Formula

Wu Pi Yin

Five Peel Decoction | 五皮饮

Also known as:

Wu Pi San (五皮散, Five-Peel Powder)

Key Ingredients

Fu Ling Pi

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

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About This Formula

Traditional Chinese Medicine background and properties

Formula Description

A classical formula made entirely from plant peels, designed to reduce swelling and fluid retention throughout the body. It gently promotes urination and supports the body's ability to move and transform fluids, making it especially useful for generalized puffiness, abdominal bloating, and difficult urination caused by sluggish fluid metabolism.

Formula Category

Main Actions

  • Promotes Urination and Reduces Edema
  • Transforms Dampness and Moves Qi
  • Strengthens the Spleen
  • Descends Lung Qi to open the water pathways
  • Moves Qi and Relieves Distension

TCM Patterns

In TCM, symptoms don't appear randomly — they cluster into recognizable patterns of disharmony that reveal what's out of balance in the body. Wu Pi Yin is traditionally associated with these specific patterns.

The following describes this formula's classification within Traditional Chinese Medicine theory and is provided for educational purposes only.

Why Wu Pi Yin addresses this pattern

When the Spleen's ability to transport and transform fluids breaks down, water and dampness accumulate and overflow into the skin and tissues. This produces generalized edema, a heavy feeling in the limbs, abdominal bloating, and reduced urination. Wu Pi Yin addresses this pattern by using Fu Ling Pi to drain dampness and support the Spleen, while Chen Pi and Da Fu Pi restore Qi circulation in the Middle Burner to reactivate the Spleen's transportive function. Sang Bai Pi descends Lung Qi to reopen the water passages from above, and Sheng Jiang Pi disperses superficial water from the skin. The formula treats both the excess (accumulated water) and the underlying weakness (sluggish Spleen Qi) that allowed it to build up.

A practitioner would look for one or more of these signs

Edema

Generalized swelling of the whole body, pitting on pressure

Abdominal Distention

Fullness and bloating of the chest and abdomen

Oliguria

Reduced or difficult urination

Exertional Dyspnea

Shortness of breath or rapid breathing due to water pressing upward

Eye Fatigue

Heaviness and fatigue of the limbs

How It Addresses the Root Cause

Wu Pi Yin addresses a pattern where the Spleen's ability to transform and transport fluids has weakened, allowing Dampness to accumulate and overflow into the skin and muscles. In TCM theory, the Spleen is the central organ responsible for managing body fluids. When it becomes sluggish, water is no longer properly distributed and instead pools beneath the skin, producing generalized puffiness and swelling that is most noticeable in the face, limbs, and abdomen.

This stagnant water also obstructs the smooth flow of Qi. When Qi cannot circulate, the abdomen and chest feel full and distended, urination becomes scanty and difficult, and breathing may become labored. There is a vicious cycle: Dampness blocks Qi movement, and stagnant Qi further impairs the Spleen's ability to clear Dampness. The Lungs, which in TCM govern the downward regulation of the water pathways, are also affected. When Lung Qi fails to descend properly, fluid distribution to the Kidneys and Bladder is disrupted, compounding the water retention.

The formula intervenes at multiple points in this cycle. It gently strengthens the Spleen to restore fluid transportation, moves Qi to break through stagnation, descends Lung Qi to reopen the water pathways, and directly promotes urination to drain the accumulated fluid from the skin level. Importantly, this is a mild formula suited to relatively superficial, mild-to-moderate edema where the underlying deficiency is not severe.

Formula Properties

Temperature

Slightly Warm

Taste Profile

Predominantly bland and pungent (acrid). Bland to leach out Dampness through urination, pungent to move Qi and disperse water stagnation.

Target Organs
Spleen Lungs Kidneys Stomach
Channels Entered
Spleen Stomach Lung Kidney

Formula Origin

Huá Shì Zhōng Zàng Jīng (華氏中藏經, Hua's Central Treasury Classic)

This is just partial information on the formula's TCM properties. More detailed information is available on the formula's dedicated page

Ingredients in Wu Pi Yin

Detailed information about each herb in Wu Pi Yin and their roles

Fu Ling Pi
Fu Ling Pi

Poria peel

Dosage: 15 - 30g

Temperature Neutral
Taste Sweet (甘 gān), Bland (淡 dàn)
Organ Affinity Lungs, Spleen, Kidneys
Parts Used Bark (皮 pí / 树皮 shù pí)
Role in Wu Pi Yin

The chief water-draining herb. Fu Ling Pi promotes urination and leaches out dampness while also supporting the Spleen's ability to transport and transform fluids. Given at the highest dosage in the formula, it directly addresses the core problem of water accumulation.

Sang Bai Pi
Sang Bai Pi

Mulberry root bark

Dosage: 9 - 12g

Temperature Cold
Taste Sweet (甘 gān)
Organ Affinity Lungs, Spleen
Parts Used Bark (皮 pí / 树皮 shù pí)
Role in Wu Pi Yin

Descends Lung Qi and opens the water passages from above. The Lungs are considered the 'upper source of water' in TCM, and when Lung Qi descends properly, it helps regulate the water passages and direct fluids downward to the Bladder for excretion. Sang Bai Pi supports Fu Ling Pi's diuretic action by addressing the upper part of the fluid regulation system.

Da Fu Pi
Da Fu Pi

Areca peel

Dosage: 9 - 12g

Temperature Slightly Warm
Taste Acrid / Pungent (辛 xīn)
Organ Affinity Spleen, Stomach, Large Intestine, Small Intestine
Parts Used Peel / Rind (皮 pí / 果皮 guǒ pí)
Role in Wu Pi Yin

Moves Qi in the middle and lower body, relieves abdominal distension, and promotes the downward movement of water. Since Qi stagnation and water retention often occur together, Da Fu Pi's Qi-moving action helps break up the fluid accumulation, particularly in the abdomen.

Chen Pi
Chen Pi

Tangerine peel

Dosage: 9 - 12g

Temperature Warm
Taste Acrid / Pungent (辛 xīn), Bitter (苦 kǔ)
Organ Affinity Lungs, Spleen
Parts Used Peel / Rind (皮 pí / 果皮 guǒ pí)
Role in Wu Pi Yin

Regulates Qi in the Middle Burner, strengthens the Spleen's transportive function, and dries dampness. Chen Pi works together with Da Fu Pi to restore the smooth flow of Qi, based on the principle that 'when Qi moves freely, fluids follow.' It also supports the Spleen to prevent further fluid accumulation.

Sheng Jiang Pi
Sheng Jiang Pi

Fresh ginger peel

Dosage: 6 - 9g

Temperature Cool
Taste Acrid / Pungent (辛 xīn)
Organ Affinity Spleen, Lungs
Parts Used Bark (皮 pí / 树皮 shù pí)
Role in Wu Pi Yin

Gently disperses water from the skin and superficial layers of the body. While the other herbs drain dampness downward through urination, Sheng Jiang Pi works at the body's surface to resolve superficial edema. It directs the formula's action outward to the skin level, consistent with the formula's 'use peels to treat peel-level disease' strategy.

Usage & Safety

How to use this formula and important safety information

Important Medical Disclaimer

The information provided here is for educational purposes only and is not intended as medical advice or to replace consultation with a qualified healthcare professional. This formula is a dietary supplement and has not been evaluated by the FDA. It is not intended to diagnose, treat, cure, or prevent any disease.

Always consult with a qualified healthcare provider, particularly if you are pregnant, nursing, have a medical condition, or are taking other medications. Discontinue use and consult your healthcare provider if you experience any adverse reactions.

Recommended Dosage

Instructions for safe storage and consumption

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Best Time to Take

Taken warm, twice daily (morning and afternoon), between meals. The classical instruction is 'regardless of time' (不拘时), meaning it is not strictly meal-dependent, but taking it away from meals optimizes absorption.

Typical Duration

Short-term use: typically 1 to 2 weeks for acute edema, reassessed by a practitioner. Not recommended for prolonged use without modification due to its fluid-draining nature.

Dietary Advice

The original text specifies: avoid cold and raw foods, greasy or oily foods, and hard-to-digest items (忌生冷油腻硬物). Cold and raw foods impair Spleen function and worsen Dampness, directly counteracting what this formula is trying to achieve. Foods that are damp-producing should also be minimized, including excessive dairy, refined sugar, heavy fried foods, and alcohol. Favor warm, lightly cooked meals that support the Spleen, such as congee (rice porridge), cooked root vegetables, barley (Yi Yi Ren) soup, and winter melon. Adequate water intake is important but should not be excessive while active edema is being treated.

Special Populations

Pregnancy

Wu Pi Yin is traditionally considered usable during pregnancy and has in fact been classically indicated for pregnancy-related edema (妊娠水肿). None of the five herbs in the formula are known abortifacients or uterine stimulants. Da Fu Pi (Areca Peel) has a mild Qi-moving action that is far gentler than its parent substance Bing Lang (Areca Nut), which would be contraindicated. However, as a fluid-draining formula, it should only be used during pregnancy under the guidance of a qualified practitioner to ensure the edema is appropriately diagnosed as Spleen deficiency type and that dosage and duration are carefully monitored. Overuse of any diuretic formula risks depleting fluids needed to nourish the fetus.

Breastfeeding

Wu Pi Yin is generally considered compatible with breastfeeding. The herbs in this formula are mild in nature and are not known to contain compounds that transfer into breast milk in harmful concentrations. However, because the formula promotes urination and drains fluids, excessive or prolonged use could theoretically reduce overall fluid volume, which might affect milk production in some individuals. Breastfeeding mothers should use this formula only as needed for edema, stay well hydrated, and consult a qualified practitioner for appropriate dosage and duration.

Pediatric Use

Wu Pi Yin can be used in children for appropriate presentations of edema with Spleen deficiency, but dosage must be significantly reduced based on age and body weight. A general guideline is one-third to one-half the adult dose for children aged 6 to 12, and one-quarter for children under 6. Because children's Spleen and Stomach systems are inherently delicate, the Qi-moving and fluid-draining actions of this formula may be too strong for very young or constitutionally weak children. Duration should be kept short. This formula is not typically a first-line choice in pediatrics and a practitioner should always be consulted.

Drug Interactions

Pharmaceutical diuretics (furosemide, hydrochlorothiazide, spironolactone): Wu Pi Yin promotes urination through multiple mechanisms. When combined with Western diuretic medications, there is a risk of excessive fluid loss, dehydration, and electrolyte imbalances (particularly low potassium and sodium). Close monitoring is advised if co-administration is necessary.

Antihypertensive medications: The fluid-reducing effect of the formula may enhance the blood-pressure-lowering effect of antihypertensives, potentially leading to hypotension. Blood pressure should be monitored.

Da Fu Pi (Areca Peel) contains trace amounts of arecoline-related alkaloids. While the peel contains far less than the areca nut itself, theoretically these alkaloids could interact with cholinergic drugs, anticholinergics, or drugs metabolized by similar pathways. The clinical significance at typical decoction doses is considered low, but awareness is warranted.

Contraindications

Avoid

Yin deficiency with fluid depletion and no Dampness. This formula drains fluids and can further deplete Yin in those who are already fluid-deficient.

Avoid

Qi and Blood deficiency without Dampness. The formula's draining and Qi-moving actions can further exhaust someone who is already weak. As classical sources note, Da Fu Pi (Areca Peel) 'can deplete true Qi' and is contraindicated for deficiency-type distension.

Avoid

Severe Kidney failure or electrolyte imbalance. The diuretic action of this formula may worsen fluid and electrolyte disturbances in patients with severely impaired kidney function.

Caution

Damp-Heat patterns. The formula is designed for Spleen deficiency with cold-Dampness. In cases of marked Heat, it may be insufficient or inappropriate without modification.

Caution

Prolonged use without reassessment. As a draining formula, extended use can gradually injure Qi and Yin. Duration should be limited and regularly reviewed.

Cautions & Warnings

Wu Pi Yin is typically safe for most individuals, but it can lead to side effects in some cases. Pregnant, nursing, or postpartum women, as well as those with liver conditions, should use this formula cautiously and preferably under professional supervision.

As with any Chinese herbal remedy, it is advisable to seek guidance from a qualified Traditional Chinese Medicine (TCM) practitioner before beginning treatment with this formula.

Product Details

Manufacturing, supplier, and product specifications

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Granules

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Treasure of the East

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