Formula

Chai Hu Qing Gan Tang

Bupleurum & Rehmannia Formula | 柴胡清肝汤

Also known as:

Bupleurum Decoction to Clear the Liver , Bupleurum Liver Clearing Decoction , Bupleurum and Rehmannia Combination

Properties

Harmonizing formulas · Cool

Key Ingredients

Chai Hu, Shu Di Huang

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Select Product Type

Select Supplier

Select Size

Quantity

$24.00 ($0.42/g)
Made to order · Non-cancellable once ordered · Policy
For shipments to: United States Change
Standard Shipping (3-5 business days): $4.99
Express Shipping (1-2 business days): $9.99
Free shipping on orders over $75

About This Formula*

Traditional Chinese Medicine background and properties

Formula Description*

A classical formula originally designed to treat early-stage boils and abscesses at the temples, now widely used for any condition involving Liver Fire with toxic swellings such as swollen lymph nodes, chronic tonsillitis, inflammatory skin conditions, and breast inflammation. It works by clearing Heat from the Liver, resolving toxicity, nourishing Blood, and dispersing nodules.

Formula Category*

Main Actions*

  • Clears Liver and Gallbladder Heat
  • Disperses Wind-Heat
  • Purges Fire and Resolves Toxicity
  • Nourishes Blood and cools the Blood
  • Soothes the Liver and Regulates Qi
  • Disperses Swelling and Dissipates Nodules

TCM Patterns*

In TCM, symptoms don't appear randomly — they cluster into recognizable patterns of disharmony that reveal what's out of balance in the body. Chai Hu Qing Gan Tang is traditionally associated with these specific patterns.

The following describes this formula's classification within Traditional Chinese Medicine theory and is provided for educational purposes only.

Why Chai Hu Qing Gan Tang addresses this pattern

When the Liver's Qi becomes constrained, often due to emotional stress or frustration, the stagnation can transform into Fire over time. This Liver Fire blazes upward along the Liver and Gallbladder channels, affecting the head, eyes, ears, and temples. In this formula, Chai Hu spreads the constrained Liver Qi while Huang Qin and Shan Zhi Zi directly drain the accumulated Fire. Sheng Di Huang cools the Blood that has been heated, while the Si Wu Tang foundation (Dang Gui, Bai Shao, Chuan Xiong, Sheng Di Huang) nourishes the Blood and Yin that Fire tends to consume. This two-pronged approach of clearing Fire and nourishing Blood makes the formula particularly suited for Liver Fire patterns where the Fire has already begun to damage Yin and Blood.

A practitioner would look for one or more of these signs

Irritability

Restlessness and easy anger from Liver Fire flaring

Headaches

Particularly at the temples along the Gallbladder channel

Red Eyes

Redness and swelling of the eyes from upward-blazing Fire

Bitter Taste In The Mouth

Bitter taste in the mouth, a hallmark of Liver-Gallbladder Heat

Tinnitus

Ringing or pain in the ears from Fire along the Shaoyang channel

Dry Mouth

Dryness from Heat consuming fluids

How It Addresses the Root Cause*

This formula addresses a pattern where Heat accumulates in the Liver, Gallbladder, and San Jiao (Triple Burner) channels. The Liver prefers smooth, unobstructed movement of Qi. When emotional stress, poor diet, or external Wind-Heat pathogens disturb the Liver, Qi stagnation can develop and transform into Heat over time. This Liver-Gallbladder Heat then rises along the channel pathways toward the head, ears, eyes, and throat, producing symptoms such as headache, tinnitus, red painful eyes, sore throat, and chronic tonsillitis. When this Heat becomes more severe, it can condense into 'Fire Toxin,' manifesting as swollen lymph nodes, boils, abscesses (especially around the temples, ears, and neck), and inflamed skin conditions like eczema.

Because the Liver stores Blood, prolonged Heat in the Liver channel also scorches and consumes the Blood, leading to dry, itchy, or darkened skin and a tendency toward irritability and restlessness. In children, this pattern often presents as what was classically called a 'scrofulous constitution' (腺病质): the child tends to be thin, nervous, prone to skin rashes, swollen tonsils, and frequent upper respiratory infections. The tongue is typically red with a yellow coating, and the pulse is wiry (indicating Liver involvement) and rapid (indicating Heat).

The formula works by simultaneously clearing the excess Heat from the Liver and Gallbladder channels, dispersing Wind-Heat from the surface, resolving toxic swelling, and nourishing Blood to prevent further damage from the Heat. By addressing both the root (Liver-channel Heat) and the branches (toxic swelling, Wind-Heat symptoms), it restores balance to the Liver system and calms the inflammatory processes along its pathways.

Formula Properties*

Temperature

Cool

Taste Profile

Predominantly bitter and acrid with a sweet undertone — bitter to clear Heat and drain Fire, acrid to disperse Wind and move stagnation, sweet to nourish Blood and harmonize.

Target Organs
Liver Gallbladder San Jiao (Triple Burner)
Channels Entered
Liver Gallbladder San Jiao

Formula Origin

Wai Ke Zheng Zong (外科正宗, Orthodox Manual of External Medicine) by Chen Shigong (陈实功)

This is just partial information on the formula's TCM properties. More detailed information is available on the formula's dedicated page

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Product Details

Manufacturing, supplier, and product specifications

Product Type

Granules

Quantity Description

Loading quantity information...

Concentration Ratio

Loading concentration information...

Fabrication Method

Loading fabrication information...

Supplier Certifications

Loading certifications information...

Supplier Information

Treasure of the East

Loading supplier information...

Loading supplier attributes...

Miscellaneous Info

No additional information available

Ingredients in Chai Hu Qing Gan Tang

Detailed information about each herb in Chai Hu Qing Gan Tang and their roles

Chai Hu
Chai Hu

Bupleurum root

Dosage: 3 - 6g

Temperature Slightly Cool
Taste Acrid / Pungent (辛 xīn), Bitter (苦 kǔ)
Organ Affinity Liver, Gallbladder, Lungs
Parts Used Root (根 gēn)
Role in Chai Hu Qing Gan Tang

Spreads Liver Qi, clears Heat from the Liver and Gallbladder channels, and vents pathogenic factors outward from the Shaoyang level. As the lead herb, it addresses the root mechanism of Liver Fire and constraint that drives the formation of toxic swellings.

Shu Di Huang
Shu Di Huang

Prepared Rehmannia root

Dosage: 3 - 6g

Temperature Slightly Warm
Taste Sweet (甘 gān)
Organ Affinity Liver, Kidneys
Parts Used Tuber (块茎 kuài jīng / 块根 kuài gēn)
Role in Chai Hu Qing Gan Tang

Cools the Blood and nourishes Yin to counteract the drying effects of Liver Fire. Works alongside Chai Hu to address both the Heat and the underlying Blood deficiency that allows Fire to flare.

Dang Gui
Dang Gui

Chinese Angelica root

Dosage: 3 - 5g

Temperature Warm
Taste Sweet (甘 gān), Acrid / Pungent (辛 xīn)
Organ Affinity Liver, Heart, Spleen
Parts Used Root (根 gēn)
Role in Chai Hu Qing Gan Tang

Nourishes and invigorates the Blood, supporting the Liver's Blood-storing function. Prevents the Heat-clearing herbs from further damaging Yin and Blood, and promotes healing of sores by ensuring adequate Blood circulation.

Bai Shao
Bai Shao

White peony root

Dosage: 3 - 5g

Temperature Slightly Cool
Taste Bitter (苦 kǔ), Sour (酸 suān)
Organ Affinity Liver, Spleen
Parts Used Root (根 gēn)
Role in Chai Hu Qing Gan Tang

Nourishes Liver Blood and restrains Liver Yang, softening the Liver to prevent Fire from flaring further. Pairs with Dang Gui to form the Blood-nourishing foundation of the formula.

Chuan Xiong
Chuan Xiong

Sichuan lovage rhizome

Dosage: 3 - 5g

Temperature Warm
Taste Acrid / Pungent (辛 xīn)
Organ Affinity Liver, Gallbladder, Pericardium
Parts Used Rhizome (根茎 gēn jīng)
Role in Chai Hu Qing Gan Tang

Moves Blood and promotes Qi circulation, preventing Blood stasis that could worsen swelling and nodulation. Directs the Blood-nourishing herbs into active circulation and alleviates pain.

Huang Qin
Huang Qin

Baical skullcap root

Dosage: 3 - 5g

Temperature Cold
Taste Bitter (苦 kǔ)
Organ Affinity Lungs, Gallbladder, Spleen, Large Intestine, Small Intestine, Heart, Stomach
Parts Used Root (根 gēn)
Role in Chai Hu Qing Gan Tang

Clears Heat and drains Fire from the Liver and Gallbladder, reinforcing the Heat-clearing action. Its bitter-cold nature directly purges the accumulated Fire toxin contributing to abscess formation.

Zhi Zi
Zhi Zi

Gardenia fruit

Dosage: 3 - 5g

Temperature Cold
Taste Bitter (苦 kǔ)
Organ Affinity Heart, Lungs, San Jiao (Triple Burner)
Parts Used Fruit (果 guǒ / 果实 guǒ shí)
Role in Chai Hu Qing Gan Tang

Clears Heat from all three Burners and drains Damp-Heat downward through the urine. Particularly effective at clearing Liver Fire and resolving irritability.

Lian Qiao
Lian Qiao

Forsythia fruit

Dosage: 3 - 5g

Temperature Slightly Cool
Taste Bitter (苦 kǔ)
Organ Affinity Lungs, Heart, Small Intestine
Parts Used Fruit (果 guǒ / 果实 guǒ shí)
Role in Chai Hu Qing Gan Tang

Clears Heat, resolves toxicity, and disperses nodules and swellings. Particularly important for the formula's surgical application in treating early-stage boils and abscesses on the temples.

Tian Hua Fen
Tian Hua Fen

Trichosanthes root

Dosage: 3 - 5g

Temperature Cool
Taste Sweet (甘 gān), Bitter (苦 kǔ)
Organ Affinity Lungs, Stomach
Parts Used Root (根 gēn)
Role in Chai Hu Qing Gan Tang

Clears Heat, generates fluids, and reduces swelling. Helps counteract the fluid-damaging effects of Fire and supports the resolution of abscesses by draining pus.

Niu Bang Zi
Niu Bang Zi

Burdock fruit

Dosage: 3 - 5g

Temperature Cold
Taste Acrid / Pungent (辛 xīn), Bitter (苦 kǔ)
Organ Affinity Lungs, Stomach
Parts Used Seed (种子 zhǒng zǐ / 子 zǐ / 仁 rén)
Role in Chai Hu Qing Gan Tang

Disperses Wind-Heat, clears toxicity, benefits the throat, and promotes the eruption of skin rashes. Addresses the exterior Wind-Heat component and helps vent pathogenic Heat outward through the skin.

Fang Feng
Fang Feng

Siler root

Dosage: 3 - 5g

Temperature Slightly Warm
Taste Acrid / Pungent (辛 xīn), Sweet (甘 gān)
Organ Affinity Urinary Bladder, Liver, Spleen
Parts Used Root (根 gēn)
Role in Chai Hu Qing Gan Tang

Expels Wind and releases the exterior, helping vent pathogenic Heat outward. Its gentle dispersing nature complements the interior Heat-clearing herbs by addressing any residual external pathogenic factor.

Gan Cao
Gan Cao

Licorice root

Dosage: 3 - 5g

Temperature Neutral
Taste Sweet (甘 gān)
Organ Affinity Heart, Lungs, Spleen, Stomach
Parts Used Root (根 gēn)
Role in Chai Hu Qing Gan Tang

Harmonizes all the herbs in the formula, clears Heat, and resolves toxicity. The use of Gan Cao Jie (the node section of licorice root) specifically enhances its ability to clear toxins and guide the formula's action toward dispersing nodules.

Modern Research (1 study)

  • Application of Microwave Ablation Combined With Chai Hu Qing Gan Tang in the Treatment of Idiopathic Granulomatous Mastitis (Clinical Study, 2025)
See all research on the formula page

Usage & Safety

How to use this formula and important safety information

Important Medical Disclaimer

The information provided here is for educational purposes only and is not intended as medical advice or to replace consultation with a qualified healthcare professional. This formula is a dietary supplement and has not been evaluated by the FDA. It is not intended to diagnose, treat, cure, or prevent any disease.

Always consult with a qualified healthcare provider, particularly if you are pregnant, nursing, have a medical condition, or are taking other medications. Discontinue use and consult your healthcare provider if you experience any adverse reactions.

Recommended Dosage

Instructions for safe storage and consumption

Loading storage and consumption information...

Best Time to Take

30 minutes before meals, or between meals on an empty stomach, twice daily (morning and evening).

Typical Duration

Acute conditions (boils, tonsillitis flare-ups): 5-10 days. Constitutional use in children: 4-8 weeks, then reassessed by practitioner.

Dietary Advice

While taking this formula, avoid foods that generate Heat or aggravate Liver Fire, including alcohol, spicy foods (chili peppers, black pepper, raw garlic, raw ginger), fried and greasy foods, and rich meats such as lamb and venison. Coffee and strong tea should also be limited as they can stir Liver Heat. Foods that gently clear Heat and support the Liver are recommended: leafy greens (especially celery, chrysanthemum greens, and watercress), mung beans, cucumber, pears, watermelon (in moderation), and chrysanthemum tea. Since the formula is cooling, patients with weak digestion should ensure food is warm and easily digestible to avoid further taxing the Spleen and Stomach.

Special Populations

Pregnancy

Use with caution during pregnancy. The formula contains Chuan Xiong (Ligusticum) and Dang Gui (Angelica sinensis), both of which activate Blood circulation and could theoretically stimulate uterine activity. Chi Shao (Red Peony) also moves Blood and cools it. Additionally, Niu Bang Zi (Burdock seed) has a slippery, descending quality. While none of these herbs are classified as strictly prohibited in pregnancy, the overall Blood-moving and strongly cooling character of this formula makes it unsuitable for routine use during pregnancy. If clinically necessary, a qualified practitioner should supervise use, adjust dosages, and monitor carefully.

Breastfeeding

Limited safety data exists for this formula during breastfeeding. The formula contains bitter-cold herbs (Huang Qin, Shan Zhi Zi, Lian Qiao) whose constituents may transfer to breast milk in small amounts and could potentially cause loose stools or decreased appetite in the nursing infant. Sheng Di Huang (raw Rehmannia) is cold in nature and may also affect the infant's digestion indirectly. If a breastfeeding mother requires this formula for an acute Liver-Heat condition, short-term use under practitioner guidance is likely acceptable, but the infant should be monitored for digestive changes. Prolonged use is not recommended without professional supervision.

Pediatric Use

Chai Hu Qing Gan Tang is historically one of the most important pediatric formulas, particularly in the Japanese Kampo tradition where it is a primary prescription for children with a 'scrofulous' or 'detoxification' constitution. It is commonly used for children who are nervous, irritable, prone to swollen tonsils, chronic ear infections, eczema, and skin rashes. Dosage should be adjusted by age and body weight. As a general guideline: infants under 2 years typically receive one-quarter to one-third of the adult dose; children ages 2-6 receive one-third to one-half; children ages 6-12 receive one-half to two-thirds. The Tsumura granule formulation (Japan) provides specific pediatric dosing: typically 2.5g daily for small children, increased toward 5-7.5g daily for older children. Because the formula is bitter-cold in nature, prolonged use may affect appetite or digestion in children with already weak Spleen-Stomach function. If the child develops loose stools or decreased appetite, the dose should be reduced or the formula discontinued. Practitioners often combine it with mild digestive support if used over several weeks.

Cautions & Warnings

Chai Hu Qing Tan Tang is typically safe for most individuals, but it can lead to side effects in some cases. Pregnant, nursing, or postpartum women, as well as those with liver conditions, should use this formula cautiously and preferably under professional supervision.

As with any Chinese herbal remedy, it is advisable to seek guidance from a qualified Traditional Chinese Medicine (TCM) practitioner before beginning treatment with Liu Wei Di Huang Wan.