Formula

Li Dan Tang

Benefit the Gall Bladder | 利胆汤

Properties

Heat-clearing formulas · Cold

Key Ingredients

Jin Qian Cao

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

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About This Formula

Traditional Chinese Medicine background and properties

Formula Description

A modern clinical formula used to support gallbladder health by clearing heat and dampness from the liver and gallbladder system. It is commonly used for gallbladder inflammation, gallstones, and related digestive discomfort such as pain under the right ribs, nausea, bitter taste in the mouth, and yellowish skin or eyes.

Formula Category

Main Actions

  • Clears Damp-Heat from the Liver and Gallbladder
  • Benefits the Gallbladder
  • Clears Heat and Resolves Toxicity
  • Moves Qi and Alleviates Pain
  • Disperses stagnation in the Gallbladder

TCM Patterns

In TCM, symptoms don't appear randomly — they cluster into recognizable patterns of disharmony that reveal what's out of balance in the body. Li Dan Tang is traditionally associated with these specific patterns.

The following describes this formula's classification within Traditional Chinese Medicine theory and is provided for educational purposes only.

Why Li Dan Tang addresses this pattern

This is the primary pattern addressed by Li Dan Tang. When damp-heat lodges in the Liver and Gallbladder, it obstructs the smooth flow of bile, causing it to stagnate and concentrate. Over time, this stagnation can lead to gallstone formation and gallbladder inflammation. The formula targets this pattern from multiple directions: Jin Qian Cao and Yin Chen Hao directly clear damp-heat and promote bile drainage; Huang Qin dries dampness and clears Gallbladder fire; Da Huang purges the accumulated heat downward; and the Qi-moving herbs (Chai Hu, Yu Jin, Mu Xiang, Zhi Shi) restore the free flow of Liver and Gallbladder Qi that damp-heat has obstructed. The toxin-clearing herbs (Jin Yin Hua, Da Qing Ye) address the toxic heat that manifests when the damp-heat becomes severe enough to cause infection and high fever.

A practitioner would look for one or more of these signs

Pain In The Right Hypochondrium

Distending or sharp pain under the right ribs, often radiating to the right shoulder or back

Bitter Taste In The Mouth

Persistent bitter taste in the mouth, especially in the morning

Nausea

Nausea and aversion to greasy or oily foods

Jaundice

Yellowing of skin and eyes when bile obstruction is present

Dark Urine

Dark yellow or tea-colored urine

Fever

Fever with alternating chills in acute episodes

Constipation

Dry stools or constipation from heat drying the intestinal fluids

How It Addresses the Root Cause

Li Dan Tang addresses a pattern where Dampness and Heat accumulate in the Liver and Gallbladder system, disrupting normal bile flow and causing inflammation and pain. In TCM understanding, the Gallbladder is responsible for storing and excreting bile (a "clear fluid"), and it functions properly only when Liver Qi moves smoothly and the Gallbladder channel is free of obstruction.

When a person eats excessive greasy or rich food, experiences prolonged emotional frustration (which stagnates Liver Qi), or is invaded by external Dampness-Heat, these pathogenic factors can brew in the Liver and Gallbladder. Dampness is heavy and sticky, while Heat is inflammatory and agitating. Together they create a turbid, congested environment where bile thickens, stagnates, and may eventually form stones or trigger infection. This manifests as pain and distension in the right upper abdomen and ribcage area, bitter taste in the mouth, nausea (especially after fatty meals), yellow greasy tongue coating, and in more severe cases, jaundice (yellowing of the skin and eyes).

The formula works by clearing this Dampness-Heat through two main routes: promoting bile secretion and flow ("benefiting the Gallbladder"), and draining the turbid Dampness-Heat downward through the intestines and urine. Simultaneously, it addresses the Qi stagnation that always accompanies Gallbladder disorders by moving Liver Qi and relieving pain. By resolving the root cause (Dampness-Heat accumulation) while also addressing the branch symptoms (pain, nausea, jaundice), the formula restores normal Gallbladder function.

Formula Properties

Temperature

Cold

Taste Profile

Predominantly bitter and cool, with some pungent elements. The bitter taste drains Dampness-Heat and promotes downward movement, while pungent herbs move stagnant Qi in the Liver and Gallbladder.

Target Organs
Liver Gallbladder Stomach Large Intestine
Channels Entered
Liver Gallbladder Stomach Large Intestine

Formula Origin

Modern clinical experience formula (经验方), widely used in contemporary TCM clinical practice for hepatobiliary disorders

This is just partial information on the formula's TCM properties. More detailed information is available on the formula's dedicated page

Ingredients in Li Dan Tang

Detailed information about each herb in Li Dan Tang and their roles

Jin Qian Cao
Jin Qian Cao

Gold Coin Grass

Dosage: 30 - 60g

Temperature Cool
Taste Sweet (甘 gān), Salty (咸 xián), Bland (淡 dàn)
Organ Affinity Liver, Gallbladder, Kidneys, Urinary Bladder
Parts Used Whole plant / Aerial parts (全草 quán cǎo)
Role in Li Dan Tang

The chief herb for clearing damp-heat from the liver and gallbladder, promoting bile flow, and dissolving or expelling gallstones. Its strong stone-dissolving and dampness-clearing properties make it the primary therapeutic agent in this formula.

Yin Chen
Yin Chen

Virgate Wormwood Herb

Dosage: 15 - 30g

Temperature Slightly Cool
Taste Bitter (苦 kǔ), Acrid / Pungent (辛 xīn)
Organ Affinity Spleen, Stomach, Liver, Gallbladder
Parts Used Whole plant / Aerial parts (全草 quán cǎo)
Role in Li Dan Tang

Strongly clears damp-heat from the liver and gallbladder and promotes bile secretion. Works in concert with Jin Qian Cao to resolve jaundice and facilitate the drainage of pathological dampness and heat from the hepatobiliary system.

Huang Qin
Huang Qin

Baical skullcap root

Dosage: 9 - 15g

Temperature Cold
Taste Bitter (苦 kǔ)
Organ Affinity Lungs, Gallbladder, Spleen, Large Intestine, Small Intestine, Heart, Stomach
Parts Used Root (根 gēn)
Role in Li Dan Tang

Clears heat and dries dampness, especially in the upper and middle burners. Targets gallbladder fire and reduces inflammation in the biliary system, reinforcing the heat-clearing action of the King herb.

Chai Hu
Chai Hu

Bupleurum root

Dosage: 9 - 12g

Temperature Slightly Cool
Taste Acrid / Pungent (辛 xīn), Bitter (苦 kǔ)
Organ Affinity Liver, Gallbladder, Lungs
Parts Used Root (根 gēn)
Role in Li Dan Tang

Courses the Liver Qi and resolves Shaoyang-level disorders. Relieves the constraint and stagnation of Liver and Gallbladder Qi that underlies the pain pattern, and guides the formula's actions to the Liver-Gallbladder organ system.

Yu Jin
Yu Jin

Turmeric tuber

Dosage: 9 - 12g

Temperature Cold
Taste Acrid / Pungent (辛 xīn), Bitter (苦 kǔ)
Organ Affinity Heart, Liver, Lungs
Parts Used Tuber (块茎 kuài jīng / 块根 kuài gēn)
Role in Li Dan Tang

Moves Blood and Qi, resolves stasis, and benefits the gallbladder. Addresses the pain associated with Qi stagnation and Blood stasis in the flanks while also promoting bile flow.

Mu Xiang
Mu Xiang

Costus root

Dosage: 6 - 9g

Temperature Warm
Taste Acrid / Pungent (辛 xīn), Bitter (苦 kǔ)
Organ Affinity Spleen, Stomach, Large Intestine, San Jiao (Triple Burner), Gallbladder
Parts Used Root (根 gēn)
Role in Li Dan Tang

Promotes the movement of Qi, alleviates pain, and regulates the digestive system. Addresses the abdominal distention, bloating, and pain that accompany biliary disorders by restoring smooth Qi circulation in the middle burner.

Zhi Shi
Zhi Shi

Immature Bitter Orange Fruit

Dosage: 9 - 12g

Temperature Slightly Cool
Taste Bitter (苦 kǔ), Acrid / Pungent (辛 xīn), Sour (酸 suān)
Organ Affinity Spleen, Stomach, Large Intestine
Parts Used Fruit (果 guǒ / 果实 guǒ shí)
Role in Li Dan Tang

Breaks up Qi stagnation and reduces focal distention. Works with Mu Xiang to relieve the fullness and distention in the epigastric and hypochondriac regions, helping to restore normal downward movement of Qi.

Da Huang
Da Huang

Rhubarb root and rhizome

Dosage: 6 - 9g

Temperature Cold
Taste Bitter (苦 kǔ)
Organ Affinity Spleen, Stomach, Large Intestine, Liver, Pericardium
Parts Used Root (根 gēn)
Role in Li Dan Tang

Purges heat through the bowels, clears accumulated toxins, and promotes the downward expulsion of gallstones. By opening the bowels, it provides an exit route for damp-heat and helps to physically flush small stones through the biliary and intestinal tract.

Jin Yin Hua
Jin Yin Hua

Honeysuckle flower

Dosage: 15 - 20g

Temperature Cold
Taste Sweet (甘 gān)
Organ Affinity Lungs, Heart, Stomach, Large Intestine
Parts Used Flower bud (花蕾 huā lěi)
Role in Li Dan Tang

Clears heat and resolves toxicity. Addresses the infectious and inflammatory component of gallbladder disease, helping to reduce swelling and fight bacterial infection in the biliary system.

Da Qing Ye
Da Qing Ye

Isatis leaf

Dosage: 9 - 15g

Temperature Cold
Taste Bitter (苦 kǔ), Salty (咸 xián)
Organ Affinity Heart, Stomach, Liver
Parts Used Leaf (叶 yè)
Role in Li Dan Tang

Clears heat and cools the Blood, resolves toxicity. Reinforces the anti-inflammatory and anti-infective actions of the formula, particularly useful when there is fever or signs of systemic toxicity accompanying the gallbladder condition.

Gan Cao
Gan Cao

Licorice root

Dosage: 3 - 6g

Temperature Neutral
Taste Sweet (甘 gān)
Organ Affinity Heart, Lungs, Spleen, Stomach
Parts Used Root (根 gēn)
Role in Li Dan Tang

Harmonizes all the herbs in the formula, moderates the harsh properties of the bitter cold and purgative ingredients, and protects the Stomach from damage by the strongly draining herbs.

Usage & Safety

How to use this formula and important safety information

Important Medical Disclaimer

The information provided here is for educational purposes only and is not intended as medical advice or to replace consultation with a qualified healthcare professional. This formula is a dietary supplement and has not been evaluated by the FDA. It is not intended to diagnose, treat, cure, or prevent any disease.

Always consult with a qualified healthcare provider, particularly if you are pregnant, nursing, have a medical condition, or are taking other medications. Discontinue use and consult your healthcare provider if you experience any adverse reactions.

Recommended Dosage

Instructions for safe storage and consumption

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Best Time to Take

30 minutes after meals, twice daily (morning and evening). Taking after meals helps coordinate with natural bile secretion that occurs during digestion.

Typical Duration

Acute cholecystitis flares: 7-14 days. Chronic gallbladder conditions or gallstone management: 4-8 weeks, reassessed by practitioner with imaging if appropriate.

Dietary Advice

Avoid greasy, fatty, and fried foods, which directly burden the Gallbladder and worsen Dampness-Heat. Reduce alcohol intake, as alcohol generates Dampness and Heat in the Liver and Gallbladder. Avoid spicy, heavily seasoned foods that may aggravate Heat. Eat light, easily digestible meals with plenty of vegetables, especially bitter greens (which support Liver-Gallbladder clearing). Favor foods that gently drain Dampness such as barley (Yi Yi Ren), mung beans, winter melon, and lotus seed. Small, frequent meals are preferable to large heavy ones, as they reduce the burden on the Gallbladder.

Special Populations

Pregnancy

Contraindicated during pregnancy. Da Huang (Rhubarb) is a well-known pregnancy-restricted herb that promotes intestinal peristalsis and may stimulate uterine contractions. The formula's overall strongly bitter-cold nature may also compromise fetal development. Pregnant women with gallbladder complaints should consult their healthcare provider for safer alternatives.

Breastfeeding

Use with caution during breastfeeding. Da Huang (Rhubarb) contains anthraquinone compounds that can pass into breast milk and may cause loose stools or diarrhea in the nursing infant. The bitter-cold nature of multiple herbs (Huang Qin, Da Qing Ye) could theoretically affect the quality or quantity of breast milk by injuring Spleen Qi. If this formula is clinically necessary for a breastfeeding mother, consider reducing Da Huang dosage and monitoring the infant for digestive changes. Consult a qualified practitioner.

Pediatric Use

Li Dan Tang is not commonly used in pediatric practice, as cholecystitis and gallstones are rare in children. If needed for adolescents, dosage should be reduced to approximately one-third to one-half of the adult dose depending on body weight and age. Da Huang (Rhubarb) dosage should be particularly conservative in children, as their digestive systems are more sensitive to its purgative effects. This formula should only be used in children under close supervision by a qualified practitioner, and the cold nature of the formula must be balanced against the tendency of children's Spleen Qi to be relatively immature.

Drug Interactions

Anticoagulants and antiplatelet drugs (e.g. warfarin, heparin, aspirin, clopidogrel): Da Huang (Rhubarb) has demonstrated blood-moving and mild anticoagulant properties. Concurrent use may increase bleeding risk.

Cardiac glycosides (e.g. digoxin): Da Huang's purgative effect can cause potassium loss through diarrhea, potentially increasing sensitivity to digoxin toxicity.

Antihypertensive medications: Huang Qin (Scutellaria) has mild hypotensive effects. Combined use may potentiate blood pressure lowering.

Antibiotics and anti-infective agents: Huang Qin and Jin Yin Hua have antibacterial properties. While this may be complementary, practitioners should be aware of possible additive effects if the patient is already on antibiotics for cholecystitis.

Iron supplements and mineral medications: The tannins in Da Huang can bind iron and other minerals, reducing their absorption. Separate administration by at least 2 hours.

Ursodeoxycholic acid (UDCA) and other cholagogues: This formula has strong cholagogue (bile-promoting) action. Combined use with pharmaceutical cholagogues may produce excessive bile stimulation. Coordinate timing and dosing with the prescribing physician.

Contraindications

Avoid

Pregnancy. The formula contains Da Huang (Rhubarb), which stimulates intestinal peristalsis and may promote uterine contractions, and several strongly bitter-cold herbs that could potentially harm the fetus.

Caution

Patients with Spleen and Stomach deficiency Cold (weak digestion with cold signs). The formula is predominantly cold in nature and may further injure the Spleen Yang, worsening loose stools, poor appetite, and abdominal cold pain.

Caution

Yin deficiency with no Dampness-Heat signs. The bitter-cold, drying herbs in this formula can further damage Yin fluids in patients who have dry mouth, dry stools, thin red tongue with little coating, and no greasy tongue coating.

Avoid

Gallbladder duct obstruction by large stones (greater than 10mm) or acute biliary obstruction with signs of sepsis. This is a surgical emergency requiring immediate medical intervention; herbal therapy alone is insufficient.

Caution

Active hemorrhage or patients on anticoagulant therapy. Da Huang (Rhubarb) has blood-moving properties that may worsen bleeding.

Cautions & Warnings

Li Dan Tang is typically safe for most individuals, but it can lead to side effects in some cases. Pregnant, nursing, or postpartum women, as well as those with liver conditions, should use this formula cautiously and preferably under professional supervision.

As with any Chinese herbal remedy, it is advisable to seek guidance from a qualified Traditional Chinese Medicine (TCM) practitioner before beginning treatment with Liu Wei Di Huang Wan.

Product Details

Manufacturing, supplier, and product specifications

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Granules

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