Bing Peng San

Borneol and Borax Powder · 冰硼散

Also known as: Borneolum and Borax Powder

A classical topical powder applied directly to the mouth and throat to relieve pain and promote healing of mouth ulcers, sore throats, swollen gums, and other oral inflammations caused by accumulated Heat and toxins. It works by clearing Heat, reducing swelling, and encouraging damaged tissue to heal.

Origin Wài Kē Zhèng Zōng (外科正宗, Orthodox Manual of External Medicine) by Chén Shígōng, 1617 CE — Míng dynasty, 1617 CE
Composition 4 herbs
Bing Pian
King
Bing Pian
Zhu Sha
Deputy
Zhu Sha
Peng Sha
Deputy
Peng Sha
Xu
Assistant
Xuan Ming Fen (玄明粉, Refined Mirabilite)
Explore composition

Educational content Consult qualified TCM practitioners for diagnosis and treatment

Patterns Addressed

In TCM, symptoms don't appear randomly — they cluster into recognizable patterns of disharmony that reveal what's out of balance in the body. Bing Peng San is designed to correct these specific patterns.

Why Bing Peng San addresses this pattern

Bing Peng San is designed specifically for Toxic-Heat (热毒) accumulating in the mouth, throat, and gums. When Heat-toxin lodges in the upper body, it damages the delicate mucous membranes, causing painful swelling, ulceration, and tissue decay. The formula's four ingredients all possess Heat-clearing properties. Bing Pian penetrates the inflamed tissue and directly clears Heat while relieving pain. Peng Sha and Zhu Sha resolve toxicity and prevent the tissue from further deterioration. Xuan Ming Fen draws Heat downward to prevent it from continuing to accumulate in the oral cavity. The overall effect is to clear the toxic Heat at its location, reduce swelling, relieve pain, and promote the regeneration of healthy tissue.

A practitioner would look for one or more of these signs

Sore Throat

Acute sore throat with redness and swelling

Mouth Ulcers

Painful mouth sores or canker sores

Anus Swelling

Swollen, painful, or bleeding gums

Toothache

Toothache with gum inflammation

Tonsil Swelling

Swollen or stiff tongue

Commonly Prescribed For

These conditions can arise from the patterns above. A practitioner would consider Bing Peng San when these conditions are specifically caused by those patterns — not for all cases of these conditions.

Arises from: Toxic-Heat

TCM Interpretation

In TCM, mouth ulcers (口疮, kou chuang) are closely related to the Heart and Spleen. The mouth is the opening of the Spleen, and the tongue is considered the 'sprout' of the Heart. When excessive Heat accumulates in these organ systems, whether from dietary excess (spicy or rich foods, alcohol), emotional stress generating internal fire, or overwork depleting Yin and allowing deficiency-Heat to rise, it flares upward to the oral cavity. There, the Heat scorches the delicate mucous membrane, causing localized tissue damage that presents as painful, round or oval ulcers with red borders. The key distinction is whether the Heat is of an excess type (from overeating or acute infection) or a deficiency type (from chronic Yin depletion). Bing Peng San is appropriate for the excess-Heat presentation.

Why Bing Peng San Helps

Bing Peng San is applied directly to the ulcer, allowing its ingredients to act immediately at the site of tissue damage. Bing Pian (Borneol) penetrates the ulcer surface to clear local Heat and provide rapid pain relief. Peng Sha (Borax) and Zhu Sha (Cinnabar) resolve the toxic accumulation that is preventing healing, and their anti-putrefactive properties help protect the damaged tissue from further decay. Xuan Ming Fen (Mirabilite) softens any hardened or raised tissue around the ulcer and draws residual Heat away. Modern pharmacological research has confirmed anti-inflammatory, antimicrobial, and analgesic effects, supporting its traditional use for accelerating ulcer healing and reducing pain.

Also commonly used for

Tonsillitis

Acute tonsillitis

Periodontitis

Periodontal disease

Oral Thrush

Oral candidiasis (thrush)

Lumps

Epidemic parotitis (mumps)

Otitis Media

Acute and chronic middle ear infections

Herpes Zoster Infection

Shingles (topical application)

Vaginitis

Candidal vaginitis (topical use)

What This Formula Does

Every TCM formula has a specific set of actions — here's what Bing Peng San does in the body, explained in both everyday and TCM terms

Therapeutic focus

In practical terms, Bing Peng San is primarily used to support these areas of health:

TCM Actions

In TCM terminology, these are the specific therapeutic actions that Bing Peng San performs to restore balance in the body:

How It Addresses the Root Cause

TCM doesn't just suppress symptoms — it aims to resolve the underlying imbalance. Here's how Bing Peng San works at the root level.

Bing Peng San addresses conditions where Heat-Toxin (热毒, rè dú) accumulates in the upper body, concentrating in the mouth, throat, gums, and tongue. In TCM understanding, the mouth and throat are places where several channels converge, particularly the Lung and Stomach channels. When Heat enters these channels, whether from external pathogenic invasion, dietary excess (spicy or greasy foods, alcohol), emotional stress generating internal Fire, or Phlegm-Fire smoldering in the chest, the result is that Heat-Toxin flares upward and lodges in the oral and pharyngeal tissues.

This Heat-Toxin scorches the local flesh and obstructs the flow of Qi and Blood in the affected area. The stagnation produces swelling, redness, and pain. Where the tissue is burned through, ulceration and erosion appear, as seen in mouth sores (口疮), gum inflammation, and throat abscesses. The white or yellowish coating on ulcers represents turbid Toxin accumulation. Pain can be severe because the throat and mouth are sensitive areas rich in channels, and the Heat creates intense local congestion.

As a topical powder applied directly to the affected site, Bing Peng San works by delivering cold, toxin-clearing mineral substances right to the point of disease. Rather than treating the systemic root cause through internal medicine, it provides direct, local relief by cooling the inflamed tissue, resolving the toxic accumulation, and reducing the swelling that obstructs normal function. For this reason, it is often used alongside internal formulas that address the underlying pattern generating the Heat.

Formula Properties

Every formula has an inherent temperature, taste, and affinity for specific organs — these properties determine how it interacts with the body

Overall Temperature

Cold

Taste Profile

Predominantly salty and acrid (pungent), with a cooling aromatic quality. The salty taste from Borax and Mirabilite softens hardness and clears Heat, while the acrid, aromatic Borneol penetrates and opens, relieving pain.

Channels Entered

Ingredients

4 herbs

The herbs that make up Bing Peng San, organized by their role in the prescription

King — Main ingredient driving the formula
Deputy — Assists and enhances the King
Assistant — Supports or moderates other herbs
King — Main ingredient driving the formula
Bing Pian

Bing Pian

Borneol

Dosage 1.5g
Temperature Cool
Taste Acrid / Pungent (辛 xīn), Bitter (苦 kǔ)
Organ Affinity Heart, Spleen, Lungs

Role in Bing Peng San

The chief medicinal in this formula. Bing Pian is acrid and bitter, slightly cold in nature, and enters the Heart channel. It clears Heat, relieves pain, reduces swelling, and dispels putrefaction. Its aromatic nature allows it to penetrate tissue and open the local pathways, directly addressing the pain and inflammation in the mouth and throat.
Deputies — Assists and enhances the King
Zhu Sha

Zhu Sha

Cinnabar

Dosage 1.8g
Temperature Cool
Taste Sweet (甘 gān)
Organ Affinity Heart
Preparation Water-levigated (水飞) into an extremely fine powder to reduce toxicity and ensure safe topical application

Role in Bing Peng San

Sweet and cold, Zhu Sha clears Heart Heat and resolves toxins. It supports Bing Pian in clearing Heat-toxin from the mouth and throat, and has an additional calming effect that helps settle inflammation. It also assists in unblocking the local vessels to promote healing.
Peng Sha

Peng Sha

Borax

Dosage 15g
Temperature Cool
Taste Sweet (甘 gān), Salty (咸 xián)
Organ Affinity Lungs, Stomach
Preparation Calcined (煅) before grinding into powder

Role in Bing Peng San

Sweet, salty, and cool in nature, Peng Sha clears Heat, resolves toxins, reduces swelling, and prevents putrefaction. A key throat and oral medicinal, it works alongside Bing Pian to clear toxic accumulation and promote tissue regeneration in the oral cavity.
Assistant — Supports or moderates other herbs
Xu

Xuan Ming Fen (玄明粉, Refined Mirabilite)

Dosage 15g

Role in Bing Peng San

Salty and cold, Xuan Ming Fen softens hardness and clears Heat. It guides Heat downward and out of the body, reinforcing the Heat-clearing power of the King and Deputy herbs. It also helps soften swollen, hardened tissue in the throat and mouth.

Why This Combination Works

How the herbs in Bing Peng San complement each other

Overall strategy

Bing Peng San addresses acute Heat-toxin accumulation in the mouth, throat, and gums. The formula uses a combination of aromatic, Heat-clearing, and toxin-resolving medicinals applied directly to the affected site to clear the Heat, reduce swelling and pain, dispel decayed tissue, and promote healing.

King herb

Bing Pian (Borneol) serves as the King because its aromatic, penetrating nature allows it to reach deeply into the local tissue. Being slightly cold and entering the Heart channel, it directly clears Heat and relieves the burning pain characteristic of toxic oral inflammation. Its ability to open local tissue pathways ensures that the other ingredients can also exert their effects at the site of disease.

Deputy herbs

Zhu Sha (Cinnabar) reinforces the King's Heat-clearing action by clearing Heart Heat and resolving toxins, and it also helps unblock local blood vessels to reduce congestion in inflamed tissue. Peng Sha (Borax) is a classical throat medicinal that clears Heat-toxin, prevents putrefaction, and reduces swelling. Together, the two Deputies greatly amplify the formula's ability to detoxify and heal the affected mucous membranes.

Assistant herbs

Xuan Ming Fen (Refined Mirabilite) acts as a reinforcing assistant. Its salty, cold nature softens hardness, clears Heat, and guides accumulated Heat downward and away from the upper body. This prevents the Heat-toxin from lingering and supports the King and Deputies in their clearing action.

Notable synergies

The pairing of Bing Pian and Peng Sha is the formula's signature combination: Bing Pian opens the tissue and clears Heat with its aromatic penetration, while Peng Sha provides sustained anti-toxic and anti-putrefactive action. Together they address both the acute pain and the underlying toxic accumulation. The addition of Xuan Ming Fen introduces a downward-directing force that prevents Heat from continuing to flare upward toward the head and throat.

How to Prepare

Traditional preparation instructions for Bing Peng San

Grind Zhu Sha (Cinnabar) by water-levigation (水飞) into an extremely fine powder. Crush Peng Sha (Borax, calcined) into a fine powder. Grind Bing Pian (Borneol) finely. Combine all powders with Xuan Ming Fen (Mirabilite), sieve and mix thoroughly until uniformly blended. The resulting powder should be pinkish in color with an aromatic fragrance and a pungent, cooling taste.

To use, blow or gently apply a small amount of the powder directly onto the affected area of the mouth, throat, or gums using a thin tube or cotton swab. Apply several times daily. In severe cases, apply five to six times per day. Store in a tightly sealed container in a cool, dry place.

Common Modifications

How practitioners adapt Bing Peng San for specific situations

Added
Er Cha

Er Cha (Catechu), small amount, to promote tissue regeneration and stop pain

Zhen Zhu

Zhen Zhu (Pearl), small amount, to promote healing of ulcerated surfaces and resolve toxins

Er Cha and Zhen Zhu both promote the regeneration of damaged mucous membrane tissue. Adding them strengthens the formula's ability to heal open sores and relieve the pain of exposed ulcer surfaces.

Educational content — always consult a qualified healthcare provider or TCM practitioner before using any herbal formula.

Contraindications

Situations where Bing Peng San should not be used or requires extra caution

Avoid

Ulcers or sores caused by deficiency-Cold patterns (虚寒性溃疡). This formula is strongly cooling and toxin-clearing, and is only appropriate for Heat-Toxin conditions. Applying it to Cold-type sores will worsen the condition.

Avoid

Persons with known allergy or hypersensitivity to any of the formula's mineral ingredients (Borneol, Borax, Cinnabar, or Mirabilite). Discontinue immediately if local irritation, burning, or allergic reaction develops.

Avoid

Liver or kidney impairment. Zhu Sha (Cinnabar) contains mercuric sulfide. Although topical absorption is minimal, individuals with compromised hepatic or renal function are at greater risk of mercury accumulation and toxicity.

Caution

Prolonged or excessive use. This formula contains mineral substances (Cinnabar, Borax) that should not be applied continuously over long periods. Use should be limited to the acute phase of the condition.

Caution

Large open wounds or extensively eroded mucosal surfaces. Applying to very large areas of damaged tissue increases potential systemic absorption of Cinnabar (mercury) and Borax (boron).

Caution

Concurrent use with iodide or bromide medications. Cinnabar can react with iodides and bromides to form toxic mercury iodide or mercury bromide compounds.

Special Populations

Important considerations for pregnancy, breastfeeding, and pediatric use

Pregnancy

Use with caution during pregnancy. Bing Pian (Borneol) is traditionally contraindicated in pregnancy due to its strongly penetrating aromatic nature. Zhu Sha (Cinnabar) contains mercuric sulfide, and animal studies have shown that prolonged cinnabar exposure prior to and during gestation can cause embryonic malformations, though short-term exposure during mid-to-late pregnancy at standard doses showed no obvious embryotoxicity. Since Bing Peng San is a topical formula applied in small amounts to oral or throat mucosa, systemic absorption is minimal. Nevertheless, given the presence of both Borneol and Cinnabar, pregnant women should only use this formula under professional guidance and for the shortest duration necessary. Avoid use in the first trimester.

Breastfeeding

The Chinese Pharmacopoeia notes that breastfeeding women should not use Bing Peng San (哺乳期妇女不宜使用). Although it is a topical formula and systemic absorption from small oral or throat applications is low, the presence of Zhu Sha (Cinnabar, containing mercuric sulfide) raises concern about even trace amounts of mercury transferring to breast milk. Borax (Peng Sha) is also a potential concern as boron compounds can be absorbed through mucous membranes. If use is absolutely necessary during breastfeeding, it should be limited to minimal amounts for the shortest possible duration, and the mother should avoid breastfeeding immediately after application. Consult a healthcare provider before use.

Children

The Chinese Pharmacopoeia specifies that neonates (newborns) should use Bing Peng San with caution (新生儿慎用). Children's organs are considered delicate and immature, making them more susceptible to potential mercury toxicity from Zhu Sha (Cinnabar). Classical sources such as the Yao Lian Qi Mi do mention using this formula for pediatric conditions like goose-mouth sores (thrush), but modern guidance recommends caution. For older children, only very small amounts should be applied, and treatment duration should be kept as short as possible. Parents should not self-administer this formula to young children without professional guidance. The amount applied should be proportionally reduced for children, and the frequency of application should be less than for adults.

Drug Interactions

If you are taking pharmaceutical medications, be aware of these potential interactions with Bing Peng San

Iodide and bromide medications: Zhu Sha (Cinnabar, mercuric sulfide) in this formula can react with iodide or bromide compounds to form highly toxic mercury iodide or mercury bromide. Avoid concurrent use with potassium iodide, sodium bromide, or bromide-containing sedatives. Also avoid consuming iodized salt or kelp/seaweed in excess during use.

Medications containing aluminum: Cinnabar can react with aluminum-containing compounds, potentially increasing toxicity. Avoid concurrent use with aluminum hydroxide antacids or sucralfate if there is any possibility of co-ingestion.

Theophylline and propranolol (and other methyl-group containing drugs): Research suggests that cinnabar may interact with drugs containing methyl structures to form methylmercury, which is far more toxic than the original mercuric sulfide. Caution is warranted for patients taking these medications.

General note: Since Bing Peng San is a topical formula applied in small amounts, systemic drug interactions are unlikely at normal use levels. However, because it is applied to mucous membranes where absorption does occur, these precautions remain clinically relevant, especially with repeated or prolonged use.

Usage Guidance

Practical advice for getting the most out of Bing Peng San

Best time to take

Apply (blow or dab) directly to the affected area several times throughout the day as needed, especially after meals and before bed. Rinse the mouth gently before application to ensure good contact with the tissue.

Typical duration

Acute use: 3-7 days, applied several times daily until symptoms resolve. Not suitable for prolonged continuous use.

Dietary advice

Avoid smoking, alcohol, and spicy, pungent, or greasy foods during use, as these generate Heat and can aggravate oral and throat inflammation. The classical text Quan Guo Zhong Yao Cheng Yao Chu Fang Ji specifically advises against spicy foods, meat, and wheat-flour products (忌食辛辣、荤、面等物). Cool, bland, soft foods are preferable to avoid irritating inflamed oral or throat tissues. Drink adequate fluids to keep the mouth and throat moist.

Bing Peng San originates from Wài Kē Zhèng Zōng (外科正宗, Orthodox Manual of External Medicine) by Chén Shígōng, 1617 CE Míng dynasty, 1617 CE

Classical Texts

Key passages from the classical Chinese medical texts that first described Bing Peng San and its clinical use

《外科正宗》 (Wài Kē Zhèng Zōng, Orthodox Manual of External Medicine):

Original indication: 「咽喉口齿新久肿痛,及久嗽痰火咽哑作痛。」
Translation: "For new or chronic swelling and pain of the throat, mouth, and teeth, as well as chronic cough with Phlegm-Fire causing hoarseness and sore throat."

《外科大成》 (Wài Kē Dà Chéng, Grand Compendium of External Medicine):

Extended indication: 「舌胀痰包,重舌、木舌。」
Translation: "For tongue swelling with Phlegm accumulation, double tongue, and wooden tongue [tongue stiffness]."

《医宗金鉴》 (Yī Zōng Jīn Jiàn, Golden Mirror of Medical Tradition):

Further indication: 「口疮,白点满口。」
Translation: "For mouth sores, with white spots filling the mouth."

方歌 (Formula Song):

「冰硼散中加朱砂,更添玄明效堪夸,清热解毒消肿痛,咽肿齿痛口疮佳。」
Translation: "Bing Peng San adds Cinnabar within, plus Xuan Ming Fen its praise to win; clearing Heat-Toxin, easing swelling and pain, for sore throat, toothache, and mouth sores, it's excellent to gain."

Historical Context

How Bing Peng San evolved over the centuries — its origins, lineage, and place in the broader tradition of Chinese medicine

Bing Peng San was first recorded in the Wài Kē Zhèng Zōng (《外科正宗》, Orthodox Manual of External Medicine), written by the renowned Ming Dynasty surgeon Chén Shí Gōng (陈实功, 1555-1636) and published in 1617. Chen was the leading figure of the "Orthodox School" (正宗派) of Chinese external medicine, and his text systematically compiled over 120 surgical and dermatological conditions with detailed treatments. The Sì Kù Quán Shū (四库全书) editors praised the work as having "the most detailed case descriptions and the most refined treatment methods" (列证最详,论治最精).

Bing Peng San exemplifies Chen's philosophy of combining topical external treatment with internal medicine. As a simple four-ingredient powder blown or dabbed onto affected tissues, it became one of the most widely used throat and mouth formulas in Chinese medicine. Later texts expanded its indications: the Wài Kē Dà Chéng (外科大成) added tongue conditions, the Yī Zōng Jīn Jiàn (医宗金鉴) included widespread oral thrush, and the Yào Lián Qǐ Mì (药奁启秘) specified its use for pediatric goose-mouth sores (鹅口疮, neonatal oral candidiasis) and tonsillitis. In modern times, it has been included in the Chinese Pharmacopoeia and the National Medical Insurance formulary, and clinical practitioners have extended its use to conditions such as mumps, middle ear infections, herpes zoster, and cervical erosion, applied topically in various preparations.