Formula

Yin Qiao Jie Du Wan

Lonicera & Forsythia Detox Combination | 银翘解毒丸

Also known as:

Yin Qiao Detoxification Pills

Key Ingredients

Jin Yin Hua, Lian Qiao

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

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About This Formula

Traditional Chinese Medicine background and properties

Formula Description

A widely used formula for the early stages of colds and flu caused by Wind-Heat, especially when fever, sore throat, headache, and thirst are prominent. It works by gently releasing Heat from the body's surface while clearing toxins and soothing the throat. It is the pill form of the classic Yin Qiao San (Honeysuckle and Forsythia Powder).

Formula Category

Main Actions

  • Disperses Wind-Heat
  • Clears Heat and Resolves Toxicity
  • Benefits the Throat
  • Diffuses Lung Qi

TCM Patterns

In TCM, symptoms don't appear randomly — they cluster into recognizable patterns of disharmony that reveal what's out of balance in the body. Yin Qiao Jie Du Wan is traditionally associated with these specific patterns.

The following describes this formula's classification within Traditional Chinese Medicine theory and is provided for educational purposes only.

Why Yin Qiao Jie Du Wan addresses this pattern

This is the primary pattern Yin Qiao Jie Du Wan was designed for. When Wind-Heat invades the body, it first lodges in the Lungs and the Defensive (Wei) Qi level, disrupting the Lung's ability to regulate the opening and closing of pores. This causes fever, mild chills, headache, and absent or scanty sweating. The Heat rises to scorch the throat, causing pain and dryness. The Lungs lose their descending function, producing cough. Jin Yin Hua and Lian Qiao clear the Heat and toxins, Bo He and Niu Bang Zi disperse the Wind-Heat and soothe the throat, while Jing Jie and Dan Dou Chi help release the pathogen through the Exterior. Jie Geng restores the Lung's descending function and addresses cough. The formula is designed to gently open the Exterior to let the pathogen leave while simultaneously clearing the Heat that is building up.

A practitioner would look for one or more of these signs

Fever

Fever with mild chills, Heat predominating over cold

Sore Throat

Sore, red, swollen throat

Headaches

Headache from Wind-Heat

Hypochondrial Pain That Is Worse On Coughing And Breathing

Cough with possible yellow sputum

Thirst

Thirst with desire for cool drinks

Swelling

No sweat or scanty sweating

How It Addresses the Root Cause

Yin Qiao Jie Du Wan targets the earliest stage of a warm-pathogen illness (温病, wen bing) — specifically, a Wind-Heat invasion at the Wei (Defensive) level. In TCM theory, warm pathogens enter the body through the nose and mouth, first attacking the Lungs and the body's outermost defensive layer. Because the Lungs govern the skin and body surface and control the opening and closing of pores, when Wind-Heat lodges at this level it disrupts the Lungs' ability to properly regulate the exterior. The result is fever, because the body's defensive Qi is struggling against the invading pathogen, yet the Heat component prevents effective sweating — so the person feels hot, may have little or no sweat, and experiences a mild aversion to wind rather than the strong chills seen in Cold-type illnesses.

The Heat pathogen also rises upward and affects the throat and head, causing sore throat, headache, and thirst. Because the Lungs' descending and dispersing function is impaired, coughing may occur. The tongue tip (connected to the Heart and Upper Burner) turns red, and the pulse floats (indicating the pathogen is at the surface) and is rapid (indicating Heat). The key pathological dynamic is Heat trapped at the surface level that needs to be vented outward and cleared simultaneously. If not addressed promptly, the warm pathogen can penetrate deeper — moving from the Defensive level to the Qi, Nutritive (Ying), or Blood levels — making treatment progressively more difficult. This is why early intervention with a formula that both releases the exterior and clears Heat-toxin is so critical.

Formula Properties

Temperature

Cool

Taste Profile

Predominantly pungent and slightly bitter with mild sweet undertones — pungent to disperse and release the exterior, bitter to clear Heat and dry, sweet to harmonize and protect the Stomach.

Target Organs
Lungs Heart Stomach
Channels Entered
Lung Heart Stomach

Formula Origin

Wen Bing Tiao Bian (温病条辨, Systematic Differentiation of Warm Diseases) by Wu Jutong (吴鞠通)

This is just partial information on the formula's TCM properties. More detailed information is available on the formula's dedicated page

Ingredients in Yin Qiao Jie Du Wan

Detailed information about each herb in Yin Qiao Jie Du Wan and their roles

Kings
Deputies
Assistants
Envoys
Jin Yin Hua
Jin Yin Hua

Honeysuckle flower

Dosage: 15 - 30g

Temperature Cold
Taste Sweet (甘 gān)
Organ Affinity Lungs, Heart, Stomach, Large Intestine
Parts Used Flower bud (花蕾 huā lěi)
Role in Yin Qiao Jie Du Wan

The primary King herb. Its sweet, cold nature and aromatic quality allow it to both clear Heat and resolve toxins while gently dispersing pathogens from the body's Defensive (Wei) level. It is used at the highest dose in the formula to powerfully address the core pathomechanism of Wind-Heat invasion.

Lian Qiao
Lian Qiao

Forsythia fruit

Dosage: 15 - 30g

Temperature Slightly Cool
Taste Bitter (苦 kǔ)
Organ Affinity Lungs, Heart, Small Intestine
Parts Used Fruit (果 guǒ / 果实 guǒ shí)
Role in Yin Qiao Jie Du Wan

The second King herb, paired with Jin Yin Hua. It clears Heat, resolves toxins, and disperses clumped Heat. Its bitter, slightly acrid, and cool nature complements Jin Yin Hua, and together they form the core therapeutic axis of the formula, giving it both its name and its primary action.

Bo He
Bo He

Mint herb

Dosage: 6 - 18g

Temperature Cool
Taste Acrid / Pungent (辛 xīn), Aromatic (芳香 fāng xiāng)
Organ Affinity Lungs, Liver
Parts Used Whole plant / Aerial parts (全草 quán cǎo)
Role in Yin Qiao Jie Du Wan

Acrid and cool, it assists the King herbs by dispersing Wind-Heat from the head and eyes, clearing the head, soothing the throat, and promoting the venting of pathogens from the body surface.

Niu Bang Zi
Niu Bang Zi

Burdock fruit

Dosage: 9 - 18g

Temperature Cold
Taste Acrid / Pungent (辛 xīn), Bitter (苦 kǔ)
Organ Affinity Lungs, Stomach
Parts Used Seed (种子 zhǒng zǐ / 子 zǐ / 仁 rén)
Role in Yin Qiao Jie Du Wan

Acrid, bitter, and cold, it disperses Wind-Heat and clears the throat. Especially important for sore, swollen throat, a hallmark symptom of this pattern. It also helps ventilate Lung Qi and promote the expression of rashes when relevant.

Jing Jie
Jing Jie

Schizonepeta herb

Dosage: 6 - 12g

Temperature Slightly Warm
Taste Acrid / Pungent (辛 xīn), Aromatic (芳香 fāng xiāng)
Organ Affinity Lungs, Liver
Parts Used Whole plant / Aerial parts (全草 quán cǎo)
Role in Yin Qiao Jie Du Wan

Though technically acrid and slightly warm, Jing Jie is mild and non-drying. Within this cool formula, its warmth is restrained by the King herbs while its acrid dispersing power strengthens the formula's ability to release the Exterior and push pathogens outward.

Dan Dou Chi
Dan Dou Chi

Fermented soybean

Dosage: 9 - 15g

Temperature Cool
Taste Bitter (苦 kǔ), Acrid / Pungent (辛 xīn)
Organ Affinity Lungs, Stomach
Parts Used Processed / Derived product (加工品 jiā gōng pǐn)
Role in Yin Qiao Jie Du Wan

Acrid and slightly warm, it works with Jing Jie to enhance the formula's ability to release pathogens through the Exterior. Though mildly warm, it is gentle and non-drying, and the cool King herbs keep its warmth in check. Together these two slightly warm herbs embedded among cool herbs are a hallmark of this formula's design.

Jie Geng
Jie Geng

Platycodon root

Dosage: 6 - 18g

Temperature Neutral
Taste Bitter (苦 kǔ), Acrid / Pungent (辛 xīn)
Organ Affinity Lungs
Parts Used Root (根 gēn)
Role in Yin Qiao Jie Du Wan

Opens and diffuses Lung Qi, stops coughing, and benefits the throat. It also functions as a guide herb, directing the formula's therapeutic actions upward to the Lungs and throat where Wind-Heat lodges.

Dan Zhu Ye
Dan Zhu Ye

Lophatherum

Dosage: 6 - 12g

Temperature Cold
Taste Sweet (甘 gān), Bland (淡 dàn)
Organ Affinity Heart, Stomach, Small Intestine
Parts Used Whole plant / Aerial parts (全草 quán cǎo)
Role in Yin Qiao Jie Du Wan

Sweet, bland, and cold, it clears Heat from the Upper Burner and generates fluids to relieve thirst. It also provides a mild route for draining Heat downward through urination, creating a secondary exit path for the pathogenic Heat.

Gan Cao
Gan Cao

Licorice root

Dosage: 6 - 15g

Temperature Neutral
Taste Sweet (甘 gān)
Organ Affinity Heart, Lungs, Spleen, Stomach
Parts Used Root (根 gēn)
Role in Yin Qiao Jie Du Wan

Harmonizes all the herbs in the formula, protects the Stomach from the cold and bitter herbs, and works synergistically with Jie Geng to soothe and clear the throat. Its sweet nature also helps preserve fluids.

Modern Research (3 studies)

  • RCT: Herbal medicines (Eunkyosan/Yin Qiao San and Samsoeum/Shen Su Yin) for treating the common cold (2023)
  • Systematic review and meta-analysis: Yinqiao powder combined with western medicine for pneumonia (2021)
See all research on the formula page

Usage & Safety

How to use this formula and important safety information

Important Medical Disclaimer

The information provided here is for educational purposes only and is not intended as medical advice or to replace consultation with a qualified healthcare professional. This formula is a dietary supplement and has not been evaluated by the FDA. It is not intended to diagnose, treat, cure, or prevent any disease.

Always consult with a qualified healthcare provider, particularly if you are pregnant, nursing, have a medical condition, or are taking other medications. Discontinue use and consult your healthcare provider if you experience any adverse reactions.

Recommended Dosage

Instructions for safe storage and consumption

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Best Time to Take

Take 2–3 times daily between meals (about 30–60 minutes before or after eating). In acute cases with high fever, the classical method recommends more frequent dosing — every 2–3 hours for severe cases — rather than larger individual doses.

Typical Duration

Acute use: 1–3 days for mild cases, up to 5–7 days maximum. Discontinue once symptoms resolve or if no improvement after 3 days.

Dietary Advice

Avoid greasy, fried, and rich foods, which generate Heat and Dampness and can obstruct the formula's light, dispersing action. Avoid alcohol and smoking. Avoid spicy-hot foods (chili, pepper, ginger, lamb) that could add Heat and worsen the condition. Avoid cold, raw foods and iced drinks, which can impair the Stomach's ability to process the herbs. Favor light, easily digestible meals such as congee (rice porridge), clear soups, and steamed vegetables. Drink plenty of warm fluids to support the body's ability to generate a light sweat and expel the pathogen. Fresh pear, watermelon (in small amounts), and mung bean soup are traditionally considered helpful during Wind-Heat conditions.

Modern Usage

With its pungent and cooling properties, this formula is designed to release the Exterior, dispel Wind, clear Heat, and eliminate Toxins. It soothes the throat, alleviates thirst, and helps to diffuse Lung Qi, effectively addressing symptoms like fever, headache, cough, dry mouth, and sore throat.
Similar to Yin Qiao San, the primary herbs in this formula are Jin Yin Hua (Honeysuckle) and Lian Qiao (Forsythia), but Yin Qiao Jie Du Wan (Yin Qiao Detoxification Pills) is known for its stronger Heat-clearing and detoxifying capabilities. In traditional Chinese medicine, this formula is widely used in hospitals during pandemic outbreaks and the cold and flu season.

Special Populations

Pregnancy

Generally considered low risk for short-term acute use, but caution is advised. The formula contains dispersing, exterior-releasing herbs (Bo He/Mint, Jing Jie/Schizonepeta, Niu Bang Zi/Burdock seed) whose moving, outward-directing nature could theoretically be undesirable in pregnancy. Niu Bang Zi in particular has a slippery, descending quality. While none of the nine herbs are classified as strongly contraindicated in pregnancy, the overall dispersing action warrants consultation with a qualified practitioner before use. Pregnant women should not self-medicate with this formula.

Breastfeeding

Likely safe for short-term use during breastfeeding when used at standard doses for acute conditions. The formula's herbs are generally mild and have been used traditionally in postpartum and breastfeeding populations for acute Wind-Heat conditions. However, Bo He (Mint) has aromatic volatile oils that may transfer to breast milk and could theoretically affect the nursing infant's digestion. Gan Cao (Licorice) in prolonged or excessive use could affect fluid balance. For short courses of 3–5 days at standard doses, significant risk is low, but consulting a practitioner is recommended. Discontinue if the infant shows any signs of digestive upset or fussiness.

Pediatric Use

Yin Qiao Jie Du Wan can be used in children, with appropriate dose reduction based on age and body weight. A common guideline for concentrated pill forms: children aged 1–3 years may take approximately one-quarter of the adult dose; ages 3–7 approximately one-third; ages 7–12 approximately one-half. For teapill forms, children over 6 are typically given 4–5 pills three times daily (compared to 8 pills for adults). Children under 1 year should not be given this formula without direct practitioner supervision. The pills can be crushed and mixed with a small amount of warm water if the child cannot swallow them whole. A pilot study in Singapore demonstrated tolerability of Yin Qiao San in children as young as 1 year for fever management. As with adults, this formula should only be used for Wind-Heat patterns, not for colds with prominent chills and clear runny nose. Discontinue after 3 days if symptoms do not improve.

Drug Interactions

Gan Cao (Licorice root) is the most pharmacologically active herb in terms of drug interactions in this formula. Glycyrrhizin in licorice can cause pseudoaldosteronism (sodium retention, potassium loss) and may interact with: antihypertensives (reducing their effectiveness), diuretics (especially potassium-depleting types like furosemide or hydrochlorothiazide, compounding potassium loss), digoxin (hypokalemia increases toxicity risk), and corticosteroids (potentiating mineralocorticoid effects). These interactions are mainly relevant with prolonged use rather than the short 3–7 day courses typical for this formula.

Bo He (Mint) contains volatile oils that may affect cytochrome P450 enzyme activity (particularly CYP3A4), potentially altering the metabolism of drugs processed through this pathway. Niu Bang Zi (Burdock seed) has mild hypoglycemic properties and could theoretically enhance the effects of diabetes medications. Patients on anticoagulant or antiplatelet therapy should use caution, as several herbs in the formula (Jin Yin Hua, Lian Qiao) have mild anti-inflammatory effects that could have additive effects.

For short-term acute use (3–5 days), clinically significant interactions are unlikely in most patients, but those on the medications listed above should inform their healthcare provider.

Contraindications

Avoid

Wind-Cold common cold (presenting with strong chills, no thirst, clear nasal discharge, body aches, white tongue coating, and tight pulse). This formula is cool in nature and would worsen a Cold-type condition.

Avoid

Deficiency-Cold of the Spleen and Stomach with chronic loose stools, poor appetite, or cold limbs. The cool, dispersing nature of this formula can further damage weakened digestive function.

Caution

Patients who are sweating profusely. Excessive exterior-releasing action may further deplete Qi and fluids in someone already losing fluids through heavy sweating.

Caution

Diabetes patients should exercise caution, particularly with honey-pill (蜜丸) formulations that contain significant sugar content. Consult a practitioner before use.

Caution

Should not be taken concurrently with tonic or nourishing (滋补) Chinese herbal medicines, as rich, cloying herbs can trap the pathogen and obstruct the exterior-releasing action of the formula.

Caution

If symptoms persist beyond 3 days without improvement, or fever exceeds 38.5°C, the formula should be discontinued and medical attention sought, as this may indicate a deeper pathological stage requiring different treatment.

Cautions & Warnings

Although this formula is typically safe for most individuals, it may cause side effects in some people. Pregnant women, nursing mothers, postpartum women, and those with liver disease should use the formula with caution.

As with any Chinese herbal remedy, it is advisable to seek guidance from a qualified TCM practitioner before beginning treatment.

Product Details

Manufacturing, supplier, and product specifications

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