Formula

Yu Ye Tang

玉液汤

Properties

Dryness-treating formulas · Slightly Cool

Key Ingredients

Shan Yao, Huang Qi

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

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About This Formula

Traditional Chinese Medicine background and properties

Formula Description

A classical formula designed to relieve persistent thirst, frequent urination, and fatigue caused by a combined deficiency of Qi and Yin. It works by strengthening the Spleen to raise vital fluids upward to moisten the Lungs, while nourishing Yin and securing the Kidneys. It is one of the most commonly used traditional formulas for managing symptoms associated with diabetes.

Formula Category

Main Actions

  • Tonifies Qi and generates fluids
  • Nourishes Yin and Moistens Dryness
  • Raises Clear Yang
  • Clears Deficiency Heat
  • Secures Essence and Stops Enuresis

TCM Patterns

In TCM, symptoms don't appear randomly — they cluster into recognizable patterns of disharmony that reveal what's out of balance in the body. Yu Ye Tang is traditionally associated with these specific patterns.

The following describes this formula's classification within Traditional Chinese Medicine theory and is provided for educational purposes only.

Why Yu Ye Tang addresses this pattern

Yu Ye Tang is the representative formula for Qi and Yin deficiency manifesting as wasting-thirst (xiao ke). When Spleen Qi is too weak to raise clear fluids upward, and Yin is too depleted to moisten the Lungs and Stomach, a vicious cycle develops: the body cannot distribute fluids, thirst intensifies, excessive drinking leads to excessive urination, and the Kidneys cannot retain what little fluid remains. The formula breaks this cycle from multiple angles. Shan Yao and Huang Qi restore the Spleen's Qi to raise fluids upward. Zhi Mu and Tian Hua Fen replenish the depleted Yin and clear the secondary dryness-Heat. Ji Nei Jin helps the Spleen transform nutrients properly rather than losing them in the urine. Wu Wei Zi astringes the Kidneys to retain fluids. The formula thus simultaneously tonifies both Qi and Yin while restoring proper fluid circulation.

A practitioner would look for one or more of these signs

Thirst

Persistent thirst not relieved by drinking water

Frequent Urination

Frequent and copious urination

Eye Fatigue

Fatigue and shortness of breath

Dry Mouth

Dry mouth and throat

Weight Loss

Gradual weight loss despite normal eating

How It Addresses the Root Cause

Yu Ye Tang addresses a pattern where the body's Qi has become too weak to carry fluids to where they are needed, while Yin (the body's moistening and cooling resources) has also been depleted. This dual deficiency of Qi and Yin is the root mechanism behind the "wasting-thirst" (Xiao Ke 消渴) pattern this formula targets.

In a healthy body, the Spleen generates Qi from food and drink and "raises the clear" — meaning it sends nourishing substances upward to the Lungs, which then distribute moisture throughout the body. The Kidneys, meanwhile, store essence and prevent precious fluids from leaking away in the urine. When the Spleen's Qi becomes weak, it can no longer lift fluids upward to moisten the mouth and throat, resulting in persistent thirst that drinking water alone cannot relieve. At the same time, deficient Yin means there is not enough "raw material" of moisture in the body, and mild internal Heat from this Yin deficiency further dries what little fluid remains. The Kidneys, also weakened, lose their ability to hold fluids in, so urine becomes frequent and copious — sometimes containing a sweet substance (sugar), which Zhang Xichun astutely recognized as a hallmark of what Western medicine calls diabetes.

The vicious cycle is clear: weak Qi fails to distribute fluids → thirst intensifies → more drinking but fluids are not retained → frequent urination depletes fluids further → Yin deficiency worsens → mild Heat arises → more fluid damage. The formula breaks this cycle by simultaneously strengthening the Qi that lifts and distributes fluids, replenishing the Yin that has been consumed, gently clearing the deficiency Heat, and tightening the Kidney gate to reduce fluid loss through excessive urination.

Formula Properties

Temperature

Slightly Cool

Taste Profile

Predominantly sweet and slightly bitter — sweet from Shan Yao and Huang Qi to tonify and generate fluids, bitter from Zhi Mu to clear Heat, with a sour note from Wu Wei Zi to astringe and retain fluids.

Target Organs
Spleen Lungs Kidneys Stomach
Channels Entered
Spleen Lung Kidney Stomach

Formula Origin

Yi Xue Zhong Zhong Can Xi Lu (医学衷中参西录, Records of Heart-Felt Experiences in Medicine with Reference to the West) by Zhang Xichun

This is just partial information on the formula's TCM properties. More detailed information is available on the formula's dedicated page

Ingredients in Yu Ye Tang

Detailed information about each herb in Yu Ye Tang and their roles

Shan Yao
Shan Yao

Chinese yam

Dosage: 30g

Temperature Neutral
Taste Sweet (甘 gān)
Organ Affinity Spleen, Lungs, Kidneys
Parts Used Rhizome (根茎 gēn jīng)
Role in Yu Ye Tang

Used raw (sheng) at the heaviest dose in the formula. Tonifies the Spleen, benefits the Lungs, and secures the Kidneys. Its rich, nourishing quality generates fluids and moistens dryness, directly addressing the core mechanism of fluid depletion. Zhang Xichun considered raw Shan Yao his single most important herb for wasting-thirst.

Huang Qi
Huang Qi

Astragalus root

Dosage: 15g

Temperature Slightly Warm
Taste Sweet (甘 gān)
Organ Affinity Spleen, Lungs
Parts Used Root (根 gēn)
Role in Yu Ye Tang

Used raw (sheng) to powerfully tonify Qi and raise the clear Yang of the Spleen and Stomach. When Qi is strong enough to rise, it carries fluids upward to the Lungs so they can be distributed throughout the body, relieving thirst. Paired with Ge Gen, its ascending action is amplified.

Zhi Mu
Zhi Mu

Anemarrhena rhizome

Dosage: 18g

Temperature Cold
Taste Bitter (苦 kǔ), Sweet (甘 gān)
Organ Affinity Lungs, Stomach, Kidneys
Parts Used Rhizome (根茎 gēn jīng)
Role in Yu Ye Tang

Clears Heat, nourishes Yin, and moistens dryness in the Lungs, Stomach, and Kidneys. Balances the warm, ascending nature of Huang Qi so the formula does not become overly drying. Zhang Xichun likened the pairing of Huang Qi (warm, rising Yang) with Zhi Mu (cool, moistening Yin) to the meeting of rising warmth and gathering clouds that produce rain.

Tian Hua Fen
Tian Hua Fen

Trichosanthes root

Dosage: 9g

Temperature Cool
Taste Sweet (甘 gān), Bitter (苦 kǔ)
Organ Affinity Lungs, Stomach
Parts Used Root (根 gēn)
Role in Yu Ye Tang

Clears Heat, generates fluids, and relieves thirst. Works alongside Zhi Mu to nourish true Yin and moisten the Lungs and Stomach. Its cooling, fluid-generating action directly addresses the dryness and thirst symptoms.

Ge Gen
Ge Gen

Kudzu root

Dosage: 4.5g

Temperature Cool
Taste Sweet (甘 gān), Acrid / Pungent (辛 xīn)
Organ Affinity Spleen, Stomach, Lungs
Parts Used Root (根 gēn)
Role in Yu Ye Tang

Raises the clear Yang of the Spleen and Stomach, promoting the upward distribution of fluids to relieve thirst. Assists Huang Qi in elevating Qi so that fluids can reach the Lungs. Also generates fluids and clears mild Heat.

Ji Nei Jin
Ji Nei Jin

Chicken gizzard lining

Dosage: 6g

Temperature Neutral
Taste Sweet (甘 gān)
Organ Affinity Spleen, Stomach, Small Intestine, Urinary Bladder
Parts Used Animal — part (动物部分 dòng wù bù fèn)
Role in Yu Ye Tang

Strengthens the Spleen and Stomach's digestive and transformative capacity. Zhang Xichun specifically noted that in wasting-thirst the urine contains sugar, and this herb helps the Spleen and Stomach transform the sugary substances in food into usable fluids. Also assists in reducing frequent urination.

Wu Wei Zi
Wu Wei Zi

Schisandra berry

Dosage: 9g

Temperature Warm
Taste Sour (酸 suān), Sweet (甘 gān)
Organ Affinity Lungs, Heart, Kidneys
Parts Used Fruit (果 guǒ / 果实 guǒ shí)
Role in Yu Ye Tang

Its sour, astringent nature secures the Kidney gate, preventing fluids from leaking downward as excessive urination. Assists Shan Yao in consolidating the Kidneys and retaining Yin fluids, ensuring the generated fluids are not immediately lost.

Modern Research (3 studies)

  • Network pharmacology and experimental study on mechanism of Yuye Decoction against T2DM (2023)
  • Integrated 16S rRNA sequencing and metabolomics analysis of Yu-Ye Tang on T2DM rats (2023)
See all research on the formula page

Usage & Safety

How to use this formula and important safety information

Important Medical Disclaimer

The information provided here is for educational purposes only and is not intended as medical advice or to replace consultation with a qualified healthcare professional. This formula is a dietary supplement and has not been evaluated by the FDA. It is not intended to diagnose, treat, cure, or prevent any disease.

Always consult with a qualified healthcare provider, particularly if you are pregnant, nursing, have a medical condition, or are taking other medications. Discontinue use and consult your healthcare provider if you experience any adverse reactions.

Recommended Dosage

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Best Time to Take

30 minutes before meals, twice daily (morning and evening), to optimize absorption and the formula's Qi-raising action.

Typical Duration

Often taken for 4–12 weeks as a course of treatment, then reassessed. Chronic conditions like diabetes may require intermittent long-term use with periodic practitioner review.

Dietary Advice

Avoid sugary, greasy, and rich foods that burden the Spleen and generate Dampness or Heat, as these directly worsen the wasting-thirst pattern this formula treats. Favour whole grains, light vegetables, yams, mung beans, and foods that gently nourish Yin such as pears, lily bulb, and white fungus (Tremella). Alcohol and spicy foods should be minimized, as they generate Heat and damage Yin. Cold and raw foods should be eaten in moderation to protect the Spleen's transforming function. Regular, moderate-sized meals are preferable to large or irregular eating patterns.

Special Populations

Pregnancy

Generally considered safe during pregnancy based on its ingredient profile. None of the seven herbs (Shan Yao, Huang Qi, Zhi Mu, Tian Hua Fen, Ge Gen, Wu Wei Zi, Ji Nei Jin) are classified as strongly contraindicated in pregnancy. However, Tian Hua Fen (Trichosanthes root) has historically been noted for potential abortifacient effects when used in concentrated injectable preparations (Tian Hua Fen protein), though this concern does not apply to the standard oral decoction doses used in this formula. As a precaution, pregnant women should only take this formula under the guidance of a qualified practitioner, and the Tian Hua Fen dosage should be kept moderate.

Breastfeeding

No specific safety concerns have been identified for breastfeeding mothers. The formula's seven herbs are food-grade or commonly used tonics (Shan Yao is a food, Huang Qi is a widely consumed tonic, Ji Nei Jin is an animal product). None are known to produce toxic metabolites that transfer through breast milk in clinically significant amounts. The formula's gentle Qi-tonifying and Yin-nourishing actions are unlikely to negatively affect milk production or quality. However, the cooling nature of Zhi Mu and Tian Hua Fen means the formula should be discontinued if the infant develops loose stools or digestive upset. Use under practitioner guidance is recommended.

Pediatric Use

Yu Ye Tang is not a formula traditionally associated with pediatric use, as wasting-thirst (Xiao Ke) with Qi-Yin deficiency is primarily an adult condition. In rare cases where it may be considered for adolescents with diabetes showing clear Qi-Yin deficiency signs, dosages should be reduced to approximately one-third to one-half of adult doses depending on age and body weight. Zhi Mu (Anemarrhena) is cold in nature and should be used cautiously in children, whose digestive systems are inherently more delicate. The formula is generally not suitable for children under 12 without specific practitioner guidance. For younger children with thirst or frequent urination, simpler and milder approaches should be considered first.

Drug Interactions

Oral hypoglycemic agents and insulin: Yu Ye Tang has demonstrated blood-glucose-lowering effects in both animal studies and clinical practice. When combined with pharmaceutical diabetes medications (metformin, sulfonylureas, insulin, etc.), there is a potential for additive hypoglycemic effects. Blood glucose should be monitored closely and medication dosages may need adjustment.

Anticoagulant and antiplatelet drugs: Huang Qi (Astragalus) and Ge Gen (Pueraria) have mild effects on blood circulation. Patients taking warfarin, aspirin, or other blood-thinning medications should use this formula with caution and have their clotting parameters monitored.

Immunosuppressants: Huang Qi is known to modulate immune function (generally upregulating it). This could theoretically interfere with immunosuppressive therapy in transplant patients or those on such medications for autoimmune conditions.

Contraindications

Avoid

Damp-Heat accumulation or excess Heat patterns (湿热内蕴, 实热证). This formula tonifies and moistens, which can worsen conditions where Dampness or excess pathogenic Heat is the primary problem. Signs include a greasy yellow tongue coating, a slippery rapid pulse, and a feeling of heaviness in the body.

Avoid

Cold-Dampness obstructing the Spleen and Stomach. When the digestive system is bogged down by Cold and Dampness (loose stools, heavy sensation, thick white greasy tongue coating), the Yin-nourishing and cooling herbs in this formula may further impair digestive function.

Caution

Excess-type Xiao Ke (wasting-thirst) due to Lung-Stomach blazing Heat. When vigorous pathogenic Heat is the dominant factor with a strong, forceful pulse, this formula's gentle tonifying approach is insufficient and inappropriate. Formulas that strongly clear Heat and drain Fire should be used instead.

Caution

Severe Kidney Yang deficiency with cold limbs, clear profuse urine, and a deep slow pulse. This formula primarily addresses Qi and Yin deficiency and contains cooling herbs (Zhi Mu, Tian Hua Fen) that may further damage Yang. Kidney Yang-warming formulas like Jin Gui Shen Qi Wan are more appropriate.

Caution

Active diarrhea or loose stools from Spleen deficiency. The large dose of Shan Yao and the cold nature of Zhi Mu may aggravate weak digestion in some patients. Dosages should be adjusted or Spleen-strengthening herbs added.

Cautions & Warnings

is typically safe for most individuals, but it can lead to side effects in some cases. Pregnant, nursing, or postpartum women, as well as those with liver conditions, should use this formula cautiously and preferably under professional supervision.

As with any Chinese herbal remedy, it is advisable to seek guidance from a qualified Traditional Chinese Medicine (TCM) practitioner before beginning treatment with Liu Wei Di Huang Wan.

Product Details

Manufacturing, supplier, and product specifications

Product Type

Granules

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Treasure of the East

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