Dang Gui Gao

Angelica Paste · 當歸膏

Also known as: Shen Xiao Dang Gui Gao (神效当归膏), Shen Xiao Bai Gao (神效白膏)

A traditional external paste made from Angelica root (Dang Gui), sesame oil, and beeswax, used to promote wound healing, relieve pain, and regenerate tissue. It is applied topically for burns, scalds, chronic non-healing sores, and skin ulcers.

Origin Tai Ping Hui Min He Ji Ju Fang (太平惠民和剂局方) — Sòng dynasty, 1078–1110 CE
Composition 3 herbs
Dang Gui
King
Dang Gui
Ma You
Deputy
Ma You
Feng La
Assistant
Feng La
Explore composition

Educational content Consult qualified TCM practitioners for diagnosis and treatment

Patterns Addressed

In TCM, symptoms don't appear randomly — they cluster into recognizable patterns of disharmony that reveal what's out of balance in the body. Dang Gui Gao is designed to correct these specific patterns.

Why Dang Gui Gao addresses this pattern

In TCM external medicine, damaged tissue from burns, trauma, or chronic ulceration leads to local Blood Stagnation. When Blood cannot flow freely through the injured area, pain intensifies, healing stalls, and tissue may become necrotic. Dang Gui Gao addresses this directly: the warm, Blood-invigorating action of Dang Gui penetrates the local tissue via the sesame oil base, moving stagnant Blood, relieving pain, and encouraging fresh Blood to nourish the wound. The sesame oil further moistens the damaged area, while beeswax provides a protective layer that allows healing to proceed undisturbed.

A practitioner would look for one or more of these signs

Non-Healing Wounds

Chronic wounds or ulcers that fail to close

Skin Burns

Burns and scalds with pain and tissue damage

Ulcer

Open sores with poor granulation

Commonly Prescribed For

These conditions can arise from the patterns above. A practitioner would consider Dang Gui Gao when these conditions are specifically caused by those patterns — not for all cases of these conditions.

Arises from: Blood Stagnation

TCM Interpretation

In TCM, burns and scalds are understood as the result of Fire-Heat toxin invading the skin and flesh. The intense heat damages local blood vessels and tissue, causing immediate Blood Stagnation (the body's circulation is disrupted at the burn site). This results in blistering, redness, severe pain, and in serious cases, tissue necrosis. As the burn evolves, the Heat toxin may spread, causing surrounding tissue inflammation. The damaged area requires both the clearing of residual Heat toxin and the promotion of new tissue growth.

Why Dang Gui Gao Helps

Dang Gui Gao works on multiple levels for burn care. Dang Gui's Blood-invigorating action breaks up the local Blood Stagnation caused by thermal injury, while its tissue-regenerating properties (sheng ji) encourage the growth of new flesh. The sesame oil base provides a cool, moistening layer that soothes the burning sensation, prevents the wound from drying out, and helps draw residual heat from the tissue. Beeswax seals and protects the vulnerable burn surface. Together, these ingredients create an environment conducive to healing: moist, protected, with active blood circulation to bring nourishment to the damaged tissue.

Also commonly used for

Carbuncles

Abscesses and carbuncles after drainage

Eczema

Dry, cracked eczema

Psoriasis

Dry, scaly psoriasis lesions (snake-skin pattern)

Trauma

Wounds from cuts, abrasions, and contusions

Sore

Bedsores and pressure ulcers

What This Formula Does

Every TCM formula has a specific set of actions — here's what Dang Gui Gao does in the body, explained in both everyday and TCM terms

Therapeutic focus

In practical terms, Dang Gui Gao is primarily used to support these areas of health:

TCM Actions

In TCM terminology, these are the specific therapeutic actions that Dang Gui Gao performs to restore balance in the body:

How It Addresses the Root Cause

TCM doesn't just suppress symptoms — it aims to resolve the underlying imbalance. Here's how Dang Gui Gao works at the root level.

Dang Gui Gao addresses the local pathology of burns and scalds (汤火伤). When the skin is damaged by hot liquids or fire, the intense external Heat invades the local flesh and tissues. In TCM terms, this external Heat transforms into Heat toxin (热毒) that lodges in the skin and muscles. The toxin congests locally (毒气壅盛), obstructing the normal flow of Qi and Blood in the affected area. This stagnation produces the characteristic signs of redness, swelling, and severe pain.

As the Heat toxin accumulates and festers, it damages the local flesh, causing tissue to break down. Blistering occurs as fluids are forced out by the Heat, and if the toxin is not resolved, the damaged tissue rots and turns into pus (腐化成脓). Meanwhile, the intense Heat consumes local Body Fluids and Blood, leaving the tissue dry and unable to heal. The wound remains open, painful, and vulnerable to further damage.

The formula works by clearing the local Heat toxin from the skin surface while simultaneously nourishing Blood and moistening the damaged tissue. By drawing out toxin and promoting the generation of new flesh, it addresses both the root cause (Heat toxin congestion) and the consequence (tissue damage and failure to heal). The oily, moistening base protects the wound from further exposure and creates a favorable environment for tissue repair.

Formula Properties

Every formula has an inherent temperature, taste, and affinity for specific organs — these properties determine how it interacts with the body

Overall Temperature

Warm

Taste Profile

Predominantly sweet and pungent from Dang Gui, with an oily, rich texture from sesame oil and beeswax. The sweetness nourishes and generates flesh, while the pungency promotes Blood circulation to the wound site.

Target Organs

Channels Entered

Ingredients

3 herbs

The herbs that make up Dang Gui Gao, organized by their role in the prescription

King — Main ingredient driving the formula
Deputy — Assists and enhances the King
Assistant — Supports or moderates other herbs
King — Main ingredient driving the formula
Dang Gui

Dang Gui

Dong quai

Dosage 30g
Temperature Warm
Taste Pungent, Sweet
Organ Affinity Heart, Liver, Spleen
Preparation Sliced raw (生锉). Fried in the sesame oil until charred black, then strained out.

Role in Dang Gui Gao

The principal medicinal herb in this paste. Dang Gui nourishes and invigorates Blood, promotes tissue regeneration, relieves pain, and moistens dryness. Its warm, sweet, and pungent nature helps stimulate local blood circulation to damaged tissue, encouraging the growth of new flesh and the healing of sores and burns.
Deputy — Assists and enhances the King
Ma You

Ma You

Sesame oil

Dosage 120g (4 liang)
Temperature Cool
Taste Sweet
Organ Affinity Large Intestine
Preparation Heated first before adding Dang Gui for extraction.

Role in Dang Gui Gao

Serves as both the extraction medium and a therapeutic agent. Sesame oil moistens and protects damaged skin, resolves mild toxicity, and acts as the base that carries the medicinal properties of Dang Gui to the wound surface. Its lubricating quality prevents the paste from sticking painfully to raw tissue.
Assistant — Supports or moderates other herbs
Feng La

Feng La

Beeswax

Dosage 30g (1 liang)
Temperature Warm
Taste Sweet
Organ Affinity Spleen
Preparation Added to the strained, hot medicated oil and stirred rapidly until fully dissolved and blended.

Role in Dang Gui Gao

Acts as the solidifying agent that gives the paste its semi-solid consistency for topical application. Beeswax also has mild detoxifying, wound-sealing, and pain-relieving properties, and promotes the generation of new tissue. It creates a protective barrier over the wound surface.

Why This Combination Works

How the herbs in Dang Gui Gao complement each other

Overall strategy

This paste is designed for external application to damaged skin and tissue. By extracting the Blood-nourishing and pain-relieving properties of Dang Gui into a protective, moistening oil-and-wax base, the formula creates a healing environment that simultaneously invigorates local blood flow, generates new flesh, relieves pain, and shields the wound from further irritation.

King herbs

Dang Gui is the sole medicinal herb and the heart of this formula. Its warm nature and Blood-invigorating action promote local circulation to the wound site, which is essential for tissue regeneration. Dang Gui is historically prized in external surgery (Wai Ke) for its ability to promote the growth of new flesh (sheng ji) and expel pus, making it ideal for burns, ulcers, and non-healing sores.

Deputy herbs

Sesame oil (Ma You) is more than a passive vehicle. It is sweet, cool, and lubricating, capable of neutralizing mild toxins and moistening damaged tissue. By frying Dang Gui in the oil, the fat-soluble active components are extracted into the base, creating a medicated oil that delivers therapeutic effects directly to the wound.

Assistant herbs

Beeswax (Huang La) is a restraining assistant that solidifies the formula into a spreadable paste and adds its own mild wound-healing properties. It helps seal the wound, reduce discharge, and promote tissue closure. The waxy barrier also protects the healing tissue from environmental contamination.

Notable synergies

The combination of Dang Gui's blood-moving warmth with sesame oil's gentle cooling and moistening creates a balanced topical agent that warms without drying and moistens without creating stagnation. This makes the paste suitable for both fresh burns (where excessive heat needs to be gently drawn out) and chronic non-healing wounds (where stagnant blood circulation needs stimulation).

How to Prepare

Traditional preparation instructions for Dang Gui Gao

Heat the sesame oil (Ma You, 120g) until very hot. Add the sliced raw Dang Gui (30g) and fry over moderate heat until the herb turns charred black. Strain out the residue thoroughly.

Return the medicated oil to the heat and add the beeswax (Huang La, 30g). Stir rapidly and continuously as the wax melts and blends into the oil. Allow the mixture to cool, then store in a clean ceramic or porcelain container with a lid.

To use: spread the paste onto a piece of clean cloth and apply directly to the affected area. Change the dressing as needed.

Common Modifications

How practitioners adapt Dang Gui Gao for specific situations

Added
Shu Di huang

30g, to cool Blood and clear residual Heat from the burn

Zi Cao

15g, to cool Blood, resolve toxicity, and promote tissue regeneration

Adding Sheng Di Huang and Zi Cao strengthens the formula's ability to clear Heat toxin and cool the Blood, which is critical in acute burns where Fire-Heat damage is the primary pathogenic factor.

Educational content — always consult a qualified healthcare provider or TCM practitioner before using any herbal formula.

Contraindications

Situations where Dang Gui Gao should not be used or requires extra caution

Caution

Open, heavily infected wounds with copious pus discharge requiring systemic antibiotic treatment. Topical application alone is insufficient for deep or widespread infections.

Avoid

Known allergy or hypersensitivity to sesame oil (Ma You), beeswax (Huang La), or Dang Gui (Angelica sinensis). Discontinue immediately if redness, swelling, or irritation worsens after application.

Avoid

Severe or deep third-degree burns. These require emergency medical care and cannot be managed with topical herbal ointments alone.

Caution

Yin-deficiency with vigorous Fire patterns where Heat signs are predominantly internal rather than at the skin surface. This ointment addresses local external Heat toxin, not systemic Yin-deficiency Heat.

Special Populations

Important considerations for pregnancy, breastfeeding, and pediatric use

Pregnancy

Dang Gui Gao is an externally applied ointment, not taken internally. When used topically on burns or skin lesions as directed, systemic absorption is minimal. It is generally considered safe for external use during pregnancy. However, if large areas of broken skin are involved, some absorption of Dang Gui constituents (which have mild Blood-invigorating properties) is theoretically possible. Pregnant women with extensive burns should seek emergency medical care rather than relying on topical herbal treatment. Consult a qualified practitioner if there is any concern.

Breastfeeding

Dang Gui Gao is applied externally to the skin surface and is not taken internally. Systemic absorption through intact or mildly damaged skin is negligible, making it unlikely to transfer meaningful amounts of active constituents into breast milk. It is generally considered safe for breastfeeding mothers when used topically for minor burns or skin lesions. Avoid applying the ointment directly on or near the nipple area where an infant could ingest it during nursing. If treating a burn on the breast, clean the area thoroughly before breastfeeding.

Children

Dang Gui Gao is an external ointment and can generally be used on children for minor burns or scalds. Apply a thin layer to the affected area. For infants and young children, test a small amount on unaffected skin first to check for sensitivity. Children's skin is thinner and more permeable than adults', so avoid covering large surface areas. Any burn in a child that is larger than a small coin, or that blisters extensively, should receive professional medical attention rather than home treatment with topical ointments. Keep the ointment out of reach of children to prevent accidental ingestion.

Drug Interactions

If you are taking pharmaceutical medications, be aware of these potential interactions with Dang Gui Gao

Dang Gui Gao is applied topically and systemic absorption is minimal under normal use. No well-documented drug interactions have been reported for this external preparation. However, the following theoretical considerations apply:

  • Topical anticoagulants or blood thinners applied to the same area: Dang Gui contains compounds (such as ligustilide and ferulic acid) that have mild antiplatelet and Blood-invigorating properties. If applied to the same wound site as pharmaceutical anticoagulant creams, there is a theoretical (though clinically unlikely) risk of enhanced local bleeding.
  • Other topical wound medications: Avoid layering Dang Gui Gao with silver sulfadiazine cream or other topical burn medications without practitioner guidance, as the oil-based vehicle may interfere with the absorption or action of other topical agents.

For patients on systemic anticoagulant therapy (warfarin, heparin, etc.) with large open burn wounds, consult a healthcare provider before applying, as absorption through extensively damaged skin could theoretically be greater than through intact skin.

Usage Guidance

Practical advice for getting the most out of Dang Gui Gao

Best time to take

Apply directly to the cleaned wound and change the dressing 1 to 2 times daily. No specific time-of-day requirement for this external ointment.

Typical duration

Applied daily until the wound heals, typically 1 to 4 weeks depending on burn severity. Change dressings once or twice daily.

Dietary advice

While using Dang Gui Gao for burn treatment, avoid spicy, greasy, and overly heating foods (such as chili peppers, deep-fried foods, lamb, and strong alcohol), as these can aggravate internal Heat and slow wound healing. Favor light, nourishing foods that support tissue repair, such as congee, mung bean soup, fresh vegetables, and lean protein. Sour and fishy foods (酸腥) were traditionally advised against during topical wound treatment, as they were believed to interfere with healing and promote scarring.

Dang Gui Gao originates from Tai Ping Hui Min He Ji Ju Fang (太平惠民和剂局方) Sòng dynasty, 1078–1110 CE

Classical Texts

Key passages from the classical Chinese medical texts that first described Dang Gui Gao and its clinical use

《太平惠民和剂局方》卷八 (Tai Ping Hui Min He Ji Ju Fang, Volume 8):

「治汤火伤初起瘭浆,热毒侵展,焮赤疼痛,毒气壅盛,腐化成脓。敛疮口,生肌肉,拨热毒,止疼痛。」

Translation: "Treats burns from hot liquid or fire in their initial stage with blistering, where Heat toxin spreads outward causing redness, swelling, and pain, where toxic Qi congests and tissue rots into pus. It closes sore openings, generates flesh, draws out Heat toxin, and stops pain."

Preparation method from the same source:

「当归、黄蜡,各一两;麻油四两。上件先将油煎,令当归焦黑,去滓,次入蜡急搅之,放冷,入瓷盒内。每使时,故帛子摊贴之。」

Translation: "Dang Gui and beeswax, one liang each; sesame oil, four liang. First fry the Dang Gui in oil until it turns dark and charred, remove the residue, then add the wax and stir vigorously, let it cool, and store in a ceramic container. When applying, spread it on old cloth and plaster it on."

Historical Context

How Dang Gui Gao evolved over the centuries — its origins, lineage, and place in the broader tradition of Chinese medicine

Dang Gui Gao is the simplified name for Shen Xiao Dang Gui Gao (神效当归膏, "Miraculously Effective Dang Gui Ointment"), first recorded in the Tai Ping Hui Min He Ji Ju Fang (太平惠民和剂局方), the Song Dynasty government-compiled pharmaceutical formulary (first published in 1078 CE, with additions through the Southern Song). It appears in Volume 8 under the section on sores, wounds, and fractures (治疮肿伤折). The name "Dang Gui Gao" as an alias was noted in the Ming Dynasty text Gu Jin Yi Tong (古今医统, Volume 79).

The formula represents one of the earliest standardized topical wound-healing preparations in Chinese medicine. Its remarkably simple three-ingredient composition (Dang Gui, beeswax, and sesame oil) made it easy to prepare and widely accessible. The preparation method of frying the herb in oil until charred, then mixing with wax, is a classic technique for making oil-based medicinal pastes (油膏) that remained the standard for external wound preparations for centuries. This same foundational approach was later elaborated in more complex formulas such as Zi Yun Gao (紫云膏, Purple Cloud Ointment) and Sheng Ji Yu Hong Gao (生肌玉红膏), which added herbs like Zi Cao (Lithospermum) for additional cooling and Blood-moving effects.

A related formula also recorded in the Sheng Hui Fang (圣惠方) under the name Shen Xiao Bai Gao (神效白膏) uses a nearly identical composition with slightly different proportions (Dang Gui 1.5 liang instead of 1 liang), demonstrating the formula's widespread use across Song Dynasty medical practice.

Modern Research

A published study investigating the pharmacological effects or clinical outcomes of Dang Gui Gao

1

Proteomic Study of Angelica sinensis Wound Healing Mechanism (In Vitro, 2012)

Hsiao CY, Hung CY, Tsai TH, Chak KF. Evidence-Based Complementary and Alternative Medicine, 2012, Volume 2012, Article ID 467531.

This study used proteomic and biochemical analysis to investigate how Angelica sinensis extract and its active component ferulic acid promote wound healing in human skin fibroblasts. The extract promoted fibroblast proliferation in a dose-dependent manner, enhanced collagen secretion, and stimulated cell migration, supporting the traditional use of Dang Gui in burn and wound healing formulations.

DOI

Research on TCM formulas is growing but still limited by Western clinical trial standards. These studies provide emerging evidence and should be considered alongside practitioner expertise.