Formula

Qing E Wan

青娥丸

Also known as:

Qing E Wan (青娥丸, Youth-Restoring Kidney Pill)

Properties

Yang-tonifying formulas · Warm

Key Ingredients

Du Zhong

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

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$85.00 ($0.85/g)
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About This Formula*

Traditional Chinese Medicine background and properties

Formula Description*

A classical formula for strengthening the lower back and knees by warming and supporting the Kidneys. It is used for lower back pain, weak knees, and general signs of Kidney Yang decline such as cold sensitivity, fatigue, and difficulty moving, particularly in older adults or those with chronic overexertion.

Formula Category*

Main Actions*

  • Tonifies the Kidneys
  • Strengthens the Lower Back and Knees
  • Tonifies Kidney Yang
  • Strengthens the Sinews and Bones

TCM Patterns*

In TCM, symptoms don't appear randomly — they cluster into recognizable patterns of disharmony that reveal what's out of balance in the body. Qing E Wan is traditionally associated with these specific patterns.

The following describes this formula's classification within Traditional Chinese Medicine theory and is provided for educational purposes only.

Why Qing E Wan addresses this pattern

Kidney Yang deficiency is the primary pattern this formula addresses. When Kidney Yang declines, it can no longer warm and nourish the lower back (the 'mansion of the Kidneys'), the bones, and the sinews. This leads to chronic lumbar aching and weakness, cold sensations in the lower body, and difficulty with movement. Du Zhong directly strengthens the lumbar region while tonifying Liver and Kidney. Bu Gu Zhi provides deep Kidney Yang warming. Hu Tao Ren supplements Kidney Essence, and Da Suan disperses Cold and opens the channels. Together, they restore the warming and structural functions of Kidney Yang, relieving pain and restoring mobility.

A practitioner would look for one or more of these signs

Lower Back Pain

Chronic, dull aching that worsens with fatigue and improves with rest

Knee Pain

Soft, weak knees with difficulty standing or walking

Cold Sensation In Lower Body

Feeling of cold in the lumbar region and lower limbs

Eye Fatigue

General tiredness and lack of physical strength

Frequent Urination

Increased urination, especially at night

How It Addresses the Root Cause*

The Kidneys in TCM govern the bones and lumbar region. The lower back is called the "mansion of the Kidneys" (腰为肾之府), meaning its strength and vitality depend directly on the state of Kidney Qi and Yang. When Kidney Yang becomes deficient, whether from aging, constitutional weakness, excessive physical labor, or sexual overexertion, the lumbar region loses its warming support and nourishment.

Without sufficient Kidney Yang to warm and strengthen the sinews and bones of the lower back, two things happen. First, the area becomes structurally weak: the muscles, tendons, and bones lack the vital force needed to maintain strength, leading to soreness, weakness, and a dull, persistent ache in the lower back and knees. Second, the deficiency creates a vulnerability to cold: cold pathogenic factors can easily settle into the lower back because there is not enough Yang warmth to resist them, worsening the pain and stiffness.

This formula addresses the root of the problem by directly replenishing Kidney Yang and strengthening the lumbar region. By warming the Kidney fire and nourishing the sinews and bones, it restores the structural integrity and warmth that the lower back needs. The warming approach also helps dispel any cold that has lodged in the area due to the underlying deficiency.

Formula Properties*

Temperature

Warm

Taste Profile

Predominantly bitter and pungent with a sweet undertone. The bitter and pungent flavors warm the Kidneys and invigorate circulation, while the sweetness from walnut kernel gently nourishes.

Target Organs
Kidneys Liver
Channels Entered
Kidney Liver

Formula Origin

Tai Ping Hui Min He Ji Ju Fang (太平惠民和剂局方)

This is just partial information on the formula's TCM properties. More detailed information is available on the formula's dedicated page

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Product Details

Manufacturing, supplier, and product specifications

Product Type

Granules

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Supplier Information

Treasure of the East

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Ingredients in Qing E Wan

Detailed information about each herb in Qing E Wan and their roles

Kings
Deputies
Assistants
Envoys
Du Zhong
Du Zhong

Eucommia bark

Dosage: 480g (pill preparation ratio)

Temperature Warm
Taste Sweet (甘 gān)
Organ Affinity Liver, Kidneys
Parts Used Bark (皮 pí / 树皮 shù pí)
Role in Qing E Wan

Tonifies the Liver and Kidneys, strengthens the sinews and bones, and is the primary herb for treating Kidney deficiency lower back pain. Used salt-fried to direct its action downward to the Kidneys. As the largest dose in the formula, it directly addresses the core pathomechanism of Kidney weakness leading to structural decline in the lumbar region.

Bu Gu Zhi
Bu Gu Zhi

Psoralea fruit

Dosage: 240g (pill preparation ratio)

Temperature Warm
Taste Acrid / Pungent (辛 xīn), Bitter (苦 kǔ)
Organ Affinity Kidneys, Spleen
Parts Used Fruit (果 guǒ / 果实 guǒ shí)
Role in Qing E Wan

Warms Kidney Yang and consolidates Essence. Its name literally means 'bone-mending resin,' reflecting its classical reputation for strengthening bones. It powerfully reinforces Du Zhong's Kidney-warming action, adding direct Yang tonification to the formula's structural-support strategy.

Hu Tao Ren
Hu Tao Ren

Walnut kernel

Dosage: 150g (pill preparation ratio)

Temperature Warm
Taste Sweet (甘 gān)
Organ Affinity Kidneys, Lungs, Large Intestine
Parts Used Seed (种子 zhǒng zǐ / 子 zǐ / 仁 rén)
Role in Qing E Wan

Tonifies the Kidneys, warms Yang, and nourishes Essence and Blood. Its oily, rich nature moistens and supplements, adding a nourishing dimension that prevents the formula from being purely warming and drying. Also helps bind the pill formulation.

Da Huang
Da Huang

Rhubarb root and rhizome

Dosage: 120g (pill preparation ratio)

Temperature Cold
Taste Bitter (苦 kǔ)
Organ Affinity Spleen, Stomach, Large Intestine, Liver, Pericardium
Parts Used Root (根 gēn)
Role in Qing E Wan

Warms the interior, disperses Cold, unblocks stagnation, and promotes circulation through the channels. Its pungent, warming nature drives the formula's tonic herbs into the channels and sinews, helping to relieve pain by moving Qi and opening obstructions in the lumbar region.

Modern Research (4 studies)

  • Positive Effects of Qing'e Pill on Trabecular Microarchitecture and Its Mechanical Properties in Osteopenic Ovariectomised Mice (Preclinical study, 2019)
  • Qing'e Pill Inhibits Osteoblast Ferroptosis via ATM Serine/Threonine Kinase (ATM) and the PI3K/AKT Pathway in Primary Osteoporosis (Preclinical network pharmacology and animal study, 2022)
See all research on the formula page

Usage & Safety

How to use this formula and important safety information

Important Medical Disclaimer

The information provided here is for educational purposes only and is not intended as medical advice or to replace consultation with a qualified healthcare professional. This formula is a dietary supplement and has not been evaluated by the FDA. It is not intended to diagnose, treat, cure, or prevent any disease.

Always consult with a qualified healthcare provider, particularly if you are pregnant, nursing, have a medical condition, or are taking other medications. Discontinue use and consult your healthcare provider if you experience any adverse reactions.

Recommended Dosage

Instructions for safe storage and consumption

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Best Time to Take

Before meals, ideally in the morning and evening. Traditionally taken with warm water or, in classical preparation, with warm rice wine on an empty stomach to enhance absorption and direct the formula to the Kidneys.

Typical Duration

Chronic use: typically taken for 4-12 weeks as a course, then reassessed by a practitioner. May be taken in repeated courses for chronic Kidney deficiency conditions.

Dietary Advice

Favor warm, cooked foods that support the Kidneys: black beans, walnuts, dark sesame, lamb, bone broth, and warm soups. Avoid cold and raw foods such as salads, iced drinks, and excessive fruit, which can further weaken Yang and hinder the formula's warming action. Reduce intake of excessively greasy or phlegm-producing foods. Moderate salt intake is traditionally considered beneficial for guiding the formula's action toward the Kidneys.

Special Populations

Pregnancy

Use with caution during pregnancy. Bu Gu Zhi (Psoralea fruit) is a strongly warming Kidney Yang tonic that contains psoralen and related compounds with potential hormonal activity. While Du Zhong (Eucommia bark) is traditionally considered to calm a restless fetus, the overall warming and Yang-tonifying nature of the formula may not be appropriate for all pregnant patients. A qualified practitioner should assess whether the formula is suitable on a case-by-case basis. Not recommended for self-prescription during pregnancy.

Breastfeeding

No specific contraindication is established for breastfeeding. However, Bu Gu Zhi (Psoralea fruit) contains psoralen and isopsoralen, bioactive compounds whose transfer into breast milk has not been well studied. The formula's warm, Yang-tonifying nature is generally considered safe for postpartum recovery when Kidney Yang deficiency is present, but caution is advised. Consult a qualified practitioner before use during breastfeeding.

Pediatric Use

Qing E Wan is not a typical pediatric formula. It is designed for adults with Kidney Yang deficiency, a pattern that is far more common in middle-aged and elderly patients. Children and adolescents rarely require this type of Yang-warming Kidney tonic. The strong Yang-tonifying herbs (particularly Bu Gu Zhi) are generally not appropriate for developing bodies. Use in children should only be considered in exceptional cases under the guidance of a qualified practitioner experienced in pediatric TCM, with significant dose reduction.

Cautions & Warnings

Qing E Wan is typically safe for most individuals, but it can lead to side effects in some cases. Pregnant, nursing, or postpartum women, as well as those with liver conditions, should use this formula cautiously and preferably under professional supervision.

As with any Chinese herbal remedy, it is advisable to seek guidance from a qualified Traditional Chinese Medicine (TCM) practitioner before beginning treatment with Qing E Wan.