Formula

Ge Gen Tang

葛根湯

Also known as:

Pueraria Decoction , Pueraria Combination , Ge Gen Ma Huang Tang (葛根麻黄汤) , Ma Huang Ge Gen Tang (麻黄葛根汤) , Gan Ge Jie Ji Tang (干葛解肌汤) , Ma Huang Jia Ge Gen Tang (麻黄加葛根汤)

Properties

Exterior-releasing formulas · Warm

Key Ingredients

Ge Gen

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

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About This Formula

Traditional Chinese Medicine background and properties

Formula Description

A classical formula for the early stages of colds and flu with chills, body aches, and stiffness of the neck and upper back. It works by releasing the body surface to expel cold, while generating fluids to relax tense muscles and sinews. Also commonly used for diarrhea that occurs alongside cold symptoms.

Formula Category

Main Actions

  • Releases the Exterior and Disperses Wind-Cold
  • Induces Sweating and Releases the Exterior
  • Softens and Relaxes the Sinews
  • Raises Yang and Stops Diarrhea

TCM Patterns

In TCM, symptoms don't appear randomly — they cluster into recognizable patterns of disharmony that reveal what's out of balance in the body. Ge Gen Tang is traditionally associated with these specific patterns.

The following describes this formula's classification within Traditional Chinese Medicine theory and is provided for educational purposes only.

Why Ge Gen Tang addresses this pattern

This is the primary pattern Ge Gen Tang addresses. Wind-Cold invades the body surface and lodges in the Greater Yang (Tai Yang) channel, which runs along the back of the neck and down the spine. The cold pathogen tightens the pores, preventing sweating and blocking the normal circulation of Defensive Qi along the surface. Because the Tai Yang channel is obstructed, fluids cannot reach the upper back and neck muscles, causing them to stiffen and become painful. Ge Gen, as the King herb, directly releases the muscle layer and generates fluids to relax the sinews, while Ma Huang and Gui Zhi open the pores and disperse the cold. Bai Shao, Da Zao, and Zhi Gan Cao protect body fluids so that sweating does not become excessive.

A practitioner would look for one or more of these signs

Chills

Strong aversion to cold and wind

Absence of Sweating

No sweating despite feeling feverish

Fever

Fever accompanying the chills

Neck Pain

Stiffness and tension in the nape and upper back (项背强几几)

Body Aches

Generalized body pain and soreness

Headaches

Headache from Wind-Cold obstruction

How It Addresses the Root Cause

Ge Gen Tang addresses a condition where external Wind-Cold has invaded and tightly bound the body's surface, blocking the pores so that sweating cannot occur. The body tries to fight off the cold by generating heat, producing fever and strong chills. Because the cold pathogen specifically attacks along the Tai Yang (Greater Yang) channel, which runs from the back of the head down the spine, the muscles and sinews of the neck and upper back become stiff, tense, and painful. The cold constricts the channel, impeding the normal upward flow of nourishing fluids to these tissues, so they become deprived of moisture and lock up further.

In some cases, the exterior cold also affects the Yang Ming (Stomach and Large Intestine) system simultaneously. When the body's defensive Qi is occupied fighting the surface invasion, the Spleen and Stomach's ability to hold and transform fluids is disrupted. Clear Yang that should ascend to nourish the upper body instead sinks downward, leading to watery diarrhea even as the exterior symptoms persist. This is what the Shang Han Lun describes as a "combined disease" of Greater Yang and Yang Brightness.

The core pathological dynamic is cold obstructing the surface and the channels, with fluids failing to reach the muscles and sinews above while potentially leaking downward through the intestines. The formula must therefore open the surface to expel cold, restore the upward movement of fluids and clear Yang, and relax the constricted sinews.

Formula Properties

Temperature

Warm

Taste Profile

Predominantly acrid (pungent) and sweet, with mild bitterness. The acrid herbs open the surface and disperse cold, while the sweet herbs nourish fluids and harmonize the formula.

Target Organs
Lungs Spleen Stomach Large Intestine Urinary Bladder
Channels Entered
Lung Bladder Stomach Spleen

Formula Origin

Shang Han Lun (Discussion of Cold-Induced Disorders) by Zhang Zhongjing

This is just partial information on the formula's TCM properties. More detailed information is available on the formula's dedicated page

Ingredients in Ge Gen Tang

Detailed information about each herb in Ge Gen Tang and their roles

Kings
Deputies
Assistants
Envoys
Ge Gen
Ge Gen

Kudzu root

Dosage: 12 - 24g

Temperature Cool
Taste Sweet (甘 gān), Acrid / Pungent (辛 xīn)
Organ Affinity Spleen, Stomach, Lungs
Parts Used Root (根 gēn)
Role in Ge Gen Tang

The chief herb of the formula, Ge Gen releases the muscle layer (解肌), generates fluids to moisten and relax the sinews and channels of the neck and upper back, and raises clear Yang Qi in the Stomach and Spleen to stop diarrhea. It addresses the core symptoms of stiff neck and back, and fluid depletion in the muscles.

Ma Huang
Ma Huang

Ephedra

Dosage: 6 - 9g

Temperature Warm
Taste Acrid / Pungent (辛 xīn), Bitter (苦 kǔ)
Organ Affinity Lungs, Urinary Bladder
Parts Used Stem (茎 jīng)
Role in Ge Gen Tang

Assists the King herb by promoting sweating and opening the pores to release Wind-Cold from the body surface. Works together with Ge Gen to open the exterior and dispel pathogenic cold that is blocking the Tai Yang channel, treating the absence of sweating and aversion to cold.

Gui Zhi
Gui Zhi

Cinnamon twig

Dosage: 4 - 9g

Temperature Warm
Taste Acrid / Pungent (辛 xīn), Sweet (甘 gān)
Organ Affinity Heart, Lungs, Urinary Bladder
Parts Used Twig (枝 zhī)
Role in Ge Gen Tang

Warms the channels and assists Ma Huang in releasing the exterior through sweating. Also helps harmonize the Nutritive (Ying) and Defensive (Wei) Qi, ensuring the body's protective layer functions properly after the pathogen is expelled.

Bai Shao
Bai Shao

White peony root

Dosage: 6 - 9g

Temperature Slightly Cool
Taste Bitter (苦 kǔ), Sour (酸 suān)
Organ Affinity Liver, Spleen
Parts Used Root (根 gēn)
Role in Ge Gen Tang

Nourishes Yin and Blood to prevent the sweating herbs from overly depleting body fluids. Softens and relaxes the sinews to complement Ge Gen in relieving muscle tension. Pairs with Gui Zhi to harmonize Nutritive and Defensive Qi.

Sheng Jiang
Sheng Jiang

Fresh ginger rhizome

Dosage: 6 - 9g

Temperature Slightly Warm
Taste Acrid / Pungent (辛 xīn)
Organ Affinity Lungs, Spleen, Stomach
Parts Used Rhizome (根茎 gēn jīng)
Role in Ge Gen Tang

Warms the Middle Burner and assists in dispersing surface cold. Aids digestion and protects the Stomach, and pairs with Da Zao to regulate the Spleen and Stomach while harmonizing the formula.

Da Zao
Da Zao

Chinese date (Jujube fruit)

Dosage: 3 - 6 pieces

Temperature Warm
Taste Sweet (甘 gān)
Organ Affinity Spleen, Stomach, Heart
Parts Used Fruit (果 guǒ / 果实 guǒ shí)
Role in Ge Gen Tang

Tonifies the Spleen and Stomach, nourishes Qi and Blood, and helps generate the body fluids needed to support healthy sweating. Works with Sheng Jiang to protect the digestive system and harmonize the actions of all other herbs.

Gan Cao
Gan Cao

Licorice root

Dosage: 3 - 6g

Temperature Neutral
Taste Sweet (甘 gān)
Organ Affinity Heart, Lungs, Spleen, Stomach
Parts Used Root (根 gēn)
Role in Ge Gen Tang

Harmonizes and moderates all the other herbs in the formula. Tonifies the Spleen and Stomach to support fluid production. Pairs with Bai Shao to relax spasms and ease pain in the muscles and sinews.

Modern Research (4 studies)

  • Antiviral activity of Ge-Gen-Tang against human respiratory syncytial virus (In vitro study, 2012)
  • Real-world study on Ge Gen Tang for common cold symptoms (Observational study with NHIRD analysis, 2022)
See all research on the formula page

Usage & Safety

How to use this formula and important safety information

Important Medical Disclaimer

The information provided here is for educational purposes only and is not intended as medical advice or to replace consultation with a qualified healthcare professional. This formula is a dietary supplement and has not been evaluated by the FDA. It is not intended to diagnose, treat, cure, or prevent any disease.

Always consult with a qualified healthcare provider, particularly if you are pregnant, nursing, have a medical condition, or are taking other medications. Discontinue use and consult your healthcare provider if you experience any adverse reactions.

Recommended Dosage

Instructions for safe storage and consumption

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Best Time to Take

Warm, 2-3 times daily between meals. Take while covered with blankets to promote mild sweating. Stop once a light sweat appears.

Typical Duration

Acute use: 1-3 days. The Shang Han Lun advises stopping the formula once a mild sweat is achieved and symptoms resolve. Maximum 3 doses (days) for a single episode.

Dietary Advice

While taking this formula, avoid cold and raw foods, iced drinks, and greasy or heavy meals, as these can impair the Stomach and Spleen's ability to support the body's fight against the exterior pathogen. Light, warm, easily digestible foods such as rice porridge (congee) are ideal. The Shang Han Lun instructs patients to follow the same dietary restrictions as for Gui Zhi Tang, which includes avoiding raw, cold, sticky, glutinous foods, meat, dairy, and alcohol. After taking the decoction, keep warm and rest under covers to encourage a mild sweat. Stop taking the formula once a light sweat has been achieved and symptoms have improved.

Special Populations

Pregnancy

Use with caution during pregnancy. Ma Huang (Ephedra) is a strong diaphoretic with sympathomimetic properties that may stimulate the cardiovascular system and potentially affect uterine blood flow. While short-term use for acute conditions may be acceptable under close practitioner supervision, the strongly dispersing nature of this formula is generally not ideal during pregnancy. Gui Zhi (Cinnamon twig) also promotes circulation and can be warming, which warrants caution. Pregnant women should consult a qualified practitioner before use, and the formula should not be used without clear clinical indication.

Breastfeeding

Use with caution during breastfeeding. Ma Huang (Ephedra) contains ephedrine alkaloids, which are known to be present in breast milk. Ephedrine may cause irritability, poor sleep, or feeding difficulties in nursing infants. Gan Cao (Licorice) at high doses can also affect fluid balance through mineralocorticoid-like effects. If this formula is needed for an acute condition, it should be used at the lowest effective dose for the shortest possible duration. A qualified practitioner should weigh the mother's need against potential infant exposure.

Pediatric Use

Ge Gen Tang can be used in children for acute Wind-Cold conditions with appropriate dose reduction. Classical sources and modern clinical practice suggest using approximately one-third to one-half of the adult dose for children, adjusted by age and body weight. For very young children (under 3 years), extreme caution is warranted due to the presence of Ma Huang (Ephedra), which may cause restlessness, insomnia, or increased heart rate. Granule formulations (widely used in Japan and Taiwan) are often preferred for children due to ease of administration. The formula has been used clinically for pediatric diarrhea with good results. As with adults, it should only be used for true Wind-Cold excess patterns and discontinued once sweating is achieved and symptoms resolve.

Drug Interactions

Ma Huang (Ephedra) is the primary concern for drug interactions in this formula:

  • MAO inhibitors (e.g. phenelzine, tranylcypromine): Concurrent use is strongly contraindicated. MAO inhibitors can dramatically potentiate the pressor effects of ephedrine, potentially causing a hypertensive crisis.
  • Cardiac glycosides (e.g. digoxin): Ephedrine may increase the risk of cardiac arrhythmias when combined with digoxin or other cardiac glycosides.
  • Antihypertensive medications (e.g. beta-blockers, guanethidine): Ephedrine can antagonize the blood-pressure-lowering effects of these drugs, potentially causing rebound hypertension.
  • Theophylline and other xanthine bronchodilators: Combining ephedrine with theophylline may increase the risk of insomnia, nervousness, and gastrointestinal side effects.
  • Sympathomimetic drugs (e.g. pseudoephedrine, phenylephrine): Additive cardiovascular stimulation can occur, increasing risk of tachycardia and hypertension.

Gan Cao (Licorice): Glycyrrhizin in licorice can cause pseudoaldosteronism (potassium loss, sodium retention, edema, hypertension) and may interact with corticosteroids, diuretics, and antihypertensive medications. It may also reduce the effectiveness of potassium-sparing diuretics and enhance potassium loss from loop or thiazide diuretics.

Contraindications

Avoid

Wind-Heat or warm-febrile disease patterns with sore throat, thirst, and red tongue. This formula is warming and diaphoretic, designed only for Wind-Cold conditions.

Avoid

Exterior deficiency with spontaneous sweating (a Gui Zhi Tang pattern). The presence of Ma Huang makes this formula too strongly diaphoretic for patients who are already sweating.

Caution

Hypertension, cardiac arrhythmias, or cardiovascular disease. Ma Huang (Ephedra) contains ephedrine alkaloids that can raise blood pressure and heart rate.

Caution

Hyperthyroidism or anxiety disorders. The sympathomimetic effects of Ma Huang may worsen palpitations, agitation, and insomnia.

Caution

Patients with Yin deficiency or Blood deficiency. The strongly diaphoretic and warm nature of this formula can further damage Yin and fluids.

Caution

Prostatic hypertrophy or difficulty urinating. Ephedrine alkaloids from Ma Huang can constrict the urethral sphincter and worsen urinary retention.

Cautions & Warnings

Ge Gen Tang is typically safe for most individuals, but it can lead to side effects in some cases. Pregnant, nursing, or postpartum women, as well as those with liver conditions, should use this formula cautiously and preferably under professional supervision.

As with any Chinese herbal remedy, it is advisable to seek guidance from a qualified Traditional Chinese Medicine (TCM) practitioner before beginning treatment with Ge Gen Tang.

Product Details

Manufacturing, supplier, and product specifications

Product Type

Granules

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Treasure of the East

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