Formula

Ku Shen Tang

苦參湯

Also known as:

Kushen Tang , Sophora Wash , Sophora Flavescens Decoction

Properties

External-use formulas · Cold

Key Ingredients

Ku Shen, Ju Hua

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Select Product Type

Select Supplier

Select Size

Quantity

$69.00 ($0.69/g)
Made to order · Non-cancellable once ordered · Policy
For shipments to: United States Change
Standard Shipping (3-5 business days): $4.99
Express Shipping (1-2 business days): $9.99
Free shipping on orders over $75

About This Formula

Traditional Chinese Medicine background and properties

Formula Description

A classical external wash formula used to relieve itchy, inflamed skin conditions caused by Dampness and Heat. It combines herbs that clear Heat, dry Dampness, dispel Wind, and stop itching, and is applied by fumigating and washing the affected area. Commonly used for eczema, dermatitis, scabies, fungal infections, and vaginal itching.

Formula Category

Main Actions

  • Clears Heat and dries Dampness
  • Kills Parasites and Stops Itching
  • Resolves Toxicity

TCM Patterns

In TCM, symptoms don't appear randomly — they cluster into recognizable patterns of disharmony that reveal what's out of balance in the body. Ku Shen Tang is traditionally associated with these specific patterns.

The following describes this formula's classification within Traditional Chinese Medicine theory and is provided for educational purposes only.

Why Ku Shen Tang addresses this pattern

When Damp-Heat accumulates in the skin and flesh, it produces red, inflamed, weeping, or crusted skin lesions with intense itching. The Dampness causes oozing and heaviness while the Heat produces redness and burning. Ku Shen Tang directly targets this pathomechanism through its combination of powerfully Dampness-drying herbs (Ku Shen, She Chuang Zi, Huang Bo, Di Fu Zi) and Heat-clearing, toxin-resolving herbs (Jin Yin Hua, Ju Hua). By applying the formula externally as a wash, the medicinal properties reach the affected skin directly, clearing the local Damp-Heat accumulation and relieving the itching.

A practitioner would look for one or more of these signs

Skin Itching

Intense itching that worsens with heat and moisture

Skin Rashes

Red, inflamed skin lesions with possible weeping or crusting

Eczema

Recurrent eczema with oozing and itching

Sore

Sores or ulcerations on the skin with discharge

Vaginal Itching

Itching of the genital or perianal area

How It Addresses the Root Cause

Ku Shen Tang addresses a pattern in which Damp-Heat and toxic pathogens accumulate in the Lower Burner, particularly affecting the genital region. In Zhang Zhongjing's original context, it was prescribed specifically for the "lower erosion" stage of Fox-Creeper disease (狐惑病, a condition now often compared to Behçet's disease), where ulcerative lesions develop on the genitals.

The underlying disease logic works as follows: when Dampness brews internally and transforms into Heat, this Damp-Heat settles downward due to its heavy, turbid nature. When it concentrates in the Lower Burner, it can corrode the mucous membranes and skin of the genital and perianal areas, causing sores, itching, discharge, and erosion. Classical commentators explain that this Damp-Heat also produces an upward reflection: because the lower orifices and the throat are connected through the body's internal channel network, lower Damp-Heat toxicity paradoxically causes throat dryness above. The key insight is that treating the root problem below (the Damp-Heat erosion) resolves the seemingly unrelated symptom above (the dry throat).

In broader modern clinical use, the same mechanism applies to any condition where Damp-Heat lodges in the skin or mucous membranes, generating itching, redness, swelling, and sores. Whether the issue is eczema, dermatitis, fungal infections, or vaginal itching, the fundamental pathological process is the same: Dampness and Heat intertwine, breed toxicity, and irritate the tissues.

Formula Properties

Temperature

Cold

Taste Profile

Intensely bitter, with a cold and somewhat acrid quality. The bitter taste drives the formula's core actions: drying Dampness, clearing Heat, and directing the action downward to the Lower Burner.

Target Organs
Heart Liver Large Intestine Urinary Bladder Stomach
Channels Entered
Heart Liver Stomach Large Intestine Bladder

Formula Origin

疡科心得集 (Yáng Kē Xīn Dé Jí) by Gāo Bǐngjūn (高秉钧)

This is just partial information on the formula's TCM properties. More detailed information is available on the formula's dedicated page

Ingredients in Ku Shen Tang

Detailed information about each herb in Ku Shen Tang and their roles

Kings
Deputies
Assistants
Envoys
Ku Shen
Ku Shen

Sophora root

Dosage: 60g

Temperature Cold
Taste Bitter (苦 kǔ)
Organ Affinity Heart, Liver, Stomach, Large Intestine, Urinary Bladder
Parts Used Root (根 gēn)
Role in Ku Shen Tang

The chief herb and namesake of the formula. Ku Shen powerfully clears Heat, dries Dampness, dispels Wind, kills parasites, and stops itching. Its bitter and cold nature directly targets the Damp-Heat and toxic pathogens that cause skin inflammation and itching.

Ju Hua
Ju Hua

Chrysanthemum flower

Dosage: 60g

Temperature Slightly Cool
Taste Sweet (甘 gān), Bitter (苦 kǔ)
Organ Affinity Lungs, Liver
Parts Used Flower (花 huā)
Role in Ku Shen Tang

Used in large dose equal to Ku Shen, chrysanthemum disperses Wind-Heat from the skin surface and clears toxic Heat. Together with Ku Shen it addresses both the superficial Wind and the deeper Damp-Heat components of skin disease.

Jin Yin Hua
Jin Yin Hua

Honeysuckle flower

Dosage: 30g

Temperature Cold
Taste Sweet (甘 gān)
Organ Affinity Lungs, Heart, Stomach, Large Intestine
Parts Used Flower bud (花蕾 huā lěi)
Role in Ku Shen Tang

Clears Heat and resolves toxicity. Supports the King herbs by addressing the toxic-Heat component of skin lesions, particularly where there is redness, swelling, or secondary infection.

She Chuang Zi
She Chuang Zi

Cnidium seed

Dosage: 30g

Temperature Warm
Taste Acrid / Pungent (辛 xīn), Bitter (苦 kǔ)
Organ Affinity Kidneys, Spleen
Parts Used Fruit (果 guǒ / 果实 guǒ shí)
Role in Ku Shen Tang

Dries Dampness, kills parasites, and stops itching when applied topically. Particularly effective for Damp-type skin lesions with weeping, and for genital itching from parasitic or fungal causes.

Huang Bo
Huang Bo

Phellodendron bark

Dosage: 15g

Temperature Cold
Taste Bitter (苦 kǔ)
Organ Affinity Kidneys, Urinary Bladder
Parts Used Bark (皮 pí / 树皮 shù pí)
Role in Ku Shen Tang

Clears Heat and dries Dampness, especially in the Lower Burner. Reinforces the Heat-clearing and Dampness-drying actions of the King herbs and has strong antimicrobial properties when used topically.

Di Fu Zi
Di Fu Zi

Kochia fruit

Dosage: 15g

Temperature Cold
Taste Bitter (苦 kǔ), Acrid / Pungent (辛 xīn)
Organ Affinity Kidneys, Urinary Bladder
Parts Used Fruit (果 guǒ / 果实 guǒ shí)
Role in Ku Shen Tang

Clears Damp-Heat and stops itching. Particularly useful for widespread skin itching and urticaria-type conditions, reinforcing the anti-itch action of the formula.

Bai Zhi
Bai Zhi

Dahurian angelica root

Dosage: 15g

Temperature Warm
Taste Acrid / Pungent (辛 xīn)
Organ Affinity Lungs, Stomach, Large Intestine
Parts Used Root (根 gēn)
Role in Ku Shen Tang

Dispels Wind-Dampness, reduces swelling, and helps draw out toxins and discharge pus from skin lesions. Its aromatic quality helps the formula penetrate the skin surface.

Shi Chang Pu
Shi Chang Pu

Acorus rhizome

Dosage: 15g

Temperature Warm
Taste Acrid / Pungent (辛 xīn), Bitter (苦 kǔ), Aromatic (芳香 fāng xiāng)
Organ Affinity Heart, Stomach
Parts Used Rhizome (根茎 gēn jīng)
Role in Ku Shen Tang

Aromatically opens the orifices and promotes the penetration of the other herbs into the skin. Also kills parasites and treats sores and scabies. Its aromatic nature helps harmonize the formula and direct its action to the skin surface.

Usage & Safety

How to use this formula and important safety information

Important Medical Disclaimer

The information provided here is for educational purposes only and is not intended as medical advice or to replace consultation with a qualified healthcare professional. This formula is a dietary supplement and has not been evaluated by the FDA. It is not intended to diagnose, treat, cure, or prevent any disease.

Always consult with a qualified healthcare provider, particularly if you are pregnant, nursing, have a medical condition, or are taking other medications. Discontinue use and consult your healthcare provider if you experience any adverse reactions.

Recommended Dosage

Instructions for safe storage and consumption

Loading storage and consumption information...

Best Time to Take

As an external wash, apply after gentle cleansing of the affected area. Best used in the evening before bed to allow overnight benefit, or morning and evening for twice-daily application. The wash solution should be warm (not hot) when applied.

Typical Duration

External wash: 7-14 days per course, applied 1-3 times daily, with reassessment if symptoms persist beyond two weeks.

Dietary Advice

While taking or using Ku Shen Tang (especially if any internal formulations containing Ku Shen are involved), avoid foods that generate Dampness and Heat: greasy, fried, and rich foods; excessive sugar and sweets; alcohol; spicy and pungent foods such as chili, garlic, and raw onions; shellfish and other strongly flavored seafood. Also avoid cold, raw foods that could further impair Spleen function, since the formula's bitter-cold nature already taxes digestive Qi. Favour light, easily digestible foods: plain rice congee, mung beans (which also clear Heat), winter melon, barley (Yi Yi Ren), lotus seed, cucumber, and leafy greens. Adequate hydration with warm water or mild chrysanthemum tea supports the Dampness-clearing process.

Special Populations

Pregnancy

Caution is advised during pregnancy. Ku Shen (Sophora flavescens root) is intensely bitter and cold, and contains matrine alkaloids. While the classical formula is used as an external wash rather than taken internally, absorption through mucous membranes (particularly vaginal application) is possible. Internal use of Ku Shen during pregnancy is generally contraindicated due to its cold, descending nature and alkaloid content, which could potentially affect the fetus. If external use is deemed necessary, it should only be applied to intact skin under direct supervision of a qualified practitioner, and vaginal fumigation/washing should be avoided during pregnancy.

Breastfeeding

As an external wash formula, systemic absorption is limited, and Ku Shen Tang is generally considered compatible with breastfeeding when used topically on intact skin away from the breast area. However, caution is warranted: Ku Shen contains matrine and oxymatrine alkaloids, and if any amount is absorbed systemically (especially through mucous membrane application), transfer into breast milk is theoretically possible. The formula should not be applied to the breast or nipple area, as the infant could directly ingest the bitter, cold herbal residue. If internal use of a Ku Shen-containing formula is being considered during breastfeeding, it should be avoided or used only under close practitioner supervision, as the extremely cold and bitter nature may reduce milk production by damaging Spleen Qi.

Pediatric Use

Ku Shen Tang can be used as an external wash in children for appropriate Damp-Heat skin conditions, but requires significant modification. The wash solution should be diluted 2-3 times with water for infants and young children, as their skin is thinner and more sensitive to the formula's irritating properties. A small patch test on a limited area of skin should be performed first. Treatment sessions should be shorter (5-10 minutes rather than the standard 20-30 minutes for adults). Internal use of Ku Shen in children is generally not recommended due to its extremely bitter, cold nature, which can easily damage the delicate Spleen and Stomach of young children. If internal use is ever considered, dosage should be reduced to one-quarter to one-third of the adult dose and limited to short courses under practitioner supervision.

Drug Interactions

Ku Shen Tang is primarily an external wash formula, which limits systemic drug interactions. However, if the wash is applied to large areas of broken skin or mucous membranes, absorption of matrine alkaloids may occur. The following interactions should be considered:

  • Cytochrome P450 substrates: Matrine and oxymatrine (the primary alkaloids in Ku Shen) have been shown in animal studies to significantly induce CYP2B enzymes and mildly inhibit CYP3A. Drugs metabolized by these pathways (such as certain immunosuppressants, antiretrovirals, and hormonal medications) could theoretically have altered blood levels if significant systemic absorption occurs.
  • Organic cation transporter (OCT) substrates: Oxymatrine has been shown to inhibit human OCT1 transporters. Drugs transported by OCTs (including metformin, certain antivirals, and some cardiovascular drugs) could potentially be affected.
  • Hepatotoxic medications: High doses of matrine/oxymatrine have demonstrated hepatotoxic potential in animal studies. Concurrent use with other hepatotoxic drugs (acetaminophen in high doses, certain statins, or antifungals) warrants caution if significant absorption is possible.
  • Lamivudine and other nucleoside analogs: In vitro studies suggest synergistic antiviral effects between oxymatrine/matrine and lamivudine against hepatitis B, which could be clinically relevant if both are used simultaneously.

These interactions are primarily relevant for internal use or extensive mucosal application. Standard topical use on intact skin carries minimal interaction risk.

Contraindications

Avoid

Cold-type or Yang-deficient skin conditions: Ku Shen is extremely bitter and cold. It should not be used where the skin lesions are caused by internal Cold or Yang deficiency, as its cold nature will worsen the condition.

Avoid

Spleen and Stomach deficiency with Cold: The intensely bitter and cold nature of Ku Shen can severely damage digestive function. If used internally (as in some later adaptations), it is contraindicated for those with weak digestion, poor appetite, or loose stools from Spleen-Stomach Cold.

Caution

Broken skin with active weeping or heavy exudation: when the affected area is actively oozing fluid, the topical wash can be too irritating and may impede healing. The exudation should first be controlled before applying the wash.

Caution

Elderly or constitutionally weak individuals with Kidney Yang deficiency: classical sources such as the Ben Cao Gang Mu specifically warn that those with 'fire deficiency and essence coldness' (火衰精冷) or 'true original insufficiency' (真元不足) should not use Ku Shen.

Caution

Very sensitive or delicate skin (including infants): the wash solution should be diluted 2-3 times for individuals with sensitive skin to avoid irritation.

Cautions & Warnings

Ku Shen Tang is typically safe for most individuals, but it can lead to side effects in some cases. Pregnant, nursing, or postpartum women, as well as those with liver conditions, should use this formula cautiously and preferably under professional supervision.

As with any Chinese herbal remedy, it is advisable to seek guidance from a qualified Traditional Chinese Medicine (TCM) practitioner before beginning treatment with Ku Shen Tang.

Product Details

Manufacturing, supplier, and product specifications

Product Type

Granules

Quantity Description

Loading quantity information...

Concentration Ratio

Loading concentration information...

Fabrication Method

Loading fabrication information...

Supplier Certifications

Loading certifications information...

Supplier Information

Treasure of the East

Loading supplier information...

Loading supplier attributes...

Miscellaneous Info

No additional information available