Formula

Xiao Jian Zhong Tang

小建中汤

Also known as:

Shaoyao Tang (芍药汤) , Jian Zhong Tang (建中汤) , Guizhi Shaoyao Tang (桂枝芍药汤)

Properties

Interior-warming formulas · Warm

Key Ingredients

Yi Tang

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

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About This Formula

Traditional Chinese Medicine background and properties

Formula Description

A gentle, warming formula for people who experience recurring crampy abdominal pain that feels better with warmth and pressure, along with fatigue, poor appetite, and a pale complexion. It works by nourishing and warming the digestive system from within, restoring the body's ability to produce Qi and Blood. Originally designed for chronic conditions involving overall weakness and depleted constitution, it is one of the most commonly used classical formulas for both adults and children with weak digestion.

Formula Category

Main Actions

  • Warms the Middle Burner
  • Relaxes Spasms and Relieves Urgency
  • Harmonizes Yin and Yang
  • Nourishes the Spleen and Stomach
  • Harmonizes the Liver and Spleen
  • Tonifies Qi and Generates Blood

TCM Patterns

In TCM, symptoms don't appear randomly — they cluster into recognizable patterns of disharmony that reveal what's out of balance in the body. Xiao Jian Zhong Tang is traditionally associated with these specific patterns.

The following describes this formula's classification within Traditional Chinese Medicine theory and is provided for educational purposes only.

Why Xiao Jian Zhong Tang addresses this pattern

When the Spleen and Stomach lack warmth and substance, they cannot properly transform food into Qi and Blood. This leads to cramping abdominal pain that comes and goes, worsens with cold or hunger, and improves with warmth and gentle pressure. The person looks pale, feels tired, and may have poor appetite. Yi Tang and Gui Zhi directly warm and nourish the depleted Middle Burner, while Bai Shao and Zhi Gan Cao relax the spasmodic pain that results from the muscles and sinews being poorly nourished. The entire formula acts as a gentle but sustained source of warmth and nourishment for the core digestive system.

A practitioner would look for one or more of these signs

Abdominal Pain

Cramping, intermittent abdominal pain relieved by warmth and pressure

Eye Fatigue

Physical tiredness and shortness of breath

Poor Appetite

Reduced desire to eat

Dull Pale Complexion

Lusterless, sallow or yellowish face

Cold Limbs

Cold hands and feet

Loose Stools

Soft or unformed stools

How It Addresses the Root Cause

The core disease logic addressed by Xiao Jian Zhong Tang is deficiency and cold of the Middle Burner (中焦虚寒) complicated by Liver-Spleen disharmony (肝脾不和). The Middle Burner refers to the Spleen and Stomach, the body's digestive centre and the source of Qi and Blood production. When the Spleen and Stomach become depleted and cold, they can no longer adequately transform food into nourishment. This leads to a widespread shortage of Qi and Blood throughout the body.

Because the Spleen is weak, it becomes vulnerable to being "overridden" by the Liver. In the Five Phases framework, the Liver (Wood) naturally controls the Spleen (Earth). When Spleen Qi is insufficient, this controlling relationship becomes excessive, like a bully taking advantage of someone already weakened. The Liver's tightening, constricting influence on the abdomen creates the hallmark symptom: cramping, spasmodic abdominal pain that feels better with warmth and gentle pressure. The pain comes in waves because the Liver Qi tenses the muscles and sinews of the abdomen when the Spleen lacks the strength to resist.

The downstream consequences of this Middle Burner deficiency are wide-ranging. Insufficient Blood production leads to palpitations, a pale complexion, and nosebleeds (Blood failing to stay in the vessels). Inadequate nourishment of the limbs causes aching and soreness. The deficiency can also generate a kind of "false Heat" where the body's Yin and Yang become mildly unbalanced: the hands and feet feel uncomfortably warm, the throat becomes dry, and there may be restless dreams. These Heat-like signs arise not from excess, but from the body's depleted state. This is why the Jin Gui Yao Lue describes such a complex mix of seemingly contradictory symptoms all under one formula: they all trace back to the same root cause of Middle Burner deficiency failing to generate and regulate Qi, Blood, Yin, and Yang.

Formula Properties

Temperature

Warm

Taste Profile

Predominantly sweet with mild sour and pungent notes. The sweetness (from maltose, licorice, and jujube) tonifies and nourishes the Middle Burner; the sour (from doubled Peony) restrains Yin and relaxes spasm; the pungent (from Cinnamon Twig and Ginger) gently warms and circulates.

Target Organs
Spleen Stomach Liver Heart
Channels Entered
Spleen Stomach Liver Heart

Formula Origin

Shang Han Lun (傷寒論) by Zhang Zhongjing

This is just partial information on the formula's TCM properties. More detailed information is available on the formula's dedicated page

Ingredients in Xiao Jian Zhong Tang

Detailed information about each herb in Xiao Jian Zhong Tang and their roles

Kings
Deputies
Assistants
Envoys
Yi Tang
Yi Tang

Maltose syrup

Dosage: 30 - 60g

Temperature Warm
Taste Sweet (甘 gān)
Organ Affinity Spleen, Stomach, Lungs
Parts Used Processed / Derived product (加工品 jiā gōng pǐn)
Role in Xiao Jian Zhong Tang

Sweet and warm, Yi Tang is the principal herb that directly nourishes and warms the Middle Burner (Spleen and Stomach). It supplements Qi, relaxes muscular spasm in the abdomen, and moderates cramping pain. Its rich sweetness provides direct nourishment to the depleted digestive system.

Bai Shao
Bai Shao

White peony root

Dosage: 18g

Temperature Slightly Cool
Taste Bitter (苦 kǔ), Sour (酸 suān)
Organ Affinity Liver, Spleen
Parts Used Root (根 gēn)
Role in Xiao Jian Zhong Tang

Used at double the dosage of Gui Zhi, Bai Shao nourishes Blood and Yin, softens the Liver, and relieves abdominal cramping. Its sour and cooling nature complements the sweet warmth of Yi Tang to form the 'sour-sweet generates Yin' (酸甘化阴) pairing, addressing the nutritive Yin deficiency underlying the pattern.

Gui Zhi
Gui Zhi

Cinnamon twig

Dosage: 9g

Temperature Warm
Taste Acrid / Pungent (辛 xīn), Sweet (甘 gān)
Organ Affinity Heart, Lungs, Urinary Bladder
Parts Used Twig (枝 zhī)
Role in Xiao Jian Zhong Tang

Warms Yang, dispels Cold from the interior, and promotes the circulation of Qi and Blood through the channels. Its pungent-sweet warmth pairs with Zhi Gan Cao in a 'pungent-sweet generates Yang' (辛甘化阳) combination, restoring Spleen Yang and the body's warming function.

Gan Cao
Gan Cao

Licorice root

Dosage: 6g

Temperature Neutral
Taste Sweet (甘 gān)
Organ Affinity Heart, Lungs, Spleen, Stomach
Parts Used Root (根 gēn)
Role in Xiao Jian Zhong Tang

Tonifies Qi of the Middle Burner, relieves spasmodic pain together with Bai Shao (the classical Shao Yao Gan Cao Tang pairing embedded within this formula), and harmonizes all the other herbs in the formula.

Sheng Jiang
Sheng Jiang

Fresh ginger rhizome

Dosage: 9g

Temperature Slightly Warm
Taste Acrid / Pungent (辛 xīn)
Organ Affinity Lungs, Spleen, Stomach
Parts Used Rhizome (根茎 gēn jīng)
Role in Xiao Jian Zhong Tang

Warms the Stomach, assists Gui Zhi in dispersing Cold, and helps the Spleen and Stomach transport fluids. Together with Da Zao, it harmonizes the nutritive and protective aspects of the body.

Da Zao
Da Zao

Jujube fruit

Dosage: 4 - 12 pieces

Temperature Warm
Taste Sweet (甘 gān)
Organ Affinity Spleen, Stomach, Heart
Parts Used Fruit (果 guǒ / 果实 guǒ shí)
Role in Xiao Jian Zhong Tang

Supplements Spleen Qi and nourishes Blood. Together with Sheng Jiang, it regulates the nutritive and protective Qi, and with the sweet herbs reinforces the Middle Burner's function as the source of Qi and Blood production.

Modern Research (4 studies)

  • Meta-analysis of Jianzhong Decoction for Peptic Ulcers (58 RCTs, 2017)
  • Genoprotective Effect of Xiao Jian Zhong Tang (In Vitro Study, 2013)
See all research on the formula page

Usage & Safety

How to use this formula and important safety information

Important Medical Disclaimer

The information provided here is for educational purposes only and is not intended as medical advice or to replace consultation with a qualified healthcare professional. This formula is a dietary supplement and has not been evaluated by the FDA. It is not intended to diagnose, treat, cure, or prevent any disease.

Always consult with a qualified healthcare provider, particularly if you are pregnant, nursing, have a medical condition, or are taking other medications. Discontinue use and consult your healthcare provider if you experience any adverse reactions.

Recommended Dosage

Instructions for safe storage and consumption

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Best Time to Take

30 minutes before meals on an empty stomach, warm, divided into 2-3 doses per day. Taking before meals enhances absorption and allows the formula to directly nourish the Middle Burner.

Typical Duration

Often taken for 2-4 weeks for acute abdominal pain, or 4-12 weeks as a constitutional tonic. Long-term use for body constitution improvement (especially in children) may extend to several months under practitioner supervision.

Dietary Advice

While taking this formula, favor warm, easily digestible, and mildly nourishing foods: well-cooked grains (rice congee, millet porridge), soups, steamed vegetables, and lightly cooked proteins. These support the Spleen and Stomach's recovering digestive function. Avoid cold and raw foods (salads, ice cream, cold drinks, raw fruits in excess), greasy or deep-fried foods, and overly spicy dishes. These burden a weakened digestive system. Also avoid excessive dairy, which can generate Dampness and impair Spleen function. Alcohol should be avoided as it produces Damp-Heat and irritates the stomach lining. Meals should be regular, moderate in portion, and eaten in a calm setting. Chewing thoroughly aids the Spleen's transforming function.

Special Populations

Pregnancy

Generally considered safe during pregnancy, as none of the ingredients are classified as strongly contraindicated in pregnancy. The formula is gentle, tonifying, and nourishing. However, Gui Zhi (Cinnamomi Ramulus) is warm and mildly activating of circulation, so caution is warranted in pregnancies with a history of bleeding or threatened miscarriage. Gan Cao (Glycyrrhizae Radix) in prolonged or high-dose use has been associated with mineralocorticoid-like effects (water retention, elevated blood pressure) and some evidence suggests it may slightly increase the risk of preterm birth. Use should be under the guidance of a qualified practitioner, who can adjust the formula appropriately.

Breastfeeding

Xiao Jian Zhong Tang is generally considered compatible with breastfeeding. All ingredients are food-grade or commonly used gentle herbs. Yi Tang (maltose) is a food product. Gui Zhi, Bai Shao, Sheng Jiang, Da Zao, and Zhi Gan Cao are mild in nature. The formula is traditionally used for postpartum women with abdominal pain (as indicated in the Jin Gui Yao Lue). However, Gan Cao (Licorice) in sustained high doses may theoretically affect fluid balance. Standard therapeutic doses for a normal course of treatment are not expected to pose risks to the nursing infant. Consult a qualified practitioner for guidance.

Pediatric Use

Xiao Jian Zhong Tang is one of the most celebrated pediatric formulas in TCM and in Japanese Kampo medicine (where it is known as Shokenchuto). It is widely used for children who are thin, pale-complexioned, have poor appetite, crave sweets, and suffer from recurrent abdominal pain. The formula is considered safe and gentle enough for long-term use to improve a child's overall constitution. Dosage should be reduced proportionally based on the child's age and weight. A common guideline: children under 3 years use about one-quarter of the adult dose; ages 3-6 use about one-third; ages 6-12 use about one-half. The maltose (Yi Tang) component makes the formula naturally palatable and sweet, which children generally accept readily. For very young children (under 1 year), consult a pediatric TCM specialist before use.

Drug Interactions

Gan Cao (Licorice) interactions: Gan Cao (Glycyrrhizae Radix) in this formula contains glycyrrhizic acid, which has aldosterone-like effects and can cause sodium retention and potassium excretion. This creates several important drug interaction concerns:

  • Digoxin and cardiac glycosides: Gan Cao can lower blood potassium levels, which increases the heart's sensitivity to cardiac glycosides and may trigger digoxin toxicity (arrhythmias, nausea). Concurrent use should be avoided or closely monitored.
  • Potassium-depleting diuretics (furosemide, hydrochlorothiazide): Combined use with Gan Cao may worsen potassium depletion and increase the risk of hypokalemia-related complications such as muscle weakness and cardiac arrhythmias.
  • Antihypertensive medications: Gan Cao's sodium- and water-retaining effects can counteract blood pressure lowering drugs, reducing their effectiveness.
  • Warfarin: Some evidence suggests Gan Cao may interact with warfarin metabolism, potentially altering its anticoagulant effect.
  • Corticosteroids: Gan Cao can inhibit the metabolism of hydrocortisone and similar drugs, increasing their blood levels and potentially worsening side effects such as fluid retention and high blood pressure.
  • Hypoglycemic agents (insulin, metformin, sulfonylureas): Gan Cao has glucocorticoid-like properties that can raise blood sugar, potentially counteracting diabetes medications.

Yi Tang (Maltose) consideration: The high sugar content of maltose may affect blood glucose levels in patients taking diabetes medications.

These interactions are most clinically relevant with prolonged use or higher doses. Short-term use at standard doses carries lower risk, but patients on any of the above medications should inform their prescribing physician.

Contraindications

Avoid

Vomiting (呕家): The Shang Han Lun itself states that people who tend to vomit should not use Jian Zhong Tang because of its sweet taste (from Yi Tang / maltose), which can worsen nausea and vomiting.

Avoid

Epigastric or abdominal fullness and distension (中满): The sweet, cloying nature of maltose (Yi Tang) can worsen feelings of bloating and fullness in the abdomen, especially when there is Dampness or food stagnation.

Avoid

Yin deficiency with vigorous Fire (阴虚火旺) causing stomach pain: This formula is warming in nature. Using it in a Heat pattern or Yin-deficient Fire condition would add fuel to the fire, worsening symptoms like burning pain, thirst, and irritability.

Caution

Damp-Heat accumulation in the Middle Burner: Symptoms such as a greasy yellow tongue coating, bitter taste, foul breath, and sticky stools indicate Damp-Heat. The sweet and warm nature of this formula would aggravate these conditions.

Caution

Diabetes or blood sugar disorders: The principal ingredient maltose (Yi Tang) has a high sugar content and can cause blood sugar fluctuations. People with diabetes should avoid this formula or use it under strict medical supervision.

Caution

Active infection or high fever: During acute febrile illness with strong pathogenic factors, tonifying the interior with sweet and warm herbs is inappropriate and may trap the pathogen inside.

Cautions & Warnings

Xiao Jian Zhong Tang is typically safe for most individuals, but it can lead to side effects in some cases. Pregnant, nursing, or postpartum women, as well as those with liver conditions, should use this formula cautiously and preferably under professional supervision.

As with any Chinese herbal remedy, it is advisable to seek guidance from a qualified Traditional Chinese Medicine (TCM) practitioner before beginning treatment with Xiao Jian Zhong Tang.

Product Details

Manufacturing, supplier, and product specifications

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Granules

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