Formula

Yu Lin Fang

Rehmannia & Cuscuta Combination | 毓麟方

Also known as:

Fertility Pearl , Offspring Nurturing Pearl , Nurturing Qi Lin Pearl , Yu Lin Wan , Fertility Eight Treasure Pill

Properties

Tonifying formulas · Warm

Key Ingredients

Shu Di Huang, Dang Gui, Tu Si Zi

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

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About This Formula

Traditional Chinese Medicine background and properties

Formula Description

A classical fertility formula designed to nourish both Qi and Blood while warming the Kidneys and Liver. It is commonly used for women experiencing irregular periods, difficulty conceiving, low back pain, fatigue, and poor appetite that stem from underlying weakness of the body's vital substances and reproductive system.

Formula Category

Main Actions

  • Tonifies Qi and Generates Blood
  • Tonifies Kidney Yang
  • Tonifies the Liver
  • Secures the Chong and Ren Vessels
  • Regulates menstruation
  • Warms the Uterus and Promotes Fertility

TCM Patterns

In TCM, symptoms don't appear randomly — they cluster into recognizable patterns of disharmony that reveal what's out of balance in the body. Yu Lin Zhu is traditionally associated with these specific patterns.

The following describes this formula's classification within Traditional Chinese Medicine theory and is provided for educational purposes only.

Why Yu Lin Zhu addresses this pattern

When both Qi and Blood are deficient, the Penetrating (Chong) and Directing (Ren) vessels lack nourishment, leading to scanty or irregular menstruation, poor appetite, fatigue, and difficulty conceiving. Yu Lin Zhu addresses this through its Ba Zhen Tang core: Ren Shen and Bai Zhu tonify Qi and strengthen the Spleen to generate new Blood, while Shu Di Huang, Dang Gui, Bai Shao, and Chuan Xiong nourish, move, and regulate the Blood. Fu Ling supports Spleen function and prevents Dampness, while Zhi Gan Cao harmonizes. This dual Qi-Blood tonification restores the material basis for healthy menstruation and fertility.

A practitioner would look for one or more of these signs

Irregular Menstruation

Periods delayed, scanty, or intermittent

Dull Pale Complexion

Pale or sallow face

Eye Fatigue

Persistent tiredness and low stamina

Poor Appetite

Reduced appetite with weight loss

Dizziness

Lightheadedness from Blood deficiency

Pale Tongue

Pale tongue with thin white coating

How It Addresses the Root Cause

Yu Lin Zhu addresses a pattern where both the body's foundational reserves (the "prenatal" Kidney system) and its day-to-day resource production (the "postnatal" Spleen and Stomach system) have become depleted. This dual deficiency creates a cascade of problems centred on reproductive function.

The Kidneys store Essence (Jing), which is the material basis for fertility, egg maturation, and the warming "ministerial fire" (Ming Men) that sustains reproductive vitality. When Kidney Yang and Essence are insufficient, the uterus and the Chong and Ren vessels — the two extraordinary meridians that govern menstruation and conception — lose their warmth and nourishment. The result is a "cold uterus" that cannot properly sustain a menstrual cycle or support implantation. Meanwhile, deficient Spleen and Stomach Qi means the body cannot adequately produce new Qi and Blood from food. Since menstrual Blood is ultimately derived from Spleen-generated Blood, this deficiency leads to scanty, pale, delayed periods, poor appetite, and general emaciation.

Liver Blood also becomes depleted in this picture because the Liver depends on Kidney Essence for its root nourishment and on Spleen-generated Blood for its reservoir. As the Liver stores Blood and regulates its release for menstruation, its insufficiency further disrupts the cycle. The net result is a body that lacks both the warmth and the substance needed to menstruate regularly and conceive: the Chong vessel has insufficient Blood to fill, the Ren vessel has insufficient Qi to hold, and the Kidney's reproductive fire is too dim to catalyse new life. This is why the classical indication describes a thin, weak woman with irregular or absent periods, low back pain, poor appetite, and infertility.

Formula Properties

Temperature

Warm

Taste Profile

Predominantly sweet and warm — sweet to tonify Qi and Blood, with pungent warmth from Chuan Jiao and Du Zhong to warm the Kidneys, balanced by the mild bitterness and astringency of Bai Shao to preserve Yin and prevent excessive dispersal.

Target Organs
Kidneys Liver Spleen Uterus
Channels Entered
Kidney Liver Spleen Stomach Chong Mai (冲脉) Penetrating Vessel Ren Mai (任脉) Conception Vessel

Formula Origin

Jing Yue Quan Shu (景岳全书), Volume 51, by Zhang Jiebin

This is just partial information on the formula's TCM properties. More detailed information is available on the formula's dedicated page

Ingredients in Yu Lin Fang

Detailed information about each herb in Yu Lin Fang and their roles

Kings
Deputies
Assistants
Envoys
Shu Di Huang
Shu Di Huang

Prepared Rehmannia root

Dosage: 12 - 24g

Temperature Slightly Warm
Taste Sweet (甘 gān)
Organ Affinity Liver, Kidneys
Parts Used Tuber (块茎 kuài jīng / 块根 kuài gēn)
Role in Yu Lin Fang

Nourishes Blood and Kidney Yin, fills the Essence, and serves as the primary Blood tonic in the formula. As the highest-dose herb, it anchors the formula's ability to replenish the material foundation needed for conception.

Dang Gui
Dang Gui

Chinese Angelica root

Dosage: 12 - 24g

Temperature Warm
Taste Sweet (甘 gān), Acrid / Pungent (辛 xīn)
Organ Affinity Liver, Heart, Spleen
Parts Used Root (根 gēn)
Role in Yu Lin Fang

Tonifies and invigorates Blood, regulates menstruation, and works alongside Shu Di Huang to address the Blood deficiency at the core of the pattern. Its mild Blood-moving quality prevents stagnation from the heavy tonification in the formula.

Tu Si Zi
Tu Si Zi

Dodder seed

Dosage: 12 - 24g

Temperature Neutral
Taste Acrid / Pungent (辛 xīn), Sweet (甘 gān)
Organ Affinity Liver, Kidneys, Spleen
Parts Used Seed (种子 zhǒng zǐ / 子 zǐ / 仁 rén)
Role in Yu Lin Fang

Tonifies Kidney Yang and Yin, secures Essence, and benefits the Liver. As the highest-dose herb alongside Dang Gui and Shu Di Huang, it directly addresses Kidney deficiency and strengthens the reproductive axis (Chong and Ren vessels).

Ren Shen
Ren Shen

Ginseng root

Dosage: 6 - 12g

Temperature Slightly Warm
Taste Sweet (甘 gān), Bitter (苦 kǔ)
Organ Affinity Spleen, Lungs, Heart, Kidneys
Parts Used Root (根 gēn)
Role in Yu Lin Fang

Powerfully tonifies Qi, strengthens the Spleen and Stomach to generate Qi and Blood from food. Serves as the core Qi tonic to support the Blood-nourishing herbs.

Bai Zhu
Bai Zhu

White Atractylodes rhizome

Dosage: 6 - 12g

Temperature Warm
Taste Bitter (苦 kǔ), Sweet (甘 gān)
Organ Affinity Spleen, Stomach
Parts Used Rhizome (根茎 gēn jīng)
Role in Yu Lin Fang

Strengthens the Spleen and dries Dampness, supporting the digestive transformation needed to produce Qi and Blood. Complements Ren Shen in building the postnatal foundation.

Lu
Lu Jiao Shuang (Degelatinated Deer Antler)

Dosage: 6 - 12g

Role in Yu Lin Fang

Warms Kidney Yang, tonifies Essence and Blood, and strengthens the Governing and Penetrating vessels. Supports the Kidney-warming function alongside Tu Si Zi and Du Zhong.

Du Zhong
Du Zhong

Eucommia bark

Dosage: 6 - 12g

Temperature Warm
Taste Sweet (甘 gān)
Organ Affinity Liver, Kidneys
Parts Used Bark (皮 pí / 树皮 shù pí)
Role in Yu Lin Fang

Tonifies the Liver and Kidneys, strengthens the sinews and bones, and stabilizes pregnancy. Reinforces the Kidney-tonifying action and addresses lower back soreness.

Fu Ling
Fu Ling

Poria

Dosage: 6 - 12g

Temperature Neutral
Taste Sweet (甘 gān), Bland (淡 dàn)
Organ Affinity Heart, Lungs, Spleen, Kidneys
Parts Used Fungus / Mushroom (菌类 jūn lèi)
Role in Yu Lin Fang

Strengthens the Spleen and drains Dampness, supporting digestion and preventing the heavy tonifying herbs from causing stagnation or dampness accumulation.

Bai Shao
Bai Shao

White peony root

Dosage: 6 - 12g

Temperature Slightly Cool
Taste Bitter (苦 kǔ), Sour (酸 suān)
Organ Affinity Liver, Spleen
Parts Used Root (根 gēn)
Role in Yu Lin Fang

Nourishes Blood, softens the Liver, and regulates menstruation. Pairs with Dang Gui to tonify and harmonize the Blood, and moderates any drying effects.

Chuan Xiong
Chuan Xiong

Szechuan lovage rhizome

Dosage: 3 - 6g

Temperature Warm
Taste Acrid / Pungent (辛 xīn)
Organ Affinity Liver, Gallbladder, Pericardium
Parts Used Rhizome (根茎 gēn jīng)
Role in Yu Lin Fang

Invigorates Blood and moves Qi, preventing stagnation from the many heavy tonifying herbs. Known as the 'Qi herb within the Blood division,' it ensures smooth flow of the newly generated Blood.

Hua Jiao
Hua Jiao

Sichuan pepper

Dosage: 3 - 6g

Temperature Warm
Taste Acrid / Pungent (辛 xīn)
Organ Affinity Spleen, Stomach, Kidneys
Parts Used Peel / Rind (皮 pí / 果皮 guǒ pí)
Role in Yu Lin Fang

Warms the middle and lower body, dispels Cold from the uterus, and helps restore warmth to the reproductive organs. Specifically addresses uterine Cold that contributes to infertility.

Gan Cao
Gan Cao

Licorice root

Dosage: 3 - 6g

Temperature Neutral
Taste Sweet (甘 gān)
Organ Affinity Heart, Lungs, Spleen, Stomach
Parts Used Root (根 gēn)
Role in Yu Lin Fang

Tonifies Spleen Qi, harmonizes the actions of all herbs in the formula, and moderates the warm and moving properties of the other ingredients.

Modern Research (2 studies)

  • Effects of Yu Linzhu on Ovarian Function and Oocyte Mitochondria in Natural Aging Mice (Preclinical Study, 2021)
  • Advances in Traditional Chinese Medicine for Managing Diminished Ovarian Reserve: Mechanisms and Clinical Insights (Review, 2025)
See all research on the formula page

Usage & Safety

How to use this formula and important safety information

Important Medical Disclaimer

The information provided here is for educational purposes only and is not intended as medical advice or to replace consultation with a qualified healthcare professional. This formula is a dietary supplement and has not been evaluated by the FDA. It is not intended to diagnose, treat, cure, or prevent any disease.

Always consult with a qualified healthcare provider, particularly if you are pregnant, nursing, have a medical condition, or are taking other medications. Discontinue use and consult your healthcare provider if you experience any adverse reactions.

Recommended Dosage

Instructions for safe storage and consumption

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Best Time to Take

On an empty stomach, 30–60 minutes before meals, twice daily (morning and evening). Classical instructions specify taking with warm water or mild wine.

Typical Duration

Typically taken for 2–4 months (approximately 3–6 menstrual cycles), reassessed each cycle by the practitioner. Discontinued upon confirmed pregnancy.

Dietary Advice

While taking this formula, favour warm, nourishing, easily digestible foods such as bone broth, congee, cooked root vegetables, lamb, and foods that support the Spleen and Kidneys (black sesame, walnuts, goji berries, kidney beans). Avoid cold and raw foods (salads, iced drinks, raw sushi, ice cream) as these can impair Spleen function and counteract the formula's warming strategy. Avoid greasy, deep-fried, or excessively rich foods that may generate Dampness and obstruct the already cloying nature of Shu Di Huang. Limit spicy-hot foods that could overstimulate the already warming herbs. Reduce caffeine and alcohol, which can disrupt hormonal balance and deplete Kidney Essence. The classical instruction specifies taking the pills on an empty stomach with warm water or mild wine (白汤 or 酒), suggesting the formula is best absorbed without competing food in the stomach.

Modern Usage

The formula invigorates the congenital Kidney Qi to stimulate sperm production while nourishing the acquired Spleen and Stomach Qi to generate Blood. Additionally, it promotes Blood circulation, regulates menstruation, and nourishes the Penetrating and Directing Vessel (Ren Mai and Chong Mai).

This harmonious interaction results in abundant Essence and a smooth flow in the Penetrating and Directing Vessel, allowing them to nourish each other. Consequently, the conditions are ideal for the union of sperm and egg, facilitating pregnancy.

Yu Lin Zhu is not only effective for treating gynecological conditions such as amenorrhea due to Blood Deficiency and infertility related to Kidney Deficiency, but it is also beneficial for addressing male infertility.

Special Populations

Pregnancy

This formula is specifically designed as a pre-conception treatment and should be discontinued once pregnancy is confirmed, unless a qualified practitioner advises otherwise. While several individual herbs in the formula (Du Zhong, Tu Si Zi, Bai Zhu) are actually considered beneficial during pregnancy and are used in fetal-calming formulas, others require caution. Chuan Jiao (Sichuan Pepper) is acrid and warming, and in large or prolonged doses could potentially stimulate uterine activity. Lu Jiao Shuang (Degelatinated Deer Antler) is a strong Yang tonic whose effects on early pregnancy are not well studied. The formula as a whole is strongly warming and tonifying, which may not be appropriate for all stages of pregnancy. The classical instructions indicate it is taken before conception and typically stopped once pregnancy occurs. Any continued use during pregnancy should only be under direct practitioner supervision with appropriate modifications.

Breastfeeding

No specific classical prohibitions exist against using Yu Lin Zhu during breastfeeding, and the formula's gentle tonifying nature is less likely to cause problems than formulas containing harsh or toxic substances. However, the formula is designed for pre-conception use in women with deficiency-type infertility, so there is rarely a clinical reason to prescribe it during lactation. The warming herbs Chuan Jiao and Lu Jiao Shuang transfer into breast milk to some degree, and their effects on nursing infants have not been formally studied. Ren Shen (Ginseng) may theoretically affect infant alertness or sleep through breast milk. If a breastfeeding woman has the pattern of Qi-Blood and Kidney deficiency that this formula addresses, a practitioner would typically select a simpler tonic formula more appropriate for the postpartum period rather than this fertility-focused prescription. Consult a qualified practitioner before use while breastfeeding.

Pediatric Use

Yu Lin Zhu is not appropriate for pediatric use. This formula is specifically designed to treat infertility and menstrual disorders in adult women of reproductive age, addressing deficiency patterns related to mature reproductive physiology. Children have not yet developed the reproductive systems that this formula targets, and the warming Kidney Yang tonics (Lu Jiao Shuang, Du Zhong, Chuan Jiao) are generally inappropriate for children's constitutions, which tend to run warm. There are no classical or modern indications for pediatric use of this formula.

Drug Interactions

Gan Cao (Licorice Root) in this formula contains glycyrrhizin, which has well-documented interactions with several drug classes:

  • Antihypertensives and diuretics: Glycyrrhizin can cause sodium retention and potassium loss (pseudoaldosteronism), potentially counteracting blood pressure medications and worsening hypokalaemia when combined with thiazide or loop diuretics.
  • Digoxin and cardiac glycosides: The potassium-depleting effect of licorice can increase the risk of digoxin toxicity.
  • Corticosteroids: Glycyrrhizin inhibits the enzyme 11-beta-hydroxysteroid dehydrogenase, which may potentiate the effects of corticosteroids.
  • Warfarin and anticoagulants: Dang Gui (Angelica sinensis) contains coumarins and may enhance anticoagulant effects, increasing bleeding risk.

Ren Shen (Ginseng) may interact with:

  • MAO inhibitors: Potential for headache, tremor, and manic episodes.
  • Hypoglycaemic agents: Ginseng may potentiate blood sugar-lowering effects of insulin or oral antidiabetics.
  • Immunosuppressants: Ginseng's immunomodulatory effects may theoretically reduce the efficacy of immunosuppressive drugs.

Patients taking fertility medications (clomiphene, letrozole, gonadotropins) should inform their prescribing physician before combining them with this formula, as the formula's hormonal effects may interact with ovulation-induction protocols.

Contraindications

Avoid

Infertility or menstrual irregularity caused by Damp-Heat, Phlegm obstruction, or Blood stasis as the primary pathology. This formula is strongly tonifying and warming, and using it in excess conditions can trap the pathogen and worsen the situation.

Avoid

Yin deficiency with pronounced Heat signs such as a distinctly red tongue, scanty dark urine, hot flashes, and night sweats. The warming herbs (Chuan Jiao, Lu Jiao Shuang, Du Zhong) can further damage Yin and aggravate deficiency Heat.

Avoid

Active infections or febrile illness. The formula's warm, tonifying nature can feed pathogenic Heat and should not be used during acute illness with fever.

Caution

Liver Qi stagnation with significant emotional disturbance, breast distension, and irritability as the dominant presentation. While deficiency may coexist, strong stagnation should be addressed first or the formula modified with Qi-moving herbs before using this heavily supplementing prescription.

Caution

Patients with Spleen deficiency and significant Dampness accumulation (heavy body, loose stools, thick greasy tongue coating). The rich, cloying herbs like Shu Di Huang may worsen Dampness and impair digestion. The formula may need modification with Dampness-drying herbs.

Caution

Hypertension or conditions where warming Yang-tonifying herbs are inappropriate. Ingredients like Lu Jiao Shuang and Du Zhong can raise Yang and should be used cautiously in patients with Liver Yang rising.

Cautions & Warnings

Although this formula is typically safe for most individuals, it may cause side effects in some people. Pregnant women, nursing mothers, postpartum women, and those with liver disease should use the formula with caution.

As with any Chinese herbal remedy, it is advisable to seek guidance from a qualified TCM practitioner before beginning treatment.

Product Details

Manufacturing, supplier, and product specifications

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Granules

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