Formula

Yi Yi Fu Zi Bai Jiang San

薏苡附子败酱散

Also known as:

Bai Jiang San (败酱散, Patrinia Powder) , Yi Yi Fu Zi San (薏苡附子散)

Properties

Internal abscess-clearing formulas · Slightly Warm

Key Ingredients

Yi Yi Ren

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

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About This Formula

Traditional Chinese Medicine background and properties

Formula Description

A classical three-herb formula from the Jin Gui Yao Lue used to drain pus, reduce internal abscesses, and warm the body's Yang when it has become weakened. Originally designed for intestinal abscess (appendicitis) that has already formed pus in a person with underlying cold and deficiency, it is now also widely used for chronic pelvic inflammatory disease, ulcerative colitis, and certain stubborn skin conditions like eczema.

Formula Category

Main Actions

  • Expels Pus and Reduces Swelling
  • Warms Yang and Disperses Cold
  • Drains Dampness
  • Invigorates Blood and Reduces Swelling
  • Dissipates Nodules and Softens Hardness

TCM Patterns

In TCM, symptoms don't appear randomly — they cluster into recognizable patterns of disharmony that reveal what's out of balance in the body. Yi Yi Fu Zi Bai Jiang San is traditionally associated with these specific patterns.

The following describes this formula's classification within Traditional Chinese Medicine theory and is provided for educational purposes only.

Why Yi Yi Fu Zi Bai Jiang San addresses this pattern

This is the primary pattern described in the Jin Gui Yao Lue. An intestinal abscess (肠痈) has already formed pus, but the patient's underlying constitution is Yang-deficient. Cold-Dampness and Blood stasis have become entangled in the lower abdomen, and the decaying tissue has produced pus. Because Yang is weak, the body cannot mount a strong inflammatory response, so there is no fever (身无热), the abdomen feels soft on palpation rather than tense and painful, and the skin becomes dry and rough like fish scales (肌肤甲错) due to Blood stasis blocking nourishment to the surface. The rapid pulse (脉数) reflects the pus and toxin inside rather than external Heat. Yi Yi Ren drains the Dampness and pus, Bai Jiang Cao clears the toxin and breaks Blood stasis, and Fu Zi restores Yang to help the body complete the healing process.

A practitioner would look for one or more of these signs

Tic Disorder

Rough, dry, scaly skin (肌肤甲错)

Abdominal Distention

Abdomen appears swollen but feels soft on pressure

Abdominal Pain

Lower abdominal tightness without severe tenderness

Dull Pale Complexion

Pale face indicating Yang deficiency

Cold Limbs

Cold extremities from Yang weakness

How It Addresses the Root Cause

This formula addresses a specific and somewhat unusual type of intestinal abscess (肠痈, chang yong): one where pus has already formed internally, but the body's Yang (warming, activating force) has become weakened over the course of the illness. The underlying disease logic involves three interlocking factors: Cold-Dampness, Blood stasis, and a constitutional tendency toward Yang deficiency.

In a person whose Yang Qi is already insufficient, the body lacks the warmth and motive force to properly circulate Qi and Blood through the lower abdomen. When Dampness and Cold obstruct the intestinal region, Blood flow becomes sluggish and begins to stagnate. Over time, this stagnant Blood and accumulated Dampness putrefy and transform into pus. Crucially, unlike an acute, Heat-dominant abscess (which would present with high fever, a red face, and a forceful pulse), this pattern shows no body fever despite the internal suppuration. The pulse is rapid (indicating the presence of pus) but the overall constitution is cold and weak. The skin becomes dry and rough like fish scales (肌肤甲错, ji fu jia cuo), a hallmark sign of internal Blood stasis starving the skin of nourishment. The abdomen appears swollen and tight on the surface, yet feels soft when pressed, indicating that the swelling is from pus rather than a solid mass.

The essential disease logic is: Yang deficiency leads to Cold-Dampness accumulation, which causes Blood stasis, which putrefies into pus that the body is too weak to resolve on its own. The formula must therefore simultaneously support the weakened Yang, drain the Dampness, expel the pus, and resolve the Blood stasis, all without aggravating the underlying deficiency.

Formula Properties

Temperature

Slightly Warm

Taste Profile

Predominantly bland and slightly acrid — bland from Yi Yi Ren to drain Dampness and expel pus, acrid from Fu Zi to disperse Cold and move stagnation, with bitter from Bai Jiang Cao to clear toxins.

Target Organs
Large Intestine Spleen Lungs Stomach
Channels Entered
Large Intestine Spleen Lung Stomach

Formula Origin

Jin Gui Yao Lue (金匮要略), Chapter 18: Sores, Intestinal Abscess, and Immersion Sores

This is just partial information on the formula's TCM properties. More detailed information is available on the formula's dedicated page

Ingredients in Yi Yi Fu Zi Bai Jiang San

Detailed information about each herb in Yi Yi Fu Zi Bai Jiang San and their roles

Kings
Deputies
Assistants
Yi Yi Ren
Yi Yi Ren

Job's Tears seed

Dosage: 30 - 60g

Temperature Cool
Taste Sweet (甘 gān), Bland (淡 dàn)
Organ Affinity Spleen, Stomach, Lungs
Parts Used Seed (种子 zhǒng zǐ / 子 zǐ / 仁 rén)
Role in Yi Yi Fu Zi Bai Jiang San

The principal herb, used in the largest proportion (10 parts in the original). Yi Yi Ren clears Heat, resolves Dampness, expels pus, and benefits the intestines. It is the primary agent for draining the abscess and eliminating the accumulation of dampness and turbid matter in the lower abdomen.

Bai Jiang Cao
Bai Jiang Cao

Patrinia herb

Dosage: 15 - 30g

Temperature Slightly Cool
Taste Acrid / Pungent (辛 xīn), Bitter (苦 kǔ)
Organ Affinity Stomach, Large Intestine, Liver
Parts Used Whole plant / Aerial parts (全草 quán cǎo)
Role in Yi Yi Fu Zi Bai Jiang San

Used at 5 parts in the original formula. Bai Jiang Cao clears Heat-toxin, breaks up Blood stasis, and expels pus. It powerfully assists the King herb by directly targeting the abscess in the intestines, promoting the discharge of pus and resolution of the mass.

Lai Fu Zi
Lai Fu Zi

Radish seed

Dosage: 6 - 10g

Temperature Neutral
Taste Acrid / Pungent (辛 xīn), Sweet (甘 gān)
Organ Affinity Lungs, Spleen, Stomach
Parts Used Seed (种子 zhǒng zǐ / 子 zǐ / 仁 rén)
Role in Yi Yi Fu Zi Bai Jiang San

Used in the smallest proportion (2 parts). Fu Zi warms Yang, disperses cold-dampness, and drives stagnant Qi and Blood through areas of obstruction. It supports the body's weakened Yang, prevents the cold nature of the other two herbs from further damaging the Spleen Yang, and helps break open areas of constraint so that pus can be discharged.

Modern Research (4 studies)

  • Yiyi Fuzi Baijiang Powder Alleviates DSS-Induced Ulcerative Colitis in Rats (Network Pharmacology + Animal Study, 2023)
  • Identification of the Effect and Mechanism of YFBP Against Colorectal Cancer (Network Pharmacology + Experimental Validation, 2022)
See all research on the formula page

Usage & Safety

How to use this formula and important safety information

Important Medical Disclaimer

The information provided here is for educational purposes only and is not intended as medical advice or to replace consultation with a qualified healthcare professional. This formula is a dietary supplement and has not been evaluated by the FDA. It is not intended to diagnose, treat, cure, or prevent any disease.

Always consult with a qualified healthcare provider, particularly if you are pregnant, nursing, have a medical condition, or are taking other medications. Discontinue use and consult your healthcare provider if you experience any adverse reactions.

Recommended Dosage

Instructions for safe storage and consumption

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Best Time to Take

Traditionally taken as a single dose (顿服) on an empty stomach, or in modern practice divided into 2 doses taken 30 minutes before meals, morning and evening.

Typical Duration

Acute intestinal abscess: 1-2 weeks with reassessment; chronic conditions (pelvic inflammation, skin disease, colitis): 4-8 weeks, reassessed regularly by practitioner.

Dietary Advice

Avoid cold, raw, and greasy foods while taking this formula. Cold and raw foods (ice water, salads, raw fruit) can further damage the already weakened Yang and impede Dampness resolution. Greasy, rich, and fried foods generate more Dampness and can worsen suppuration. Alcohol and spicy, highly stimulating foods should also be limited, as they can aggravate internal Heat and inflammation. Favor warm, easily digestible foods such as congee (rice porridge), cooked vegetables, and mild soups to support the Spleen and Stomach during recovery.

Special Populations

Pregnancy

Contraindicated in pregnancy. Fu Zi (Aconite, Radix Aconiti Lateralis Praeparata) is classified as 'use with caution' during pregnancy in the Chinese Pharmacopoeia (《中国药典》). Animal studies have shown that Fu Zi extracts at doses close to clinical ranges can cause disruption of estrous cycles, decrease reproductive hormone levels, and produce mild maternal toxicity in pregnant rats. Yi Yi Ren (Coix Seed) is also traditionally cautioned in pregnancy due to its properties of promoting downward movement and draining Dampness. The combination of these two herbs makes this formula unsuitable for pregnant women.

Breastfeeding

Use with caution during breastfeeding. Fu Zi (Aconite) contains aconitine alkaloids that, while reduced through processing (炮制), may still transfer into breast milk in small amounts. No specific clinical studies have evaluated the safety of this formula during lactation. However, clinical case reports from China do exist of practitioners prescribing this formula to breastfeeding women for conditions such as eczema, suggesting it is not considered absolutely prohibited in practice. Nonetheless, the processed Aconite component warrants professional supervision, and the formula should only be used during breastfeeding under the guidance of a qualified practitioner who can monitor both mother and infant.

Pediatric Use

This formula is not commonly used in pediatric practice, but is not specifically contraindicated in children. If prescribed for a child, the dosage should be significantly reduced based on the child's age and body weight, typically to one-third to one-half of the adult dose for children over 6 years old, and further reduced for younger children. Fu Zi (Aconite) requires particular caution in children due to potential toxicity from aconitine alkaloids; it must be properly processed (炮制) and decocted for an extended time (at least 30-60 minutes) before adding other herbs. Pediatric use should only occur under close supervision by a qualified practitioner experienced in prescribing formulas containing Aconite to children.

Drug Interactions

Fu Zi (Aconite) interactions: Fu Zi contains aconitine alkaloids, which have cardiac effects. It should be used cautiously alongside cardiac glycosides (e.g. digoxin), antiarrhythmic drugs, and beta-blockers, as concurrent use may potentiate cardiac effects or arrhythmia risk. Fu Zi should not be combined with other herbs or drugs that contain or potentiate aconitine toxicity.

Yi Yi Ren (Coix Seed) interactions: Yi Yi Ren has mild blood-sugar-lowering properties. When taken concurrently with oral hypoglycemic agents or insulin, blood glucose should be monitored more closely to avoid hypoglycemia. Its mild diuretic action may also interact with pharmaceutical diuretics or lithium (by affecting lithium clearance).

General anticoagulant/antiplatelet considerations: Bai Jiang Cao (Patrinia) has Blood-moving and stasis-resolving properties. Patients taking anticoagulants (warfarin, heparin) or antiplatelet drugs (aspirin, clopidogrel) should use this formula with caution, as there is a theoretical risk of enhanced bleeding tendency.

Contraindications

Avoid

Intestinal abscess in the acute stage with high fever, strong rapid pulse, severe abdominal pain with guarding, and constipation. This presentation calls for Da Huang Mu Dan Tang or other formulas for acute, excess-Heat patterns, not this formula.

Avoid

Pregnancy. The formula contains Fu Zi (Aconite), which is classified as 'use with caution' (慎用) in pregnancy in the Chinese Pharmacopoeia. Yi Yi Ren is also traditionally cautioned in pregnancy.

Caution

Yin deficiency with vigorous Fire (阴虚火旺). The warming nature of Fu Zi can further damage Yin and inflame empty Fire.

Avoid

Active gastrointestinal bleeding, intestinal perforation, or other surgical emergencies. These require immediate medical intervention, not herbal treatment.

Caution

Intestinal abscess with purely excess-Heat signs (red face, high fever, yellow greasy tongue coating, forceful rapid pulse) and no signs of Yang deficiency. In such cases, the warming action of Fu Zi is inappropriate.

Cautions & Warnings

Yi Yi Fu Zi Bai Jiang San is typically safe for most individuals, but it can lead to side effects in some cases. Pregnant, nursing, or postpartum women, as well as those with liver conditions, should use this formula cautiously and preferably under professional supervision.

As with any Chinese herbal remedy, it is advisable to seek guidance from a qualified Traditional Chinese Medicine (TCM) practitioner before beginning treatment with Yi Yi Fu Zi Bai Jiang San.

Product Details

Manufacturing, supplier, and product specifications

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Granules

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Treasure of the East

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