Formula

Tian Wang Bu Xin Dan

Emperor Heart Formula | 天王补心丹

Also known as:

Emperor of Heaven's Special Pill to Tonify the Heart , Emperor of Heaven's Tonic Pill for the Mind , Ginseng and Zizyphus Combination , Emperor of Heaven

Properties

Spirit-calming formulas · Cool

Key Ingredients

Shu Di Huang

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

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About This Formula

Traditional Chinese Medicine background and properties

Formula Description

A classical formula for people who have trouble sleeping and feel restless due to overwork or prolonged mental exertion. It nourishes the body's Yin and Blood while calming the mind and clearing low-grade internal heat. Often used for insomnia with palpitations, forgetfulness, night sweats, and a general sense of mental exhaustion.

Formula Category

Main Actions

  • Nourishes Yin
  • Nourishes Blood
  • Tonifies Heart Qi
  • Calms the Spirit
  • Clears Deficiency Heat

TCM Patterns

In TCM, symptoms don't appear randomly — they cluster into recognizable patterns of disharmony that reveal what's out of balance in the body. Tian Wang Bu Xin Dan is traditionally associated with these specific patterns.

The following describes this formula's classification within Traditional Chinese Medicine theory and is provided for educational purposes only.

Why Tian Wang Bu Xin Dan addresses this pattern

This is the primary pattern the formula was designed for. When Heart and Kidney Yin are depleted (often from prolonged mental overwork, chronic stress, or extended illness), insufficient Kidney Water fails to ascend and cool Heart Fire. The resulting empty Heat rises to disturb the spirit (Shen), producing restlessness, insomnia, and palpitations. Sheng Di Huang addresses the root by simultaneously nourishing Heart Blood and Kidney Yin. Tian Men Dong and Mai Men Dong replenish Yin fluids. Xuan Shen and Dan Shen clear the empty Heat that accompanies this depletion. Suan Zao Ren, Bai Zi Ren, and Yuan Zhi directly calm the agitated spirit, while Wu Wei Zi contains the leakage of fluids through night sweats or nocturnal emissions.

A practitioner would look for one or more of these signs

Insomnia

Difficulty falling asleep or frequent waking, especially worsened by overwork

Palpitations

Heart pounding or fluttering, worse when anxious or at rest

Poor Memory

Forgetfulness and inability to concentrate

Night Sweats

Sweating during sleep, indicating Yin failing to contain fluids

Mouth Ulcers

Recurrent mouth or tongue sores from empty Heat rising

Constipation

Dry stools due to Yin deficiency failing to moisten the intestines

How It Addresses the Root Cause

The core disease mechanism addressed by Tian Wang Bu Xin Dan involves the depletion of Yin and Blood in the Heart and Kidneys, typically caused by prolonged worry, overthinking, or mental overwork. In TCM theory, the Heart houses the Spirit (Shen) and requires adequate Blood and Yin to anchor and nourish it. The Kidneys store Yin (Water) which normally ascends to cool and balance Heart Fire. When excessive mental exertion quietly consumes Yin and Blood over time, this dual support system breaks down.

With Heart Blood and Yin insufficient, the Spirit loses its residence and becomes restless, leading to palpitations, insomnia, poor memory, and mental fatigue. Simultaneously, the Kidney Yin that normally keeps Heart Fire in check is depleted. Without this balancing Water, deficiency Fire flares upward unchecked, producing heat signs in the palms and soles, mouth ulcers, dry throat, irritability, night sweats, and nocturnal emissions (as the uncontrolled Fire disturbs the Essence chamber). Dry stools result from Yin failing to moisten the intestines. A red tongue with little coating and a thin, rapid pulse confirm the pattern of Yin deficiency with internal Heat.

The formula intervenes by heavily nourishing Yin and Blood to rebuild the foundation (treating the root), while simultaneously calming the Spirit and gently clearing deficiency Fire (treating the branch). By restoring the Kidney Water that can subdue the upflaring Fire, and by replenishing the Heart Blood that anchors the Spirit, the Heart-Kidney axis is re-established and the Spirit finds peace again.

Formula Properties

Temperature

Cool

Taste Profile

Predominantly sweet and slightly bitter, with mild sour notes — sweet to nourish and tonify, bitter to gently clear Heat, sour to astringe and contain the Spirit.

Target Organs
Heart Kidneys
Channels Entered
Heart Kidney Lung

Formula Origin

Shè Shēng Mì Pōu (摄生秘剖, Secret Investigations into Obtaining Health) by Hóng Jī

This is just partial information on the formula's TCM properties. More detailed information is available on the formula's dedicated page

Ingredients in Tian Wang Bu Xin Dan

Detailed information about each herb in Tian Wang Bu Xin Dan and their roles

Kings
Deputies
Assistants
Envoys
Shu Di Huang
Shu Di Huang

Prepared Rehmannia root

Dosage: 15 - 30g

Temperature Slightly Warm
Taste Sweet (甘 gān)
Organ Affinity Liver, Kidneys
Parts Used Tuber (块茎 kuài jīng / 块根 kuài gēn)
Role in Tian Wang Bu Xin Dan

The chief herb, used at the highest dosage. Its sweet, cold nature enters the Heart and Kidney channels, simultaneously nourishing Heart Blood above and enriching Kidney Yin below. This addresses the root cause by 'strengthening Water to control Fire' (壮水制火), subduing the empty heat that disturbs the spirit.

Tian Men Dong
Tian Men Dong

Asparagus tuber

Dosage: 9 - 12g

Temperature Cold
Taste Sweet (甘 gān), Bitter (苦 kǔ)
Organ Affinity Lungs, Kidneys
Parts Used Tuber (块茎 kuài jīng / 块根 kuài gēn)
Role in Tian Wang Bu Xin Dan

Nourishes Yin and clears empty Heat in the Lung and Kidney channels, assisting the King herb in replenishing the Yin fluids that have been depleted.

Tian Men Dong
Tian Men Dong

Asparagus tuber

Dosage: 9 - 12g

Temperature Cold
Taste Sweet (甘 gān), Bitter (苦 kǔ)
Organ Affinity Lungs, Kidneys
Parts Used Tuber (块茎 kuài jīng / 块根 kuài gēn)
Role in Tian Wang Bu Xin Dan

Works together with Tian Men Dong to nourish Yin, generate fluids, and clear Heat. Together the 'two Dongs' moisten dryness in the upper body and calm irritability from Yin deficiency.

Suan Zao Ren
Suan Zao Ren

Sour jujube seed

Dosage: 9 - 12g

Temperature Neutral
Taste Sweet (甘 gān), Sour (酸 suān)
Organ Affinity Heart, Liver, Gallbladder
Parts Used Seed (种子 zhǒng zǐ / 子 zǐ / 仁 rén)
Role in Tian Wang Bu Xin Dan

Nourishes Heart Blood and calms the spirit. Its sour taste helps to astringe and preserve the Heart's scattered Qi, directly addressing insomnia and palpitations.

Bai Zi Ren
Bai Zi Ren

Arborvitae seed

Dosage: 9 - 12g

Temperature Neutral
Taste Sweet (甘 gān)
Organ Affinity Heart, Kidneys, Large Intestine
Parts Used Seed (种子 zhǒng zǐ / 子 zǐ / 仁 rén)
Role in Tian Wang Bu Xin Dan

Nourishes the Heart and calms the spirit while moistening the intestines to relieve the constipation that accompanies Yin deficiency. Pairs with Suan Zao Ren for a combined calming effect.

Dang Gui
Dang Gui

Chinese Angelica root

Dosage: 9 - 12g

Temperature Warm
Taste Sweet (甘 gān), Acrid / Pungent (辛 xīn)
Organ Affinity Liver, Heart, Spleen
Parts Used Root (根 gēn)
Role in Tian Wang Bu Xin Dan

Tonifies and invigorates Blood, lubricates the intestines for dry stools. Together with Dang Gui's moving nature, it ensures the Blood-nourishing effect is not stagnating.

Ren Shen
Ren Shen

Ginseng root

Dosage: 3 - 6g

Temperature Slightly Warm
Taste Sweet (甘 gān), Bitter (苦 kǔ)
Organ Affinity Spleen, Lungs, Heart, Kidneys
Parts Used Root (根 gēn)
Role in Tian Wang Bu Xin Dan

Powerfully tonifies Heart Qi so that Qi can generate Blood (气旺血生). Also calms the spirit and strengthens mental function, addressing the fatigue and forgetfulness.

Fu Ling
Fu Ling

Poria

Dosage: 3 - 6g

Temperature Neutral
Taste Sweet (甘 gān), Bland (淡 dàn)
Organ Affinity Heart, Lungs, Spleen, Kidneys
Parts Used Fungus / Mushroom (菌类 jūn lèi)
Role in Tian Wang Bu Xin Dan

Tonifies the Spleen and calms the spirit. Helps transport Dampness to prevent the many rich, Yin-nourishing herbs from causing stagnation.

Wu Wei Zi
Wu Wei Zi

Schisandra berry

Dosage: 3 - 6g

Temperature Warm
Taste Sour (酸 suān), Sweet (甘 gān)
Organ Affinity Lungs, Heart, Kidneys
Parts Used Fruit (果 guǒ / 果实 guǒ shí)
Role in Tian Wang Bu Xin Dan

Its sour, astringent nature contains and consolidates Heart Qi, preventing further leakage and scattering of Yin fluids. Also calms the spirit and prevents night sweats.

Xuan Shen
Xuan Shen

Figwort root

Dosage: 3 - 6g

Temperature Cold
Taste Sweet (甘 gān), Bitter (苦 kǔ), Salty (咸 xián)
Organ Affinity Lungs, Stomach, Kidneys
Parts Used Root (根 gēn)
Role in Tian Wang Bu Xin Dan

Nourishes Yin and quenches Fire, especially clearing the upward-flaring empty heat that causes mouth sores and throat dryness. Supports the King herb's water-nourishing strategy.

Dan Shen
Dan Shen

Red sage root

Dosage: 3 - 6g

Temperature Slightly Cool
Taste Bitter (苦 kǔ)
Organ Affinity Heart, Liver, Pericardium
Parts Used Root (根 gēn)
Role in Tian Wang Bu Xin Dan

Clears Heat from the Blood and mildly invigorates Blood circulation. This prevents the rich tonifying herbs from causing Blood stasis, ensuring smooth generation of new Heart Blood.

Yuan Zhi
Yuan Zhi

Polygala root

Dosage: 3 - 6g

Temperature Warm
Taste Bitter (苦 kǔ), Acrid / Pungent (辛 xīn)
Organ Affinity Heart, Kidneys, Lungs
Parts Used Root (根 gēn)
Role in Tian Wang Bu Xin Dan

Calms the spirit and facilitates communication between the Heart and Kidneys. Also helps to open the Heart orifices and clear mild Phlegm that can cloud mental clarity.

Jie Geng
Jie Geng

Balloon flower root

Dosage: 3 - 6g

Temperature Neutral
Taste Bitter (苦 kǔ), Acrid / Pungent (辛 xīn)
Organ Affinity Lungs
Parts Used Root (根 gēn)
Role in Tian Wang Bu Xin Dan

Acts as the channel-guiding herb (引经药), directing the formula's therapeutic actions upward to the Heart and chest region, preventing the herbs from descending too quickly.

Modern Research (3 studies)

  • Systematic Review and Meta-Analysis: Tian Wang Bu Xin Dan for Insomnia (2019)
  • RCT: TWBXD vs. Cognitive-Behavioral Therapy for Insomnia in Cancer Patients (2020)
See all research on the formula page

Usage & Safety

How to use this formula and important safety information

Important Medical Disclaimer

The information provided here is for educational purposes only and is not intended as medical advice or to replace consultation with a qualified healthcare professional. This formula is a dietary supplement and has not been evaluated by the FDA. It is not intended to diagnose, treat, cure, or prevent any disease.

Always consult with a qualified healthcare provider, particularly if you are pregnant, nursing, have a medical condition, or are taking other medications. Discontinue use and consult your healthcare provider if you experience any adverse reactions.

Recommended Dosage

Instructions for safe storage and consumption

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Best Time to Take

At bedtime (临卧), traditionally swallowed with a decoction of bamboo leaves (竹叶) or longan fruit (龙眼肉) in warm water.

Typical Duration

Typically taken for 2–4 weeks as an initial course, then reassessed by a practitioner. May be continued for 4–8 weeks for chronic Yin deficiency insomnia, with periodic breaks.

Dietary Advice

Classical dietary prohibitions (食忌) for this formula include cilantro (胡荽), garlic, radish, raw fish, and strong alcohol, as these are considered to disrupt the formula's nourishing and Spirit-calming actions. While taking this formula, favour foods that nourish Yin and Blood, such as black sesame, mulberries, lotus seeds, lily bulb (bai he), pears, and lightly prepared soups. Avoid excessively spicy, greasy, or deep-fried foods, which generate internal Heat and counteract the formula's cooling, moistening strategy. Cold and raw foods should also be moderated if digestion is weak, since the formula is already cloying by nature.

Modern Usage

WHAT IS TIAN WANG BU XIN DAN?
Tian Wang Bu Xin Dan is a traditional Chinese herbal formula that originated during the Qing Dynasty. Celebrated for its soothing and restorative effects, it is also known as the "Heavenly Emperor’s Formula to Tonify the Heart." This formula is specifically designed to address Heart and Kidney Yin Deficiency.

WHAT ARE THE BENEFITS OF TIAN WANG BU XIN DAN?
Within the realm of Traditional Chinese Medicine (TCM), Tian Wang Bu Xin Dan is utilized to nourish both Blood and Yin, thereby harmonizing the Heart-Kidney connection. It is frequently prescribed for a range of mental, emotional, cognitive, and physical ailments, such as anxiety, insomnia, memory lapses, palpitations, night sweats, and hot flashes.

Special Populations

Pregnancy

Use with caution during pregnancy. The traditional formulation includes Zhu Sha (cinnabar) as a pill coating, which contains mercury sulfide and is contraindicated in pregnancy due to potential teratogenic and hepatotoxic effects. Even in modern cinnabar-free versions, the formula contains Dang Gui (Angelica sinensis), which has mild Blood-moving properties that theoretically could stimulate uterine activity. Additionally, the heavily Yin-nourishing, cooling nature of the formula (with large doses of Sheng Di Huang, Tian Men Dong, and Mai Men Dong) may not be appropriate for pregnant women with Spleen deficiency. A qualified practitioner should assess individual suitability before use.

Breastfeeding

Caution is advised during breastfeeding. The primary concern is with traditional formulations that include Zhu Sha (cinnabar) as a pill coating. Mercury from cinnabar can potentially transfer into breast milk and pose a risk to the infant's developing nervous system, liver, and kidneys. Modern manufactured versions often omit cinnabar, which reduces this concern. The remaining herbal ingredients are generally considered gentle, but the formula's strong Yin-nourishing, cooling properties could theoretically affect the quality of breast milk or cause digestive upset in a nursing mother with Spleen weakness. A practitioner should evaluate the specific formulation and the mother's constitution before recommending use during lactation.

Pediatric Use

This formula is occasionally used in adolescents (typically age 12 and above) for study-related insomnia or anxiety with clear signs of Yin deficiency. Dosage should be reduced to roughly one-third to one-half of the adult dose, adjusted by body weight and age. It is generally not suitable for young children, as their constitutions tend toward Spleen weakness, and the heavy, Yin-nourishing ingredients can easily impair digestion. Any formulation containing Zhu Sha (cinnabar) should be strictly avoided in children due to their increased vulnerability to mercury toxicity. A qualified practitioner should supervise pediatric use.

Drug Interactions

Anticoagulants and antiplatelet drugs: Dan Shen (Salvia miltiorrhiza) and Dang Gui (Angelica sinensis) in this formula both have Blood-activating properties. Dan Shen in particular is well-documented to potentiate the effects of warfarin, increasing INR and bleeding risk. Concurrent use with warfarin, heparin, aspirin, or clopidogrel requires close monitoring.

Sedatives and CNS depressants: Several herbs in this formula (Suan Zao Ren, Bai Zi Ren, Fu Ling, Yuan Zhi) have mild sedative actions. When combined with benzodiazepines, barbiturates, or other sedative-hypnotic medications, there may be additive drowsiness or excessive sedation.

Digoxin and cardiac glycosides: Sheng Di Huang (Rehmannia) and Xuan Shen (Scrophularia) have known cardiac-active glycoside-like compounds. Theoretical interactions with digoxin may alter serum levels or cardiac effects, warranting caution and monitoring.

Antihypertensives: Preclinical research has shown that this formula may have mild hypotensive and vasorelaxant effects. Combined use with antihypertensive drugs could result in additive blood pressure lowering.

Cinnabar (Zhu Sha) concerns: Traditional formulations coated with cinnabar (mercury sulfide) can interact with any drugs metabolised by the liver or kidneys, as mercury accumulation impairs these organs. Cinnabar-containing versions should never be combined with other hepatotoxic or nephrotoxic drugs.

Contraindications

Caution

Spleen and Stomach deficiency with poor appetite, loose stools, or abdominal bloating. This formula is heavily weighted toward rich, Yin-nourishing herbs that are hard to digest and can worsen Dampness or impair an already weak digestive system.

Caution

Phlegm-Dampness obstruction. The cloying, moistening nature of the formula's many Yin tonics can aggravate Phlegm and Dampness, worsening symptoms like heavy-headedness, chest stuffiness, or copious phlegm.

Caution

Insomnia or palpitations due to excess-type patterns such as Liver Fire, Phlegm-Fire, or Food Stagnation. This formula treats deficiency-based restlessness and is inappropriate for excess conditions.

Avoid

Long-term continuous use in formulations containing Zhu Sha (cinnabar) as a coating. Cinnabar contains mercury sulfide and can cause cumulative toxicity to liver and kidneys. Modern preparations often omit it. If present, treatment courses should generally not exceed 14 days without monitoring liver and kidney function.

Avoid

Hepatic or renal impairment when using formulations containing Zhu Sha (cinnabar). Mercury-containing minerals are contraindicated in patients with compromised liver or kidney function.

Cautions & Warnings

Although Tian Wang Bu Xin Dan is typically safe for most individuals, some people may experience side effects. Pregnant women, nursing mothers, postpartum women, and individuals with liver disease should use Tian Wang Bu Xin Dan with caution or avoid it altogether.

As with any Chinese herbal remedy, it is advisable to seek guidance from a qualified Traditional Chinese Medicine (TCM) practitioner before beginning treatment.

Product Details

Manufacturing, supplier, and product specifications

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Granules

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