Formula

Zhen Gan Xi Feng Tang

Wood-Wind Suppressing Decoction | 镇肝熄风汤

Also known as:

Pacifying the Liver and Extinguishing Wind Decoction

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

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About This Formula

Traditional Chinese Medicine background and properties

Formula Description

A classical formula designed to calm the Liver and stop internally generated Wind, used for conditions related to high blood pressure, dizziness, headache, and stroke risk caused by an overactive Liver and depleted Kidney Yin. It works by anchoring rising Qi and Blood back downward, calming the Liver, nourishing Yin, and preventing the chaotic upward rush that can lead to serious neurological symptoms.

Formula Category

Main Actions

  • Sedates the Liver and extinguishes Wind
  • Subdues Yang
  • Nourishes Yin
  • Anchors and calms the Spirit
  • Directs Blood and Qi downward
  • Clears Liver Heat

TCM Patterns

In TCM, symptoms don't appear randomly — they cluster into recognizable patterns of disharmony that reveal what's out of balance in the body. Zhen Gan Xi Feng Tang is traditionally associated with these specific patterns.

The following describes this formula's classification within Traditional Chinese Medicine theory and is provided for educational purposes only.

Why Zhen Gan Xi Feng Tang addresses this pattern

When Liver and Kidney Yin are depleted over time, Yin can no longer anchor Yang, and Liver Yang rises unchecked to the upper body. This produces dizziness, headache with a sensation of heat, tinnitus, eye distension, facial flushing, and irritability. The pulse is characteristically wiry, long, and forceful. Zhen Gan Xi Feng Tang directly addresses this by using Niu Xi and Dai Zhe Shi to strongly direct the rebellious Qi and Blood back downward, while Long Gu, Mu Li, Gui Ban, and Bai Shao anchor the floating Yang and nourish the depleted Yin at its root. The Yin-nourishing herbs (Xuan Shen, Tian Dong, Gui Ban, Bai Shao) replenish the Kidney Water needed to keep Liver Wood in check, treating the underlying cause.

A practitioner would look for one or more of these signs

Dizziness

Persistent or severe dizziness and vertigo

Headaches

Headache with sensation of heat or distension in the head

Tinnitus

Ringing in the ears

Facial Flushing

Face red as if intoxicated

Irritability

Restlessness and irritability with heat sensation in the chest

Hypertension

High blood pressure with a wiry, forceful pulse

How It Addresses the Root Cause

The core disease mechanism addressed by Zhen Gan Xi Feng Tang is internal Wind generated by Liver Yang rising, rooted in Liver and Kidney Yin deficiency. In TCM theory, the Liver is a Wood-phase organ that stores Blood and governs the smooth flow of Qi. When Kidney and Liver Yin become depleted (from aging, chronic illness, emotional strain, or overwork), they can no longer anchor the Liver's Yang aspect. This unanchored Yang rises unchecked, and when it intensifies further, it transforms into internal Wind.

Zhang Xichun explains that when Liver Wood's fire blazes, the Lung's descending function fails, the Kidney's anchoring function weakens, and the Qi of the Penetrating Vessel (Chong Mai) and Stomach also rebel upward. All the organ systems' Qi moves excessively upward, carrying Blood up to the brain. The brain's blood vessels become overfilled, affecting the nervous system. In mild cases, this produces headache with a sensation of heat in the head, dizziness, eye distension, ear ringing, a flushed face, and irritability. In severe cases, the chaotic upward surging of Qi and Blood leads to sudden collapse, loss of consciousness, and what he terms "internal Wind-stroke" (equivalent to what he recognized as cerebral hemorrhage or severe hypertension).

Crucially, this is not Wind coming from outside the body. The Wind is generated internally by the body's own imbalance. Zhang Xichun specifically warns that confusing this with externally-contracted Wind and using dispersing herbs would be disastrous, as such herbs would drive more Blood upward to the brain. The underlying pattern is one of excess above (Yang and Wind surging to the head) combined with deficiency below (depleted Yin failing to anchor), with the acute excess being the dominant clinical concern.

Formula Properties

Temperature

Cool

Taste Profile

Predominantly salty and bitter with some sweet notes. The salty quality (from shells and minerals) softens hardness and anchors the Yang downward, while the bitter quality (from Xuan Shen, Chuan Lian Zi, Yin Chen) clears Heat and descends. The sweet taste of Gan Cao and Mai Ya harmonizes and protects the Stomach.

Target Organs
Liver Kidneys Stomach Lungs Brain
Channels Entered
Liver Kidney Stomach Lung Chong Mai (冲脉) Penetrating Vessel

Formula Origin

Yi Xue Zhong Zhong Can Xi Lu (医学衷中参西录, Records of Medicine with Reference to East and West) by Zhang Xichun

This is just partial information on the formula's TCM properties. More detailed information is available on the formula's dedicated page

Ingredients in Zhen Gan Xi Feng Tang

Detailed information about each herb in Zhen Gan Xi Feng Tang and their roles

Kings
Deputies
Assistants
Envoys
Chuan Niu Xi
Chuan Niu Xi

Cyathula roots

Dosage: 30g

Temperature Neutral
Taste Bitter, Sweet
Organ Affinity Kidneys, Liver
Parts Used Dried root
Role in Zhen Gan Xi Feng Tang

Used at heavy dosage to powerfully direct Blood downward, counteracting the pathological upward rush of Qi and Blood to the head. Also nourishes the Liver and Kidneys, addressing the root deficiency.

Dai Zhe Shi
Dai Zhe Shi

Hematite

Dosage: 30g

Temperature Cold
Taste Bitter
Organ Affinity Stomach, Heart, Liver, Pericardium
Parts Used The mineral
Role in Zhen Gan Xi Feng Tang

Heavy mineral that strongly directs Qi downward, sedates the Liver, anchors rising Yang, descends Stomach Qi, and pacifies rebellious Qi in the Penetrating Vessel (Chong Mai). Works with Niu Xi to urgently pull Qi and Blood downward.

Long Gu
Long Gu

Dragon bones

Dosage: 15g

Temperature Neutral
Taste Sweet
Organ Affinity Heart, Kidneys, Liver
Parts Used The fossilized bone or vertebrae
Role in Zhen Gan Xi Feng Tang

Settles and calms the spirit, anchors ascending Liver Yang, and restrains internal Wind. Its heavy, astringent nature helps contain the upward surge of Yang.

Mu Li ke
Mu Li ke

Oyster shells

Dosage: 15g

Temperature Cold
Taste Salty
Organ Affinity Urinary Bladder, Gallbladder, Kidneys, Liver
Parts Used The shell
Role in Zhen Gan Xi Feng Tang

Calms and anchors the spirit, subdues rising Yang, nourishes Yin, and softens hardness. Paired with Long Gu to powerfully subdue Liver Yang and restrain Wind.

Gui Ban
Gui Ban

Tortoise plastrons

Dosage: 15g

Temperature Cool
Taste Salty, Sweet
Organ Affinity Heart, Kidneys, Liver
Parts Used Carapace and plastron
Role in Zhen Gan Xi Feng Tang

Nourishes Yin, subdues Yang, and strengthens the Kidneys. As a shell substance, it anchors floating Yang while simultaneously enriching Kidney Yin to address the root of the condition.

Bai Shao
Bai Shao

White peony roots

Dosage: 15g

Temperature Neutral
Taste Bitter, Sour
Organ Affinity Liver, Spleen
Parts Used Dried root
Role in Zhen Gan Xi Feng Tang

Nourishes Liver Blood and Yin, softens and restrains the Liver, alleviates pain, and helps calm Liver Yang. Its sour, astringent quality counteracts the Liver's tendency to overact.

Xuan Shen
Xuan Shen

Ningpo figwort roots

Dosage: 15g

Temperature Cold
Taste Bitter
Organ Affinity Large Intestine, Liver, Stomach
Parts Used Dried rhizome
Role in Zhen Gan Xi Feng Tang

Nourishes Kidney Yin, clears deficiency Heat, and cools the Blood. Works with Tian Dong to enrich Yin at the root level, helping Kidney Water control Liver Wood.

Tian Men Dong
Tian Men Dong

Chinese asparagus tubers

Dosage: 15g

Temperature Cold
Taste Bitter, Sweet
Organ Affinity Kidneys, Lungs
Parts Used The dry tuber
Role in Zhen Gan Xi Feng Tang

Nourishes Kidney and Lung Yin, clears Lung Heat. Zhang Xichun specifically noted that when the Lung's descending function is restored, it naturally restrains the Liver. Supports the Kidney Yin foundation.

Yin Chen
Yin Chen

Virgate wormwood

Dosage: 6g

Temperature Cool
Taste Bitter, Pungent
Organ Affinity Gallbladder, Liver, Spleen, Stomach
Parts Used Dried aerial parts
Role in Zhen Gan Xi Feng Tang

Clears Liver Heat and gently soothes Liver constraint. Zhang Xichun described it as resonating with the Liver's spring-like nature, allowing the formula to subdue the Liver without suppressing its natural tendency toward free-flowing movement.

Chuan Lian Zi
Chuan Lian Zi

Sichuan chinaberries

Dosage: 6g

Temperature Cold
Taste Bitter
Organ Affinity Spleen, Liver, Small Intestine
Parts Used Dried ripe fruit
Role in Zhen Gan Xi Feng Tang

Directs Liver Qi downward and drains Liver Heat. Zhang Xichun noted it can curb the Liver's rebellious counterforce when the Liver resists being suppressed by heavy sedating herbs.

Mai Ya
Mai Ya

Malt

Dosage: 6g

Temperature Neutral
Taste Sweet
Organ Affinity Spleen, Stomach
Parts Used Dried germinated ripe fruit
Role in Zhen Gan Xi Feng Tang

Gently soothes and smooths Liver Qi, prevents the heavy sedating herbs from causing Liver Qi stagnation. As a sprouting grain, it harmonizes with the Liver's nature of growth and spreading. Also protects the Stomach from the heavy mineral ingredients.

Gan Cao
Gan Cao

Liquorice

Dosage: 4.5g

Temperature Neutral
Taste Sweet
Organ Affinity Heart, Lungs, Spleen, Stomach
Parts Used Dried root and rhizome
Role in Zhen Gan Xi Feng Tang

Harmonizes the actions of all the other herbs, protects the Stomach from damage by the heavy mineral and shell substances, and supports the Spleen's digestive function together with Mai Ya.

Modern Research (2 studies)

  • Systematic Review of RCTs: Zhen Gan Xi Feng Decoction for Essential Hypertension (2013)
  • Systematic Review and Meta-Analysis Protocol: Herbal Medicine (Zhengan Xifeng Decoction) for Essential Hypertension (2019)
See all research on the formula page

Usage & Safety

How to use this formula and important safety information

Important Medical Disclaimer

The information provided here is for educational purposes only and is not intended as medical advice or to replace consultation with a qualified healthcare professional. This formula is a dietary supplement and has not been evaluated by the FDA. It is not intended to diagnose, treat, cure, or prevent any disease.

Always consult with a qualified healthcare provider, particularly if you are pregnant, nursing, have a medical condition, or are taking other medications. Discontinue use and consult your healthcare provider if you experience any adverse reactions.

Recommended Dosage

Instructions for safe storage and consumption

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Best Time to Take

Twice daily, morning and evening, 30-60 minutes after meals (to reduce gastric irritation from the heavy mineral ingredients). Take warm.

Typical Duration

Acute crisis: 3-7 days with close monitoring. Ongoing management of hypertension or chronic Liver Yang rising: 2-8 weeks, reassessed regularly by a practitioner.

Dietary Advice

Avoid foods that aggravate Liver Yang rising: alcohol, coffee, strong tea, spicy or heavily seasoned foods, fried and greasy foods, and excessive red meat. These generate internal Heat and can provoke the upward movement of Qi and Blood that this formula aims to calm. Favor cooling, Yin-nourishing foods: celery, chrysanthemum tea, mung beans, cucumber, pears, watermelon, spinach, black sesame, and seaweed. These support the formula's cooling and descending action. Avoid emotional agitation around mealtimes and eat regular, moderate meals. Overeating burdens the Stomach and Spleen, which are already stressed by the formula's heavy mineral ingredients.

Modern Usage

Zhen Gan Xi Feng Tang is classified as a formula for Wind disorders. It is primarily used to for conditions resembling stroke. Symptoms include dizziness, a feeling of distension in the eyes, tinnitus, heat and pain in the head, a flushed face, irritability, frequent belching, gradually developing limb numbness or difficulty in movement, and deviation of the mouth and eyes.
In severe cases, it can lead to sudden dizziness and collapse, loss of consciousness, delayed recovery, or inability to fully regain normal function after waking. The pulse is typically wiry, long, and forceful.
Clinically, this formula is often used to treat hypertension, cerebral thrombosis, cerebral hemorrhage, and vascular migraines, especially in cases associated with Liver and Kidney Yin Deficiency and internal movement of Liver Wind.

Special Populations

Pregnancy

Contraindicated during pregnancy. Niu Xi (Achyranthes, used here in a heavy 30g dose) is a well-known Blood-moving herb that strongly directs Qi and Blood downward, and is classically listed among herbs contraindicated in pregnancy due to risk of inducing uterine contractions and miscarriage. Chuan Lian Zi (Melia fruit) is also considered potentially harmful in pregnancy. Additionally, Dai Zhe Shi (hematite) and the heavy mineral/shell components are not suitable for pregnant women. This formula should not be used at any stage of pregnancy.

Breastfeeding

There is limited specific data on the safety of Zhen Gan Xi Feng Tang during breastfeeding. Chuan Lian Zi (Melia fruit) contains mildly toxic meliacins that could theoretically transfer to breast milk and should be used with caution. Dai Zhe Shi (hematite) and other mineral ingredients raise concerns about trace heavy metal exposure through breast milk. Sheng Mai Ya (raw barley sprout) is traditionally used to promote the return of breast milk (hui ru), meaning it may reduce lactation. The formula's overall cold and descending nature could theoretically affect the nursing infant's digestion. Use only under close practitioner supervision while breastfeeding, and consider alternatives if possible.

Pediatric Use

This formula is not commonly used in young children, as the pattern it treats (Liver-Kidney Yin deficiency with Liver Yang rising causing stroke-like symptoms) is predominantly seen in middle-aged and older adults. However, modified versions have been used for pediatric conditions such as Tourette syndrome (childhood tic disorders), with reported efficacy in small studies. In such cases, dosages must be significantly reduced according to age and body weight (typically one-third to one-half of adult doses for school-age children). The heavy mineral and shell ingredients (Long Gu, Mu Li, Gui Ban, Dai Zhe Shi) can be hard on children's digestive systems, so Spleen-protecting herbs may need to be added. Use in children should only be under direct supervision of an experienced practitioner. Not suitable for infants or toddlers.

Drug Interactions

Antihypertensive medications: This formula has demonstrated blood pressure-lowering effects in clinical studies. When used alongside pharmaceutical antihypertensives (ACE inhibitors, ARBs, calcium channel blockers, beta-blockers, or diuretics), there is a risk of additive hypotensive effects. Blood pressure should be monitored closely and medication doses may need adjustment.

Gan Cao (Glycyrrhiza/Licorice): Licorice root can cause pseudoaldosteronism with sodium retention and potassium loss, potentially counteracting diuretics and antihypertensives. It may also interact with digoxin (by enhancing toxicity through hypokalemia), corticosteroids, and warfarin.

Anticoagulants and antiplatelet drugs: Niu Xi (Achyranthes) and Bai Shao (White Peony) have blood-moving and blood-regulating properties. When combined with warfarin, heparin, aspirin, or clopidogrel, there may be an increased risk of bleeding.

Sedatives and CNS depressants: Long Gu (Dragon Bone) and Mu Li (Oyster Shell) have calming and spirit-settling properties. Combined with benzodiazepines, barbiturates, or other sedatives, excessive sedation is theoretically possible.

Calcium supplements and calcium-containing medications: The high mineral content (Long Gu, Mu Li, Gui Ban, Dai Zhe Shi) means this formula contributes significant calcium and iron. This may affect absorption of tetracycline antibiotics, fluoroquinolones, and levothyroxine if taken simultaneously. Separate doses by at least two hours.

Contraindications

Avoid

Pregnancy. Niu Xi (Achyranthes) has blood-moving and downward-directing properties that may stimulate uterine contractions and risk miscarriage. Dai Zhe Shi and other heavy minerals are also not appropriate during pregnancy.

Avoid

Qi deficiency and Blood stasis patterns (气虚血瘀). This formula is designed for excess above with Yin deficiency below. Using it for stroke or hemiplegia caused by Qi deficiency (where Bu Yang Huan Wu Tang would be appropriate) could worsen the condition.

Caution

Spleen Yang deficiency or weak digestion. The formula contains many enriching, cloying, heavy, and sedating substances (minerals, shells, Yin-nourishing herbs) that can injure the Spleen and Stomach, causing poor appetite, loose stools, or abdominal distension.

Avoid

True Cold with false Heat patterns. If the patient's rising symptoms are due to Yang floating upward from Kidney Yang deficiency (not Liver Yang excess), this cooling and descending formula would further damage the depleted Yang.

Caution

Loose stools or diarrhea. The original text advises removing Gui Ban (turtle shell) and Dai Zhe Shi (hematite) if the bowels are loose, and adding Chi Shi Zhi instead.

Avoid

Wind-stroke caused by external Wind invasion (true Wind-stroke). Zhang Xichun explicitly warns against confusing internal Wind (from Liver Yang rising) with external Wind, as the treatment strategies are completely opposite.

Cautions & Warnings

Although this formula is typically safe for most individuals, it may cause side effects in some people. Pregnant women, nursing mothers, postpartum women, and those with liver disease should use the formula with caution.

As with any Chinese herbal remedy, it is advisable to seek guidance from a qualified TCM practitioner before beginning treatment.

Product Details

Manufacturing, supplier, and product specifications

Product Type

Granules

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