Formula

Zuo Gu Shen Jing Tong Wan

坐骨神经痛丸

Also known as:

Zuo Gu Shen Jing Tong Wan , Zuo Gu Shen Jing Tong Pian , Sciaticlear , Sciatica Pills , Qiang Li Zuo Gu Shen Jing Tong Wan

Properties

Wind-Damp dispelling formulas · Warm

Key Ingredients

Ru Xiang, Mo Yao

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

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About This Formula

Traditional Chinese Medicine background and properties

Formula Description

A modern Chinese formula designed to relieve sciatic nerve pain, lower back pain, and joint stiffness in the lower body. It works by clearing blockages in the channels, improving blood circulation, reducing inflammation and pain, and strengthening the kidneys and bones. It is most commonly used for pain that radiates from the lower back through the hip and down the leg.

Formula Category

Main Actions

  • Invigorates Blood and Dispels Stasis
  • Unblocks the Channels and Alleviates Pain
  • Dispels Wind-Dampness
  • Softens and Relaxes the Sinews
  • Benefits the Kidneys and Strengthens the Bones
  • Nourishes Blood

TCM Patterns

In TCM, symptoms don't appear randomly — they cluster into recognizable patterns of disharmony that reveal what's out of balance in the body. Zuo Gu Shen Jing Tong Wan is traditionally associated with these specific patterns.

The following describes this formula's classification within Traditional Chinese Medicine theory and is provided for educational purposes only.

Why Zuo Gu Shen Jing Tong Wan addresses this pattern

This formula directly treats Wind-Cold-Damp Bi syndrome affecting the lower back and legs. The pathogenic factors of Wind, Cold, and Dampness invade the channels and collaterals, causing obstruction that manifests as pain, heaviness, numbness, and stiffness. Xi Xian Cao, Wei Ling Xian, and Shen Jin Cao dispel Wind-Dampness and open the channels. Ru Xiang and Mo Yao break through the Blood stasis that accumulates secondary to prolonged channel obstruction. Ba Ji Tian warms the Kidney Yang to expel Cold from the lower body. The formula's combined actions clear the pathogenic factors while restoring Qi and Blood flow through the affected areas.

A practitioner would look for one or more of these signs

Sciatica

Pain radiating from the lower back down through the buttock and leg

Lower Back Pain

Dull, heavy aching in the lower back that worsens with cold or damp weather

Skin Numbness

Numbness or tingling in the hip, thigh, or leg

Muscle Weakness

Weakness in the lower limbs with difficulty walking

Joint Stiffness

Stiffness in the lower back, hip, or knee joints

How It Addresses the Root Cause

Sciatica and lower body pain addressed by this formula arise from a combination of external pathogenic factors and internal deficiency. Wind, Cold, and Dampness invade the lower back and legs, lodging in the channels and collaterals (especially the Bladder and Gallbladder channels that traverse the buttocks, posterior and lateral thighs, and legs). These pathogens obstruct the free flow of Qi and Blood through the channels, and the classical principle "where there is obstruction, there is pain" (不通则痛) applies directly.

Over time, or in patients with pre-existing weakness, the Kidneys and Liver become depleted. Since the Kidneys govern the bones and the lower back, and the Liver governs the sinews, their insufficiency means the lumbar region and lower extremities lack nourishment. The sinews become stiff, the bones become fragile, and the channels become more vulnerable to pathogenic invasion. Blood stasis then develops as a secondary consequence of prolonged channel obstruction and deficiency, creating a vicious cycle where stagnant Blood further blocks the channels and worsens pain, numbness, and weakness.

The formula addresses this by simultaneously removing the obstructions (dispelling Wind-Dampness, invigorating Blood, opening the channels) while supporting the root deficiency (tonifying the Kidneys, nourishing Blood, strengthening the sinews and bones). This dual approach of treating both the root and the branch is essential for conditions that are both excess (obstruction) and deficient (Kidney-Liver weakness).

Formula Properties

Temperature

Warm

Taste Profile

Predominantly acrid and bitter with underlying sweetness. The acrid taste opens the channels and moves Blood, the bitter taste drains and clears obstruction, and the sweet taste supports and tonifies the Kidneys and Blood.

Target Organs
Kidneys Liver Urinary Bladder
Channels Entered
Liver Kidney Bladder Gallbladder

Formula Origin

Modern Chinese empirical formula (contemporary clinical formulation)

This is just partial information on the formula's TCM properties. More detailed information is available on the formula's dedicated page

Ingredients in Zuo Gu Shen Jing Tong Wan

Detailed information about each herb in Zuo Gu Shen Jing Tong Wan and their roles

Ru Xiang
Ru Xiang

Frankincense resin

Dosage: 3 - 6g

Temperature Warm
Taste Acrid / Pungent (辛 xīn), Bitter (苦 kǔ)
Organ Affinity Heart, Liver, Spleen
Parts Used Resin / Sap (树脂 shù zhī / 汁 zhī)
Role in Zuo Gu Shen Jing Tong Wan

Powerfully invigorates Blood, dispels stasis, and alleviates pain. As one of the two King herbs, it directly addresses Blood stagnation in the channels and collaterals of the lower body, providing strong analgesic action for sciatic nerve pain.

Mo Yao
Mo Yao

Myrrh

Dosage: 3 - 6g

Temperature Neutral
Taste Bitter (苦 kǔ), Acrid / Pungent (辛 xīn)
Organ Affinity Heart, Liver, Spleen
Parts Used Resin / Sap (树脂 shù zhī / 汁 zhī)
Role in Zuo Gu Shen Jing Tong Wan

Paired with Ru Xiang, it strongly invigorates Blood and disperses stasis while reducing swelling and generating flesh. Together with Ru Xiang, this classical pairing is the core of the formula's pain-relieving action.

Ji Xue Teng
Ji Xue Teng

Spatholobus stem

Dosage: 9 - 15g

Temperature Warm
Taste Bitter (苦 kǔ), Sweet (甘 gān)
Organ Affinity Heart, Liver, Kidneys
Parts Used Stem (茎 jīng)
Role in Zuo Gu Shen Jing Tong Wan

Invigorates and tonifies Blood while relaxing the sinews and unblocking the channels. It bridges the formula's Blood-moving and channel-opening functions, ensuring that the lower body receives adequate nourishment while stasis is cleared.

Yan Hu Suo
Yan Hu Suo

Corydalis tuber

Dosage: 6 - 12g

Temperature Warm
Taste Acrid / Pungent (辛 xīn), Bitter (苦 kǔ)
Organ Affinity Heart, Liver, Spleen
Parts Used Tuber (块茎 kuài jīng / 块根 kuài gēn)
Role in Zuo Gu Shen Jing Tong Wan

One of the strongest pain-relieving herbs in the Chinese pharmacopoeia. It activates Qi and Blood circulation, enhancing the analgesic effect of the King herbs, with particular strength for pain in the chest, abdomen, and limbs.

Chuan Xiong
Chuan Xiong

Szechuan lovage rhizome

Dosage: 6 - 9g

Temperature Warm
Taste Acrid / Pungent (辛 xīn)
Organ Affinity Liver, Gallbladder, Pericardium
Parts Used Rhizome (根茎 gēn jīng)
Role in Zuo Gu Shen Jing Tong Wan

Invigorates Blood and promotes Qi movement. Known as the 'Qi herb within Blood herbs,' it ensures Qi circulates to move Blood effectively, helping the formula's analgesic herbs reach the channels of the lower body.

Jiang Huang
Jiang Huang

Turmeric rhizome

Dosage: 6 - 9g

Temperature Warm
Taste Acrid / Pungent (辛 xīn), Bitter (苦 kǔ)
Organ Affinity Spleen, Liver
Parts Used Rhizome (根茎 gēn jīng)
Role in Zuo Gu Shen Jing Tong Wan

Invigorates Blood and opens the channel pathways. It has a particular affinity for the limbs and shoulders, helping to guide the Blood-moving action of the formula into the extremities and relieve obstruction in the channels.

Xi Xian Cao
Xi Xian Cao

Siegesbeckia herb

Dosage: 9 - 15g

Temperature Cold
Taste Bitter (苦 kǔ), Acrid / Pungent (辛 xīn)
Organ Affinity Liver, Kidneys
Parts Used Whole plant / Aerial parts (全草 quán cǎo)
Role in Zuo Gu Shen Jing Tong Wan

Dispels Wind-Dampness, unblocks channels, and relaxes the sinews. It addresses the Wind-Damp component of Bi syndrome, working synergistically with Wei Ling Xian to clear pathogenic factors from the lower body joints and channels.

Wei Ling Xian
Wei Ling Xian

Clematis root

Dosage: 6 - 9g

Temperature Warm
Taste Acrid / Pungent (辛 xīn), Salty (咸 xián)
Organ Affinity Urinary Bladder
Parts Used Root (根 gēn)
Role in Zuo Gu Shen Jing Tong Wan

Strongly dispels Wind-Dampness and unblocks the channels. It has a penetrating quality that helps clear obstructions throughout all the channels, particularly useful for pain and numbness that radiates along a pathway.

Shen Jin Cao
Shen Jin Cao

Common clubmoss

Dosage: 9 - 15g

Temperature Warm
Taste Bitter (苦 kǔ), Acrid / Pungent (辛 xīn)
Organ Affinity Liver, Spleen, Kidneys
Parts Used Whole plant / Aerial parts (全草 quán cǎo)
Role in Zuo Gu Shen Jing Tong Wan

Dispels Wind-Dampness, relaxes the sinews and tendons, and opens the channels. It complements the channel-opening herbs while specifically addressing tendon and sinew stiffness and contraction in the lower limbs.

Ba Ji Tian
Ba Ji Tian

Morinda root

Dosage: 6 - 9g

Temperature Slightly Warm
Taste Acrid / Pungent (辛 xīn), Sweet (甘 gān)
Organ Affinity Kidneys, Liver
Parts Used Root (根 gēn)
Role in Zuo Gu Shen Jing Tong Wan

Tonifies Kidney Yang, strengthens the sinews and bones, and expels Wind-Dampness. It addresses the root deficiency that often underlies chronic lower back and leg pain, supporting the body's structural resilience.

Shu Di Huang
Shu Di Huang

Prepared Rehmannia root

Dosage: 9 - 15g

Temperature Slightly Warm
Taste Sweet (甘 gān)
Organ Affinity Liver, Kidneys
Parts Used Tuber (块茎 kuài jīng / 块根 kuài gēn)
Role in Zuo Gu Shen Jing Tong Wan

Nourishes Blood and tonifies Kidney Yin. It provides the nourishing foundation to prevent the formula's many Blood-moving and channel-scouring herbs from depleting vital substances, and it supports the Kidneys which govern the bones and lower back.

Usage & Safety

How to use this formula and important safety information

Important Medical Disclaimer

The information provided here is for educational purposes only and is not intended as medical advice or to replace consultation with a qualified healthcare professional. This formula is a dietary supplement and has not been evaluated by the FDA. It is not intended to diagnose, treat, cure, or prevent any disease.

Always consult with a qualified healthcare provider, particularly if you are pregnant, nursing, have a medical condition, or are taking other medications. Discontinue use and consult your healthcare provider if you experience any adverse reactions.

Recommended Dosage

Instructions for safe storage and consumption

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Best Time to Take

After meals, 2-3 times daily, to reduce potential stomach irritation from Ru Xiang and Mo Yao.

Typical Duration

Typically taken for 2-8 weeks depending on severity; chronic cases may require longer courses with periodic reassessment by a practitioner.

Dietary Advice

Avoid cold and raw foods (salads, iced drinks, raw fish) while taking this formula, as Cold constricts the channels and can counteract the formula's warming, channel-opening effects. Limit greasy, heavy, and deep-fried foods that generate Dampness and impede the flow of Qi and Blood. Foods that support the formula's actions include warming proteins (lamb, chicken), bone broths, ginger, turmeric, and foods that nourish Blood such as dark leafy greens and black beans. Avoid excessive alcohol consumption, although small amounts of warm rice wine can sometimes enhance the formula's Blood-moving effect if recommended by a practitioner.

Special Populations

Pregnancy

Contraindicated during pregnancy. This formula contains several herbs with strong Blood-invigorating and channel-opening properties that pose risks during pregnancy: - Ru Xiang (Frankincense) and Mo Yao (Myrrh): actively move Blood and may stimulate uterine contractions. - Yan Hu Suo (Corydalis): strongly promotes Qi and Blood movement. - Chuan Xiong (Szechuan Lovage): a powerful Blood-activating herb that moves Qi upward and outward. - Jiang Huang (Turmeric): breaks Blood stasis and may affect uterine tone. The cumulative effect of these herbs creates a significant risk of miscarriage or premature labor. This formula should not be used at any stage of pregnancy.

Breastfeeding

Use with caution during breastfeeding. While this formula does not contain known galactagogue-inhibiting herbs, several ingredients raise concerns: - Ru Xiang (Frankincense) and Mo Yao (Myrrh) contain volatile oils and resins that may transfer into breast milk; their safety profile during lactation has not been established. - Yan Hu Suo (Corydalis) contains alkaloids (including tetrahydropalmatine) with sedative and analgesic properties that could potentially affect the nursing infant. - Ba Ji Tian (Morinda root) has hormonal-modulating effects whose impact on breast milk composition is unknown. If use is considered necessary, consult a qualified practitioner and monitor the infant for any unusual drowsiness, digestive upset, or changes in feeding behavior.

Pediatric Use

This formula is generally not recommended for young children (under 12). It was designed for adult musculoskeletal pain conditions like sciatica, which are uncommon in pediatric populations. The strong Blood-invigorating herbs (Ru Xiang, Mo Yao, Yan Hu Suo) are potent and may be too harsh for a child's developing system. For adolescents (12-18) with relevant conditions, dosage should be reduced to approximately one-half to two-thirds of the adult dose, and treatment should be supervised by a qualified practitioner. Duration of use should be kept as short as clinically necessary.

Drug Interactions

Anticoagulant and antiplatelet medications (warfarin, heparin, aspirin, clopidogrel): This formula contains multiple Blood-invigorating herbs (Ru Xiang, Mo Yao, Chuan Xiong, Yan Hu Suo, Jiang Huang, Ji Xue Teng) that may have additive anticoagulant effects, increasing the risk of bleeding. Concurrent use should be avoided or closely monitored with regular coagulation testing.

Sedatives and CNS depressants (benzodiazepines, opioid analgesics, sleep medications): Yan Hu Suo (Corydalis) contains tetrahydropalmatine, which has documented sedative and analgesic properties. Concurrent use may potentiate sedation.

Antidiabetic medications: Some herbs in this formula may have mild blood-glucose-lowering effects. Patients on insulin or oral hypoglycemics should monitor blood sugar levels more closely.

NSAIDs (ibuprofen, naproxen): While the formula is sometimes used alongside conventional pain management, combining Blood-moving herbs with NSAIDs may increase the risk of gastrointestinal bleeding.

Contraindications

Avoid

Pregnancy. The formula contains multiple Blood-invigorating herbs (Ru Xiang, Mo Yao, Chuan Xiong, Yan Hu Suo, Jiang Huang) that may stimulate uterine contractions.

Avoid

Active bleeding disorders or patients on anticoagulant therapy. The formula's strong Blood-activating properties may worsen bleeding or potentiate anticoagulant effects.

Caution

Heat-type Bi Syndrome with prominent redness, swelling, and heat in the joints. This formula is best suited for Cold-Damp type obstruction and may not adequately address Heat patterns.

Caution

Yin deficiency with significant internal Heat. The warming and Blood-moving nature of this formula may aggravate Yin-deficient Heat signs such as night sweats, hot flashes, and a dry red tongue.

Caution

Weak digestion or Spleen-Stomach deficiency. Herbs like Shu Di Huang and Ru Xiang can be heavy on the Stomach. Nausea or poor appetite may occur; dose reduction or adding digestive herbs may be necessary.

Cautions & Warnings

is typically safe for most individuals, but it can lead to side effects in some cases. Pregnant, nursing, or postpartum women, as well as those with liver conditions, should use this formula cautiously and preferably under professional supervision.

As with any Chinese herbal remedy, it is advisable to seek guidance from a qualified Traditional Chinese Medicine (TCM) practitioner before beginning treatment with Liu Wei Di Huang Wan.

Product Details

Manufacturing, supplier, and product specifications

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Granules

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Treasure of the East

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