for 2-8 weeks for chronic Qi deficiency and organ prolapse conditions; reassessed by a practitioner every 2-4 weeks. Shorter courses of 1-2 weeks may suffice for milder Qi deficiency with fatigue.

Dietary Advice

Avoid cold, raw, and greasy foods while taking this formula, as they burden the already weakened Spleen and Stomach. This includes ice-cold drinks, raw salads, excessive dairy, and deep-fried foods. Favour warm, easily digestible, nourishing foods such as congee (rice porridge), cooked root vegetables, soups, and well-cooked grains. Small, regular meals are better than large, heavy ones. Avoid excessive consumption of strongly spicy or pungent foods that can scatter Qi. The classical instructions specify taking the decoction on an empty stomach with slightly warm water, which supports optimal absorption.

Modern Usage

WHAT IS BU ZHONG YI QI TANG?
Bu Zhong Yi Qi Tang is a traditional Chinese herbal formula created by Li Dong Yuan around 1247 CE. Renowned for its rejuvenating properties, this formula is primarily used to strengthen the Spleen and Stomach, enhance Qi (vital energy), and restore the body's balance to support overall health and healing.

WHAT ARE THE BENEFITS OF BU ZHONG YI QI TANG?
Bu Zhong Yi Qi Tang is highly regarded as a potent Qi tonic in TCM. It fortifies the Qi of the Middle Burner and elevates sunken Yang. TCM practitioners frequently recommend Bu Zhong Yi Qi Tang for conditions such as fatigue, headaches, aversion to cold, spontaneous sweating, prolapsed organs, and other symptoms related to Qi Deficiency and Sinking Qi.

Special Populations

Pregnancy

Generally considered safe under professional guidance. Bu Zhong Yi Qi Tang is classically indicated for pregnancy-related conditions such as threatened miscarriage (胎动不安) due to Qi deficiency, suggesting its traditional use is supportive rather than harmful in pregnancy. However, the formula contains Dang Gui (Angelica sinensis), which has mild blood-moving properties, and Sheng Ma (Cimicifuga), which has an upward-lifting and slightly dispersing nature. Both herbs warrant caution in high-risk pregnancies. Pregnant women should only take this formula under the direct supervision of a qualified practitioner who can adjust the composition as needed.

Breastfeeding

Generally considered compatible with breastfeeding. The formula's Qi-tonifying and Spleen-strengthening actions may actually support milk production in women with postpartum Qi deficiency and insufficient lactation. None of the eight core herbs are known to produce harmful substances that transfer into breast milk at clinically significant levels. Gan Cao (Licorice) in the formula could theoretically cause mild fluid retention at high doses, but at the standard dosage used in this formula it is unlikely to pose a concern. Nevertheless, breastfeeding mothers should use the formula under professional guidance.

Pediatric Use

Bu Zhong Yi Qi Tang can be used in children under professional supervision, particularly for conditions related to Spleen Qi deficiency such as poor appetite, failure to thrive, chronic diarrhea, or rectal prolapse. Dosages should be significantly reduced according to the child's age and weight: generally one-quarter to one-third of the adult dose for children aged 3-6, and one-half of the adult dose for children aged 7-12. For very young children (under 3), use should be conservative and only under close practitioner guidance. The Ren Shen (Ginseng) component should be used with particular caution in young children, and Dang Shen (Codonopsis) is often substituted as a gentler alternative. The formula is available in patent pill and granule forms which make pediatric dosing easier.

Drug Interactions

Gan Cao (Glycyrrhiza / Licorice): This is the herb of greatest concern for drug interactions. Glycyrrhizin in licorice can cause pseudoaldosteronism (potassium loss and sodium/water retention). It may interact with: diuretics (especially potassium-depleting types like furosemide and hydrochlorothiazide), increasing the risk of hypokalemia; cardiac glycosides (e.g. digoxin), where hypokalemia can potentiate toxicity; corticosteroids, potentially enhancing their effects and side effects; and antihypertensive medications, by counteracting their blood-pressure-lowering effect through fluid retention.

Huang Qi (Astragalus): Has documented immunostimulatory effects and may theoretically interfere with immunosuppressant drugs (e.g. cyclosporine, tacrolimus, mycophenolate) used after organ transplantation or for autoimmune conditions. Patients on immunosuppressive therapy should avoid this formula or use it only under close medical supervision.

Dang Gui (Angelica sinensis): Has mild anticoagulant and antiplatelet activity. It may potentiate the effects of anticoagulant and antiplatelet drugs (e.g. warfarin, aspirin, clopidogrel), increasing bleeding risk. INR monitoring is advisable for patients on warfarin.

Ren Shen (Ginseng): May interact with MAO inhibitors and warfarin. It can also affect blood glucose levels, potentially interfering with antidiabetic medications.

Contraindications

Avoid

Yin deficiency with Heat signs (dry mouth, red tongue with little coating, night sweats). The warm, Qi-tonifying nature of this formula can further deplete Yin and aggravate Heat.

Avoid

Excess-type exterior conditions (chills and fever from external pathogenic invasion). Using tonifying herbs during an acute external attack can trap the pathogen inside the body.

Avoid

Excess patterns with food stagnation, abdominal fullness, and distension. The sweet, tonifying herbs can worsen stagnation and bloating.

Caution

Hypertension. The formula's Qi-raising and Yang-lifting properties may elevate blood pressure.

Avoid

Should not be taken concurrently with Li Lu (Veratrum) or preparations containing it, due to classical incompatibility with Ren Shen (Ginseng) and Gan Cao (Licorice) in the formula.

Caution

Liver Yang rising or Liver Fire flaring patterns with headache, dizziness, irritability, and a wiry forceful pulse. The upward-lifting action of Sheng Ma and Chai Hu may worsen these symptoms.

Cautions & Warnings

Although Bu Zhong Yi Qi Tang is typically safe for most individuals, it may cause side effects in some cases. People who suffer from migraines should avoid this formula. Pregnant women, nursing mothers, postpartum women, and individuals with liver disease should use Bu Zhong Yi Qi Tang with caution or under the guidance of a healthcare professional.

As with any Chinese herbal remedy, it is advisable to seek guidance from a qualified Traditional Chinese Medicine (TCM) practitioner before beginning treatment.

Product Details

Manufacturing, supplier, and product specifications

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Granules

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