Formula

Shi Quan Da Bu Tang

Ginseng & Dang Gui Ten Combination | 十全大补汤

Also known as:

All-Inclusive Great Tonifying Decoction , All-Inclusive Tonifying Decoction

Properties

Qi and Blood tonifying formulas · Warm

Key Ingredients

Ren Shen, Shu Di Huang

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

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About This Formula

Traditional Chinese Medicine background and properties

Formula Description

A classical warming and tonifying formula used to rebuild both Qi and Blood in people suffering from deep exhaustion, pallor, cold limbs, poor appetite, and general weakness. It combines the Qi-boosting herbs of Si Jun Zi Tang with the Blood-nourishing herbs of Si Wu Tang, plus Huang Qi and Rou Gui for extra warming power. Commonly used after prolonged illness, surgery, or cancer treatment to restore vitality.

Formula Category

Main Actions

  • Tonifies Qi and Generates Blood
  • Strengthens the Spleen and Lungs
  • Nourishes Blood and regulates menstruation
  • Secures the Exterior
  • Promotes Tissue Regeneration and Heals Sores

TCM Patterns

In TCM, symptoms don't appear randomly — they cluster into recognizable patterns of disharmony that reveal what's out of balance in the body. Shi Quan Da Bu Tang is traditionally associated with these specific patterns.

The following describes this formula's classification within Traditional Chinese Medicine theory and is provided for educational purposes only.

Why Shi Quan Da Bu Tang addresses this pattern

Qi and Blood Deficiency is the core pattern this formula was designed to treat. When both Qi and Blood are depleted, the body loses its ability to warm the limbs, nourish the complexion, maintain mental alertness, and sustain physical strength. The Spleen (the source of Qi and Blood production) is weakened, leading to poor appetite and fatigue, while the Heart and Liver (which govern Blood and spirit) cannot be properly nourished, causing palpitations, dizziness, and emotional fragility.

Shi Quan Da Bu Tang addresses this by simultaneously rebuilding Qi through Ren Shen, Huang Qi, Bai Zhu, and Fu Ling, and replenishing Blood through Shu Di Huang, Dang Gui, Bai Shao, and Chuan Xiong. The addition of Rou Gui adds warming support, which is essential because severe Qi and Blood deficiency often leads to internal Cold.

A practitioner would look for one or more of these signs

Eye Fatigue

Deep, persistent tiredness worsened by exertion

Dull Pale Complexion

Sallow or yellowish pale face

Dizziness

Lightheadedness, especially on standing

Palpitations

Heart palpitations with a sensation of anxiety

Shortness Of Breath

Breathlessness on mild activity

Poor Appetite

Reduced desire to eat

Cold Limbs

Hands and feet that are consistently cold

Spontaneous Sweat

Sweating without exertion, especially daytime

How It Addresses the Root Cause

This formula addresses a pattern of dual deficiency of both Qi and Blood (气血两虚), often with an underlying tendency toward internal Cold. In TCM theory, Qi and Blood are deeply interdependent: Qi is the motive force that generates and circulates Blood, while Blood is the material basis that nourishes and anchors Qi. When a person suffers from prolonged illness, excessive blood loss (such as heavy menstruation or surgical bleeding), chronic overwork, or emotional strain, both Qi and Blood can become depleted simultaneously. The Spleen, which is the central organ responsible for generating both Qi and Blood from food, becomes weakened and can no longer produce sufficient nourishment for the body.

As Qi and Blood decline together, a cascade of symptoms develops. Without enough Blood, the complexion becomes sallow and pale, there is dizziness, blurred vision, and palpitations because the Heart and brain lack nourishment. Without enough Qi, the person feels constantly fatigued, short of breath, and has a weak voice and poor appetite. Because Qi also controls the body's warming function and the defensive exterior, deficient patients often feel cold in the limbs, sweat spontaneously or at night, and are more vulnerable to illness. In severe or chronic cases, the Kidney Yang, the deepest source of warmth in the body, also weakens, leading to low back and knee soreness, cold extremities, and reduced vitality.

The formula works by rebuilding both Qi and Blood from their respective sources (the Spleen for Qi, the Liver and Kidneys for Blood) while adding a warming component that gently kindles the body's internal fire. This restores the generative cycle: a stronger Spleen produces more Qi and Blood, warmer Yang ensures that these substances circulate properly, and with adequate Qi and Blood flowing again, the organs resume their normal functions and the body can heal wounds, regulate menstruation, and resist disease.

Formula Properties

Temperature

Warm

Taste Profile

Predominantly sweet and warm, with mild bitter and pungent notes. The sweet taste tonifies and nourishes Qi and Blood, the pungent taste (from Rou Gui and Chuan Xiong) promotes circulation, and the mild bitterness (from Bai Zhu) supports Spleen drying.

Target Organs
Spleen Heart Liver Lungs Kidneys
Channels Entered
Spleen Heart Liver Lung Kidney

Formula Origin

Tài Píng Huì Mín Hé Jì Jú Fāng (太平惠民和剂局方)

This is just partial information on the formula's TCM properties. More detailed information is available on the formula's dedicated page

Ingredients in Shi Quan Da Bu Tang

Detailed information about each herb in Shi Quan Da Bu Tang and their roles

Kings
Deputies
Assistants
Envoys
Ren Shen
Ren Shen

Ginseng root

Dosage: 6 - 10g

Temperature Slightly Warm
Taste Sweet (甘 gān), Bitter (苦 kǔ)
Organ Affinity Spleen, Lungs, Heart, Kidneys
Parts Used Root (根 gēn)
Role in Shi Quan Da Bu Tang

Powerfully tonifies the primal Qi, strengthens the Spleen and Lung, and serves as the chief Qi-supplementing herb in the formula. It addresses the root deficiency that underlies the entire pattern.

Shu Di Huang
Shu Di Huang

Prepared Rehmannia root

Dosage: 9 - 12g

Temperature Slightly Warm
Taste Sweet (甘 gān)
Organ Affinity Liver, Kidneys
Parts Used Tuber (块茎 kuài jīng / 块根 kuài gēn)
Role in Shi Quan Da Bu Tang

The primary Blood-nourishing herb. Prepared Rehmannia richly nourishes the Blood and Yin of the Liver and Kidney, addressing the Blood deficiency aspect of the pattern.

Bai Zhu
Bai Zhu

White Atractylodes rhizome

Dosage: 9 - 10g

Temperature Warm
Taste Bitter (苦 kǔ), Sweet (甘 gān)
Organ Affinity Spleen, Stomach
Parts Used Rhizome (根茎 gēn jīng)
Role in Shi Quan Da Bu Tang

Strengthens the Spleen and dries Dampness, assisting Ren Shen in tonifying Qi and ensuring the digestive system can generate Qi and Blood from food.

Dang Gui
Dang Gui

Chinese Angelica root

Dosage: 9 - 10g

Temperature Warm
Taste Sweet (甘 gān), Acrid / Pungent (辛 xīn)
Organ Affinity Liver, Heart, Spleen
Parts Used Root (根 gēn)
Role in Shi Quan Da Bu Tang

Nourishes and invigorates the Blood, entering the Liver and Heart channels. Assists Shu Di Huang in replenishing Blood while also gently promoting Blood circulation to prevent stagnation from the rich tonics.

Huang Qi
Huang Qi

Astragalus root

Dosage: 9 - 12g

Temperature Slightly Warm
Taste Sweet (甘 gān)
Organ Affinity Spleen, Lungs
Parts Used Root (根 gēn)
Role in Shi Quan Da Bu Tang

Strongly tonifies Qi and raises Yang, reinforcing the exterior and stabilizing the Wei Qi to address spontaneous sweating. Works alongside Ren Shen to greatly amplify the Qi-tonifying power of the formula.

Bai Shao
Bai Shao

White peony root

Dosage: 9 - 10g

Temperature Slightly Cool
Taste Bitter (苦 kǔ), Sour (酸 suān)
Organ Affinity Liver, Spleen
Parts Used Root (根 gēn)
Role in Shi Quan Da Bu Tang

Nourishes the Blood and preserves Yin, softens the Liver and alleviates pain. Complements the Blood-tonifying action of Shu Di Huang and Dang Gui while helping to consolidate Yin fluids.

Fu Ling
Fu Ling

Poria

Dosage: 9 - 10g

Temperature Neutral
Taste Sweet (甘 gān), Bland (淡 dàn)
Organ Affinity Heart, Lungs, Spleen, Kidneys
Parts Used Fungus / Mushroom (菌类 jūn lèi)
Role in Shi Quan Da Bu Tang

Strengthens the Spleen and promotes water metabolism. Prevents the rich, cloying Blood tonics from causing Dampness, and assists Ren Shen and Bai Zhu in supporting the digestive transformation.

Chuan Xiong
Chuan Xiong

Sichuan lovage rhizome

Dosage: 5 - 6g

Temperature Warm
Taste Acrid / Pungent (辛 xīn)
Organ Affinity Liver, Gallbladder, Pericardium
Parts Used Rhizome (根茎 gēn jīng)
Role in Shi Quan Da Bu Tang

Invigorates the Blood and promotes the movement of Qi. Its pungent, moving nature prevents the heavy tonifying herbs from creating stagnation, ensuring the new Blood and Qi circulate freely.

Rou Gui
Rou Gui

Cinnamon bark

Dosage: 2 - 3g

Temperature Hot
Taste Acrid / Pungent (辛 xīn), Sweet (甘 gān)
Organ Affinity Heart, Liver, Spleen, Kidneys
Parts Used Bark (皮 pí / 树皮 shù pí)
Role in Shi Quan Da Bu Tang

Warms the Yang, dispels interior Cold, and warms the channels to promote Blood circulation. Its hot nature activates the warming aspect of the formula, embodying the principle that Yang warmth generates Yin substance.

Gan Cao
Gan Cao

Licorice root

Dosage: 3 - 5g

Temperature Neutral
Taste Sweet (甘 gān)
Organ Affinity Heart, Lungs, Spleen, Stomach
Parts Used Root (根 gēn)
Role in Shi Quan Da Bu Tang

Honey-prepared licorice tonifies the Spleen Qi, harmonizes all the other herbs in the formula, and moderates the drying or draining properties of certain ingredients.

Modern Research (4 studies)

  • Effectiveness of 3-Week Intervention of Shi Quan Da Bu Tang for Alleviating Hematotoxicity Among Patients With Breast Carcinoma Receiving Chemotherapy (Retrospective Cohort Study, 2013)
  • Shi-quan-da-bu-tang (SQT): A Potent Chinese Biological Response Modifier in Cancer Immunotherapy, Potentiation and Detoxification of Anticancer Drugs (Preclinical/Clinical Review, 1992)
See all research on the formula page

Usage & Safety

How to use this formula and important safety information

Important Medical Disclaimer

The information provided here is for educational purposes only and is not intended as medical advice or to replace consultation with a qualified healthcare professional. This formula is a dietary supplement and has not been evaluated by the FDA. It is not intended to diagnose, treat, cure, or prevent any disease.

Always consult with a qualified healthcare provider, particularly if you are pregnant, nursing, have a medical condition, or are taking other medications. Discontinue use and consult your healthcare provider if you experience any adverse reactions.

Recommended Dosage

Instructions for safe storage and consumption

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Best Time to Take

30 minutes to 1 hour before meals, twice daily (morning and early evening), taken warm. The original text states 'take warm, without regard to time' (不拘时候温服).

Typical Duration

Typically taken for 2-8 weeks as a course of treatment, then reassessed. For chronic deficiency conditions, it may be taken intermittently over several months with periodic breaks.

Dietary Advice

While taking this formula, favor warm, easily digestible foods that support the Spleen and Stomach: cooked grains (rice, millet, oats), soups, stews, root vegetables, chicken, lamb, dates, and longan fruit. Avoid cold and raw foods (salads, ice cream, cold drinks, raw fish) as these can obstruct the Spleen's warming and transforming function and reduce the formula's effectiveness. Also avoid greasy, heavy, or overly rich foods, which can generate Dampness and Phlegm that counteract the tonifying herbs. Limit spicy, hot, or excessively drying foods (chili, alcohol, fried foods) as the formula is already warming. Green tea and strongly cooling foods (watermelon, bitter melon, mung beans) are best avoided in large amounts as they may undermine the warming therapeutic direction.

Modern Usage

Shi Quan Da Bu Tang is a renowned classical formula celebrated for its warming tonic properties.

In TCM, it is used to tonify Qi, Blood, and Yang, offering a more warming effect compared to Ba Zhen Tang. TCM practitioners frequently recommend this formula for individuals experiencing a variety of conditions stemming from Qi, Blood, and Yang Deficiencies. These conditions may include fatigue, decreased appetite, lower limb weakness, shortness of breath, pale complexion, hair loss, and other related symptoms.

Special Populations

Pregnancy

Generally considered safe with appropriate supervision, but use with caution. The formula itself is not abortifacient and was historically used to support depleted constitutions in women. However, Rou Gui (Cinnamon Bark) has Blood-moving and warming properties that theoretically could stimulate uterine activity, and Chuan Xiong (Ligusticum) is a Blood-activating herb. Dang Gui (Angelica sinensis) also promotes blood circulation. While these herbs are used at moderate doses within this formula's tonifying context, pregnant women should only take Shi Quan Da Bu Tang under the guidance of a qualified practitioner who can assess the individual situation. It should not be used during the first trimester without clear clinical need. Toxicology studies on the Japanese Kampo version (Juzen-taiho-to) have not revealed significant teratogenic toxicity at normal doses.

Breastfeeding

Generally considered compatible with breastfeeding when used under practitioner supervision. The formula's constituent herbs are traditionally used in the postpartum period to help replenish Qi and Blood after childbirth and may support milk production by strengthening the Spleen's ability to generate Blood (which is the material basis for breast milk in TCM). Ren Shen (Ginseng) and Huang Qi are commonly used in postpartum recovery formulas. However, the warming nature of the formula could theoretically make breast milk warmer in quality, which may not suit infants showing signs of Heat (restlessness, skin rashes). There are no well-documented adverse effects on nursing infants. Use at standard doses and monitor the infant for any signs of irritability or digestive upset. Children, pregnant women, and breastfeeding women should use this formula under qualified practitioner guidance.

Pediatric Use

Shi Quan Da Bu Tang can be used in children but requires significant dose reduction based on age and body weight. A common guideline is to use approximately one-quarter to one-third of the adult dose for children aged 6-12 years, and one-sixth or less for children under 6 years. Children's constitutions tend to run warmer and their Spleen function is still developing, so the warming and cloying nature of this formula can easily cause digestive upset, restlessness, or signs of Heat (nosebleeds, mouth sores). It is most appropriate for children who clearly show Qi and Blood deficiency with Cold signs, such as those recovering from prolonged illness, chronic anemia, or failure to thrive. It is not suitable as a general children's tonic. The formula should only be administered to children under the guidance of a qualified practitioner, and the dose of Rou Gui (Cinnamon Bark) in particular should be kept small.

Drug Interactions

Anticoagulants and antiplatelet drugs (e.g. warfarin, heparin, aspirin, clopidogrel): Dang Gui (Angelica sinensis) and Chuan Xiong (Ligusticum) have documented blood-activating properties. Combined use may increase bleeding risk. Patients on anticoagulant therapy should be monitored for changes in INR or signs of unusual bleeding.

Antihypertensives: Ren Shen (Ginseng) and Huang Qi (Astragalus) can raise blood pressure in some individuals, potentially counteracting the effects of antihypertensive medications. Blood pressure should be monitored when co-administering.

Hypoglycemic agents (insulin, metformin, sulfonylureas): Ren Shen (Ginseng) has blood sugar-lowering effects and may potentiate hypoglycemic drugs, increasing the risk of low blood sugar. Blood glucose monitoring is advisable.

Corticosteroids and immunosuppressants: Gan Cao (Glycyrrhiza/Licorice) contains glycyrrhizin, which can cause pseudoaldosteronism (potassium loss, sodium retention, edema, elevated blood pressure). This risk is increased with concurrent corticosteroid use. Glycyrrhizin may also affect the metabolism of certain corticosteroids.

Digoxin and cardiac glycosides: Gan Cao-induced hypokalemia can potentiate digoxin toxicity. Electrolyte levels should be monitored.

Diuretics: The potassium-depleting effect of Gan Cao may be worsened by concurrent thiazide or loop diuretics, increasing the risk of hypokalemia.

Contraindications

Avoid

Excess Heat or Toxic Heat patterns (e.g. high fever due to external invasion, acute infections with inflammatory signs). This heavily warming, tonifying formula would trap Heat and worsen the condition.

Avoid

Yin Deficiency with Empty Fire (阴虚火旺). The warm and drying nature of Huang Qi, Ren Shen, and especially Rou Gui can further deplete Yin fluids and fan Empty Fire, worsening symptoms like night sweats, hot flashes, and a red tongue with little coating.

Caution

Dampness, Phlegm-Dampness, or Damp-Heat accumulation. The rich, cloying herbs (Shu Di Huang, Dang Gui) can aggravate Dampness and impair Spleen transport, causing bloating, loose stools, and a greasy tongue coating.

Caution

Active bleeding due to Blood Heat. While the formula treats deficiency-type bleeding (崩漏), it should not be used if bleeding is caused by Heat forcing Blood out of the vessels, as its warming properties could intensify hemorrhage.

Caution

Patients with hypertension or prone to Liver Yang Rising. Ren Shen and Huang Qi can raise blood pressure, and the overall warm-tonifying nature may aggravate headache, dizziness, and facial flushing associated with ascending Yang.

Caution

Indigestion or food stagnation. When the Spleen and Stomach are congested with undigested food, the heavy tonifying herbs will further burden digestion. The stagnation should be resolved first before using this formula.

Cautions & Warnings

Although Shi Quan Da Bu Tang is typically safe for most individuals, it may cause side effects in some people. Pregnant women, nursing mothers, postpartum women, and those with liver disease should use Shi Quan Da Bu Tang with caution.

As with any Chinese herbal remedy, it is advisable to seek guidance from a qualified Traditional Chinese Medicine (TCM) practitioner before beginning treatment.

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Manufacturing, supplier, and product specifications

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