Formula

Mai Men Dong Tang

Ophiopogon Combination | 麦门冬汤

Also known as:

Ophiopogon formula , Dwarf lilyturf Decoction , Ophiopogonis Decoction

Properties

Dryness-treating formulas · Slightly Cool

Key Ingredients

Tian Men Dong

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

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About This Formula

Traditional Chinese Medicine background and properties

Formula Description

A classical formula for nourishing the lungs and stomach, used for persistent dry cough, throat dryness, shortness of breath, or nausea caused by depleted fluids in the respiratory and digestive systems. It works by replenishing moisture in the body while gently directing upward-rising Qi back downward.

Formula Category

Main Actions

  • Nourishes Lung and Stomach Yin
  • Clears Deficiency Heat
  • Descends Qi
  • Generates Fluids
  • Moistens Dryness
  • Descends Lung Qi and Stops Cough

TCM Patterns

In TCM, symptoms don't appear randomly — they cluster into recognizable patterns of disharmony that reveal what's out of balance in the body. Mai Men Dong Tang is traditionally associated with these specific patterns.

The following describes this formula's classification within Traditional Chinese Medicine theory and is provided for educational purposes only.

Why Mai Men Dong Tang addresses this pattern

When the Stomach's fluids are depleted, it can no longer send moisture upward to nourish the Lungs. The Lungs dry out, lose their natural descending function, and Qi rebels upward, producing cough, wheezing, and spitting of thin frothy sputum. The throat and mouth become parched because fluids cannot rise to moisten them. This formula addresses the root by heavily nourishing Lung and Stomach Yin with Mai Men Dong, while supporting the Stomach's fluid-generating capacity with Ren Shen, Jing Mi, Da Zao, and Gan Cao. Ban Xia descends the rebellious Qi that causes coughing and vomiting. The overall strategy restores the Lung-Stomach fluid axis from its source.

A practitioner would look for one or more of these signs

Chronic Coughing

Persistent dry cough or cough with thin frothy sputum

Dry Throat

Dry mouth and throat, especially worse at night

Shortness Of Breath

Shortness of breath, especially on exertion

Dry Mouth

Persistent thirst and dryness

Night Sweats

Warm palms and soles (five-palm heat)

Hoarseness

Hoarse or weak voice

How It Addresses the Root Cause

The condition this formula addresses begins in the Stomach, not the Lungs. In TCM, the Stomach is the body's primary source of fluids: it receives food and drink, extracts nourishment, and sends precious fluids upward to moisten the Lungs. When the Stomach's Yin (its cooling, moistening reserves) becomes depleted, whether through chronic illness, febrile disease that consumed fluids, or overwork, this upward supply of moisture dries up. The Lungs, which depend on the Stomach as a mother depends on Earth nurturing Metal (the "Earth generates Metal" or 培土生金 principle), are left parched.

Without adequate moisture, the Lungs cannot perform their normal descending and distributing function. Qi that should flow smoothly downward instead rebels upward, producing coughing, wheezing, and a sense of obstruction in the throat. The dryness also generates a paradoxical form of phlegm: because fluids are not being properly distributed, they congeal into sticky, turbid sputum or frothy saliva that is coughed up repeatedly. The more this sputum is expectorated, the more fluid is lost, creating a vicious cycle. Meanwhile, the Yin deficiency allows deficiency Heat (a low-grade smoldering warmth, not robust fever) to develop unchecked. This Heat further scorches the remaining fluids, producing dry mouth, dry throat, warm palms and soles, a red tongue with little coating, and a weak, rapid pulse. If the Stomach aspect predominates, nausea, hiccups, poor appetite, and vomiting may be the chief complaints instead.

The key insight of this formula is that treating the cough or the phlegm directly would miss the root cause. Instead, the strategy is to replenish the Stomach's fluid reserves so that moisture can once again rise naturally to nourish the Lungs, while simultaneously redirecting the rebellious Qi downward.

Formula Properties

Temperature

Slightly Cool

Taste Profile

Predominantly sweet and mildly cool, with a slight acrid accent from the small dose of Ban Xia. The sweetness nourishes Yin, generates fluids, and tonifies the Middle Burner, while the subtle pungency prevents cloying stagnation and promotes Qi descent.

Target Organs
Lungs Stomach Spleen
Channels Entered
Lung Stomach Spleen Heart

Formula Origin

Jin Gui Yao Lue (金匮要略) by Zhang Zhongjing

This is just partial information on the formula's TCM properties. More detailed information is available on the formula's dedicated page

Ingredients in Mai Men Dong Tang

Detailed information about each herb in Mai Men Dong Tang and their roles

Kings
Deputies
Assistants
Envoys
Tian Men Dong
Tian Men Dong

Asparagus tuber

Dosage: 42 - 70g

Temperature Cold
Taste Sweet (甘 gān), Bitter (苦 kǔ)
Organ Affinity Lungs, Kidneys
Parts Used Tuber (块茎 kuài jīng / 块根 kuài gēn)
Role in Mai Men Dong Tang

Used in a large dose as the principal herb, Mai Men Dong is sweet and cold. It nourishes Yin of both the Lung and Stomach, clears deficiency Heat, generates fluids, and moistens dryness. Its heavy dosage reflects the severity of Yin depletion that underlies this pattern.

Ban Xia
Ban Xia

Pinellia rhizome

Dosage: 6 - 9g

Temperature Warm
Taste Acrid / Pungent (辛 xīn)
Organ Affinity Spleen, Stomach, Lungs
Parts Used Tuber (块茎 kuài jīng / 块根 kuài gēn)
Role in Mai Men Dong Tang

Though warm and drying by nature, Ban Xia is used in a deliberately small dose to descend rebellious Qi, resolve phlegm, and stop coughing. Paired with the large amount of Mai Men Dong, its drying properties are restrained while its descending action is preserved. This pairing exemplifies the classical principle of using opposites together for synergistic effect (相反相成).

Ren Shen
Ren Shen

Ginseng root

Dosage: 6 - 9g

Temperature Slightly Warm
Taste Sweet (甘 gān), Bitter (苦 kǔ)
Organ Affinity Spleen, Lungs, Heart, Kidneys
Parts Used Root (根 gēn)
Role in Mai Men Dong Tang

Tonifies Qi and generates fluids. Working with the Stomach-nourishing herbs, it strengthens the Spleen and Stomach's ability to produce and transport fluids upward to moisten the Lungs, embodying the 'nourishing Earth to generate Metal' (培土生金) strategy.

Jing Mi
Jing Mi

Non-glutinous rice

Dosage: 3 - 6g

Temperature Neutral
Taste Sweet (甘 gān)
Organ Affinity Spleen, Stomach, Lungs
Parts Used Seed (种子 zhǒng zǐ / 子 zǐ / 仁 rén)
Role in Mai Men Dong Tang

Nourishes the Stomach, protects Stomach Qi, and assists in the production of fluids. Supports the strategy of strengthening the digestive system as the source of moisture for the Lungs.

Da Zao
Da Zao

Jujube fruit

Dosage: 4 pieces (approximately 12g)

Temperature Warm
Taste Sweet (甘 gān)
Organ Affinity Spleen, Stomach, Heart
Parts Used Fruit (果 guǒ / 果实 guǒ shí)
Role in Mai Men Dong Tang

Tonifies Qi, nourishes the Stomach, and generates fluids. Together with Ren Shen, Gan Cao, and Jing Mi, it supports the middle Qi so that the Stomach can produce adequate fluids to nourish the Lungs.

Gan Cao
Gan Cao

Licorice root

Dosage: 3 - 6g

Temperature Neutral
Taste Sweet (甘 gān)
Organ Affinity Heart, Lungs, Spleen, Stomach
Parts Used Root (根 gēn)
Role in Mai Men Dong Tang

Moistens the Lungs, soothes the throat, tonifies the middle Qi, and harmonises all the herbs in the formula. Serves both as an assistant to support the Stomach and as an envoy to harmonise the prescription.

Modern Research (5 studies)

  • A Chinese classical prescription Maimendong decoction in treatment of pulmonary fibrosis: an overview (Narrative Review, 2024)
  • Modified Maimendong decoction in the treatment of patients with idiopathic pulmonary fibrosis: Study protocol for a randomized controlled trial (RCT Protocol, 2020)
See all research on the formula page

Usage & Safety

How to use this formula and important safety information

Important Medical Disclaimer

The information provided here is for educational purposes only and is not intended as medical advice or to replace consultation with a qualified healthcare professional. This formula is a dietary supplement and has not been evaluated by the FDA. It is not intended to diagnose, treat, cure, or prevent any disease.

Always consult with a qualified healthcare provider, particularly if you are pregnant, nursing, have a medical condition, or are taking other medications. Discontinue use and consult your healthcare provider if you experience any adverse reactions.

Recommended Dosage

Instructions for safe storage and consumption

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Best Time to Take

30 minutes after meals, 2-3 times daily. The original text specifies 'three times during the day and once at night' (日三夜一服), reflecting a frequent dosing strategy to maintain consistent nourishment of depleted fluids.

Typical Duration

Typically prescribed for 1-4 weeks for acute dry cough or throat conditions; may be extended to 4-8 weeks for chronic conditions like Lung atrophy or chronic bronchitis, with regular reassessment by a practitioner.

Dietary Advice

While taking this formula, favor foods that nourish Yin and moisten dryness: pears, white fungus (tremella/yin er), lily bulb (bai he), lotus seed, congee, honey, sesame, and tofu. Drink adequate warm fluids throughout the day. Avoid foods that are spicy, fried, greasy, or overly warming (such as chili peppers, lamb, ginger in excess, alcohol, and strong coffee), as these can further deplete Yin and generate Heat. Also minimize very cold or raw foods and iced drinks, which can impair the Stomach's digestive and fluid-generating function, undermining the formula's strategy of restoring Stomach Yin to nourish the Lungs.

Modern Usage

Clinically, this formula is commonly used to treat chronic bronchitis, bronchiectasis, chronic pharyngitis, pneumoconiosis, and pulmonary tuberculosis in cases of Lung and Stomach Yin Deficiency with upward rebellious of Qi and Fire. It is also used to treat gastric and duodenal ulcers, chronic atrophic gastritis, and pregnancy-induced vomiting in cases of Stomach Yin Deficiency with Rebellious Qi and vomiting.

Special Populations

Pregnancy

Generally considered safe with appropriate practitioner guidance. None of the six herbs in this formula are classified as abortifacient or strongly contraindicated in pregnancy. Ban Xia (Pinellia) has historically been listed as a pregnancy caution herb due to its acrid, drying nature, but in this formula it is used in very small proportion relative to the moistening Mai Men Dong, and Zhang Zhongjing himself used Ban Xia in pregnancy formulas (e.g. Gan Jiang Ren Shen Ban Xia Wan for morning sickness in the Jin Gui Yao Lue). The formula has in fact been used clinically for pregnancy-related nausea and vomiting due to Stomach Yin deficiency. Nevertheless, because Ban Xia is present, use should be supervised by a qualified practitioner, and the processed form (Zhi Ban Xia) should always be used rather than raw Ban Xia.

Breastfeeding

No specific safety concerns have been established for breastfeeding. The formula's ingredients are generally mild and nourishing. Gan Cao (Licorice) in sustained high doses can theoretically affect electrolyte balance, but the moderate dose in this formula is unlikely to cause problems. Mai Men Dong and Ren Shen are not known to have adverse effects on lactation or transfer harmful substances through breast milk. However, as with all herbal formulas during breastfeeding, use should be guided by a qualified practitioner and the minimum effective course should be used.

Pediatric Use

Mai Men Dong Tang can be used in children, with appropriate dosage adjustments. General pediatric dosing follows age-based reductions: children under 3 years typically receive one-quarter to one-third of the adult dose, ages 3-7 receive one-third to one-half, and ages 7-14 receive one-half to two-thirds. Clinical case reports in the literature describe successful use in children (including a 14-year-old treated for post-meningitis sputum production). Because the formula is gentle and nourishing rather than harsh or purgative, it is generally well-tolerated in pediatric populations. The Ban Xia (Pinellia) component should always be in its processed form. For very young children, the decoction can be given in small, frequent doses rather than large single servings.

Drug Interactions

Gan Cao (Licorice root) is the most pharmacologically active herb in terms of drug interactions. Glycyrrhizin and glycyrrhetinic acid in Licorice can cause pseudoaldosteronism (sodium retention and potassium loss) with prolonged use. This creates potential interactions with:

  • Antihypertensives: Licorice may counteract blood pressure-lowering effects by promoting sodium and water retention.
  • Diuretics (especially potassium-wasting types like furosemide or thiazides): Combined potassium depletion can increase the risk of hypokalemia, which is dangerous for patients on cardiac glycosides.
  • Digoxin and cardiac glycosides: Licorice-induced hypokalemia can potentiate digoxin toxicity, increasing the risk of arrhythmias.
  • Corticosteroids: Licorice inhibits the enzyme 11-beta-hydroxysteroid dehydrogenase, potentially enhancing and prolonging corticosteroid effects.
  • Warfarin and anticoagulants: Some components of Licorice may have mild effects on coagulation pathways; monitoring is advised.

Ren Shen (Ginseng) may interact with:

  • Anticoagulants/antiplatelet agents: Ginsenosides have been reported to affect platelet aggregation. Close monitoring of INR is recommended if combined with Warfarin.
  • Hypoglycemic agents and insulin: Ginseng may have blood sugar-lowering effects, potentially enhancing the action of diabetes medications.
  • MAO inhibitors: Theoretical interaction due to Ginseng's stimulatory properties.

Patients taking any of these medications should inform their prescribing physician and herbalist to allow proper monitoring.

Contraindications

Avoid

Lung atrophy due to Deficiency Cold (虚寒肺痿). This formula is designed for Yin deficiency with Heat; using it in Cold-type Lung atrophy (characterized by thin white sputum, absence of thirst, frequent urination, and a pale tongue) would worsen the condition by introducing further cooling, moistening herbs where warming is needed.

Avoid

Dampness or Phlegm-Damp obstruction. The heavily moistening, Yin-nourishing nature of this formula (especially the large dose of Mai Men Dong) can trap existing Dampness and worsen phlegm accumulation in patients with a greasy tongue coating, heavy limbs, or copious watery sputum.

Caution

Cough or wheezing caused by external Wind-Cold invasion. When a pathogen is still lodged at the Exterior level, Yin-nourishing formulas can retain the pathogen inward rather than expelling it. The exterior condition should be resolved first before using this formula.

Caution

High fever with irritability from Excess Heat. This formula addresses deficiency Heat arising from depleted Yin, not robust Excess Heat patterns. Using it in cases of high fever with strong, forceful pulse and thick yellow tongue coating would be insufficient and could delay appropriate treatment.

Caution

Active Stomach bleeding or peptic ulcer with hemorrhage. Although the formula treats Stomach Yin deficiency, the Ren Shen (Ginseng) in the formula can potentially affect clotting dynamics. In acute hemorrhagic conditions, the underlying bleeding must be addressed first.

Cautions & Warnings

Although this formula is typically safe for most individuals, it may cause side effects in some people. Pregnant women, nursing mothers, postpartum women, and those with liver disease should use the formula with caution.

As with any Chinese herbal remedy, it is advisable to seek guidance from a qualified TCM practitioner before beginning treatment.

Product Details

Manufacturing, supplier, and product specifications

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Granules

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Treasure of the East

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