Formula

Jiang Zhi Yin

降脂饮

Also known as:

Crataegus Combination , Lipid Balance drink , Reduce Lipid formula

Properties

Phlegm-resolving formulas · Cool

Key Ingredients

Shan Zha

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

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About This Formula

Traditional Chinese Medicine background and properties

Formula Description

A modern TCM formula designed to support healthy cholesterol and lipid balance. It works by dissolving food stagnation (especially from rich, fatty diets), promoting blood circulation, draining dampness, and gently clearing accumulated turbidity from the body. It is commonly used for people with high cholesterol, fatty liver, or metabolic imbalances related to diet and lifestyle.

Formula Category

Main Actions

  • Resolves Phlegm and Disperses Accumulation
  • Promotes Digestion and Resolves Food Stagnation
  • Invigorates Blood and Dispels Stasis
  • Clears Damp-Heat
  • Soothes the Liver and Regulates Qi
  • Drains Dampness

TCM Patterns

In TCM, symptoms don't appear randomly — they cluster into recognizable patterns of disharmony that reveal what's out of balance in the body. Jiang Zhi Yin is traditionally associated with these specific patterns.

The following describes this formula's classification within Traditional Chinese Medicine theory and is provided for educational purposes only.

Why Jiang Zhi Yin addresses this pattern

In TCM, elevated blood lipids are often understood as an accumulation of turbid phlegm and dampness within the blood vessels and tissues. When the Spleen fails to properly transform and transport fluids and nutrients, dampness accumulates and over time condenses into phlegm. This turbid phlegm circulates in the blood, creating what modern medicine recognizes as high cholesterol and triglycerides. Jiang Zhi Yin addresses this pattern through multiple pathways: Shan Zha dissolves food-derived turbidity at its source in the digestive tract, Yi Yi Ren strengthens the Spleen to correct the root cause of dampness production, Ze Xie and Yin Chen drain dampness through the urinary and hepatobiliary routes, and Da Huang pushes turbid waste downward and out through the bowels.

A practitioner would look for one or more of these signs

Hyperlipidemia

Elevated cholesterol or triglycerides

Obesity

Overweight, especially abdominal

Dyspepsia

Bloating and fullness after meals

Eye Fatigue

Heaviness and fatigue in the limbs

Nausea

Nausea or greasy taste in mouth

How It Addresses the Root Cause

In TCM understanding, elevated blood lipids (hyperlipidemia) are not viewed as a standalone disease but as a manifestation of deeper imbalance, primarily involving the accumulation of Phlegm-Turbidity (痰浊) and Blood stasis (血瘀) in the vessels and tissues. The disease logic begins with the Spleen and Liver.

The Spleen is responsible for transforming and transporting the essence of food and water. When Spleen function weakens, whether from overindulgence in rich, greasy foods, sedentary lifestyle, or constitutional factors, it can no longer properly process fluids and nutrients. These unprocessed substances congeal into Dampness, which over time thickens into Phlegm-Turbidity. This "turbid fat" (脂浊) accumulates in the blood and tissues, corresponding closely to what modern medicine recognizes as elevated cholesterol and triglycerides.

Simultaneously, the Liver governs the smooth flow of Qi throughout the body. Emotional stress, frustration, or long-standing metabolic stagnation can cause Liver Qi to become constrained. When Qi stagnates, Blood circulation also slows, eventually leading to Blood stasis. Furthermore, stagnant Liver Qi impairs the Spleen's transformative function (the Liver "overacting" on the Spleen), worsening Phlegm-Dampness production. Over time, Phlegm and stasis bind together in the vessels, creating the sticky, obstructive pathology that underlies atherosclerosis and cardiovascular risk. Some patients also develop Damp-Heat as stagnant Phlegm and stasis generate pathological heat, or the Liver and Kidneys become depleted, adding a deficiency dimension to what is primarily an excess condition.

Formula Properties

Temperature

Cool

Taste Profile

Predominantly sour, bitter, and bland. Sour (Shan Zha) to digest food stagnation, bitter (Da Huang, Hu Zhang, Yin Chen, Yu Jin, Chai Hu) to drain Dampness and clear Heat, bland (Ze Xie, Yi Yi Ren) to leach out Dampness through urination.

Target Organs
Liver Spleen Stomach Large Intestine Kidneys
Channels Entered
Liver Spleen Stomach Large Intestine Kidney Gallbladder Bladder

Formula Origin

Modern clinical formula (contemporary TCM hospital formulation)

This is just partial information on the formula's TCM properties. More detailed information is available on the formula's dedicated page

Ingredients in Jiang Zhi Yin

Detailed information about each herb in Jiang Zhi Yin and their roles

Kings
Deputies
Assistants
Envoys
Shan Zha
Shan Zha

Hawthorn fruit

Dosage: 15 - 30g

Temperature Slightly Warm
Taste Sour (酸 suān), Sweet (甘 gān)
Organ Affinity Spleen, Stomach, Liver
Parts Used Fruit (果 guǒ / 果实 guǒ shí)
Role in Jiang Zhi Yin

The chief herb of the formula. Shan Zha (Hawthorn Fruit) powerfully dissolves food stagnation, especially from greasy and fatty foods. It invigorates blood circulation, transforms accumulations, and has well-documented modern lipid-lowering effects. It directly addresses the core therapeutic target of reducing turbid lipids.

Jue Ming Zi
Jue Ming Zi

Cassia seed

Dosage: 9 - 15g

Temperature Slightly Cool
Taste Sweet (甘 gān), Bitter (苦 kǔ), Salty (咸 xián)
Organ Affinity Liver, Large Intestine
Parts Used Seed (种子 zhǒng zǐ / 子 zǐ / 仁 rén)
Role in Jiang Zhi Yin

Clears Liver Heat, brightens the eyes, and moistens the intestines to promote bowel movement. Strongly synergizes with Shan Zha to lower lipids. Dry-frying moderates its cold nature while retaining its lipid-lowering properties.

He Shou Wu
He Shou Wu

Fleeceflower Root

Dosage: 9 - 15g

Temperature Slightly Warm
Taste Bitter (苦 kǔ), Sweet (甘 gān), Astringent (涩 sè)
Organ Affinity Liver, Kidneys
Parts Used Tuber (块茎 kuài jīng / 块根 kuài gēn)
Role in Jiang Zhi Yin

Tonifies Liver and Kidney, nourishes Blood and Essence. The processed form is used to provide a nourishing and stabilizing counterbalance to the many draining herbs in this formula, preventing excessive depletion. It also has documented cholesterol-regulating properties.

Hu Zhang
Hu Zhang

Giant Knotweed Rhizome

Dosage: 9 - 15g

Temperature Slightly Cool
Taste Bitter (苦 kǔ)
Organ Affinity Liver, Gallbladder, Lungs
Parts Used Rhizome (根茎 gēn jīng)
Role in Jiang Zhi Yin

Invigorates blood, resolves stasis, clears heat, and resolves toxins. It addresses blood stasis, a key pathological factor in hyperlipidemia. Contains resveratrol, which has recognized anti-inflammatory and lipid-lowering properties.

Yin Chen
Yin Chen

Virgate Wormwood Herb

Dosage: 10 - 15g

Temperature Slightly Cool
Taste Bitter (苦 kǔ), Acrid / Pungent (辛 xīn)
Organ Affinity Spleen, Stomach, Liver, Gallbladder
Parts Used Whole plant / Aerial parts (全草 quán cǎo)
Role in Jiang Zhi Yin

Clears damp-heat, particularly from the Liver and Gallbladder. Promotes bile secretion and supports healthy hepatic metabolism of lipids. Helps the body process and excrete turbid dampness that contributes to elevated blood fats.

Chai Hu
Chai Hu

Bupleurum root

Dosage: 6 - 10g

Temperature Slightly Cool
Taste Acrid / Pungent (辛 xīn), Bitter (苦 kǔ)
Organ Affinity Liver, Gallbladder, Lungs
Parts Used Root (根 gēn)
Role in Jiang Zhi Yin

Courses Liver Qi and relieves stagnation. Liver Qi stagnation impairs the Liver's role in governing the smooth flow of Qi and the metabolism of fats. Chai Hu ensures that Qi flows freely, supporting the overall dispersing and transforming action of the formula.

Ze Xie
Ze Xie

Water plantain rhizome

Dosage: 9 - 15g

Temperature Cold
Taste Sweet (甘 gān), Bland (淡 dàn)
Organ Affinity Kidneys, Urinary Bladder
Parts Used Tuber (块茎 kuài jīng / 块根 kuài gēn)
Role in Jiang Zhi Yin

Promotes urination and drains dampness. It leaches out turbid dampness through the urinary pathway, providing a direct route for the body to expel accumulated damp-turbidity that manifests as elevated blood lipids.

Yu Jin
Yu Jin

Turmeric tuber

Dosage: 9 - 12g

Temperature Cold
Taste Acrid / Pungent (辛 xīn), Bitter (苦 kǔ)
Organ Affinity Heart, Liver, Lungs
Parts Used Tuber (块茎 kuài jīng / 块根 kuài gēn)
Role in Jiang Zhi Yin

Invigorates blood and resolves stasis, moves Qi and resolves constraint. Yu Jin works on both the Qi and Blood levels to address the stagnation that accompanies turbid lipid accumulation. It also clears heat from the Liver and Gallbladder.

Yi Yi Ren
Yi Yi Ren

Job's Tears seed

Dosage: 10 - 20g

Temperature Cool
Taste Sweet (甘 gān), Bland (淡 dàn)
Organ Affinity Spleen, Stomach, Lungs
Parts Used Seed (种子 zhǒng zǐ / 子 zǐ / 仁 rén)
Role in Jiang Zhi Yin

Strengthens the Spleen and leaches out dampness. Addresses the root Spleen deficiency that leads to dampness and phlegm accumulation. Also supports healthy metabolism of turbid substances.

Da Huang
Da Huang

Rhubarb root and rhizome

Dosage: 3 - 6g

Temperature Cold
Taste Bitter (苦 kǔ)
Organ Affinity Spleen, Stomach, Large Intestine, Liver, Pericardium
Parts Used Root (根 gēn)
Role in Jiang Zhi Yin

Purges heat accumulation and drives out stasis. Used in small dose to promote bowel movement and expel turbid waste through the intestines, providing a downward-draining exit for accumulated lipid-related stagnation. Also invigorates blood.

Jin Ying Zi
Jin Ying Zi

Cherokee rose fruit

Dosage: 9 - 12g

Temperature Neutral
Taste Sour (酸 suān), Sweet (甘 gān), Astringent (涩 sè)
Organ Affinity Kidneys, Urinary Bladder, Large Intestine
Parts Used Fruit (果 guǒ / 果实 guǒ shí)
Role in Jiang Zhi Yin

Astringes and consolidates Kidney Essence. Serves as a restraining assistant and envoy to prevent the many draining and purging herbs (Ze Xie, Da Huang, Yin Chen) from excessively depleting the body's Essence and righteous Qi. This balancing role is critical in a formula heavily weighted toward elimination.

Modern Research (3 studies)

  • The Effects of Jiang-Zhi-Ning and Its Main Components on Cholesterol Metabolism (In vitro study, 2012)
  • Lipid-Lowering and Antioxidant Activities of Jiang-Zhi-Ning in Traditional Chinese Medicine (Preclinical study, 2011)
See all research on the formula page

Usage & Safety

How to use this formula and important safety information

Important Medical Disclaimer

The information provided here is for educational purposes only and is not intended as medical advice or to replace consultation with a qualified healthcare professional. This formula is a dietary supplement and has not been evaluated by the FDA. It is not intended to diagnose, treat, cure, or prevent any disease.

Always consult with a qualified healthcare provider, particularly if you are pregnant, nursing, have a medical condition, or are taking other medications. Discontinue use and consult your healthcare provider if you experience any adverse reactions.

Recommended Dosage

Instructions for safe storage and consumption

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Best Time to Take

30 minutes after meals, twice daily (morning and evening). Taking it after meals reduces potential gastrointestinal irritation from Da Huang and other bitter, draining herbs.

Typical Duration

Typically taken for 4 to 12 weeks as a course of treatment, then reassessed by a practitioner based on lipid levels and symptom improvement. Long-term continuous use is not recommended without periodic liver function monitoring due to the presence of He Shou Wu.

Dietary Advice

Avoid greasy, fatty, and fried foods, as these directly contribute to the Phlegm-Turbidity and food stagnation that this formula is designed to address. Reduce intake of rich meats, dairy, alcohol, and heavily processed foods. Favor light, easily digestible meals: leafy green vegetables, whole grains, mung beans, winter melon, radish, celery, seaweed, and moderate amounts of fish. These foods support the Spleen's transformative function and help resolve Dampness. Avoid excessive cold or raw foods, as these can impair the Spleen's digestive function even though the formula itself is cooling in nature. Room-temperature or warm foods are preferable. Limit sugar and refined carbohydrates, which in TCM terms generate Dampness and Phlegm. Moderate daily exercise is an important complement to the formula, as movement promotes the free flow of Qi and helps transform Phlegm-Dampness.

Modern Usage

This modern TCM formula is used for imbalanced cholesterol and stagnation of Phlegm and Blood, Qi Deficiency and food Stagnation

Special Populations

Pregnancy

Contraindicated during pregnancy. Da Huang (Rhubarb) is a strong purgative that stimulates intestinal contractions and has been classically listed as a pregnancy-prohibited herb due to its potential to induce uterine contractions. Hu Zhang (Bushy Knotweed Rhizome) and Yu Jin (Curcuma Root) both invigorate Blood circulation and move stasis, which poses a risk of threatening pregnancy. He Shou Wu, even in processed form, carries a documented risk of hepatotoxicity, and the metabolic changes of pregnancy may increase susceptibility. The overall draining and purging nature of this formula is inappropriate for pregnancy, which requires supporting and stabilizing strategies.

Breastfeeding

Use with caution during breastfeeding and only under professional supervision. Da Huang (Rhubarb) contains anthraquinone compounds that are known to pass into breast milk and may cause loose stools or diarrhea in the nursing infant. He Shou Wu (Fleeceflower Root) has documented hepatotoxicity concerns, and it is unknown to what extent its potentially harmful compounds transfer into breast milk. The formula's overall draining and purging nature may also reduce the quality or quantity of breast milk. If lipid management is needed during breastfeeding, a practitioner should consider a gentler formula without Da Huang and He Shou Wu.

Pediatric Use

This formula is generally not appropriate for children. It was designed for adult metabolic conditions (hyperlipidemia) that rarely affect pediatric populations. The formula contains Da Huang (Rhubarb), which has strong purgative effects that can easily cause diarrhea and electrolyte imbalance in children. He Shou Wu carries hepatotoxicity risks that may be more concerning in children with still-developing liver function. If a practitioner determines that a child or adolescent genuinely needs lipid management with TCM, the formula would require significant dose reduction (typically one-third to one-half of the adult dose depending on age) and close monitoring, but in practice a different, gentler approach would usually be preferred.

Drug Interactions

Anticoagulant and antiplatelet medications (e.g. warfarin, heparin, aspirin, clopidogrel): Multiple herbs in this formula invigorate Blood and transform stasis (Hu Zhang, Yu Jin, Shan Zha, Da Huang). Hu Zhang contains resveratrol, which has known antiplatelet effects. Concurrent use may increase bleeding risk. Close monitoring of INR/coagulation parameters is recommended if combined use is unavoidable.

Statin medications (e.g. atorvastatin, simvastatin, rosuvastatin): The formula targets similar cholesterol metabolism pathways (LDL receptor upregulation, HMG-CoA reductase modulation). While research on Jiang-Zhi-Ning suggests complementary mechanisms, combination use may have additive effects on liver enzyme stress. He Shou Wu's documented hepatotoxicity potential is of particular concern when combined with statins, which also carry hepatotoxic risk. Liver function monitoring is advised.

Acetaminophen (paracetamol): Research has shown that stilbene glycoside (TSG), a key component of He Shou Wu, can exacerbate acetaminophen-induced hepatotoxicity by increasing CYP2E1, CYP3A4, and CYP1A2 expression. Concurrent use should be avoided.

Antihypertensive medications: Ze Xie (Alisma) has mild diuretic effects and Jue Ming Zi (Cassia Seed) has documented blood-pressure-lowering properties. Combined use with antihypertensives may produce additive hypotensive effects.

Diabetic medications: Da Huang and Jue Ming Zi may influence blood glucose levels. Patients taking insulin or oral hypoglycemics should monitor blood sugar more closely when using this formula.

Contraindications

Avoid

Pregnancy. The formula contains Da Huang (Rhubarb), Yu Jin (Curcuma), and Hu Zhang (Bushy Knotweed), all of which promote Blood movement and may stimulate uterine contractions. Da Huang also has a strong purgative effect.

Avoid

Pre-existing liver disease or liver insufficiency. The formula contains Zhi He Shou Wu (Processed Fleeceflower Root), which has documented potential for hepatotoxicity, particularly in individuals with compromised liver function. Liver function should be monitored during use.

Caution

Spleen and Stomach deficiency-cold with chronic loose stools or diarrhea. Several herbs in this formula are cool or cold in nature (Jue Ming Zi, Ze Xie, Da Huang, Hu Zhang, Yin Chen) and will further damage already-weak digestive function. The draining and purging strategy is inappropriate for deficient constitutions.

Caution

Blood deficiency or Yin deficiency without Phlegm-Dampness. This formula emphasizes draining, moving, and purging. Using it in a depleted patient without significant Phlegm, Dampness, or stasis could consume Yin and Blood further.

Caution

Active hemorrhage or heavy menstrual bleeding. The formula contains multiple Blood-invigorating herbs (Hu Zhang, Yu Jin, Shan Zha) that could worsen bleeding.

Caution

Concurrent use with anticoagulant or antiplatelet medications without professional supervision, due to the Blood-invigorating properties of multiple ingredients.

Cautions & Warnings

Although this formula is typically safe for most individuals, it may cause side effects in some people. Pregnant women, nursing mothers, postpartum women, and those with liver disease should use the formula with caution.

As with any Chinese herbal remedy, it is advisable to seek guidance from a qualified TCM practitioner before beginning treatment.

Product Details

Manufacturing, supplier, and product specifications

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Granules

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